Ni Putu Omasih Kiantimi, Komang Sarizki Armidita, I Nyoman Satria Pratama, Made Rara Rusmala Dewi M, A.A Sagung Dewi Nurgitayanti
Background: It is not entirely apparent how chronic rhinosinusitis (also known as CRS) develops. Since the 1970s, medical professionals have debated whether or not gastroesophageal reflux (GOR) could be a factor in the development of certain patients' conditions. The purpose of this research is to the relation between chronic rhinosinusitis and gastroesophageal reflux in adults. Methods: By evaluating the preferred reporting items for systematic review and meta-analysis (PRISMA) 2020 standards, this study demonstrated that it met all of the requirements. This enabled the researchers to ensure that the study was as up to date as feasible. Publications published between 2000 and 2023 were included in the search strategy, which included a variety of electronic reference databases (including Pubmed and SagePub). We did not consider review papers, duplicate publications, or half completed articles. Results: In the PubMed database, the results of our search brought up 133 articles, whereas the results of our search on SagePub brought up 69 articles. The results of the search conducted for the last year of 2000 yielded a total of 20 articles for PubMed and 8 articles for SagePub. In the end, we compiled a total of 21 papers, six of which came from PubMed and three of which came from SagePub. We included nine research that met the criteria. Conclusion: According to the findings of most studies, the number of cases of CRS seen in patients with GERD is around two to three times higher than that seen in the general patient group.
{"title":"Relation between Chronic Rhinosinusitis and Gastroesophageal Reflux in Adults: A Systematic Review","authors":"Ni Putu Omasih Kiantimi, Komang Sarizki Armidita, I Nyoman Satria Pratama, Made Rara Rusmala Dewi M, A.A Sagung Dewi Nurgitayanti","doi":"10.37275/bsm.v7i9.860","DOIUrl":"https://doi.org/10.37275/bsm.v7i9.860","url":null,"abstract":"Background: It is not entirely apparent how chronic rhinosinusitis (also known as CRS) develops. Since the 1970s, medical professionals have debated whether or not gastroesophageal reflux (GOR) could be a factor in the development of certain patients' conditions. The purpose of this research is to the relation between chronic rhinosinusitis and gastroesophageal reflux in adults. \u0000Methods: By evaluating the preferred reporting items for systematic review and meta-analysis (PRISMA) 2020 standards, this study demonstrated that it met all of the requirements. This enabled the researchers to ensure that the study was as up to date as feasible. Publications published between 2000 and 2023 were included in the search strategy, which included a variety of electronic reference databases (including Pubmed and SagePub). We did not consider review papers, duplicate publications, or half completed articles. \u0000Results: In the PubMed database, the results of our search brought up 133 articles, whereas the results of our search on SagePub brought up 69 articles. The results of the search conducted for the last year of 2000 yielded a total of 20 articles for PubMed and 8 articles for SagePub. In the end, we compiled a total of 21 papers, six of which came from PubMed and three of which came from SagePub. We included nine research that met the criteria. \u0000Conclusion: According to the findings of most studies, the number of cases of CRS seen in patients with GERD is around two to three times higher than that seen in the general patient group.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130844553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monocyte chemoattractant protein-1 plays an important role in kidney disease. In several studies, the role of MCP-1 as a urine biomarker has been extensively studied. In many kidney diseases, there are elevated levels of MCP-1 in the kidney tissue and this is an important cause of monocyte infiltration in the pathogenesis of kidney damage. Elevated urinary MCP-1 levels have been able to predict outcome in proliferative kidney diseases such as lupus nephritis. However, in several studies it was also found that there was an increase in MCP-1 in diabetic kidney disease. Macrophages have even appeared early in diabetic kidney disease and are associated with the progression of kidney disease. Urinary MCP-1 levels are related to the degree of leukocyte infiltration in the tubulointerstitial. This supports inflammatory factors as part of the pathogenesis of diabetic kidney disease.
{"title":"The Role of Monocyte Chemoattractant Protein-1 (MCP-1) in Diabetic Kidney Disease","authors":"Deddy Canceria, Suka Rahmatsyah, Harnavi Harun, Deka Viotra","doi":"10.37275/bsm.v7i9.861","DOIUrl":"https://doi.org/10.37275/bsm.v7i9.861","url":null,"abstract":"Monocyte chemoattractant protein-1 plays an important role in kidney disease. In several studies, the role of MCP-1 as a urine biomarker has been extensively studied. In many kidney diseases, there are elevated levels of MCP-1 in the kidney tissue and this is an important cause of monocyte infiltration in the pathogenesis of kidney damage. Elevated urinary MCP-1 levels have been able to predict outcome in proliferative kidney diseases such as lupus nephritis. However, in several studies it was also found that there was an increase in MCP-1 in diabetic kidney disease. Macrophages have even appeared early in diabetic kidney disease and are associated with the progression of kidney disease. Urinary MCP-1 levels are related to the degree of leukocyte infiltration in the tubulointerstitial. This supports inflammatory factors as part of the pathogenesis of diabetic kidney disease.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"341 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127576253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Essential thrombocythemia (ET) is a rare disease in which there is an increase in the platelet count of more than 450,000/mm3. An increase in the number of platelets occurs due to increased proliferation of megakaryocyte series. Although there is an increase in the number of platelets in ET, it has impaired function. ET clinical manifestations in 50% of cases are asymptomatic, but in symptomatic cases can be vascular occlusive events or microvascular thrombosis. Case presentation: A 22-year-old woman with complaints of rash on the hands and feet. Physical examination found an enlarged spleen in Schuffner 1 and ecchymosis on the arms and legs, a platelet count of 811,000/mm3. The peripheral blood smear shows large platelets, the bone marrow picture shows megakaryocytes, which are very easy to find, the size varies with sufficient platelet emission, the JAK2 gene mutation examination shows mutation detection, while the BCR-ABL gene mutation results do not detect gene fusion. Treatment is given cytoreductive therapy in the form of hydroxyurea, while acetylsalicylic acid is not given because there are contraindications for administration. Conclusion: Essential thrombocythemia is a neoplastic proliferative disease that occurs in the megakaryocyte series. The diagnosis of ET mostly found mutations in the JAK2 gene. ET management according to risk classification, where acetylsalicylic acid can be given very low and low risk, while intermediate and high risk can be given cytoreductive therapy.
{"title":"Essential Thrombocythemia in Young Women","authors":"Anggit Pungkas Wibowo, Eifel Faheri, Anggit Pungkas","doi":"10.37275/bsm.v7i9.857","DOIUrl":"https://doi.org/10.37275/bsm.v7i9.857","url":null,"abstract":"Background: Essential thrombocythemia (ET) is a rare disease in which there is an increase in the platelet count of more than 450,000/mm3. An increase in the number of platelets occurs due to increased proliferation of megakaryocyte series. Although there is an increase in the number of platelets in ET, it has impaired function. ET clinical manifestations in 50% of cases are asymptomatic, but in symptomatic cases can be vascular occlusive events or microvascular thrombosis. \u0000Case presentation: A 22-year-old woman with complaints of rash on the hands and feet. Physical examination found an enlarged spleen in Schuffner 1 and ecchymosis on the arms and legs, a platelet count of 811,000/mm3. The peripheral blood smear shows large platelets, the bone marrow picture shows megakaryocytes, which are very easy to find, the size varies with sufficient platelet emission, the JAK2 gene mutation examination shows mutation detection, while the BCR-ABL gene mutation results do not detect gene fusion. Treatment is given cytoreductive therapy in the form of hydroxyurea, while acetylsalicylic acid is not given because there are contraindications for administration. \u0000Conclusion: Essential thrombocythemia is a neoplastic proliferative disease that occurs in the megakaryocyte series. The diagnosis of ET mostly found mutations in the JAK2 gene. ET management according to risk classification, where acetylsalicylic acid can be given very low and low risk, while intermediate and high risk can be given cytoreductive therapy.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"49 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114001029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: One of the risk factors that can increase the incidence of anemia in pregnant women is the close spacing of pregnancies and multiparity. Closely spaced pregnancies refer to pregnancies that occur within a short time after the previous birth, while multiparity refers to a woman who has given birth to more than one child previously. The combination of these two factors can lead to an increased risk of anemia in pregnant women. This study presents the risk of closely spaced pregnancies and multiparity for the incidence of anemia in pregnant women. Case presentation: Mrs. SM, 27 years old pregnant woman, came with complaints of severe dizziness for the last 2 weeks. In addition, patients also complain of weakness, weakness, no energy, and no appetite. The patient said that she was currently pregnant with her 4th child, aged 27-28 weeks, with active fetal movements. Hemoglobin examination 7 mg/dL. Conclusion: The patient was diagnosed with anemia in pregnant women with risk factors for close pregnancy spacing and multiparity.
{"title":"Incidence of Anemia in Pregnant Women with Closer Spacing of Pregnancies and Multiparity: A Case Report","authors":"L. Amalina","doi":"10.37275/bsm.v7i9.858","DOIUrl":"https://doi.org/10.37275/bsm.v7i9.858","url":null,"abstract":"Background: One of the risk factors that can increase the incidence of anemia in pregnant women is the close spacing of pregnancies and multiparity. Closely spaced pregnancies refer to pregnancies that occur within a short time after the previous birth, while multiparity refers to a woman who has given birth to more than one child previously. The combination of these two factors can lead to an increased risk of anemia in pregnant women. This study presents the risk of closely spaced pregnancies and multiparity for the incidence of anemia in pregnant women. Case presentation: Mrs. SM, 27 years old pregnant woman, came with complaints of severe dizziness for the last 2 weeks. In addition, patients also complain of weakness, weakness, no energy, and no appetite. The patient said that she was currently pregnant with her 4th child, aged 27-28 weeks, with active fetal movements. Hemoglobin examination 7 mg/dL. Conclusion: The patient was diagnosed with anemia in pregnant women with risk factors for close pregnancy spacing and multiparity.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"-1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132777240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pathophysiology of primary osteoporosis primarily involves changes at the cellular and bone tissue levels. This process involves an imbalance between the activity of bone-destroying cells (osteoclasts) and bone-constructing cells (osteoblasts). Osteoclasts are responsible for the resorption of old and damaged bone tissue, while osteoblasts build new bone. In osteoporosis, osteoclast activity increases and osteoblasts decrease, resulting in loss of bone mass. Treatment of primary osteoporosis involves a holistic approach that includes lifestyle changes, use of medications, and fracture prevention. The main goal of management is to slow down the decline in bone density, prevent bone fractures, and improve the quality of life of sufferers. Increasing your intake of calcium and vitamin D, as well as regular physical exercise, can help maintain bone mass. Meanwhile, drugs such as bisphosphonates and teriparatide can be used to inhibit bone breakdown or stimulate new bone formation.
{"title":"Pathophysiology and Management of Primary Osteoporosis: A Narrative Literature Review","authors":"Dendi Andrean, Najirman, Eka Kurniawan","doi":"10.37275/bsm.v7i8.856","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.856","url":null,"abstract":"The pathophysiology of primary osteoporosis primarily involves changes at the cellular and bone tissue levels. This process involves an imbalance between the activity of bone-destroying cells (osteoclasts) and bone-constructing cells (osteoblasts). Osteoclasts are responsible for the resorption of old and damaged bone tissue, while osteoblasts build new bone. In osteoporosis, osteoclast activity increases and osteoblasts decrease, resulting in loss of bone mass. Treatment of primary osteoporosis involves a holistic approach that includes lifestyle changes, use of medications, and fracture prevention. The main goal of management is to slow down the decline in bone density, prevent bone fractures, and improve the quality of life of sufferers. Increasing your intake of calcium and vitamin D, as well as regular physical exercise, can help maintain bone mass. Meanwhile, drugs such as bisphosphonates and teriparatide can be used to inhibit bone breakdown or stimulate new bone formation.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116578088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The prevalence of preeclampsia is around 5% - 15% of all pregnant women. It can cause severe complications and even death in the mother and fetus if not adequately managed. Case presentation: A 36-year-old housewife was admitted to the emergency department with a chief complaint of shortness of breath before hospital arrival. The patient also complained of headaches. From the physical examination, consciousness was compos mentis, blood pressure 162/100 mmHg, HR 90 x/min, RR 24x/min, SpO 96%. From abdominal ultrasound gravid 36-37 weeks according to biometry, fetal alive, gemelli, intrauterine, transverse lie right head dorsoinferior- breech presentation, the Laboratory in emergency room result, haemoglobin: 10,4, leukocyte, 13.020, thrombocyte 359.000, hematocrit 31, ureum: 11, creatinin: 0.5, glucose: 72, protein urine: +2. Conclusion: In patients with preeclampsia, proper diagnosis and appropriate treatment in the intensive care unit and management by a multidisciplinary team can prevent preeclampsia complications and improve preeclamptic patients' outcomes.
{"title":"Intensive Care Management of Preeclampsia: A Case Report","authors":"Liliriawati Ananta, Kahar, Wiwi Monika Sari, Mentari Faisal Putri","doi":"10.37275/bsm.v7i8.853","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.853","url":null,"abstract":"Background: The prevalence of preeclampsia is around 5% - 15% of all pregnant women. It can cause severe complications and even death in the mother and fetus if not adequately managed. \u0000Case presentation: A 36-year-old housewife was admitted to the emergency department with a chief complaint of shortness of breath before hospital arrival. The patient also complained of headaches. From the physical examination, consciousness was compos mentis, blood pressure 162/100 mmHg, HR 90 x/min, RR 24x/min, SpO 96%. From abdominal ultrasound gravid 36-37 weeks according to biometry, fetal alive, gemelli, intrauterine, transverse lie right head dorsoinferior- breech presentation, the Laboratory in emergency room result, haemoglobin: 10,4, leukocyte, 13.020, thrombocyte 359.000, hematocrit 31, ureum: 11, creatinin: 0.5, glucose: 72, protein urine: +2. \u0000Conclusion: In patients with preeclampsia, proper diagnosis and appropriate treatment in the intensive care unit and management by a multidisciplinary team can prevent preeclampsia complications and improve preeclamptic patients' outcomes.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"397 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126756847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitiligo is a depigmentation disorder that is commonly found in the community. The causes of vitiligo are multifactorial such as genetic and environmental factors accompanied by the presence of non-specific and specific immune system factors. Melanocytes are the main target exposed by reactive oxygen species (ROS) during the process of melanogenesis. Such exposure can cause loss of homeostasis and cell death and has implications for vitiligo. Clinical manifestations of vitiligo are generally white depigmented macular lesions that are well demarcated. Based on its distribution, vitiligo can be divided into segmental and non-segmental vitiligo different in terms of prognosis, treatment and resolution of vitiligo.
{"title":"The Effect of Free Radicals on Vitiligo","authors":"Pristia Widya, N. Mulianto","doi":"10.37275/bsm.v7i8.855","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.855","url":null,"abstract":"Vitiligo is a depigmentation disorder that is commonly found in the community. The causes of vitiligo are multifactorial such as genetic and environmental factors accompanied by the presence of non-specific and specific immune system factors. Melanocytes are the main target exposed by reactive oxygen species (ROS) during the process of melanogenesis. Such exposure can cause loss of homeostasis and cell death and has implications for vitiligo. Clinical manifestations of vitiligo are generally white depigmented macular lesions that are well demarcated. Based on its distribution, vitiligo can be divided into segmental and non-segmental vitiligo different in terms of prognosis, treatment and resolution of vitiligo.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115963537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maya Sofa, M. P. Soemitro, M. Abdurahman, Y. Azhar, Kiki A. Rizky
Background: Sarcoma is a malignant neoplasm originating from mesodermal tissue with an incidence rate of 1% of neoplasms throughout the body. Head and neck sarcoma requires more complex management and until now, reviews of this disease are still very rare. This study aimed to report the incidence and characteristics of head and neck sarcoma during 2017-2021 at Dr. Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung. Methods: Research data was taken from patient medical records through SIRS at Dr. Hasan Sadikin General Hospital during the 2017-2021 period according to the ICD10 of head and neck malignancies and histopathological data. Results: During 2017-2021, 15 cases of head and neck sarcoma were found, consisting of 9 cases (60%) rhabdomyosarcoma, 2 cases (13.3%) fibrosarcoma, and 1 case each (6.7%) synovial sarcoma, undifferentiated pleomorphic sarcoma, angiosarcoma and dermatofibrosarcoma protuberans. The neck and shoulder area are the most frequently affected site (40%), followed by the scalp (26.7%), maxilla (20%), and oral cavity (13.3%). The highest incidence rates were in female (60%) and children aged <17 years (46.7%). Conclusion: The incidence of head and neck sarcoma at Dr. Hasan Sadikin General Hospital Bandung is rare. The most frequent cases are rhabdomyosarcoma the most commonly affected areas are the neck and shoulders.
背景:肉瘤是一种起源于中胚层组织的恶性肿瘤，发病率为全身肿瘤的1%。头颈部肉瘤需要更复杂的治疗，直到现在，对这种疾病的评论仍然非常罕见。本研究旨在报告2017-2021年万隆Padjadjaran大学Hasan Sadikin医生总医院头颈部肉瘤的发病率和特征。方法:根据头颈部恶性肿瘤ICD10和组织病理学数据，通过SIRS从Dr. Hasan Sadikin总医院2017-2021年期间的患者病历中获取研究数据。结果:2017-2021年共发现头颈部肉瘤15例，其中横纹肌肉瘤9例(60%)，纤维肉瘤2例(13.3%)，滑膜肉瘤、未分化多形性肉瘤、血管肉瘤、隆突性皮肤纤维肉瘤各1例(6.7%)。颈部和肩部是最常见的受累部位(40%)，其次是头皮(26.7%)、上颌骨(20%)和口腔(13.3%)。发病率最高的是女性(60%)和<17岁的儿童(46.7%)。结论:万隆哈桑·萨迪金总医院头颈部肉瘤发病率低。最常见的病例是横纹肌肉瘤，最常见的受累部位是颈部和肩部。
{"title":"Head and Neck Sarcomas Characteristics at Dr. Hasan Sadikin General Hospital for 5 Years (2017-2021)","authors":"Maya Sofa, M. P. Soemitro, M. Abdurahman, Y. Azhar, Kiki A. Rizky","doi":"10.37275/bsm.v7i8.854","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.854","url":null,"abstract":"Background: Sarcoma is a malignant neoplasm originating from mesodermal tissue with an incidence rate of 1% of neoplasms throughout the body. Head and neck sarcoma requires more complex management and until now, reviews of this disease are still very rare. This study aimed to report the incidence and characteristics of head and neck sarcoma during 2017-2021 at Dr. Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung. \u0000Methods: Research data was taken from patient medical records through SIRS at Dr. Hasan Sadikin General Hospital during the 2017-2021 period according to the ICD10 of head and neck malignancies and histopathological data. \u0000Results: During 2017-2021, 15 cases of head and neck sarcoma were found, consisting of 9 cases (60%) rhabdomyosarcoma, 2 cases (13.3%) fibrosarcoma, and 1 case each (6.7%) synovial sarcoma, undifferentiated pleomorphic sarcoma, angiosarcoma and dermatofibrosarcoma protuberans. The neck and shoulder area are the most frequently affected site (40%), followed by the scalp (26.7%), maxilla (20%), and oral cavity (13.3%). The highest incidence rates were in female (60%) and children aged <17 years (46.7%). \u0000Conclusion: The incidence of head and neck sarcoma at Dr. Hasan Sadikin General Hospital Bandung is rare. The most frequent cases are rhabdomyosarcoma the most commonly affected areas are the neck and shoulders.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131150710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Refractive error is the first cause of visual impairment and the second cause of vision loss worldwide. Astigmatism is an eye refraction disorder that is characterized by various degrees of refraction in various meridians. Thus, the parallel rays coming into the eye are not focused on one point. One of the treatments is toric soft contact lenses, which is used in astigmatism patients by 47% with astigmatism above 0.75 D. This case report describes the use of toric soft contact lenses using a trial with markers at 6 o'clock, 3 o'clock, and 9 o'clock for the management of regular astigmatism. Case presentation: In this paper, we report 3 cases of patients using toric soft contact lenses. The first patient was a 29-year-old male, the second patient was a 24-year-old female, and the third patient was a 25-year-old male with slowly blurred vision in both eyes and had been wearing glasses. The three cases were classified as moderate astigmatism with a power of 1.25 D and 1.50 D. The patients were given toric soft contact lenses for correction. Contact lens fitting was performed on the patient. Conclusion: Correction of astigmatism can be done by giving glasses, contact lenses, or refractive surgery. If the contact lens axis is suitable, a prescription can be given immediately. If the axis of the toric soft contact lens does not match the available trials, it is necessary to order the size of the toric contact lens according to the astigmatism disorder in the patient's eye.
{"title":"How to Fit Toric Soft Contact Lenses?","authors":"Astria Rima, Rara Yuswir, Rinda Wati","doi":"10.37275/bsm.v7i8.851","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.851","url":null,"abstract":"Background: Refractive error is the first cause of visual impairment and the second cause of vision loss worldwide. Astigmatism is an eye refraction disorder that is characterized by various degrees of refraction in various meridians. Thus, the parallel rays coming into the eye are not focused on one point. One of the treatments is toric soft contact lenses, which is used in astigmatism patients by 47% with astigmatism above 0.75 D. This case report describes the use of toric soft contact lenses using a trial with markers at 6 o'clock, 3 o'clock, and 9 o'clock for the management of regular astigmatism. \u0000Case presentation: In this paper, we report 3 cases of patients using toric soft contact lenses. The first patient was a 29-year-old male, the second patient was a 24-year-old female, and the third patient was a 25-year-old male with slowly blurred vision in both eyes and had been wearing glasses. The three cases were classified as moderate astigmatism with a power of 1.25 D and 1.50 D. The patients were given toric soft contact lenses for correction. Contact lens fitting was performed on the patient. \u0000Conclusion: Correction of astigmatism can be done by giving glasses, contact lenses, or refractive surgery. If the contact lens axis is suitable, a prescription can be given immediately. If the axis of the toric soft contact lens does not match the available trials, it is necessary to order the size of the toric contact lens according to the astigmatism disorder in the patient's eye.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"218 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123090765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: BRVO is a blockage of the branches of the retinal vein due to a thrombus. The prevalence of 10-year BRVO is 1.6 per 100 subjects. The effect of anti-VEGF injection on BRVO management is effective in improving visual acuity and reducing macular oedema. Case presentation: A man, 32 years old, presented to the ophthalmology clinic at the Dr. M. Djamil General Hospital with a chief complaint of blurred vision in his left eye 1 week before admission. The blurred vision began suddenly. Visual acuity in LE was 20/50 and did not advance with a pinhole. Funduscopic examination of LE showed clear media, rounded papillae with well-defined borders, blood vessels aa:vv = 1:3, venous tortuosity (+) increased in the inferotemporal quadrant; retina: Bleeding (+) with dot blot and flame-shaped inferiorly, exudate (+) cotton wool spots at the inferotemporal region; foveal reflex (+)↓ on the macula. OCT LE examination showed macular intraretinal hypo-reflection and macular thickening with a central macular thickness of 617 μm. The physical examination showed a body weight of 114.9 kg, a height of 173 cm, and a body mass index of 38.4. Within 5 months after 3 times administrations of intravitreal injections of anti-VEGF bevacizumab and ranibizumab, visual acuity of LE: 20/25 was obtained, and increased appearance of the retinal fundus and OCT LE. Conclusion: Intravitreal injection therapy of anti-VEGF bevacizumab and ranibizumab is effective in reducing macular oedema and restoring visual acuity in BRVO.
{"title":"Comparing the Optical Coherence Tomography Outcomes of Intravitreal Injection Anti Vascular Endothelial Growth Factor in Branch Retinal Vein Occlusion (BRVO)","authors":"Sandri, Weni Helvinda","doi":"10.37275/bsm.v7i8.852","DOIUrl":"https://doi.org/10.37275/bsm.v7i8.852","url":null,"abstract":"Background: BRVO is a blockage of the branches of the retinal vein due to a thrombus. The prevalence of 10-year BRVO is 1.6 per 100 subjects. The effect of anti-VEGF injection on BRVO management is effective in improving visual acuity and reducing macular oedema. \u0000Case presentation: A man, 32 years old, presented to the ophthalmology clinic at the Dr. M. Djamil General Hospital with a chief complaint of blurred vision in his left eye 1 week before admission. The blurred vision began suddenly. Visual acuity in LE was 20/50 and did not advance with a pinhole. Funduscopic examination of LE showed clear media, rounded papillae with well-defined borders, blood vessels aa:vv = 1:3, venous tortuosity (+) increased in the inferotemporal quadrant; retina: Bleeding (+) with dot blot and flame-shaped inferiorly, exudate (+) cotton wool spots at the inferotemporal region; foveal reflex (+)↓ on the macula. OCT LE examination showed macular intraretinal hypo-reflection and macular thickening with a central macular thickness of 617 μm. The physical examination showed a body weight of 114.9 kg, a height of 173 cm, and a body mass index of 38.4. Within 5 months after 3 times administrations of intravitreal injections of anti-VEGF bevacizumab and ranibizumab, visual acuity of LE: 20/25 was obtained, and increased appearance of the retinal fundus and OCT LE. \u0000Conclusion: Intravitreal injection therapy of anti-VEGF bevacizumab and ranibizumab is effective in reducing macular oedema and restoring visual acuity in BRVO.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130813933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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