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Affective EEG-based cross-session person identification using hierarchical graph embedding 利用分层图嵌入进行基于情感脑电图的跨会期人员识别
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-29 DOI: 10.1007/s11571-024-10132-x
Honggang Liu, Xuanyu Jin, Dongjun Liu, Wanzeng Kong, Jiajia Tang, Yong Peng

The electroencephalogram (EEG) signal is being investigated as a more confidential biometric for person identification. Despite recent advancements, a persistent challenge lies in the influence of variations in affective states. Affective states consistently exist during data collection, regardless of the protocol used. Additionally, the inherently non-stationary nature of EEG makes it susceptible to fluctuations in affective states over time. Therefore, it would be highly crucial to perform precise EEG-based person identification under varying affective states. This paper employed an integrated Multi-scale Convolution and Graph Pooling network (MCGP) to mitigate the impact of affective state variations. MCGP utilized multiple 1D convolutions at different scales to dynamically extract and fuse features. Additionally, a graph pooling layer with an attention mechanism was incorporated to generate hierarchical graph embeddings. These embeddings were concatenated as inputs for a fully connected classification layer. Experiments were conducted on the SEED and SEED-V dataset, revealing that MCGP achieved an average accuracy of 85.51% for SEED and 88.69% for SEED-V in cross-session conditions involving mixed affective states. Under single affective state cross-session scenario, MCGP achieved an average accuracy of 85.75% for SEED and 88.06% for SEED-V for the same affective states, while obtaining 79.57% for SEED and 84.52% for SEED-V for different affective states. Results indicated that, compared to the baseline methods, MCGP effectively mitigated the impact of variations in affective states across different sessions. In single affective state cross-session scenario, identification performance for the same affective states was slightly higher than that for different affective states.

脑电图(EEG)信号作为一种更保密的生物识别技术,正在被研究用于人员识别。尽管最近取得了进步,但持续存在的挑战在于情感状态变化的影响。在数据采集过程中,无论使用何种协议,情绪状态都会持续存在。此外,脑电图固有的非稳态特性使其容易受到情感状态随时间波动的影响。因此,在不同情感状态下进行基于脑电图的精确人员识别至关重要。本文采用了一个集成的多尺度卷积和图池化网络(MCGP)来减轻情感状态变化的影响。MCGP 利用不同尺度的多个一维卷积来动态提取和融合特征。此外,还加入了具有注意力机制的图池层,以生成分层图嵌入。这些嵌入被串联起来,作为全连接分类层的输入。在 SEED 和 SEED-V 数据集上进行的实验表明,在涉及混合情感状态的交叉会话条件下,MCGP 对 SEED 的平均准确率为 85.51%,对 SEED-V 的平均准确率为 88.69%。在单一情感状态交叉会话情况下,对于相同情感状态,MCGP 的 SEED 平均准确率为 85.75%,SEED-V 平均准确率为 88.06%;对于不同情感状态,MCGP 的 SEED 平均准确率为 79.57%,SEED-V 平均准确率为 84.52%。结果表明,与基线方法相比,MCGP 有效地减轻了不同会话中情感状态变化的影响。在单一情感状态跨时段情景下,相同情感状态的识别性能略高于不同情感状态的识别性能。
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引用次数: 0
PSPN: Pseudo-Siamese Pyramid Network for multimodal emotion analysis PSPN:用于多模态情感分析的伪暹罗金字塔网络
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-28 DOI: 10.1007/s11571-024-10123-y
Yanyan Yin, Wanzeng Kong, Jiajia Tang, Jinghao Li, Fabio Babiloni

Emotion recognition plays an important role in human life and healthcare. The EEG has been extensively researched as an objective indicator of intense emotions. However, current existing methods lack sufficient analysis of shallow and deep EEG features. In addition, human emotions are complex and variable, making it difficult to comprehensively represent emotions using a single-modal signal. As a signal associated with gaze tracking and eye movement detection, Eye-related signals provide various forms of supplementary information for multimodal emotion analysis. Therefore, we propose a Pseudo-Siamese Pyramid Network (PSPN) for multimodal emotion analysis. The PSPN model employs a Depthwise Separable Convolutional Pyramid (DSCP) to extract and integrate intrinsic emotional features at various levels and scales from EEG signals. Simultaneously, we utilize a fully connected subnetwork to extract the external emotional features from eye-related signals. Finally, we introduce a Pseudo-Siamese network that integrates a flexible cross-modal dual-branch subnetwork to collaboratively utilize EEG emotional features and eye-related behavioral features, achieving consistency and complementarity in multimodal emotion recognition. For evaluation, we conducted experiments on the DEAP and SEED-IV public datasets. The experimental results demonstrate that multimodal fusion significantly improves the accuracy of emotion recognition compared to single-modal approaches. Our PSPN model achieved the best accuracy of 96.02% and 96.45% on the valence and arousal dimensions of the DEAP dataset, and 77.81% on the SEED-IV dataset, respectively. Our code link is: https://github.com/Yinyanyan003/PSPN.git.

情绪识别在人类生活和医疗保健中发挥着重要作用。脑电图作为强烈情绪的客观指标已被广泛研究。然而,现有方法缺乏对浅层和深层脑电图特征的充分分析。此外,人类的情绪复杂多变,很难通过单一模态信号来全面表达情绪。作为一种与注视跟踪和眼动检测相关的信号,眼动相关信号为多模态情绪分析提供了多种形式的补充信息。因此,我们提出了一种用于多模态情感分析的伪暹罗金字塔网络(PSPN)。PSPN 模型采用深度可分离卷积金字塔(DSCP)从脑电信号中提取并整合不同层次和尺度的内在情绪特征。同时,我们利用全连接子网络从眼部相关信号中提取外部情绪特征。最后,我们引入了一个伪连通网络(Pseudo-Siamese network),该网络整合了一个灵活的跨模态双分支子网络,协同利用脑电图情感特征和眼部相关行为特征,实现多模态情感识别的一致性和互补性。为了进行评估,我们在 DEAP 和 SEED-IV 公共数据集上进行了实验。实验结果表明,与单模态方法相比,多模态融合能显著提高情绪识别的准确性。我们的 PSPN 模型在 DEAP 数据集的情感维度和唤醒维度上分别达到了 96.02% 和 96.45% 的最佳准确率,在 SEED-IV 数据集上达到了 77.81% 的最佳准确率。我们的代码链接是:https://github.com/Yinyanyan003/PSPN.git。
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引用次数: 0
A novel dual-step transfer framework based on domain selection and feature alignment for motor imagery decoding 基于领域选择和特征对齐的新型运动图像解码双步转移框架
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-25 DOI: 10.1007/s11571-023-10053-1
Guanglian Bai, Jing Jin, Ren Xu, Xingyu Wang, Andrzej Cichocki

In brain-computer interfaces (BCIs) based on motor imagery (MI), reducing calibration time is gradually becoming an urgent issue in practical applications. Recently, transfer learning (TL) has demonstrated its effectiveness in reducing calibration time in MI-BCI. However, the different data distribution of subjects greatly affects the application effect of TL in MI-BCI. Therefore, this paper combines data alignment, source domain selection, and feature alignment into the MI-TL. We propose a novel dual-step transfer framework based on source domain selection and feature alignment. First, the source and target domains are aligned using a pre-calibration strategy (PS), and then a sequential reverse selection method is proposed to match the optimal source domain for each target domain with the designed dual model selection strategy. We use filter bank regularization common space pattern (FBRCSP) to obtain more features and introduce manifold embedded distribution alignment (MEDA) to correct the prediction results of the support vector machine (SVM). The experimental results on two competition public datasets (BCI competition IV Dataset 1 and Dataset 2a) and our dataset show that the average classification accuracy of the proposed framework is higher than the baseline method (no domain selection and no feature alignment), which reaches 84.12%, 79.91%, and 78.45%, respectively. And the computational cost is reduced by half compared with the baseline method.

在基于运动图像(MI)的脑机接口(BCI)中,缩短校准时间逐渐成为实际应用中的一个紧迫问题。最近,迁移学习(TL)在减少运动图像脑机接口(MI-BCI)的校准时间方面显示了其有效性。然而,受试者数据分布的不同在很大程度上影响了迁移学习在 MI-BCI 中的应用效果。因此,本文将数据校准、源域选择和特征校准结合到 MI-TL 中。我们提出了一种基于源域选择和特征配准的新型双步传输框架。首先,使用预校准策略(PS)对源域和目标域进行对齐,然后提出一种顺序反向选择方法,通过设计的双模型选择策略为每个目标域匹配最佳源域。我们使用滤波器组正则化公共空间模式(FBRCSP)来获取更多特征,并引入流形嵌入分布对齐(MEDA)来修正支持向量机(SVM)的预测结果。在两个竞赛公开数据集(BCI竞赛IV数据集1和数据集2a)和我们的数据集上的实验结果表明,拟议框架的平均分类准确率高于基线方法(无域选择和无特征对齐),分别达到84.12%、79.91%和78.45%。与基线方法相比,计算成本减少了一半。
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引用次数: 0
Development of a humanoid robot control system based on AR-BCI and SLAM navigation 开发基于 AR-BCI 和 SLAM 导航的仿人机器人控制系统
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-18 DOI: 10.1007/s11571-024-10122-z
Yao Wang, Mingxing Zhang, Meng Li, Hongyan Cui, Xiaogang Chen

Brain-computer interface (BCI)-based robot combines BCI and robotics technology to realize the brain’s intention to control the robot, which not only opens up a new way for the daily care of the disabled individuals, but also provides a new way of communication for normal people. However, the existing systems still have shortcomings in many aspects such as friendliness of human–computer interaction, and interaction efficient. This study developed a humanoid robot control system by integrating an augmented reality (AR)-based BCI with a simultaneous localization and mapping (SLAM)-based scheme for autonomous indoor navigation. An 8-target steady-state visual evoked potential (SSVEP)-based BCI was implemented to enable direct control of the humanoid robot by the user. A Microsoft HoloLens was utilized to display visual stimuli for eliciting SSVEPs. Filter bank canonical correlation analysis (FBCCA), a training-free method, was used to detect SSVEPs in this study. By leveraging SLAM technology, the proposed system alleviates the need for frequent control commands transmission from the user, thereby effectively reducing their workload. Online results from 12 healthy subjects showed this developed BCI system was able to select a command out of eight potential targets with an average accuracy of 94.79%. The autonomous navigation subsystem enabled the humanoid robot to autonomously navigate to a destination chosen utilizing the proposed BCI. Furthermore, all participants successfully completed the experimental task using the developed system without any prior training. These findings illustrate the feasibility of the developed system and its potential to contribute novel insights into humanoid robots control strategies.

基于脑机接口(BCI)的机器人将BCI与机器人技术相结合,实现了大脑对机器人的意向控制,不仅为残疾人的日常护理开辟了一条新途径,也为正常人提供了一种新的交流方式。然而,现有系统在人机交互的友好性、交互效率等诸多方面仍存在不足。本研究通过将基于增强现实(AR)的生物识别(BCI)与基于同步定位和映射(SLAM)的室内自主导航方案相结合,开发了一种仿人机器人控制系统。该系统实施了基于8目标稳态视觉诱发电位(SSVEP)的BCI,使用户能够直接控制仿人机器人。微软HoloLens用于显示视觉刺激,以诱发SSVEP。滤波器组典型相关分析(FBCCA)是一种无需训练的方法,在本研究中用于检测 SSVEPs。通过利用 SLAM 技术,拟议的系统减轻了用户频繁发送控制指令的需要,从而有效减轻了用户的工作量。12 名健康受试者的在线结果显示,所开发的 BCI 系统能够从 8 个潜在目标中选择一个指令,平均准确率为 94.79%。自主导航子系统使仿人机器人能够自主导航到利用所提出的生物识别(BCI)技术选择的目的地。此外,所有参与者都使用开发的系统成功完成了实验任务,而无需事先接受任何培训。这些研究结果表明了所开发系统的可行性及其为仿人机器人控制策略提供新见解的潜力。
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引用次数: 0
Chaos analysis of nonlinear variable order fractional hyperchaotic Chen system utilizing radial basis function neural network 利用径向基函数神经网络对非线性变阶分数超混沌陈系统进行混沌分析
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-18 DOI: 10.1007/s11571-024-10118-9
Sadam Hussain, Zia Bashir, M. G. Abbas Malik

This research explores the various chaotic features of the hyperchaotic Chen dynamical system within a variable order fractional (VOF) calculus framework, employing an innovative approach with a nonlinear and adaptive radial basis function neural network. The study begins by computing the numerical solution of VOF differential equations for the hyperchaotic Chen system through a numerical scheme using the Caputo–Fabrizio derivative across a spectrum of different system control parameters. Subsequently, a comprehensive parametric model is formulated using RBFNN, considering the system’s various initial values. We systematically investigate the various chaotic attractors of the proposed system, employing statistical analysis, phase space reconstruction, and Lyapunov exponent. Additionally, we assess the effectiveness of the proposed computational RBFNN model using the Root Mean Square Error statistic. Importantly, the obtained results closely align with those derived from numerical algorithms, emphasizing the high accuracy and reliability of the designed network. The outcomes of this study have implications for studying chaos with variable fractional derivatives, with applications across various scientific and engineering domains. This work advances the understanding and applications of variable order fractional dynamics.

本研究在变阶分数(VOF)微积分框架内,采用非线性和自适应径向基函数神经网络的创新方法,探索了超混沌陈氏动力系统的各种混沌特征。研究首先通过使用卡普托-法布里齐奥导数的数值方案,计算超混沌陈系统的 VOF 微分方程的数值解,并跨越不同的系统控制参数谱。随后,考虑到系统的各种初始值,使用 RBFNN 建立了一个综合参数模型。我们利用统计分析、相空间重构和 Lyapunov 指数,系统地研究了拟议系统的各种混沌吸引子。此外,我们还利用均方根误差统计量评估了所提出的 RBFNN 计算模型的有效性。重要的是,所获得的结果与数值算法得出的结果非常接近,强调了所设计网络的高准确性和可靠性。这项研究的成果对研究具有可变分数导数的混沌具有重要意义,可应用于各种科学和工程领域。这项工作推动了对变阶分数动力学的理解和应用。
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引用次数: 0
Quantifying harmony between direct and indirect pathways in the basal ganglia: healthy and Parkinsonian states 量化基底神经节直接和间接通路之间的协调性:健康状态和帕金森病状态
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-16 DOI: 10.1007/s11571-024-10119-8
Sang-Yoon Kim, Woochang Lim

The basal ganglia (BG) show a variety of functions for motor and cognition. There are two competitive pathways in the BG; direct pathway (DP) which facilitates movement and indirect pathway (IP) which suppresses movement. It is well known that diverse functions of the BG may be made through “balance” between DP and IP. But, to the best of our knowledge, so far no quantitative analysis for such balance was done. In this paper, as a first time, we introduce the competition degree ({{mathcal {C}}}_d) between DP and IP. Then, by employing ({{mathcal {C}}}_d), we quantify their competitive harmony (i.e., competition and cooperative interplay), which could lead to improving our understanding of the traditional “balance” so clearly and quantitatively. We first consider the case of normal dopamine (DA) level of (phi ^*=0.3). In the case of phasic cortical input (10 Hz), a healthy state with ({{mathcal {C}}}_d^* = 2.82) (i.e., DP is 2.82 times stronger than IP) appears. In this case, normal movement occurs via harmony between DP and IP. Next, we consider the case of decreased DA level, (phi = phi ^*(=0.3)~x_{DA}) ((1 > x_{DA} ge 0)). With decreasing (x_{DA}) from 1, the competition degree ({{mathcal {C}}}_d) between DP and IP decreases monotonically from ({{mathcal {C}}}_d^*), which results in appearance of a pathological Parkinsonian state with reduced ({{mathcal {C}}}_d). In this Parkinsonian state, strength of IP is much increased than that in the case of normal healthy state, leading to disharmony between DP and IP. Due to such break-up of harmony between DP and IP, impaired movement occurs. Finally, we also study treatment of the pathological Parkinsonian state via recovery of harmony between DP and IP.

基底神经节(BG)在运动和认知方面具有多种功能。基底节有两条竞争性通路:促进运动的直接通路(DP)和抑制运动的间接通路(IP)。众所周知,BG 的各种功能可能是通过 DP 和 IP 之间的 "平衡 "实现的。但是,据我们所知,迄今为止还没有对这种平衡进行过定量分析。本文首次引入了 DP 和 IP 之间的竞争度({{mathcal {C}}_d )。然后,通过使用 ({{mathcal {C}}}_d) 来量化它们之间的竞争和谐性(即竞争与合作的相互作用),这将有助于我们更清晰、更定量地理解传统的 "平衡"。我们首先考虑多巴胺(DA)水平正常的情况(phi ^*=0.3)。在大脑皮层相位输入(10 Hz)的情况下,会出现一个健康的状态,即 ({{mathcal {C}}}_d^* = 2.82) (即 DP 比 IP 强 2.82 倍)。在这种情况下,正常运动是通过 DP 和 IP 之间的协调来实现的。接下来,我们考虑DA水平下降的情况,(phi = phi ^*(=0.3)~x_{DA}) ((1 > x_{DA} ge 0)).随着 (x_{DA}) 从 1 开始递减,DP 和 IP 之间的竞争程度 ({{mathcal {C}}}_d^*) 从 ({{mathcal {C}}}_d^*) 开始单调递减,这导致了帕金森病理状态的出现,同时 ({{mathcal {C}}}_d) 减少。在这种帕金森状态下,IP 的强度远高于正常健康状态下的强度,从而导致 DP 和 IP 之间的不和谐。由于 DP 和 IP 之间的和谐被打破,运动就会受损。最后,我们还研究了通过恢复 DP 和 IP 之间的和谐来治疗病理性帕金森状态。
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引用次数: 0
Multiresolution feature fusion for smart diagnosis of schizophrenia in adolescents using EEG signals 利用脑电信号多分辨率特征融合智能诊断青少年精神分裂症
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-11 DOI: 10.1007/s11571-024-10120-1
Rakesh Ranjan, Bikash Chandra Sahana

Numerous studies on early detection of schizophrenia (SZ) have utilized all available channels or employed set of a few time domain or frequency domain features, while a limited number of features may not be sufficient enough to perform diagnosis efficiently. To encounter these problems, an automated diagnosis model is proposed for the efficient diagnosis of schizophrenia symptomatic adolescent subjects from electroencephalogram (EEG) signals via machine intelligence. A publicly accessible EEG dataset featuring 16-channels EEG obtained from 84 adolescents (45 SZ symptomatic and 39 healthy control) is used to demonstrate the work. Initially, the signals are decomposed into sub-bands using two multi-resolution signal analysis methods: Empirical Wavelet Transform and Empirical mode decomposition. 75 unique features from each sub-bands are extracted and the few selective prominent features are applied to machine learning classifiers for optimal sub-band selection. Subsequently, a hybrid model is proposed, combining convolutional neural network (CNN) and ensemble bagged tree, incorporating both deep learning and handcrafted features to perform SZ diagnosis. This innovative model achieved superior classification performance compared to existing methods, offering a promising approach for SZ diagnosis. Furthermore, the study explores the impact of different brain regions and combined regional data in SZ diagnosis comprehensively. Hence, this computer-assisted decision-making model minimizes the limitations of prior studies by providing a more robust and efficient diagnostic system for schizophrenia.

有关精神分裂症(SZ)早期检测的大量研究利用了所有可用的通道或采用了一组少数时域或频域特征,而有限的特征数量可能不足以有效地进行诊断。针对这些问题,我们提出了一种自动诊断模型,通过机器智能从脑电图(EEG)信号中高效诊断出有精神分裂症症状的青少年受试者。我们使用了一个可公开访问的脑电图数据集,该数据集由 84 名青少年(45 名有精神分裂症症状的青少年和 39 名健康对照组青少年)的 16 通道脑电图组成。首先,使用两种多分辨率信号分析方法将信号分解为子带:经验小波变换和经验模式分解。从每个子波段中提取 75 个独特特征,并将少数几个选择性突出特征应用于机器学习分类器,以优化子波段选择。随后,提出了一种混合模型,将卷积神经网络(CNN)和集合袋装树相结合,结合深度学习和手工特征来进行 SZ 诊断。与现有方法相比,这一创新模型实现了更优越的分类性能,为 SZ 诊断提供了一种前景广阔的方法。此外,该研究还全面探讨了不同脑区和综合区域数据对 SZ 诊断的影响。因此,该计算机辅助决策模型最大限度地减少了以往研究的局限性,为精神分裂症提供了一个更稳健、更高效的诊断系统。
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引用次数: 0
Sonification of electronic dynamical systems: Spectral characteristics and sound evaluation using EEG features 电子动力系统的声学化:利用脑电图特征进行频谱特征和声音评估
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-09 DOI: 10.1007/s11571-024-10112-1
G. Acosta Martínez, E. Guevara, E. S. Kolosovas-Machuca, P. G. Rodrigues, D. C. Soriano, E. Tristán Hernández, L. J. Ontañón-García

Chaos is often described as the limited development of nonlinear dynamic systems that create intricate and non-repetitive patterns. In this study, we questioned how chaotic electronic signals can be transformed into sound stimuli and explored their impact on brain activity using Electroencephalography (EEG). Our experiment involved 31 participants exposed to sounds generated from three processes from electronic implementations: signals from chaotic attractors, periodic limit cycles,and aleatory distributions. Our goal was to analyze characteristics and EEG signals to uncover the complex relationship between chaotic auditory stimuli and cognitive processes. Interestingly the chaotic stimuli caused a reduction in synchronization in the delta ((delta)) and theta ((theta)) frequency bands. We observed differences of up to 30 and 40%, primarily concentrated in the brain’s frontal areas. This desynchronization in (delta) and (theta) bands, seen in individuals, has implications for regulating irregular (theta) power in certain neural disorders. On the other hand, exposure to signals had mostly minimal effects on EEG readings. This research significantly contributes to our understanding of how the brain responds to stimuli derived from electronic systems. It sheds light on applications for modulating activity. Examining unpredictable sounds offers an understanding of the unique impacts of chaotic auditory inputs on brain activity, opening possibilities for further investigations at the crossroads of chaos theory, acoustics, and neuroscience.

混沌通常被描述为非线性动态系统的有限发展,它能创造出错综复杂且不重复的模式。在这项研究中,我们探讨了如何将混沌电子信号转化为声音刺激,并利用脑电图(EEG)探索其对大脑活动的影响。我们的实验有 31 名参与者参与,他们暴露在由三种电子实现过程产生的声音中:混沌吸引子信号、周期性极限循环信号和任意分布信号。我们的目标是分析特征和脑电图信号,揭示混沌听觉刺激与认知过程之间的复杂关系。有趣的是,混沌刺激会导致delta((delta))和theta((theta))频段的同步性降低。我们观察到的差异高达30%和40%,主要集中在大脑的额叶区域。这种在个体中出现的θ和θ频段的不同步现象,对于调节某些神经失调的不规则θ功率具有重要意义。另一方面,暴露于信号对脑电图读数的影响很小。这项研究极大地促进了我们对大脑如何对来自电子系统的刺激做出反应的理解。它为调节活动的应用提供了启示。通过研究不可预测的声音,我们可以了解混沌听觉输入对大脑活动的独特影响,为在混沌理论、声学和神经科学的交叉领域开展进一步研究提供了可能性。
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引用次数: 0
EEG-based schizophrenia detection using fusion of effective connectivity maps and convolutional neural networks with transfer learning 利用有效连接图和卷积神经网络与迁移学习的融合进行基于脑电图的精神分裂症检测
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-09 DOI: 10.1007/s11571-024-10121-0
Sara Bagherzadeh, Ahmad Shalbaf

Schizophrenia (SZ) is a serious mental disorder that can mainly be distinguished by symptoms including delusions and hallucinations. This mental disorder makes difficult conditions for the person and her/his relatives. Electroencephalogram (EEG) signal is a sophisticated neuroimaging technique that helps neurologists to diagnose this mental disorder. Estimating and evaluating brain effective connectivity between electrode pairs is an appropriate way of diagnosing brain states in neuroscience studies. In this study, we construct a novel image from multi-channels of EEG based on the fusion of three effective connectivity, partial directed coherence (PDC), and direct directed transfer function (dDTF) and transfer entropy (TE) at three consecutive time windows. Then, this image was used as input of five well-known convolutional neural networks (CNNs) through transfer learning (TL) to learn patterns related to SZ patients to diagnose this disorder from normal participants from two public databases. Also, the majority voting method was used to improve these results based on ensemble results of the five CNNs, i.e., ResNet-50, Inception-v3, DenseNet-201, EfficientNetB0, and NasNet-Mobile. The highest average accuracy, specificity and sensitivity to diagnose SZ patients from healthy participants were obtained using EfficientNetB0 through the Leave-One-Subject-out (LOSO) Cross-Validation criterion equal to 96.67%, 96.23%, 96.82%, 95.15%, 94.42% and 96.28% for the first and second databases, respectively. Also, as we suggested, the ensemble approach of EfficientNetB0, ResNet-50 and NasNet-Mobile increased the accuracy by approximately 3%. Our results show the effectiveness of providing fused images from multichannel EEG signals to the ensemble of CNNs through TL to diagnose SZ than state-of-the-art studies.

精神分裂症(SZ)是一种严重的精神障碍,主要表现为妄想和幻觉。这种精神障碍会给患者及其亲属带来困难。脑电图(EEG)信号是一种复杂的神经成像技术,有助于神经学家诊断这种精神障碍。在神经科学研究中,估计和评估电极对之间的大脑有效连接性是诊断大脑状态的适当方法。在本研究中,我们根据三个连续时间窗口的三种有效连通性、部分定向相干性(PDC)、直接定向传递函数(dDTF)和传递熵(TE)的融合,从多通道脑电图中构建了一种新的图像。然后,将该图像作为五个著名卷积神经网络(CNN)的输入,通过迁移学习(TL)学习与 SZ 患者相关的模式,从而从两个公共数据库中的正常参与者中诊断出这种疾病。此外,还使用了多数投票法,根据五个卷积神经网络(即 ResNet-50、Inception-v3、DenseNet-201、EfficientNetB0 和 NasNet-Mobile)的集合结果来改进这些结果。在第一和第二个数据库中,使用 EfficientNetB0 通过留出一个受试者(LOSO)交叉验证标准获得了从健康参与者中诊断出 SZ 患者的最高平均准确率、特异性和灵敏度,分别为 96.67%、96.23%、96.82%、95.15%、94.42% 和 96.28%。此外,正如我们所建议的,EfficientNetB0、ResNet-50 和 NasNet-Mobile 的集合方法将准确率提高了约 3%。我们的研究结果表明,与最先进的研究相比,通过 TL 向 CNN 集合提供多通道脑电信号的融合图像诊断 SZ 更为有效。
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引用次数: 0
Research progress of epileptic seizure prediction methods based on EEG 基于脑电图的癫痫发作预测方法研究进展
IF 3.7 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2024-05-07 DOI: 10.1007/s11571-024-10109-w
Zhongpeng Wang, Xiaoxin Song, Long Chen, Jinxiang Nan, Yulin Sun, Meijun Pang, Kuo Zhang, Xiuyun Liu, Dong Ming

At present, at least 30% of refractory epilepsy patients in the world cannot be effectively controlled and treated. The suddenness and unpredictability of seizures greatly affect the physical and mental health and even the life safety of patients, and the realization of early prediction of seizures and the adoption of interventions are of great significance to the improvement of patients’ quality of life. In this paper, we firstly introduce the design process of EEG-based seizure prediction methods, introduce several databases commonly used in the research, and summarize the commonly used methods in pre-processing, feature extraction, classification and identification, and post-processing. Then, based on scalp EEG and intracranial EEG respectively, we reviewed the current status of epileptic seizure prediction research from five commonly used feature analysis methods, and make a comprehensive evaluation of both. Finally, this paper describes the reasons why the current algorithms cannot be applied to the clinic, summarizes their limitations, and gives corresponding suggestions, aiming to provide improvement directions for subsequent research. In addition, deep learning algorithms have emerged in recent years, and this paper also compares the advantages and disadvantages of deep learning algorithms with traditional machine learning methods, in the hope of providing researchers with new technologies and new ideas and making significant breakthroughs in the field of epileptic seizure prediction.

目前,全球至少有30%的难治性癫痫患者无法得到有效控制和治疗。癫痫发作的突发性和不可预测性极大地影响了患者的身心健康甚至生命安全,实现癫痫发作的早期预测并采取干预措施对提高患者的生活质量具有重要意义。本文首先介绍了基于脑电图的癫痫发作预测方法的设计过程,介绍了研究中常用的几种数据库,总结了预处理、特征提取、分类识别、后处理等方面的常用方法。然后,分别基于头皮脑电图和颅内脑电图,从五种常用的特征分析方法出发,综述了癫痫发作预测研究的现状,并对二者进行了综合评价。最后,本文阐述了当前算法无法应用于临床的原因,总结了其局限性,并给出了相应的建议,旨在为后续研究提供改进方向。此外,近年来出现了深度学习算法,本文也比较了深度学习算法与传统机器学习方法的优缺点,希望能为研究者提供新技术、新思路,在癫痫发作预测领域取得重大突破。
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Cognitive Neurodynamics
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