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Clinical diagnoses and treatments of congenital diaphragmatic hernia of neonates without a prenatal diagnosis 未经产前诊断的新生儿先天性膈疝的临床诊断与治疗
Q4 Medicine Pub Date : 2020-01-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2020.01.004
D. Pan, Wenya Xie, Zhongyuan Sun, X. Mu, Huifeng Liu, Min Yang, Xiaoyong Li, L. Shao
Objective To summarize the clinical characteristics, treatments and prognoses of congenital diaphagmatic hernia (CDH) in prenatal undiagnosed neonates and to explore the clinical diagnostic and therapeutic experiences of neonatal CDH at a non-tertiary center. Methods From January 2010 to December 2018, a total of 136 CDH neonates were admitted by emergency clinic. Five untreated cases due to special reasons were excluded. No prenatal diagnosis was made. There were 77 boys and 54 girls with a gestational age of (38.3±1.5)(32.0-41.0) weeks and a birth weight of (3102.8±473.6)(2000.0-4120.0) grams. The involved side was left (n=115) and right (n=16). The complications included pulmonary hypertension (n=21) and associated malformations (n=81). The preoperative status was mechanical ventilation (n=92) and spontaneous breathing (n=39). According to admission age, they were divided into two group of admission before and after 48 hours after birth. Results The specific procedures included thoracoscopy (n=58) and laparotomy (n=14). Death occurred preoperatively (n=2) and postoperatively (n=12). Two actively treated cases eventually died preoperatively and 129 cases were operated. Twelve cases died or abandoned treatment at post-operation and 117 cases (89.3%) survived. The mortality rate of ≤48 h admission group (14/90, 15.6%) was higher than that of >48 h admission group (0)(P<0.05). The mortality rate of premature infants, pulmonary hypertension and severe cardiac malformation were relatively high (P<0.05). And the values of pH and PaO2 at admission, mean postoperative pH in deceased cases were significantly lower than those in survivors. And PaCO2 at admission was significantly higher in deceased cases than that in survivors (P<0.05). Conclusions Prenatally undiagnosed neonatal CDH, especially in severe cases, may present challenges for postpartum treatment. With earlier onset and more severe condition, the higher mortality rate will be. Mortality is higher in CDH with pulmonary hypertension, preterm birth and severe cardiac malformation. Key words: Infant, newborn; Diaphragmatic hernia; Prenatal diagnosis; Therapy; Prognosis
目的总结产前未确诊新生儿先天性膈疝(CDH)的临床特点、治疗及预后,探讨非三级中心新生儿先天性膈疝的临床诊治经验。方法2010年1月至2018年12月,我院急诊收治136例CDH新生儿。排除5例因特殊原因未治疗的病例。没有产前诊断。男77例,女54例,胎龄(38.3±1.5)(32.0 ~ 41.0)周,出生体重(3102.8±473.6)(2000.0 ~ 420.0)g。受累侧分别为左侧(n=115)和右侧(n=16)。并发症包括肺动脉高压(21例)及相关畸形(81例)。术前状态为机械通气(n=92),自主呼吸(n=39)。根据入院年龄分为出生前48小时入院组和出生后48小时入院组。结果具体手术包括胸腔镜手术(58例)和剖腹手术(14例)。死亡发生在术前(n=2)和术后(n=12)。积极治疗2例术前死亡,手术129例。术后死亡或放弃治疗12例,存活117例(89.3%)。入院≤48 h组死亡率(14/90,15.6%)高于入院≤48 h组(0)(P<0.05)。早产儿、肺动脉高压、严重心脏畸形死亡率较高(P<0.05)。入院时pH值、PaO2值及术后平均pH值均明显低于存活患者。死亡患者入院时PaCO2明显高于存活患者(P<0.05)。结论产前未确诊的新生儿CDH,特别是严重病例,可能对产后治疗提出挑战。发病越早,病情越严重,死亡率越高。合并肺动脉高压、早产和严重心脏畸形的CDH死亡率较高。关键词:婴幼儿;新生儿;膈疝;产前诊断;治疗;预后
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引用次数: 0
The risk factors of failure of reduction in children with developmental dysplasia of the hip treated by closed reduction and cast immobilization 儿童发育性髋关节发育不良采用闭合复位和石膏固定治疗复位失败的危险因素
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.004
Zhe Yuan, Yiqiang Li, Min Ye, Yuanzhong Liu, Jingchun Li, F. Xun, Yanhan Liu
Objective To explore the risk factors of failed reduction after closed reduction in children with developmental dysplasia of the hip (DDH). Methods Retrospective reviews were conducted for the clinical and radiographic data of DDH children undergoing closed reduction and cast immobilization from July 2015 to November 2018. The relevant clinical data were collected, including age, gender, sideness, pavlic treatment pre-reduction, appearance of epiphyseal ossification center, International Hip Dysplasia Institute (IHDI) grade, acetabular index (AI), safe zoom, inverted limbus, medial pool distance of hip (MPD) and abduction angle of hip. The risk factors of failed reduction were evaluated by Logistic regression, t test and Chi-square test and fisher exact probability. Results Sixteen hips (9.2%) failed to achieve initial stable reduction and yet 7 hips (43.8%) obtained stable reduction through a second closed reduction and modified cast immobilization. Thus the modified rate of failed closed reduction was 5.2%(9/173). Single factor Logistic regression indicated that the failure of closed reduction was associated with gender, age, AI, inverted limbus and MPD. Multiple factor Logistic regression showed that MPD and AI are the risk factors. Receiver operating characteristic curve (ROC) showed MPD >6 mm were the risk factors of failure of closed reduction for DDH. The failure rate of closed reduction in children with indistinct limbus (83.3%, 5/6) and medial pool (36.8%, 7/19) on arthrography were significantly higher than those with distinct limbus (6.5%, 11/167) and medial pool (5.8%, 9/154) on arthrography (P<0.001). According to the outcome of closed reduction, they were divided into two groups of successful closed reduction (n=157) and failed closed reduction (n=16). The difference of AI of both groups (36.8°±4.5 and 34.4°±3.7° respectively) are statistically significant (P<0.05). Conclusions AI and MPD are the risk factors of failure closed reduction. Patients with MPD >6 mm during operation significantly increase the risk of failure of closed reduction for DDH.Unclearness of limbus and medial pool of hip during arthrography hint the failure of closed reduction for DDH. Key words: Hip joint; Close reduction; Risk factor; Developmental dysplasia of the hip
目的探讨儿童发育性髋关节发育不良(DDH)闭合复位失败的危险因素。方法回顾性分析2015年7月至2018年11月DDH患儿行闭合复位铸造固定的临床和影像学资料。收集患者的相关临床资料,包括年龄、性别、侧边度、骨盆治疗前复位、骨骺骨化中心外观、国际髋关节发育不良研究所(IHDI)分级、髋臼指数(AI)、安全变焦、髋缘倒置、髋关节内侧池距(MPD)、髋关节外展角。采用Logistic回归、t检验、卡方检验和fisher精确概率对降低失败的危险因素进行评价。结果16髋(9.2%)首次复位失败,7髋(43.8%)通过第二次闭合复位和改良石膏固定获得稳定复位。因此闭合复位失败修正率为5.2%(9/173)。单因素Logistic回归分析显示闭合复位失败与性别、年龄、人工智能、倒缘和MPD有关。多因素Logistic回归分析显示,MPD和AI是危险因素。受试者工作特征曲线(ROC)显示MPD >6 mm是DDH闭合复位失败的危险因素。关节边缘不清(83.3%,5/6)和内侧关节池(36.8%,7/19)的儿童闭合复位失败率明显高于关节边缘明显(6.5%,11/167)和内侧关节池(5.8%,9/154)的儿童(术中P6 mm),明显增加DDH闭合复位失败的风险。关节造影术中不清楚髋关节边缘和内侧池提示DDH闭合复位失败。关键词:髋关节;关闭减少;风险因素;髋关节发育不良
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引用次数: 0
Application of enhanced recovery after surgery concept of multi-disciplinary treatment medical treatment for congenital duodenal obstruction during perioperative period 多学科综合治疗理念在先天性十二指肠梗阻围手术期医学治疗中的应用
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.009
Ling Liu, Qiang Bai, Chao Li, Yuhui Jiang, Lingyu Zhou, Min Xi, Shudi Yang
Objective To explore the feasibility and clinical efficacy of enhanced recovery after surgery (ERAS) concept of multi-disciplinary treatment (MDT) medical mode in perioperative application of congenital duodenal obstruction. Methods From June 2015 to December 2017, retrospective analysis was performed for 60 cases with congenital duodenal obstruction. According to parental wishes, they were divided into research group (ERAS of MDT mode, n=30) and control group (traditional methods, n=30), which were compared in postoperative milk for initial open time, operative duration, postoperative parenteral nutrition using days, postoperative complications, length of time and hospitalization expenses, etc. Results Time of initial milk intake, days of using parenteral nutrition and hospital stay in ERAS group were shorter than those of control group [(56.45±6.18) vs. (140.40±1.00) hours, (7.35±1.46) vs. (17.25±3.59) days and (11.2±1.76) vs. (22.3±4.15) days. And the differences were statistically significant (P 0.05). During a follow-up period of 8-12 weeks, no incisional infection or adhesive intestinal obstruction occurred in ERAS group and there was only 1 case (3.3%) of adhesive intestinal obstruction in control group. Conclusions ERAS concept of MDT medical mode is both safe and effective for perioperative management of children with congenital duodenal obstruction. It offers the advantages of reducing pains, accelerating postoperative rehabilitation and shortening hospitalization time. Key words: Infant; Duodenal obstruction; Enhanced recovery after surgery
目的探讨术后增强恢复(ERAS)概念多学科治疗(MDT)医学模式在先天性十二指肠梗阻围手术期应用的可行性及临床疗效。方法对2015年6月至2017年12月收治的60例先天性十二指肠梗阻患者进行回顾性分析。根据家长意愿将患儿分为研究组(MDT模式ERAS, n=30)和对照组(传统方法,n=30),比较两组患儿术后开乳时间、手术时间、术后肠外营养使用天数、术后并发症、时间长短、住院费用等情况。结果ERAS组患儿初乳时间、肠外营养使用天数、住院时间均短于对照组[(56.45±6.18)∶(140.40±1.00)小时,(7.35±1.46)∶(17.25±3.59)天,(11.2±1.76)∶(22.3±4.15)天]。差异有统计学意义(p0.05)。随访8 ~ 12周,ERAS组未发生切口感染和粘连性肠梗阻,对照组仅发生粘连性肠梗阻1例(3.3%)。结论ERAS概念的MDT医疗模式对儿童先天性十二指肠梗阻围手术期治疗安全有效。具有减轻疼痛、加快术后康复、缩短住院时间等优点。关键词:婴幼儿;十二指肠梗阻;增强术后恢复
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引用次数: 2
Dega osteotomy assisted with three-dimensional computed tomography for re-dislocation of developmental dysplasia of the hip in children Dega截骨术辅助三维计算机断层扫描治疗儿童发育性髋关节发育不良再脱位
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.003
Shuai Liu, Min-gang Zhang, Tianyou Li
Objective To observe the pathological changes of re-dislocation of developmental dysplasia of the hip (DDH) undergoing pelvic osteotomy in children, to predict the outcome of Dega osteotomy assisted with three-dimensional computed tomography (3DCT) simulating osteotomy and to explore the individual therapeutics for re-dislocation of DDH. Methods From July 2012 to June 2017, retrospective analysis was conducted for a total of 28 hips in 27 children with re-dislocated DDH undergoing a second Dega osteotomy. There were 9 involved hips in 8 boys and 19 involved hips in 19 girls with an average age of 51 (28-96) months during the second operation. The involved side was left (n=17), right (n=9) and bilateral (n=1). According to the Tonnis classification scheme, the clinical types were Ⅱ (17 hips), Ⅲ (8 hips) and Ⅳ (3 hips). And the procedures included Salter osteotomy (20 hips), Dega osteotomy (1 hip), Dega osteotomy with intact inner wall (3 hips) and Pemberton osteotomy (4 hips). A simulating osteotomy by 3DCT of pelvis-femurs was performed preoperatively and Dega osteotomy with open reduction plus capsuloplasty and proximal femoral osteotomy were applied simultaneously. The preoperative and postoperative changes of acetabular index and Reimer's index were compared and P<0.01 was deemed as statistically significant. Radiological findings and improvements of extremity functions were evaluated at the latest follow-up. Results 28 involved hips were followed up successfully with an average period of 33(18-38) months. Acetabular index improved from (31°±8°) to (11°±4°) and Reimer's index decreased (0.78±0.21) to (0.16±0.03) with statistically significant differences in both acetabular and Reimer's indices pre-reoperation and at the latest follow-up (P<0.01). Disrupted preoperative Shenton lines in all hips became continuous during follow-ups. No postoperative re-dislocation was seen. Based upon the modified Severin classification scheme, the outcomes were excellent (19 hips), good (7 hips) and moderate (2 hips). And the excellent-good rate was 93%(26/28); based upon the modified McKay classification scheme, the outcomes were excellent (20 hips), good (7 hips) and moderate (1 hip). And the excellent-good rate was 96%(27/28). There was no occurrence of infection, fracture or vascular/nervous injury. Conclusions With more precise designs, meticulous operations and intuitive outcomes may be achieved with an aid of 3DCT. The short-term effect of Dega osteotomy plus open reduction, capsuloplasty and proximal femoral osteotomy for re-dislocated of DDH undergoing pelvic osteotomyis is definite. And it should be further popularized clinically in children. Key words: Osteotomy; Three-Dimensional; Developmental dysplasia of the hip
目的观察儿童盆腔截骨术后发育性髋关节发育不良(DDH)再脱位的病理变化,预测Dega截骨辅助三维计算机断层扫描(3DCT)模拟截骨术的预后,探讨DDH再脱位的个体化治疗方法。方法回顾性分析2012年7月至2017年6月27例DDH再脱位患儿共28髋行第二次Dega截骨术。第二次手术时,8名男孩9髋受累,19名女孩19髋受累,平均年龄51(28-96)个月。受累侧为左侧(n=17)、右侧(n=9)和双侧(n=1)。根据Tonnis分型方案,临床分型分别为Ⅱ(17髋)、Ⅲ(8髋)和Ⅳ(3髋)。手术包括Salter截骨术(20髋)、Dega截骨术(1髋)、Dega截骨术(3髋)和Pemberton截骨术(4髋)。术前行骨盆-股骨3DCT模拟截骨术,同时行Dega切开复位加囊腔成形术及股骨近端截骨术。髋臼指数、Reimer’s指数术前、术后变化比较,P<0.01有统计学意义。在最近的随访中评估放射学表现和四肢功能的改善。结果28例受累髋成功随访,平均随访时间33(18-38)个月。髋臼指数由(31°±8°)改善至(11°±4°),Reimer指数由(0.78±0.21)降至(0.16±0.03),再手术前与最新随访时髋臼指数与Reimer指数差异均有统计学意义(P<0.01)。术前中断的所有髋关节的申顿线在随访期间变为连续。术后未见再脱位。根据改进的Severin分类方案,结果为优(19髋)、良(7髋)和中(2髋)。优良率为93%(26/28);根据改进的McKay分类方案,结果为优(20髋)、良(7髋)和中(1髋)。优良率为96%(27/28)。未发生感染、骨折或血管/神经损伤。结论在3DCT的辅助下,设计更精确,操作更细致,结果更直观。Dega截骨联合切开复位、囊成形术和股骨近端截骨术治疗盆腔截骨术后DDH再脱位的短期效果是明确的。在儿童临床中应进一步推广。关键词:截骨术;三维;髋关节发育不良
{"title":"Dega osteotomy assisted with three-dimensional computed tomography for re-dislocation of developmental dysplasia of the hip in children","authors":"Shuai Liu, Min-gang Zhang, Tianyou Li","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.12.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.12.003","url":null,"abstract":"Objective \u0000To observe the pathological changes of re-dislocation of developmental dysplasia of the hip (DDH) undergoing pelvic osteotomy in children, to predict the outcome of Dega osteotomy assisted with three-dimensional computed tomography (3DCT) simulating osteotomy and to explore the individual therapeutics for re-dislocation of DDH. \u0000 \u0000 \u0000Methods \u0000From July 2012 to June 2017, retrospective analysis was conducted for a total of 28 hips in 27 children with re-dislocated DDH undergoing a second Dega osteotomy. There were 9 involved hips in 8 boys and 19 involved hips in 19 girls with an average age of 51 (28-96) months during the second operation. The involved side was left (n=17), right (n=9) and bilateral (n=1). According to the Tonnis classification scheme, the clinical types were Ⅱ (17 hips), Ⅲ (8 hips) and Ⅳ (3 hips). And the procedures included Salter osteotomy (20 hips), Dega osteotomy (1 hip), Dega osteotomy with intact inner wall (3 hips) and Pemberton osteotomy (4 hips). A simulating osteotomy by 3DCT of pelvis-femurs was performed preoperatively and Dega osteotomy with open reduction plus capsuloplasty and proximal femoral osteotomy were applied simultaneously. The preoperative and postoperative changes of acetabular index and Reimer's index were compared and P<0.01 was deemed as statistically significant. Radiological findings and improvements of extremity functions were evaluated at the latest follow-up. \u0000 \u0000 \u0000Results \u000028 involved hips were followed up successfully with an average period of 33(18-38) months. Acetabular index improved from (31°±8°) to (11°±4°) and Reimer's index decreased (0.78±0.21) to (0.16±0.03) with statistically significant differences in both acetabular and Reimer's indices pre-reoperation and at the latest follow-up (P<0.01). Disrupted preoperative Shenton lines in all hips became continuous during follow-ups. No postoperative re-dislocation was seen. Based upon the modified Severin classification scheme, the outcomes were excellent (19 hips), good (7 hips) and moderate (2 hips). And the excellent-good rate was 93%(26/28); based upon the modified McKay classification scheme, the outcomes were excellent (20 hips), good (7 hips) and moderate (1 hip). And the excellent-good rate was 96%(27/28). There was no occurrence of infection, fracture or vascular/nervous injury. \u0000 \u0000 \u0000Conclusions \u0000With more precise designs, meticulous operations and intuitive outcomes may be achieved with an aid of 3DCT. The short-term effect of Dega osteotomy plus open reduction, capsuloplasty and proximal femoral osteotomy for re-dislocated of DDH undergoing pelvic osteotomyis is definite. And it should be further popularized clinically in children. \u0000 \u0000 \u0000Key words: \u0000Osteotomy; Three-Dimensional; Developmental dysplasia of the hip","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"107 1","pages":"1071-1076"},"PeriodicalIF":0.0,"publicationDate":"2019-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91192609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three cases of polyrchidism 多子体畸形3例
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.015
Ningning Yang, Qian Zhang, Ji Li, Lei Wang, Meng Su
{"title":"Three cases of polyrchidism","authors":"Ningning Yang, Qian Zhang, Ji Li, Lei Wang, Meng Su","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.12.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.12.015","url":null,"abstract":"","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"4 1","pages":"1134-1136"},"PeriodicalIF":0.0,"publicationDate":"2019-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89368168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arthroscopic treatment for aged anterior tibial spine fracture with absorbable suture fixation in children 关节镜下儿童可吸收缝线固定治疗老年胫骨前棘骨折
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.013
Xiaoliang Chen, Zhi-guo Zhou, Xiong-tao Li, Ji Wu, Ping Zhang
Objective To explore the efficacies of arthroscopic treatment for aged anterior tibial spine fracture with polydioxanone (PDS-II) suture fixation in children and to provide an effective, safe, reliable and mini-invasive treatment for old anterior tibial spine fracture. Methods Retrospective analysis was performed for 7 children with old tibial intercondylar spine fracture from January 2014 to January 2017. There were 5 boys and 2 girls. According to the Meyers & McKeever classification scheme, the fractures were divided into type Ⅱ (n=3) and type Ⅲ (n=4). All of them underwent arthroscopic reduction and PDS-Ⅱ absorbable suture for fixation. Gypsum was removed at 4 weeks postoperatively and functional exercises began. Weight was partially loaded at 6 weeks post-operation and completely loaded at 12 weeks postoperatively. Lysholm knee score was employed for evaluating knee functions before operation and at the last follow-up. At the last follow-up, standing plain films of both lower extremities were taken for recording the length of both lower extremities and the presence of varus deformity of knee joint. Results The average follow-up period was 15.3(12-18) months. All of them achieved primary healing within 3 months. The average motion range of knee joints normalized at 3 months postoperatively. There was no limitation of knee extension/flexion, pain or swelling of knee joint. Both anterior drawer and Lachman tests were negative. The average Lysholm score at the last follow-up was (93.8±3.1) as compared with the preoperative Lysholm score of (42.7±2.7). And the difference was statistically significant (t=63.96, P<0.01). Conclusions Arthroscopic fixation with absorbable suture is both safe and effective for old tibial intercondylar spine fracture in children. As a mini-invasive procedure, its curative effect is satisfactory and wider popularization is recommended. Key words: Arthroscopy; Tibial spine fracture; Old fracture
目的探讨关节镜下聚二氧环酮(PDS-II)缝合固定治疗儿童老年胫骨前棘骨折的疗效,为老年胫骨前棘骨折提供一种有效、安全、可靠的微创治疗方法。方法回顾性分析2014年1月至2017年1月收治的7例老年性胫骨髁间骨折患儿的临床资料。有5个男孩和2个女孩。根据Meyers & McKeever分类方案,将骨折分为Ⅱ型(n=3)和Ⅲ型(n=4)。所有患者均行关节镜复位和PDS-Ⅱ可吸收缝线固定。术后4周取出石膏,开始功能锻炼。术后6周部分负重,12周完全负重。术前及末次随访时采用Lysholm膝关节评分评价膝关节功能。最后随访时,拍摄双下肢站立平片,记录双下肢长度及膝关节内翻畸形情况。结果平均随访时间15.3(12 ~ 18)个月。所有患者均在3个月内获得初步愈合。术后3个月膝关节平均活动范围恢复正常。没有限制膝关节的伸展/屈曲,膝关节疼痛或肿胀。前抽屉试验和拉赫曼试验均呈阴性。末次随访时平均Lysholm评分为(93.8±3.1)分,术前Lysholm评分为(42.7±2.7)分。差异有统计学意义(t=63.96, P<0.01)。结论关节镜下可吸收缝线固定治疗儿童老年性胫骨髁间骨折安全有效。作为一种微创手术,其疗效满意,值得广泛推广。关键词:关节镜;胫骨骨折;老骨折
{"title":"Arthroscopic treatment for aged anterior tibial spine fracture with absorbable suture fixation in children","authors":"Xiaoliang Chen, Zhi-guo Zhou, Xiong-tao Li, Ji Wu, Ping Zhang","doi":"10.3760/CMA.J.ISSN.0253-3006.2019.12.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0253-3006.2019.12.013","url":null,"abstract":"Objective \u0000To explore the efficacies of arthroscopic treatment for aged anterior tibial spine fracture with polydioxanone (PDS-II) suture fixation in children and to provide an effective, safe, reliable and mini-invasive treatment for old anterior tibial spine fracture. \u0000 \u0000 \u0000Methods \u0000Retrospective analysis was performed for 7 children with old tibial intercondylar spine fracture from January 2014 to January 2017. There were 5 boys and 2 girls. According to the Meyers & McKeever classification scheme, the fractures were divided into type Ⅱ (n=3) and type Ⅲ (n=4). All of them underwent arthroscopic reduction and PDS-Ⅱ absorbable suture for fixation. Gypsum was removed at 4 weeks postoperatively and functional exercises began. Weight was partially loaded at 6 weeks post-operation and completely loaded at 12 weeks postoperatively. Lysholm knee score was employed for evaluating knee functions before operation and at the last follow-up. At the last follow-up, standing plain films of both lower extremities were taken for recording the length of both lower extremities and the presence of varus deformity of knee joint. \u0000 \u0000 \u0000Results \u0000The average follow-up period was 15.3(12-18) months. All of them achieved primary healing within 3 months. The average motion range of knee joints normalized at 3 months postoperatively. There was no limitation of knee extension/flexion, pain or swelling of knee joint. Both anterior drawer and Lachman tests were negative. The average Lysholm score at the last follow-up was (93.8±3.1) as compared with the preoperative Lysholm score of (42.7±2.7). And the difference was statistically significant (t=63.96, P<0.01). \u0000 \u0000 \u0000Conclusions \u0000Arthroscopic fixation with absorbable suture is both safe and effective for old tibial intercondylar spine fracture in children. As a mini-invasive procedure, its curative effect is satisfactory and wider popularization is recommended. \u0000 \u0000 \u0000Key words: \u0000Arthroscopy; Tibial spine fracture; Old fracture","PeriodicalId":10157,"journal":{"name":"Chinese Journal of Pediatric Surgery","volume":"30 1","pages":"1128-1131"},"PeriodicalIF":0.0,"publicationDate":"2019-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89952630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between intrahepatic bile duct development and hepatic fibrosis in children with biliary dysplasia 胆道发育不良患儿肝内胆管发育与肝纤维化的关系
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.008
Xin Li, Chen Yu, Wei Gao, Xiao-li Hu, J. Zhan
Objective To explore the pathological changes of intrahepatic bile duct development and liver fibrosis in children with biliary dysplasia at different ages and to explore the effect of intrahepatic bile duct development on liver fibrosis. Methods From January 2015 to January 2019, a total of 16 hospitalized children with biliary dysplasia at Municipal Children's Hospital and First Central Municipal Hospital were recruited and divided into two groups according to age, i. e. <180 days (G1, n=8) and ≥180 days (G2, n=8). Liver biopsy specimens were harvested intraoperatively for routine hematoxylin & eosin and immunohistochemical staining (CK19 & EMA). The major histopathological changes of liver, such as ratio of interlobular bile duct to portal area, diameter of interlobular bile duct, ductal proliferation, liver fibrosis, cholestasis, bile plugs in ductules and an infiltration of inflammatory cells in portal region, were analyzed. Results The pathological changes of G1 and G2 groups showed that the degree of liver fibrosis in G2 group was higher than that in G1 group [0.5(0, 1) vs. 4(2.25, 4)]. The inter-group difference was statistically significant (Z=3.467, P<0.001); The ratio of interlobular bile duct to portal area was lower in G2 group than that in G1 group [0.25(0.16, 0.34) vs. 0]. The inter-group difference was statistically significant (Z=2.663, P<0.05); The degree of ductal proliferation showed that G2 group was significantly higher than G1 group [1(0.25, 2) vs. 2.5(2, 3.75)]. The inter-group difference was statistically significant (Z=2.867, P<0.05). The expression of EMA was significantly lower in G2 group than that in G1 group [(0.034±0.012) vs. (0.082±0.009)]. The inter-group difference was statistically significant (t=9.432, P<0.001); The expression of CK19 was significantly higher in G2 group than that in G1 group [(0.201±0.016) vs. (0.135±0.010)]. There was significant inter-group difference (t=9.615, P<0.001). Correlation analysis of intrahepatic bile duct development revealed: ratio of interlobular bile duct to portal area and age of children (rs=-0.714, P=0.002), ductal proliferation (rs=-0.610, P=0.012) and liver fibrosis (rs=-0.533, P<0.05) showed a significant negative correlation. Conclusions With the aging of the patients, interlobular bile duct of children with biliary dysplasia decreases gradually. And the degree of hepatic fibrosis continues aggravating with a poor prognosis. Key words: Hepatic fibrosis; Interlobular bile duct; Deficiency symptom; Bile duct; Hyperplasia
目的探讨不同年龄胆道发育不良患儿肝内胆管发育及肝纤维化的病理变化,探讨肝内胆管发育对肝纤维化的影响。方法选取2015年1月~ 2019年1月在市儿童医院和市第一中心医院住院的胆道发育不良患儿16例,按年龄分为<180天组(G1, n=8)和≥180天组(G2, n=8)。术中取肝活检标本进行常规苏木精和伊红染色及免疫组织化学染色(CK19和EMA)。分析肝脏的主要组织病理学改变,如小叶间胆管与门静脉区比值、小叶间胆管直径、胆管增生、肝纤维化、胆汁淤积、胆管内胆塞及门静脉区炎症细胞浸润。结果G1组和G2组病理变化显示,G2组肝纤维化程度高于G1组[0.5(0,1)比4(2.25,4)]。组间差异有统计学意义(Z=3.467, P<0.001);G2组小叶间胆管与门静脉面积之比低于G1组[0.25(0.16,0.34)比0]。组间差异有统计学意义(Z=2.663, P<0.05);导管增生程度G2组明显高于G1组[1(0.25,2)vs. 2.5(2,3.75)]。组间差异有统计学意义(Z=2.867, P<0.05)。G2组EMA表达明显低于G1组[(0.034±0.012)∶(0.082±0.009)]。组间差异有统计学意义(t=9.432, P<0.001);CK19在G2组的表达明显高于G1组[(0.201±0.016)比(0.135±0.010)]。组间差异有统计学意义(t=9.615, P<0.001)。肝内胆管发育相关分析显示:小叶间胆管与门静脉面积之比与儿童年龄(rs=-0.714, P=0.002)、胆管增生(rs=-0.610, P=0.012)、肝纤维化(rs=-0.533, P<0.05)呈显著负相关。结论随着患者年龄的增长,胆道发育不良患儿小叶间胆管逐渐减少。肝纤维化程度继续加重,预后不良。关键词:肝纤维化;小叶间胆管;缺乏症状;胆管;增生
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引用次数: 1
Large twisted ovarian fibroma in a 4-year-old girl: One case report 4岁女童大卵巢扭曲纤维瘤1例报告
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.014
Ting Li
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引用次数: 0
Size of femoral head and its impact on the incidence of avascular necrosis in patients with developmental dysplasia of the hip after closed reduction 股骨头大小及其对闭合复位后发育不良髋关节患者缺血性坏死发生率的影响
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.006
JianPing Wu, Yiqiang Li, Jingchun Li, Zhe Yuan, F. Xun, Yanhan Liu, Yuanzhong Liu
Objective To explore the size of femoral head and its influencing factors in children with developmental dysplasia of the hip (DDH) and to examine the effect of size of femoral head and ossific nucleus on the development of avascular necrosis of femoral head (AVN) after closed reduction (CR). Methods Retrospective reviews were conducted for a consecutive series of DDH children undergoing CR. A total of 124 hips (111 children; mean age: 15.6±3.6 months) were included. The diameter (including anteroposterior, transverse & axial) and height of femoral head and ossific nucleus were assessed by magnetic resonance imaging (MRI) on coronal plane. And AVN was evaluated by the criteria of Kalamchi-MacEwen. Results The anteroposterior diameter of femoral head (1.91±0.27) cm, transverse diameter of femoral head (1.82±0.26) cm, height of femoral head (1.08±0.18) cm, anteroposterior of ossific nucleus (0.59±0.35) cm, transverse of ossific nucleus (0.49±0.28) cm, height of ossific nucleus (0.36±0.20) cm at contralateral side including 124 hips were significantly less developed than those at dislocated side including 98 hips (2.21±0.30), (2.27±0.19), (1.33±0.16), (1.06±0.33), (1.01±0.28) and (0.68±0.18) cm (P<0.001). AVN occurred in 21/124 hips (16.9%). According to the age, we divided the children into three groups. Group A: 6 ~ 12 months (20 hips), Group B: 13 ~ 18 months (77 hips), Group C: 19 ~ 24 months (27 hips). The rate of AVN was 30.0% (6/20) at group A, 18.2% (14/77) at group B and 3.7% (1/27) at group C. And the rate of AVN between the three groups was statistically different (χ2=6.800, P=0.033). For hip with AVN after closed reduction, anteroposterior diameter of femoral head (1.79±0.24) cm, transverse diameter of femoral head (1.69±0.19) cm and the anteroposterior diameter of ossific nudes(0.44±0.33)cm were less developed than those without AVN (1.98±0.27) cm, (1.89±0.28) cm and (0.62±0.36)cm (P<0.05). Spearman's correlation analysis showed that diameter of femoral head, diameter/height of ossific nucleus significantly increased with age but not height of femoral head; age was negatively correlated with the incidence of AVN (r=-0.274, P=0.002). The diameter of femoral head has significantly negative association with AVN grade (P<0.005). No significant association was observed between AVN grade and height of femoral head, presence of ossific nucleus, diameter/height of ossific nucleus and ratio of ossific nucleus to femoral head. Conclusions The size of femoral head at dislocated side is significantly worse than at contralateral side. And diameter of femoral head and diameter/height of ossific nucleus increase with advancing age. A significantly negative association exists between rate of AVN and diameter of femoral head. And it is unrelated with height of femoral head or size of ossific nucleus. Key words: Femoral head; Hip Joint; Closed reduction; Avascular necrosis of femoral head
目的探讨发育性髋关节发育不良(DDH)患儿股骨头大小及其影响因素,探讨股骨头大小及骨化核对股骨头缺血性坏死(AVN)闭合复位术(CR)发生的影响。方法对连续接受CR的DDH儿童进行回顾性分析,共124髋(111例儿童;平均年龄:15.6±3.6个月)。采用冠状面磁共振成像(MRI)测量股骨头和骨核的直径(包括正、横、轴)和高度。采用Kalamchi-MacEwen标准评价AVN。结果对侧124只髋关节脱位后股骨头前后径(1.91±0.27)cm、股骨头横径(1.82±0.26)cm、股骨头高度(1.08±0.18)cm、骨核前后径(0.59±0.35)cm、骨核横径(0.49±0.28)cm、骨核高度(0.36±0.20)cm发育明显低于对侧98只髋关节脱位后股骨头(2.21±0.30)、(2.27±0.19)、(1.33±0.16)、(1.06±0.33);(1.01±0.28)cm和(0.68±0.18)cm (P<0.001)。AVN发生在21/124髋(16.9%)。根据年龄,我们把孩子们分成三组。A组:6 ~ 12个月(20髋),B组:13 ~ 18个月(77髋),C组:19 ~ 24个月(27髋)。A组AVN发生率为30.0% (6/20),B组为18.2% (14/77),c组为3.7%(1/27),三组间AVN发生率差异有统计学意义(χ2=6.800, P=0.033)。闭式复位后,股骨头前径(1.79±0.24)cm、股骨头横径(1.69±0.19)cm、骨骺前径(0.44±0.33)cm发育较无AVN者(1.98±0.27)cm、(1.89±0.28)cm、(0.62±0.36)cm发育较差(P<0.05)。Spearman相关分析显示,股骨头直径、骨核直径/高度随年龄的增长而显著增加,股骨头高度不显著增加;年龄与AVN发生率呈负相关(r=-0.274, P=0.002)。股骨头直径与AVN分级呈显著负相关(P<0.005)。AVN分级与股骨头高度、有无骨核、骨核直径/高度、骨核与股骨头比例无显著相关性。结论脱位侧股骨头大小明显差于对侧股骨头大小。股骨头直径和骨核直径/高度随年龄增长而增加。AVN发生率与股骨头直径呈显著负相关。与股骨头高度和骨核大小无关。关键词:股骨头;髋关节;封闭的减少;股骨头缺血性坏死
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引用次数: 1
Application of telescopic rod during combined surgical technique for congenital pseudarthrosis of the tibia in children 伸缩杆在儿童先天性胫骨假关节联合手术技术中的应用
Q4 Medicine Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.0253-3006.2019.12.012
Yao-xi Liu, Kun Liu, Ge Yang, G. Zhu, Q. Tan, Jiang-yan Wu, W. Ye, A. Yan, Jin Tang
Objective To explore the preliminary effect of telescopic rod during combined surgical technique for congenital pseudarthrosis of the tibia (CPT) in children. Methods A retrospective study was performed for 15 children with Crawford type IV CPT undergoing combined surgical technique and telescopic rod from January 2017 to May 2018. There were 12 boys and 3 girls with an average operative age of 51.6 (16-126) months. The lesions were left (n=7) and right (n=8). The concurrent conditions were proximal tibia dysplasia (n=7) and neurofibromatosis type 1 (n=12). Combined surgical technique and telescopic rod included excision of pseudarthrosis, intramedullary rod insertion, installation of Ilizarov's fixator, tibio-fibular cross union and wrapping autogenic iliac bone graft. The incidence of refracture, ankle valgus, tibial valgus and limb length discrepancy (LLD) were recorded during an average follow-up period of 23.3(12-28) months. Results All children achieved primary union. The average primary union time was 4.5(4.0-5.6) months. Nine cases showed LLD with an average extremity length of 1.1(0.5-2.0) cm; ankle valgus (n=1; 18°) and proximal tibial valgus (n=3; 10°, 5° & 6°), telescopic rod displacement (n=6) and epiphyseal plate tethered (n=2). There was no instance of refracture during follow-ups. Movements of ankle joint were all normal with an average dorsiflexion 24°(20°~30°) and with an average plantar flexion 43°(40°~50°) and the function of ankle joint was normal. Conclusions The primary healing rate of CPT in children is high by operating with telescopic rod. However, intramedullary rod displacement still occurs. Key words: Children; Congenital pseudarthrosis of tibia; Telescopic rod; Initial effect
目的探讨伸缩杆在儿童先天性胫骨假关节(CPT)联合手术中的初步效果。方法回顾性分析2017年1月至2018年5月收治的15例Crawford IV型CPT患儿,采用联合手术技术和伸缩棒治疗。男12例,女3例,平均手术年龄51.6(16-126)个月。病变位于左侧(n=7)和右侧(n=8)。并发条件为胫骨近端发育不良(n=7)和1型神经纤维瘤病(n=12)。联合手术技术和伸缩棒包括假关节切除、髓内棒置入、Ilizarov固定架安装、胫腓骨交叉愈合和包裹自体髂骨移植物。在平均23.3(12-28)个月的随访期间,记录了再骨折、踝关节外翻、胫骨外翻和肢体长度差异(LLD)的发生率。结果所有患儿均达到初愈合。初愈合时间平均为4.5(4.0 ~ 5.6)个月。LLD 9例,四肢平均长度1.1(0.5 ~ 2.0)cm;踝关节外翻(n=1;18°)和胫骨近端外翻(n=3;10°,5°和6°),伸缩杆位移(n=6)和骨骺板系固(n=2)。随访期间无再骨折病例。踝关节活动正常,平均背屈24°(20°~30°),平均足底屈43°(40°~50°),踝关节功能正常。结论儿童CPT采用伸缩棒手术一期愈合率高。然而,仍会发生髓内棒移位。关键词:儿童;先天性胫骨假关节;伸缩杆;最初的效果
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引用次数: 0
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中华小儿外科杂志
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