Pub Date : 2024-04-20DOI: 10.1016/j.soda.2024.100140
Francisco J. Morera Ocon , Antonio Prat Calero , Luis E. Lopez Calderon , Francisco Landete Molina
Background
Herein we describe the anatomic consequences of maintaining splenic artery and removing the splenic vein in distal pancreatectomy with spleen preservation.
Patients and Methods
The records of 9 patients who were scheduled for splenic preservation distal pancreatectomy were analyzed.
Results
Three patients underwent vessels preservation, 4 had splenic vein ligation and artery preservation, Warshaw procedure was performed in 1 patient, and another patient required unintended splenectomy. In the long-term follow-up, one patient had submucosal gastric varices and gastrointestinal bleeding 12.7 years after distal pancreatectomy. One patient developed perisplenic varicesand hypertrophic perigastric veins, and 3 patients developed perigastric hypertrophic vessels. None of these patients manifest gastric bleeding.
Discussion
Spleen preservation in distal pancreatectomy can be performed by preserving splenic artery and vein, ligation of the vein, or ligation of vein and artery and preservation of short gastric vessels. It is not unusual the hypertrophic perigastric vessels development after distal pancreatectomy with spleen preservation. Submucosal varices may result in late gastric hemorrhage.
{"title":"Surgical strategies for spleen preserving distal pancreatectomy and its consequences in perigastric vascularization","authors":"Francisco J. Morera Ocon , Antonio Prat Calero , Luis E. Lopez Calderon , Francisco Landete Molina","doi":"10.1016/j.soda.2024.100140","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100140","url":null,"abstract":"<div><h3>Background</h3><p>Herein we describe the anatomic consequences of maintaining splenic artery and removing the splenic vein in distal pancreatectomy with spleen preservation.</p></div><div><h3>Patients and Methods</h3><p>The records of 9 patients who were scheduled for splenic preservation distal pancreatectomy were analyzed.</p></div><div><h3>Results</h3><p>Three patients underwent vessels preservation, 4 had splenic vein ligation and artery preservation, Warshaw procedure was performed in 1 patient, and another patient required unintended splenectomy. In the long-term follow-up, one patient had submucosal gastric varices and gastrointestinal bleeding 12.7 years after distal pancreatectomy. One patient developed perisplenic varicesand hypertrophic perigastric veins, and 3 patients developed perigastric hypertrophic vessels. None of these patients manifest gastric bleeding.</p></div><div><h3>Discussion</h3><p>Spleen preservation in distal pancreatectomy can be performed by preserving splenic artery and vein, ligation of the vein, or ligation of vein and artery and preservation of short gastric vessels. It is not unusual the hypertrophic perigastric vessels development after distal pancreatectomy with spleen preservation. Submucosal varices may result in late gastric hemorrhage.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100140"},"PeriodicalIF":0.0,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000144/pdfft?md5=4d36a8931b1d610083dc4bd674256a62&pid=1-s2.0-S2667008924000144-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140621038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.1016/j.soda.2024.100144
Francesco Esposito, Dorin Sacrieru, Nouredine Meziani, Marco Del Prete, Morad Kabbej
Background
During laparoscopic inguinal hernia repair (LIH) repair, it is common practice to insert a urinary catheter (UC) to mitigate the risk of bladder injury or acute postoperative urinary retention. However, this procedure often leads to potential complications or infections. This study aims to evaluate the implications of the UC placement during LIH repair.
Methods
This retrospective, monocentric study included patients who underwent LIH repair between 01/01/2018 to 31/12/2022. Patients were divided into two groups: UC and no-UC.
Results
212 patients were included: 119 (56 %) in the no-UC group and 93 (44 %) in the UC group. The UC group presented a higher prevalence of bilateral hernias (38.7 % vs. 52.7 %), (p=0.01) and a greater frequency of intraperitoneal approach (TAPP) (83.9 % vs. 100 %), (p=0.01). No intraoperative complications were attributable to the absence of the UC. Four patients in the UC group had postoperative acute urinary retention necessitating intermittent catheterization, allowing discharge (p = 0.13). Rates of readmission and reoperation rates were comparable between groups. One month post-surgery, 7.5 % of UC group patients (vs. 0.8 %) developed urinary tract infection (p=0.01). Subgroup analysis confirmed a higher incidence of urinary tract infections in unilateral hernia and in TAPP procedure.
Conclusion
Routine UC insertion during LIH repair seems unnecessary; rather, it increases the risk of postoperative urinary tract infections and should thus be avoided.
{"title":"Urinary catheterization during laparoscopic inguinal hernia repair: Really necessary or a habit?","authors":"Francesco Esposito, Dorin Sacrieru, Nouredine Meziani, Marco Del Prete, Morad Kabbej","doi":"10.1016/j.soda.2024.100144","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100144","url":null,"abstract":"<div><h3>Background</h3><p>During laparoscopic inguinal hernia repair (LIH) repair, it is common practice to insert a urinary catheter (UC) to mitigate the risk of bladder injury or acute postoperative urinary retention. However, this procedure often leads to potential complications or infections. This study aims to evaluate the implications of the UC placement during LIH repair.</p></div><div><h3>Methods</h3><p>This retrospective, monocentric study included patients who underwent LIH repair between 01/01/2018 to 31/12/2022. Patients were divided into two groups: UC and no-UC.</p></div><div><h3>Results</h3><p>212 patients were included: 119 (56 %) in the no-UC group and 93 (44 %) in the UC group. The UC group presented a higher prevalence of bilateral hernias (38.7 % vs. 52.7 %), (<em>p</em> <em>=</em> <em>0.01</em>) and a greater frequency of intraperitoneal approach (TAPP) (83.9 % vs. 100 %), (<em>p</em> <em>=</em> <em>0.01</em>). No intraoperative complications were attributable to the absence of the UC. Four patients in the UC group had postoperative acute urinary retention necessitating intermittent catheterization, allowing discharge (<em>p</em> = 0.13). Rates of readmission and reoperation rates were comparable between groups. One month post-surgery, 7.5 % of UC group patients (vs. 0.8 %) developed urinary tract infection (<em>p</em> <em>=</em> <em>0.01</em>). Subgroup analysis confirmed a higher incidence of urinary tract infections in unilateral hernia and in TAPP procedure.</p></div><div><h3>Conclusion</h3><p>Routine UC insertion during LIH repair seems unnecessary; rather, it increases the risk of postoperative urinary tract infections and should thus be avoided.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100144"},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000181/pdfft?md5=c97a92374f980ee82c56e78193554f17&pid=1-s2.0-S2667008924000181-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140557793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
External rectal prolapse (ERP) is a complete protrusion of the rectal wall through the anal canal. The precise prevalence of recurrent (R)- ERP is still unknown although some studies have reported 20–30 % after primary surgery. The aim of this study was to assess the anatomic and functional outcomes of R-ERP surgical treatment proposing a decision-making algorithm for this rare and challenging disease.
Material and methods
This is a case series report. Of the 141 patients treated for external rectal prolapsed between January 2014 and December 2020, 19 (3M-16F) developed a recurrence. Anatomical recurrence was assessed and classified as complete or partial and mucosal or full-thickness. Functional outcomes were assessed using Wexner scores for constipation and incontinence. The global satisfaction rate was evaluated using a 5-point scale.
Results
The patients were stratified according to the first line surgery: 5(26 %) Delorme (Group A), 6(32 %) Altemeier (Group B), and 8(42 %) robotic ventral rectopexy (Group C). Five patients had a previous proctologic and pelvic floor surgery; Functional disorders were: 8 (42 %) fecal incontinence and 4(21 %) ODS. The overall recurrence rate was 21.4 %. The overall functional outcomes showed a significant improvement in the Wexner incontinence score (median value 8.7 vs 3.1) and constipation score (10.4 vs 4.6). 78.6 % patients declared to be satisfied.
Conclusion
The treatment of choice for R-ERP needs to be tailored according to personal surgical competence considering the first-line ERP surgery,prolapse characteristics, and patients’ comorbidities.
{"title":"Management of recurrent external rectal prolapse. A single center experience","authors":"Alessandro Sturiale, Lisa Fralleone, Bernardina Fabiani, Claudia Menconi, Vittorio d'Adamo, Gabriele Naldini","doi":"10.1016/j.soda.2024.100137","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100137","url":null,"abstract":"<div><h3>Introduction</h3><p>External rectal prolapse (ERP) is a complete protrusion of the rectal wall through the anal canal. The precise prevalence of recurrent (<em>R</em>)- ERP is still unknown although some studies have reported 20–30 % after primary surgery. The aim of this study was to assess the anatomic and functional outcomes of R-ERP surgical treatment proposing a decision-making algorithm for this rare and challenging disease.</p></div><div><h3>Material and methods</h3><p>This is a case series report. Of the 141 patients treated for external rectal prolapsed between January 2014 and December 2020, 19 (3M-16F) developed a recurrence. Anatomical recurrence was assessed and classified as complete or partial and mucosal or full-thickness. Functional outcomes were assessed using Wexner scores for constipation and incontinence. The global satisfaction rate was evaluated using a 5-point scale.</p></div><div><h3>Results</h3><p>The patients were stratified according to the first line surgery: 5(26 %) Delorme (Group A), 6(32 %) Altemeier (Group B), and 8(42 %) robotic ventral rectopexy (Group C). Five patients had a previous proctologic and pelvic floor surgery; Functional disorders were: 8 (42 %) fecal incontinence and 4(21 %) ODS. The overall recurrence rate was 21.4 %. The overall functional outcomes showed a significant improvement in the Wexner incontinence score (median value 8.7 vs 3.1) and constipation score (10.4 vs 4.6). 78.6 % patients declared to be satisfied.</p></div><div><h3>Conclusion</h3><p>The treatment of choice for R-ERP needs to be tailored according to personal surgical competence considering the first-line ERP surgery,prolapse characteristics, and patients’ comorbidities.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100137"},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000119/pdfft?md5=04eaff135d4e8cfaa0407b5ab51f8426&pid=1-s2.0-S2667008924000119-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140343931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.soda.2024.100136
Mohammad Rida Farhat , Zahraa H. Moussawi , Mariam Hijazi , Anis Husset
Background
Gastric cancer is an important cause of morbidity and mortality worldwide. Laparoscopic procedures have been adopted to perform oncologic resection but still required a mini-laparotomy incision for specimen extraction. Natural orifice specimen extraction has proven to be an effective method to minimize trauma, decrease complications, speed recovery, and improve cosmetic result.
Case presentation
This is the case of a 67-year-old obese lady presenting with asymptomatic microcytic anemia wherein investigations revealed her to have subcardial gastric adenocarcinoma stage IIA. She underwent neoadjuvant chemotherapy followed by laparoscopic total gastrectomy with D2 lymphadenectomy. The procedure was complemented by a roux-en-y gastrojejunal anastomosis complemented with transvaginal specimen extraction through a posterior colpotomy. The recovery period post-operatively went smoothly and the patient had no major complaints on follow up.
Conclusion
Extracting a gastric cancer specimen transvaginally after laparoscopic procedures is feasible in females, mostly postmenopausal, who are overweight, even obese, and might pose a way to lessen complications post-operatively.
{"title":"Totally laparoscopic total gastrectomy with transvaginal specimen extraction in obese female patient: A case report","authors":"Mohammad Rida Farhat , Zahraa H. Moussawi , Mariam Hijazi , Anis Husset","doi":"10.1016/j.soda.2024.100136","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100136","url":null,"abstract":"<div><h3>Background</h3><p>Gastric cancer is an important cause of morbidity and mortality worldwide. Laparoscopic procedures have been adopted to perform oncologic resection but still required a mini-laparotomy incision for specimen extraction. Natural orifice specimen extraction has proven to be an effective method to minimize trauma, decrease complications, speed recovery, and improve cosmetic result.</p></div><div><h3>Case presentation</h3><p>This is the case of a 67-year-old obese lady presenting with asymptomatic microcytic anemia wherein investigations revealed her to have subcardial gastric adenocarcinoma stage IIA. She underwent neoadjuvant chemotherapy followed by laparoscopic total gastrectomy with D2 lymphadenectomy. The procedure was complemented by a roux-en-y gastrojejunal anastomosis complemented with transvaginal specimen extraction through a posterior colpotomy. The recovery period post-operatively went smoothly and the patient had no major complaints on follow up.</p></div><div><h3>Conclusion</h3><p>Extracting a gastric cancer specimen transvaginally after laparoscopic procedures is feasible in females, mostly postmenopausal, who are overweight, even obese, and might pose a way to lessen complications post-operatively.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"13 ","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000107/pdfft?md5=1ff68001676f31e37b9f1d90ef0cd5d8&pid=1-s2.0-S2667008924000107-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140347896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.soda.2024.100131
Guillaume Meurette MD PhD (Guest editor for the Special issue “New advances in Proctology”)
{"title":"New advances in Proctology","authors":"Guillaume Meurette MD PhD (Guest editor for the Special issue “New advances in Proctology”)","doi":"10.1016/j.soda.2024.100131","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100131","url":null,"abstract":"","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"13 ","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000053/pdfft?md5=4f57e6d105bac84922e655262b1a3588&pid=1-s2.0-S2667008924000053-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140546053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-29DOI: 10.1016/j.soda.2024.100135
Rana Ibrahim , Abbas Fadel , Layal Ahmad , Hajar Ballout , Houssein Haidar Ahmad
Background
Obesity management presents a persistent challenge. Bariatric surgery, recognized for its transformative impact on weight loss and comorbidities, demands a thorough examination of its long-term implications.
Objectives
Our goal is to investigate different aspects of bariatric surgery, such as complications, comorbidities, infection rates, the long-term sustainability of weight loss, and factors predicting weight loss over an extended period following the procedure.
Setting
This study involves 100 patients who underwent primary bariatric surgery.
Methods
a sophisticated Longitudinal Observational Study design. With a Retrospective Component and a Follow-Up Component spanning eight years.
Results
The study included participants with a mean age of 36.4 years (±12.1) and a pre-surgery BMI of 44.5 kg/m² (±7.5). Excess Weight Loss (%EWL) peaked at 75.09 % by the third year, while Total Weight Loss (%TWL) sustained at 33.41 % after two years. Among individuals with type 2 diabetes, medication discontinuation rates reached 26.3 % at 5 years. Zero leaks, a low incidence of major complications and no incidence of mortality have been noted. In an extended 7-year follow-up, 40 % of patients experienced weight regain. Multivariate analyses identified age and preoperative BMI as negatively associated significant predictors impacting %EWL at three years, with standardized beta coefficients of −0.488 (p = 0.001) and −0.450 (p < 0.001), respectively. Conversely, smoking and Type 2 Diabetes Mellitus exhibited positive associations, with standardized beta coefficients of 0.336 (p = 0.004) and 0.286 (p = 0.063), respectively.
Conclusions
Bariatric surgery is acknowledged as a safe and efficacy procedure for reducing weight and comorbidities, with a relatively low incidence of major complications.
{"title":"Long-term outcomes of bariatric surgery: An eight-year study at a tertiary care hospital in Lebanon","authors":"Rana Ibrahim , Abbas Fadel , Layal Ahmad , Hajar Ballout , Houssein Haidar Ahmad","doi":"10.1016/j.soda.2024.100135","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100135","url":null,"abstract":"<div><h3>Background</h3><p>Obesity management presents a persistent challenge. Bariatric surgery, recognized for its transformative impact on weight loss and comorbidities, demands a thorough examination of its long-term implications.</p></div><div><h3>Objectives</h3><p>Our goal is to investigate different aspects of bariatric surgery, such as complications, comorbidities, infection rates, the long-term sustainability of weight loss, and factors predicting weight loss over an extended period following the procedure.</p></div><div><h3>Setting</h3><p>This study involves 100 patients who underwent primary bariatric surgery.</p></div><div><h3>Methods</h3><p>a sophisticated Longitudinal Observational Study design. With a Retrospective Component and a Follow-Up Component spanning eight years.</p></div><div><h3>Results</h3><p>The study included participants with a mean age of 36.4 years (±12.1) and a pre-surgery BMI of 44.5 kg/m² (±7.5). Excess Weight Loss (%EWL) peaked at 75.09 % by the third year, while Total Weight Loss (%TWL) sustained at 33.41 % after two years. Among individuals with type 2 diabetes, medication discontinuation rates reached 26.3 % at 5 years. Zero leaks, a low incidence of major complications and no incidence of mortality have been noted. In an extended 7-year follow-up, 40 % of patients experienced weight regain. Multivariate analyses identified age and preoperative BMI as negatively associated significant predictors impacting %EWL at three years, with standardized beta coefficients of −0.488 (<em>p</em> = 0.001) and −0.450 (<em>p</em> < 0.001), respectively. Conversely, smoking and Type 2 Diabetes Mellitus exhibited positive associations, with standardized beta coefficients of 0.336 (<em>p</em> = 0.004) and 0.286 (<em>p</em> = 0.063), respectively.</p></div><div><h3>Conclusions</h3><p>Bariatric surgery is acknowledged as a safe and efficacy procedure for reducing weight and comorbidities, with a relatively low incidence of major complications.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100135"},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000090/pdfft?md5=e5e521b72d3393bb97209c34a401c3a0&pid=1-s2.0-S2667008924000090-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140328630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-13DOI: 10.1016/j.soda.2024.100132
Maxime Nguyen , Nathan Moreno-Lopez , Abderrahmane Bourredjem , Damien Leleu , Jean-Paul Pais de Barros , Kevin Van-Dongen , Isabelle Fournel , Mathieu Blot , David Masson , Thomas Gautier , Pablo Ortega-Deballon
Background
Perioperative inflammation is a predictor of surgical complications and cancer prognosis in surgical oncology. Multimodal protocols are ongoing in order to find ways to control inflammation. A preoperative flash high-dose of corticosteroids has been suggested as a way to control perioperative inflammation, but its safety in colorectal surgery needs to be established prior to a phase 3 trial. The physiologic effects of such a dose should also be explored.
Methods
Prospective bicentric phase 2 single-arm study with a biological ancillary study. Patients were administered 20 mg/kg of methyl-prednisone before colorectal surgery. Primary outcome was major post-operative complications defined as a grade >II according to the Dindo-Clavien classification. Ancillary outcome was plasma endotoxin concentration and activity.
Results
Sixty-seven patients were included. Twelve (17.9 % [90 %CI:10.9 %-29.6 %]) patients developed major post-operative complications. No homeostatic disturbances troubles were observed. Severe postoperative hyperglycemia concerned 3 (4 %) patients which were all non-diabetic. The concentrations of endotoxin (mass) and its activity lowered between the pre-operative time point and the day after surgery.
Conclusion
Pre-operative single flash of high dose methylprednisolone (20 mg/kg) before elective colorectal surgery seemed safe. Our results suggest that corticosteroids could promote gut barrier integrity, reducing endotoxemia in patients with colorectal surgery. Further studies (in particular a large randomized controlled trial) are needed to confirm our findings and explore a potential benefit of corticosteroid in this population.
{"title":"Evaluation of pre-operative high dose corticosteroids in elective colorectal surgery and effects on gut barrier function: A phase 2 clinical trial","authors":"Maxime Nguyen , Nathan Moreno-Lopez , Abderrahmane Bourredjem , Damien Leleu , Jean-Paul Pais de Barros , Kevin Van-Dongen , Isabelle Fournel , Mathieu Blot , David Masson , Thomas Gautier , Pablo Ortega-Deballon","doi":"10.1016/j.soda.2024.100132","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100132","url":null,"abstract":"<div><h3>Background</h3><p>Perioperative inflammation is a predictor of surgical complications and cancer prognosis in surgical oncology. Multimodal protocols are ongoing in order to find ways to control inflammation. A preoperative flash high-dose of corticosteroids has been suggested as a way to control perioperative inflammation, but its safety in colorectal surgery needs to be established prior to a phase 3 trial. The physiologic effects of such a dose should also be explored.</p></div><div><h3>Methods</h3><p>Prospective bicentric phase 2 single-arm study with a biological ancillary study. Patients were administered 20 mg/kg of methyl-prednisone before colorectal surgery. Primary outcome was major post-operative complications defined as a grade >II according to the Dindo-Clavien classification. Ancillary outcome was plasma endotoxin concentration and activity.</p></div><div><h3>Results</h3><p>Sixty-seven patients were included. Twelve (17.9 % [90 %CI:10.9 %-29.6 %]) patients developed major post-operative complications. No homeostatic disturbances troubles were observed. Severe postoperative hyperglycemia concerned 3 (4 %) patients which were all non-diabetic. The concentrations of endotoxin (mass) and its activity lowered between the pre-operative time point and the day after surgery.</p></div><div><h3>Conclusion</h3><p>Pre-operative single flash of high dose methylprednisolone (20 mg/kg) before elective colorectal surgery seemed safe. Our results suggest that corticosteroids could promote gut barrier integrity, reducing endotoxemia in patients with colorectal surgery. Further studies (in particular a large randomized controlled trial) are needed to confirm our findings and explore a potential benefit of corticosteroid in this population.</p></div><div><h3>ClinicalTrials.gov</h3><p>03437746</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000065/pdfft?md5=7426a08a80b055c2efaa215e6a3fb667&pid=1-s2.0-S2667008924000065-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-13DOI: 10.1016/j.soda.2024.100133
Mohammad Rida Farhat , Mariam Hijazi , Zahraa H. Moussawi , Waed A. Zein , Anis Husset
Background
The surgical trend nowadays is in favor of minimally invasive procedures, particularly for complicated surgeries such as colectomies that require large incisions. Even laparoscopic colectomies still need mini-laparotomy for specimen extraction. Natural orifice specimen extraction (NOSE) has emerged as a way to avoid such incisions and decrease postoperative complications.
Case Presentation
We present two cases of middle-aged ladies that underwent laparoscopic colectomies with NOSE. The first patient presented for recurrent flare-ups of Crohn's refractory to medical treatment with a history of ileocecectomy ending up in anastomotic stenosis at the level of the terminal ileum. Laparoscopic right hemicolectomy was performed with transvaginal specimen extraction through a posterior colpotomy. The second patient underwent a laparoscopic subtotal colectomy for two stenotic lesions of the transverse and left colon. however, in this case, the specimen was extracted transvaginally through an anterior colpotomy. The postoperative hospital stay for both patients was uneventful and neither patient developed any complications related to the site of extraction.
Conclusion
Laparoscopic colectomies with NOSE have a better outcome than traditional ones still requiring abdominal incisions. Following laparoscopic colectomies with transvaginal extraction can be accomplished when patient criteria and surgeon skills allow it. More studies are needed to evaluate the criteria making patients candidates for such procedures and to predict possible postoperative complications.
{"title":"Two cases of laparoscopic right colectomy and laparoscopic subtotal colectomy with transvaginal extraction in two different approaches: A report of two cases","authors":"Mohammad Rida Farhat , Mariam Hijazi , Zahraa H. Moussawi , Waed A. Zein , Anis Husset","doi":"10.1016/j.soda.2024.100133","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100133","url":null,"abstract":"<div><h3>Background</h3><p>The surgical trend nowadays is in favor of minimally invasive procedures, particularly for complicated surgeries such as colectomies that require large incisions. Even laparoscopic colectomies still need mini-laparotomy for specimen extraction. Natural orifice specimen extraction (NOSE) has emerged as a way to avoid such incisions and decrease postoperative complications.</p></div><div><h3>Case Presentation</h3><p>We present two cases of middle-aged ladies that underwent laparoscopic colectomies with NOSE. The first patient presented for recurrent flare-ups of Crohn's refractory to medical treatment with a history of ileocecectomy ending up in anastomotic stenosis at the level of the terminal ileum. Laparoscopic right hemicolectomy was performed with transvaginal specimen extraction through a posterior colpotomy. The second patient underwent a laparoscopic subtotal colectomy for two stenotic lesions of the transverse and left colon. however, in this case, the specimen was extracted transvaginally through an anterior colpotomy. The postoperative hospital stay for both patients was uneventful and neither patient developed any complications related to the site of extraction.</p></div><div><h3>Conclusion</h3><p>Laparoscopic colectomies with NOSE have a better outcome than traditional ones still requiring abdominal incisions. Following laparoscopic colectomies with transvaginal extraction can be accomplished when patient criteria and surgeon skills allow it. More studies are needed to evaluate the criteria making patients candidates for such procedures and to predict possible postoperative complications.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"14 ","pages":"Article 100133"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000077/pdfft?md5=7398c04b4325effadeb4f6ea22ffaacf&pid=1-s2.0-S2667008924000077-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-19DOI: 10.1016/j.soda.2024.100127
Philippe Pouvreau , Thomas Bouyer , Pacome Fosse , Christine Casa , Germain Brehier , Jean-Philippe Lemoine , Geoffrey Urbanski , Christophe Aubé , Anita Paisant
Incidental splenic lesions are common in daily practice and managing them presents challenges. There are no typical imaging features for splenic lesions and the non-invasive diagnosis includes clinical, radiological, and biological evaluation. Most studies published to date propose non-invasive diagnosis algorithms based on imaging features, but often with insufficient specificity. The aim of the present article is to propose an algorithm adapted to the management of all splenic incidentalomas, leading to a final and accurate diagnosis.
The management of splenic incidentaloma should be based on a multimodal approach including benign imaging features, nuclear medicine, follow-up, and biopsy.
{"title":"Management of splenic incidentalomas, a new evidence-based algorithm","authors":"Philippe Pouvreau , Thomas Bouyer , Pacome Fosse , Christine Casa , Germain Brehier , Jean-Philippe Lemoine , Geoffrey Urbanski , Christophe Aubé , Anita Paisant","doi":"10.1016/j.soda.2024.100127","DOIUrl":"https://doi.org/10.1016/j.soda.2024.100127","url":null,"abstract":"<div><p>Incidental splenic lesions are common in daily practice and managing them presents challenges. There are no typical imaging features for splenic lesions and the non-invasive diagnosis includes clinical, radiological, and biological evaluation. Most studies published to date propose non-invasive diagnosis algorithms based on imaging features, but often with insufficient specificity. The aim of the present article is to propose an algorithm adapted to the management of all splenic incidentalomas, leading to a final and accurate diagnosis.</p><p>The management of splenic incidentaloma should be based on a multimodal approach including benign imaging features, nuclear medicine, follow-up, and biopsy.</p></div>","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"13 ","pages":"Article 100127"},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008924000016/pdfft?md5=39b4b246f45a3f83286ed9a0870fbec7&pid=1-s2.0-S2667008924000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-17DOI: 10.1016/j.soda.2023.100119
Tulio Brasileiro Silva Pacheco, Gregory Zielinski, Amir H. Sohail, Jun Levine
{"title":"From sleeve to SubTotal gastrectomy—A complex journey of persistent marginal ulcers and recurrent intervention","authors":"Tulio Brasileiro Silva Pacheco, Gregory Zielinski, Amir H. Sohail, Jun Levine","doi":"10.1016/j.soda.2023.100119","DOIUrl":"https://doi.org/10.1016/j.soda.2023.100119","url":null,"abstract":"","PeriodicalId":101190,"journal":{"name":"Surgery Open Digestive Advance","volume":"13 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667008923000411/pdfft?md5=a1cdeb8d1bbdbaaffe0765b54576fdbb&pid=1-s2.0-S2667008923000411-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}