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Quality and risk assessment of lead and cadmium in drinking water for child development centres use in Phatthalung province, Thailand 泰国法塔隆省儿童发展中心使用的饮用水中铅和镉的质量和风险评估
Pub Date : 2023-10-12 DOI: 10.5620/eaht.2023020
Somsiri Decharat, Piriyalux Phethuayluk
The purpose of this cross-sectional study and research was to evaluate the health risks to children in relation to the concentration of lead and cadmium in drinking water. Samples were collected between 1 May 2020 and 15 October 2020. Thirty-three child development centres, Phatthalung province, Thailand. Two hundred and ten drinking water samples were taken, consisting of 66 bottled water samples, 66 tap water samples, 66 filtered tap water samples and 12 raw water samples for using in the child development centres. Concentrations of lead and cadmium were identified by graphite furnace atomic absorption spectrometry. The concentration of cadmium in bottled water samples, tap water samples, filtered tap water samples, and raw water samples ranged from nd - 0.0020mg/L, nd - 0.0049 mg/L, nd - 0.0018 mg/L and nd - 0.0049 mg/L. The summation of the total hazard index of bottled water samples, tap water samples, filtered tap water, and raw water samples was less than 1, was considered health-protective. The results will provide the direct evidence needed by child development centres managers to warn learners about the health risk of drinking water among children.
这项横断面研究的目的是评估饮用水中铅和镉的浓度对儿童的健康风险。样本于2020年5月1日至2020年10月15日期间收集。泰国法塔隆省33个儿童发展中心。抽取了210个饮用水样本,包括66个瓶装水样本、66个自来水样本、66个过滤自来水样本和12个供儿童发展中心使用的原水样本。采用石墨炉原子吸收光谱法测定了铅和镉的浓度。瓶装水样品、自来水样品、过滤自来水样品和原水样品中的镉浓度范围为nd - 0.0020mg/L、nd - 0.0049 mg/L、nd - 0.0018 mg/L和nd - 0.0049 mg/L。瓶装水样品、自来水样品、过滤自来水样品和原水样品的总危害指数之和小于1,认为对健康有益。研究结果将为儿童发展中心的管理者提供所需的直接证据,以警告学习者儿童饮用水的健康风险。
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引用次数: 0
Generation, types and impacts of biomedical waste during COVID-19: Indian context 2019冠状病毒病期间生物医学废物的产生、类型和影响:印度背景
Pub Date : 2023-10-10 DOI: 10.5620/eaht.2023019
None Shefali
India's already-stressed waste disposal system has been strained by the COVID-19 outbreak. The challenge of managing biomedical Waste (BMW) in India has become more complicated in recent years, mainly due to the sudden emergence of COVID-19. As a methodology, a literature review was carried out with the help of Google Scholar, Research Gate, PubMed, and academic journal databases. Additionally, publications from numerous non-academic sources (such as news websites etc.) and current guidelines, such as those from the Ministry of Health and Family Welfare, Government of India, were also accessed. The review study identifies that PPE (Personal Protective Equipment) made up the majority of biomedical waste, followed by vaccine waste, during the peak of the COVID-19 vaccination campaign. The increase in PPEs such as face masks, aprons, face shields, gloves, goggles, and sanitizers, as well as other medical waste like bandages, plastic containers, syringes, testing kits, and tissues, has significantly changed the makeup of the BMW. This pandemic has hampered the proper management of solid waste, which has now surfaced as a major threat to developing countries. In this paper, biomedical waste management strategies followed in India and its disposal methods, cost-effective and environment-friendly methods to treat medical waste are also discussed.
印度本已压力重重的废物处理系统因COVID-19疫情而变得更加紧张。近年来,印度管理生物医学废物的挑战变得更加复杂,这主要是由于COVID-19的突然出现。作为一种方法,在Google Scholar、Research Gate、PubMed和学术期刊数据库的帮助下进行了文献综述。此外,还查阅了许多非学术来源(如新闻网站等)的出版物和现行准则,如印度政府卫生和家庭福利部的准则。审查研究确定,在COVID-19疫苗接种运动的高峰期,个人防护装备(PPE)占生物医学废物的大部分,其次是疫苗废物。口罩、围裙、面罩、手套、护目镜、洗手液等个人防护用品,以及绷带、塑料容器、注射器、检测包、纸巾等医疗垃圾的增加,极大地改变了宝马的构成。这种流行病阻碍了对固体废物的适当管理,固体废物现已成为发展中国家面临的主要威胁。本文还讨论了印度遵循的生物医学废物管理战略及其处置方法,成本效益和环境友好型处理医疗废物的方法。
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引用次数: 0
Bioaccumulation of pesticides in fish resulting toxicities in humans through food chain and forensic aspects. 农药在鱼类中的生物累积通过食物链和法医学方面对人类产生毒性。
Pub Date : 2023-09-01 Epub Date: 2023-08-28 DOI: 10.5620/eaht.2023017
Suryapratap Ray, Sanjana Thanjan Shaju

A crucial component for agricultural productivity is pesticide application. Increased usage of pesticides has significantly increased agricultural output, reduced grain losses in storage, and overall enhanced human wellbeing. Globally, every year approximately 3 billion kg of pesticides are used which budgets around 40 billion USD. Pesticide use can leave behind unwanted residues that can contaminate food, the environment, and living tissues. They are known to spread from agricultural regions that have been treated into the wider environment, where they affect non-target creatures. All tiers of biological organisms, directly impacted by this exposure. Pesticides at sub-lethal levels alter every aspect of a fish's physiology, including histology, haematology, defence mechanisms, and behaviour. The same topic of pesticide toxicology is the emphasis of this article, which also addresses some important induced chronic toxicological effects of pesticides in fish and the extent of their bioaccumulation in fish tissues. The data represents the largest bodies of water, such as rivers and lakes, that have been contaminated by pesticides, notably due to pesticide drift. It has been discussed how readily pesticides are absorbed into fish bodies and how this enters the food chain inducing harmful impacts on human health when consumed.

农业生产力的一个重要组成部分是施用农药。农药使用量的增加显著提高了农业产量,减少了粮食储存损失,总体上改善了人类福祉。在全球范围内,每年大约使用30亿公斤农药,预算约为400亿美元。使用农药会留下不需要的残留物,从而污染食物、环境和活体组织。众所周知,它们会从经过处理的农业地区传播到更广阔的环境中,在那里影响非目标生物。所有层次的生物有机体,直接受到这种暴露的影响。亚致死水平的杀虫剂改变了鱼类生理学的方方面面,包括组织学、血液学、防御机制和行为。农药毒理学是本文的重点,它还涉及农药在鱼类中的一些重要的诱导慢性毒理学效应及其在鱼类组织中的生物累积程度。这些数据代表了被农药污染的最大水体,如河流和湖泊,特别是由于农药漂移。人们已经讨论了农药被鱼体内吸收的可能性,以及农药如何进入食物链,在食用时对人类健康产生有害影响。
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引用次数: 0
Seasonal and diurnal measurement of ambient benzene at a high traffic inflation site in Delhi: Health risk assessment and its possible role in ozone formation pathways. 德里交通拥堵高发区环境苯的季节性和昼夜测量:健康风险评估及其在臭氧形成途径中的可能作用。
Pub Date : 2023-09-01 Epub Date: 2023-08-23 DOI: 10.5620/eaht.2023016
Poonam Kumari, Daya Soni, Shankar G Aggarwal, Khem Singh

Benzene is the most toxic and hazardous pollutant among volatile organic compounds (VOCs), as it comes under group 1 carcinogens recognized by the International Agency for Research on Cancer (IARC). It also plays a significant role in forming secondary pollutants like ozone. The benzene concentration was measured using a charcoal sorbent tube by active sampling at a traffic junction and analysis was done using GC-FID. The maximum average concentration of benzene in ambient air was found to be 33 μg/m3. A diurnal study of benzene measurement shows higher benzene concentrations in the evening compared to the morning. Seasonal variation of benzene is found to be winter > spring > summer > autumn > monsoon and OFP was found to be 21, 19, 14, 13, and 10 respectively. Cancer (ILCR) and non-cancer (HQ) health risk assessment was done to determine the impact of ambient benzene on the residents of urban areas. The yearly average value of ILCR was found to be 2×10-6 ± 1×10-6 which ranges from acceptable value to three times the WHO acceptable value i.e 1×10-6. The correlation of ozone and its precursor, benzene with meteorological parameters is also evaluated. The correlation of benzene and ozone with solar radiation shows the influence of photochemical reactions on the levels of benzene and ozone at the study site, although it is low.

苯是挥发性有机化合物(VOCs)中毒性和危害最大的污染物,因为它属于国际癌症研究机构(IARC)认可的第1类致癌物。它在形成臭氧等二次污染物方面也发挥着重要作用。通过在交通路口进行主动采样,使用木炭吸附管测量苯浓度,并使用GC-FID进行分析。环境空气中苯的最大平均浓度为33微克/立方米。苯测量的昼夜研究表明,与早上相比,晚上的苯浓度更高。苯的季节变化为冬季>春季>夏季>秋季>季风,OFP分别为21、19、14、13和10。通过癌症(ILCR)和非癌症(HQ)健康风险评估来确定环境苯对城市居民的影响。ILCR的年平均值为2×10-6±1×10-6,范围从可接受值到世界卫生组织可接受值的三倍,即1×10-6。还评价了臭氧及其前体苯与气象参数的相关性。苯和臭氧与太阳辐射的相关性表明,光化学反应对研究地点苯和臭氧水平的影响虽然很低。
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引用次数: 0
Comparison of acetylcholinesterase among employees based on job positions and personal protective equipment in fuel station. 基于加油站工作岗位和个人防护装备的员工乙酰胆碱酯酶比较。
Pub Date : 2023-09-01 Epub Date: 2023-09-27 DOI: 10.5620/eaht.2023018
Chan Pattama Polyong, Anamai Thetkathuek

The purpose of this study was to compare the levels of acetylcholinesterase (AChE) among employees based on job positions and the wearing of personal protective equipment (PPE) in fuel station areas. The sample group consisted of 200 people sorted into various groups, including (i) Inside fuel dispenser area (I-FDA) group consisting of 100 employees for refueling, cashier, and loading fuel into storage tanks, and (ii) Outside fuel dispenser area (O-FDA) group, consisting of 100 employees working in convenience stores, food stores, coffee shops, and offices, as well as general staff and car washers. Data were collected using interview questionnaires and blood samples were analyzed for AChE activity. The results showed that the I-FDA group had a significantly lower mean of serum AChE (7.38±1.73 U/ml) than the O-FDA group (7.85±1.49 U/ml) (p<0.05). The I-FDA group had a 2.43 times higher risk of abnormal serum AChE than the O-FDA group (OR=2.43, 95%CI=1.05-5.60). When considering the risk factors for job positions, it was found that refueling and cashier positions had lower AChE activity levels than those who did not (p<0.05). In the part, employees for food sales in a closed building and those wearing PPE masks had significantly higher AChE activity levels than those who did not or who wore them (p<0.05). Based on the aforementioned, employers at fuel stations should strictly determine the appropriate measures for wearing a PPE mask. Further, employees should be provided accommodation away from oil supply or enclosed buildings during breaks to reduce the effects on the neurotransmitter.

本研究的目的是根据加油站区域的工作岗位和个人防护装备的穿戴情况,比较员工的乙酰胆碱酯酶(AChE)水平。样本组由200人组成,分为不同的组,包括(i)内部加油区(i-FDA)组,由100名员工组成,负责加油、收银和将燃料装入储罐;(ii)外部加油区(O-FDA)组由100名在便利店、食品店、咖啡店和办公室工作的员工组成,以及一般工作人员和洗车工。使用访谈问卷收集数据,并分析血液样本中乙酰胆碱酯酶活性。结果表明,I-FDA组血清AChE平均值(7.38±1.73U/ml)明显低于O-FDA组(7.85±1.49U/ml)(p
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引用次数: 0
Organ wide toxicological assessment of common edible herbs and their mixtures as used in home remedies 在家庭疗法中使用的普通食用草药及其混合物的全器官毒理学评估
Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023012
Chigeru Wodi, Ebere Ezaka, B. Ukwah, U. Eze
The use of home remedies for medicinal purposes, most of which are edible plants has continued to be a practice in many homes. However, there has been an increasing report of chronic use with lethal effect. Among the commonly used herbal/ medicinal plants were ginger, garlic and lemon. These were seen to be prevalent across continents with brewing and crude extraction being the most means of consumption. This study investigated the organ wide toxicity of this extract following chronic consumption of crude extract. Twenty-five albino Wister rats, five in each group were used for this experiment. Each animal received 0.5ml/kg body weight of either ginger extract, garlic extract, lemon juice, or a mixture of equal volumes of all three extract (v/v) respectively twice daily for seven (7) days. Statistics were represented as ±SE; P≤0.05 was considered significant. Previous studies have shown that moderate consumption of these medicinal plants were beneficial and have shown no deleterious effect. This study observed no change in the weight of the experimental animals. The weight of the animals continued to increase except for the group that received lemon and the mixture, but these were not significant. It was observed that chronic consumption induced organ wide toxicity to include the liver, kidney, intestinal epithelium, stomach, and pancreas. These were shown to alter tissue architecture and the cell morphology. Packed cell volume was reduced in the lemon and the group that received a combination of all extracts (p=o.03). Blood differentials showed changes in levels. An elevated basophil level was observed in ginger and garlic (p<0.0001; p=0.0006). Monocyte levels increased progressively across each group when compared to the control with the most elevated level seen in the group that received the mixture (p<0.0001). Lymphocyte count was reduced across all the groups that received the extract except for animals that received ginger. This study suggests the application of caution among users of these medicinal plants and continues to draw attention to the need for harmonization and standardization of safe use doses.
在许多家庭中,使用家庭疗法用于医疗目的,其中大部分是可食用的植物,这一直是一种做法。然而,有越来越多的报告称,长期使用会产生致命影响。常用的草药/药用植物有姜、大蒜和柠檬。这些在各大洲都很普遍,酿造和原油提取是最主要的消费方式。本研究考察了长期食用粗提取物后的全器官毒性。实验选用白化Wister大鼠25只,每组5只。每只动物接受每公斤体重0.5ml的生姜提取物、大蒜提取物、柠檬汁,或三种提取物的等量混合物(v/v),每天两次,连续7天。统计量用±SE表示;P≤0.05被认为是显著的。以前的研究表明,适度食用这些药用植物是有益的,并没有显示出有害的影响。本研究未观察到实验动物体重的变化。除了吃柠檬和混合物的那一组外,其他动物的体重继续增加,但这并不显著。观察到,长期食用可引起包括肝、肾、肠上皮、胃和胰腺在内的全器官毒性。这些物质被证明可以改变组织结构和细胞形态。柠檬和接受所有提取物组合的组的填充细胞体积减少(p= 0.03)。血液差异显示出水平的变化。生姜和大蒜的嗜碱性粒细胞水平升高(p<0.0001;p = 0.0006)。与对照组相比,各组单核细胞水平逐渐升高,接受混合物的组中单核细胞水平最高(p<0.0001)。除了接受生姜提取物的动物外,所有接受提取物的动物的淋巴细胞计数都减少了。这项研究表明,这些药用植物的使用者应谨慎使用,并继续提请注意安全使用剂量的统一和标准化的必要性。
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引用次数: 0
Carcinogenic and non-carcinogenic risk assessment of consuming metal-laden wild mushrooms in Nigeria: Analyses from field based and systematic review studies. 尼日利亚食用含金属野生蘑菇的致癌性和非致癌性风险评估:基于实地和系统审查研究的分析。
Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023013
K. S. Chukwuka, S. O. Adesida, C. Alimba
This study investigated the potential health risk associated with the consumption of metal-laden mushrooms in Nigeria. Concentrations of Pb, Cd, Cr, Cu, Ni, Zn and Al in wild mushrooms collected from the Nigerian environment were measured using atomic absorption spectrometer. Also, systematic analysis of articles on metal accumulation in mushrooms from Nigeria were obtained from scientific databases. Using hazard model indices, the metal concentration in mushrooms were evaluated for their potential carcinogenic and non-carcinogenic health risk when consumed by adults and children. Zn and Cd, respectively, had the highest and lowest mean concentrations (mg kg-1) in the analysed mushrooms from the field study, while Fe and Co, respectively, had the highest and lowest mean concentrations (mg kg-1) in the systematically reviewed articles. In the field study, the percentage distribution of THQ of the heavy metals greater than 1 was 0% and 42.85% for adults and children respectively. While for the systematic study, 30% and 50% of the heavy metals for adults and children respectively exceeded the limit of 1. The hazard indices obtained from both the systematic and field studies for both age groups were all >1, indicating significant health risk. The findings from both the systematic and field studies revealed that consuming metal-laden mushrooms by adults and children increases the carcinogenic risk to Cd, Cr, and Ni since they exceeded the acceptable limit of 1E-04 stated by USEPA guideline. Based on the findings from the systematic and field studies, it suggests that consuming mushrooms collected from metal polluted substrates increases carcinogenic and non-carcinogenic health risk among Nigerians.
本研究调查了尼日利亚与食用含金属蘑菇有关的潜在健康风险。采用原子吸收光谱仪测定了尼日利亚野生蘑菇中Pb、Cd、Cr、Cu、Ni、Zn和Al的含量。并对尼日利亚产蘑菇中金属积累的相关文献进行了系统分析。利用危害模型指数,评价了成人和儿童食用蘑菇时,蘑菇中金属浓度的潜在致癌和非致癌健康风险。在系统综述的文章中,野外分析的蘑菇中锌和镉的平均浓度分别最高和最低(mg kg-1),铁和钴的平均浓度分别最高和最低(mg kg-1)。在野外研究中,成人和儿童中大于1的重金属THQ的百分比分布分别为0%和42.85%。而在系统研究中,30%的成人和50%的儿童重金属超标。两个年龄组的系统调查和实地调查得出的危害指数均为bbb1,表明存在显著的健康风险。系统研究和实地研究的结果表明,成人和儿童食用含金属蘑菇会增加镉、铬和镍的致癌风险,因为它们超过了美国环保署指导方针规定的可接受限度1E-04。根据系统和实地研究的结果,它表明,食用从金属污染的基质中采集的蘑菇会增加尼日利亚人的致癌和非致癌健康风险。
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引用次数: 0
Biochemical and histopathological changes in livers of rats poisoned with aluminum phosphide and treated with carrot extract 磷化铝中毒和胡萝卜提取物处理大鼠肝脏的生化和组织病理学变化
Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023014
A. H. Al-Safar, Rafat A. Mohammed Jawad, H. Khayoon, M. A. Alsaadawi, K. H. Zenad, Z. Saeed, M. Alkhaled
The experimental studies of Aluminum Phosphide (AP) poisoning in rats revealed several clinical and pathological signs such as hemorrhage, sinusoidal dilatation, bile stasis, centrilobular necrosis, Kupffer cell hyperplasia, infiltration by mononuclear cells, and fatty infiltration in the liver tissues. This paper aimed to show the impact of carrots on the toxic effect of AP on the livers of adult rats (female). To investigate some biochemical and histopathological changes effects of AP in rats, sixty white female rats were equally divided into four groups, the first group (G1) was administered orally with 3mg/kg/ body weight of AP, the second group (G2) was orally treated with AP and 10% carrot extract at the same time. The third group (G3) administrated 10% carrot extract only. The fourth (G4) group was the negative control and was treated with distilled water only. The experiments continued for a month at the animal house of the Veterinary Medicine College of Baghdad University. The results revealed that high levels of liver enzymes and bilirubin were induced in G1 with decreasing total protein levels. The pathological examination revealed the presence of marked proliferation of Kupffer cells in G1 livers. However, the G2 group showed slight infiltration of lymphocytes in sinusoids. The pathological changes in the livers of G3 group showed slight cloudy swelling in hepatocytes compared with the normal texture of hepatocytes in G4. The data of this experiment showed that treatment with carrot extract significantly decreases the elevation in the level of liver function enzymes in animal poisoned with AP. In addition, treatment with carrot extract reduces the severe damage in the hepatic tissue that occurred in rats treated with AP only. In general, it could be concluded that treatment with carrot extract provides a remedial effect against the hepatotoxicity that is resulted from exposure to AP.
磷化铝(AP)中毒大鼠的实验研究显示出出血、窦窦扩张、胆汁淤积、小叶中心坏死、库普弗细胞增生、单核细胞浸润、肝组织脂肪浸润等临床病理表现。本文旨在研究胡萝卜对成年大鼠(雌性)肝脏中AP毒性作用的影响。为了研究AP对大鼠的一些生化和组织病理学改变的影响,将60只雌性白色大鼠分为4组,第一组(G1)口服AP 3mg/kg/体重,第二组(G2)同时口服AP和10%胡萝卜提取物。第三组(G3)仅给予10%胡萝卜提取物。第四组(G4)为阴性对照,仅用蒸馏水处理。实验在巴格达大学兽医学院的动物室进行了一个月。结果显示,G1期肝酶和胆红素水平升高,总蛋白水平降低。病理检查显示G1肝中存在明显的Kupffer细胞增殖。G2组鼻窦区淋巴细胞有轻微浸润。与G4肝细胞质地正常相比,G3组肝脏病理变化表现为肝细胞轻度浑浊肿胀。本实验数据表明,胡萝卜提取物处理显著降低了AP中毒动物肝功能酶水平升高,并且胡萝卜提取物处理减轻了AP单独处理大鼠肝组织的严重损伤。总的来说,可以得出结论,胡萝卜提取物对暴露于AP引起的肝毒性具有补救作用。
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引用次数: 0
Association of triclosan and human infertility: A systematic review. 三氯生与人类不孕症的关系:一项系统综述。
Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023015
Belén Daza-Rodríguez, Dilia Aparicio-Marenco, Johana Márquez-Lázaro
Triclosan (TCS) is a chemical compound, which has antibacterial, antiviral, and antifungal properties. TCS is considered an endocrine-disrupting chemical, which has been shown to interfere with developmental, behavioral, and reproductive outcomes in biological models and cell cultures. However, implications about exposure to TCS and human infertility are rare. Thus, the main of this review is summarize the available evidence of the association between triclosan exposure on human infertility. For this, systematic review was conducted following the recommendations established in Report of Systematic Reviews and Meta-Analyses guide (PRISMA). Initially, an electronic search in MEDLINE (via PubMed) and Science direct was performed. The methodological quality of the included studies was verified through the Joanna Briggs Institute (JBI) checklists. All selection and data extraction processes were carried out independently by two reviewers. The evidence was organized and presented using tables and narrative synthesis. There is lacking evidence about the association between triclosan and human infertility. Overall, no association between triclosan and infertility was found. However, semen quality and ovarian reserve are susceptible to triclosan exposure. Thus, future studies are still needed to better elucidate the associations between triclosan and infertility outcomes.
三氯生(TCS)是一种具有抗菌、抗病毒和抗真菌特性的化合物。TCS被认为是一种干扰内分泌的化学物质,在生物模型和细胞培养中已被证明会干扰发育、行为和生殖结果。然而,暴露于TCS和人类不育的影响是罕见的。因此,本综述的主要内容是总结三氯生暴露与人类不孕症之间关系的现有证据。为此,按照《系统评价和荟萃分析报告指南》(PRISMA)中的建议进行了系统评价。最初,在MEDLINE(通过PubMed)和Science direct中进行了电子搜索。纳入研究的方法学质量通过乔安娜布里格斯研究所(JBI)检查清单进行验证。所有选择和数据提取过程均由两名审稿人独立进行。证据是用表格和叙事综合来组织和呈现的。缺乏证据表明三氯生与人类不孕症之间存在关联。总体而言,没有发现三氯生与不孕症之间的关联。然而,精液质量和卵巢储备易受三氯生暴露的影响。因此,未来的研究仍需要更好地阐明三氯生与不孕症结局之间的关系。
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引用次数: 0
Potential Toxic elements in shellfish from three rivers in Niger Delta, Nigeria: bioaccumulation, dietary intake, and human health risk assessment 尼日利亚尼日尔三角洲三条河流贝类中潜在有毒元素:生物积累、膳食摄入和人类健康风险评估
Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023011
B. Onyegeme-okerenta, Levi Okeinaye West
Human health risks associated with the consumption of three shellfish (Penaeus monodon, Crassostrea rhizophorae, and Tympanostomus fuscatus) harvested from the Buguma, Krakrama, and Bonny Rivers in the Niger Delta region were evaluated in this study. The bioaccumulation of potential toxic elements (PTEs) [Arsenic (As), Cadmium (Cd), Chromium (Cr), Lead (Pb), and Nickel (Ni)] was analyzed using atomic absorption spectrophotometry (AAS). The pollution index (PPI), estimated daily intake (EDI), target hazard quotient (THQ), total hazard index (HI), target cancer risk (CR), and total cancer risk (TCR) were evaluated for potential human health risks. The bioaccumulation levels of PTEs in shellfish samples followed the order: Ni > Cr > Pb > Cd > As and were above standard recommended limits except for inorganic As levels observed in T. fuscatus and P. monodon samples from Krakrama and Bonny and C. rhizophorae from Bonny river. The EDI values for iAs, Cr, and Ni were lower than the tolerable daily intake (TDI), however, the EDI of Cd for children in P. monodon (4.6E-03 mg kg-1day-1), T. fuscatus (1.7E-03 mg kg-1day-1) and C. rhizophorae (1.4E-03 mg kg-1day-1) from Buguma were higher than the TDI value (8.00E-04 mg kg-1day-1). The HI values were above 1. The total cancer risk (TCR) values of all analyzed PTEs for all the shellfish species from the rivers for children and adults ranged from 8.69E-04 to 2.47E-03 and 1.86E-03 to 5.30E-03 respectively and these were higher than the priority risk level (1E-04), hence, the need to monitor shellfish consumption in the study area.
本研究评估了从尼日尔三角洲地区的布古马河、喀拉拉马河和邦尼河收获的三种贝类(单齿对虾、根瘤贝和褐鼓囊虫)的食用相关的人类健康风险。采用原子吸收分光光度法(AAS)分析了潜在有毒元素(pte)[砷(As)、镉(Cd)、铬(Cr)、铅(Pb)和镍(Ni)]的生物积累。评价污染指数(PPI)、估计日摄入量(EDI)、目标危害商(THQ)、总危害指数(HI)、目标致癌风险(CR)和总致癌风险(TCR)对人体健康的潜在危害。贝类样品中pte的生物积累水平依次为Ni > Cr > Pb > Cd > As,除来自喀拉玛和邦尼河的fuscatus和P. monodon以及来自邦尼河的C. rhizophorae样品中无机As外,其余样品均高于标准推荐限量。砷、铬和镍的EDI值均低于可耐受日摄取量(TDI),而布古马单斑孢霉(4.6E-03 mg kg-1day-1)、褐皮孢霉(1.7E-03 mg kg-1day-1)和根茎孢霉(1.4E-03 mg kg-1day-1)对Cd的EDI值均高于可耐受日摄取量(8.00E-04 mg kg-1day-1)。HI值大于1。儿童和成人的总致癌风险(TCR)分别为8.69E-04 ~ 2.47E-03和1.86E-03 ~ 5.30E-03,高于优先风险水平(1E-04),有必要对研究区贝类消费进行监测。
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Environmental analysis, health and toxicology
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