A crucial component for agricultural productivity is pesticide application. Increased usage of pesticides has significantly increased agricultural output, reduced grain losses in storage, and overall enhanced human wellbeing. Globally, every year approximately 3 billion kg of pesticides are used which budgets around 40 billion USD. Pesticide use can leave behind unwanted residues that can contaminate food, the environment, and living tissues. They are known to spread from agricultural regions that have been treated into the wider environment, where they affect non-target creatures. All tiers of biological organisms, directly impacted by this exposure. Pesticides at sub-lethal levels alter every aspect of a fish's physiology, including histology, haematology, defence mechanisms, and behaviour. The same topic of pesticide toxicology is the emphasis of this article, which also addresses some important induced chronic toxicological effects of pesticides in fish and the extent of their bioaccumulation in fish tissues. The data represents the largest bodies of water, such as rivers and lakes, that have been contaminated by pesticides, notably due to pesticide drift. It has been discussed how readily pesticides are absorbed into fish bodies and how this enters the food chain inducing harmful impacts on human health when consumed.
Benzene is the most toxic and hazardous pollutant among volatile organic compounds (VOCs), as it comes under group 1 carcinogens recognized by the International Agency for Research on Cancer (IARC). It also plays a significant role in forming secondary pollutants like ozone. The benzene concentration was measured using a charcoal sorbent tube by active sampling at a traffic junction and analysis was done using GC-FID. The maximum average concentration of benzene in ambient air was found to be 33 μg/m3. A diurnal study of benzene measurement shows higher benzene concentrations in the evening compared to the morning. Seasonal variation of benzene is found to be winter > spring > summer > autumn > monsoon and OFP was found to be 21, 19, 14, 13, and 10 respectively. Cancer (ILCR) and non-cancer (HQ) health risk assessment was done to determine the impact of ambient benzene on the residents of urban areas. The yearly average value of ILCR was found to be 2×10-6 ± 1×10-6 which ranges from acceptable value to three times the WHO acceptable value i.e 1×10-6. The correlation of ozone and its precursor, benzene with meteorological parameters is also evaluated. The correlation of benzene and ozone with solar radiation shows the influence of photochemical reactions on the levels of benzene and ozone at the study site, although it is low.
The purpose of this study was to compare the levels of acetylcholinesterase (AChE) among employees based on job positions and the wearing of personal protective equipment (PPE) in fuel station areas. The sample group consisted of 200 people sorted into various groups, including (i) Inside fuel dispenser area (I-FDA) group consisting of 100 employees for refueling, cashier, and loading fuel into storage tanks, and (ii) Outside fuel dispenser area (O-FDA) group, consisting of 100 employees working in convenience stores, food stores, coffee shops, and offices, as well as general staff and car washers. Data were collected using interview questionnaires and blood samples were analyzed for AChE activity. The results showed that the I-FDA group had a significantly lower mean of serum AChE (7.38±1.73 U/ml) than the O-FDA group (7.85±1.49 U/ml) (p<0.05). The I-FDA group had a 2.43 times higher risk of abnormal serum AChE than the O-FDA group (OR=2.43, 95%CI=1.05-5.60). When considering the risk factors for job positions, it was found that refueling and cashier positions had lower AChE activity levels than those who did not (p<0.05). In the part, employees for food sales in a closed building and those wearing PPE masks had significantly higher AChE activity levels than those who did not or who wore them (p<0.05). Based on the aforementioned, employers at fuel stations should strictly determine the appropriate measures for wearing a PPE mask. Further, employees should be provided accommodation away from oil supply or enclosed buildings during breaks to reduce the effects on the neurotransmitter.