首页 > 最新文献

Medycyna pracy最新文献

英文 中文
[Carcinogens and mutagens in Polish enterprises in 2022-2023]. 【2022-2023年波兰企业中的致癌物和诱变物】。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-02-26 DOI: 10.13075/mp.5893.01691
Katarzyna Konieczko, Agnieszka Klimecka, Karolina Jeżak, Stella Bujak-Pietrek, Joanna Jurewicz

Background: The aim of the study is to present information on the occurrence of carcinogenic or mutagenic agents in Polish enterprises in 2022-2023, based on information from the Central Register of Data on Exposure to Carcinogenic, Mutagenic or Reprotoxic Chemical Substances, Their Mixtures, Agents or Technological Processes (Centralny rejestr danych o narażeniu na substancje chemiczne, ich mieszaniny, czynniki lub procesy technologiczne o działaniu rakotwórczym, mutagennym lub reprotoksycznym - CRCR) maintained at the Nofer Institute of Occupational Medicine.

Material and methods: Employers who employ workers with carcinogenic, mutagenic, and, from 2024, also reprotoxic agents, are legally obliged to register such works. Information from voivodeships is submitted annually to the sanitary and labor inspection, and nationwide data are collected in the CRCR. The study used data for 2022-2023, collected and verified by the CRCR staff in 2023-2024. Data for groups of agents - chemical substances, physical factor - ionizing radiation, and technological processes - were also analyzed. Previous data (2005-2021) were used for comparison.

Results: In 2022-2023 data were collected from 14 500 and 17 100 enterprises. An increase also occurred for specific groups of agents - chemical substances, technological processes, and the only physical agent legally recognized as carcinogen and mutagen - ionizing radiation. The largest increase concerned technological processes - >26% (7653 and 9685 during the analyzed years). The most frequently reported were 2 technological processes - work involving exposure to wood dust and the respirable fraction of crystalline silica - followed by ionizing radiation and 2 chemical substances: unspecified low-boiling-point gasoline and formaldehyde.

Conclusions: The increase in the number of reports is due not only to economic and technological developments, but also to legal changes that have expanded the list of carcinogenic or mutagenic agents. The further extending the list of substances subject to the obligation to register in workplaces to include reprotoxic substances will result in a sharp increase in the number of notifications for 2024. Med Pr Work Health Saf. 2026;77(1):49-59.

背景:该研究的目的是根据致癌、致突变或生殖毒性化学物质、其混合物、制剂或工艺过程中央数据登记册(Centralny rejestr danych o narażeniu)的信息,提供2022-2023年波兰企业中致癌或致突变物质发生的信息。在诺弗职业医学研究所维护的突变体俱乐部生殖系统(CRCR)。材料和方法:从2024年起,雇用具有致癌性、诱变性和生殖毒性物质的工人的雇主有法律义务对此类工作进行登记。各省每年向卫生和劳动检查委员会提交信息,全国数据收集在CRCR中。该研究使用了2022-2023年的数据,由CRCR工作人员在2023-2024年收集和验证。还分析了药剂组的数据——化学物质、物理因素——电离辐射和工艺过程。以前的数据(2005-2021年)用于比较。结果:在2022-2023年共收集了14500家企业和17100家企业的数据。特定种类的药剂——化学物质、工艺过程和唯一被法律认定为致癌物和诱变剂的物理药剂——电离辐射——也出现了增加。最大的增长与技术过程有关,达到2626%(分析年份为7653和9685)。报告中最常见的是两种技术过程——涉及接触木屑和可吸入结晶二氧化硅的工作——其次是电离辐射和两种化学物质:未指明的低沸点汽油和甲醛。结论:报告数量的增加不仅是由于经济和技术的发展,也是由于法律的变化,扩大了致癌或致突变剂的清单。进一步扩大有义务在工作场所登记的物质清单,将生殖毒性物质包括在内,将导致2024年通知数量急剧增加。中国医学杂志,2009;27(1)。
{"title":"[Carcinogens and mutagens in Polish enterprises in 2022-2023].","authors":"Katarzyna Konieczko, Agnieszka Klimecka, Karolina Jeżak, Stella Bujak-Pietrek, Joanna Jurewicz","doi":"10.13075/mp.5893.01691","DOIUrl":"10.13075/mp.5893.01691","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study is to present information on the occurrence of carcinogenic or mutagenic agents in Polish enterprises in 2022-2023, based on information from the Central Register of Data on Exposure to Carcinogenic, Mutagenic or Reprotoxic Chemical Substances, Their Mixtures, Agents or Technological Processes (Centralny rejestr danych o narażeniu na substancje chemiczne, ich mieszaniny, czynniki lub procesy technologiczne o działaniu rakotwórczym, mutagennym lub reprotoksycznym - CRCR) maintained at the Nofer Institute of Occupational Medicine.</p><p><strong>Material and methods: </strong>Employers who employ workers with carcinogenic, mutagenic, and, from 2024, also reprotoxic agents, are legally obliged to register such works. Information from voivodeships is submitted annually to the sanitary and labor inspection, and nationwide data are collected in the CRCR. The study used data for 2022-2023, collected and verified by the CRCR staff in 2023-2024. Data for groups of agents - chemical substances, physical factor - ionizing radiation, and technological processes - were also analyzed. Previous data (2005-2021) were used for comparison.</p><p><strong>Results: </strong>In 2022-2023 data were collected from 14 500 and 17 100 enterprises. An increase also occurred for specific groups of agents - chemical substances, technological processes, and the only physical agent legally recognized as carcinogen and mutagen - ionizing radiation. The largest increase concerned technological processes - >26% (7653 and 9685 during the analyzed years). The most frequently reported were 2 technological processes - work involving exposure to wood dust and the respirable fraction of crystalline silica - followed by ionizing radiation and 2 chemical substances: unspecified low-boiling-point gasoline and formaldehyde.</p><p><strong>Conclusions: </strong>The increase in the number of reports is due not only to economic and technological developments, but also to legal changes that have expanded the list of carcinogenic or mutagenic agents. The further extending the list of substances subject to the obligation to register in workplaces to include reprotoxic substances will result in a sharp increase in the number of notifications for 2024. Med Pr Work Health Saf. 2026;77(1):49-59.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"49-59"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Patient's criminal liability for providing false medical information in the procedure for applying for a driving license]. 【患者在办理驾驶证过程中提供虚假医疗信息的刑事责任】。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-02-12 DOI: 10.13075/mp.5893.01666
Marcin Rybacki, Rafał Kubiak

The case report concerns a patient who, during a medical examination conducted to asses medical fitness to drive motor vehicles, concealed the truth about his health condition. Particular attention was paid to the discussion of the patient's responsibility for the content of information provided in the interview. The article discusses criminal liability for making a false statement, for obtaining false certification by fraud and for using a document obtained by fraud. Attention was also drawn to the social obligation to denounce, which may also apply to physicians involved in medical certification. In case of medical examinations of drivers, every patient has a legal and moral obligation to provide the physician with truthful and complete information about his/her health, medications, past illnesses, and lifestyle. Providing false information or concealing important information can lead to an incorrect final diagnosis and, consequently, an incorrect decision, which can endanger the health and life of not only the driver but also other road users. Med Pr Work Health Saf. 2026;77(1):71-80.

该病例报告涉及一名病人,他在进行体检以评估是否适合驾驶机动车时隐瞒了他健康状况的真相。特别注意的是讨论患者对访谈中提供的信息内容的责任。本文论述了作虚假陈述、欺诈取得虚假证明和使用欺诈取得的文书的刑事责任。还提请注意谴责的社会义务,这也可能适用于参与医疗证明的医生。在对司机进行体检的情况下,每个病人都有法律和道德义务向医生提供关于他/她的健康、药物、过去的疾病和生活方式的真实和完整的信息。提供虚假信息或隐瞒重要信息可能导致不正确的最终诊断,从而导致不正确的决定,这不仅会危及司机的健康和生命,也会危及其他道路使用者的健康和生命。中国医学杂志,2009;27(1)。
{"title":"[Patient's criminal liability for providing false medical information in the procedure for applying for a driving license].","authors":"Marcin Rybacki, Rafał Kubiak","doi":"10.13075/mp.5893.01666","DOIUrl":"10.13075/mp.5893.01666","url":null,"abstract":"<p><p>The case report concerns a patient who, during a medical examination conducted to asses medical fitness to drive motor vehicles, concealed the truth about his health condition. Particular attention was paid to the discussion of the patient's responsibility for the content of information provided in the interview. The article discusses criminal liability for making a false statement, for obtaining false certification by fraud and for using a document obtained by fraud. Attention was also drawn to the social obligation to denounce, which may also apply to physicians involved in medical certification. In case of medical examinations of drivers, every patient has a legal and moral obligation to provide the physician with truthful and complete information about his/her health, medications, past illnesses, and lifestyle. Providing false information or concealing important information can lead to an incorrect final diagnosis and, consequently, an incorrect decision, which can endanger the health and life of not only the driver but also other road users. Med Pr Work Health Saf. 2026;77(1):71-80.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"71-80"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors of occupational injuries and prevention strategy among Chinese frontline firefighters. 我国一线消防人员职业伤害危险因素及预防对策
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-02-10 DOI: 10.13075/mp.5893.01663
Qiang Song, Xinyu Gu

Background: Occupational injuries among firefighters significantly impact their job performance. To reduce these injuries and enhance their professional capabilities, this study investigates and comprehensively evaluates the factors contributing to occupational injuries among frontline firefighters in China. It analyzes the underlying mechanisms of these injuries and proposes preventive strategies.

Material and methods: This study employed questionnaire surveys and factor analysis methods to conduct a comprehensive investigation and comprehensive assessment of occupational injuries and their influencing factors among 200 firefighters in China. The research subjects were randomly selected from the grassroots firefighters in cities of FuJian Province. Among them, 179 firefighters successfully completed the questionnaire survey. Through exploratory factor analysis, the key factors influencing firefighters' injuries were identified.

Results: The injury rate among the participating firefighters in 2023 was 40.78%. The highest injury rate was observed during daily training (58.52%). Notably, the injury rate tends to decrease with increasing age. The most common types of injuries were sprains and strains (57.10%), with the knee joint exhibiting the highest incidence of injury among all body parts (47.00%). The primary factors influencing occupational injuries among firefighters include training factors, support factors, educational factors, and mental health factors, which collectively account for a variance contribution rate of 79.56%.

Conclusions: Training, support, educational, and mental health factors are the 4 primary influences on firefighters' occupational injuries. The administrative department should strengthen the study and practice of physical fitness theory for firefighters, prioritize the prevention of occupational training injuries, enhance the scientific rigor of training programs, and promote the occupational health of firefighters. Med Pr Work Health Saf. 2026;77(1):1-10.

背景:消防员职业伤害对其工作绩效有显著影响。为了减少这些伤害,提高他们的专业能力,本研究对中国一线消防员职业伤害的影响因素进行了调查和综合评估。它分析了这些损伤的潜在机制,并提出了预防策略。材料与方法:本研究采用问卷调查法和因子分析法,对全国200名消防队员职业伤害及其影响因素进行全面调查和综合评价。研究对象从福建省各城市基层消防队员中随机抽取。其中179名消防队员成功完成问卷调查。通过探索性因子分析,找出影响消防员受伤的关键因素。结果:2023年参加消防人员受伤率为40.78%。日常训练损伤率最高(58.52%)。损伤率随年龄的增长呈下降趋势。最常见的损伤类型为扭伤和拉伤(57.10%),其中膝关节损伤发生率最高(47.00%)。影响消防员职业伤害的主要因素为培训因素、支持因素、教育因素和心理健康因素,方差贡献率为79.56%。结论:培训、支持、教育和心理健康因素是影响消防员职业伤害的4个主要因素。行政管理部门要加强消防队员体能理论的学习和实践,把预防职业训练损伤放在首位,提高训练方案的科学性和严谨性,促进消防队员的职业健康。中国医学杂志,2009;27(1)。
{"title":"Risk factors of occupational injuries and prevention strategy among Chinese frontline firefighters.","authors":"Qiang Song, Xinyu Gu","doi":"10.13075/mp.5893.01663","DOIUrl":"10.13075/mp.5893.01663","url":null,"abstract":"<p><strong>Background: </strong>Occupational injuries among firefighters significantly impact their job performance. To reduce these injuries and enhance their professional capabilities, this study investigates and comprehensively evaluates the factors contributing to occupational injuries among frontline firefighters in China. It analyzes the underlying mechanisms of these injuries and proposes preventive strategies.</p><p><strong>Material and methods: </strong>This study employed questionnaire surveys and factor analysis methods to conduct a comprehensive investigation and comprehensive assessment of occupational injuries and their influencing factors among 200 firefighters in China. The research subjects were randomly selected from the grassroots firefighters in cities of FuJian Province. Among them, 179 firefighters successfully completed the questionnaire survey. Through exploratory factor analysis, the key factors influencing firefighters' injuries were identified.</p><p><strong>Results: </strong>The injury rate among the participating firefighters in 2023 was 40.78%. The highest injury rate was observed during daily training (58.52%). Notably, the injury rate tends to decrease with increasing age. The most common types of injuries were sprains and strains (57.10%), with the knee joint exhibiting the highest incidence of injury among all body parts (47.00%). The primary factors influencing occupational injuries among firefighters include training factors, support factors, educational factors, and mental health factors, which collectively account for a variance contribution rate of 79.56%.</p><p><strong>Conclusions: </strong>Training, support, educational, and mental health factors are the 4 primary influences on firefighters' occupational injuries. The administrative department should strengthen the study and practice of physical fitness theory for firefighters, prioritize the prevention of occupational training injuries, enhance the scientific rigor of training programs, and promote the occupational health of firefighters. Med Pr Work Health Saf. 2026;77(1):1-10.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"1-10"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intentional use of harmful biological agents in workplaces in Poland]. [波兰工作场所故意使用有害生物制剂]。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-03-09 DOI: 10.13075/mp.5893.01681
Anna Kozajda, Emilia Miśkiewicz, Joanna Jurewicz

Background: The work is a report on the intentional use of harmful biological agents in workplaces in Poland based on National Register of Biological Agents (Krajowy Rejestr Czynników Biologicznych - KRCB) as of June 2025.

Material and methods: The KRCB is a central database gathering notifications of the intentional use of biological agents in risk groups 2-4 in work processes in accordance with the Regulation of the Minister of Health of December 11, 2020, amending the regulation regarding biological agents.

Results: Notifications were sent by 749 enterprises for: diagnostic - 59.3%, research - 32.4% and industrial purposes - 8.1%. Notifications were most often sent by microbial laboratories (N = 438, 58.5%), scientific-research institutions (N = 229, 30.6%) and industrial enterprises (N = 82, 11.0%). In total, 7795 workers (87.6% women, 12.4% men) were exposed to biological agents intentionally used at work. Biological agents from risk groups 2 and 3 were used by 97.6% and 15.9% enterprises, respectively. The most frequently were used bacteria Escherichia coli (with the exception of non-pathogenic strains) - 4823 exposed workers (61.9%), Staphylococcus aureus - respectively 4655 (59.7%) and Pseudomonas aeruginosa - 4188 (53.7%). National Register of Biological Agents gathered 9 notifications of intentionally using of the biological agent carcinogenic to humans, including viruses (hepatitis B virus [N = 2015 workers, 25.8%], hepatitis C virus [N = 1982, 25.4%], human immunodeficiency virus type 1 [N = 1796, 22.7%], Epstein-Barr virus [N = 196, 2.5%], human papilloma virus [N = 60, 0.8%], human herpes virus type 8 [N = 16, 0.2%], human T-lymphotropic virus type 1 [N = 38, 0.5%]), bacteria (Helicobacter pylori [N = 327, 4.2%]), parasite (Schistosoma haematobium [N = 9, 0.1%]).

Conclusions: Intentionally used biological agents most often pose a threat to workers of microbial laboratories, but a higher health risk concerns workers of scientific-research institutions. Med Pr Work Health Saf. 2026;77(1):11-26.

背景:这项工作是一份关于波兰工作场所故意使用有害生物制剂的报告,基于截至2025年6月的国家生物制剂登记册(Krajowy Rejestr Czynników Biologicznych - KRCB)。材料和方法:KRCB是一个中央数据库,根据2020年12月11日卫生部关于修订生物制剂法规的条例,收集关于在工作过程中故意在2-4风险组中使用生物制剂的通知。结果:749家企业发出诊断通知占59.3%,研究通知占32.4%,工业通知占8.1%。微生物实验室(N = 438, 58.5%)、科研机构(N = 229, 30.6%)和工业企业(N = 82, 11.0%)是发送通报最多的单位。总共有7795名工人(87.6%为女性,12.4%为男性)暴露于工作中故意使用的生物制剂。97.6%的企业使用风险组2和风险组3的生物制剂,15.9%的企业使用风险组3的生物制剂。最常用的细菌是大肠杆菌(非致病性菌株除外)4823例(61.9%)、金黄色葡萄球菌4655例(59.7%)和铜绿假单胞菌4188例(53.7%)。国家生物制剂聚集9通知故意使用生物制剂的致癌,包括病毒(乙型肝炎病毒(N = 2015员工中,有25.8%),丙型肝炎病毒(N = 1982, 25.4%),人类免疫缺陷病毒1型(N = 1796, 22.7%),巴尔病毒(N = 196, 2.5%),人类乳头状瘤病毒(N = 60, 0.8%),人类疱疹病毒8型(N = 16, 0.2%),人类t细胞白血病病毒1型(N = 38, 0.5%))、细菌(幽门螺杆菌(N = 327,4.2%]),寄生虫(血血吸虫[N = 9, 0.1%])。结论:故意使用生物制剂最常对微生物实验室工作人员构成威胁,但科研机构工作人员的健康风险更高。中国医学杂志,2009;27(1)。
{"title":"[Intentional use of harmful biological agents in workplaces in Poland].","authors":"Anna Kozajda, Emilia Miśkiewicz, Joanna Jurewicz","doi":"10.13075/mp.5893.01681","DOIUrl":"10.13075/mp.5893.01681","url":null,"abstract":"<p><strong>Background: </strong>The work is a report on the intentional use of harmful biological agents in workplaces in Poland based on National Register of Biological Agents (Krajowy Rejestr Czynników Biologicznych - KRCB) as of June 2025.</p><p><strong>Material and methods: </strong>The KRCB is a central database gathering notifications of the intentional use of biological agents in risk groups 2-4 in work processes in accordance with the Regulation of the Minister of Health of December 11, 2020, amending the regulation regarding biological agents.</p><p><strong>Results: </strong>Notifications were sent by 749 enterprises for: diagnostic - 59.3%, research - 32.4% and industrial purposes - 8.1%. Notifications were most often sent by microbial laboratories (N = 438, 58.5%), scientific-research institutions (N = 229, 30.6%) and industrial enterprises (N = 82, 11.0%). In total, 7795 workers (87.6% women, 12.4% men) were exposed to biological agents intentionally used at work. Biological agents from risk groups 2 and 3 were used by 97.6% and 15.9% enterprises, respectively. The most frequently were used bacteria <i>Escherichia coli</i> (with the exception of non-pathogenic strains) - 4823 exposed workers (61.9%), <i>Staphylococcus aureus</i> - respectively 4655 (59.7%) and <i>Pseudomonas aeruginosa</i> - 4188 (53.7%). National Register of Biological Agents gathered 9 notifications of intentionally using of the biological agent carcinogenic to humans, including viruses (hepatitis B virus [N = 2015 workers, 25.8%], hepatitis C virus [N = 1982, 25.4%], human immunodeficiency virus type 1 [N = 1796, 22.7%], Epstein-Barr virus [N = 196, 2.5%], human papilloma virus [N = 60, 0.8%], human herpes virus type 8 [N = 16, 0.2%], human T-lymphotropic virus type 1 [N = 38, 0.5%]), bacteria (<i>Helicobacter pylori</i> [N = 327, 4.2%]), parasite (<i>Schistosoma haematobium</i> [N = 9, 0.1%]).</p><p><strong>Conclusions: </strong>Intentionally used biological agents most often pose a threat to workers of microbial laboratories, but a higher health risk concerns workers of scientific-research institutions. Med Pr Work Health Saf. 2026;77(1):11-26.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"11-26"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147392121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational exposure to wood dust - legal aspects and preventive strategies. 职业接触木屑的法律方面和预防策略。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-02-27 DOI: 10.13075/mp.5893.01668
Alina Mroczek, Janusz Kasperczyk

Occupational exposure to wood dust is a major public health and occupational safety concern, particularly in woodworking, furniture production, and the wood-based materials industry. Its carcinogenic, allergenic, and toxic potential depends on wood species, physicochemical properties, processing methods, and applied chemical treatments. The aim of this review was to analyze occupational exposure to wood dust by synthesizing current evidence on worker health risks, measurement methods, legal regulations, and preventive strategies, in order to evaluate the adequacy of existing solutions and identify areas requiring further improvement. The review is based on 61 literature sources: publications, legal acts, official guidelines from international and national institutions (International Agency for Research on Cancer, National Institute for Occupational Safety and Health, Occupational Safety and Health Administration, American Conference of Governmental Industrial Hygienists, European Agency for Safety and Health at Work, Statistics Poland, Nofer Institute of Occupational Medicine, Polish Ministry of Health). Sources published 2010-2024 were analyzed with particular focus on dust characteristics, exposure limits, measurement methods, preventive measures, and regulatory frameworks. Exposure to wood dust contributes to both acute and chronic respiratory conditions, skin and eye irritation, and a higher incidence of upper respiratory tract cancers. Recent regulatory changes have expanded the classification of wood dust as a carcinogen to include all species. Despite existing occupational exposure limits (OELs), exceedances remain common in woodworking industries. Conventional monitoring methods may underestimate respirable and ultrafine particles (UFP <100 nm), which pose substantial health risks. Preventive strategies - including technical controls, ventilation, personal protective equipment, and medical surveillance - significantly reduce airborne dust concentrations and worker exposure. Findings indicate a need to update OELs and harmonize regulations with current scientific evidence. Effective prevention requires integrating legal requirements, engineering controls, process automation, and medical and educational interventions. Strengthening national standards within the European Union regulatory framework and improving measurement methods - especially for inhalable and ultrafine fractions - are essential to ensuring adequate worker protection. Med Pr Work Health Saf. 2026;77(1):61-70.

职业接触木尘是一个主要的公共卫生和职业安全问题,特别是在木工、家具生产和木基材料工业。其致癌性、致敏性和毒性取决于木材的种类、理化性质、加工方法和应用的化学处理。本次审查的目的是通过综合目前有关工人健康风险、测量方法、法律法规和预防战略的证据,分析木尘职业暴露,以评价现有解决办法的充足性并确定需要进一步改进的领域。该审查基于61个文献来源:出版物、法律行为、国际和国家机构(国际癌症研究机构、国家职业安全与健康研究所、职业安全与健康管理局、美国政府工业卫生学家会议、欧洲工作安全与健康机构、波兰统计局、诺弗职业医学研究所、波兰卫生部)的官方指南。对2010-2024年发布的来源进行了分析,特别关注粉尘特征、暴露限值、测量方法、预防措施和监管框架。接触木屑会导致急性和慢性呼吸道疾病、皮肤和眼睛受到刺激,并增加上呼吸道癌症的发病率。最近的监管变化扩大了木尘作为致癌物的分类,包括所有种类。尽管现有的职业暴露限值(OELs),超标仍然普遍存在于木工行业。传统的监测方法可能低估了可吸入颗粒物和超细颗粒物(UFP < 100 nm),它们对健康构成重大风险。预防战略——包括技术控制、通风、个人防护装备和医疗监测——可显著降低空气中的粉尘浓度和工人接触。研究结果表明,需要更新OELs并使法规与当前的科学证据相协调。有效的预防需要整合法律要求、工程控制、过程自动化以及医疗和教育干预。加强欧盟监管框架内的国家标准和改进测量方法——特别是可吸入和超细组分——对于确保充分保护工人至关重要。中国医学杂志,2009;27(1)。
{"title":"Occupational exposure to wood dust - legal aspects and preventive strategies.","authors":"Alina Mroczek, Janusz Kasperczyk","doi":"10.13075/mp.5893.01668","DOIUrl":"10.13075/mp.5893.01668","url":null,"abstract":"<p><p>Occupational exposure to wood dust is a major public health and occupational safety concern, particularly in woodworking, furniture production, and the wood-based materials industry. Its carcinogenic, allergenic, and toxic potential depends on wood species, physicochemical properties, processing methods, and applied chemical treatments. The aim of this review was to analyze occupational exposure to wood dust by synthesizing current evidence on worker health risks, measurement methods, legal regulations, and preventive strategies, in order to evaluate the adequacy of existing solutions and identify areas requiring further improvement. The review is based on 61 literature sources: publications, legal acts, official guidelines from international and national institutions (International Agency for Research on Cancer, National Institute for Occupational Safety and Health, Occupational Safety and Health Administration, American Conference of Governmental Industrial Hygienists, European Agency for Safety and Health at Work, Statistics Poland, Nofer Institute of Occupational Medicine, Polish Ministry of Health). Sources published 2010-2024 were analyzed with particular focus on dust characteristics, exposure limits, measurement methods, preventive measures, and regulatory frameworks. Exposure to wood dust contributes to both acute and chronic respiratory conditions, skin and eye irritation, and a higher incidence of upper respiratory tract cancers. Recent regulatory changes have expanded the classification of wood dust as a carcinogen to include all species. Despite existing occupational exposure limits (OELs), exceedances remain common in woodworking industries. Conventional monitoring methods may underestimate respirable and ultrafine particles (UFP <100 nm), which pose substantial health risks. Preventive strategies - including technical controls, ventilation, personal protective equipment, and medical surveillance - significantly reduce airborne dust concentrations and worker exposure. Findings indicate a need to update OELs and harmonize regulations with current scientific evidence. Effective prevention requires integrating legal requirements, engineering controls, process automation, and medical and educational interventions. Strengthening national standards within the European Union regulatory framework and improving measurement methods - especially for inhalable and ultrafine fractions - are essential to ensuring adequate worker protection. Med Pr Work Health Saf. 2026;77(1):61-70.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"61-70"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Assessment of pain and postural defects among young adults playing the violin]. [对演奏小提琴的年轻人疼痛和姿势缺陷的评估]。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-02-23 DOI: 10.13075/mp.5893.01695
Beata Stach, Emilia Bieńko, Anna Pilch, Małgorzata Jekiełek

Background: Violin playing involves prolonged upper limb exertion and asymmetrical posture, potentially leading to pain and postural defects. Despite the known prevalence of playing-related musculoskeletal disorders, data on young adult violinists compared to a control group remains insufficient. The aim of this study was to assess pain and postural problems among young adult violin players, and to compare them with those of non-violin players. Additionally, an attempt was made to identify the causes of these problems in violinists and to indicate directions that should be developed in further research.

Material and methods: The study included 50 participants (25 violinists and 25 individuals in the control group). A custom questionnaire was used to assess pain (Numerical Pain Rating Scale - NPRS), along with postural assessment based on the Kasperczyk method. Statistical analysis was conducted using the Mann-Whitney U test, chi-squared test, and Spearman's correlation coefficient.

Results: In the group of violinists, pain occurred significantly more frequently in the trapezius muscle (left: 68%, p = 0.0006; right: 52%, p = 0.0169) and the left shoulder (36%, p = 0.0405). The average pain intensity (NPRS) was significantl higher in the study group than in the control group (6.6 pts vs. 4.7 pts, p = 0.0085). In terms of posture, violinists scored significantly higher on the Kasperczyk assessment (M = 9.8 pts vs. M = 6.1 pts, p = 0.0002), indicating more postural abnormalities. The most common defects in this group included forward head posture, shoulder asymmetry, and foot flattening/valgus. Additionally, 88% of violinists reported that pain interfered with their ability to play in the past week.

Conclusions: Playing the violin is associated with an increased risk of musculoskeletal pain and postural abnormalities, particularly in the upper body. The results highlight the need for preventive strategies among musicians. The collected data may serve as a foundation for implementing preventive programs in music education, which should be continued into the violinist's later professional career. The data serve as a starting point for further research. Med Pr Work Health Saf. 2026;77(1):27-48.

背景:小提琴演奏需要长时间的上肢用力和不对称的姿势,可能导致疼痛和姿势缺陷。尽管已知与演奏相关的肌肉骨骼疾病普遍存在,但与对照组相比,年轻成年小提琴手的数据仍然不足。本研究的目的是评估年轻成年小提琴手的疼痛和姿势问题,并将其与非小提琴手进行比较。此外,还试图找出小提琴家出现这些问题的原因,并指出进一步研究应发展的方向。材料和方法:该研究包括50名参与者(25名小提琴手和25名对照组)。采用自定义问卷(数值疼痛评定量表- NPRS)评估疼痛,并根据kasperzyk方法进行体位评估。采用Mann-Whitney U检验、卡方检验和Spearman相关系数进行统计分析。结果:小提琴组中斜方肌(左:68%,p = 0.0006;右:52%,p = 0.0169)和左肩(36%,p = 0.0405)疼痛发生率明显高于小提琴组。研究组的平均疼痛强度(NPRS)明显高于对照组(6.6分对4.7分,p = 0.0085)。在姿势方面,小提琴手在kasperzyk评估中的得分明显更高(M = 9.8分对M = 6.1分,p = 0.0002),表明更多的姿势异常。该组中最常见的畸形包括前倾头位、肩部不对称和足部扁平/外翻。此外,88%的小提琴手报告说,在过去的一周里,疼痛影响了他们的演奏能力。结论:拉小提琴与肌肉骨骼疼痛和姿势异常的风险增加有关,特别是在上半身。研究结果强调了音乐家预防策略的必要性。收集到的数据可以作为在音乐教育中实施预防方案的基础,这些方案应该持续到小提琴家以后的职业生涯中。这些数据可以作为进一步研究的起点。中国医学杂志,2009;27(1)。
{"title":"[Assessment of pain and postural defects among young adults playing the violin].","authors":"Beata Stach, Emilia Bieńko, Anna Pilch, Małgorzata Jekiełek","doi":"10.13075/mp.5893.01695","DOIUrl":"10.13075/mp.5893.01695","url":null,"abstract":"<p><strong>Background: </strong>Violin playing involves prolonged upper limb exertion and asymmetrical posture, potentially leading to pain and postural defects. Despite the known prevalence of playing-related musculoskeletal disorders, data on young adult violinists compared to a control group remains insufficient. The aim of this study was to assess pain and postural problems among young adult violin players, and to compare them with those of non-violin players. Additionally, an attempt was made to identify the causes of these problems in violinists and to indicate directions that should be developed in further research.</p><p><strong>Material and methods: </strong>The study included 50 participants (25 violinists and 25 individuals in the control group). A custom questionnaire was used to assess pain (<i>Numerical Pain Rating Scale</i> - NPRS), along with postural assessment based on the Kasperczyk method. Statistical analysis was conducted using the Mann-Whitney U test, chi-squared test, and Spearman's correlation coefficient.</p><p><strong>Results: </strong>In the group of violinists, pain occurred significantly more frequently in the trapezius muscle (left: 68%, p = 0.0006; right: 52%, p = 0.0169) and the left shoulder (36%, p = 0.0405). The average pain intensity (NPRS) was significantl higher in the study group than in the control group (6.6 pts vs. 4.7 pts, p = 0.0085). In terms of posture, violinists scored significantly higher on the Kasperczyk assessment (M = 9.8 pts vs. M = 6.1 pts, p = 0.0002), indicating more postural abnormalities. The most common defects in this group included forward head posture, shoulder asymmetry, and foot flattening/valgus. Additionally, 88% of violinists reported that pain interfered with their ability to play in the past week.</p><p><strong>Conclusions: </strong>Playing the violin is associated with an increased risk of musculoskeletal pain and postural abnormalities, particularly in the upper body. The results highlight the need for preventive strategies among musicians. The collected data may serve as a foundation for implementing preventive programs in music education, which should be continued into the violinist's later professional career. The data serve as a starting point for further research. Med Pr Work Health Saf. 2026;77(1):27-48.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"27-48"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Caplan's syndrome - rare pneumoconioses in clinical practice: case report]. [卡普兰综合征-临床罕见尘肺病1例报告]。
IF 0.9 Pub Date : 2026-03-12 Epub Date: 2026-03-09 DOI: 10.13075/mp.5893.01654
Monika Najder-Gawlik, Marta Wiszniewska

Pneumoconioses are among the most frequently diagnosed occupational diseases in Poland, with collagenous pneumoconiosis forming a significant subgroup. These diseases develop as a result of exposure to fibrogenic dusts. One of the rare forms of such conditions is Caplan's syndrome - a rheumatoid type of pneumoconiosis characterized by the coexistence of pulmonary nodular lesions and rheumatoid arthritis. This condition is rarely diagnosed, most commonly among individuals occupationally exposed to silicate dust, such as coal miners. This article presents a case of a men with Caplan's syndrome qualified as occupational background just in the second instance of medical certification. A thorough re-evaluation of the patient's occupational and medical history confirmed a causal relationship between the development of the disease and exposure to silicate dust in his profession as a dental technician. This case highlights the diagnostic challenges resulting from the common misconception that Caplan's syndrome occurs exclusively in coal miners, whereas the risk extends to various occupational groups exposed to silicate dust. The described case underscores the importance of a comprehensive approach to clinical and occupational assessment in the diagnosis of pneumoconioses, particularly in the context of rare disease entities. Med Pr Work Health Saf. 2026;77(1):81-88.

尘肺病是波兰最常诊断的职业病之一,其中胶原性尘肺病是一个重要的亚组。这些疾病是由于接触纤维性粉尘而产生的。其中一种罕见的形式是卡普兰综合征——一种以肺结节病变和类风湿性关节炎共存为特征的类风湿型尘肺病。这种情况很少被诊断出来,最常见于职业暴露于硅酸盐粉尘的个体,如煤矿工人。这篇文章提出了一个男子卡普兰综合症合格的职业背景,只是在医疗认证的第二次实例。对病人的职业和病史进行了彻底的重新评估,证实了该疾病的发展与他作为牙科技术员在职业中接触硅酸盐粉尘之间存在因果关系。本病例强调了由于普遍的误解导致的诊断挑战,即卡普兰综合征仅发生在煤矿工人中,而风险延伸到暴露于硅酸盐粉尘的各种职业群体。所描述的病例强调了在尘肺病诊断中,特别是在罕见疾病实体的背景下,临床和职业评估综合方法的重要性。中国医学杂志,2009;27(1)。
{"title":"[Caplan's syndrome - rare pneumoconioses in clinical practice: case report].","authors":"Monika Najder-Gawlik, Marta Wiszniewska","doi":"10.13075/mp.5893.01654","DOIUrl":"10.13075/mp.5893.01654","url":null,"abstract":"<p><p>Pneumoconioses are among the most frequently diagnosed occupational diseases in Poland, with collagenous pneumoconiosis forming a significant subgroup. These diseases develop as a result of exposure to fibrogenic dusts. One of the rare forms of such conditions is Caplan's syndrome - a rheumatoid type of pneumoconiosis characterized by the coexistence of pulmonary nodular lesions and rheumatoid arthritis. This condition is rarely diagnosed, most commonly among individuals occupationally exposed to silicate dust, such as coal miners. This article presents a case of a men with Caplan's syndrome qualified as occupational background just in the second instance of medical certification. A thorough re-evaluation of the patient's occupational and medical history confirmed a causal relationship between the development of the disease and exposure to silicate dust in his profession as a dental technician. This case highlights the diagnostic challenges resulting from the common misconception that Caplan's syndrome occurs exclusively in coal miners, whereas the risk extends to various occupational groups exposed to silicate dust. The described case underscores the importance of a comprehensive approach to clinical and occupational assessment in the diagnosis of pneumoconioses, particularly in the context of rare disease entities. Med Pr Work Health Saf. 2026;77(1):81-88.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"81-88"},"PeriodicalIF":0.9,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Workplace safety behaviors in the context of selected employee and organizational factors: a latent profile analysis. 工作场所安全行为在选定的员工和组织因素的背景下:一个潜在的轮廓分析。
IF 0.9 Pub Date : 2025-12-18 Epub Date: 2025-11-12 DOI: 10.13075/mp.5893.01652
Łukasz Kapica, Andrzej Najmiec, Witold Sygocki

Background: This study aimed to identify distinct employee and organizational profiles influencing workplace safety behaviors (compliance and participation) using latent profile analysis (LPA), focusing on psychological need satisfaction, work performance, and organizational safety culture.

Material and methods: A cross-sectional survey of 1293 Polish employees across diverse sectors (industry, transportation, construction, agriculture) assessed individual factors (personal safety culture, basic psychological needs, task/contextual performance, counterproductive behaviors) and organizational factors (safety values, leadership commitment, training quality, psychosocial climate). Validated scales, including the Basic Psychological Need Satisfaction and Frustration Scale at Work, Individual Work Performance Questionnaire, individual safety culture questionnaire (Kultura bezpieczeństwa jednostki), and organizational safety culture questionnaire (Kultura bezpieczeństwa zakładu), were administered via computer-assisted web interview. Separate LPAs identified employee and organizational profiles; non-parametric tests compared safety outcomes across profiles.

Results: Five latent profiles emerged for both employees and organizations. Employees with high basic need satisfaction, strong personal safety values, and high performance exhibited the highest safety compliance and participation. Conversely, those with unmet needs despite strong safety values showed the lowest level of safety behaviors. Organizations with holistic safety cultures (leadership commitment, tailored training, psychosocial support) achieved superior safety outcomes, while those neglecting systemic safety investments performed the poorest.

Conclusions: Workplace safety behaviors are shaped by interactions between various individual and organizational variables. The study highlighted the importance of both organizational factors, such as safety climate, and individual factors, including need satisfaction, performance, and counterproductive behaviors. Med Pr Work Health Saf. 2025;76(6):435-447.

背景:本研究旨在利用潜在特征分析(LPA)找出影响工作场所安全行为(合规和参与)的不同员工和组织特征,重点关注心理需求满足、工作绩效和组织安全文化。材料和方法:对来自不同部门(工业、交通、建筑、农业)的1293名波兰员工进行了横断面调查,评估了个人因素(个人安全文化、基本心理需求、任务/情境表现、反生产行为)和组织因素(安全价值观、领导承诺、培训质量、社会心理气候)。本研究采用计算机辅助网络访谈的方法,对工作中基本心理需求满意度和挫败感量表、个人工作绩效问卷、个人安全文化问卷(Kultura bezpieczeństwa jednoski)和组织安全文化问卷(Kultura bezpieczeństwa zakładu)进行了验证。独立的lpa确定了员工和组织概况;非参数测试比较了不同剖面的安全结果。结果:在员工和组织中都出现了五种潜在的特征。基本需求满意度高、个人安全价值观强、工作绩效高的员工安全依从性和参与程度最高。相反,那些安全观较强但需求未得到满足的人,其安全行为水平最低。拥有整体安全文化(领导承诺、量身定制的培训、社会心理支持)的组织取得了卓越的安全成果,而那些忽视系统性安全投资的组织表现最差。结论:工作场所安全行为是由各种个体和组织变量之间的相互作用形成的。该研究强调了组织因素(如安全气候)和个人因素(包括需求满足、绩效和反生产行为)的重要性。医学Pr工作卫生安全,2025;76(6)。
{"title":"Workplace safety behaviors in the context of selected employee and organizational factors: a latent profile analysis.","authors":"Łukasz Kapica, Andrzej Najmiec, Witold Sygocki","doi":"10.13075/mp.5893.01652","DOIUrl":"10.13075/mp.5893.01652","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to identify distinct employee and organizational profiles influencing workplace safety behaviors (compliance and participation) using latent profile analysis (LPA), focusing on psychological need satisfaction, work performance, and organizational safety culture.</p><p><strong>Material and methods: </strong>A cross-sectional survey of 1293 Polish employees across diverse sectors (industry, transportation, construction, agriculture) assessed individual factors (personal safety culture, basic psychological needs, task/contextual performance, counterproductive behaviors) and organizational factors (safety values, leadership commitment, training quality, psychosocial climate). Validated scales, including the <i>Basic Psychological Need Satisfaction and Frustration Scale at Work</i>, <i>Individual Work Performance Questionnaire</i>, individual safety culture questionnaire (<i>Kultura bezpieczeństwa jednostki</i>), and organizational safety culture questionnaire (<i>Kultura bezpieczeństwa zakładu</i>), were administered via computer-assisted web interview. Separate LPAs identified employee and organizational profiles; non-parametric tests compared safety outcomes across profiles.</p><p><strong>Results: </strong>Five latent profiles emerged for both employees and organizations. Employees with high basic need satisfaction, strong personal safety values, and high performance exhibited the highest safety compliance and participation. Conversely, those with unmet needs despite strong safety values showed the lowest level of safety behaviors. Organizations with holistic safety cultures (leadership commitment, tailored training, psychosocial support) achieved superior safety outcomes, while those neglecting systemic safety investments performed the poorest.</p><p><strong>Conclusions: </strong>Workplace safety behaviors are shaped by interactions between various individual and organizational variables. The study highlighted the importance of both organizational factors, such as safety climate, and individual factors, including need satisfaction, performance, and counterproductive behaviors. Med Pr Work Health Saf. 2025;76(6):435-447.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"435-447"},"PeriodicalIF":0.9,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Potential hazards to medical personnel resulting from exposure to paclitaxel]. [接触紫杉醇对医务人员的潜在危害]。
IF 0.9 Pub Date : 2025-12-18 Epub Date: 2025-12-03 DOI: 10.13075/mp.5893.01660
Małgorzata Kupczewska-Dobecka, Joanna Jurewicz

This article, aimed at assessing potential health risks to medical personnel, presents a literature review on paclitaxel (PTX), a natural taxane alkaloid widely used in cancer chemotherapy. The review analyzes the toxic properties of PTX, occupational exposure routes and sources, as well as findings from environmental and biological monitoring studies and potential health effects. The methodology included a review of literature from reputable databases, institutional reports on hazardous medicinal products, and data from national registries. The results confirm that, despite its effectiveness in cancer treatment, PTX is a highly toxic substance associated with significant occupational risk. Due to its high molecular weight and relatively high vapor pressure, exposure may occur via inhalation and dermal contact during various stages of drug handling - from preparation to contact with patients' excreta. Biological monitoring has detected PTX in the urine and plasma of healthcare workers, while environmental monitoring has confirmed widespread surface contamination in medical facilities. The potential health effects of PTX primarily include mutagenic and genotoxic actions (aneugenicity, clastogenicity, DNA damage, chromosomal aberrations, and micronuclei formation), as well as neurotoxicity, myelosuppression, hepatotoxicity, and adverse effects on reproduction (embryotoxicity, fetotoxicity, and impaired fertility). To identify irregularities early and effectively reduce health risks associated with PTX exposure, a comprehensive occupational exposure assessment should become standard practice. This assessment should incorporate 3 complementary components: biological monitoring of workers, air concentration measurements, and surface contamination testing using wipe sampling. The inclusion of surface contamination measurements as a routine exposure surveillance method should be recognized as a best practice in healthcare settings where cytotoxic substances are used. A reference value of 0.1 ng/cm² for surface contamination is recommended. The implementation of effective preventive measures, appropriate personal protective equipment, regular decontamination, and staff training is essential for protecting the health of medical personnel. Med Pr Work Health Saf. 2025;76(6):469-486.

紫杉醇是一种广泛应用于肿瘤化疗的天然紫杉烷类生物碱,本文综述了紫杉醇(PTX)的相关文献,旨在评估其对医务人员的潜在健康风险。这篇综述分析了PTX的毒性、职业接触途径和来源,以及环境和生物监测研究的结果和潜在的健康影响。该方法包括审查来自知名数据库的文献、关于危险药品的机构报告以及来自国家登记处的数据。结果证实,尽管PTX在癌症治疗中有效,但它是一种与重大职业风险相关的剧毒物质。由于其高分子量和相对较高的蒸气压,在药物处理的各个阶段-从制备到与患者排泄物接触-可能通过吸入和皮肤接触发生暴露。生物监测已在医护人员的尿液和血浆中检测到PTX,而环境监测已证实医疗设施中广泛存在表面污染。PTX对健康的潜在影响主要包括诱变和遗传毒性作用(致畸性、致裂性、DNA损伤、染色体畸变和微核形成),以及神经毒性、骨髓抑制、肝毒性和对生殖的不利影响(胚胎毒性、胎儿毒性和生育力受损)。为了及早发现违规行为并有效减少与PTX接触有关的健康风险,应将全面的职业接触评估作为标准做法。该评估应包括3个互补部分:工作人员的生物监测、空气浓度测量和使用擦拭取样的表面污染测试。在使用细胞毒性物质的卫生保健环境中,应将表面污染测量纳入常规暴露监测方法,这是一种最佳做法。表面污染的参考值建议为0.1 ng/cm²。实施有效的预防措施、适当的个人防护装备、定期去污和对工作人员的培训对于保护医务人员的健康至关重要。医学Pr工作卫生安全,2025;76(6)。
{"title":"[Potential hazards to medical personnel resulting from exposure to paclitaxel].","authors":"Małgorzata Kupczewska-Dobecka, Joanna Jurewicz","doi":"10.13075/mp.5893.01660","DOIUrl":"10.13075/mp.5893.01660","url":null,"abstract":"<p><p>This article, aimed at assessing potential health risks to medical personnel, presents a literature review on paclitaxel (PTX), a natural taxane alkaloid widely used in cancer chemotherapy. The review analyzes the toxic properties of PTX, occupational exposure routes and sources, as well as findings from environmental and biological monitoring studies and potential health effects. The methodology included a review of literature from reputable databases, institutional reports on hazardous medicinal products, and data from national registries. The results confirm that, despite its effectiveness in cancer treatment, PTX is a highly toxic substance associated with significant occupational risk. Due to its high molecular weight and relatively high vapor pressure, exposure may occur via inhalation and dermal contact during various stages of drug handling - from preparation to contact with patients' excreta. Biological monitoring has detected PTX in the urine and plasma of healthcare workers, while environmental monitoring has confirmed widespread surface contamination in medical facilities. The potential health effects of PTX primarily include mutagenic and genotoxic actions (aneugenicity, clastogenicity, DNA damage, chromosomal aberrations, and micronuclei formation), as well as neurotoxicity, myelosuppression, hepatotoxicity, and adverse effects on reproduction (embryotoxicity, fetotoxicity, and impaired fertility). To identify irregularities early and effectively reduce health risks associated with PTX exposure, a comprehensive occupational exposure assessment should become standard practice. This assessment should incorporate 3 complementary components: biological monitoring of workers, air concentration measurements, and surface contamination testing using wipe sampling. The inclusion of surface contamination measurements as a routine exposure surveillance method should be recognized as a best practice in healthcare settings where cytotoxic substances are used. A reference value of 0.1 ng/cm² for surface contamination is recommended. The implementation of effective preventive measures, appropriate personal protective equipment, regular decontamination, and staff training is essential for protecting the health of medical personnel. Med Pr Work Health Saf. 2025;76(6):469-486.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"469-486"},"PeriodicalIF":0.9,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Occupational cancer in Poland - epidemiological analysis and challenges based on data from the Central Register of Occupational Diseases]. [波兰的职业癌症——基于职业病中央登记处数据的流行病学分析和挑战]。
IF 0.9 Pub Date : 2025-12-18 Epub Date: 2025-12-16 DOI: 10.13075/mp.5893.01670
Beata Świątkowska, Wojciech Hanke

Background: Malignant cancers are one of the most significant public health challenges, both in Poland and globally. In the context of increasing incidence, particular attention should be given to cancers with occupational etiology. Despite awareness of these risks, in Poland, this issue remains insufficiently recognized and registered within the occupational disease system. The aim of this study was to assess the occurrence occupational cancers in Poland 2015-2024, focusing on high-risk industries and the most common causes of occupational carcinogens.

Material and methods: The analysis included data on reported cases of confirmed occupational diseases 2015-2024, which were submitted by sanitary-epidemiological stations to the Central Register of Occupational Diseases at the Nofer Institute of Occupational Medicine in Łódź.

Results: In the analyzed period, 601 cases of occupational cancers were reported, including 512 in men and 89 in women. The most frequently diagnosed cancers were lung cancer (50.1%), pleural mesothelioma (36.6%), hematopoietic system cancers (3.3%), and laryngeal cancer (2.8%). The average duration of exposure was about 20 years. The highest number of cases was associated with industrial processing, mining, and construction, with dominant risk factors such as asbestos, benzene, and ionizing radiation. Asbestos exposure was responsible for all cases of pleural and peritoneal mesothelioma, >56% of lung cancers, and nearly 47% of laryngeal cancers.

Conclusions: The analysis revealed that occupational cancers account for only 2.7% of all reported occupational diseases indicating a significant underestimation. Further actions are needed to strengthen the detection, diagnosis, and prevention systems for these carcinogens. It is essential to introduce tools to monitor exposure to carcinogenic factors and to promote cooperation between employers, occupational health and safety services, doctors, and public health protection institutions. Med Pr Work Health Saf. 2025;76(6):449-456.

背景:恶性癌症是波兰和全球最重大的公共卫生挑战之一。在发病率不断上升的背景下,应特别注意职业性癌症。尽管认识到这些风险,但在波兰,这一问题在职业病系统中仍然没有得到充分认识和登记。本研究的目的是评估波兰2015-2024年职业癌症的发生情况,重点关注高风险行业和职业致癌物的最常见原因。材料和方法:分析2015-2024年卫生流行病学站向国立职业医学研究所职业病中央登记处(Łódź)提交的职业病确诊病例报告数据。结果:分析期内共报告职业性癌症601例,其中男性512例,女性89例。最常见的癌症是肺癌(50.1%)、胸膜间皮瘤(36.6%)、造血系统癌(3.3%)和喉癌(2.8%)。平均暴露时间约为20年。与工业加工、采矿和建筑相关的病例最多,主要危险因素如石棉、苯和电离辐射。石棉暴露导致了所有胸膜和腹膜间皮瘤病例,约56%的肺癌病例和近47%的喉癌病例。结论:分析显示,职业性癌症仅占所有报告职业病的2.7%,表明严重低估。需要进一步采取行动,加强对这些致癌物的检测、诊断和预防系统。必须采用各种工具来监测接触致癌因素的情况,并促进雇主、职业卫生和安全服务机构、医生和公共卫生保护机构之间的合作。医学Pr工作卫生安全,2025;76(6)。
{"title":"[Occupational cancer in Poland - epidemiological analysis and challenges based on data from the Central Register of Occupational Diseases].","authors":"Beata Świątkowska, Wojciech Hanke","doi":"10.13075/mp.5893.01670","DOIUrl":"10.13075/mp.5893.01670","url":null,"abstract":"<p><strong>Background: </strong>Malignant cancers are one of the most significant public health challenges, both in Poland and globally. In the context of increasing incidence, particular attention should be given to cancers with occupational etiology. Despite awareness of these risks, in Poland, this issue remains insufficiently recognized and registered within the occupational disease system. The aim of this study was to assess the occurrence occupational cancers in Poland 2015-2024, focusing on high-risk industries and the most common causes of occupational carcinogens.</p><p><strong>Material and methods: </strong>The analysis included data on reported cases of confirmed occupational diseases 2015-2024, which were submitted by sanitary-epidemiological stations to the Central Register of Occupational Diseases at the Nofer Institute of Occupational Medicine in Łódź.</p><p><strong>Results: </strong>In the analyzed period, 601 cases of occupational cancers were reported, including 512 in men and 89 in women. The most frequently diagnosed cancers were lung cancer (50.1%), pleural mesothelioma (36.6%), hematopoietic system cancers (3.3%), and laryngeal cancer (2.8%). The average duration of exposure was about 20 years. The highest number of cases was associated with industrial processing, mining, and construction, with dominant risk factors such as asbestos, benzene, and ionizing radiation. Asbestos exposure was responsible for all cases of pleural and peritoneal mesothelioma, >56% of lung cancers, and nearly 47% of laryngeal cancers.</p><p><strong>Conclusions: </strong>The analysis revealed that occupational cancers account for only 2.7% of all reported occupational diseases indicating a significant underestimation. Further actions are needed to strengthen the detection, diagnosis, and prevention systems for these carcinogens. It is essential to introduce tools to monitor exposure to carcinogenic factors and to promote cooperation between employers, occupational health and safety services, doctors, and public health protection institutions. Med Pr Work Health Saf. 2025;76(6):449-456.</p>","PeriodicalId":101460,"journal":{"name":"Medycyna pracy","volume":" ","pages":"449-456"},"PeriodicalIF":0.9,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Medycyna pracy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1