The Asia Pacific Heart Journal最新文献

英文中文

Forthcoming events 即将到来的事件

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90068-4

引用次数: 0

The National Heart Foundation of Australia: The first 21 years 澳大利亚国家心脏基金会:前21年

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90055-6

Ralph Reader CMG, PAD, FRACP (Medical Director 1961–1970, Director 1970–1980, National Heart Foundation)

The treatment of cardiovascular disease has been one of the late 20th century's great success stories. Rising death rates in Australia in the 1940s and 1950s gave impetus to the movement for the establishment of a community-based heart foundation in Australia, an organisation that could marshal resources and provide leadership to the community in its fight against what appeared to be an epidemic. The new organisation, named the National Heart Foundation, became a reality in 1959, the third such community-based heart foundation to be formed worldwide. The hard work and vision of interested, community-minded citizens and members of the medical profession, together with the support of the Federal Government and the press, resulted in a highly successful initial appeal for funds in 1961. Following further appeals in 1969 and 1975, an annual fund-raising program was adopted and financial resources allocated on the basis of merit, to scientific and medical research programs. Other major projects initiated by the Foundation in the 1960s and 1970s included: the Australian Therapeutic Trial in Mild Hypertension; the collection of data on the extent and nature of disease (including a register of heart attack for the city of Perth in 1971–1972, and a register of cardiac surgery for Australia); and education and rehabilitation programs.

心血管疾病的治疗是20世纪末最伟大的成功故事之一。20世纪40年代和50年代，澳大利亚的死亡率不断上升，这推动了在澳大利亚建立一个以社区为基础的心脏病基金会的运动，这个组织可以调动资源，并在与似乎是流行病的疾病的斗争中为社区提供领导。这个名为“国家心脏基金会”的新组织于1959年成立，是世界上第三个以社区为基础的心脏基金会。有兴趣的、有社区意识的公民和医疗专业人员的辛勤工作和远见卓识，加上联邦政府和新闻界的支持，使1961年的初步筹资呼吁非常成功。在1969年和1975年的进一步呼吁之后，通过了一项年度筹款方案，并根据成绩将财政资源分配给科学和医学研究项目。基金会在20世纪60年代和70年代发起的其他重大项目包括:澳大利亚轻度高血压治疗试验;收集关于疾病程度和性质的数据(包括1971-1972年珀斯市心脏病发作登记和澳大利亚心脏手术登记);以及教育和康复项目。

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引用次数: 0

Cardiovascular health in Australia: Current state and future directions 澳大利亚的心血管健康:现状和未来方向

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90060-X

A. Tonkin, A. Bauman, S. Bennett, A. Dobson, G. Hankey, I. Ring

引用次数: 4

National heart foundation: A new millennium initiative — where could new dollars go? 国家心脏基金会:一个新的千禧年倡议-新的资金可以去哪里?

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90059-3

L. Beilin

引用次数: 0

Textbook of interventional cardiology 介入心脏病学教科书

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90061-1

David Brieger

引用次数: 83

The National Heart Foundation's research program 国家心脏基金会的研究项目

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90058-1

Philip Barter PHD, MRACP, FRACR (Chair, National Heart Foundation Research Committee)

The National Heart Foundation of Australia has been supporting cardiovascular research for more than 40 years. It has funded grants-in-aid to a wide range of researchers involved in basic, clinical and public health aspects of cardiovascular disease. It has also provided salary support for a large number of scholarships and fellowships. In addition, it has initiated and conducted projects of its own in the areas of epidemiology and public health research and, in partnership with industrial sponsors, has conducted large-scale clinical trials.[a/b]

澳大利亚国家心脏基金会40多年来一直支持心血管研究。它为涉及心血管疾病基础、临床和公共卫生方面的广泛研究人员提供了资助。它还为大量奖学金和研究金提供薪金支助。此外，它还在流行病学和公共卫生研究领域发起和开展了自己的项目，并与工业赞助者合作进行了大规模临床试验。

引用次数: 0

Royal Australasian College of surgeons annual sciuentific congress ASC 2000 2000年澳大利亚皇家外科医师学会年度科学大会

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90066-0

引用次数: 0

The 40th anniversary of the heart foundation of Australia 澳大利亚心脏基金会成立40周年

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90054-4

Franklin Rosenfeldt (Editor-in-Chief)

引用次数: 0

Glucose, insulin, potassium (GIK) and the concept of metabolic support for the postischaemic heart 葡萄糖，胰岛素，钾(GIK)和脑缺血后心脏代谢支持的概念

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90052-0

Frank Laws MD, Heinrich Taegtmeyer MD, DPhil

Successful reperfusion has moved the frontier of treatment for acute myocardial ischaemia from coronary arteries to the heart muscle itself. Here we update the concept of metabolic support for the postischaemic heart which is based on an understanding of an earlier review on the same topic. The ischaemic heart is an energy-depleted organ. A mismatch of ATP production and utilisation leads to the uncoupling of ATP-dependent Ca²⁺-mediated excitation-contraction coupling necessary for normal contractile function. Sustained ischaemia leads to adaptive changes of either programed cell survival, cell death or cell necrosis. We are presenting a working hypothesis on the metabolic and ionic consequences of myocardial ischaemia that lead to progressive contractile dysfunction. Based on this hypothesis we develop a rationale for the use of GIK in the support of substrate metabolism by replenishing depleted energy stores to reverse the deleterious events in the postischaemic state. Possible mechanisms include replenishment of depleted cellular glycogen stores and restoration of efficient energy transfer through moiety-conserved cycles. The usefulness of this concept has been demonstrated in the improved survival of patients in cardiogenic shock after hypothermic ischaemic arrest of the heart and in patients with acute myocardial infarction treated with GIK.

成功的再灌注已经将治疗急性心肌缺血的前沿从冠状动脉转移到心肌本身。在这里，我们更新了缺血性心脏代谢支持的概念，这是基于对同一主题的早期综述的理解。缺血的心脏是一个能量耗尽的器官。ATP生产和利用的不匹配导致ATP依赖的Ca2+介导的兴奋-收缩耦联解偶联，这是正常收缩功能所必需的。持续缺血可导致程序性细胞存活、细胞死亡或细胞坏死的适应性变化。我们提出了一个关于心肌缺血导致进行性收缩功能障碍的代谢和离子后果的工作假设。基于这一假设，我们提出了使用GIK的基本原理，通过补充耗尽的能量储存来支持底物代谢，以逆转缺血后状态的有害事件。可能的机制包括补充耗尽的细胞糖原储存和通过能量守恒循环恢复有效的能量转移。这一概念的有效性已在心脏低温缺血停搏后心源性休克患者和急性心肌梗死患者接受GIK治疗后的生存率提高中得到证明。

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引用次数: 0

Textbook of interventional cardiology 介入心脏病学教科书

The Asia Pacific Heart Journal

Pub Date : 1999-12-01 DOI: 10.1016/S1328-0163(99)90061-1

D. Brieger

引用次数: 91

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