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Comparison of Sensory Organisation Test Results in Patients With Ménière's Disease and Vestibular Migraine: A Retrospective, Cross-Sectional Study in a Chinese Cohort 一项中国队列回顾性横断面研究:msamni<e:1>病和前庭偏头痛患者感觉组织测试结果的比较
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-27 DOI: 10.1111/coa.70027
Yangming Leng, Yingzhao Liu, Renhong Zhou, Bo Liu

Objectives

We aimed to characterise the sensory organisation test (SOT) performance and compare the posturographic difference between patients with Ménière's disease (MD) and those with vestibular migraine (VM) in the Chinese population.

Design

This cross-sectional comparative study was conducted in accordance with the STROBE guidelines.

Setting

Tertiary medical centre.

Participants

Seventy-one patients with unilateral definite MD, 57 patients with definite VM, and 58 controls.

Main Outcome Measure

Audiometry, caloric test and SOT were conducted. The balance-related variables included: equilibrium score (ES) in each SOT condition, composite ES and sensory ratios (SOM, VIS, VEST and PREF).

Results

Composite ES and ESs in SOT 5 and 6 were dramatically lower in MD patients than in VM counterparts. For the sensory ratio, the abnormal rate was highest for VIS ratio (31.6%), followed by VEST (19.3%) and PREF ratio (1.8%) in VM patients. In MD patients, the abnormal rate was highest for VEST ratio (42.3%), followed by VIS (32.4%) and PREF ratio (12.7%). Ménière's stage was negatively correlated with ES in SOT 5, composite ES and VEST ratio. In the VM group, ESs (composite and in SOT 1–6) and sensory ratios were not correlated with gender, age or caloric results. Compared with VM patients, MD patients were more likely to have lower or abnormal VEST ratio.

Conclusion

Despite similar clinical manifestations, MD and VM display distinct patterns of balance impairment demonstrated by SOT, which may be associated with different underlying pathophysiological mechanisms. Future study with disease subtyping and phase stratification using comprehensive vestibular tests is warranted.

目的:我们的目的是表征感觉组织测试(SOT)的表现,并比较中国人群中msamimni病(MD)患者和前庭偏头痛(VM)患者的姿势差异。设计:本横断面比较研究按照STROBE指南进行。环境:三级医疗中心。参与者:71例单侧明确MD, 57例明确VM, 58例对照。主要观察指标:听力学、热量测试、SOT。平衡相关变量包括:各SOT条件下的平衡得分(ES)、综合ES和感觉比(SOM、VIS、VEST和PREF)。结果:MD患者sot5和sot6的综合ES和ESs明显低于VM患者。VM患者的感觉比异常率以VIS比最高(31.6%),其次为VEST(19.3%)和PREF比(1.8%)。MD患者中,VEST异常率最高(42.3%),其次是VIS(32.4%)和PREF(12.7%)。在sot5、综合ES和VEST比值中,msamni分期与ES呈负相关。在VM组中,ESs(复合和sot1 -6)和感觉比与性别、年龄或热量结果无关。与VM患者相比,MD患者更容易出现较低或异常的VEST比率。结论:尽管临床表现相似,MD和VM表现出不同的SOT所表现出的平衡障碍模式,这可能与不同的潜在病理生理机制有关。未来的研究与疾病亚型和阶段分层使用综合前庭测试是必要的。
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引用次数: 0
Role of Ipsilateral Nasoseptal Flap in Spontaneous Lateral Recess of Sphenoid Meningoencephalocele Repair by Transpterygoid Approach: A Retrospective Cohort Study 同侧鼻中隔皮瓣在经蝶窦入路修复蝶骨脑膜膨出自发性外侧隐窝中的作用:一项回顾性队列研究。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-23 DOI: 10.1111/coa.70023
Ashwin Gajendran Vedhapoodi, Saravana Selvan Velmurugan, Marimangalam Premchandrababu Chandramouli, Sengottuvelu Palanisamy, Saujanya Saravanakumar
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引用次数: 0
A Prospective Pilot Study of the Efficacy of Oral Propranolol in Reduction of the Frequency and Severity of Epistaxis in Hereditary Haemorrhagic Telangiectasia 口服心得安降低遗传性出血性毛细血管扩张患者出血频率和严重程度的前瞻性先导研究。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-23 DOI: 10.1111/coa.70017
C. Grigg, A. Walker, A. Cervin, K. Girling, Z. Liu, J. Earnshaw
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引用次数: 0
Examining the Impact of Race, Ethnicity, and Language on Pursuit of Cochlear Implantation 考察种族、民族和语言对人工耳蜗植入的影响。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-20 DOI: 10.1111/coa.70020
Aneesh A. Patel, Jessica R. Levi, Peter C. Weber

Introduction

It is unclear whether primary language impacts decision to pursue cochlear implantation (CI) and which factors seen in White patients may account for higher odds of implantation. The aim of this study was to further define factors that contribute to decision to pursue or decline cochlear implantation.

Methods

Retrospective chart review of patients older than 18 years who underwent cochlear implant evaluation (CPT 92626/92627), from January 1, 2017 to October 31, 2023 and were determined to be cochlear implantation candidates was completed. Those who pursued CI were compared to those who did not, in addition to White and non-White patients. T-testing, Chi-square analysis, and multivariate analysis were used to compare the groups.

Results

From January 1, 2017 to October 31, 2023, a total of 93 patients met inclusion criteria, of which 46 (49.5%) underwent CI. White candidates had 4.33 the odds of pursuing cochlear implantation compared to those who were not White (95% CI: 1.15, 1.86; p = 0.04). White candidates and those who did not need interpreters were noted to have significantly higher preoperative scores for bilateral (p < 0.0001) and unilateral AZBio in quiet (p < 0.0001), unilateral Consonant-Nucleus-Consonant (CNC) words, and unilateral CNC phonemes (p < 0.0001) compared to non-White candidates.

Conclusion

White patients had significantly higher odds of pursuing cochlear implantation compared to non-White patients. White patients were noted to have significantly higher preoperative AzBio in quiet and CNC word/phoneme scores compared to non-White patients.

目前尚不清楚母语是否会影响人工耳蜗植入(CI)的决定,以及白人患者中哪些因素可能导致人工耳蜗植入的几率更高。本研究的目的是进一步确定决定是否进行人工耳蜗植入的因素。方法:回顾性回顾2017年1月1日至2023年10月31日接受人工耳蜗植入评估(CPT 92626/92627)的年龄大于18岁且确定为人工耳蜗植入候选人的患者。除了白人和非白人患者外,研究人员还将那些接受CI治疗的患者与没有接受CI治疗的患者进行了比较。采用t检验、卡方分析和多变量分析进行组间比较。结果:2017年1月1日至2023年10月31日,共93例患者符合纳入标准,其中46例(49.5%)行CI。白人候选人与非白人候选人相比,进行人工耳蜗植入的几率为4.33 (95% CI: 1.15, 1.86; p = 0.04)。结论:白人患者与非白人患者相比,寻求人工耳蜗植入术的几率明显更高。与非白人患者相比,白人患者在安静和CNC单词/音素评分方面的术前AzBio明显更高。
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引用次数: 0
Beyond the CBC: Can Novel Markers Predict Recurrence in Chronic Rhinosinusitis With Nasal Polyposis? 超越CBC:新的标志物能预测慢性鼻窦炎伴鼻息肉的复发吗?
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-17 DOI: 10.1111/coa.70024
Hasan Canakci, Hasmet Yazici, Salih Yayman, Kamil Gokce Tulaci, Erhan Arslan, Omer Hizli

Introduction

This study aimed to investigate the potential prognostic value of eosinophil count, eosinophil-monocyte ratio (EMR), total IgE, systemic immune-inflammatory index (SII), systemic inflammation response index (SIRI), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and the presence of asthma and acetylsalicylic acid (ASA) sensitivity in predicting postoperative recurrence in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP).

Methods

Patients with CRSwNP were divided into two groups based on recurrence within 3 years postoperatively: Group 1 (non-recurrent) included patients with no signs of recurrence, and Group 2 (recurrent) included those with endoscopic evidence of recurrence. A control group of age- and gender-matched healthy individuals without any history of inflammation and with normal nasal endoscopy findings was also included. Eosinophil, EMR, total IgE, NLR, PLR, SII, SIRI, and the presence of asthma and ASA sensitivity were compared among the groups.

Results

The recurrent NP group had significantly higher median total IgE and PLR compared to the non-recurrent group (p = 0.036). Compared to controls, the recurrent NP group had significantly elevated eosinophil, EMR, SII, and SIRI levels (p < 0.001, p = 0.022, and p = 0.038, respectively). No significant differences in PLR, SII, or SIRI were found between the non-recurrent and control groups (p = 1). Multivariate logistic regression identified asthma as an independent predictor of recurrence.

Conclusion

EMR, SII, and SIRI may serve as valuable biomarkers in CRSwNP. Their elevated levels in recurrent cases support their potential role in predicting postoperative recurrence.

摘要:本研究旨在探讨嗜酸性粒细胞计数、嗜酸性粒细胞-单核细胞比(EMR)、总IgE、全身免疫炎症指数(SII)、全身炎症反应指数(SIRI)、中性粒细胞-淋巴细胞比(NLR)、血小板-淋巴细胞比(PLR)、哮喘和乙酰水杨酸(ASA)敏感性对慢性鼻窦炎合并鼻息肉(CRSwNP)患者术后复发的潜在预后价值。方法:将CRSwNP患者根据术后3年内的复发情况分为两组:1组(非复发)包括无复发迹象的患者,2组(复发)包括内镜下有复发证据的患者。对照组包括年龄和性别匹配的健康个体,没有任何炎症史,鼻内窥镜检查结果正常。比较各组间嗜酸性粒细胞、EMR、总IgE、NLR、PLR、SII、SIRI、哮喘及ASA敏感性。结果:NP复发组总IgE和PLR中位数明显高于非复发组(p = 0.036)。与对照组相比,复发性NP组嗜酸性粒细胞、EMR、SII和SIRI水平显著升高(p结论:EMR、SII和SIRI可能是CRSwNP中有价值的生物标志物。它们在复发病例中的升高水平支持了它们在预测术后复发中的潜在作用。
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引用次数: 0
An Exploratory Retrospective Study of Clinical Outcomes Following Adenotonsillectomy in Children With Obstructive Sleep Disordered Breathing Living With Severe Obesity 重度肥胖伴阻塞性睡眠呼吸障碍儿童腺扁桃体切除术后临床结果的探索性回顾性研究
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-15 DOI: 10.1111/coa.70022
Zoë A. Burton, Claire Nissenbaum, Manjeevan Singh, Camille Ball, Gurkirat Khokar, Eishaan K. Bhargava, Heather E. Elphick

Introduction

Adenotonsillectomy (AT) to improve obstructive sleep disordered breathing (oSDB) is a common paediatric surgical procedure. Children living with obesity have both an increased risk of oSDB and a higher perioperative risk.

Objectives

We aimed to establish whether AT in children with severe obesity improves clinical symptoms, and whether this correlates with quantifiable sleep studies. A secondary outcome was preoperative change in BMI z-score amongst children attending a specialist anaesthetic clinic.

Methods

A retrospective electronic notes review over a 2-year period identified children 2–16 years living with ‘severe’ obesity undergoing AT for oSDB. Demographic data, BMI and BMI z-score were collated preoperatively and at surgery. Pre- and postoperative quantifiable sleep study data and clinical episodes were examined. Postoperative AHI < 5/ODI4 < 4/h or clinical symptom resolution was considered ‘curative’.

Results

A total of 1007 tonsillectomies were performed for oSDB; 55 met inclusion criteria and 30 underwent preoperative sleep studies. Age ranged from 3 to 15 years (mean 8.7, SD 3.3) with a 2:1 ratio of males to females. Nine children (34.6%) underwent both pre- and postoperative studies with ODI4/AHI ranges of 0.5–121.2/h and 0–9.3/h, respectively. Overall ‘cure’ rate was 42.3%, with postoperative sleep studies confirming clinical findings. Preoperative mean BMI z-score was +3.83 (SD 1.19) with significant reduction at the time of surgery (−0.17, SD 0.29; p = 0.004) following lifestyle intervention (mean 6.0 months; SD 11.7 weeks).

Conclusion

Over half of severely obese children undergoing AT had residual postoperative oSDB symptoms. Sleep studies might identify those benefitting from further intervention. Findings support the effectiveness of preoperative lifestyle intervention, but the impact on symptoms and surgical timing should be further delineated.

腺扁桃体切除术(AT)改善阻塞性睡眠呼吸障碍(oSDB)是一种常见的儿科外科手术。肥胖儿童发生oSDB的风险增加,围手术期风险也较高。目的:我们旨在确定严重肥胖儿童的AT是否能改善临床症状,以及这是否与可量化的睡眠研究相关。次要结果是参加专科麻醉诊所的儿童术前BMI z评分的变化。方法:对2年的回顾性电子记录进行回顾,确定了2-16岁的“严重”肥胖儿童因oSDB接受AT治疗。术前、术中统计统计资料、BMI及BMI z-score。检查了术前和术后可量化的睡眠研究数据和临床发作。术后AHI结果:oSDB共行扁桃体切除术1007例;55人符合纳入标准,30人接受术前睡眠研究。年龄3 ~ 15岁(平均8.7岁,标准差3.3岁),男女比例为2:1。9名儿童(34.6%)接受了术前和术后研究,ODI4/AHI范围分别为0.5-121.2/h和0-9.3/h。总体治愈率为42.3%,术后睡眠研究证实了临床结果。术前平均BMI z-score为+3.83 (SD 1.19),手术时显著降低(-0.17,SD 0.29;P = 0.004),接受生活方式干预(平均6.0个月;SD 11.7周)。结论:超过一半的严重肥胖儿童接受AT手术后存在残留的oSDB症状。睡眠研究可能会确定那些从进一步干预中受益的人。研究结果支持术前生活方式干预的有效性,但对症状和手术时机的影响应进一步确定。
{"title":"An Exploratory Retrospective Study of Clinical Outcomes Following Adenotonsillectomy in Children With Obstructive Sleep Disordered Breathing Living With Severe Obesity","authors":"Zoë A. Burton,&nbsp;Claire Nissenbaum,&nbsp;Manjeevan Singh,&nbsp;Camille Ball,&nbsp;Gurkirat Khokar,&nbsp;Eishaan K. Bhargava,&nbsp;Heather E. Elphick","doi":"10.1111/coa.70022","DOIUrl":"10.1111/coa.70022","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Adenotonsillectomy (AT) to improve obstructive sleep disordered breathing (oSDB) is a common paediatric surgical procedure. Children living with obesity have both an increased risk of oSDB and a higher perioperative risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>We aimed to establish whether AT in children with severe obesity improves clinical symptoms, and whether this correlates with quantifiable sleep studies. A secondary outcome was preoperative change in BMI <i>z</i>-score amongst children attending a specialist anaesthetic clinic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective electronic notes review over a 2-year period identified children 2–16 years living with ‘severe’ obesity undergoing AT for oSDB. Demographic data, BMI and BMI <i>z</i>-score were collated preoperatively and at surgery. Pre- and postoperative quantifiable sleep study data and clinical episodes were examined. Postoperative AHI &lt; 5/ODI4 &lt; 4/h or clinical symptom resolution was considered ‘curative’.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1007 tonsillectomies were performed for oSDB; 55 met inclusion criteria and 30 underwent preoperative sleep studies. Age ranged from 3 to 15 years (mean 8.7, SD 3.3) with a 2:1 ratio of males to females. Nine children (34.6%) underwent both pre- and postoperative studies with ODI4/AHI ranges of 0.5–121.2/h and 0–9.3/h, respectively. Overall ‘cure’ rate was 42.3%, with postoperative sleep studies confirming clinical findings. Preoperative mean BMI <i>z</i>-score was +3.83 (SD 1.19) with significant reduction at the time of surgery (−0.17, SD 0.29; <i>p</i> = 0.004) following lifestyle intervention (mean 6.0 months; SD 11.7 weeks).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Over half of severely obese children undergoing AT had residual postoperative oSDB symptoms. Sleep studies might identify those benefitting from further intervention. Findings support the effectiveness of preoperative lifestyle intervention, but the impact on symptoms and surgical timing should be further delineated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"50 6","pages":"1088-1095"},"PeriodicalIF":1.5,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric Nasal Septal Perforations Systematic Review: Etiologies, Symptoms, and Treatment Outcomes 小儿鼻中隔穿孔系统综述:病因、症状和治疗结果。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-12 DOI: 10.1111/coa.70010
Arjun Sharma, Lana Mamoun, Nihal Punjabi, Roy Qu, Joseph D. Peterson, Jared C. Inman

Objective

To better elucidate the aetiologies, symptomatology, and surgical repair outcomes for nasal septal perforations in the paediatric population.

Study Design

Systematic review and meta-analysis.

Methods

The PubMed, Embase and Web of Science libraries were queried using the terms “nasal septum,” “perforation,” and “paediatric” and all relevant synonyms. All studies that included data on nasal septal perforations in patients aged 0–18 and their etiologies were included.

Results

After 498 studies were reviewed, 9 retrospective studies with 219 patients were included for the primary analysis. The most common etiologies for nasal septal perforations in the literature were iatrogenic (34.25%), traumatic (23.29%), and idiopathic (18.26%). The most reported symptoms were crusting, epistaxis, and nasal obstruction. The overall closure rate for surgical repair was 0.86 [95% CI 0.76–0.95; I2 = 17%]. Closure rates were notably lower in patients with autoimmune, drug, and foreign body related etiologies. There was no clear relationship between perforation size and closure success.

Conclusion

Overall, paediatric nasal septal perforations appear to primarily be caused by iatrogenic and traumatic etiologies. Paediatric patients also experience high proportions of foreign body-related defects. Closure rates remain high for paediatric patients with nasal septal perforations.

目的:更好地阐明小儿鼻中隔穿孔的病因、症状和手术修复效果。研究设计:系统评价和荟萃分析。方法:使用“鼻中隔”、“穿孔”、“儿科”和所有相关同义词查询PubMed、Embase和Web of Science图书馆。所有包括0-18岁患者鼻中隔穿孔及其病因的研究均被纳入。结果:在回顾了498项研究后,9项回顾性研究纳入了219例患者进行初步分析。文献中鼻中隔穿孔最常见的病因是医源性(34.25%)、外伤性(23.29%)和特发性(18.26%)。报告最多的症状是结痂、鼻出血和鼻塞。手术修复的总闭合率为0.86 [95% CI 0.76-0.95;i2 = 17%]。在自身免疫、药物和异物相关病因的患者中,闭合率明显较低。穿孔大小与闭合成功之间没有明确的关系。结论:总的来说,小儿鼻中隔穿孔似乎主要是由医源性和外伤性病因引起的。儿科患者也有很高比例的异物相关缺陷。小儿鼻中隔穿孔的闭合率仍然很高。
{"title":"Paediatric Nasal Septal Perforations Systematic Review: Etiologies, Symptoms, and Treatment Outcomes","authors":"Arjun Sharma,&nbsp;Lana Mamoun,&nbsp;Nihal Punjabi,&nbsp;Roy Qu,&nbsp;Joseph D. Peterson,&nbsp;Jared C. Inman","doi":"10.1111/coa.70010","DOIUrl":"10.1111/coa.70010","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To better elucidate the aetiologies, symptomatology, and surgical repair outcomes for nasal septal perforations in the paediatric population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Systematic review and meta-analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The PubMed, Embase and Web of Science libraries were queried using the terms “nasal septum,” “perforation,” and “paediatric” and all relevant synonyms. All studies that included data on nasal septal perforations in patients aged 0–18 and their etiologies were included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After 498 studies were reviewed, 9 retrospective studies with 219 patients were included for the primary analysis. The most common etiologies for nasal septal perforations in the literature were iatrogenic (34.25%), traumatic (23.29%), and idiopathic (18.26%). The most reported symptoms were crusting, epistaxis, and nasal obstruction. The overall closure rate for surgical repair was 0.86 [95% CI 0.76–0.95; <i>I</i><sup>2</sup> = 17%]. Closure rates were notably lower in patients with autoimmune, drug, and foreign body related etiologies. There was no clear relationship between perforation size and closure success.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Overall, paediatric nasal septal perforations appear to primarily be caused by iatrogenic and traumatic etiologies. Paediatric patients also experience high proportions of foreign body-related defects. Closure rates remain high for paediatric patients with nasal septal perforations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"50 6","pages":"1082-1087"},"PeriodicalIF":1.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Operative Management of Cholesteatoma in the Elderly: A 15-Year Retrospective Study 老年胆脂瘤手术治疗的结果:一项15年回顾性研究。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-08 DOI: 10.1111/coa.70019
Dimitrios Daskalakis, Emily G. Heywood, Rahil Mandalia, Anil Banerjee, Peter Rea, Paramita Baruah
{"title":"Outcomes of Operative Management of Cholesteatoma in the Elderly: A 15-Year Retrospective Study","authors":"Dimitrios Daskalakis,&nbsp;Emily G. Heywood,&nbsp;Rahil Mandalia,&nbsp;Anil Banerjee,&nbsp;Peter Rea,&nbsp;Paramita Baruah","doi":"10.1111/coa.70019","DOIUrl":"10.1111/coa.70019","url":null,"abstract":"","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"50 6","pages":"1114-1122"},"PeriodicalIF":1.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric Obstructive Sleep Disordered Breathing: Cardiovascular Changes After Adenotonsillectomy 儿童阻塞性睡眠呼吸障碍:腺扁桃体切除术后的心血管变化。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-08 DOI: 10.1111/coa.70018
Francisco Alves de Sousa, Marta Rios, Paula Branco, Sara Raquel Azevedo, Mariline Santos, Manuel Ferreira de Magalhães

Introduction

Obstructive sleep disordered breathing (OSDB) is prevalent in children and often associated with adenotonsillar hypertrophy (ATH). This prospective study investigated the impact of adenotonsillectomy on cardiovascular parameters in children with ATH and suspected OSDB, employing a generalised estimating equation (GEE) approach to account for repeated measures and potential confounders.

Methods

Children (4–14 years) with ATH and clinical OSDB undergoing adenotonsillectomy were included. Pre- and post-operative resting heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), weight, and estimated cardiac output (COEst) were assessed. Paired t-tests and Wilcoxon signed-rank tests were used for pre-post comparisons, while GEE models examined the influence of time (surgery), age, gender, and their interactions on the outcomes.

Results

A total of 90 children (mean age: 6.86 ± 2.78 years) participated. Adenotonsillectomy resulted in a significant decrease in HR (p = 0.028) and COEst (p = 0.003). No significant changes were observed in SBP or DBP (p > 0.05). A significant negative correlation was found between the change in COEst and age (Spearman's rho = −0.349, p < 0.001), indicating a more pronounced reduction in COEst in younger children.

Conclusion

Adenotonsillectomy in children with ATH and clinical OSDB may lead to significant variations in resting heart rate and estimated cardiac output after surgery. This suggests a potential reduction in resting sympathetic activity following the resolution of upper airway obstruction, with a possible contribution of age-related factors to the observed cardiovascular responses to adenotonsillectomy.

梗阻性睡眠呼吸障碍(OSDB)在儿童中很普遍,通常与腺扁桃体肥大(ATH)有关。这项前瞻性研究调查了腺扁桃体切除术对ATH和疑似OSDB儿童心血管参数的影响,采用广义估计方程(GEE)方法来考虑重复测量和潜在混杂因素。方法:对行腺扁桃体切除术的ATH和临床OSDB患儿(4-14岁)进行分析。评估术前和术后静息心率(HR)、收缩压(SBP)、舒张压(DBP)、体重和估计心输出量(COEst)。配对t检验和Wilcoxon符号秩检验用于前后比较,而GEE模型检验了时间(手术)、年龄、性别及其相互作用对结果的影响。结果:共有90名儿童参与,平均年龄:6.86±2.78岁。腺扁桃体切除术导致HR (p = 0.028)和COEst (p = 0.003)显著降低。收缩压和舒张压无明显变化(p < 0.05)。COEst变化与年龄呈显著负相关(Spearman’s rho = -0.349, p)。结论:ATH患儿腺扁桃体切除术和临床OSDB可能导致术后静息心率和估计心输出量发生显著变化。这表明在上呼吸道阻塞解除后,静息交感神经活动可能会减少,可能与年龄相关的因素对腺扁桃体切除术后观察到的心血管反应有关。
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引用次数: 0
Defining the Terminology for Acute Ear Discharge in Children: Systematic Review and Expert Consensus Using the Nominal Group Technique 定义儿童急性耳部溢液术语:系统评价和专家共识使用名义组技术。
IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-06 DOI: 10.1111/coa.70021
Elliot Heward, James Dempsey, Amy McGovarin, John Molloy, Mark Wilbourn, Eason Sivayoham, Merijam Kikic, Jaya R. Nichani, Iain A. Bruce

Background

Acute otitis media (AOM) is one of the most frequent paediatric infections. In approximately 15% of children with AOM, the tympanic membrane perforates, leading to ear discharge. This subset of children is usually more unwell and may need different treatment than those without a perforation. Therefore, terminology is required to differentiate this population from AOM without perforation. Using a consensus exercise, we aimed to standardise disease terminology for this patient group.

Methods

A systematic review was performed using OVID Embase to identify the terminology used within the current published literature. The RAND version of the Nominal Group Technique was then used to gain consensus using an expert panel.

Results

The systematic review identified 2012 abstracts which were reviewed, of which 29 manuscripts were included. A total of nine different definitions were identified within the literature. The expert panel concluded that the terminology ‘acute otitis media with discharge (AOMd)’ should be used when diagnosing a child with an acutely discharging ear of up to 6 weeks duration. Recurrent disease should be diagnosed when four or greater episodes occur per year. Within this disease context, the panel determined the optimal research question was to identify the best management option.

Conclusion

This consensus process has proposed the terminology that should be applied for children with acute ear discharge secondary to AOM. The use of standardised terminology is essential to improve patient care and ensure homogeneity across future research.

背景:急性中耳炎(AOM)是最常见的儿科感染之一。在大约15%的急性中耳炎患儿中,鼓膜穿孔导致耳液流出。这部分儿童通常更不舒服,可能需要与没有穿孔的儿童不同的治疗。因此,需要用术语来区分这种人群和没有穿孔的AOM。使用共识练习,我们旨在标准化该患者组的疾病术语。方法:使用OVID Embase进行系统回顾,以确定当前已发表文献中使用的术语。然后使用RAND版本的名义组技术,通过专家小组获得共识。结果:系统综述共纳入文献摘要2012篇,其中纳入29篇。文献中共有九种不同的定义。专家小组得出的结论是,在诊断持续时间长达6周的儿童耳部急性流出性中耳炎时,应使用术语“急性流出性中耳炎(AOMd)”。当每年发生四次或更多次发作时,应诊断为复发性疾病。在这种疾病背景下,专家组确定最佳研究问题是确定最佳管理方案。结论:这一共识过程提出了应适用于急性中耳炎继发的儿童耳流的术语。标准化术语的使用对于改善患者护理和确保未来研究的同质性至关重要。
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引用次数: 0
期刊
Clinical Otolaryngology
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