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[Reflections on external circulatory assistance. Apropos of 8 patients treated with the MEDOS system]. 对体外循环辅助的思考。8例使用MEDOS系统治疗的患者]。
J P Villemot, J P Carteaux, N Bischoff, P M Mertes, D Longrois, T Hubert, M F Mattei, T Lecompte

Mechanical circulatory support is required when cardiogenic shock is unresponsive to well conducted medical therapy. In this hemodynamic situation, when the patient's life is in danger, within hours, several questions should be answered quickly. These questions take into consideration the etiologies of cardiogenic shock and are related to the possibility of improvement of myocardial function, cardiac transplantation, the choice of uni- or biventricular support and surgical techniques of left ventricular assistance (left atrium to aorta or left ventricular apex to aorta). The follow-up of patients with circulatory support is complex. It requires to take into consideration hemodynamic, mechanical and hemobiological parameters as well as the peripheric organ function. We report in this article our clinical experience with eight patients that underwent circulatory support with Medos external ventricular assist device.

当心源性休克对良好的药物治疗无反应时,需要机械循环支持。在这种血流动力学的情况下,当病人的生命处于危险之中时,几个小时内,几个问题应该迅速得到回答。这些问题考虑到心源性休克的病因,并与心肌功能改善的可能性、心脏移植、单心室或双心室支持的选择以及左心室辅助手术技术(左心房到主动脉或左心室心尖到主动脉)有关。循环支持患者的随访是复杂的。它需要考虑血液动力学、力学和血液生物学参数以及外周器官的功能。我们在这篇文章中报告了8例使用Medos外心室辅助装置进行循环支持的患者的临床经验。
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引用次数: 0
[Modularity of prostheses]. [假体的模块化]。
J N Argenson, M Kacem-Boudhar, J M Aubaniac

Modularity allows a large choice of implants, like the use of cementless acetabular cups inducing bone ingrowth. The length and direction of the neck may also be adapted to be new joint. Risks of modularity are: implant dissociation, restriction of joint mobility, and especially augmentation of metal debris as a potential source of polyethylene wear. It is then critical to play attention to implant design, material choice and planning of the arthroplasty.

模块化允许大量选择的植入物,如使用无水泥的髋臼杯诱导骨向内生长。颈部的长度和方向也可以适应为新关节。模块化的风险是:植入物分离,关节活动受限,特别是金属碎片的增加,作为聚乙烯磨损的潜在来源。因此,关注假体的设计、材料的选择和关节置换术的规划是至关重要的。
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引用次数: 0
[Richter's spinofixation in vaginal prolapse]. [Richter脊柱固定术治疗阴道脱垂]。
J Giuly, L Cravello, C D'Ercole, V Roger, G Porcu, B Blanc

The transvaginal sacrospinous fixation, called Richter operation was initially aimed to cure vaginal vault prolapse after hysterectomy. The results are as good as those of the abdominal promontory fixation with the well known advantages of the vaginal route. Indications way be extended to V3 U3 R3 prolapse and cure of elytrocele with good results in our practice. In few cases remnant cystocele may be a trouble some problem.

经阴道骶棘固定,称为Richter手术,最初旨在治疗子宫切除术后阴道穹窿脱垂。其效果与经阴道入路的腹角固定一样好。将适应症扩展到V3、U3、R3脱垂治疗鞘翅鞘,在实践中取得了良好的效果。在少数情况下,残余的膀胱膨出可能是一个麻烦或问题。
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引用次数: 0
[Aortoiliac surgery in chronic hemodialysed patients]. [慢性血液透析患者的主动脉髂手术]。
M Lacombe

Thirty eight patients on chronic hemodialysis were operated on for treatment of complicated aortoiliac atherosclerosis: 31 had aneurysms and 7 had stenotic or obstructive lesions. The 35 male and three female patients ranged in age from 39 to 78 years (mean: 55.3). The duration of hemodialysis treatment before the operation ranged from one month to 22 years but 80% of the patients were operated on during the first five years following the beginning of maintenance hemodialysis. The surgical repairs consisted of long aorta to femoral artery prosthesis in obstructive lesions and of short prostheses in cases of aneurysms so as not to make more difficult subsequent renal transplantation. All patients were operated on from 6 to 18 hours after a dialysis. Hemodialysis was resumed on the day of surgery in few patients or later according to the level of kalemia. Postoperative mortality rate was 10.5% and morbidity 13.5%. Only seven patients underwent secondary renal transplantation. The long-term survival rate was 43% at five years and 11% at ten years. Late deaths were due to coronary artery disease or to worsening of arterial lesions in the lower limbs.

对38例慢性血液透析治疗并发主动脉髂动脉粥样硬化患者进行手术治疗,其中动脉瘤31例,狭窄或梗阻性病变7例。男35例,女3例,年龄39 ~ 78岁,平均55.3岁。术前血液透析治疗时间从1个月到22年不等,但80%的患者在开始维持性血液透析后的前5年内进行了手术。手术修复包括梗阻性病变的长主动脉至股动脉假体和动脉瘤的短假体,以避免给后续肾移植带来困难。所有患者在透析后6至18小时进行手术。少数患者根据血钾水平在手术当日或之后恢复血液透析。术后死亡率10.5%,发病率13.5%。只有7例患者接受了继发性肾移植。5年和10年的长期生存率分别为43%和11%。晚期死亡是由于冠状动脉疾病或下肢动脉病变恶化。
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引用次数: 0
[Reoperations of total hip prosthesis with acetabular reconstruction using bone allografts]. 全髋关节假体髋臼骨异体移植再手术研究。
L E Gayet, F Morand, J P Clarac, P Pries, P Babin

Detachment of the acetabular segment is the most important long-term problem with total hip prostheses. We analyzed long-term outcome in our first 48 acetabular reconstructions with cryopreserved allografts. Among the 48 hips operated on with this technique, 38 were reassessed after a mean follow-up of 7 years 3 months (range 5 years-9 years 6 months). Mean age of the population at surgery was 63 years. There were two predominant etiologies: sequelae of chronic hip luxation and primary osteoarthrosis of the hip. In 10 cases with massive destruction, the Müller ring was used to stabilize the allograft. Results were assessed at 6 months, 2 years, 4 years and at longest follow-up using the Merle d'Aubigné clinical assessment scale. For the radiographic assessment, the Ranawat criteria were used to evaluate the alignment of the reconstruction. Clinically, patient comfort was improved in all cases with significant pain relief. Radiologically, mean acetabular ascention was 5 mm and mean medialization was 3.5 mm. A rim was observed in 24 cases including 19 measuring less than 2 cm. Acetabular loosening was evidenced in the 5 other cases where the rim measured more than 2 mm. In 4 of these 5 cases, the acetabulum had migrated to a new setting. The radiographic image then remained unchanged. Analysis of our 38 first cases showed that bone allografts with cimented acetabulum, sometimes with a stabilizing ring, is one of the possible solutions for difficult acetabular reconstructions. However, after a 7 years 3 months follow-up, we have had five (13%) aseptic displacements including one case requiring reoperation. In the 33 stable joints (87%) with good results reconstruction has achieved a nearly perfect anatomic position, similar to first intention arthroplasty with the use of perfectly stabilized bone grafts with a maximal acetabular surface. Our follow-up is longer than most published in the literature. However, the migration rate of 13% it is still too short to draw any conclusion concerning the long-term outcome in our patients, despite their older age and reduced physical activity compared with primary hip arthroplasty patients.

髋臼段脱离是全髋关节置换术中最重要的长期问题。我们分析了前48例低温保存同种异体髋臼重建的长期结果。在采用该技术手术的48例髋关节中,38例在平均随访7年3个月(5年-9年6个月)后重新评估。手术人群的平均年龄为63岁。有两种主要的病因:慢性髋关节脱位的后遗症和原发性髋关节骨关节病。在10例大面积破坏的病例中,使用m ller环来稳定同种异体移植物。在随访6个月、2年、4年和最长随访时间时,采用Merle d’aubign临床评估量表对结果进行评估。放射学评估使用Ranawat标准评估重建的对齐。在临床上,所有病例的患者舒适度均得到改善,疼痛明显缓解。放射学上,髋臼平均上升5毫米,平均中间化3.5毫米。24例观察到边缘,其中19例测量小于2厘米。髋臼松动在另外5例髋臼边缘大于2mm的病例中得到证实。5例中有4例髋臼移位到新的位置。然后放射图像保持不变。我们对38例首次病例的分析表明,骨同种异体移植物带椎体臼,有时带稳定环,是困难的髋臼重建的可能解决方案之一。然而,经过7年3个月的随访,我们有5例(13%)无菌移位,其中1例需要再次手术。在33个稳定关节(87%)中,重建获得了近乎完美的解剖位置,类似于首次关节置换术,使用了具有最大髋臼表面的完全稳定的骨移植物。我们的后续研究比大多数发表的文献都要长。然而,13%的迁移率仍然太短,无法得出关于我们患者长期结果的任何结论,尽管与原发性髋关节置换术患者相比,他们的年龄更大,体力活动减少。
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引用次数: 0
[Diagnosis of adenopathies and retroperitoneal masses by surgical endoscopy. Apropos of 93 cases]. 手术内镜对腺病和腹膜后肿物的诊断。[约93例]。
H Porte, A Wurtz, L Gambiez, S Jaillard Thery, J P Chambon, F Bauters, B Gosselin

Lumboscopy is an endoscopic surgical technique providing direct visualization of the retroperitoneal space from the kidney hilium to the iliac bifurcation. We report our 10-year experience with this technique used to diagnose masses in the retroperitoneal space. This method is not very invasive and the morbidity is low. The sensitivity is greater than needle biopsy under CT guidance.

腰镜检查是一种内窥镜手术技术,提供从肾门到髂分叉的腹膜后空间的直接可视化。我们报告了我们10年来使用这种技术诊断腹膜后间隙肿块的经验。该方法侵入性小,发病率低。敏感性大于CT引导下的穿刺活检。
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引用次数: 0
[Antibiotic release by tricalcic phosphate bone implantation. In vitro and in vivo pharmacokinetics of different galenic forms]. 磷酸三钙骨植入的抗生素释放。不同galenic形式的体内外药代动力学研究[j]。
H Thomazeau, F Langlais

The purpose of this study was to evaluate the load and the release of antibiotics obtained with an implant made of a macroporous beta tricalcium phosphate ceramic (beta-TCP). Two parameters have been assessed: macroporosity and external shape (beads and parallelepipeds). In vitro, the ceramic beads were soaked in a Vancomycin-aqueous-solution, and the load of the antibiotic was then evaluated: it was 9.3% of the weight of the 40%-porosity beads and 4.6% of the weight of the 20%-porosity beads. The release has been evaluated by elution in phosphate-buffered-saline (PBS). With a 20% porosity, 12 beads (6.3 mm, 279 +/- 38 mg) demonstrated a short an massive release which ended within the 32 first hours. On the opposite, the release was sustained until the third week for the 40%-porosity beads (6.9 mm, 353 +/- 25 mg), while only one third of the load was released during the first 24 hours. A macroporosity of 40% of the ceramic could allow a deep incorporation of the antibiotic in the beads and thus decrease the rate of release. The in vivo study compared the bone concentrations of antibiotics obtained after implantations of either parallelepipedical or spherical devices in the distal femurs of 14 sheep. The bone concentrations of Gentamicin obtained with parallelepipeds until the end of the third week were from 5 to 10 times the minimum inhibitory concentration of this antibiotic for staphylococci. On the opposite, beads achieved only low concentrations of Vancomycin and nearly no detectable Gentamicin in the bone. We hypothesize a negative effect of the fibrous tissue which fills the gaps between the beads, and which could impair the diffusion of the antibiotics into the bone.

本研究的目的是评估由大孔β -磷酸三钙陶瓷(β - tcp)制成的种植体所获得的抗生素的负荷和释放。评估了两个参数:宏观孔隙度和外部形状(珠状和平行六面体)。在体外,将陶瓷珠浸泡在万古霉素水溶液中,然后评估抗生素的负荷:它是40%孔隙率珠重量的9.3%和20%孔隙率珠重量的4.6%。通过磷酸盐缓冲盐水(PBS)洗脱来评估释放。在孔隙率为20%的情况下,12个微珠(6.3 mm, 279 +/- 38 mg)在第一个32小时内短暂而大量释放。相反,40%孔隙率珠(6.9 mm, 353 +/- 25 mg)的释放持续到第三周,而在前24小时内只有三分之一的负载被释放。陶瓷的大孔隙率为40%,可以使抗生素在微珠中深度结合,从而降低释放速度。体内研究比较了在14只羊的远端股骨中植入平行六面体或球形装置后获得的抗生素骨浓度。直到第三周结束时,平行六面体获得的庆大霉素骨浓度为该抗生素对葡萄球菌最低抑制浓度的5至10倍。相反,小珠子只能在骨头中检测到低浓度的万古霉素,几乎没有检测到庆大霉素。我们假设纤维组织的负面影响,它填补了珠子之间的空隙,这可能会损害抗生素在骨骼中的扩散。
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引用次数: 0
[Value of cutaneous allografts in the treatment of severe burns]. [同种异体皮肤移植在严重烧伤治疗中的价值]。
M Schlotterer

Skin allografts are essential for survival in patients who have suffered major third degree burns over more than 50% of the body surface in order to maintain covering until autografts from less severely wounded areas can be performed or until keratinocyte cultures have grown. Allografts have thus been increasingly used for severe burn patients. It has been estimated that 150 m2 are grafted per year in France. Both fresh and frozen tissue can be used thanks to the organization of graft banks and safe storage.

同种异体皮肤移植对于体表超过50%的严重三度烧伤患者的生存是必不可少的,以便保持覆盖,直到可以从较轻的损伤区域进行自体移植或直到角质细胞培养生长。因此,同种异体移植越来越多地用于严重烧伤患者。据估计,法国每年嫁接150平方米。由于移植物库的组织和安全的储存,新鲜和冷冻组织都可以使用。
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引用次数: 0
[Spinal cord astrocytomas and ependymomas: therapeutic strategy]. 脊髓星形细胞瘤和室管膜瘤:治疗策略。
G Fischer

Ependymomas and astrocytomas are the most frequent spinal cord tumors. They have the same clinical expression and the only treatment is surgery. We report the experience of two neurochurgical teams working in Lyon and Brussels with 171 operated patients, focusing on therapeutic strategies. Spinal cord ependymomas usually present as circumscribed benin tumors, complete exeresis is the best strategy. Long-term follow-up in 40 patients who were not given adjuvant radiotherapy showed no recurrence and satisfactory functional results. Astrocytomas are classically less well circumscribed but when exeresis is macroscopically complete, results are comparable with those of ependymomas as was found in 22 patients with long-term follow-up. Inversely, for infiltrating astrocytomas, pathology is usually malignant and prognosis is unfavorable despite radiotherapy or chemotherapy.

室管膜瘤和星形细胞瘤是最常见的脊髓肿瘤。它们具有相同的临床表现,唯一的治疗方法是手术。我们报告了两个神经外科团队在里昂和布鲁塞尔工作的171例手术患者的经验,重点是治疗策略。脊髓室管膜瘤通常表现为局限的贝宁肿瘤,完全运动是最好的策略。未给予辅助放疗的40例患者,长期随访无复发,功能效果满意。星形细胞瘤通常界限不明确,但当运动在宏观上完成时,结果与22例长期随访的室管膜瘤相当。相反,浸润性星形细胞瘤的病理通常是恶性的,无论放疗或化疗,预后都不好。
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引用次数: 0
[Evaluating the efficacy of a multidisciplinary approach of severe functional deficits]. [评估多学科方法治疗严重功能缺陷的疗效]。
F Lapierre, L E Gayet, C Delaubier, G Duport, J M Servant

Therapeutic indications aimed at improving function in handicapped persons are difficult to establish as the expected result of a given technique may vary. We have developed a multidisiplinary approach for handicapped persons. Our assessment of this activity which has concerned 62 patients from October 1995 to October 1996 is promising and encourages us to continue this type of attitude. Forty-six of the 58 persons evaluated stated they were well satisfied or very well satisfied with the management of their case and outcome was worse in none of the patients.

旨在改善残疾人功能的治疗指征很难确定,因为给定技术的预期结果可能会有所不同。我们为残疾人制定了一个多学科的方法。我们对1995年10月至1996年10月期间涉及62名病人的这项活动的评估是有希望的,并鼓励我们继续采取这种态度。在接受评估的58人中,有46人表示他们对自己的病例管理感到满意或非常满意,没有一个患者的结果更差。
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引用次数: 0
期刊
Chirurgie; memoires de l'Academie de chirurgie
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