Medicine Advances最新文献

Around 65 million individuals suffer from epilepsy worldwide, and when it is not properly treated, it is linked to higher rates of physical harm and mortality. Due to the requirement for long-term therapy and the side effects of many medications, medication compliance is a significant issue. The purpose of this review was to summarize the findings of previous studies examining the quality of life (QOL), adherence, patient education, and medication knowledge, as well as the impact of a pharmacist-led educational intervention. Additionally, to find out if these studies benefit epileptic patients, to find the appropriate method used to help them in all aspects of their lives, and to use these in future studies. A systematic and comprehensive search was conducted using specific keywords from PubMed, Google Scholar, and Research Gate. A significantly poorer QOL was linked to prolonged antiepileptic drug use or poor adherence as well as psychiatric problems. Neglect was the most frequent reason for nonadherence. The frequency of seizures was greatly reduced, and the adherence was significantly increased by patient education and medication understanding. Patient awareness, adherence, QOL, and seizure frequency were dramatically improved following the intervention. In the absence of optimal treatment, epilepsy is associated with increased rates of bodily injuries and mortality. It is crucial to increase patient education and knowledge about disease and treatment in order to improve adherence, and QOL. Intervention by a chemist is required to achieve these results.

The retrograde approach is a principal procedure used in coronary chronic total occlusion percutaneous coronary intervention. However, the retrograde approach presents more challenges compared with the antegrade approach, as it is associated with a lower rate of success and a higher risk of complications. An accurate pre-procedural evaluation of the complexity of a lesion could aid in the planning of the procedure, in estimating the procedure's duration, or in determining whether the patient should be referred to another center specializing in CTO-PCI, as well as in a more precise evaluation of the risk-benefit ratio. In recent years, multiple scoring systems have been created to forecast the success and efficiency of the retrograde procedure. However, each scoring system was developed independently, and comparative studies were lacking. This article provides a review of these scoring systems, offers an overview of the current state of the retrograde approach, and aims to stimulate further discussion on this topic.

Despite the recent successes of cancer therapy, numerous obstacles remain. The medical community of the 16^th century believed that magnets might be used to cure or prevent illness. However, this concept has only recently been put into practice in the treatment of cancer. Cancers vary greatly not only at the patient, tissue, and cellular levels but also at the molecular level. Because of this multiscale heterogeneity, effective treatments that not only differentiate between cancerous and healthy tissues but also target a wide variety of tumor subclones are difficult to develop. Most treatments either take advantage of a specific biological characteristic shared by cancer cells (e.g., their propensity for rapid division) or indiscriminately eradicate every cell in an area of interest. In this article, we review the physical, chemical, electrical, optical, and magnetic properties of cancer cells, before discussing how these properties may be modulated by current and future cancer therapies.

Salamanders possess remarkable regenerative capacities for organ regeneration among tetrapod vertebrates. Previous research has primarily focused on studying the regeneration of canonical tissues or organs such as limbs, tail, brain, spinal cord, heart, and lens. The advancements made in these areas have broader implications for understanding regeneration and developing therapeutic approaches for these organs, not only in salamanders but also in other vertebrates. In recent years, there has been an increasing interest in studying the regeneration of non-canonical organs in salamanders, such as the liver, lungs, kidneys, and pancreas. This diversification of research has opened up new avenues and provided potential solutions to challenging clinical problems. This review aims to summarize the progress made in the field of non-canonical organ regeneration in salamanders and provides an outlook on future research directions.

Pemphigoid, a rare autoimmune skin disease affecting the elderly, requires effective pharmacy management. This includes medication therapy, patient education, and counseling. Understanding pharmacokinetics and potential drug interactions are crucial for optimal treatment and minimizing adverse effects. In this case, the patient is a 65-year-old male who was diagnosed with pemphigoid 2 months ago. He is currently taking prednisone, an oral corticosteroid, to manage the symptoms. The pharmacist plays a crucial role in medication therapy by monitoring the patient's response to the medication and adjusting the dosage if necessary. Additionally, patient education is vital in ensuring that the patient understands the importance of adherence to the medication regimen and the potential side effects. The pharmacist can also provide counseling on lifestyle modifications and self-care measures to alleviate symptoms and improve the quality of life. Overall, effective pharmacy management is essential for optimizing treatment outcomes and promoting patient well-being in pemphigoid cases. The pharmacist's role in pemphigoid cases is crucial for effective medication management and patient education. They monitor the patient's response to treatment, make necessary adjustments, and empower them to take an active role in managing their condition. This approach ultimately improves the overall well-being of patients with pemphigoid.

Medicine Advances is a platform dedicated to sharing cutting-edge research, insights, and advancements in the field of medicine. As the Editor-in-Chief, it is my privilege to guide this journal towards its mission of promoting knowledge, innovation, and excellence in healthcare.

The aim of Medicine Advances is to provide a platform for researcher, scholars, and practitioners in healthcare to communicate and share their scientific findings and innovations. The journal is committed to promoting new medical theories, exchanging new clinical technologies, presenting new medical products, and accelerating the pace of medical development. This journal is dedicated to publishing high-quality original research articles, review articles, survey articles, case reports, editorials, and short communications.

In 2023, we successfully launched the Medicine Advances and published 4 issues containing 37 high-quality articles. Among the published papers, the majority were original articles (19), accounting for 51%, followed by “review” and “case report” (8 and 2, respectively). Among these submissions, the proportion of Chinese authors is the highest (58%). But the manuscripts from India, Egypt, and the United States accounted for 32%.

We have successfully established a WeChat public account in China, enhancing our accessibility and outreach. A total of 37 WeChat public account articles were published, and the articles and the journal received effective publicity. At the same time, we also promote on some international social media sites, like Twitter, Linkedin and ResearchGate.

The continued publicity resulted in good downloads and citations. Our articles' readership and download rates have shown a consistent upward trend, which is a testament to our collective efforts. Together, these articles have amassed over 12,000 downloads and 5 citations.

The involvement of 87 globally renowned experts in various medical specialties as our editorial members has significantly elevated our influence abroad. Seventeen of the 37 articles were from the journal's editorial board. The editorial board has made great contributions to the development of the journal.

The enthusiastic reception of our special issues, “Application of Omics in Diseases” and “CardioRenal Research,” inspires us to delve even deeper into these critical fields, evidence of our journal's synergy with the scientific community's pulse.

The journal's progress has grown substantially since its inception. I would like to express my heartfelt gratitude to our authors, reviewers, and readers for their continuous support and dedication. Thank you for being a part of our journey. Your contributions are what make our journal thrive and evolve. Together, we can shape the future of medicine and healthcare, making a positive impact on the lives of millions.

Xueqing Yu: Conceptualization; writing original draft; review; editing.

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