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Designing movement space for elderly and disabled people in the construction law in selected countries. 在选定国家的建筑法中为老年人和残疾人设计活动空间。
Pub Date : 2024-07-25 Epub Date: 2024-06-14 DOI: 10.13075/mp.5893.01512
Przemysław Nowakowski, Barbara Gronostajska

Background: Building law regulations determine designing the built environment recognising the needs of users of different ages and psychophysical abilities. Seniors and their spatial needs are covered there to a limited extent. The benchmark for design are wheelchair users. Their spatial requirements are greater in relation to independent walkers, including most older people. This makes it difficult to adapt the whole built environment to the needs of people with less mobility dysfunction. This can be considered in terms of spatial design and investment costs.

Material and methods: The paper analyses the building regulations of 3 countries in terms of legal conditions to shape the architectural movement space of older people and disabled people. Analytical and comparative methods are used. Such research is becoming relevant and necessary. The analyses are conducted in the context of ageing populations. They are justified by statistical data on the age groups of Polish society. This is followed by design analyses of the legal requirements in the wheelchair movement space and proposals for alternatives, e.g., people walking with canes (case study). Their aim is to indicate methods to limit excessive communication spaces in buildings while maintaining functional values for all users.

Results: Research may show the possibility of greater diversification of regulations and alternatives to current laws. They are dedicated to participants in investment processes to shape accessible buildings. They can also be used in legislative work on amendments to the construction law.

Conclusions: Changes in building regulations and a detailed approach to the mobility needs of older and disabled people (walking independently) are proposed. These decisions can provide benefits (spatial and economic savings). They fall into the "design for all" trend and sustainability of the built environment. These demands are based on no longer valid normative regulations. Med Pr Work Health Saf. 2024;75(3):189-197.

背景:建筑法》规定,在设计建筑环境时要考虑到不同年龄和心理生理能力的用户的需求。老年人和他们的空间需求在有限的范围内得到了考虑。设计的基准是轮椅使用者。与独立行走的人相比,包括大多数老年人在内,他们对空间的要求更高。这使得整个建筑环境很难适应行动不便者的需求。这可以从空间设计和投资成本的角度来考虑:本文从塑造老年人和残疾人建筑活动空间的法律条件方面分析了 3 个国家的建筑法规。本文采用了分析和比较方法。此类研究越来越具有现实意义和必要性。分析是在人口老龄化的背景下进行的。波兰社会各年龄段的统计数据为分析提供了依据。随后对轮椅活动空间的法律要求进行了设计分析,并提出了替代方案的建议,例如,使用手杖行走的人(案例研究)。其目的是指出限制建筑物中过多交流空间的方法,同时保持所有使用者的功能价值:研究结果:研究结果表明,有可能使法规和现行法律的替代品更加多样化。它们专门用于投资过程中的参与者,以塑造无障碍建筑。它们还可用于修订建筑法的立法工作:建议修改建筑法规,并针对老年人和残疾人的行动需求(独立行走)制定详细的方法。这些决定可以带来好处(节省空间和经济成本)。它们符合 "为所有人设计 "的趋势和建筑环境的可持续性。这些要求是基于不再有效的规范性规定。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
[Fatty liver as a risk factor for cardiovascular diseases: retrospective analysis of data from patients of the Geriatrics Clinic of University Clinical Hospital in Wrocław]. [脂肪肝是心血管疾病的风险因素:对弗罗茨瓦夫大学临床医院老年病诊所患者数据的回顾性分析]。
Pub Date : 2024-07-25 Epub Date: 2024-07-12 DOI: 10.13075/mp.5893.01510
Małgorzata Szymala-Pędzik, Marcin Piersiak, Maciej Pachana, Wojciech Tomczak, Małgorzata Izabela Sobieszczańska, Anna Janocha

Background: Non-alcoholic fatty liver disease (NAFLD) is currently the most common liver disorder affecting about 25% of the global population. The causes of its development include poor diet, low physical activity, overweight, obesity, older age, diabetes, and lipid disorders. Non-alcoholic fatty liver disease is identified by some researchers as a hepatic manifestation of metabolic syndrome. It has been observed that patients with NAFLD have an increased risk of cardiovascular events, as well as a higher number of deaths from myocardial infarction compared to the general population.

Material and methods: A retrospective analysis was conducted on the data of 237 patients diagnosed with hepatic steatosis, treated in the Department of Geriatrics at the University Clinical Hospital in Wrocław from 2019 to 2022, focusing on coexisting overweight, obesity, and concomitant diseases. Laboratory results and the degree of left ventricular muscle hypertrophy were analyzed. Parameters assessed by echocardiography, including interventricular septal thickness in diastole (IVSd), left ventricular posterior wall thickness in diastole (LVPWd), and IVSd + LVPWd/2, were used to evaluate left ventricular hypertrophy.

Results: Data from 237 patients were analyzed: 79 men (age: 77.2±7.1 years) and 158 women (age: 78.4±7.7 years). Body mass index (BMI) values for men and women were 30.5±5.0 kg/m² and 31.9±5.6 kg/m², respectively. There was a positive correlation between BMI and the degree of left ventricular hypertrophy for the parameters IVSd (ρ = 0.36, p < 0.001), LVPWd (ρ = 0.36, p < 0.001), and IVSd + LVPWd/2 (ρ = 0.38, p < 0.001).

Conclusions: The study demonstrated a moderate positive correlation between BMI and the degree of left ventricular hypertrophy in patients diagnosed with hepatic steatosis. These findings indicate the necessity of actively searching for cardiovascular risk factors, including the evaluation of echocardiographic parameters in patients with NAFLD. Med Pr Work Health Saf. 2024;75(3):223-231.

背景:非酒精性脂肪肝(NAFLD非酒精性脂肪肝(NAFLD)是目前最常见的肝脏疾病,影响着全球约 25% 的人口。其发病原因包括饮食不当、体力活动少、超重、肥胖、老年、糖尿病和血脂紊乱。一些研究人员认为,非酒精性脂肪肝是代谢综合征的一种肝脏表现形式。据观察,与普通人群相比,非酒精性脂肪肝患者发生心血管事件的风险更高,死于心肌梗死的人数也更多:对弗罗茨瓦夫大学临床医院老年病科在2019年至2022年期间收治的237名确诊为肝脂肪变性患者的数据进行了回顾性分析,重点关注同时存在的超重、肥胖和伴随疾病。对实验室结果和左心室肌肉肥厚程度进行了分析。超声心动图评估的参数包括舒张期室间隔厚度(IVSd)、舒张期左室后壁厚度(LVPWd)和IVSd + LVPWd/2,用于评估左心室肥厚:分析了 237 名患者的数据:79 名男性(年龄:77.2±7.1 岁)和 158 名女性(年龄:78.4±7.7 岁)。男性和女性的体重指数(BMI)值分别为 30.5±5.0 kg/m² 和 31.9±5.6 kg/m²。在IVSd(ρ = 0.36,p < 0.001)、LVPWd(ρ = 0.36,p < 0.001)和IVSd + LVPWd/2(ρ = 0.38,p < 0.001)参数中,体重指数与左心室肥厚程度呈正相关:研究表明,肝脂肪变性患者的体重指数与左心室肥厚程度呈中度正相关。这些发现表明,有必要积极寻找心血管风险因素,包括评估非酒精性脂肪肝患者的超声心动图参数。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
Assessment of qualitative body composition, including phase angle, in the context of primary prevention and secondary prevention of cardiovascular diseases (cardiac rehabilitation). 在心血管疾病的一级预防和二级预防(心脏康复)中,评估身体的定性组成,包括相位角。
Pub Date : 2024-07-25 Epub Date: 2024-06-24 DOI: 10.13075/mp.5893.01495
Aleksandra Ślązak, Małgorzata Paprocka-Borowicz

Cardiovascular diseases (CVDs) are one of the main causes of morbidity and disability worldwide. Due to modern methods of diagnosis and treatment, it is possible to protect patients with acute coronary syndromes from myocardial infarction as well from its early complications. However, the challenge remains to improve the long-term prognosis of CVDs. Analysis of body composition using the bioelectrical impedance (BIA) appears to be a good method for assessing changes in patients' organisms following various cardiac incidents, as well as those participating in rehabilitation programmes. This study aims to provide a complementary analysis of the scientific literature and a critical review of the data from the use of BIA to assess phase angle in people with a history of cardiac diseases. This critical literature review was prepared based on the Scale for the Assessment of Narrative Review Articles recommendations. Inclusion criteria included 1) original publications of a research nature, 2) papers indexed in PubMed, Scopus, Embase databases, 3) full-text articles in English, 4) recent papers published between 2013-2023, 5) papers on the use of BIA with phase angle assessment as a prognostic factor in multiple aspects of health and disease, 6) papers showing changes in body composition in the process of cardiac rehabilitation. Based on a review of PubMed, Scopus and Embase databases, 36, 31 and 114 publications were found, respectively, chosen on the basis of precisely selected keywords and included for further full-text analysis. Exploring the role of the BIA holds lots of hope as a non-invasive method that can be used as a predictive marker for changes in the state of health in various fields of medicine. In young, healthy adults, BIA parameters may be important in identifying risk factors for the development of particular diseases, in predicting the rapid development of disease symptoms and in promoting motivation to lifestyle changes. Med Pr Work Health Saf. 2024;75(3):243-254.

心血管疾病(CVDs)是全球发病率和致残率的主要原因之一。由于采用了现代诊断和治疗方法,急性冠状动脉综合征患者有可能避免心肌梗死及其早期并发症。然而,改善心血管疾病的长期预后仍然是一项挑战。使用生物电阻抗(BIA)分析身体成分似乎是一种很好的方法,可用于评估各种心脏事件后患者以及参与康复计划的患者的机体变化。本研究旨在对科学文献进行补充分析,并对使用生物电阻抗评估心脏病患者相位角的数据进行批判性回顾。本批判性文献综述是根据叙事性综述文章评估量表的建议编写的。纳入标准包括:1)研究性质的原始出版物;2)PubMed、Scopus、Embase 数据库收录的论文;3)全文英文文章;4)2013-2023 年间发表的最新论文;5)关于使用 BIA 相位角评估作为健康和疾病多方面预后因素的论文;6)显示心脏康复过程中身体成分变化的论文。根据对 PubMed、Scopus 和 Embase 数据库的审查,分别找到了 36、31 和 114 篇出版物,这些出版物都是根据精确选择的关键字筛选出来的,并纳入了进一步的全文分析。作为一种非侵入性方法,BIA 的作用探索充满希望,它可用作各医学领域健康状况变化的预测标志。在年轻、健康的成年人中,BIA 参数可能对确定特定疾病的发病风险因素、预测疾病症状的快速发展以及促进改变生活方式的积极性非常重要。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
[The possibility of fulfilling the needs of senior individuals through the activation of waterfront areas using mobile architectural-urban elements]. [利用移动建筑-城市元素激活滨水区,满足老年人需求的可能性]。
Pub Date : 2024-07-25 Epub Date: 2024-07-01 DOI: 10.13075/mp.5893.01519
Wacław Szarejko

Background: The aim of this article is to attempt to answer the question of how to enhance the fulfillment of needs for senior citizens residing in riverside cities. To achieve this, an attempt was made to develop the principles of a cohesive system that enables the activation of waterfront areas located in urbanized regions, often affected by a deficit of green spaces. The concept presented in this article is based on a consistent focus on architectural and urban design solutions that provide opportunities for functional enrichment of underutilized riverside areas for recreational purposes.

Material and methods: Based on literature studies, field research, and design analysis, this article demonstrates the possibility of taking a structural approach to implementing changes in the utilization of green spaces located by the water in contemporary cities. Using the results of the analysis, an original system called the mobile architectural-urban elements (mobilne elementy architektoniczno-urbanistyczne - MEAU) was developed to activate the untapped potential of waterfront areas to meet the specific needs of senior citizens.

Results: The research objective outlined in the introduction led to the development of a solution based on the utilization of floating architecture for the establishment of services and amenities that enable comfortable and diverse leisure activities for the elderly. Additionally, it was demonstrated that the described approach aligns with the multidimensional vision of improving the well-being of users, as defined by the European Commission in the New European Bauhaus (NEB) program.

Conclusions: The analysis conducted in this article allows for preliminary confirmation of the hypothesis that the specific needs of senior citizens can be fulfilled through the activation of waterfront areas using MEAU located on the water. Such actions not only activate existing resources but also align with the guidelines of the NEB idea, providing a coherent and applicable model with significant implementation potential for most waterfront cities. Med Pr Work Health Saf. 2024;75(3):211-222.

背景:本文旨在回答如何更好地满足居住在滨河城市的老年人的需求这一问题。为了实现这一目标,我们试图制定一个具有凝聚力的系统原则,以激活位于城市化地区的滨水区,这些地区往往受到绿地不足的影响。本文提出的概念基于对建筑和城市设计方案的持续关注,这些方案为丰富利用率不足的河滨地区的功能提供了机会,使其达到休闲娱乐的目的:本文以文献研究、实地调研和设计分析为基础,论证了采取结构性方法改变当代城市水边绿地利用方式的可能性。利用分析结果,开发了一个名为 "移动建筑-城市元素"(mobilne elementy architektonicznoo-urbanistyczne - MEAU)的原创系统,以激活滨水区尚未开发的潜力,满足老年人的特殊需求:结果:根据导言中概述的研究目标,开发了一个基于利用浮动建筑的解决方案,以建立服务和设施,为老年人提供舒适和多样化的休闲活动。此外,研究还表明,所述方法符合欧盟委员会在新欧洲包豪斯(NEB)计划中确定的改善用户福祉的多维愿景:本文所做的分析初步证实了一个假设,即通过利用水上的 MEAU 来激活滨水区域,可以满足老年人的特殊需求。这些行动不仅能激活现有资源,还符合国家环境预算理念的指导方针,为大多数滨水城市提供了一个具有巨大实施潜力的连贯而适用的模式。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
[Adaptations of the work environment facilitating the professional activity of seniors]. [调整工作环境,促进老年人的职业活动]。
Pub Date : 2024-07-10 DOI: 10.13075/mp.5893.01549
Bronisław Kapitaniak, Alicja Bortkiewicz

Background: Analysis of demographic trends indicates that there is an increasing proportion of people who can be described as elderly. In Poland, the population aged >60 years is expected to increase to 10.8 million in 2030 and to 13.7 million in 2050, i.e., around 40% of total population. In line with the general trend, the issue of the aging of the professionally active population is becoming more relevant.

Material and methods: The average age of the world's working population is steadily increasing. In the European Union, workers aged 55-64 years accounted for 50% of the total workforce in 2013, and already 59% in 2018. In Poland, in 2018, people aged 55-64 years accounted for 49% of the employed population. The low percentage of people working at this age is due, among other things, to employers' attitudes towards employing older people, perceiving them as employees who are more difficult to manage and have health problems. Moreover, working conditions of seniors are not adapted to their age capabilities.

Results: It is necessary to reduce the burden of physical work, especially in awkward positions, carrying loads, monotonous work and piecework. It is important to create work organization in which it is possible to refer to the experience of older people, who should have freedom of action, without time pressure and the need to perform many tasks at the same time. The ever-increasing social dependence on information technology tools creates new problems for seniors. Taking into account age-related difficulties in acquiring new knowledge, it is important to provide them with simplified tools that are easier to use.

Conclusions: The scope of necessary actions to enable the aging population to work is very wide, ranging from legislative, technological and organizational changes, ending with education addressed both to people responsible for employee safety (including occupational health services) and to current and potential employees. Med Pr Work Health Saf. 2024;75(3).

背景:对人口趋势的分析表明,老年人的比例越来越高。在波兰,年龄大于 60 岁的人口预计将在 2030 年增加到 1080 万,在 2050 年增加到 1370 万,即占总人口的 40%左右。根据这一总体趋势,职业活跃人口的老龄化问题正变得越来越重要:世界劳动人口的平均年龄正在稳步上升。在欧盟,55-64 岁的劳动力在 2013 年占总劳动力的 50%,2018 年已占 59%。在波兰,2018 年 55-64 岁的人口占就业人口的 49%。这个年龄段的就业人口比例较低的原因之一是雇主对雇用老年人的态度,认为他们是更难管理和有健康问题的员工。此外,老年人的工作条件也与其年龄能力不相适应:结果:有必要减轻体力劳动的负担,尤其是姿势笨拙、负重、单调的工作和计件工作。重要的是要建立能够参考老年人经验的工作组织,老年人应该有行动自由,没有时间压力,也不需要同时完成许多任务。社会对信息技术工具的依赖性越来越强,这给老年人带来了新的问题。考虑到老年人在获取新知识方面的困难,必须为他们提供更易于使用的简化工具:为使老龄人口能够工作而采取的必要行动范围非常广泛,包括立法、技术和组织变革,最后是对负责员工安全(包括职业健康服务)的人员以及现有和潜在员工进行教育。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
[The problem of increased vitamin D3 level in a group of patients hospitalized in a geriatrics clinic]. [老年病诊所住院病人维生素 D3 水平升高的问题]。
Pub Date : 2024-06-26 DOI: 10.13075/mp.5893.01517
Joanna Żórawska, Wioletta Szczepaniak

Background: Taking into account the multi-directional beneficial effects of vitamin D3 and its widespread deficiency, regular supplementation is recommended. However, more and more attention is being paid to the risk of overdose with supplemented vitamin D3 and the associated serious health consequences.

Material and methods: The concentration of 25-hydroxyvitamin D (25(OH)D) is a routine test recommended upon admission to the Geriatrics Clinic of Wroclaw Medical University. The aim of the study was to analyze the results from January 2018 to June 2023. Additionally, information on the reported symptoms, gender and age of people with an increased level of vitamin D3 was collected.

Results: Analyzing a group of 1400 patients, it was noted that within 5 years, vitamin D3 concentrations exceeding the recommended level were recorded in 7 patients, including 3 with toxic levels. All abnormal results occurred in women. The most frequently reported symptoms included general weakness, lower limbs and joint pain, sleep disorders, low mood. People with toxic concentrations reported dizziness. In seniors there is a gradual increase in vitamin D concentration and its deficiency is less common. Higher concentrations were recorded in the group of older seniors, and concentrations considered toxic occur in the population >74 years of age. Supplements and drugs with vitamin D are most often used without consulting a doctor, without determining the appropriate dose, or without assessing the concentration of 25(OH)D in the serum.

Conclusions: To prevent vitamin D deficiency in seniors, doses >4000 IU daily are not recommended. It is advisable to check all medications and supplements taken at each doctor's visit in terms of duplicating treatment with vitamin D. It is advisable to assess the status of vitamin D supply the concentration of 25(OH)D in order to select the appropriate dose. Assessment of 1,25-dihydroxyvitamin D concentration is recommended in cases of vitamin D toxicity. Med Pr Work Health Saf. 2024;75(3).

背景:考虑到维生素 D3 的多向有益作用及其普遍缺乏性,建议定期补充维生素 D3。然而,人们越来越关注补充维生素 D3 过量的风险以及相关的严重健康后果:25- 羟基维生素 D(25(OH)D)浓度是弗罗茨瓦夫医科大学老年病诊所建议入院时进行的常规检测。研究旨在分析 2018 年 1 月至 2023 年 6 月的结果。此外,还收集了维生素 D3 水平升高者的报告症状、性别和年龄等信息:在对1400名患者进行分析后发现,在5年内,有7名患者的维生素D3浓度超过了推荐水平,其中包括3名中毒患者。所有异常结果均发生在女性身上。最常报告的症状包括全身无力、下肢和关节疼痛、睡眠障碍、情绪低落。中毒者会出现头晕。老年人体内的维生素 D 浓度会逐渐升高,缺乏维生素 D 的情况并不常见。老年群体中的维生素 D 浓度较高,超过 74 岁的人群中的维生素 D 浓度被认为是有毒的。维生素 D 补充剂和药物的使用通常没有咨询医生,没有确定适当的剂量,也没有评估血清中 25(OH)D 的浓度:结论:为预防老年人维生素 D 缺乏症,不建议每天服用大于 4000 IU 的剂量。建议在每次就诊时检查所有服用的药物和补充剂,以避免重复使用维生素 D 治疗。在维生素 D 中毒的情况下,建议评估 1,25-二羟维生素 D 的浓度。Med Pr Work Health Saf.2024;75(3).
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引用次数: 0
[Risk assessment and toxicity effects of materials used during additive manufacturing with FDM technology]. [使用 FDM 技术进行增材制造时所用材料的风险评估和毒性影响]。
Pub Date : 2024-05-21 Epub Date: 2024-03-22 DOI: 10.13075/mp.5893.01486
Elżbieta Dobrzyńska, Luiza Chojnacka-Puchta, Dorota Sawicka, Piotr Sobiech, Tomasz Jankowski, Adrian Okołowicz, Małgorzata Szewczyńska

This paper discusses the potential of additive printing, the risks it poses to users' health (including 3D printer operators) and the effects of chemical substances released during the printing based on the available in vitro and in vivo studies. It was shown that substances emitted during printing with the commonly used acrylonitrile butadiene styrene filament in additive manufacturing might have carcinogenic, hepatotoxic and teratogenic effects, as well as toxic effect on the respiratory system. The latest research on the mechanism of formation of particles and volatile organic compounds during 3D printing, the parameters affecting their potential emission, and trends in reducing these hazards are indicated. The need for the design of more environmentally friendly and less emissive printing materials, as well as strategies for prevention and individual and collective protection measures are emphasized. Users of 3D printers should be familiar with all possible aspects of the threats associated with the printing process. Insufficient data on direct exposure to chemicals and particles released during the use of filaments makes it difficult to build awareness of safe working practices. Of particular concern is the health impact of emitted chemicals and particles from thermally treated materials in one of the most popular technologies for 3D printing, i.e., fused deposition modelling. Exposure of the users to, e.g., plasticizers added to filaments occurs through a variety of routes, by absorption through the skin, by inhalation or ingestion. Available epidemiological data, as well as current experimental works, indicate that such exposure is a high risk of cardiovascular diseases, atherosclerosis in adults, and cardiac problems and metabolic disorders in children. This review, by identifying potential risk factors, may contribute to reducing the health loss of printer users and improving working conditions and safety, especially in enterprises where additive manufacturing technology is used. Med Pr Work Health Saf. 2024;75(2):159-171.

本文根据现有的体外和体内研究,讨论了添加剂打印的潜力、对用户(包括 3D 打印机操作员)健康造成的风险以及打印过程中释放的化学物质的影响。研究表明,在增材制造中使用常用的丙烯腈-丁二烯-苯乙烯(ABS)长丝进行打印时释放的物质可能具有致癌、致肝毒和致畸作用,并对呼吸系统产生毒性影响。本文介绍了有关 3D 打印过程中颗粒和挥发性有机化合物(VOC)形成机理、影响其潜在排放的参数以及减少这些危害的趋势的最新研究。强调了设计更环保、排放更少的打印材料的必要性,以及预防战略和个人及集体保护措施。3D 打印机用户应熟悉与打印过程相关的威胁的所有可能方面。由于在使用长丝过程中直接接触化学品和颗粒的数据不足,因此很难建立安全工作方法的意识。尤其值得关注的是,在最流行的 3D 打印技术(即熔融沉积建模)中,热处理材料释放的化学品和微粒对健康的影响。用户会通过皮肤吸收、吸入或摄入等多种途径接触到添加到长丝中的增塑剂。现有的流行病学数据以及当前的实验工作表明,接触此类物质极易引发心血管疾病,成年人容易患动脉粥样硬化,而儿童则容易出现心脏问题和代谢紊乱。这篇综述通过确定潜在的风险因素,可能有助于减少打印机使用者的健康损失,改善工作条件和安全,尤其是在使用增材制造技术的企业中。Med Pr Work Health Saf.2024;75(2).
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引用次数: 0
Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells. 极低频电磁场(ELF-EMF)诱导透明细胞肾癌细胞基因表达和细胞因子分泌的改变
Pub Date : 2024-05-21 Epub Date: 2024-05-08 DOI: 10.13075/mp.5893.01476
Aleksandra Cios, Martyna Ciepielak, Krystyna Lieto, Damian Matak, Sławomir Lewicki, Małgorzata Palusińska, Wanda Stankiewicz, Łukasz Szymański

Background: The study aimed to investigate the influence of extremely low-frequency electromagnetic fields (ELF-EMF) on clear cell renal cell carcinoma (ccRCC) by assessing alterations in gene expression and the secretion of cytokines and chemokines.

Material and methods: Three ccRCC cell lines (786-O, 769-P, and CAKI-1) and a healthy HEK293 cell line were subjected to ELF-EMF exposure (frequency 50 Hz, magnetic field strength 4.5 mT) for 30 min daily for 5 days. The study examined the expression of ADAM28, NCAM1, and VEGFC genes, along with the secretion of 30 cytokines and chemokines.

Results: Notably, primary tumor-derived cell lines, but not those from metastatic sites, exhibited ADAM28 gene expression, which increased following ELF-EMF exposure. A statistically significant reduction in VEGFC gene expression was observed in 769-P cells after ELF-EMF exposure. Additionally, NCAM1 gene expression was upregulated in HEK293, 769-P, and 786-O cells, representing normal embryonic kidney cells and primary tumor cells, but not in CAKI-1 cells, which model metastatic sites. After EMF exposure, there was a statistically significant decrease in transforming growth factor β1 (TGF-β1) concentration in the cell culture supernatants of HEK293 and CAKI-1 cell lines, with no other significant changes in the secretion of tested cytokines.

Conclusions: Given the study's findings and available research, caution is warranted when drawing conclusions about the potential inhibitory effect of ELF-EMF on ccRCC progression. Standardization of experimental models is imperative when assessing the effects of EMF in a human context. Med Pr Work Health Saf. 2024;75(2):133-141.

研究背景本研究旨在通过评估基因表达和细胞因子及趋化因子分泌的变化,研究极低频电磁场(ELF-EMF)对透明细胞肾细胞癌(ccRCC)的影响:对三种 ccRCC 细胞系(786-O、769-P 和 CAKI-1)和一种健康的 HEK293 细胞系进行为期 5 天、每天 30 分钟的 ELF-EMF 暴露(频率 50 赫兹,磁场强度 4.5 mT)。研究检测了 ADAM28、NCAM1 和 VEGFC 基因的表达,以及 30 种细胞因子和趋化因子的分泌:结果:值得注意的是,原发性肿瘤细胞系(而非来自转移部位的细胞系)的ADAM28基因表达在暴露于ELF-EMF后有所增加。据统计,暴露于 ELF-EMF 后,769-P 细胞中的 VEGFC 基因表达明显减少。此外,在代表正常胚胎肾细胞和原发性肿瘤细胞的 HEK293、769-P 和 786-O 细胞中,NCAM1 基因表达上调,但在模拟转移部位的 CAKI-1 细胞中则没有上调。暴露于电磁场后,HEK293 和 CAKI-1 细胞系的细胞培养上清液中转化生长因子 β1(TGF-β1)的浓度出现了统计学意义上的显著下降,而测试细胞因子的分泌则没有其他显著变化:鉴于本研究的发现和现有的研究,在就 ELF-EMF 对 ccRCC 病程进展的潜在抑制作用得出结论时必须谨慎。在评估电磁场对人体的影响时,实验模型的标准化势在必行。
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引用次数: 0
The impact of inertial exercises performed in the workplace on shoulder muscles' strength and muscles' fatigue resistance in women with disabilities. 在工作场所进行惯性练习对残疾妇女肩部肌肉力量和肌肉抗疲劳能力的影响。
Pub Date : 2024-05-21 Epub Date: 2024-03-26 DOI: 10.13075/mp.5893.01503
Alicja Naczk, Wioletta Brzenczek-Owczarzak, Zdzisław Adach, Piotr Gramza, Justyna Forjasz, Ewa Gajewska, Mariusz Naczk

Background: Workers who do monotonous and repetitive work in a static position often complain about fatigue and decreased work efficiency. Some studies indicate that to improve muscle fatigue, resistance strength training can be used.

Material and methods: To investigate the effect of 4-week inertial training on shoulder muscles' strength and muscles' fatigue resistance 44 female workers with disabilities were examined. The participants were randomized into the training group (T) (N = 32) and the control group (C) (N = 12). Before the training and after that shoulder muscles' strength were tested at the start and at the end of the workday (Monday and Friday). The participants were asked to complete questionnaire concerning their fatigue at work (T and C), inertial training and work efficiency (T).

Results: The work performed during the last day of the workweek, i.e., Friday (before training) resulted in a significant decrease in shoulder muscles' strength in T and C. Muscle strength achieved at the end of the workweek (Friday afternoon) was significantly lower than achieved at the start of the workweek (Monday morning) in both tested groups (before training). Moreover, inertial training resulted in a significant increase in shoulder muscles' strength in T; 34-74% for different muscles. No changes in muscles' strength were noted in C. Increased muscle strength in T following inertial training effectively prevented muscle fatigue. After training the differences in shoulder muscles' strength noted in T during different times of the workday and workweek were insignificant. Moreover, 4-week inertial training increased significantly the work efficiency of women from T by 4%; no changes were noted in C. Inertial training was well tolerated by the participants.

Conclusions: Using inertial training in women with disabilities to prevent shoulder muscles' fatigue during the workday and workweek is recommended. Med Pr Work Health Saf. 2024;75(2):113-122.

背景:在静态姿势下从事单调重复工作的工人经常抱怨疲劳和工作效率下降。一些研究表明,要改善肌肉疲劳,可以进行抗阻力量训练:为了研究为期四周的惯性训练对肩部肌肉力量和肌肉抗疲劳能力的影响,44 名残疾女工接受了训练。参与者被随机分为训练组(T)(32 人)和对照组(C)(12 人)。训练前和训练后,分别在工作日(周一和周五)开始和结束时测试肩部肌肉力量。参与者被要求填写有关工作疲劳(T 组和 C 组)、惯性训练和工作效率(T 组)的问卷:在工作周的最后一天,即周五(训练前)进行的工作导致 T 和 C 的肩部肌肉力量显著下降。在工作周结束时(周五下午)达到的肌肉力量明显低于工作周开始时(周一上午)达到的力量。此外,惯性训练使 T 组的肩部肌肉力量明显增加;不同肌肉的增加幅度为 34-74%。惯性训练后,T 组肌肉力量的增加有效地防止了肌肉疲劳。训练后,T 在工作日和工作周的不同时间段的肩部肌肉力量差异并不明显。此外,为期 4 周的惯性训练使 T 组女性的工作效率显著提高了 4%;C 组则没有任何变化:结论:我们建议残疾妇女使用惯性训练来防止肩部肌肉在工作日和工作周内疲劳。Med Pr Work Health Saf.2024;75(2).
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引用次数: 0
[The relationships between recovery and teachers' exhaustion and performance: Mediational role of work-related self-efficacy]. [恢复与教师疲惫和绩效之间的关系:与工作相关的自我效能感的中介作用]。
Pub Date : 2024-05-17 DOI: 10.13075/mp.5893.01482
Łukasz Baka, Łukasz Kapica, Elżbieta Łastowiecka-Moras

Background: The aim of the study was to better understand the process through which recovery leads to teachers' exhaustion and performance. The direct and the indirect, i.e., mediated by teacher' work-related self-efficacy, effects of recovery on exhaustion and job performance were measured. To assessment of recovery, the Polish version of the Work-Related Rumination Scale (W-RRS) was developed. It measures detachment, affective rumination and problem-solving pondering. The psychometric properties of this tool constitute an additional contribution to the article.

Material and methods: The study was conducted among a group of primary and secondary school teachers (N = 503). The factor structure of the W-RRS scale was checked using confirmatory factor analysis (CFA), its reliability by using of Cronbach's α measure, and its theoretical validity by means of correlation of main variables with criterion variables. Hypotheses related to direct and mediation effects were verified using structural equation modeling (SEM).

Results: The obtained results confirmed the criterion and construct validity and reliability of the W-RRS. It has been also shown that detachment is directly negatively associated with exhaustion (but not with performance), affective rumination is a predictor of higher exhaustion and lower job performance, and problem-solving pondering is related to job performance (but not to exhaustion). Self-efficacy mediates the effect of 2 (out of the 3) types of recovery on exhaustion and job performance, such that high levels of problem-solving pondering and low levels of affective rumination translate into high self-efficacy, which in turn leads to lower exhaustion and higher job performance.

Conclusions: The recovery methods have various implications for functioning of teachers. While detachment and problem-solving pondering seem to promote it, affective rumination intensifies exhaustion and reduces performance. The mediator of the recovery-psychological well-being relationship is self-efficacy. The W-RRS questionnaire can be used to assessment of rumination among teachers.

背景:本研究旨在更好地了解恢复导致教师疲惫和工作表现的过程。研究测量了恢复对疲惫和工作表现的直接和间接影响,即在教师工作相关自我效能感的中介作用下,恢复对疲惫和工作表现的影响。为评估恢复情况,编制了波兰语版的工作相关遐想量表(W-RRS)。该量表用于测量脱离、情感反刍和问题解决思考。该工具的心理计量特性是本文的另一贡献:研究对象为中小学教师(503 人)。使用确认性因子分析(CFA)检验了 W-RRS 量表的因子结构,使用 Cronbach's α 测量了其可靠性,并通过主要变量与标准变量的相关性检验了其理论有效性。利用结构方程模型(SEM)验证了与直接效应和中介效应相关的假设:结果:所得结果证实了 W-RRS 的标准效度、建构效度和信度。研究还表明,疏离感与疲惫感直接呈负相关(但与工作绩效无关),情感反刍可预测较高的疲惫感和较低的工作绩效,问题解决思考与工作绩效相关(但与疲惫感无关)。自我效能感在三种恢复类型中的两种类型对精疲力竭和工作绩效的影响中起着中介作用,即高水平的问题解决思考和低水平的情感反刍转化为高水平的自我效能感,进而导致较低的精疲力竭和较高的工作绩效:恢复方法对教师的工作有不同的影响。超脱和解决问题的思考似乎能促进恢复,而情感反刍则会加剧疲惫,降低工作绩效。恢复-心理健康关系的中介是自我效能感。W-RRS问卷可用于评估教师的反刍。
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