The Asia Pacific Heart Journal最新文献

英文中文

Coronary bypass without cardiopulmonary bypass 无体外循环的冠状动脉旁路手术

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90026-X

B.P. Bidstrup

引用次数: 4

The society of thoracic surgeons database: A progress report 胸外科学会数据库:进展报告

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90017-9

J.A. Smith, M. Rabinov, A. Pick, B.B. Davis, R.F. Salamonsen, D.S. Esmore

引用次数: 0

Minimally invasive off-pump coronary “octopus” device for local stabilisation of anastomotic construction 微创非体外循环冠状动脉“章鱼”装置用于吻合口结构局部稳定

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90029-5

J. Tatoulis

引用次数: 0

Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary artery bypass grafting 超低剂量抑蛋白蛋白降低了输血需求，在冠状动脉旁路移植术中具有成本效益

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90013-1

R. Dignan, D. Law, P. Seah, C. Manganas, M. Chesti, H. Wolfenden

引用次数: 0

Minimally invasive cardiac surgery via hemisternotomy 经半胸切开术的微创心脏手术

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90010-6

R. Tam, A. Almeida

引用次数: 0

Is it safe to salvage blood from the pericardium during cardiac surgery? 在心脏手术中从心包中抢救血液安全吗?

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90014-3

Mark Newman, Matt Sheminant

引用次数: 0

Effects of the omega-3 fatty acids on vascular tone in hypercholesterolaemia and balloon arterial injury omega-3脂肪酸对高胆固醇血症和球囊动脉损伤患者血管张力的影响

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90006-4

Mary B. Engler Phd , Marguerite M. Engler Phd , Margaret Mayes Ms , Philip C. Ursell Md

Dietary polyunsaturated fatty acids (ω-3 PUFAs) are associated with reduced coronary heart disease (CHD) risk. To define mechanisms, we investigated the vasoactive properties of these fatty acids in a rat model of hypercholesterolaemia (HC) and balloon arterial injury. Mature Wistar Kyoto (WKY) rats were fed a control (C), HC-inducing diet or a HC diet after aortic balloon injury (HC+EI) for 3 weeks. Serum cholesterol (mg/dL) was increased in HC (793±31) and HC+EI (857±36) as compared to C (85±3, p≤0.001). Cumulative concentration-response curves to norepinephrine (NE, 10⁻⁹ to 10⁻⁵ mol/L) followed by docosahexaenoic (DHA) or eicosapentaenoic (EPA) (1 to 100 μmol/L) were generated in isolated aortic rings (intact and de-endothelialised, E-). Overall, contractions to NE (10⁻⁹ to 10⁻⁵ mol/L) in intact rings were diminished in HC and HC+EI groups than were apparent in the C group (p≤0.001). De-endothelialised rings exhibited much greater NE contractile responses as compared to intact rings from each of the 3 groups. Endothelium-dependent relaxations to acetylcholine (10⁻⁷ to 10⁻⁴ mol/L) were significantly decreased in the HC+EI group. Relaxant responses to the ω-3 PUFAs, DHA and EPA (1–100 μmol/L) were similar in intact rings, but enhanced in E- rings among the 3 groups. De-endothelialised ring responses were −8.6 to −35.5% (C), −8.4 to −30.5% (HC), −7.8 to −25.6% (HC+EI) to DHA (1–100 μmol/L) and −6.8 to −339% (C), −4.8 to =t-40.8% (HC), −8.9 to −34.6% (HC+EI) to EPA (1–100 μmol/L). In areas of aortic intimal hyperplasia, lipid deposition quantified spectrophotometrically using oil red O (ORO) was greater in HC+EI (0.539 μmol ORO/mm² aortic tissue, p<0.001) as compared to C (0.292) and HC (0.315) groups. We conclude that (1) aortic contractile properties to NE are altered in rats with HC and HC+EI, (2) dietary HC after aortic injury leads to intimal hyperplasia/lipid deposition and impaired endothelium-dependent relaxations in WKY rats, and (3) ω-3 PUFAs have vasorelaxant properties in HC and HC+EI rat aorta. These properties may be beneficial in CHD.

膳食多不饱和脂肪酸(ω-3 PUFAs)与降低冠心病(CHD)风险相关。为了明确机制，我们在高胆固醇血症(HC)和球囊动脉损伤的大鼠模型中研究了这些脂肪酸的血管活性特性。成年Wistar Kyoto (WKY)大鼠在主动脉球囊损伤(HC+EI)后分别饲喂对照(C)、HC诱导饮食或HC饮食3周。HC组(793±31)和HC+EI组(857±36)血清胆固醇(mg/dL)高于C组(85±3,p≤0.001)。去甲肾上腺素(NE, 10−9 ~ 10−5 mol/L)、二十二碳六烯烯(DHA)或二十碳五烯烯(EPA) (1 ~ 100 μmol/L)对离体主动脉环(完整和去内皮化，E-)的累积浓度-响应曲线。总的来说，HC组和HC+EI组完整环内NE(10−9 ~ 10−5 mol/L)的收缩比C组明显减少(p≤0.001)。与三组完整的环相比，去内皮化环表现出更大的NE收缩反应。HC+EI组对乙酰胆碱的内皮依赖性松弛(10−7 ~ 10−4 mol/L)显著降低。ω-3 PUFAs、DHA和EPA (1-100 μmol/L)的松弛反应在完整环中相似，但在E-环中增强。去内皮环对DHA (1-100 μmol/L)的反应为−8.6 ~−35.5% (C)，−8.4 ~−30.5% (HC)，−7.8 ~−25.6% (HC+EI)，对EPA (1-100 μmol/L)的反应为−6.8 ~−339% (C)，−4.8 ~ =t-40.8% (HC)，−8.9 ~−34.6% (HC+EI)。在主动脉内膜增生区域，与C组(0.292)和HC组(0.315)相比，HC+EI组的脂质沉积(0.539 μmol ORO/mm2, p<0.001)比HC组(0.292)更大。我们得出结论:(1)HC和HC+EI大鼠主动脉对NE的收缩特性发生改变;(2)WKY大鼠主动脉损伤后饮食HC导致内膜增生/脂质沉积和内皮依赖性松弛功能受损;(3)ω-3 PUFAs在HC和HC+EI大鼠主动脉中具有血管松弛特性。这些特性可能对冠心病有益。

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引用次数: 8

Lambl's excrescences inside the left ventricle due to rheumatic mitral stenosis 风湿性二尖瓣狭窄引起的左心室兰博氏赘生物

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90008-8

Solomon Victor FRCP, Vijaya M. Nayak MS, Neelamani Murthy MD, Elangovan DM

A patient with chronic rheumatic mitral stenosis had Lambl's excrescences at the site where the jet of blood through the stenotic mitral orifice impinged on the interventricular septum. There is dispute whether Lambl's excrescences are neoplastic or related to chronic trauma. The present case adds credence to the latter view.

慢性风湿性二尖瓣狭窄患者在狭窄的二尖瓣口血流撞击室间隔处出现兰博氏赘生物。兰博氏赘生物是肿瘤还是与慢性创伤有关尚无定论。目前的案例进一步证实了后一种观点。

引用次数: 0

Low-dose postoperative aprotinin reduces blood transfusion requirements in primary CABG patients on aspirin 术后低剂量抑酶蛋白降低原发性冠脉搭桥患者服用阿司匹林的输血需求

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90025-8

J.M. Alvarez, L.R. Jackson, J. Smolich, C. Chatwin

引用次数: 0

Occlusive wrap dressing reduces infection rate in long saphenous vein harvest sites 封闭敷料可降低长隐静脉采收部位的感染率

The Asia Pacific Heart Journal

Pub Date : 1999-05-01 DOI: 10.1016/S1328-0163(99)90023-4

J. Negri, F.L. Rosenfeldt, D. Holdaway, M. Grigg, B.B. Davis, D.S. Esmore

引用次数: 0

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