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Comparison of Flow Reduction Efficacy of Nominal and Oversized Flow Diverters Using a Novel Measurement-assisted in Silico Method. 使用一种新颖的硅胶辅助测量方法,比较标称导流板和超大导流板的减流效果。
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-23 DOI: 10.1007/s00062-024-01404-4
B. Csippa, Levente Sándor, Gábor Závodszky, I. Szikora, György Paál
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引用次数: 0
Complications During Ozone Therapy as a Result of Malpractice and Lack of Guidelines. 渎职和缺乏指南导致臭氧治疗过程中出现并发症。
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-23 DOI: 10.1007/s00062-024-01412-4
S. Chirumbolo, S. Pandolfi, L. Valdenassi, Marianna Chierchia, M. Franzini
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引用次数: 0
Societies' Communications. 社团通讯。
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-22 DOI: 10.1007/s00062-024-01413-3
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引用次数: 0
Endovascular Thrombectomy for Extensive Infarction (ASPECTS 0-2) in Acute Ischemic Stroke. 急性缺血性脑卒中大面积脑梗死的血管内血栓切除术(ASPECTS 0-2)。
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-22 DOI: 10.1007/s00062-024-01408-0
P. Dhillon, Vinicius Carraro do Nascimento, L. de Villiers, Hal Rice
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引用次数: 0
Multi-Dynamic-Multi-Echo-based MRI for the Pre-Surgical Determination of Sellar Tumor Consistency: a Quantitative Approach for Predicting Lesion Resectability 基于多动态多回波的核磁共振成像在手术前确定ellar肿瘤一致性:预测病变可切除性的定量方法
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-19 DOI: 10.1007/s00062-024-01407-1
Mehmet Salih Yildirim, Victor Ulrich Schmidbauer, Alexander Micko, Lisa Lechner, Michael Weber, Julia Furtner, Stefan Wolfsberger, Intesar-Victoria Malla Houech, Anna Cho, Gregor Dovjak, Gregor Kasprian, Daniela Prayer, Wolfgang Marik

Purpose

Pre-surgical information about tumor consistency could facilitate neurosurgical planning. This study used multi-dynamic-multi-echo (MDME)-based relaxometry for the quantitative determination of pituitary tumor consistency, with the aim of predicting lesion resectability.

Methods

Seventy-two patients with suspected pituitary adenomas, who underwent preoperative 3 T MRI between January 2020 and January 2022, were included in this prospective study. Lesion-specific T1-/T2-relaxation times (T1R/T2R) and proton density (PD) metrics were determined. During surgery, data about tumor resectability were collected. A Receiver Operating Characteristic (ROC) curve analysis was performed to investigate the diagnostic performance (sensitivity/specificity) for discriminating between easy- and hard-to-remove by aspiration (eRAsp and hRAsp) lesions. A Mann-Whitney-U-test was done for group comparison.

Results

A total of 65 participants (mean age, 54 years ± 15, 33 women) were enrolled in the quantitative analysis. Twenty-four lesions were classified as hRAsp, while 41 lesions were assessed as eRAsp. There were significant differences in T1R (hRAsp: 1221.0 ms ± 211.9; eRAsp: 1500.2 ms ± 496.4; p = 0.003) and T2R (hRAsp: 88.8 ms ± 14.5; eRAsp: 137.2 ms ± 166.6; p = 0.03) between both groups. The ROC analysis revealed an area under the curve of 0.72 (95% CI: 0.60–0.85) at p = 0.003 for T1R (cutoff value: 1248 ms; sensitivity/specificity: 78%/58%) and 0.66 (95% CI: 0.53–0.79) at p = 0.03 for T2R (cutoff value: 110 ms; sensitivity/specificity: 39%/96%).

Conclusion

MDME-based relaxometry enables a non-invasive, pre-surgical characterization of lesion consistency and, therefore, provides a modality with which to predict tumor resectability.

目的 手术前了解肿瘤的一致性有助于制定神经外科手术计划。本研究采用基于多动态多回波(MDME)的弛豫测量法对垂体瘤的一致性进行定量测定,旨在预测病变的可切除性。方法这项前瞻性研究纳入了在2020年1月至2022年1月期间接受术前3 T磁共振成像检查的72例疑似垂体腺瘤患者。研究确定了病变特异性T1/T2松弛时间(T1R/T2R)和质子密度(PD)指标。在手术过程中,收集了有关肿瘤可切除性的数据。进行了接收者操作特征曲线(ROC)分析,以研究区分易切除病灶和难切除病灶(ERAsp和hRAsp)的诊断性能(灵敏度/特异性)。结果 共有 65 名参与者(平均年龄为 54 岁±15 岁,33 名女性)参与了定量分析。24 个病灶被归类为 hRAsp,41 个病灶被评估为 eRAsp。两组的 T1R(hRAsp:1221.0 ms ± 211.9;eerasp:1500.2 ms ± 496.4;p = 0.003)和 T2R(hRAsp:88.8 ms ± 14.5;eerasp:137.2 ms ± 166.6;p = 0.03)有明显差异。ROC 分析显示,在 p = 0.003 时,T1R(临界值:1248 ms;敏感性/特异性:78%/58%)的曲线下面积为 0.72(95% CI:0.60-0.85);在 p = 0.003 时,T2R(临界值:1248 ms;敏感性/特异性:78%/58%)的曲线下面积为 0.66(95% CI:0.53-0.79)。结论:基于 MDME 的弛豫测量可在手术前对病变的一致性进行无创鉴定,因此是预测肿瘤可切除性的一种方法。
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引用次数: 0
Is Stent Retraction to ReLieve Arterial Cerebral VaSospasm Caused by SAH (Stent-ReLACSS) Using PRELAX the Long-awaited Solution for Treatment of Posthemorrhagic Cerebral Vasospasm? 使用 PRELAX 进行支架牵引以缓解 SAH 引起的动脉脑血管痉挛(Stent-ReLACSS)是治疗出血性脑血管痉挛后患者期待已久的解决方案吗?
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-18 DOI: 10.1007/s00062-024-01402-6
A. Khanafer, P. von Gottberg, P. Albiña-Palmarola, T. Liebig, M. Forsting, O. Ganslandt, H. Henkes

Purpose

Recent observational studies have indicated the efficacy of stent retriever devices for the treatment of posthemorrhagic cerebral vasospasm (CVS), both by deployment and on-site withdrawal into the microcatheter (stent angioplasty, SA) and deployment followed by retraction through the target vessel similar to thrombectomy (Stent Retraction to reLieve Arterial Cerebral vaSospasm caused by SAH, Stent-ReLACSS). This article reports the findings with each application of pRESET and pRELAX in the treatment of CVS.

Methods

We retrospectively enrolled 25 patients with severe CVS following aneurysmal subarachnoid hemorrhage. For the SA group, a stent retriever or a pRELAX was temporarily deployed into a narrow vessel segment and retrieved into the microcatheter after 3 min. For the Stent-ReLACSS group, a pRELAX was temporarily deployed into a narrow vessel and pulled back unfolded into the internal carotid artery. If intra-arterial vasodilators were administered, they were given exclusively after mechanical vasospasmolysis to maximize the effectiveness of the stent treatment.

Results

In this study fifteen patients and 49 vessels were treated with SA. All were technically successful without periprocedural complications; however, 8/15 patients (53.3%) required additional treatment of the CVS. A total of 10 patients and 23 vessel segments were treated with Stent-ReLACSS. All maneuvers were technically successful without periprocedural complications and all vessels showed significant angiographic improvement. No recurrent CVS requiring further endovascular treatment occurred in-hospital, and neither territorial ischemia in the treated vessels nor vascular injury were observed in follow-up angiography.

Conclusion

Based on the presented data it appears that Stent-ReLACSS with pRELAX does not pose any additional risks when used to treat CVS and might be superior to SA, especially concerning mid-term and long-term efficacy. The mechanism of action may be an effect on the endothelium rather than mechanical vasodilation. As many patients with CVS are diagnosed too late, prophylactic treatment of high-risk patients (e.g., poor grade, young, female) is potentially viable.

目的最近的观察性研究表明,支架回缩器装置治疗出血性脑血管痉挛(CVS)的疗效显著,包括通过部署并现场撤回微导管(支架血管成形术,SA)和部署后通过靶血管回缩,类似于血栓切除术(支架回缩以缓解SAH引起的动脉性脑血管痉挛,Stent-ReLACSS)。方法我们回顾性地纳入了 25 例动脉瘤性蛛网膜下腔出血后严重 CVS 患者。对于 SA 组,在狭窄的血管段临时部署支架回缩器或 pRELAX,3 分钟后将其回收到微导管中。对于 Stent-ReLACSS 组,将 pRELAX 暂时放入狭窄血管,然后将其拉回颈内动脉。如果使用动脉内血管扩张剂,则必须在机械溶解血管后使用,以最大限度地提高支架治疗的效果。所有患者在技术上都很成功,没有出现围手术期并发症;但是,8/15 例患者(53.3%)需要对 CVS 进行额外治疗。共有 10 名患者和 23 个血管段接受了支架-ReLACSS 治疗。所有操作在技术上都很成功,没有出现围手术期并发症,所有血管的血管造影均有明显改善。院内没有发生需要进一步血管内治疗的复发性 CVS,在随访血管造影中也没有观察到治疗血管的局部缺血或血管损伤。结论根据所提供的数据,使用 pRELAX 支架-ReLACSS 治疗 CVS 似乎不会带来任何额外风险,而且可能优于 SA,尤其是在中期和长期疗效方面。其作用机制可能是对内皮的影响,而不是机械性血管扩张。由于许多 CVS 患者确诊太晚,因此对高危患者(如等级低、年轻、女性)进行预防性治疗是可行的。
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引用次数: 0
Perioperative Management of Spinal Arteriovenous Malformation Embolization: Delayed Venous Thrombosis and Implications for Severe Back Pain 脊髓动静脉畸形栓塞术的围手术期管理:延迟性静脉血栓形成及其对严重背痛的影响
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-09 DOI: 10.1007/s00062-024-01403-5
Bikei Ryu, Tatsuki Mochizuki, Shogo Shima, Shinsuke Sato, Tatsuya Inoue, Takakazu Kawamata, Yasunari Niimi

Background and Purpose

The prognosis of untreated spinal arteriovenous malformations (SAVMs) is poor. Embolization plays an important role in the management of intramedullary SAVMs. Delayed aggravation due to spinal venous thrombosis following successful embolization has been reported; however, perioperative management strategies to prevent thrombosis have not been explored. We present our single-center experience of SAVM embolization and perioperative management, including anticoagulation.

Material and Methods

We retrospectively evaluated 18 patients with SAVMs who underwent transarterial embolization. Perioperative anticoagulation therapy was administered to selected patients. We compared the characteristics of the patients, including perioperative management procedures, between those with and without postoperative worsening following embolization.

Results

Acute postoperative worsening within 1 week occurred in 4 (22.2%) patients. Of these, immediate worsening was observed in one patient as a procedure-related complication. Delayed worsening after 24 h was observed in 3 patients, caused by delayed venous thrombosis with severe back pain. Rescue anticoagulation for delayed worsening improved symptoms in two patients. A comparison between patients with and without acute postoperative worsening revealed significant differences in age (median 46.5 vs. 26.5 years, p = 0.009) and the presence of postoperative back pain (75.0% vs. 0%, p = 0.005); however, there was no significant difference in use of selective anticoagulation (p = 0.274).

Conclusion

The results of this study suggest that SAVM embolization can cause acute worsening due to postoperative venous thrombosis with severe back pain, which may be reversed by anticoagulation therapy. Back pain is an important finding that suggests venous thrombosis, and anticoagulation should be urgently administered.

背景和目的未经治疗的脊髓动静脉畸形(SAVM)预后不良。栓塞治疗在髓内脊髓动静脉畸形的治疗中发挥着重要作用。有报道称,栓塞术成功后,脊髓静脉血栓形成会导致病情延迟加重;然而,预防血栓形成的围手术期管理策略尚未得到探讨。我们介绍了单中心的 SAVM 栓塞术和围手术期管理(包括抗凝)经验。对部分患者进行了围手术期抗凝治疗。我们比较了栓塞术后出现和未出现术后恶化的患者的特征,包括围手术期管理程序。其中,一名患者因手术相关并发症而立即出现病情恶化。3名患者的病情在24小时后延迟恶化,原因是延迟性静脉血栓形成并伴有剧烈背痛。两名患者因延迟恶化而接受了抗凝治疗,症状有所改善。对术后急性恶化和未急性恶化的患者进行比较后发现,他们在年龄(中位 46.5 岁对 26.5 岁,P = 0.009)和术后背痛(75.0% 对 0%,P = 0.005)方面存在显著差异。结论本研究结果表明,SAVM 栓塞可导致术后静脉血栓急性恶化,并伴有严重背痛,抗凝治疗可逆转。背痛是提示静脉血栓形成的重要发现,应立即进行抗凝治疗。
{"title":"Perioperative Management of Spinal Arteriovenous Malformation Embolization: Delayed Venous Thrombosis and Implications for Severe Back Pain","authors":"Bikei Ryu, Tatsuki Mochizuki, Shogo Shima, Shinsuke Sato, Tatsuya Inoue, Takakazu Kawamata, Yasunari Niimi","doi":"10.1007/s00062-024-01403-5","DOIUrl":"https://doi.org/10.1007/s00062-024-01403-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background and Purpose</h3><p>The prognosis of untreated spinal arteriovenous malformations (SAVMs) is poor. Embolization plays an important role in the management of intramedullary SAVMs. Delayed aggravation due to spinal venous thrombosis following successful embolization has been reported; however, perioperative management strategies to prevent thrombosis have not been explored. We present our single-center experience of SAVM embolization and perioperative management, including anticoagulation.</p><h3 data-test=\"abstract-sub-heading\">Material and Methods</h3><p>We retrospectively evaluated 18 patients with SAVMs who underwent transarterial embolization. Perioperative anticoagulation therapy was administered to selected patients. We compared the characteristics of the patients, including perioperative management procedures, between those with and without postoperative worsening following embolization.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Acute postoperative worsening within 1 week occurred in 4 (22.2%) patients. Of these, immediate worsening was observed in one patient as a procedure-related complication. Delayed worsening after 24 h was observed in 3 patients, caused by delayed venous thrombosis with severe back pain. Rescue anticoagulation for delayed worsening improved symptoms in two patients. A comparison between patients with and without acute postoperative worsening revealed significant differences in age (median 46.5 vs. 26.5 years, <i>p</i> = 0.009) and the presence of postoperative back pain (75.0% vs. 0%, <i>p</i> = 0.005); however, there was no significant difference in use of selective anticoagulation (<i>p</i> = 0.274).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The results of this study suggest that SAVM embolization can cause acute worsening due to postoperative venous thrombosis with severe back pain, which may be reversed by anticoagulation therapy. Back pain is an important finding that suggests venous thrombosis, and anticoagulation should be urgently administered.</p>","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":"111 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140587162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular Treatment of a Wide-necked Bilobulated Bifurcation Aneurysm using the Woven EndoBridge (WEB) Device 使用 Woven EndoBridge(WEB)装置对宽颈双分叉动脉瘤进行血管内治疗
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-09 DOI: 10.1007/s00062-024-01405-3
Junhyung Kim, Sang Kyu Park, Joonho Chung
{"title":"Endovascular Treatment of a Wide-necked Bilobulated Bifurcation Aneurysm using the Woven EndoBridge (WEB) Device","authors":"Junhyung Kim, Sang Kyu Park, Joonho Chung","doi":"10.1007/s00062-024-01405-3","DOIUrl":"https://doi.org/10.1007/s00062-024-01405-3","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":"111 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140587275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Multiparametric Analysis Combining DSC-MR Perfusion and [18F]FET-PET is Superior to a Single Parameter Approach for Differentiation of Progressive Glioma from Radiation Necrosis. 更正:结合 DSC-MR 灌注和 [18F]FET-PET 的多参数分析在区分进展期胶质瘤和放射性坏死方面优于单一参数方法。
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-04-05 DOI: 10.1007/s00062-024-01398-z
Jürgen Panholzer, G. Malsiner‐Walli, Bettina Grün, Ognian Kalev, Michael Sonnberger, Robert Pichler
{"title":"Correction to: Multiparametric Analysis Combining DSC-MR Perfusion and [18F]FET-PET is Superior to a Single Parameter Approach for Differentiation of Progressive Glioma from Radiation Necrosis.","authors":"Jürgen Panholzer, G. Malsiner‐Walli, Bettina Grün, Ognian Kalev, Michael Sonnberger, Robert Pichler","doi":"10.1007/s00062-024-01398-z","DOIUrl":"https://doi.org/10.1007/s00062-024-01398-z","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":"5 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140736949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
7 T Versus 3 T in the Diagnosis of Small Unruptured Intracranial Aneurysms: Reply to Radojewski et al. 7 T 与 3 T 在诊断小型未破裂颅内动脉瘤中的对比:回复 Radojewski 等人的文章
IF 2.8 3区 医学 Q2 Medicine Pub Date : 2024-03-01 Epub Date: 2023-06-15 DOI: 10.1007/s00062-023-01321-y
Yash Verma, Sairam Ramesh, Arosh S Perera Molligoda Arachchige
{"title":"7 T Versus 3 T in the Diagnosis of Small Unruptured Intracranial Aneurysms: Reply to Radojewski et al.","authors":"Yash Verma, Sairam Ramesh, Arosh S Perera Molligoda Arachchige","doi":"10.1007/s00062-023-01321-y","DOIUrl":"10.1007/s00062-023-01321-y","url":null,"abstract":"","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":" ","pages":"51-52"},"PeriodicalIF":2.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9634120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Clinical Neuroradiology
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