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Climate change and mental health: The urgent warning of Brazil and Spain's 2024 catastrophic floods. 气候变化与心理健康:巴西和西班牙2024年特大洪水的紧急预警。
0 PSYCHIATRY Pub Date : 2024-12-17 DOI: 10.1016/j.sjpmh.2024.12.001
Daniel Prates-Baldez, Felipe Rech Ornell, Juliana Nichterwitz Scherer, Santiago Madeira Diefenthaeler, Flávio Kapczinski, Vicent Balanzá-Martínez, Simone Hauck
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引用次数: 0
Prediction of pharmacological response in OCD using machine learning techniques and clinical and neuropsychological variables. 利用机器学习技术和临床及神经心理学变量预测强迫症的药物反应。
0 PSYCHIATRY Pub Date : 2024-11-15 DOI: 10.1016/j.sjpmh.2024.11.001
Maria Tubío-Fungueiriño, Eva Cernadas, Manuel Fernández-Delgado, Manuel Arrojo, Sara Bertolin, Eva Real, José Manuel Menchon, Angel Carracedo, Pino Alonso, Montse Fernández-Prieto, Cinto Segalàs

Introduction: Obsessive compulsive disorder is associated with affected executive functioning, including memory, cognitive flexibility, and organizational strategies. As it was reported in previous studies, patients with preserved executive functions respond better to pharmacological treatment, while others need to keep trying different pharmacological strategies.

Material and methods: In this work we used machine learning techniques to predict pharmacological response (OCD patients' symptomatology reduction) based on executive functioning and clinical variables. Among those variables we used anxiety, depression and obsessive-compulsive symptoms scores by applying State-Trait Anxiety Inventory, Hamilton Depression Rating Scale and Yale-Brown Obsessive Compulsive Scale respectively, while Rey-Osterrieth Complex Figure Test was used to assess organisation skills and non-verbal memory; Digits' subtests from Wechsler Adult Intelligence Scale-IV were used to assess short-term memory and working memory; and Raven's Progressive Matrices were applied to assess problem solving and abstract reasoning.

Results: As a result of our analyses, we created a reliable algorithm that predicts Y-BOCS score after 12 weeks based on patients' clinical characteristics (sex at birth, age, pharmacological strategy, depressive and obsessive-compulsive symptoms, years passed since diagnostic and Raven's Progressive Matrices score) and Digits' scores. A high correlation (0.846) was achieved in predicted and true values.

Conclusions: The present study proves the viability to predict if a patient would respond or not to a certain pharmacological strategy with high reliability based on sociodemographics, clinical variables and cognitive functions as short-term memory and working memory. These results are promising to develop future prediction models to help clinical decision making.

简介强迫症与执行功能受影响有关,包括记忆力、认知灵活性和组织策略。根据以往研究的报告,执行功能得到保护的患者对药物治疗的反应较好,而其他患者则需要不断尝试不同的药物治疗策略:在这项工作中,我们使用机器学习技术,根据执行功能和临床变量预测药物治疗反应(强迫症患者症状减轻)。在这些变量中,我们分别采用了国家特质焦虑量表(State-Trait Anxiety Inventory)、汉密尔顿抑郁评定量表(Hamilton Depression Rating Scale)和耶鲁-布朗强迫症量表(Yale-Brown Obsessive Compulsive Scale)来评估焦虑、抑郁和强迫症症状的得分,同时采用了雷伊-奥斯特里赫斯复杂图形测验(Rey-Osterrieth Complex Figure Test)来评估组织能力和非语言记忆;采用韦氏成人智能量表-IV的数字分测验(Digits' subtests)来评估短时记忆和工作记忆;采用瑞文渐进矩阵(Raven's Progressive Matrices)来评估问题解决能力和抽象推理能力:经过分析,我们创建了一种可靠的算法,可以根据患者的临床特征(出生时的性别、年龄、药物治疗策略、抑郁和强迫症状、诊断后的年限以及瑞文渐进矩阵得分)和Digits得分预测12周后的Y-BOCS得分。预测值与真实值的相关性很高(0.846):本研究证明,根据社会人口统计学、临床变量和认知功能(如短期记忆和工作记忆)来预测患者是否会对某种药物治疗策略产生反应是可行的,而且可靠性很高。这些结果有望开发出未来的预测模型,帮助临床决策。
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引用次数: 0
Luis Martín-Santos: A multidimensional psychiatrist. "路易斯-马丁-桑托斯:多维精神病学家"。
0 PSYCHIATRY Pub Date : 2024-11-12 DOI: 10.1016/j.sjpmh.2024.10.002
José Lázaro
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引用次数: 0
Validación transcultural de la escala Yale Food Addiction Scale for Children (YFAS-C) al idioma español para evaluar la adicción a la comida en población pediátrica (S-YFAS-c 西班牙文耶鲁儿童食物成瘾量表(YFAS-C)的跨文化验证,用于评估儿科人群的食物成瘾情况(S-YFAS-c
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.rpsm.2021.11.006
Néstor Benítez Brito , Berta Pinto Robayna , Yolanda Ramallo Fariña , Francisco Moreno Redondo , Beatriz León Salas , Carlos Díaz Romero

Introduction

The scale The Yale Food Addiction Scale Children (YFAS-c) is the first measure designed to evaluate food addiction in children. However, this tool is not adapted to the Spanish language.

Material and methods

A translation, adaptation and methodological validation of the YFAS-c tool into the Spanish language is carried out. Initially, the scale is translated and adapted through blinded and independent translators, estimating their adaptability and agreement (Cohen's Kappa). Subsequently, the questionnaire is submitted to a committee of experts to evaluate the cultural suitability, representativeness and face and content validity using the content validity ratio (CVR), its version modified by Tristán (CVR’) and the Content Validity Index (CVI). Finally, linguistic comprehension is evaluated in a target sample using the Chi-square test.

Results

Difficulty in cross-cultural adaptability of the questionnaire among translators was low (mean: 1.96, DE: 1.40; Kappa agreement: 0.32, P = .01). The evaluation of the tool by the expert committee obtained high indices: clarity (n = 0.83), precision (n = 0.83), comprehension (n = 0.84) and content relevance (n = 0.83). Of the total of 25 items, only one item presented difficulties in understanding by age groups (P = .02).

Conclusions

A validated version, translated and adapted to the Spanish language (S-YFAS-c) has been obtained that will be able to evaluate food addiction in Spanish-speaking children.
导言:耶鲁儿童食物成瘾量表(YFAS-c)是首个用于评估儿童食物成瘾的量表。材料和方法 将 YFAS-c 工具翻译成西班牙语,并对其进行改编和方法验证。首先,由独立的盲人翻译人员对量表进行翻译和改编,评估其适应性和一致性(Cohen's Kappa)。随后,问卷被提交给一个专家委员会,由其使用内容效度比(CVR)、经特里斯坦修改的版本(CVR')和内容效度指数(CVI)对问卷的文化适宜性、代表性、表面效度和内容效度进行评估。最后,使用卡方检验对目标样本的语言理解能力进行了评估。结果译者对问卷的跨文化适应性的难度较低(平均值:1.96,DE:1.40;Kappa 协议:0.32,P = .01)。专家委员会对该工具的评估获得了较高的指数:清晰度(n = 0.83)、精确度(n = 0.83)、理解力(n = 0.84)和内容相关性(n = 0.83)。在总共 25 个条目中,只有一个条目在不同年龄组的理解上存在困难(P = .02)。结论 经过翻译和改编为西班牙语的有效版本(S-YFAS-c)已经问世,可用于评估西班牙语儿童的食物成瘾情况。
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引用次数: 0
Satisfacción percibida con los ingresos en unidades de hospitalización breve psiquiátricas: diseño y validación del cuestionario PSYQUEST 入住精神科短期住院病房的感知满意度:PSYQUEST 问卷的设计与验证
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.rpsm.2021.10.001
Clara Cocho Santalla , Ignacio Vera López , Belén Bardón Rivera , María Dolores Gómez Olmeda , Rosa Duque Domínguez , Patricia Fadón Martín , Margarita Blanco Prieto , Silvia García Jorge , Ángeles Martínez Hernanz , Almudena Molina Serrano , Encarnación Mollejo Aparicio , Patricia Nava García , Mercè Salvador Robert , Eva María Sánchez Morla , Belén Sanz-Aranguez Ávila , Alicia Vives Luengo , María Rosario Martínez Arias , Francisco Javier Sanz Fuentenebro

Introduction

Despite of the evidence pointing out the importance of evaluating patient's satisfaction regarding medical services, there are no available tools validated in Spanish to assess perceived satisfaction regarding psychiatric hospitalization in acute units.

Objective

To design and validate a tool to assess perceived satisfaction regarding hospitalization in psychiatric short-term units (STU).

Method

A multicenter, cross-sectional study was conducted in 14 STU of Madrid public hospitals. A total of 370 patients participated in the study. A preliminary questionnaire version was assessed for content validity by an expert and a patient focus group. A psychometrical validation analysis was carried out. Reliability was examined based on Cronbach's alpha and Omega coefficients, construct validity was evaluated using exploratory (EFA) and confirmatory factor analysis (CFA) and predictive criterion validity was explored through multiple linear regression analysis.

Results

PSYQUEST is a questionnaire made up of 20 items grouped under 4 dimensions (information and patient-doctor relationship, health staff care, services provided and general satisfaction). It explains 75,52% of the variance. PSYQUEST showed good reliability (α=0,88 / ω=0,89) and criterion-based validity. Lower scores were found among patients with involuntary admissions, scarce clinical improvement or restrictive measures.

Conclusion

PSYQUEST showed good psychometric qualities. It can be used for evaluating inpatient satisfaction with psychiatric admissions.
引言尽管有证据表明评估患者对医疗服务满意度的重要性,但目前还没有经过西班牙语验证的工具可用于评估患者对急诊科精神科住院治疗的满意度。方法在马德里 14 家公立医院的精神科短期病房开展了一项多中心横断面研究。共有 370 名患者参与了研究。专家和患者焦点小组对初步问卷版本的内容有效性进行了评估。此外,还进行了心理测量学验证分析。根据克朗巴赫系数(Cronbach's alpha)和奥米加系数(Omega coefficients)检验了信度,使用探索性因子分析(EFA)和确证性因子分析(CFA)评估了建构效度,并通过多元线性回归分析探讨了预测标准效度。它能解释 75.52% 的方差。PSYQUEST 显示出良好的可靠性(α=0,88 / ω=0,89)和基于标准的有效性。结论PSYQUEST显示出良好的心理测量质量。结论PSYQUEST具有良好的心理测量学特性,可用于评估住院病人对精神科住院治疗的满意度。
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引用次数: 0
Validation study of the Spanish brief version of TEMPS-A 西班牙文简短版 TEMPS-A 验证研究。
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.rpsm.2021.08.002
Jessica Zapata-Téllez , Hiram Ortega-Ortiz , Lizette Quiroz-Casián , Claudia Becerra-Palars , María del Carmen Elizabeth Lara-Muñoz , Gustavo H. Vázquez

Introduction

Identifying affective temperaments could be useful both for understanding the normal behavioral variations in the general population and to establish if there is a clinical predisposition to certain disorders. Five affective temperaments have been proposed: depressive, cyclothymic, hyperthymic, irritable and anxious. Original instrument for measuring them (TEMPS-A) is a 110-item scale but many short versions in different languages have been validated. The aim of this study was to obtain a short self-administered Spanish version of TEMPS-A with good psychometric properties.

Materials and methods

A sample of 550 students who answered the argentinean version of TEMPS-A was included, after psychometric analysis a comparison between inpatients with major depression and their matched controls by sex and age who answered the brief version was performed to get an external validation.

Results

The sample was composed by 298 (54.2%) women. The mean age was 23.3 year (SD = 6.2). A forced five factor analysis was performed. The 7 items with the highest factorial load (more than 0.350) for each subscale were included in the brief version. The Cronbach alpha's ranged from 0.690 to .800. The most prevalent temperament was hyperthymic followed by cyclothymic for students sample. Similarities between students and controls sample were observed, but not with patients with major depression.

Conclusions

This brief Spanish version of TEMPS-A (35 items) has good psychometric properties and can be used in general and clinical population.
引言识别情绪气质既有助于了解普通人群的正常行为变化,也有助于确定临床上是否存在某些疾病的易感性。目前已提出了五种情绪气质:抑郁型、周期性抑郁型、亢进型、易怒型和焦虑型。最初的测量工具(TEMPS-A)包含 110 个项目,但已有许多不同语言的简短版本通过验证。本研究的目的是获得一个具有良好心理测量特性的简短的西班牙文版 TEMPS-A:在对重度抑郁症住院患者进行心理测量分析后,将他们与回答简短版 TEMPS-A 的性别和年龄相匹配的对照组进行比较,以获得外部验证:样本中有 298 名女性(54.2%)。平均年龄为 23.3 岁(SD=6.2)。进行了强制五因子分析。每个分量表中因子载荷最高(大于 0.350)的 7 个项目被纳入简明版。Cronbach alpha 在 0.690 到 0.800 之间。在学生样本中,最常见的气质是多愁善感型,其次是周期性多愁善感型。学生与对照组样本之间存在相似性,但与重度抑郁症患者之间不存在相似性:西班牙文简明版 TEMPS-A(35 个项目)具有良好的心理测量特性,可用于普通人群和临床人群。
{"title":"Validation study of the Spanish brief version of TEMPS-A","authors":"Jessica Zapata-Téllez ,&nbsp;Hiram Ortega-Ortiz ,&nbsp;Lizette Quiroz-Casián ,&nbsp;Claudia Becerra-Palars ,&nbsp;María del Carmen Elizabeth Lara-Muñoz ,&nbsp;Gustavo H. Vázquez","doi":"10.1016/j.rpsm.2021.08.002","DOIUrl":"10.1016/j.rpsm.2021.08.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Identifying affective temperaments could be useful both for understanding the normal behavioral variations in the general population and to establish if there is a clinical predisposition to certain disorders. Five affective temperaments have been proposed: depressive, cyclothymic, hyperthymic, irritable and anxious. Original instrument for measuring them (TEMPS-A) is a 110-item scale but many short versions in different languages have been validated. The aim of this study was to obtain a short self-administered Spanish version of TEMPS-A with good psychometric properties.</div></div><div><h3>Materials and methods</h3><div>A sample of 550 students who answered the argentinean version of TEMPS-A was included, after psychometric analysis a comparison between inpatients with major depression and their matched controls by sex and age who answered the brief version was performed to get an external validation.</div></div><div><h3>Results</h3><div>The sample was composed by 298 (54.2%) women. The mean age was 23.3 year (<em>SD</em> <!-->=<!--> <!-->6.2). A forced five factor analysis was performed. The 7 items with the highest factorial load (more than 0.350) for each subscale were included in the brief version. The Cronbach alpha's ranged from 0.690 to .800. The most prevalent temperament was hyperthymic followed by cyclothymic for students sample. Similarities between students and controls sample were observed, but not with patients with major depression.</div></div><div><h3>Conclusions</h3><div>This brief Spanish version of TEMPS-A (35 items) has good psychometric properties and can be used in general and clinical population.</div></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 4","pages":"Pages 190-194"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39383254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EMDR therapy vs. supportive therapy as adjunctive treatment in trauma-exposed bipolar patients: A randomised controlled trial EMDR疗法与辅助疗法作为创伤暴露型躁郁症患者的辅助治疗:随机对照试验
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.sjpmh.2023.11.005
Bridget Hogg , Joaquim Radua , Itxaso Gardoki-Souto , Marta Fontana-McNally , Walter Lupo , María Reinares , Esther Jiménez , Mercè Madre , Laura Blanco-Presas , Romina Cortizo , Anna Massó-Rodriguez , Juan Castaño , Isabel Argila , José Ignacio Castro-Rodriguez , Mercè Comes , Cristina Macias , Roberto Sánchez-González , Estanislao Mur-Mila , Patricia Novo , Adriane R. Rosa , Benedikt L. Amann

Introduction

Patients with bipolar disorder (BD) are frequently exposed to traumatic events which worsen disease course, but this study is the first multicentre randomised controlled trial to test the efficacy of a trauma-focused adjunctive psychotherapy in reducing BD affective relapse rates.

Materials and methods

This multicentre randomised controlled trial included 77 patients with BD and current trauma-related symptoms. Participants were randomised to either 20 sessions of trauma-focused Eye Movement Desensitization and Reprocessing (EMDR) therapy for BD, or 20 sessions of supportive therapy (ST). The primary outcome was relapse rates over 24-months, and secondary outcomes were improvements in affective and trauma symptoms, general functioning, and cognitive impairment, assessed at baseline, post-treatment, and at 12- and 24-month follow-up. The trial was registered prior to starting enrolment in clinical trials (NCT02634372) and carried out in accordance with CONSORT guidelines.

Results

There was no significant difference between treatment conditions in terms of relapse rates either with or without hospitalisation. EMDR was significantly superior to ST at the 12-month follow up in terms of reducing depressive symptoms (p = 0.0006, d = 0.969), manic symptoms (p = 0.027, d = 0.513), and improving functioning (p = 0.038, d = 0.486). There was no significant difference in dropout between treatment arms.

Conclusions

Although the primary efficacy criterion was not met in the current study, trauma-focused EMDR was superior to ST in reducing of affective symptoms and improvement of functioning, with benefits maintained at six months following the end of treatment. Both EMDR and ST reduced trauma symptoms as compared to baseline, possibly due to a shared benefit of psychotherapy. Importantly, focusing on traumatic events did not increase relapses or dropouts, suggesting psychological trauma can safely be addressed in a BD population using this protocol.
导言躁郁症(BD)患者经常会遇到创伤事件,这些创伤事件会加重病程,但这项研究是首个多中心随机对照试验,测试了以创伤为重点的辅助心理疗法在降低BD情感复发率方面的疗效。参与者被随机分配接受20次以创伤为重点的眼动脱敏和再加工疗法(EMDR)或20次支持疗法(ST)。主要结果是24个月内的复发率,次要结果是情感和创伤症状、一般功能和认知障碍的改善情况,分别在基线、治疗后、12个月和24个月的随访中进行评估。该试验已在临床试验(NCT02634372)开始注册之前进行了登记,并按照CONSORT指南进行。在为期12个月的随访中,EMDR在减轻抑郁症状(p = 0.0006,d = 0.969)、躁狂症状(p = 0.027,d = 0.513)和改善功能(p = 0.038,d = 0.486)方面明显优于ST。结论虽然本研究未达到主要疗效标准,但以创伤为重点的 EMDR 在减少情感症状和改善功能方面优于 ST,且在治疗结束后的六个月内仍能保持疗效。与基线相比,EMDR和ST都能减少创伤症状,这可能是由于心理治疗的共同优势。重要的是,关注创伤事件并不会增加复发或辍学率,这表明使用该方案可以安全地解决BD人群的心理创伤问题。
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引用次数: 0
Persons first: staying close to the roots of psychiatry 以人为本:贴近精神病学的根源。
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.sjpmh.2024.10.001
Rafael Tabarés-Seisdedos , Vicent Balanzá-Martínez
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引用次数: 0
Spanish validation of the Empirically Developed Clinical Staging Model (EmDe-5) for patients with bipolar disorder 西班牙对双相情感障碍患者经验开发的临床分期模型(EmDe-5)的验证。
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.rpsm.2021.09.005
Lorena de la Fuente-Tomás , Belén Arranz , Pilar Sierra , Mónica Sánchez-Autet , Ana García-Blanco , Luis Gutiérrez-Rojas , Vicent Balanzá-Martínez , Sonia Vidal-Rubio , Eduard Vieta , Esther Jiménez , Carla Hernández , Manuel Arrojo , Jesús Gómez-Trigo , Yolanda Zapico-Merayo , Jose María Pelayo-Terán , Victor Pérez-Solà , Estanislao Mur , Narcís Cardoner , Ana González-Pinto , Iñaki Zorrilla , Maria Paz García-Portilla

Introduction

Bipolar disorder (BD) has been reconceptualised as a progressive disorder that develops from mild to severe presentations. An empirical staging model – the Empirically Developed Clinical Staging Model for BD (EmDe-5) – was developed in a previous study. This study aims to further validate that model using a larger and more representative Spanish sample.

Material and methods

183 BD outpatients were recruited at 11 sites in Spain. Assessment included clinical characteristics of the BD (number of hospitalisations, number of suicide attempts, comorbid personality disorders), physical health (BMI, metabolic syndrome, number of physical illnesses), cognition (SCIP), functioning (permanently disabled due to BD, FAST), and quality of life (SF-36). The CGI-S, VAS-S, and psychopharmacological treatment pattern were used as external validators.

Results

Ten patients (51.5%) were classified as stage 1, 33 (18%) as stage 2, 93 (50 8%) as stage 3, 37 (20 2%) as stage 4, and 10 (5 5%) as stage 5. All profilers, other than number of suicide attempts (p = 0.311) and comorbid personality disorder (p = 0.061), exhibited worse scores from stage 1 to 5. As expected, VAS-S and CGI-S scores were worse in the later stages. Regarding treatment, early stages (1–2) were associated with the use of one to three drugs while late stages (4–5) were associated with four or more drugs (p = 0.002).

Conclusions

We confirm the EmDe-5 staging model's construct validity. The ease of obtaining the profilers, together with the operational criteria provided to quantify them, will facilitate the use of the EmDe-5 staging model in daily clinical practice.
双相情感障碍(BD)已经被重新定义为一种从轻度到重度的进行性疾病。经验分期模型-经验开发的BD临床分期模型(EmDe-5) -在之前的研究中被开发出来。本研究旨在使用更大更有代表性的西班牙样本进一步验证该模型。材料和方法:在西班牙11个地点招募183名BD门诊患者。评估包括双相障碍的临床特征(住院次数、自杀企图次数、共病人格障碍)、身体健康(BMI、代谢综合征、身体疾病数量)、认知(SCIP)、功能(因双相障碍永久残疾、FAST)和生活质量(SF-36)。采用CGI-S、VAS-S和精神药理学治疗模式作为外部验证器。结果:1期10例(51.5%),2期33例(18%),3期93例(508%),4期37例(202%),5期10例(55%)。除自杀企图数(p=0.311)和共病人格障碍(p=0.061)外,所有分析者在第一至第五阶段的得分都较差。正如预期的那样,VAS-S和CGI-S评分在后期较差。关于治疗,早期(1-2)与使用一到三种药物相关,而晚期(4-5)与使用四种或更多种药物相关(p=0.002)。结论:我们证实了EmDe-5分期模型的结构效度。易于获得的分析器,连同提供的操作标准来量化它们,将有助于在日常临床实践中使用EmDe-5分期模型。
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引用次数: 0
Pharmacological treatment for challenging behavior in adults with intellectual disability: Systematic review and meta-analysis 成人智力残疾挑战行为的药理学治疗:系统综述和荟萃分析。
0 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/j.rpsm.2023.01.003
Rodrigo Campos-Jara , Cristian Martínez-Salazar , Christian Campos-Jara , José María Fernández , Darío Martínez-García , Falonn Contreras-Osorio

Introduction

Few evidence on the use of antipsychotics in people with intellectual disabilities and challenging behaviors, generates the need to develop studies that contribute to collect, compare and synthesize the available information. The present systematic review and meta-analysis aims to determine the clinical efficacy of antipsychotic medication in reducing critical episodes in this population.

Methods

We searched Web of Science, Scopus, EBSCO, Embase, and PubMed for randomized controlled trials of antipsychotic medication versus placebo. Preliminarily yielded 1354 abstracts and citations; six studies with 274 subjects met the inclusion criteria of studies with experimental design, longitudinal type, with pre- and post-intervention measurements.

Results

There is evidence for the use of psychotropic drugs in the acute management of challenging behaviors in patients with intellectual disability (SMD = −0.85; 95% CI = −1.69 to −0.01; p = 0.05).

Conclusions

Our results coincide with the recommendations on the efficacy of the use of antipsychotics. Although our study provides evidence, the limited number of studies included in this research does not allow us to obtain totally conclusive results, although it can be considered as a guide for future studies.
引言:关于在智障和有挑战性行为的人中使用抗精神病药物的证据很少,因此需要开展有助于收集、比较和综合现有信息的研究。本系统综述和荟萃分析旨在确定抗精神病药物在减少该人群危重发作方面的临床疗效。方法:我们在Web of Science、Scopus、EBSCO、Embase和PubMed上搜索抗精神病药物与安慰剂的随机对照试验。初步产生1354篇摘要和引文;6项涉及274名受试者的研究符合实验设计、纵向类型、干预前后测量的纳入标准。结果:有证据表明精神药物用于智力残疾患者挑战行为的急性管理(SMD=-0.85;95%CI=1.69-0.01;p=0.05)。结论:我们的结果与关于使用抗精神病药物疗效的建议一致。尽管我们的研究提供了证据,但这项研究中包含的研究数量有限,无法使我们获得完全结论性的结果,尽管它可以被视为未来研究的指南。
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引用次数: 0
期刊
Spanish Journal of Psychiatry and Mental Health
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