Clinical Case Reports最新文献

Extra-nasopharyngeal angiofibroma is a rare entity, with only a few cases reported to date. It usually presents with symptoms resembling those of typical nasopharyngeal angiofibroma, but it arises from a site other than the site of origin of typical nasopharyngeal angiofibroma. A 20-year-old male presented with complaints of left-sided nasal obstruction and epistaxis for 10 days. On examination, a mass was seen attached to the anterior nasal septum. Throat and ear examinations were unremarkable. Blood investigations also came out to be as expected. A deviated nasal septum was seen, which was caused by a nasal trauma to this patient 3 years ago. This mass was removed, and the specimen was sent for histologic examination. Histologic examination of the specimen proved the mass to be extra-nasopharyngeal angiofibroma. The selection of appropriate surgical techniques and subsequent histologic examinations is extremely important to determine the exact diagnosis in such cases. The case addressed in this case report is extremely important for uncovering another rare case of extra-nasopharyngeal angiofibroma. This case might also suggest a possible linkage between extra-nasopharyngeal angiofibroma and a deviated nasal septum.

Root perforation may happen pathologically or iatrogenically at any stage of endodontic treatment. Repairing a Perforation can be challenging and can negatively affect the prognosis of the treatment. The prognosis depends on various factors, including the size and site of the perforation, the presence of microorganisms, and the time lapse between injury and repair. One crucial factor is using a suitable material with favorable biocompatibility, moisture tolerance, and sealing abilities. Thus, choosing the suitable perforation sealing material can significantly affect the outcomes. Many materials have been suggested for perforation repair. However, searching for an ideal material continues, indicating the complicated nature of root perforations. In this study, three patients, two male and one female, received treatment for root perforation, each varying in the prognosis determinant factors. All cases were managed non-surgically with cold ceramic (CC) as the repairing material. After follow-up, they were clinically and radiographically examined, and all three cases revealed relatively complete healing of the tissues and no signs or symptoms of inflammation. The results obtained from the presented cases indicated CC's sealing ability, biocompatibility, moisture tolerance, and bone and periodontium regeneration, which are essential for successful perforation repair. The favorable healing of the perforation and the elimination of inflammation in every case, as well as the existing literature, support the use of CC as a suitable material for sealing perforations. However, additional clinical research is recommended to further understand CC's qualities and potential.

There are different combinations of multiple primary cancers; however, the combination of breast, esophagus, and renal cancer has been reported in a few cases. Given the rising prevalence of multiple primary cancers over the past decade, understanding the risk factors for early detection is crucial.

Percutaneous sclerotherapy with bleomycin is an effective, minimally invasive treatment for aggressive pediatric hemangiomas, especially when traditional therapies fail. This approach can improve clinical outcomes, including thrombocytopenia resolution and tumor size reduction, with minimal systemic side effects.

In clinical situations of complete rehabilitation with fixed prostheses, mastering each parameter of all restorations (shape, marginal adaptation, proximal and occlusal contacts) proves to be a challenge. The large number of restorations involves many potential adjustments that are time-consuming and lead to final ceramic properties degradation. This clinical report highlights the benefits of using castable patterns in complete fixed prosthetic rehabilitation. Minimal preparations of the teeth were carried out using the conventional mock-up technique. The impressions were then digitized to produce wax and resin patterns (Castable Wax Resin; Formlabs) with a stereolithography 3D printer (Form 2; Formlabs). During oral try-in of patterns, adjustments can be carried out to correct any defects of shape, marginal adaptation, proximal, and occlusal contacts. The definitive restorations were directly pressed from the patterns into lithium disilicate glass-reinforced ceramic (IPS e.max Press; Ivoclar Vivadent) using the lost-wax casting process. Finally, the restorations were placed permanently in the mouth with complete patient satisfaction after 4 years of follow-up. This procedure is intended to reduce ceramic adjustments on definitive restorations. It is especially relevant in complete fixed rehabilitation and in situations where the thickness of ceramic restorations does not allow for try-in before bonding.

Dermatomyositis (DM) is always associated with various types of malignancies in previously published reports. Anti-transcription intermediary factor 1-γ (anti-TIF1-γ) antibody is more prevalent in DM patients with malignancy than in those without malignancy. In this paper, we want to show a possible relation between anti-TIF1-γ and triple-negative breast carcinoma.

Renal angiomyolipoma (AML) are benign tumors incidentally diagnosed during routine radiologic images; nonetheless, AML rupture is uncommon and has been associated with fatal consequences, demanding prompt intervention, especially during pregnancy with symptoms of Wunderlich's syndrome (WS) and atrophied contralateral kidney. We report a 30-year-old pregnant woman who presented with gross hematuria and hypovolemic shock in her seventh month of pregnancy. Magnetic resonance imaging revealed a 15 × 13.5 × 16 cm AML mass in the left kidney, a 5 × 6 cm intrarenal pseudoaneurysm, and a massive retroperitoneal hematoma with an atrophied contralateral right kidney. After achieving hemodynamic stability, selective renal arterial embolization was performed with a successful outcome. She subsequently delivered her baby via cesarean section without complications. In conclusion, although WS due to AML rupture is rare during pregnancy, accurate diagnosis and prompt endovascular treatment should be pursued in cases involving a solitary kidney and associated comorbid conditions to safeguard the lives of both the patient and the baby, stabilize renal function, and prevent catastrophic complications.

Sarcomatoid hepatocellular carcinoma (SHC), which contains variable proportions of sarcomatous and carcinomatous components, is a rare variant of hepatocellular carcinoma and is a special variant of hepatocellular carcinoma. It is highly malignant, progresses rapidly, and has an extremely poor prognosis. However, the molecular pathogenesis of SHC remains unknown. We report a case of a 35-year-old male, previously healthy with no liver disease history, who presented with intermittent fever. Imaging examination during hospitalization revealed focal liver lesions. Without obvious surgical contraindications, right hemihepatectomy, cholecystectomy, and regional lymph node dissection were performed. Postoperative pathology and immunohistochemistry confirmed the diagnosis of SHC. However, due to the financial burden of the disease, the patient and his family chose traditional Chinese medicine as postoperative supplementary treatment rather than targeted drug combined with immunotherapy or other adjuvant therapies. Unfortunately, the patient passed away due to tumor recurrence 8 months after surgery.

The concurrent occurrence of invasive mold infections caused by two distinct fungal species in hematologic patients represents a rare and challenging condition. The mortality rate associated with these invasive fungal infections in neutropenic patients is high, underscoring the importance of timely diagnosis and prompt initiation of appropriate treatment to improve clinical outcomes. Herein, we present a concomitant acute invasive fungal rhinosinusitis (AIFR) and invasive pulmonary fungal infection caused by Aspergillus and Mucoraceae species in a patient with pre-B-cell acute lymphoblastic leukemia. This case highlights the need for further research to optimize outcomes in immunocompromised patients.

Popliteal artery rupture is a rare but life-threatening complication of total knee arthroplasty. In order to prevent dangerous outcomes, such as amputation or death, immediate vascular intervention is needed. This case highlights the importance of intraoperative vigilance and prompt action to mitigate these risks.