首页 > 最新文献

Chinese Journal of Thoracic and Cardiovaescular Surgery最新文献

英文 中文
The value of video assisted thoracoscopic surgery of total thymectomy in the treatment of thymic tumor through subsagittal incision 胸腔镜下经矢状下切口全胸腺切除术治疗胸腺肿瘤的价值
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190524-00172
Qi-Fu Guo, Min Zheng, Ye Xu, Wenliang Qian, Chen Zhu, Ning Wang, Wen Zhao, Jing Yang
2018年3月至2019年3月期间采用剑突下切口胸腔镜全胸腺切除术治疗9例胸腺肿瘤患者,其中男6例,女3例;年龄24~83岁,平均(54.8±15.2)岁。患者术前均常规行胸部增强CT检查明确诊断,了解胸腺肿物与周围组织、血管关系,术前均未行肿物穿刺活检。全组手术过程顺利,无围手术期死亡,无输血、加用肋间切口和中转开胸。术后无迟发出血、肺部感染、肺不张、胸腔积液、胸腔或纵隔积气、重症肌无力等并发症。全组随访1~12个月,期间无肿瘤复发及特殊不适,疗效满意。经剑突下切口胸腔镜全胸腺切除术治疗胸腺肿瘤安全有效,创伤小,痛苦少,患者恢复快,值得临床推广应用。
2018年3月至2019年3月期间采用剑突下切口胸腔镜全胸腺切除术治疗9例胸腺肿瘤患者,其中男6例,女3例;年龄24~83岁,平均(54.8±15.2)岁。患者术前均常规行胸部增强CT检查明确诊断,了解胸腺肿物与周围组织、血管关系,术前均未行肿物穿刺活检。全组手术过程顺利,无围手术期死亡,无输血、加用肋间切口和中转开胸。术后无迟发出血、肺部感染、肺不张、胸腔积液、胸腔或纵隔积气、重症肌无力等并发症。全组随访1~12个月,期间无肿瘤复发及特殊不适,疗效满意。经剑突下切口胸腔镜全胸腺切除术治疗胸腺肿瘤安全有效,创伤小,痛苦少,患者恢复快,值得临床推广应用。
{"title":"The value of video assisted thoracoscopic surgery of total thymectomy in the treatment of thymic tumor through subsagittal incision","authors":"Qi-Fu Guo, Min Zheng, Ye Xu, Wenliang Qian, Chen Zhu, Ning Wang, Wen Zhao, Jing Yang","doi":"10.3760/CMA.J.CN112434-20190524-00172","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20190524-00172","url":null,"abstract":"2018年3月至2019年3月期间采用剑突下切口胸腔镜全胸腺切除术治疗9例胸腺肿瘤患者,其中男6例,女3例;年龄24~83岁,平均(54.8±15.2)岁。患者术前均常规行胸部增强CT检查明确诊断,了解胸腺肿物与周围组织、血管关系,术前均未行肿物穿刺活检。全组手术过程顺利,无围手术期死亡,无输血、加用肋间切口和中转开胸。术后无迟发出血、肺部感染、肺不张、胸腔积液、胸腔或纵隔积气、重症肌无力等并发症。全组随访1~12个月,期间无肿瘤复发及特殊不适,疗效满意。经剑突下切口胸腔镜全胸腺切除术治疗胸腺肿瘤安全有效,创伤小,痛苦少,患者恢复快,值得临床推广应用。","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"22 1","pages":"188-190"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83190415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative study of blood flow of in-situ BIMA in coronary artery bypass grafting 原位BIMA在冠状动脉旁路移植术中的围术期血流研究
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190723-00246
Zhou Zhao, Li-xue Zhang, Guo-dong Zhang, Xiangui Zhang, Xuan Wang, Junxue Gao, G. Fan, B. Lian, Jing Liu, Gang Liu, Shenglong Chen, Yu Chen
Objective To observate the changing trend of flow of in-situ bilateral internal mammary artery as grafts during perioperative period in patients undergoing coronary artery bypass grafting(CABG), and to compare the parameters of flow between LIMA and RIMA. Methods A total of 57 patients , 50 males and 7 femails, mean aged(57.8±10.1) years, underwent bilateral IMA CABG in our hospital from August 2016 to January 2019. Transthoracic ultrasound of IMA examination was performed before CABG. The blood flow, the PI(pulsation index) and other parameters were measured and recorded by intraoperative TTFM. Results There was no significant difference of the average diameter and PI between LIMA and RIMA, but the preoperative flow of RIMA is higher(P=0.026) in our study. There was no significant difference of the average flow and PI between LIMA and RIMA recorded by TTFM(P>0.05), but the higher diastolic flow(DF) in LIMA grafts(P=0.022) compared with RIMA grafts may be associated with the different target sites(P<0.05). Compared with the preoperative flow and PI of IMA, the intraoperative flow and PI of both LIMA and RIMA grafts were better(P<0.001). Conclusion Compared with the preoperative flow of IMA, both flow of LIMA and RIMA are better. In spite of the targets exist difference , there are no significant difference of the average flow and PI between LIMA graft and RIMA graft recorded by TTFM. Key words: Internal mammary artery; Coronary artery bypass grafting; Transit-time flowmeter; Transthoracic arterial ultrasound
目的观察原位双侧乳腺内动脉在冠状动脉旁路移植术(CABG)患者围手术期的血流变化趋势,并比较LIMA和RIMA的血流参数。方法2016年8月至2019年1月在我院行双侧IMA CABG患者57例,男50例,女7例,平均年龄(57.8±10.1)岁。CABG前行经胸超声检查IMA。术中TTFM测量并记录血流量、脉搏指数等参数。结果LIMA和RIMA的平均直径和PI无显著差异,但RIMA的术前流量更高(P=0.026)。TTFM记录LIMA和RIMA的平均血流和PI无显著差异(P<0.05),但LIMA移植血管的舒张血流(DF)高于RIMA移植血管(P=0.022)可能与不同的目标部位有关(P<0.05)。与IMA的术前血流和PI相比,LIMA和IMA的术中血流和PI更好(P<0.001)。结论与IMA术前的血流情况相比,LIMA和IMA的血流情况均较好。尽管目标存在差异,但TTFM记录的LIMA接枝和RIMA接枝的平均流量和PI无显著差异。关键词:乳腺内动脉;冠状动脉旁路移植术;渡越时间流量计;经胸动脉超声
{"title":"Perioperative study of blood flow of in-situ BIMA in coronary artery bypass grafting","authors":"Zhou Zhao, Li-xue Zhang, Guo-dong Zhang, Xiangui Zhang, Xuan Wang, Junxue Gao, G. Fan, B. Lian, Jing Liu, Gang Liu, Shenglong Chen, Yu Chen","doi":"10.3760/CMA.J.CN112434-20190723-00246","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20190723-00246","url":null,"abstract":"Objective \u0000To observate the changing trend of flow of in-situ bilateral internal mammary artery as grafts during perioperative period in patients undergoing coronary artery bypass grafting(CABG), and to compare the parameters of flow between LIMA and RIMA. \u0000 \u0000 \u0000Methods \u0000A total of 57 patients , 50 males and 7 femails, mean aged(57.8±10.1) years, underwent bilateral IMA CABG in our hospital from August 2016 to January 2019. Transthoracic ultrasound of IMA examination was performed before CABG. The blood flow, the PI(pulsation index) and other parameters were measured and recorded by intraoperative TTFM. \u0000 \u0000 \u0000Results \u0000There was no significant difference of the average diameter and PI between LIMA and RIMA, but the preoperative flow of RIMA is higher(P=0.026) in our study. There was no significant difference of the average flow and PI between LIMA and RIMA recorded by TTFM(P>0.05), but the higher diastolic flow(DF) in LIMA grafts(P=0.022) compared with RIMA grafts may be associated with the different target sites(P<0.05). Compared with the preoperative flow and PI of IMA, the intraoperative flow and PI of both LIMA and RIMA grafts were better(P<0.001). \u0000 \u0000 \u0000Conclusion \u0000Compared with the preoperative flow of IMA, both flow of LIMA and RIMA are better. In spite of the targets exist difference , there are no significant difference of the average flow and PI between LIMA graft and RIMA graft recorded by TTFM. \u0000 \u0000 \u0000Key words: \u0000Internal mammary artery; Coronary artery bypass grafting; Transit-time flowmeter; Transthoracic arterial ultrasound","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"16 1","pages":"175-179"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81689604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dialectical analysis of heparin residue in perioperative period of off-pump coronary artery bypass grafting 非体外循环冠状动脉旁路移植术围手术期肝素残留的辨证分析
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190521-00167
Dalei Guo, Yan Liu, P. Su, Xitao Zhang, Junbo Yan, Song Gu, Jie Gao, Y. Gou, Yue Xin, Qianwei Wang
Objective To investigate the best neutralization ratio of protamine and heparin during off-pump coronary artery bypass grafting(OPCABG) by analyzing the advantages and disadvantages of heparin residue after OPCABG. Methods From July 2018 to January 2019, 112 patients undergoing elective OPCABG were included in this study. The patients’ whole blood was drawn at 2 time points, including before entering operating room and entering intensive care unit, to receive thrombelastography(TEG) and heparinase-modified thromboelastography(hmTEG) . Conventional coagulation indexes such as activated coagulation time(ACT) were also detected. All the patients were divided into 3 groups, the non-heparin residue group(30 cases), heparin residue group 1(42 cases) and heparin residue group 2(40 cases) according to the laboratory results of TEG, hmTEG and ACT. We observed the dosage of each group of protamine and heparin, as well as the ratio of heparin and protamine. The changes of R time in TEG and ACT between 3 groups were analyzed and compared. Postoperative chest tube drainage at postoperative 12 h and 48 h, cTnI peak value, incidence of perioperative myocardial infarction(MI), incidence of reoperation and poor wound healing, amount of blood loss and transfusion, and acute renal injury were compared between the 3 groups. Results No significant trio-group differences existed in basic clinical characteristics(all P>0.05). Postoperative R(CKH)time was similar in the 3 groups(P>0.05). Comparing with heparin residue group 1 and heparin residue group 2, the ACT after protamine neutralizing heparin and postoperative R time were decreased, the dosage of protamine, ratio of heparin and protamine, cTnI peak value were increased in the non-heparin residue group(P 0.05). The perioperative myocardial infarction, incidence of reoperation and poor wound healing, postoperative acute renal injury and time of in ICU stay showed no significant differences between the 3 groups(P>0.05). Conclusion Moderate heparin residue after OPCAB suggests that it has myocardial protective effect, and does not significantly increase the risk of bleeding. A large number of heparin residues can affect the coagulation function and lead to bleeding tendency, increase the amount of blood loss and transfusion. It is reasonable to make ACT after protamine neutralize heparin higher than the level of ACT before operation, and not higher than 20% of the level before operation. Key words: Heparin; Protamine; Coronary artery bypass grafting, off-pump; Thromboelastograph
目的通过分析非体外循环冠状动脉搭桥术(OPCABG)术后肝素残留的优缺点,探讨鱼精蛋白与肝素的最佳中和比例。方法2018年7月至2019年1月,112例择期OPCABG患者纳入本研究。在进入手术室和进入重症监护病房前2个时间点抽取患者全血,分别进行血栓造影(TEG)和肝素酶修饰血栓弹性成像(hmTEG)。常规凝血指标如活化凝血时间(ACT)也进行检测。根据TEG、hmTEG、ACT检测结果将患者分为无肝素残留组(30例)、肝素残留1组(42例)、肝素残留2组(40例)。观察各组鱼精蛋白与肝素的用量及肝素与鱼精蛋白的比值。分析比较3组间TEG、ACT R时间的变化。比较三组患者术后12 h、48 h胸管引流、cTnI峰值、围手术期心肌梗死发生率、再手术发生率及创面愈合不良发生率、失血量及输血量、急性肾损伤情况。结果三组患者基本临床特征比较差异无统计学意义(P>0.05)。3组患者术后R(CKH)时间比较,差异无统计学意义(P>0.05)。与肝素残留1组和肝素残留2组比较,非肝素残留组鱼精蛋白中和肝素后的ACT和术后R时间均降低,鱼精蛋白用量、肝素与鱼精蛋白比值、cTnI峰值均升高(P < 0.05)。三组患者围手术期心肌梗死、再手术及伤口愈合不良发生率、术后急性肾损伤及ICU住院时间比较,差异均无统计学意义(P>0.05)。结论OPCAB术后肝素残留量适中,具有心肌保护作用,不明显增加出血风险。大量肝素残留可影响凝血功能,导致出血倾向,增加失血量和输血。鱼精蛋白中和肝素后的ACT应高于术前ACT水平,且不高于术前水平的20%。关键词:肝素;鱼精蛋白;冠状动脉旁路移植术;Thromboelastograph
{"title":"Dialectical analysis of heparin residue in perioperative period of off-pump coronary artery bypass grafting","authors":"Dalei Guo, Yan Liu, P. Su, Xitao Zhang, Junbo Yan, Song Gu, Jie Gao, Y. Gou, Yue Xin, Qianwei Wang","doi":"10.3760/CMA.J.CN112434-20190521-00167","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20190521-00167","url":null,"abstract":"Objective \u0000To investigate the best neutralization ratio of protamine and heparin during off-pump coronary artery bypass grafting(OPCABG) by analyzing the advantages and disadvantages of heparin residue after OPCABG. \u0000 \u0000 \u0000Methods \u0000From July 2018 to January 2019, 112 patients undergoing elective OPCABG were included in this study. The patients’ whole blood was drawn at 2 time points, including before entering operating room and entering intensive care unit, to receive thrombelastography(TEG) and heparinase-modified thromboelastography(hmTEG) . Conventional coagulation indexes such as activated coagulation time(ACT) were also detected. All the patients were divided into 3 groups, the non-heparin residue group(30 cases), heparin residue group 1(42 cases) and heparin residue group 2(40 cases) according to the laboratory results of TEG, hmTEG and ACT. We observed the dosage of each group of protamine and heparin, as well as the ratio of heparin and protamine. The changes of R time in TEG and ACT between 3 groups were analyzed and compared. Postoperative chest tube drainage at postoperative 12 h and 48 h, cTnI peak value, incidence of perioperative myocardial infarction(MI), incidence of reoperation and poor wound healing, amount of blood loss and transfusion, and acute renal injury were compared between the 3 groups. \u0000 \u0000 \u0000Results \u0000No significant trio-group differences existed in basic clinical characteristics(all P>0.05). Postoperative R(CKH)time was similar in the 3 groups(P>0.05). Comparing with heparin residue group 1 and heparin residue group 2, the ACT after protamine neutralizing heparin and postoperative R time were decreased, the dosage of protamine, ratio of heparin and protamine, cTnI peak value were increased in the non-heparin residue group(P 0.05). The perioperative myocardial infarction, incidence of reoperation and poor wound healing, postoperative acute renal injury and time of in ICU stay showed no significant differences between the 3 groups(P>0.05). \u0000 \u0000 \u0000Conclusion \u0000Moderate heparin residue after OPCAB suggests that it has myocardial protective effect, and does not significantly increase the risk of bleeding. A large number of heparin residues can affect the coagulation function and lead to bleeding tendency, increase the amount of blood loss and transfusion. It is reasonable to make ACT after protamine neutralize heparin higher than the level of ACT before operation, and not higher than 20% of the level before operation. \u0000 \u0000 \u0000Key words: \u0000Heparin; Protamine; Coronary artery bypass grafting, off-pump; Thromboelastograph","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"50 1","pages":"180-184"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88185288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Result of surgical treatment of obstructive hypertrophic cardiomyopathy with atrial fibrillation 梗阻性肥厚性心肌病合并心房颤动的手术治疗效果
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.010
Yanhai Meng, Ping Liu, Yanbo Zhang, Qinjun Yu, Shengwei Wang, Changsheng Zhu, Shuiyun Wang
2015年1月至2018年6月采用改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗肥厚型梗阻性心肌病(HOCM)合并房颤(AF)患者43例。围手术期死亡2例。超声心动图显示生存患者术后左心室流出道压差明显降低(P<0.01),SAM征均消失。随访6~60个月,平均(21.88±12.09)个月,期间无死亡,无再次手术患者,患者心功能(NYHA分级)Ⅰ~Ⅱ级。随访终点时窦性心律维持率75.61%(31/41),经药物控制后窦性心律维持率87.80%(36/41)。Morrow/Cox-maze Ⅳ术后1年AF免于复发率(82.1±6.2)%,3年免于复发率(71.8±7.7)%。应用药物控制后,1年窦性心律维持率(89.7±4.9)%, 3年AF免于复发率(83.3±7.7)%。本组研究结果显示,改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗HOCM合并AF安全有效。术后窦性心律维持率可维持在满意水平,患者心功能和生活质量明显改善。应用药物控制可提高Morrow/Cox-maze Ⅳ术后窦性心律维持率。
2015年1月至2018年6月采用改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗肥厚型梗阻性心肌病(HOCM)合并房颤(AF)患者43例。围手术期死亡2例。超声心动图显示生存患者术后左心室流出道压差明显降低(P<0.01),SAM征均消失。随访6~60个月,平均(21.88±12.09)个月,期间无死亡,无再次手术患者,患者心功能(NYHA分级)Ⅰ~Ⅱ级。随访终点时窦性心律维持率75.61%(31/41),经药物控制后窦性心律维持率87.80%(36/41)。Morrow/Cox-maze Ⅳ术后1年AF免于复发率(82.1±6.2)%,3年免于复发率(71.8±7.7)%。应用药物控制后,1年窦性心律维持率(89.7±4.9)%, 3年AF免于复发率(83.3±7.7)%。本组研究结果显示,改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗HOCM合并AF安全有效。术后窦性心律维持率可维持在满意水平,患者心功能和生活质量明显改善。应用药物控制可提高Morrow/Cox-maze Ⅳ术后窦性心律维持率。
{"title":"Result of surgical treatment of obstructive hypertrophic cardiomyopathy with atrial fibrillation","authors":"Yanhai Meng, Ping Liu, Yanbo Zhang, Qinjun Yu, Shengwei Wang, Changsheng Zhu, Shuiyun Wang","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.010","url":null,"abstract":"2015年1月至2018年6月采用改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗肥厚型梗阻性心肌病(HOCM)合并房颤(AF)患者43例。围手术期死亡2例。超声心动图显示生存患者术后左心室流出道压差明显降低(P<0.01),SAM征均消失。随访6~60个月,平均(21.88±12.09)个月,期间无死亡,无再次手术患者,患者心功能(NYHA分级)Ⅰ~Ⅱ级。随访终点时窦性心律维持率75.61%(31/41),经药物控制后窦性心律维持率87.80%(36/41)。Morrow/Cox-maze Ⅳ术后1年AF免于复发率(82.1±6.2)%,3年免于复发率(71.8±7.7)%。应用药物控制后,1年窦性心律维持率(89.7±4.9)%, 3年AF免于复发率(83.3±7.7)%。本组研究结果显示,改良扩大Morrow术同期行Cox-maze Ⅳ手术治疗HOCM合并AF安全有效。术后窦性心律维持率可维持在满意水平,患者心功能和生活质量明显改善。应用药物控制可提高Morrow/Cox-maze Ⅳ术后窦性心律维持率。","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"115 1","pages":"111-114"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78343972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video-assisted thoracoscopic septal myectomy for hypertrophic obstructive cardiomyopathy in 4 cases 电视胸腔镜下室间隔肌切除术治疗肥厚性梗阻性心肌病4例
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.008
Shuwei Wang, B. Zhou, Yong Cui, Zhifang Liu, Changhao Wu, F. Mei, Zhi-Bin Hu
回顾性分析2016年11月至2019年5月在本院收治的4例肥厚型梗阻性心肌病(HOCM)合并二尖瓣关闭不全患者的临床资料。患者均接受胸腔镜辅助下经右侧腋下小切口(5 cm)手术,股动静脉插管建立体外循环,经左心房和二尖瓣前叶基部切口行胸腔镜辅助下室间隔心肌切除术(SM)并二尖瓣成形术。全组患者均顺利完成手术,无术后心力衰竭、恶性心律失常和低氧血症等并发症。术后经胸超声心动图随访结果提示左心室流出道梗阻解除满意,二尖瓣闭合功能良好。随访期内无需要再次手术干预的患者。胸腔镜辅助右腋下小切口治疗HOCM是安全可行的,可以为解除左心室流出道梗阻和二尖瓣及瓣下装置的异常提供良好的手术视野。
回顾性分析2016年11月至2019年5月在本院收治的4例肥厚型梗阻性心肌病(HOCM)合并二尖瓣关闭不全患者的临床资料。患者均接受胸腔镜辅助下经右侧腋下小切口(5 cm)手术,股动静脉插管建立体外循环,经左心房和二尖瓣前叶基部切口行胸腔镜辅助下室间隔心肌切除术(SM)并二尖瓣成形术。全组患者均顺利完成手术,无术后心力衰竭、恶性心律失常和低氧血症等并发症。术后经胸超声心动图随访结果提示左心室流出道梗阻解除满意,二尖瓣闭合功能良好。随访期内无需要再次手术干预的患者。胸腔镜辅助右腋下小切口治疗HOCM是安全可行的,可以为解除左心室流出道梗阻和二尖瓣及瓣下装置的异常提供良好的手术视野。
{"title":"Video-assisted thoracoscopic septal myectomy for hypertrophic obstructive cardiomyopathy in 4 cases","authors":"Shuwei Wang, B. Zhou, Yong Cui, Zhifang Liu, Changhao Wu, F. Mei, Zhi-Bin Hu","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.008","url":null,"abstract":"回顾性分析2016年11月至2019年5月在本院收治的4例肥厚型梗阻性心肌病(HOCM)合并二尖瓣关闭不全患者的临床资料。患者均接受胸腔镜辅助下经右侧腋下小切口(5 cm)手术,股动静脉插管建立体外循环,经左心房和二尖瓣前叶基部切口行胸腔镜辅助下室间隔心肌切除术(SM)并二尖瓣成形术。全组患者均顺利完成手术,无术后心力衰竭、恶性心律失常和低氧血症等并发症。术后经胸超声心动图随访结果提示左心室流出道梗阻解除满意,二尖瓣闭合功能良好。随访期内无需要再次手术干预的患者。胸腔镜辅助右腋下小切口治疗HOCM是安全可行的,可以为解除左心室流出道梗阻和二尖瓣及瓣下装置的异常提供良好的手术视野。","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"15 1","pages":"104-106"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81868201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment strategy for traumatic aortic injury 外伤性主动脉损伤的外科治疗策略
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.003
Suwei Chen, Yongliang Zhong, Chengnan Li, Y. Ge, Z. Qiao, R. Qi, Haiou Hu, Junming Zhu, Li-Zhong Sun
Objective To summarize the surgical treatment strategy for aortic injury caused by trauma. Methods From January 2009 to January 2018, 34 patients with TAI were treated in Beijing Anzhen Hospital. 10 had hypertension. 23 cases were males. There were 31 cases caused by traffic accidents, 2 cases were fall injuries, and 1 case was bruise. 9 cases were thoracic aortic pseudoaneurysm, 6 cases were thoracic aorta, and 19 cases were aortic dissection. 29 patients underwent TEVAR and 5 patients underwent OR (2 patients with type A aortic dissection undergoing Bentall + Sun's procedure, 1 patient with type B aortic dissection and 2 patients with thoracic aortic pseudoaneurysm undergoing stented elephant trunk procedure). Results The follow-up time was (45.09±23.10) months. The mean age of patients undergoing OR or TEVAR was (44.80±20.57) years old, (45.93±11.01) years old; the mean operation time was(403.20±30.30) minutes, (105.72±27.76) minutes; the mean hospitalization (19.00±6.04), (5.76±3.08) days. There were no deaths in the two groups. 2 patients uundergoing TEVAR had left upper limb numbness. Conclusion The treatment of patients with TAI should be based on the general condition, the classification of injury, the involving regions and anatomical features to choose different treatments. In addition, the long-term prognosis of patients remains to be determined. Key words: Aortic disease; Trauma; Stented elephant trunk procedure; Thoracic aortic endovascular repair
目的总结外伤性主动脉损伤的外科治疗策略。方法2009年1月至2018年1月,在北京安贞医院收治34例TAI患者,其中10例合并高血压。男性23例。交通事故致伤31例,摔伤2例,瘀伤1例。胸主动脉假性动脉瘤9例,胸主动脉6例,主动脉夹层19例。29例患者行TEVAR手术,5例患者行OR手术(A型主动脉夹层2例行Bentall + Sun手术,B型主动脉夹层1例,胸主动脉假性动脉瘤2例行支架象鼻手术)。结果随访时间为(45.09±23.10)个月。接受OR或TEVAR的患者平均年龄分别为(44.80±20.57)岁、(45.93±11.01)岁;平均手术时间分别为(403.20±30.30)min、(105.72±27.76)min;平均住院时间(19.00±6.04)天,(5.76±3.08)天。两组均无死亡病例。2例TEVAR术后出现左上肢麻木。结论TAI患者的治疗应根据患者的一般情况、损伤类型、受累部位及解剖特征选择不同的治疗方法。此外,患者的长期预后仍有待确定。关键词:主动脉疾病;创伤;象鼻支架手术;胸主动脉血管内修复
{"title":"Surgical treatment strategy for traumatic aortic injury","authors":"Suwei Chen, Yongliang Zhong, Chengnan Li, Y. Ge, Z. Qiao, R. Qi, Haiou Hu, Junming Zhu, Li-Zhong Sun","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.003","url":null,"abstract":"Objective \u0000To summarize the surgical treatment strategy for aortic injury caused by trauma. \u0000 \u0000 \u0000Methods \u0000From January 2009 to January 2018, 34 patients with TAI were treated in Beijing Anzhen Hospital. 10 had hypertension. 23 cases were males. There were 31 cases caused by traffic accidents, 2 cases were fall injuries, and 1 case was bruise. 9 cases were thoracic aortic pseudoaneurysm, 6 cases were thoracic aorta, and 19 cases were aortic dissection. 29 patients underwent TEVAR and 5 patients underwent OR (2 patients with type A aortic dissection undergoing Bentall + Sun's procedure, 1 patient with type B aortic dissection and 2 patients with thoracic aortic pseudoaneurysm undergoing stented elephant trunk procedure). \u0000 \u0000 \u0000Results \u0000The follow-up time was (45.09±23.10) months. The mean age of patients undergoing OR or TEVAR was (44.80±20.57) years old, (45.93±11.01) years old; the mean operation time was(403.20±30.30) minutes, (105.72±27.76) minutes; the mean hospitalization (19.00±6.04), (5.76±3.08) days. There were no deaths in the two groups. 2 patients uundergoing TEVAR had left upper limb numbness. \u0000 \u0000 \u0000Conclusion \u0000The treatment of patients with TAI should be based on the general condition, the classification of injury, the involving regions and anatomical features to choose different treatments. In addition, the long-term prognosis of patients remains to be determined. \u0000 \u0000 \u0000Key words: \u0000Aortic disease; Trauma; Stented elephant trunk procedure; Thoracic aortic endovascular repair","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"9 1","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75635769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical characteristics and safety of valvular surgery in elderly patients aged over 75 years 75岁以上老年患者瓣膜手术的临床特点及安全性
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.002
Bing Liu, Shengli Jiang, Lin Zhang
Objective To study the clinical characteristics and surgical conditions of valve surgery in elderly patients over 75 years old. Methods Datas of patients over 75 years old with valve surgery in our hospital from January 2014 to January 2019 were retrospectively analyzed. 73 cases were analyzed, accounting for 5.3%(73/1 372) of the cardiac valve operations performed during the same period.There were 46 males and 27 females, with an average age of 77.35 years(75-88 years). The main diagnoses were MR 28 cases(38.3%), MS 8 cases(11.0%), AR 7 cases(9.6%), AS+ AR 7 cases(9.6%) and AS 6 cases (8.2%). There were 28 cases(38.4%) of MVR+ TVP, 20 cases(27.4%) of AVR, and 11 cases(15.1%) of MVR.Pacemakers were installed in 2 patients(2.7%) and coronary artery bypass grafting was performed in 14 patients(19.2%). Results There were statistically significant differences in left atrial end-diastolic diameter(LA), left ventricular end-diastolic diameter(LV), right atrial end-diastolic diameter(RA) and ejection fraction(EF) before and after surgery(P 0.05) in surgical interception time, extracorporeal circulation time, postoperative ventilator time, ICU time, surgical complications, postoperative liver and kidney functioninsufficiencyand mortality, as compared with 150 cases of valve surgery under 60 years old(P>0.05). Conclusion Mitral regurgitation is the most common valvular disease in senile patients over 75 years old, the cardiac structure is improved significantly after surgery, and the risk of surgery is the same as that in normal age groups. Therefore, valvular surgery issafe in elderly patients over 75 years old. Key words: Senile valve; Clinical characteristics; Surgery; Safety
目的探讨75岁以上老年人瓣膜手术的临床特点及手术条件。方法回顾性分析2014年1月至2019年1月我院75岁以上瓣膜手术患者的资料。共分析73例,占同期心脏瓣膜手术的5.3%(73/1 372)。男性46例,女性27例,平均年龄77.35岁(75 ~ 88岁)。主要诊断为MR 28例(38.3%)、MS 8例(11.0%)、AR 7例(9.6%)、AS+ AR 7例(9.6%)、AS 6例(8.2%)。MVR+ TVP 28例(38.4%),AVR 20例(27.4%),MVR 11例(15.1%)。2例(2.7%)患者安装起搏器,14例(19.2%)患者行冠状动脉旁路移植术。结果两组患者术前、术后左房舒张末期内径(LA)、左室舒张末期内径(LV)、右房舒张末期内径(RA)、射血分数(EF)在手术截流时间、体外循环时间、术后呼吸机时间、ICU时间、手术并发症、术后肝肾功能不全、死亡率等方面差异均有统计学意义(P < 0.05)。与150例60岁以下瓣膜手术相比(P>0.05)。结论二尖瓣反流是75岁以上老年患者最常见的瓣膜疾病,手术后心脏结构明显改善,手术风险与正常年龄组相同。因此,对于75岁以上的老年患者,瓣膜手术是安全的。关键词:老年阀;临床特点;手术;安全
{"title":"Clinical characteristics and safety of valvular surgery in elderly patients aged over 75 years","authors":"Bing Liu, Shengli Jiang, Lin Zhang","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.002","url":null,"abstract":"Objective \u0000To study the clinical characteristics and surgical conditions of valve surgery in elderly patients over 75 years old. \u0000 \u0000 \u0000Methods \u0000Datas of patients over 75 years old with valve surgery in our hospital from January 2014 to January 2019 were retrospectively analyzed. 73 cases were analyzed, accounting for 5.3%(73/1 372) of the cardiac valve operations performed during the same period.There were 46 males and 27 females, with an average age of 77.35 years(75-88 years). The main diagnoses were MR 28 cases(38.3%), MS 8 cases(11.0%), AR 7 cases(9.6%), AS+ AR 7 cases(9.6%) and AS 6 cases (8.2%). There were 28 cases(38.4%) of MVR+ TVP, 20 cases(27.4%) of AVR, and 11 cases(15.1%) of MVR.Pacemakers were installed in 2 patients(2.7%) and coronary artery bypass grafting was performed in 14 patients(19.2%). \u0000 \u0000 \u0000Results \u0000There were statistically significant differences in left atrial end-diastolic diameter(LA), left ventricular end-diastolic diameter(LV), right atrial end-diastolic diameter(RA) and ejection fraction(EF) before and after surgery(P 0.05) in surgical interception time, extracorporeal circulation time, postoperative ventilator time, ICU time, surgical complications, postoperative liver and kidney functioninsufficiencyand mortality, as compared with 150 cases of valve surgery under 60 years old(P>0.05). \u0000 \u0000 \u0000Conclusion \u0000Mitral regurgitation is the most common valvular disease in senile patients over 75 years old, the cardiac structure is improved significantly after surgery, and the risk of surgery is the same as that in normal age groups. Therefore, valvular surgery issafe in elderly patients over 75 years old. \u0000 \u0000 \u0000Key words: \u0000Senile valve; Clinical characteristics; Surgery; Safety","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"15 1","pages":"74-78"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73565962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discovery of tracheal diverticulum using HRCT scan in patients with chronic cough: four cases report and literature review 慢性咳嗽患者HRCT扫描发现气管憩室4例报告并文献复习
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.009
Qi-Fu Guo, Min Zheng, Ye Xu, Wenliang Qian, Chen Zhu, Ning Wang, Wen Zhao, Jing Yang
对2018年8月至2019年3月上海交通大学医学院附属同仁医院诊治的4例气管憩室导致慢性咳嗽患者的临床和病理资料进行分析,胸部高分辨HRCT检查显示,胸廓入口处气管旁右侧后壁的类圆形或不规则囊状或柱状气体影,连续横断薄层扫描或多平面重建等后处理技术发现气囊与气管之间无或有一较细的管道相连,气管镜检查均未见明显异常通道,术后病理报告示气管憩室。经颈部沿皮纹横弧形切口顺利切除气管憩室,术后慢性咳嗽症状消退,随访2~8个月,疗效满意。
对2018年8月至2019年3月上海交通大学医学院附属同仁医院诊治的4例气管憩室导致慢性咳嗽患者的临床和病理资料进行分析,胸部高分辨HRCT检查显示,胸廓入口处气管旁右侧后壁的类圆形或不规则囊状或柱状气体影,连续横断薄层扫描或多平面重建等后处理技术发现气囊与气管之间无或有一较细的管道相连,气管镜检查均未见明显异常通道,术后病理报告示气管憩室。经颈部沿皮纹横弧形切口顺利切除气管憩室,术后慢性咳嗽症状消退,随访2~8个月,疗效满意。
{"title":"Discovery of tracheal diverticulum using HRCT scan in patients with chronic cough: four cases report and literature review","authors":"Qi-Fu Guo, Min Zheng, Ye Xu, Wenliang Qian, Chen Zhu, Ning Wang, Wen Zhao, Jing Yang","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.009","url":null,"abstract":"对2018年8月至2019年3月上海交通大学医学院附属同仁医院诊治的4例气管憩室导致慢性咳嗽患者的临床和病理资料进行分析,胸部高分辨HRCT检查显示,胸廓入口处气管旁右侧后壁的类圆形或不规则囊状或柱状气体影,连续横断薄层扫描或多平面重建等后处理技术发现气囊与气管之间无或有一较细的管道相连,气管镜检查均未见明显异常通道,术后病理报告示气管憩室。经颈部沿皮纹横弧形切口顺利切除气管憩室,术后慢性咳嗽症状消退,随访2~8个月,疗效满意。","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"55 1","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74813294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of ballon atrial septostomy for left heart venting during extracorporeal membrane oxygenation 体外膜氧合中球囊房间隔造口术在左心通气中的应用
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.005
Dingyang Li, Gangcheng Zhang, Q. Shen, Yan Liu, Naiwen Cao, Yueting Zhou
Objective To discuss whether balloon atrial septostomy(BAS) can provide safe and effective left ventricular venting for venoarterial extracorporeal membrane oxygenation(V-A ECMO). Methods From March 2017 to January 2019, 9 patients received BAS for left ventricular venting during V-A ECMO treatment in our hospital, including 5 males and 4 females, aged 12-72 years. There were 3 cases of severe myocarditis, 4 cases of low cardiac output after cardiac surgery, and 2 cases of acute myocardial infarction. Basic data, procedure data, outcome and follow-up were recorded. Results BAS were successfully performed in 9 patients. Procedure time on average was 42.2 min. Anterior mediastinal hematoma occurred in 1 case. There were no other procedure-related complications in the rest cases. No pulmonary edema or thrombosis occurred in all 9 cases during ECMO. No closure procedure was performed. Conclusion BAS is a safe and effective method for left ventricular venting. The procedure is conductive to the recovery of patients with severe left heart failure. Key words: Atrial septostomy; Transseptal puncture; Extracorporeal membrane oxygenation; Left ventricular venting
目的探讨球囊房间隔造口术(BAS)能否为静脉动脉体外膜氧合(V-A ECMO)提供安全有效的左心室通气。方法2017年3月至2019年1月,我院V-A ECMO治疗期间接受BAS治疗左室通气的患者9例,男5例,女4例,年龄12-72岁。心脏手术后发生严重心肌炎3例,心输出量低4例,急性心肌梗死2例。记录基本资料、手术资料、结果及随访情况。结果9例患者成功行BAS手术。手术时间平均42.2 min,前纵隔血肿1例。其余病例无其他手术相关并发症。9例患者在ECMO过程中均未发生肺水肿和血栓形成。未执行闭合程序。结论BAS是一种安全、有效的左心室通气方法。该手术有助于严重左心衰竭患者的康复。关键词:房间隔造口术;Transseptal穿刺;体外膜氧合;左心室通气
{"title":"Application of ballon atrial septostomy for left heart venting during extracorporeal membrane oxygenation","authors":"Dingyang Li, Gangcheng Zhang, Q. Shen, Yan Liu, Naiwen Cao, Yueting Zhou","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.005","url":null,"abstract":"Objective \u0000To discuss whether balloon atrial septostomy(BAS) can provide safe and effective left ventricular venting for venoarterial extracorporeal membrane oxygenation(V-A ECMO). \u0000 \u0000 \u0000Methods \u0000From March 2017 to January 2019, 9 patients received BAS for left ventricular venting during V-A ECMO treatment in our hospital, including 5 males and 4 females, aged 12-72 years. There were 3 cases of severe myocarditis, 4 cases of low cardiac output after cardiac surgery, and 2 cases of acute myocardial infarction. Basic data, procedure data, outcome and follow-up were recorded. \u0000 \u0000 \u0000Results \u0000BAS were successfully performed in 9 patients. Procedure time on average was 42.2 min. Anterior mediastinal hematoma occurred in 1 case. There were no other procedure-related complications in the rest cases. No pulmonary edema or thrombosis occurred in all 9 cases during ECMO. No closure procedure was performed. \u0000 \u0000 \u0000Conclusion \u0000BAS is a safe and effective method for left ventricular venting. The procedure is conductive to the recovery of patients with severe left heart failure. \u0000 \u0000 \u0000Key words: \u0000Atrial septostomy; Transseptal puncture; Extracorporeal membrane oxygenation; Left ventricular venting","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"99 41 1","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85744252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on the coronary endarterectomy combined with electrocautery in the treatment of diffuse coronary artery disease 冠状动脉内膜切除术联合电灼治疗弥漫性冠状动脉病变的研究
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1001-4497.2020.02.004
Chuan Wang, Tongxun Li, Fan Zhang, C. Gu, Jing-xing Li
Objective To explore the outcomes and mechanisms of coronary endarterectomy combined with electrocautery in patients with diffused coronary artery disease undergoing coronary artery bypass grafting (CABG). Methods From January 2017 to September 2018, 300 patients undergoing CABG with left anterior descending artery endarterectomy were randomly divided into two groups, after fully informed the risks and other related issues regarding the operations. All the patients in the two groups were treated with CABG. In the study group, patients underwent electrocautery immediately after endarterectomy, whereas in the control group, patients underwent endarterectomy only. The electrocardiogram and serological examination (TNI, IL-6 and TNF-a) were performed at 2 h, 24 h, 72 h and 120 h after operation. The follow-up duration was 1 year. Results Nine patients in the study group, and 25 patients in the control group had ST segment elevation. The levels of TNI, IL-6 and TNF-a were continuously increased in both groups, and reached the peak at 24 h, then decreased slowly. The levels of TNF-a were significantly lower at 2 h postoperatively in the study group (P=0.01). There was no significant difference in the levels of TNI and IL-6 between the two groups. The levels of TNI, TNF-a and IL-6 were significantly lower in the electrocautery group at 24 h, 72 h, and 120 h after operation(P<0.05). One year after operation, incidences of ST segment elevation in the study group were significantly lower than that in the control group, and there was no significant difference in restenosis rate and myocardial infarction rate. Conclusion Endarterectomy combined with electrocautery may prevent the restenosis of the lumen and blood turbulence, smooth the inner wall of the vessel, slow down the release of inflammatory factors in the peripheral blood, inhibit the expression of inflammatory factors in the vessels, and reduce the myocardial damage. The short-term effect was satisfactory; the long-term anti-inflammatory and antithrombotic effect still need further investigations. Key words: Endarterectomy; Electrocautery; Inflammatory response; Thrombosis
目的探讨弥漫性冠状动脉病变行冠状动脉搭桥术(CABG)患者行冠状动脉内膜切除术联合电切术的疗效及机制。方法选取2017年1月至2018年9月行CABG合并左前降支内膜切除术的300例患者,在充分告知手术风险及相关问题后,随机分为两组。两组患者均行冠脉搭桥治疗。在研究组中,患者在动脉内膜切除术后立即进行电灼,而在对照组中,患者仅进行动脉内膜切除术。分别于术后2 h、24 h、72 h、120 h进行心电图和血清学检查(TNI、IL-6、TNF-a)。随访时间为1年。结果研究组9例,对照组25例出现ST段抬高。两组TNI、IL-6、TNF-a水平均持续升高,并在24 h达到峰值,随后缓慢下降。研究组术后2 h TNF-a水平明显低于对照组(P=0.01)。两组间TNI和IL-6水平无显著差异。电灼组患者术后24 h、72 h、120 h TNI、TNF-a、IL-6水平均显著低于对照组(P<0.05)。术后1年研究组ST段抬高发生率明显低于对照组,再狭窄率和心肌梗死率差异无统计学意义。结论电切联合动脉内膜切除术可防止管腔再狭窄和血流动荡,使血管内壁光滑,减缓外周血中炎症因子的释放,抑制血管中炎症因子的表达,减轻心肌损伤。短期效果令人满意;其长期抗炎和抗血栓作用仍需进一步研究。关键词:动脉内膜切除术;电烙术;炎症反应;血栓形成
{"title":"Study on the coronary endarterectomy combined with electrocautery in the treatment of diffuse coronary artery disease","authors":"Chuan Wang, Tongxun Li, Fan Zhang, C. Gu, Jing-xing Li","doi":"10.3760/CMA.J.ISSN.1001-4497.2020.02.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1001-4497.2020.02.004","url":null,"abstract":"Objective To explore the outcomes and mechanisms of coronary endarterectomy combined with electrocautery in patients with diffused coronary artery disease undergoing coronary artery bypass grafting (CABG). Methods From January 2017 to September 2018, 300 patients undergoing CABG with left anterior descending artery endarterectomy were randomly divided into two groups, after fully informed the risks and other related issues regarding the operations. All the patients in the two groups were treated with CABG. In the study group, patients underwent electrocautery immediately after endarterectomy, whereas in the control group, patients underwent endarterectomy only. The electrocardiogram and serological examination (TNI, IL-6 and TNF-a) were performed at 2 h, 24 h, 72 h and 120 h after operation. The follow-up duration was 1 year. Results Nine patients in the study group, and 25 patients in the control group had ST segment elevation. The levels of TNI, IL-6 and TNF-a were continuously increased in both groups, and reached the peak at 24 h, then decreased slowly. The levels of TNF-a were significantly lower at 2 h postoperatively in the study group (P=0.01). There was no significant difference in the levels of TNI and IL-6 between the two groups. The levels of TNI, TNF-a and IL-6 were significantly lower in the electrocautery group at 24 h, 72 h, and 120 h after operation(P<0.05). One year after operation, incidences of ST segment elevation in the study group were significantly lower than that in the control group, and there was no significant difference in restenosis rate and myocardial infarction rate. Conclusion Endarterectomy combined with electrocautery may prevent the restenosis of the lumen and blood turbulence, smooth the inner wall of the vessel, slow down the release of inflammatory factors in the peripheral blood, inhibit the expression of inflammatory factors in the vessels, and reduce the myocardial damage. The short-term effect was satisfactory; the long-term anti-inflammatory and antithrombotic effect still need further investigations. Key words: Endarterectomy; Electrocautery; Inflammatory response; Thrombosis","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"278 1","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76820563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Chinese Journal of Thoracic and Cardiovaescular Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1