Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.193
A. Urrehman, Syedda Ayesha, F. Ismail, O. Prakash, Zeeshan Uddin
{"title":"IDDF2022-ABS-0139 Endoscopic spectrum of neuroendocrine tumors from different primary origins","authors":"A. Urrehman, Syedda Ayesha, F. Ismail, O. Prakash, Zeeshan Uddin","doi":"10.1136/gutjnl-2022-iddf.193","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.193","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72714284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.201
J. Abalos, Sophia Zamora
BackgroundVarious gastrointestinal (GI) symptoms, including diarrhea, nausea/vomiting and abdominal pain, have been reported in patients with Coronavirus disease 2019 (COVID-19). In this context, the presence of GI symptoms is variably associated with poor clinical outcomes in COVID-19. We aim to determine the outcomes of hospitalized COVID-19 patients with gastrointestinal symptoms.MethodsThis is a retrospective cohort study which used medical records of admitted COVID-19 patients from March 2020 to March 2021 in a tertiary hospital in Pangasinan. Data records were evaluated for the presence of gastrointestinal manifestations, including diarrhea, nausea, vomiting and abdominal pain at the time of admission. A comparison between cases of COVID-19 patients presenting with GI manifestations to controls or COVID-19 patients without GI manifestation was done.ResultsFour hundred three patients were included in the study. Of these, 22.3% presented with gastrointestinal symptoms, while 77.7% comprised the study controls. Diarrhea was the most common GI symptom (10.4%). No statistically significant difference was observed in comorbidities and laboratory findings. Mortality as the primary outcome of the study did not reach statistical significance between cases and controls (13.33% vs. 16.30%, p =0.621). There were also no significant differences observed in the secondary outcomes, mean length of stay, (14 [12–18 days] in cases vs 14 [12- 17.5 days] in controls, p = 0.716) and need for mechanical ventilation (12.22% vs 16.93%, p = 0.329).ConclusionsThe results of the study revealed no association of the GI symptoms to poor outcomes, including a high rate of mortality, prolonged length of stay and increased need for mechanical ventilation.
研究背景2019冠状病毒病(COVID-19)患者出现了腹泻、恶心/呕吐和腹痛等多种胃肠道症状。在这种情况下，胃肠道症状的存在与COVID-19的不良临床结果有不同的相关性。我们的目的是确定有胃肠道症状的住院COVID-19患者的预后。方法采用回顾性队列研究方法，选取巴加西南某三级医院2020年3月至2021年3月收治的新冠肺炎患者病历。评估数据记录是否存在胃肠道表现，包括入院时腹泻、恶心、呕吐和腹痛。将有胃肠道表现的COVID-19患者与对照组或无胃肠道表现的COVID-19患者进行比较。结果共纳入300例患者。其中，22.3%出现胃肠道症状，77.7%为研究对照组。腹泻是最常见的胃肠道症状(10.4%)。在合并症和实验室结果方面没有统计学上的显著差异。死亡率作为研究的主要终点，在病例和对照组之间没有达到统计学意义(13.33% vs. 16.30%， p =0.621)。在次要结局、平均住院时间(病例14天[12- 18天]vs对照组14天[12- 17.5天]，p = 0.716)和机械通气需求(12.22% vs 16.93%， p = 0.329)方面也没有观察到显著差异。结论:研究结果显示胃肠道症状与不良预后(包括高死亡率、住院时间延长和机械通气需求增加)无关联。
{"title":"IDDF2022-ABS-0153 Gastrointestinal manifestations and outcomes in hospitalized COVID-19 patients: a retrospective study","authors":"J. Abalos, Sophia Zamora","doi":"10.1136/gutjnl-2022-iddf.201","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.201","url":null,"abstract":"BackgroundVarious gastrointestinal (GI) symptoms, including diarrhea, nausea/vomiting and abdominal pain, have been reported in patients with Coronavirus disease 2019 (COVID-19). In this context, the presence of GI symptoms is variably associated with poor clinical outcomes in COVID-19. We aim to determine the outcomes of hospitalized COVID-19 patients with gastrointestinal symptoms.MethodsThis is a retrospective cohort study which used medical records of admitted COVID-19 patients from March 2020 to March 2021 in a tertiary hospital in Pangasinan. Data records were evaluated for the presence of gastrointestinal manifestations, including diarrhea, nausea, vomiting and abdominal pain at the time of admission. A comparison between cases of COVID-19 patients presenting with GI manifestations to controls or COVID-19 patients without GI manifestation was done.ResultsFour hundred three patients were included in the study. Of these, 22.3% presented with gastrointestinal symptoms, while 77.7% comprised the study controls. Diarrhea was the most common GI symptom (10.4%). No statistically significant difference was observed in comorbidities and laboratory findings. Mortality as the primary outcome of the study did not reach statistical significance between cases and controls (13.33% vs. 16.30%, p =0.621). There were also no significant differences observed in the secondary outcomes, mean length of stay, (14 [12–18 days] in cases vs 14 [12- 17.5 days] in controls, p = 0.716) and need for mechanical ventilation (12.22% vs 16.93%, p = 0.329).ConclusionsThe results of the study revealed no association of the GI symptoms to poor outcomes, including a high rate of mortality, prolonged length of stay and increased need for mechanical ventilation.","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79497681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.162
Mansour Alourfi, Mahmoud Mosli, M. Alsahafi
{"title":"IDDF2022-ABS-0062 Diagnostic delay of Crohn’s disease in Saudi Arabia: predictors and association with disease complications","authors":"Mansour Alourfi, Mahmoud Mosli, M. Alsahafi","doi":"10.1136/gutjnl-2022-iddf.162","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.162","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84391530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.155
K. Cheng, Kin-Kong Michael Li, Man-Chung Fong
{"title":"IDDF2022-ABS-0048 Clinical outcome of endoscopic balloon dilatation for small bowel stricture in Crohn’s disease using double-balloon enteroscopy","authors":"K. Cheng, Kin-Kong Michael Li, Man-Chung Fong","doi":"10.1136/gutjnl-2022-iddf.155","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.155","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83391313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.190
A. Urrehman, Asma Yaseen, Noman Khan, Mahrukh Ali, Om Prakash, F. Ismail, Zeeshan Uddin, Z. Abbas
BackgroundEndoscopic Ultrasound (EUS) is a well-established mode of intervention for tissue acquisition in solid organs with rapid on-site evaluation (ROSE). In the Covid-19 era, the implementation of infection control mechanisms has led to modified hybrid techniques to get high diagnostic yield for tissue sampling. Combination of Covid-19 SOPs and tissue acquisition method outline this hybrid technique to get a high diagnostic Yield. We share our initial experience of EUS cases performed with this approach without ROSE.MethodsAll 125 cases who underwent EUS-guided biopsy from June 2020 till June 2022 were included. The Procedure was done in a negative pressure room with all SOPs as per institutional guidelines for patient and staff safety with a minimum number of persons during the procedure.ResultsAmong these cases, 85 were male, mean age of 56 years (range 22–90), Mean duration of procedure 28 minutes mean (10–90 min). 91 cases for organs targeted for malignant pathology include pancreas 53, liver 03, lymph nodes 22, subepithelial lesions 10, mediastinal lesions 15, common-bile duct/gall bladder 07, gastric and retroperitoneal 01 case, 13 cases had a multi-targeted biopsy for the additional staging of disease. The number of ‘passes’ with the needle was average 02 with single pass 20, two pass 60, three passes 20, multitarget single pass in 25. Needle size (Franseen design) used for procedures was 22G in 115 cases and 25G in 10. Common tissue diagnoses include pancreatic adenocarcinoma 38, neuroendocrine tumours 06, tuberculosis 07, gastrointestinal stromal tumours 03, leiomyoma 05, lymphoma 06, metastatic renal cell carcinoma 05, squamous cell carcinoma 05, cholangiocarcinoma/gall bladder adenocarcinoma 13, Sarcoma 03, solid pseudopapillary epithelial neoplasm of pancreas (SPEN) 03 and one case for Schwannoma, breast metastasis, accessory spleen, ectopic pancreas, sarcoidosis There were no immediate or early complications in all cases.ConclusionsHybrid EUS in Covid 19 Era has emerged as a useful/cost-effective and safe approach to get tissue yield without the need for ROSE.
{"title":"IDDF2022-ABS-0136 Hybrid endoscopic ultrasound in the covid-19 era for the tissue diagnosis of solid lesions; an initial experience from a tertiary care centre from Pakistan","authors":"A. Urrehman, Asma Yaseen, Noman Khan, Mahrukh Ali, Om Prakash, F. Ismail, Zeeshan Uddin, Z. Abbas","doi":"10.1136/gutjnl-2022-iddf.190","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.190","url":null,"abstract":"BackgroundEndoscopic Ultrasound (EUS) is a well-established mode of intervention for tissue acquisition in solid organs with rapid on-site evaluation (ROSE). In the Covid-19 era, the implementation of infection control mechanisms has led to modified hybrid techniques to get high diagnostic yield for tissue sampling. Combination of Covid-19 SOPs and tissue acquisition method outline this hybrid technique to get a high diagnostic Yield. We share our initial experience of EUS cases performed with this approach without ROSE.MethodsAll 125 cases who underwent EUS-guided biopsy from June 2020 till June 2022 were included. The Procedure was done in a negative pressure room with all SOPs as per institutional guidelines for patient and staff safety with a minimum number of persons during the procedure.ResultsAmong these cases, 85 were male, mean age of 56 years (range 22–90), Mean duration of procedure 28 minutes mean (10–90 min). 91 cases for organs targeted for malignant pathology include pancreas 53, liver 03, lymph nodes 22, subepithelial lesions 10, mediastinal lesions 15, common-bile duct/gall bladder 07, gastric and retroperitoneal 01 case, 13 cases had a multi-targeted biopsy for the additional staging of disease. The number of ‘passes’ with the needle was average 02 with single pass 20, two pass 60, three passes 20, multitarget single pass in 25. Needle size (Franseen design) used for procedures was 22G in 115 cases and 25G in 10. Common tissue diagnoses include pancreatic adenocarcinoma 38, neuroendocrine tumours 06, tuberculosis 07, gastrointestinal stromal tumours 03, leiomyoma 05, lymphoma 06, metastatic renal cell carcinoma 05, squamous cell carcinoma 05, cholangiocarcinoma/gall bladder adenocarcinoma 13, Sarcoma 03, solid pseudopapillary epithelial neoplasm of pancreas (SPEN) 03 and one case for Schwannoma, breast metastasis, accessory spleen, ectopic pancreas, sarcoidosis There were no immediate or early complications in all cases.ConclusionsHybrid EUS in Covid 19 Era has emerged as a useful/cost-effective and safe approach to get tissue yield without the need for ROSE.","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88272846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.250
Xinning Liu, Fei Li, Jie Xu, R. Mao, Bingsheng Huang, Z. Ye
{"title":"IDDF2022-ABS-0271 Deep learning-based classification distinguishes Crohn’s disease and intestinal tuberculosis from histopathological whole slide images","authors":"Xinning Liu, Fei Li, Jie Xu, R. Mao, Bingsheng Huang, Z. Ye","doi":"10.1136/gutjnl-2022-iddf.250","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.250","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"703 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88568055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.153
Z. Nabi, P. Inavolu, M. Ramchandani, Santhosh Darisetty, R. Goud, S. Priya, Nandini Cherpelli
{"title":"IDDF2022-ABS-0043 Risk factors for submucosal fibrosis during per-oral endoscopic myotomy: a prospective study","authors":"Z. Nabi, P. Inavolu, M. Ramchandani, Santhosh Darisetty, R. Goud, S. Priya, Nandini Cherpelli","doi":"10.1136/gutjnl-2022-iddf.153","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.153","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"2015 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87212172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.167
Z. Sharma, A. Garg, R. Puri, R. Sud, S. Bhagat, A. Kathuria, S. Mishra, S. Sud
{"title":"IDDF2022-ABS-0077 New manometric subtypes of hypercontractile esophagus as seen by hrem- going the achalasia way?","authors":"Z. Sharma, A. Garg, R. Puri, R. Sud, S. Bhagat, A. Kathuria, S. Mishra, S. Sud","doi":"10.1136/gutjnl-2022-iddf.167","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.167","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"125 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86042892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.192
A. Urrehman, Noman Khan, Om Prakash, F. Ismail, Zeeshan Uddin
BackgroundPET scan is widely used not only to diagnose malignancy and its staging, but a small proportion of patients do have false-positive results. EUS now is a well-established modality to get tissue diagnosis, and with multi-target approach can help stage disease more accurately with histopathological results. We share our experience with EUS-M cases with different variety of malignancies.MethodsA total of 25 cases underwent EUS-M from June 2020 till June 2022. Informed consent was obtained, and with Covid screen test with PCR was performed before the procedure. Procedures were done with all SOPs as per institutional guidelines. 22G FNB needle was used in 24 cases, 25G needle in 01 case;Franseen design with the capillary suction method was used to obtain visible core samples for histopathology without ROSE. All cases have confirmed the histopathological diagnosis with the same pathology from other site of Biopsy. Order of Biopsy was Nodes→ Liver metastatic lesion→ Primary Tumour. In cases of nodes mediastinal→ porta-hepatis/pancreatic→ Para-aortic. All samples were adequate for making a confirmatory diagnosis on the tissue sample.ResultsAmong total of 25 cases, Age 54 Mean (22–77) with 16 Males. Duration of procedure 38 Minutes Mean (20–85). Cases with multiple lymphadenopathy from different anatomical regions were 09, while other sites included Liver for metastasis and Primary tumour from pancreas/CBD/GB in 16 cases. Multiple site single pass was performed in 24 cases. 19 cases had malignant pathologies. Final diagnosis of the Disease was pancreatic adenocarcinoma 07, NETs 02, Lymphoma 04, GB Adenocarcinoma/Cholangiocarcinoma 06 and metastatic RCC 01, TB 01. 04 cases had benign disease. All procedures were done under Conscious sedation as day care procedure. There were no immediate or early complications in all cases.ConclusionsEUS-M is a safe and accurate modality to stage malignancy with superiority over PET Scan to obtain a histological diagnosis.
{"title":"IDDF2022-ABS-0138 Multi-target endoscopic ultrasound EUS-M guided biopsy is superior to pet scan for staging for malignancies","authors":"A. Urrehman, Noman Khan, Om Prakash, F. Ismail, Zeeshan Uddin","doi":"10.1136/gutjnl-2022-iddf.192","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.192","url":null,"abstract":"BackgroundPET scan is widely used not only to diagnose malignancy and its staging, but a small proportion of patients do have false-positive results. EUS now is a well-established modality to get tissue diagnosis, and with multi-target approach can help stage disease more accurately with histopathological results. We share our experience with EUS-M cases with different variety of malignancies.MethodsA total of 25 cases underwent EUS-M from June 2020 till June 2022. Informed consent was obtained, and with Covid screen test with PCR was performed before the procedure. Procedures were done with all SOPs as per institutional guidelines. 22G FNB needle was used in 24 cases, 25G needle in 01 case;Franseen design with the capillary suction method was used to obtain visible core samples for histopathology without ROSE. All cases have confirmed the histopathological diagnosis with the same pathology from other site of Biopsy. Order of Biopsy was Nodes→ Liver metastatic lesion→ Primary Tumour. In cases of nodes mediastinal→ porta-hepatis/pancreatic→ Para-aortic. All samples were adequate for making a confirmatory diagnosis on the tissue sample.ResultsAmong total of 25 cases, Age 54 Mean (22–77) with 16 Males. Duration of procedure 38 Minutes Mean (20–85). Cases with multiple lymphadenopathy from different anatomical regions were 09, while other sites included Liver for metastasis and Primary tumour from pancreas/CBD/GB in 16 cases. Multiple site single pass was performed in 24 cases. 19 cases had malignant pathologies. Final diagnosis of the Disease was pancreatic adenocarcinoma 07, NETs 02, Lymphoma 04, GB Adenocarcinoma/Cholangiocarcinoma 06 and metastatic RCC 01, TB 01. 04 cases had benign disease. All procedures were done under Conscious sedation as day care procedure. There were no immediate or early complications in all cases.ConclusionsEUS-M is a safe and accurate modality to stage malignancy with superiority over PET Scan to obtain a histological diagnosis.","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74121919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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