首页 > 最新文献

中华小儿外科杂志最新文献

英文 中文
Current status of surgery for osteogenesis imperfecta 成骨不全症的外科治疗现状
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.019
Yangyang Yao, Tianyou Li
Osteogenesis imperfecta (OI) is a congenital hereditary connective tissue disease caused by mesenchymal tissue hypoplasia and collagen formation disorder.Fragile bones often lead to repeated fractures along with long-bone deformities and scoliosis.The surgical objective is to fix fractures, correct long-bone deformities, boost the strength of fragile bones and treat scoliosis.Although some efficacies have been achieved, there is no uniform standard and controversies focus upon the timing and choice of surgical approaches.Through summarizing the relevant articles over the last two decades, this review discussed the development and current status of surgery for OI, summarized the achievements and controversies of surgery for long-bone deformity and scoliosis and introduced the implication of weight-loss surgery for OI. Key words: Osteogenesis imperfecta; Surgical procedures, operative; Weight-loss surgery
成骨不全症(Osteogenesis imperfecta, OI)是一种由间充质组织发育不全和胶原形成障碍引起的先天性遗传性结缔组织疾病。脆弱的骨骼经常导致反复骨折,并伴有长骨畸形和脊柱侧凸。手术的目的是固定骨折,矫正长骨畸形,增强脆弱骨骼的力量,治疗脊柱侧凸。虽然已经取得了一些疗效,但没有统一的标准,争议集中在手术入路的时机和选择上。本文通过对近二十年来相关文献的综述,讨论了成骨不全手术的发展和现状,总结了长骨畸形和脊柱侧凸手术的成就和争议,并介绍了减重手术治疗成骨不全的意义。关键词:成骨不全;外科手术;减肥手术
{"title":"Current status of surgery for osteogenesis imperfecta","authors":"Yangyang Yao, Tianyou Li","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.019","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.019","url":null,"abstract":"Osteogenesis imperfecta (OI) is a congenital hereditary connective tissue disease caused by mesenchymal tissue hypoplasia and collagen formation disorder.Fragile bones often lead to repeated fractures along with long-bone deformities and scoliosis.The surgical objective is to fix fractures, correct long-bone deformities, boost the strength of fragile bones and treat scoliosis.Although some efficacies have been achieved, there is no uniform standard and controversies focus upon the timing and choice of surgical approaches.Through summarizing the relevant articles over the last two decades, this review discussed the development and current status of surgery for OI, summarized the achievements and controversies of surgery for long-bone deformity and scoliosis and introduced the implication of weight-loss surgery for OI. \u0000 \u0000 \u0000Key words: \u0000Osteogenesis imperfecta; Surgical procedures, operative; Weight-loss surgery","PeriodicalId":10157,"journal":{"name":"中华小儿外科杂志","volume":"23 1","pages":"1052-1056"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85032483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One case of congenital laparoscopic choledochal cyst with postoperative chylousascites and a retrospective literature review 先天性腹腔镜胆总管囊肿合并术后乳糜腹水1例并回顾性文献复习
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.013
Chengchao Lyu, Sheng-lin Le, Jiangyu Zhang, Peng Li, Jingzi Xiao
Objective To report one case of congenital laparoscopic choledochal cyst with postoperative chylous ascites and review the relevant literatures of this disease for enhancing its clinician awareness. Methods One 14-day boy was hospitalized due to 4-month prenatal ultrasonic finding of hilar mass of liver with persistent jaundice.After admission, liver function examination showed that alanine aminotransferase 110 U/L, aspartate aminotransferase 180 U/L, total bilirubin 310.9 μmol/L and direct bilirubin 183.0 μmol/L.Preoperative ultrasonography, magnetic resonance cholangiopancreatography (MRCP) and intraoperative angiography revealed choledochal cyst.After preoperative examinations, laparoscopic choledochal cyst resection and Roux-Y hepaticojejunostomy were performed.The databases of PubMed, Medline, Springer Link, Cochrane Library, CNKD and Wanfang were searched for such keywords as chylous ascites, choledochal cyst and neonatal.Four cases of choledochal cyst complicated with chylous ascites were reported in both Chinese and English up until October 2018. Results Chylous ascites became resolved after 3-week conservative treatments of fasting, total parenteral nutrition and octreotide.During a 6-month follow-up period, he grew healthily without a relapse.Four cases of choledochal cyst complicated with postoperative chylous ascites were reviewed in the literature.All of them were treated conservatively.One child received only dietary treatment due to a low amount of celiac drainage (20 ml). The maximal celiac drainage was 350 ml and treatment duration lasted from 15 days to 4 weeks.All children recovered and were discharged. Conclusions Congenital laparoscopic choledochal cyst with postoperative chylous ascites is a rare disease.However, its prognosis is excellent if it is diagnosed timely and treated properly. Key words: Chylous ascites; Choledochal cyst; Infant, newborn
目的报告1例先天性腹腔镜胆总管囊肿合并术后乳糜腹水,复习相关文献,提高临床对该病的认识。方法1例14天男婴因产前4个月超声检查发现肝门肿物伴持续性黄疸而住院。入院后肝功能检查:丙氨酸转氨酶110 U/L,天冬氨酸转氨酶180 U/L,总胆红素310.9 μmol/L,直接胆红素183.0 μmol/L。术前超声、磁共振胆管造影及术中造影显示胆总管囊肿。术前检查后行腹腔镜胆总管囊肿切除术及Roux-Y肝空肠吻合术。检索PubMed、Medline、Springer Link、Cochrane Library、CNKD、万方等数据库,关键词为乳糜腹水、胆总管囊肿、新生儿。截至2018年10月,共报告4例胆总管囊肿合并乳糜腹水。结果经禁食、全肠外营养和奥曲肽保守治疗3周后,乳糜腹水完全消失。在6个月的随访期间,患者健康成长,无复发。本文回顾了4例胆总管囊肿合并术后乳糜腹水的病例。所有患者均接受保守治疗。一名儿童因乳糜泻量低(20毫升)而仅接受饮食治疗。最大腹腔引流量350 ml,治疗时间15天~ 4周。所有儿童均已康复出院。结论先天性腹腔镜胆总管囊肿术后并发乳糜腹水是一种罕见的疾病。然而,如果诊断及时,治疗得当,预后良好。关键词:乳糜腹水;胆总管的囊肿;婴儿,新生
{"title":"One case of congenital laparoscopic choledochal cyst with postoperative chylousascites and a retrospective literature review","authors":"Chengchao Lyu, Sheng-lin Le, Jiangyu Zhang, Peng Li, Jingzi Xiao","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.013","url":null,"abstract":"Objective \u0000To report one case of congenital laparoscopic choledochal cyst with postoperative chylous ascites and review the relevant literatures of this disease for enhancing its clinician awareness. \u0000 \u0000 \u0000Methods \u0000One 14-day boy was hospitalized due to 4-month prenatal ultrasonic finding of hilar mass of liver with persistent jaundice.After admission, liver function examination showed that alanine aminotransferase 110 U/L, aspartate aminotransferase 180 U/L, total bilirubin 310.9 μmol/L and direct bilirubin 183.0 μmol/L.Preoperative ultrasonography, magnetic resonance cholangiopancreatography (MRCP) and intraoperative angiography revealed choledochal cyst.After preoperative examinations, laparoscopic choledochal cyst resection and Roux-Y hepaticojejunostomy were performed.The databases of PubMed, Medline, Springer Link, Cochrane Library, CNKD and Wanfang were searched for such keywords as chylous ascites, choledochal cyst and neonatal.Four cases of choledochal cyst complicated with chylous ascites were reported in both Chinese and English up until October 2018. \u0000 \u0000 \u0000Results \u0000Chylous ascites became resolved after 3-week conservative treatments of fasting, total parenteral nutrition and octreotide.During a 6-month follow-up period, he grew healthily without a relapse.Four cases of choledochal cyst complicated with postoperative chylous ascites were reviewed in the literature.All of them were treated conservatively.One child received only dietary treatment due to a low amount of celiac drainage (20 ml). The maximal celiac drainage was 350 ml and treatment duration lasted from 15 days to 4 weeks.All children recovered and were discharged. \u0000 \u0000 \u0000Conclusions \u0000Congenital laparoscopic choledochal cyst with postoperative chylous ascites is a rare disease.However, its prognosis is excellent if it is diagnosed timely and treated properly. \u0000 \u0000 \u0000Key words: \u0000Chylous ascites; Choledochal cyst; Infant, newborn","PeriodicalId":10157,"journal":{"name":"中华小儿外科杂志","volume":"131 1","pages":"1020-1024"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90790558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 10-year summary of recurrent ventral curvature after hypospadias repair 尿道下裂修复后复发腹曲度的10年总结
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.006
L. Zeng, Yidong Huang, Xue Ma, Xue Li, Zhibo Zhang
Objective To explore the causes and managements of recurrent ventral curvature after hypospadias repair. Methods From January 2009 to January 2019, retrospective reviews were performed for 115 consecutive patients in health information system with recurrent ventral curvature after hypospadias repairing.Among them, 28 patients underwent hypospadias repair with a median age of 35 (30-99) months.The median penile bending angle was 45°(30°-80°). Beside recurrent ventral curvature, there were also urethral fistula (n=17), dehiscent urethral orifice (n=3), urethral stricture (n=1), urethral diverticulum (n=3) and urethral diverticulum, dehiscent urethral orifice & urethral fistula after Duckett urethroplasty (n=1). Among 87 patients undergoing hypospadias repair at other hospitals, the median age was 62 (46-168) months and the median penile bending angle 52°(45°-90°). Beside recurrent ventral curvature, other concurrent conditions included urethral fistula (n=13), dehiscent urethral orifice (n=3), urethral dehiscence (n=10), urethral stricture (n=19), urethral diverticulum (n=12), urethral fistula/stricture (n=15), urethral stricture/diverticulum (n=10), urethral fistula/diverticulum & dehiscent urethral orifice (n=3) and urethral fistula/diverticulum/stricture (n=2). Results All of them underwent redo hypospadias operations at our hospital.Among 28 patients from our hospital, recurrent ventral curvature was corrected by Nesbit dorsal tunica albuginea placation (n=18), transecting constructed neourethra (n=9) and transecting constructed neourethra & Nesbit dorsal tunica albuginea placation (n=1). Urethral complications were corrected simultaneously.The median follow-up period was 28 (6-60) months.There was no recurrent ventral curvature except for mild curvature (10°) in 1 child.Three cases of urethral fistula achieved satisfactory outcomes after re-operation.There was no urethral stricture/diverticulum.The urinary flow rate was examined at 6 months post-operation and the maximal urinary flow rate was 8.7 ml/s with an average of (5.4-16.5) ml/s.Among 87 patients from other hospitals, recurrent ventral curvature was corrected by degloved penis, releasing ventral fibrous tissue and removing ventral scar tissue(n=12). Recurrent ventral curvature were corrected by Nesbit dorsal tunica albuginea placation (n=18), transecting constructed neourethra (n=35), transecting constructed neourethra & Nesbit dorsal tunica albuginea placation (n=20) and transecting constructed neourethra & dorsal tunica albuginea patch by tunica vaginalis (n=2). Urethral complications were corrected simultaneously (n=84) while 3 patients required staged buccal mucosa graft urethroplasty because of no material available.The mean follow-up period was 37 (6-48) months.There was no onset of recurrent ventral curvature except for mild curvature (5°-10°) in 6 patients.Urethral fistula recurred in 12 children.Except for 1 case awaiting fistula repair, the remainder achieved sati
目的探讨尿道下裂修复术后腹曲度复发的原因及处理方法。方法对2009年1月至2019年1月在健康信息系统中连续就诊的115例尿道下裂修复术后复发腹曲度患者进行回顾性分析。其中28例患者行尿道下裂修复术,中位年龄为35(30-99)个月。中位阴茎弯曲角度为45°(30°~ 80°)。除腹侧弯复发外,还有尿道瘘(n=17)、尿道口开裂(n=3)、尿道狭窄(n=1)、尿道憩室(n=3)和尿道憩室、尿道口开裂、尿道瘘(n=1)。87例外院行尿道下裂修补术患者中位年龄为62(46 ~ 168)个月,中位阴茎弯曲角度为52°(45°~ 90°)。除复发性腹侧弯曲外,其他并发疾病包括尿道瘘(n=13)、尿道裂口(n=3)、尿道裂口(n=10)、尿道狭窄(n=19)、尿道憩室(n=12)、尿道瘘/狭窄(n=15)、尿道狭窄/憩室(n=10)、尿道瘘/憩室+尿道裂口(n=3)、尿道瘘/憩室/狭窄(n=2)。结果所有患者均在我院行尿道下裂手术。本院28例患者中,采用Nesbit背侧白膜置换术(n=18)、人工神经管道横断术(n=9)、人工神经管道横断- Nesbit背侧白膜置换术(n=1)矫正复发性腹曲。同时纠正尿道并发症。中位随访时间为28(6-60)个月。除1例患儿出现轻度腹侧弯曲(10°)外,无腹侧弯曲复发。3例尿道瘘患者再次手术治疗效果满意。无尿道狭窄/憩室。术后6个月检查尿流率,最大尿流率为8.7 ml/s,平均(5.4 ~ 16.5)ml/s。87例外院患者采用脱套阴茎、释放腹侧纤维组织、切除腹侧瘢痕组织的方法矫正复发性腹侧曲度(n=12)。采用Nesbit背侧白膜置换术(n=18)、横切人工神经(n=35)、横切人工神经与Nesbit背侧白膜置换术(n=20)、用阴道膜横切人工神经与背侧白膜贴片(n=2)矫正反复腹侧弯曲。同时纠正尿道并发症(n=84), 3例患者因无材料需分期行颊黏膜移植尿道成形术。平均随访37(6-48)个月。6例患者除轻度腹侧弯曲(5°-10°)外,未出现复发性腹侧弯曲。12例患儿尿道瘘复发。除1例等待修复外,其余患者再次手术后均取得满意效果。3例患者出现尿道狭窄,经尿道扩张3个月后效果满意。尿道口裂1例,尿道憩室裂2例。由于排尿正常,他们都不需要手术。术后6个月检查尿流率,最大尿流率8.3 ml/s,平均(4.9 ~ 15.8)ml/s。颊粘膜移植存活良好,两名儿童在分期尿道成形术后获得满意的结果,另一名儿童等待尿道成形术。结论针对不同类型的脊索,应优化矫正方案。并应普及尿道下裂知识,建立对尿道下裂患者的长期随访制度,尽量减少尿道下裂修复后腹曲度复发的发生率。关键词:尿道下裂;阴茎腹侧弯曲;术后并发症
{"title":"A 10-year summary of recurrent ventral curvature after hypospadias repair","authors":"L. Zeng, Yidong Huang, Xue Ma, Xue Li, Zhibo Zhang","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.006","url":null,"abstract":"Objective \u0000To explore the causes and managements of recurrent ventral curvature after hypospadias repair. \u0000 \u0000 \u0000Methods \u0000From January 2009 to January 2019, retrospective reviews were performed for 115 consecutive patients in health information system with recurrent ventral curvature after hypospadias repairing.Among them, 28 patients underwent hypospadias repair with a median age of 35 (30-99) months.The median penile bending angle was 45°(30°-80°). Beside recurrent ventral curvature, there were also urethral fistula (n=17), dehiscent urethral orifice (n=3), urethral stricture (n=1), urethral diverticulum (n=3) and urethral diverticulum, dehiscent urethral orifice & urethral fistula after Duckett urethroplasty (n=1). Among 87 patients undergoing hypospadias repair at other hospitals, the median age was 62 (46-168) months and the median penile bending angle 52°(45°-90°). Beside recurrent ventral curvature, other concurrent conditions included urethral fistula (n=13), dehiscent urethral orifice (n=3), urethral dehiscence (n=10), urethral stricture (n=19), urethral diverticulum (n=12), urethral fistula/stricture (n=15), urethral stricture/diverticulum (n=10), urethral fistula/diverticulum & dehiscent urethral orifice (n=3) and urethral fistula/diverticulum/stricture (n=2). \u0000 \u0000 \u0000Results \u0000All of them underwent redo hypospadias operations at our hospital.Among 28 patients from our hospital, recurrent ventral curvature was corrected by Nesbit dorsal tunica albuginea placation (n=18), transecting constructed neourethra (n=9) and transecting constructed neourethra & Nesbit dorsal tunica albuginea placation (n=1). Urethral complications were corrected simultaneously.The median follow-up period was 28 (6-60) months.There was no recurrent ventral curvature except for mild curvature (10°) in 1 child.Three cases of urethral fistula achieved satisfactory outcomes after re-operation.There was no urethral stricture/diverticulum.The urinary flow rate was examined at 6 months post-operation and the maximal urinary flow rate was 8.7 ml/s with an average of (5.4-16.5) ml/s.Among 87 patients from other hospitals, recurrent ventral curvature was corrected by degloved penis, releasing ventral fibrous tissue and removing ventral scar tissue(n=12). Recurrent ventral curvature were corrected by Nesbit dorsal tunica albuginea placation (n=18), transecting constructed neourethra (n=35), transecting constructed neourethra & Nesbit dorsal tunica albuginea placation (n=20) and transecting constructed neourethra & dorsal tunica albuginea patch by tunica vaginalis (n=2). Urethral complications were corrected simultaneously (n=84) while 3 patients required staged buccal mucosa graft urethroplasty because of no material available.The mean follow-up period was 37 (6-48) months.There was no onset of recurrent ventral curvature except for mild curvature (5°-10°) in 6 patients.Urethral fistula recurred in 12 children.Except for 1 case awaiting fistula repair, the remainder achieved sati","PeriodicalId":10157,"journal":{"name":"中华小儿外科杂志","volume":"9 1","pages":"981-987"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72660604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatments of pancreatic duct stones in children 儿童胰管结石的外科治疗
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.012
Lei Wu, Mingman Zhang, Ying-cun Li, Wanyi Zhou
Objective To explore the surgical approaches for pancreatic duct stones in children. Methods The clinical data were retrospectively analyzed for 8 surgical children with pancreatic duct stones from 2016 to 2017.There were 3 boys and 5 girls with a median age of 11.2 (8-13.8) years.All of them were clinically diagnosed by abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP). Results There was no case of mortality.No such early complications as pancreatic leakage, abdominal infection or anastomotic bleeding occurred.During an average follow-uPperiod of 18.12 (8-28) months, there was no manifestation of pancreatic internal/external secretion dysfunction such as diabetes and steatorrhea.Abdominal pain was completely relieved postoperatively.Three cases of occasional and no abdominal pain and 5 cases respectively.Postoperative stone residue and stone recurrence were 1 case and 1 cases respectively. Conclusions Large diameter pancreatic duct incision and Roux-en-Y pancreaticojejunostomy are efficacious for pancreatic duct stones in children. Key words: Child; Pancreatic duct stones; Pancreaticojejunostomy
目的探讨儿童胰管结石的手术治疗方法。方法回顾性分析2016 ~ 2017年8例手术患儿胰管结石的临床资料。男3例,女5例,中位年龄11.2(8 ~ 13.8)岁。经腹部计算机断层扫描(CT)和磁共振胰胆管造影(MRCP)进行临床诊断。结果本组无死亡病例。未发生胰漏、腹腔感染、吻合口出血等早期并发症。平均随访18.12(8-28)个月,未见糖尿病、脂肪漏等胰腺内外分泌功能障碍。术后腹痛完全缓解。偶有腹痛3例,无腹痛5例。术后结石残留1例,结石复发1例。结论大直径胰管切开联合Roux-en-Y胰空肠吻合术是治疗儿童胰管结石的有效方法。关键词:儿童;胰管结石;Pancreaticojejunostomy
{"title":"Surgical treatments of pancreatic duct stones in children","authors":"Lei Wu, Mingman Zhang, Ying-cun Li, Wanyi Zhou","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.012","url":null,"abstract":"Objective \u0000To explore the surgical approaches for pancreatic duct stones in children. \u0000 \u0000 \u0000Methods \u0000The clinical data were retrospectively analyzed for 8 surgical children with pancreatic duct stones from 2016 to 2017.There were 3 boys and 5 girls with a median age of 11.2 (8-13.8) years.All of them were clinically diagnosed by abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP). \u0000 \u0000 \u0000Results \u0000There was no case of mortality.No such early complications as pancreatic leakage, abdominal infection or anastomotic bleeding occurred.During an average follow-uPperiod of 18.12 (8-28) months, there was no manifestation of pancreatic internal/external secretion dysfunction such as diabetes and steatorrhea.Abdominal pain was completely relieved postoperatively.Three cases of occasional and no abdominal pain and 5 cases respectively.Postoperative stone residue and stone recurrence were 1 case and 1 cases respectively. \u0000 \u0000 \u0000Conclusions \u0000Large diameter pancreatic duct incision and Roux-en-Y pancreaticojejunostomy are efficacious for pancreatic duct stones in children. \u0000 \u0000 \u0000Key words: \u0000Child; Pancreatic duct stones; Pancreaticojejunostomy","PeriodicalId":10157,"journal":{"name":"中华小儿外科杂志","volume":"48 1","pages":"1015-1019"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85162809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical value of INSS/INRGSS staging of peripheral neuroblastictumors in children 儿童周围神经母细胞肿瘤INSS/INRGSS分期的临床价值
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.007
Chen Chenjun, D. Juan, Zhu Haobo, W. Lixia, Gu Yunfei
Objective To explore the role of International Neuroblastoma Staging System (INSS) or International Neuroblastoma Risk Group Staging System (INGRSS) in peripheral neuroblastic tumors. Methods From 2006 to 2018, a retrospective analysis was performed for 108 peripheral neuroblastictumors (pNT) children.There were 62 boys and 46 girls.All of them were operated and pathological examinations conducted.However, 4 s/Ms staged cases were excluded.Analyses were performed with regards to age, weight distribution, pathological results, INSS/INRGSS stage, neuron-specific enolase (NSE), lactate dehydrogenase (LDH), lesion size, image-defined risk factors (IDRFs), operative duration and tumor index.The relationship between stage and complete removal was explored. Results No statistically significant inter-gender difference existed in the distribution between tumors and the age of neuroblastoma (NB) was younger.The specific pathologies were NB (n=68), ganglioneuroblastoma (GNB, n=30) and ganglioneuroma (GN, n=10). No significant difference existed in the distribution of INSS/INRGSS staging.NSE and LDH values of pNTs with diameters >5 cm and L2 & M phases spiked sharply.The number of IDRFs was higher in NB than GNB.And pNT patients with diameters >10 cm, stages L2 & M and positive IDRFs had a longer operative duration and a lower probability of complete resection. Conclusions The preoperative evaluations of INSS/INRGSS staging for pNT offer more advantages than INSS staging alone.It may guide the choice of specific treatments.The presence or absence of IDRFs is an important factor for a complete removal of tumors. Key words: Neuroblastoma; Peripheral neuroblastictumors; Ganglioneuroblastoma; Ganglioneuroma
目的探讨国际神经母细胞瘤分期系统(INSS)或国际神经母细胞瘤危险分组分期系统(inggrss)在周围神经母细胞瘤中的作用。方法对2006年至2018年收治的108例儿童周围神经母细胞瘤(pNT)进行回顾性分析。有62名男孩和46名女孩。所有患者均行手术和病理检查。然而,4 s/Ms阶段的病例被排除在外。对年龄、体重分布、病理结果、INSS/INRGSS分期、神经元特异性烯醇化酶(NSE)、乳酸脱氢酶(LDH)、病变大小、图像定义危险因素(idrf)、手术时间和肿瘤指数进行分析。探讨了阶段与完全去除的关系。结果不同性别间肿瘤分布无统计学差异,神经母细胞瘤(NB)年龄越小。具体病理为NB (n=68)、神经节神经母细胞瘤(GNB, n=30)和神经节神经瘤(GN, n=10)。INSS/INRGSS分期分布差异无统计学意义。直径>5 cm的pnt和L2、M相的NSE和LDH值急剧上升。NB的idrf数量高于GNB。直径>10 cm、L2和M期及idrf阳性的pNT患者手术时间较长,完全切除的可能性较低。结论术前评价INSS/INRGSS分期比单独进行INSS分期更有优势。它可以指导具体治疗方法的选择。IDRFs的存在与否是肿瘤完全切除的重要因素。关键词:神经母细胞瘤;外围neuroblastictumors;Ganglioneuroblastoma;星形胶质细胞瘤
{"title":"Clinical value of INSS/INRGSS staging of peripheral neuroblastictumors in children","authors":"Chen Chenjun, D. Juan, Zhu Haobo, W. Lixia, Gu Yunfei","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.007","url":null,"abstract":"Objective \u0000To explore the role of International Neuroblastoma Staging System (INSS) or International Neuroblastoma Risk Group Staging System (INGRSS) in peripheral neuroblastic tumors. \u0000 \u0000 \u0000Methods \u0000From 2006 to 2018, a retrospective analysis was performed for 108 peripheral neuroblastictumors (pNT) children.There were 62 boys and 46 girls.All of them were operated and pathological examinations conducted.However, 4 s/Ms staged cases were excluded.Analyses were performed with regards to age, weight distribution, pathological results, INSS/INRGSS stage, neuron-specific enolase (NSE), lactate dehydrogenase (LDH), lesion size, image-defined risk factors (IDRFs), operative duration and tumor index.The relationship between stage and complete removal was explored. \u0000 \u0000 \u0000Results \u0000No statistically significant inter-gender difference existed in the distribution between tumors and the age of neuroblastoma (NB) was younger.The specific pathologies were NB (n=68), ganglioneuroblastoma (GNB, n=30) and ganglioneuroma (GN, n=10). No significant difference existed in the distribution of INSS/INRGSS staging.NSE and LDH values of pNTs with diameters >5 cm and L2 & M phases spiked sharply.The number of IDRFs was higher in NB than GNB.And pNT patients with diameters >10 cm, stages L2 & M and positive IDRFs had a longer operative duration and a lower probability of complete resection. \u0000 \u0000 \u0000Conclusions \u0000The preoperative evaluations of INSS/INRGSS staging for pNT offer more advantages than INSS staging alone.It may guide the choice of specific treatments.The presence or absence of IDRFs is an important factor for a complete removal of tumors. \u0000 \u0000 \u0000Key words: \u0000Neuroblastoma; Peripheral neuroblastictumors; Ganglioneuroblastoma; Ganglioneuroma","PeriodicalId":10157,"journal":{"name":"中华小儿外科杂志","volume":"30 1","pages":"988-992"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87444900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracoscopic repairing of anastomotic fistula with pedicled pleural flap after esophageal atresia surgery: one case report 胸腔镜带蒂胸膜瓣修复食管闭锁术后吻合口瘘1例报告
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.018
Bing Li, Wei-bing Chen, Shunlin Xia, Xiaomin Wang
{"title":"Thoracoscopic repairing of anastomotic fistula with pedicled pleural flap after esophageal atresia surgery: one case report","authors":"Bing Li, Wei-bing Chen, Shunlin Xia, Xiaomin Wang","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.018","url":null,"abstract":"","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"9 1","pages":"1050-1051"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73668722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of ultrasound in predicting the prognosis of congenital diaphragmatic hernia 超声对先天性膈疝预后的预测价值
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.009
Zhou Lin, Ye Wanding, Zheng Jinjue, Zhao Qifeng, Cheng Xianwei, Wu Daozhu
Objective To explore the value of ultrasonic scan for predicting mortality in children with congenital diaphragmatic hernia (CDH). Methods Sixty-eight hospitalized CDH neonates were recruited and retrospectively analyzed from January 2010 to May 2017.Ultrasonic markers including sidedness of hernia, thoracic herniation of liver, thoracic herniation of stomach, diagnostic timing, presence of associated congenital anomalies, lung-to-head ratio (LHR) and observed/expected lung-to-head ratio (O/E LHR) were analyzed.And logistic regression analysis was performed for determining the independent predictors for mortality. Results The overall mortality rate was 39.7%(27/68). Differences existed in mortality between children with an intrathoracic liver, associated congenital anomalies and prenatally diagnosed as compared with those with an ectopic liver without anomalies and diagnosed postnatally (P 0.05). The mortality of patients with LHR≤1.4 was 50% higher than that with LHR >1.4 (P 45% (P<0.05). The area under the ROC curve for predicting mortality by LHR was 0.936 (95% CI, 0.837-1.000) and O/E LHR 0.880 (95% CI, 0.745-1.000). The value of LHR and O/E LHR for predicting mortality was not significantly different (z=0.044, P=0.483). Logistic multivariate regression analysis indicated that prenatal diagnosis, thoracic herniation of liver and associated congenital anomalies were independent predictors for mortality with odd ratios of 10.534, 8.843 and 11.234 respectively (P<0.05). Conclusions Ultrasound may become a useful tool of predicting the prognosis of CDH. Key words: Diaphragmatic hernia, congenital; Ultrasonography; Prognosis
目的探讨超声扫描对先天性膈疝(CDH)患儿死亡率的预测价值。方法对2010年1月至2017年5月住院的68例CDH新生儿进行回顾性分析。分析超声指标包括疝气侧边度、胸段肝疝、胸段胃疝、诊断时机、是否存在相关先天性异常、肺头比(LHR)、观察/预期肺头比(O/E LHR)。并进行logistic回归分析以确定死亡率的独立预测因子。结果总死亡率为39.7%(27/68)。胸内肝、相关先天性异常和产前诊断的患儿与无异常和产后诊断的异位肝患儿的死亡率存在差异(p0.05)。LHR≤1.4的患者死亡率比LHR >1.4的患者高50% (P<0.05)。LHR预测死亡率的ROC曲线下面积为0.936 (95% CI, 0.837 ~ 1.000), O/E LHR为0.880 (95% CI, 0.745 ~ 1.000)。LHR和O/E LHR对死亡率的预测价值差异无统计学意义(z=0.044, P=0.483)。Logistic多因素回归分析显示,产前诊断、胸段肝疝及相关先天性异常是死亡率的独立预测因素,奇比分别为10.534、8.843、11.234 (P<0.05)。结论超声可作为预测CDH预后的有效工具。关键词:膈疝;先天性;超声;预后
{"title":"Value of ultrasound in predicting the prognosis of congenital diaphragmatic hernia","authors":"Zhou Lin, Ye Wanding, Zheng Jinjue, Zhao Qifeng, Cheng Xianwei, Wu Daozhu","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.009","url":null,"abstract":"Objective \u0000To explore the value of ultrasonic scan for predicting mortality in children with congenital diaphragmatic hernia (CDH). \u0000 \u0000 \u0000Methods \u0000Sixty-eight hospitalized CDH neonates were recruited and retrospectively analyzed from January 2010 to May 2017.Ultrasonic markers including sidedness of hernia, thoracic herniation of liver, thoracic herniation of stomach, diagnostic timing, presence of associated congenital anomalies, lung-to-head ratio (LHR) and observed/expected lung-to-head ratio (O/E LHR) were analyzed.And logistic regression analysis was performed for determining the independent predictors for mortality. \u0000 \u0000 \u0000Results \u0000The overall mortality rate was 39.7%(27/68). Differences existed in mortality between children with an intrathoracic liver, associated congenital anomalies and prenatally diagnosed as compared with those with an ectopic liver without anomalies and diagnosed postnatally (P 0.05). The mortality of patients with LHR≤1.4 was 50% higher than that with LHR >1.4 (P 45% (P<0.05). The area under the ROC curve for predicting mortality by LHR was 0.936 (95% CI, 0.837-1.000) and O/E LHR 0.880 (95% CI, 0.745-1.000). The value of LHR and O/E LHR for predicting mortality was not significantly different (z=0.044, P=0.483). Logistic multivariate regression analysis indicated that prenatal diagnosis, thoracic herniation of liver and associated congenital anomalies were independent predictors for mortality with odd ratios of 10.534, 8.843 and 11.234 respectively (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Ultrasound may become a useful tool of predicting the prognosis of CDH. \u0000 \u0000 \u0000Key words: \u0000Diaphragmatic hernia, congenital; Ultrasonography; Prognosis","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"192 1","pages":"998-1001"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82086429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overlooked complications after hypospadias repairing 尿道下裂修复术后被忽视的并发症
Q4 Medicine Pub Date : 2019-11-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.11.001
Liu Wei, Wu Rongde
{"title":"Overlooked complications after hypospadias repairing","authors":"Liu Wei, Wu Rongde","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.11.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.11.001","url":null,"abstract":"","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"62 1","pages":"961-962"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91350853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of associating liver partition and portal vein ligation for staged hepatectomy for infantile hepatic tumor: a case report 联合肝分区门静脉结扎在婴幼儿肝肿瘤分期切除中的应用1例
Q4 Medicine Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.10.016
Zhi-lin Xu, Wei Fan, Long Wang
{"title":"Application of associating liver partition and portal vein ligation for staged hepatectomy for infantile hepatic tumor: a case report","authors":"Zhi-lin Xu, Wei Fan, Long Wang","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.10.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.10.016","url":null,"abstract":"","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"13 1","pages":"944-946"},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75431673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One case report of pediatric primary mediastinal Ewing's sarcoma / primitive neuroectodermal tumor 小儿原发性纵隔尤文氏肉瘤/原始神经外胚层肿瘤1例报告
Q4 Medicine Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.10.017
Liping Wang, Pengbin Zhang, Xiaofeng Lu, Hong-tao Tang
{"title":"One case report of pediatric primary mediastinal Ewing's sarcoma / primitive neuroectodermal tumor","authors":"Liping Wang, Pengbin Zhang, Xiaofeng Lu, Hong-tao Tang","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.10.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.10.017","url":null,"abstract":"","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"799 1","pages":"947-949"},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77537338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
中华小儿外科杂志
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1