Oral Surgery, Oral Medicine, Oral Pathology最新文献

Serum transaminase levels (serum glutamic-oxaloacetic transaminase or serum glutamic-pyruvic transaminase) were found to be altered in 40 (21.39%) of 187 patients with oral lichen planus. The patients with oral lichen planus who had altered transaminase levels were on average older than those without liver disorders and exhibited a higher percentage of erosive lesions (p < 0.05) and tongue involvement. Histologically, no statistically significant differences were noted in the extension of inflammatory infiltration or in connective tissue density; nevertheless, the latter was greater in patients without altered transaminase levels. Finally, among those patients with altered liver test results and erosive lichen planus, serum glutamic-oxaloacetic transaminase and serum glutamic-pyruvic transaminase levels were found to be higher than levels in those patients without erosions. This indicates that behavior of the oral lesions is more aggressive as the degree of liver alteration increases. We emphasize that of the 40 patients with altered transaminase levels (all later proved to reflect chronic hepatitis through complementary diagnostic methods), 28 had hepatitis C virus infection.

This article describes the computed tomographic and conventional radiographic findings for florid cemento-osseous dysplasia. A low-density thin layer or cystlike area was observed around the high-density masses in the tooth-bearing area in the seven cases studied. Expansion of the buccal and lingual cortical plates was observed in association with cystlike areas, but was infrequently observed in florid cemento-osseous dysplasia not having such areas. The computed tomographic number of the high-density masses ranged from 772 to 1587 Hounsfield Units and was equivalent to that of cementum or cortical bone.

The efficacy of a topically administered miconazole denture lacquer was compared with that of a placebo lacquer in the treatment of Candida-infected denture stomatitis. The study was a double-blind, randomized, controlled clinical trial with two parallel treatment groups. The lacquer was applied once on the fitting denture surface. Follow-up examinations took place on days 3, 7, 14, 21, 28, and 35. On day 14 the effect of the treatment was assessed. Thirty-six patients were included in the statistical analysis. Eighteen received miconazole and 18 received placebo lacquer. Primary efficacy endpoints were the number of colonies cultured from the palatal mucosa and denture surface on day 14. Thirteen of 16 patients in the miconazole group A showed < 10 colonies on culture medium on day 14 in the specimens from the palatal mucosa as did 5 of 18 patients in the placebo group B (p < 0.05). Corresponding results for the denture surface were 6 of 17 and 3 of 18, respectively (p < 0.05). Reapplication of lacquer was considered necessary (> 100 colonies in at least one sampling site within 14 days) in 35% of the patients from group A and in 83% of the patients from group B. The results indicate that a single application of a miconazole denture lacquer considerably reduces the number of Candida yeasts for a substantial period of time.

Smoking, alcohol, and familial background are considered major cofactors in the cause of oral cancer. The purpose of the present study was to determine the relationship between ethnic origin and oral cancer in the Israeli Jewish Population. Data were collected during the years 1970 to 1980 from 342 dental records of patients in Israeli hospitals. Results showed a male/female ratio of 2:1. Of 264 patients with clearly determined ethnic origin, 72% were Ashkenazi, 15% Sephardi, and 13% Eastern ethnic origin. The relative prevalence showed that the risk of the Ashkenazi group to develop oral cancer was at least twice as high as the other two ethnic groups. The increase in occurrence of oral cancer with age in each ethnic group was highly significant (p < 0.001). The most common type of malignancy was squamous cell carcinoma (95%) with 99% of this malignancy occurring in patients in their sixth and seventh decade. A significant (p < 0.02) relationship between site of involvement and ethnic origin was also noted. The tongue was the leading site in the Ashkenazi and Sephardi groups, whereas the lip and alveolar ridges were the most affected sites in the Eastern ethnic group.

The effect of six endodontic irrigants on smear layers created by hand instrumentation was evaluated in vitro in the middle and apical sections of 53 root canals. The irrigants evaluated were: 1% and 5% sodium hypochlorite, a combination of 24% phosphoric acid and 10% citric acid, 0.2%, 17%, and 3% ethylenediaminetetraacetic acid. After instrumentation and treatment with the respective irrigants, the root canal specimens were examined by scanning electron microscopy to determine the presence or absence of smear layer. The two sodium hypochlorite solutions did not remove the smear layer, even when 5% sodium hypochlorite was scrubbed on the dentinal walls. The 0.2% ethylenediaminetetraacetic acid solution was more effective than sodium hypochlorite, but it did not completely remove the smear layer, especially at the orifices of the dentinal tubules. The other three solutions effectively removed the smear layer, but no significant difference was found between them (p > 0.05). The solution of 3% ethylenediaminetetraacetic acid was as effective as phosphoric-citric acid and 17% ethylenediaminetetraacetic acid. Ethylenediaminetetraacetic acid, however, did not show the marked demineralizing effect on the dentinal walls and tubules as the acidic solution.

Root perforations that result in a communication of the root space with the periodontal tissues occasionally occur during endodontic procedures. They may be induced iatrogenically, by resorptive process, or by caries. Identification of root perforations is possible by direct observation of bleeding, indirect bleeding assessment using a paper point, radiography, and an apex locator. Prognosis of a tooth with root perforation depends on the time lapsed before obturation of the perforation, location and size of the lesion, and the sealability of the repair material. Perforation defects may be repaired by nonsurgical or surgical techniques. A review of causes, diagnosis, prognosis, and management of root perforations provides information for avoiding, detecting, and treating of such defects.

Lesch-Nyhan syndrome is a rare anomaly consisting of a deficiency in the production of hypoxanthine phosphoribosyltransferase that leads to the overproduction of purine and the accumulation of uric acid. Major manifestations include mental retardation and self-destructive behavior resulting in self-mutilation through biting and scratching. Because no medical treatment exists to alleviate the symptoms of self-mutilation, direct dental intervention is the only way these behaviors can be affected. A unique case of this type involving two male identical twins is reported.

Literature reviews of oral lesions frequently lack an appropriate historic perspective, presuming that the mid- to late-twentieth century reports are the first valid reports available. The mid-nineteenth century dental journals, however, are replete with clinical, surgical, and microscopic descriptions of oral tumors and cysts. Most of these have never been referenced during the present century. The purpose of this article is to report the earliest dental journal references for a variety of odontogenic tumors and cysts. These references are derived from a canvass of all dental journals published from the first journal (American Journal of Dental Science) in 1839 to the appearance of Dental Cosmos and the organization of the American Dental Association in 1860.

The morbidity of bone harvest was compared between anterior lateral and medial surgical approaches in a randomized prospective study. Forty consecutive patients, each requiring a minimum 40 cc of loose corticocancellous bone for maxillofacial reconstruction, were randomly placed into two equal groups. Morbidity vectors assessed included bone volume, blood loss, length of surgery, length of hospital stay, incidence of seroma, incidence of anterior thigh paresthesia, postoperative pain, and gait disturbance. The results demonstrated no significant difference in morbidity between these two approaches; therefore selection of either approach is the surgeon's personal preference. A thorough understanding of the osseous anatomy of the anterior ilium and its muscular attachments, a good surgical technique, an efficient surgical team, and a continuous flow of required surgical instruments are essential to reduce the morbidity of bone harvest.

In this article two case reports of pyostomatitis vegetans are presented. Both cases were associated with inflammatory bowel disease and one case was also associated with liver dysfunction. It has recently been reported that there may be a link between liver dysfunction and pyostomatitis vegetans. The management of the condition is illustrated and the literature on the subject is reviewed.