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Fluoride and Neurodevelopmental Hazard Modelling: An Assessment of Concentration-Response Analysis 氟化物和神经发育危害模型:浓度-反应分析的评估。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-31 DOI: 10.1111/cdoe.70027
Jayanth V. Kumar, Mark E. Moss, Honghu Liu, Susan Fisher-Owens, Andrew Rugg-Gunn, Julia Kuring

Objectives

A National Academies Consensus Study report concluded that the evidence did not support an assessment that fluoride is a neurodevelopmental hazard. However, some researchers have undertaken benchmark dose modelling to determine a safe fluoride concentration level in water. Therefore, the suitability of the data for modelling fluoride concentration in urine and water and cognition response using standard criteria was assessed.

Methods

Data quality was evaluated using a standard tool. A random-effects meta-analysis of standardised mean difference (SMD) and regression coefficients was conducted to assess effect sizes and heterogeneity. The Environmental Protection Agency (EPA) benchmark dose modelling was utilised to determine the association between fluoride concentrations and cognition scores.

Results

All four maternal urinary fluoride (MUF) studies did not meet the standards for acceptable quality, as identified by the EPA data quality criteria, which are necessary for combining data from different studies for dose–response analysis. The pooled estimate was not statistically significant (βMUF = −1.06, 95% CI: −3.63, 1.50; p = 0.42; I2 = 62%). A meta-analysis of five studies conducted in fluoridated areas showed a pooled SMD effect size of 0.04 (95% CI: −0.06, 0.14; p = 0.42; I2 = 0%), favoring higher fluoride. The benchmark dose models did not reveal a functional relationship between MUF or water fluoride concentration and cognitive outcomes (Goodness-of-fit p < 0.1).

Conclusions

The data quality assessment revealed serious flaws that render the maternal urinary studies unacceptable for hazard assessment and benchmark dose modelling. Therefore, more appropriate studies in endemic fluorosis areas are needed to accurately determine whether fluoride is associated with adverse cognitive outcomes in populations with meaningful exposure.

目的:美国国家科学院共识研究报告得出结论,证据不支持氟化物是神经发育危害的评估。然而,一些研究人员进行了基准剂量模拟,以确定水中的安全氟化物浓度水平。因此,评估了使用标准标准模拟尿液和水中氟化物浓度以及认知反应的数据的适用性。方法:采用标准工具评价资料质量。对标准化平均差(SMD)和回归系数进行随机效应荟萃分析,以评估效应大小和异质性。环境保护署(EPA)的基准剂量模型被用来确定氟化物浓度和认知评分之间的关系。结果:所有四项产妇尿氟化物(MUF)研究均未达到EPA数据质量标准所确定的可接受质量标准,这是将不同研究的数据合并进行剂量-反应分析所必需的。合并估计无统计学意义(βMUF = -1.06, 95% CI: -3.63, 1.50; p = 0.42; I2 = 62%)。在加氟地区进行的五项研究的荟萃分析显示,合并SMD效应大小为0.04 (95% CI: -0.06, 0.14; p = 0.42; I2 = 0%),有利于较高的氟化物。基准剂量模型没有揭示MUF或水中氟化物浓度与认知结果之间的函数关系(拟合质量p)结论:数据质量评估揭示了严重的缺陷,使得母体尿液研究无法用于危害评估和基准剂量模型。因此,需要在地方性氟中毒地区进行更适当的研究,以准确确定氟化物是否与有意义接触人群的不良认知结果有关。
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引用次数: 0
The Role of Health Literacy in Adults' Dental Service Utilisation: A Scoping Review. 健康素养在成人牙科服务利用中的作用:范围审查。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-30 DOI: 10.1111/cdoe.70037
Xuanyun Lu, Sucharita Nanjappa, Thushani Indumani Devi Wijesiri, Peter Mossey, Siyang Yuan

Objectives: Health literacy refers to an individual's ability to understand health information, navigate healthcare systems, make informed decisions and adopt health-promoting behaviours. The scoping review examined the available literature to explore adults' health literacy levels, health literacy measurements, and the role of health literacy in adults' dental service utilisation.

Methods: The scoping review used Arksey and O'Malley's framework, refined by Joanna Briggs Institute methodology. The inclusion criteria were peer-reviewed studies, published in English with adult participants in a dental setting. Four databases (MEDLINE via PubMed, Scopus, CINAHL and ASSIA) were searched for relevant studies from January 2000 to January 2025.

Results: Nineteen studies met the inclusion criteria, with 12 out of 19 conducted in the US. Health literacy was assessed by 11 different measures. Although most studies reported relatively inadequate health literacy levels, inconsistent findings persist due to a lack of consensus on measurement. Dental service utilisation, primarily assessed by dental visits, dental information seeking, and dentist-patient communication, demonstrated inconsistent associations with health literacy.

Conclusions: While some studies suggested a positive association between health literacy and dental service utilisation, the mechanisms through which health literacy influenced dental service utilisation remained unclear and required further investigation.

目标:卫生素养是指个人理解卫生信息、驾驭卫生保健系统、做出知情决定和采取促进健康行为的能力。范围审查检查了现有文献,以探讨成人健康素养水平,健康素养测量,以及健康素养在成人牙科服务利用中的作用。方法:范围审查使用Arksey和O'Malley的框架,由乔安娜布里格斯研究所的方法改进。纳入标准是同行评议的研究,发表在英语与成人参与者在牙科设置。检索了四个数据库(MEDLINE via PubMed, Scopus, CINAHL和ASSIA)从2000年1月到2025年1月的相关研究。结果:19项研究符合纳入标准,19项研究中有12项在美国进行。通过11项不同措施评估了卫生素养。虽然大多数研究报告了相对不足的卫生素养水平,但由于在测量上缺乏共识,不一致的结果仍然存在。牙科服务的利用,主要通过牙科就诊、牙科信息寻求和牙医-患者沟通来评估,显示出与健康素养不一致的关联。结论:虽然一些研究表明健康素养与牙科服务利用之间存在正相关关系,但健康素养影响牙科服务利用的机制仍不清楚,需要进一步调查。
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引用次数: 0
Oral Health and Social Isolation After 6 Years: Mediation of Oral Functions. 口腔健康与6年后的社会隔离:口腔功能的中介作用。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-26 DOI: 10.1111/cdoe.70035
Hazem Abbas, Kenji Takeuchi, Taro Kusama, Sakura Kiuchi, Ken Osaka

Objectives: Tooth loss was longitudinally associated with social isolation. The absence of dental prosthesis use was an additional risk factor. However, the mediating pathways for this association are unknown. The aim of this cohort study was to estimate the mediating effect of three oral functions: speaking, smiling and chewing observed at baseline on the association between oral health at baseline and social isolation after 6 years of follow-up.

Methods: The 2010-2016 panel data from 6103 functionally independent participants aged ≥ 65 years who were not socially isolated at baseline was used from the Japan Gerontological Evaluation Study (JAGES). Causal mediation analysis using parametric logistic regression models was used to calculate the natural direct effect (NDE), the natural indirect effect (NIE), and the total effect. Social isolation was derived from a 5-point index and dichotomised (0/3 = not isolated, 4/5 = isolated). The confounders observed at baseline were age, sex, educational attainment, income, activities of daily living, living area, and having depressive symptoms assessed using the geriatric depression scale (GDS-15).

Results: The mean age of the participants was 72.4 years (SD = ±5.1), and 44.7% were males. Social isolation was observed at follow-up among 3.6% of participants (n = 220). The cumulative incidence rate of socially isolated participants among those with ≥ 20 teeth was 2.9% increasing gradually to 3.2%, 3.5%, 3.7% and 7.2% among those with 10-19 teeth and used dental prosthesis, 10-19 teeth and did not use the dental prosthesis, 0-9 teeth and used dental prosthesis, and 0-9 teeth and did not use the dental prosthesis respectively. Compared with those with ≥ 20 teeth, having difficulty in speaking [NIE odds ratio (OR) = 1.02, 95% confidence interval (CI) = 0.93-1.11], problems in smiling (NIE OR = 1.02, 95% CI = 0.93-1.10) and difficulty in chewing (NIE OR = 1.04, 95% CI = 0.94-1.14) might have mediated the association for those with 10-19 teeth and used dental prosthesis as well as for those with 10-19 teeth without dental prosthesis (NIE OR = 1.02, 95% CI = 0.94-1.10), (NIE OR = 1.02, 95% CI = 0.93-1.11) and (NIE OR = 1.02, 95% CI = 0.93-1.11) respectively. While they might not have mediated the association for those with 0-9 teeth with and without dental prosthesis use.

Conclusion: With low precision and uncertain estimates, limited oral function might have mediated the association between tooth loss (10-19 with and without dental prosthesis use groups) and social isolation over 6 years. It was uncertain whether a mediation effect of oral functions was observed for those with 0-9 teeth with and without dental prosthesis use.

目的:牙齿脱落在纵向上与社会隔离有关。没有使用义齿是另一个危险因素。然而,这种关联的介导途径尚不清楚。本队列研究的目的是在6年随访后,估计基线时观察到的三种口腔功能:说话、微笑和咀嚼在基线口腔健康与社会孤立之间的中介作用。方法:2010-2016年的面板数据来自日本老年学评估研究(JAGES),来自6103名≥65岁的功能独立参与者,他们在基线时未被社会隔离。采用参数logistic回归模型进行因果中介分析,计算自然直接效应(NDE)、自然间接效应(NIE)和总效应。社会隔离由5点指数得出,并进行了二分类(0/3 =未隔离,4/5 =隔离)。基线时观察到的混杂因素包括年龄、性别、受教育程度、收入、日常生活活动、居住面积,以及使用老年抑郁量表(GDS-15)评估抑郁症状。结果:参与者平均年龄为72.4岁(SD =±5.1),男性占44.7%。在随访中,3.6%的参与者(n = 220)被观察到社会隔离。≥20颗牙的社会隔离患者累计发病率为2.9%,10-19颗牙使用义齿、10-19颗牙未使用义齿、0-9颗牙使用义齿和0-9颗牙未使用义齿者的累计发病率分别为3.2%、3.5%、3.7%和7.2%。与≥20组相比牙齿,说话有困难(NIE比值比(或)= 1.02,95%可信区间(CI) = 0.93 - -1.11),问题微笑(NIE或= 1.02,95% CI = 0.93 - -1.10)和咀嚼困难(NIE或= 1.04,95% CI = 0.94 - -1.14)可能介导协会10 - 19的牙齿和牙齿假肢以及用于那些10 - 19的牙齿没有牙科假肢(NIE或= 1.02,95% CI -1.10 = 0.94), (NIE或= 1.02,NIE CI = 0.93 - -1.11)和95%(或= 1.02,95% CI = 0.93 - -1.11)。虽然他们可能没有调解那些0-9颗牙齿的人是否使用假牙。结论:在低精度和不确定的估计下,有限的口腔功能可能介导了6年来牙齿脱落(10-19名使用和不使用义齿的人群)与社会隔离之间的关联。对于0 ~ 9牙的患者,使用和不使用义齿是否存在口腔功能的中介作用尚不确定。
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引用次数: 0
Tracking the Debate: Geo-Temporal Sentiment Analysis of Community Water Fluoridation on 'X' (Formerly Twitter) With Five-Year Forecast. 追踪辩论:“X”(以前的Twitter)上社区水氟化的地理-时间情感分析与五年预测。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-23 DOI: 10.1111/cdoe.70036
Nilesh Torwane, Ratilal Lalloo, Diep Ha, Loc Do

Objectives: This study examined country-level geo-temporal sentiment trends in community water fluoridation (CWF) discussions on 'X' from 2014 to 2023 and generated a five-year forecast to anticipate future shifts.

Methods: Sentiment analysis was conducted using the VADER 'SentimentIntensityAnalyzer', with polarity thresholds defined as negative (< -0.05), neutral (-0.05 to +0.05) and positive (> +0.05). Data were collected via the 'X' API and examined for sentiment distribution, country-level geo-temporal patterns based on user location information, and engagement metrics (likes, retweets, replies). Ethical approval was obtained, and only publicly available data were analysed in compliance with the platform's terms of service. Limitations include restriction to English-language tweets and the non-representativeness and demographic biases of 'X' users compared with national populations.

Results: Of 72 309 original tweets analysed, 37.4% were negative, 34.4% positive and 28.2% neutral. Countries with low tweet volumes (e.g., Venezuela, Cyprus, Croatia, Pakistan, Vietnam) showed predominantly positive sentiment. In contrast, high-volume countries (the US, Canada, Australia, Brazil and the United Kingdom) displayed mixed sentiment without a clear majority. Predictive modelling indicated a modest shift toward less positive sentiment polarity over the next 5 years, with average polarity projected to decrease from 0.43 in 2024 to 0.38 in 2028. Supplementary analysis of more recent tweets (Jan 2024-Aug 2025) provided further insight into emerging patterns, broadly consistent with the projected trends.

Conclusions: CWF discourse on 'X' is polarised and varies across countries and time. The expected decline in positivity underscores the need for tailored country-specific public health communication strategies to strengthen engagement and counter misinformation.

目的:本研究调查了2014年至2023年社区水氟化(CWF)关于“X”讨论的国家级地理时间情绪趋势,并生成了一个五年预测,以预测未来的变化。方法:使用VADER ‘SentimentIntensityAnalyzer’进行情绪分析,极性阈值定义为负(+0.05)。数据通过“X”API收集,并检查情绪分布、基于用户位置信息的国家级地理时间模式和参与指标(喜欢、转发、回复)。获得了道德批准,并且仅根据平台的服务条款分析了公开可用的数据。局限性包括对英语推文的限制,以及与国家人口相比,“X”用户的非代表性和人口统计学偏差。结果:在分析的72 309条原创推文中,37.4%为负面,34.4%为正面,28.2%为中性。推特数量较少的国家(如委内瑞拉、塞浦路斯、克罗地亚、巴基斯坦、越南)主要表现出积极的情绪。相比之下,交易量大的国家(美国、加拿大、澳大利亚、巴西和英国)表现出复杂的情绪,但没有明显的多数。预测模型显示,未来5年情绪极性将向不那么积极的方向适度转变,平均极性预计将从2024年的0.43降至2028年的0.38。对近期推文(2024年1月至2025年8月)的补充分析提供了对新兴模式的进一步洞察,与预测趋势大致一致。结论:CWF关于“X”的论述是两极分化的,并且在不同的国家和时间有所不同。预期的积极性下降突出表明,需要制定针对具体国家的公共卫生传播战略,以加强参与和打击错误信息。
{"title":"Tracking the Debate: Geo-Temporal Sentiment Analysis of Community Water Fluoridation on 'X' (Formerly Twitter) With Five-Year Forecast.","authors":"Nilesh Torwane, Ratilal Lalloo, Diep Ha, Loc Do","doi":"10.1111/cdoe.70036","DOIUrl":"https://doi.org/10.1111/cdoe.70036","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined country-level geo-temporal sentiment trends in community water fluoridation (CWF) discussions on 'X' from 2014 to 2023 and generated a five-year forecast to anticipate future shifts.</p><p><strong>Methods: </strong>Sentiment analysis was conducted using the VADER 'SentimentIntensityAnalyzer', with polarity thresholds defined as negative (< -0.05), neutral (-0.05 to +0.05) and positive (> +0.05). Data were collected via the 'X' API and examined for sentiment distribution, country-level geo-temporal patterns based on user location information, and engagement metrics (likes, retweets, replies). Ethical approval was obtained, and only publicly available data were analysed in compliance with the platform's terms of service. Limitations include restriction to English-language tweets and the non-representativeness and demographic biases of 'X' users compared with national populations.</p><p><strong>Results: </strong>Of 72 309 original tweets analysed, 37.4% were negative, 34.4% positive and 28.2% neutral. Countries with low tweet volumes (e.g., Venezuela, Cyprus, Croatia, Pakistan, Vietnam) showed predominantly positive sentiment. In contrast, high-volume countries (the US, Canada, Australia, Brazil and the United Kingdom) displayed mixed sentiment without a clear majority. Predictive modelling indicated a modest shift toward less positive sentiment polarity over the next 5 years, with average polarity projected to decrease from 0.43 in 2024 to 0.38 in 2028. Supplementary analysis of more recent tweets (Jan 2024-Aug 2025) provided further insight into emerging patterns, broadly consistent with the projected trends.</p><p><strong>Conclusions: </strong>CWF discourse on 'X' is polarised and varies across countries and time. The expected decline in positivity underscores the need for tailored country-specific public health communication strategies to strengthen engagement and counter misinformation.</p>","PeriodicalId":10580,"journal":{"name":"Community dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145353974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sense of Coherence as a Modifier of Income Inequalities in Self-Rated Oral and General Health: A Cross-Sectional Study. 连贯感作为自评口腔健康和一般健康收入不平等的调节因素:一项横断面研究。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-21 DOI: 10.1111/cdoe.70033
Mehrsa Zakershahrak, Sergio Chrisopoulos, Liana Luzzi, Lisa Jamieson, David Brennan

Objective: To investigate whether a stronger Sense of Coherence (SOC) modifies the association between low household income and poor self-rated dental and general health measures (SRDH and SRGH, respectively).

Methods: Cross-sectional analyses were performed using data from the Dental Care and Oral Health Study (DCOHS, 2015-2016) in South Australia (n = 3664). In multivariate Poisson regression models, the main effects, interactions and effect modifications of SOC in the association between income and SRDH and SRGH were estimated using prevalence ratios (PRs) for poor self-rated health.

Results: In the low-income group, among those with stronger SOC, the prevalence of poor SRDH (16.0%) and SRGH (8.1%) was lower than that of those with weaker SOC (25.0% and 18.9%). Lower coherence (weak SOC) was associated with poor SRGH (PR = 4.8, 95% CI [1.8-13.1]). The interaction between lower coherence and low- and middle-income strata was not associated with the prevalence of poor SRDH and SRGH.

Conclusions: Although interactions between SOC and income were not statistically significant, findings suggest a potential modifying role of strong SOC on the association between low income and poor health. These results should be interpreted with caution, as they are exploratory.

目的:探讨较强的连贯性意识(SOC)是否改变了低收入家庭收入与不良口腔健康和一般健康指标(分别为SRDH和SRGH)之间的关系。方法:采用南澳牙科保健和口腔健康研究(DCOHS, 2015-2016)的数据进行横断面分析(n = 3664)。在多元泊松回归模型中,利用自评健康状况不佳的患病率(pr)估算了SOC在收入与SRDH和SRGH相关性中的主要作用、相互作用和作用变化。结果:在低收入人群中,SOC较强的人群中,不良SRDH患病率(16.0%)和SRGH患病率(8.1%)低于SOC较弱的人群(25.0%和18.9%)。连贯性较低(SOC较弱)与SRGH较差相关(PR = 4.8, 95% CI[1.8-13.1])。低一致性与中低收入阶层之间的相互作用与低SRDH和SRGH的患病率无关。结论:虽然SOC与收入之间的相互作用没有统计学意义,但研究结果表明,高SOC对低收入与健康状况不佳之间的关联具有潜在的调节作用。这些结果应该谨慎解释,因为它们是探索性的。
{"title":"Sense of Coherence as a Modifier of Income Inequalities in Self-Rated Oral and General Health: A Cross-Sectional Study.","authors":"Mehrsa Zakershahrak, Sergio Chrisopoulos, Liana Luzzi, Lisa Jamieson, David Brennan","doi":"10.1111/cdoe.70033","DOIUrl":"https://doi.org/10.1111/cdoe.70033","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether a stronger Sense of Coherence (SOC) modifies the association between low household income and poor self-rated dental and general health measures (SRDH and SRGH, respectively).</p><p><strong>Methods: </strong>Cross-sectional analyses were performed using data from the Dental Care and Oral Health Study (DCOHS, 2015-2016) in South Australia (n = 3664). In multivariate Poisson regression models, the main effects, interactions and effect modifications of SOC in the association between income and SRDH and SRGH were estimated using prevalence ratios (PRs) for poor self-rated health.</p><p><strong>Results: </strong>In the low-income group, among those with stronger SOC, the prevalence of poor SRDH (16.0%) and SRGH (8.1%) was lower than that of those with weaker SOC (25.0% and 18.9%). Lower coherence (weak SOC) was associated with poor SRGH (PR = 4.8, 95% CI [1.8-13.1]). The interaction between lower coherence and low- and middle-income strata was not associated with the prevalence of poor SRDH and SRGH.</p><p><strong>Conclusions: </strong>Although interactions between SOC and income were not statistically significant, findings suggest a potential modifying role of strong SOC on the association between low income and poor health. These results should be interpreted with caution, as they are exploratory.</p>","PeriodicalId":10580,"journal":{"name":"Community dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145343951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends of Dispensed Opioids Prescribed by Australian Dentists: 2013–2022 澳大利亚牙医处方阿片类药物的趋势:2013-2022。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-07 DOI: 10.1111/cdoe.70022
Leanne Teoh, Marietta Taylor, Erin Kelty, Frank M. Sanfilippo, Mathew Lim, Michael McCullough, Christopher Etherton-Beer, Alex Park, David Preen, Amy Page

Background

In Australia, the prescribing of opioid medicines by dentists has increased in recent years, despite opioids not being first-line treatment for dental pain. The aim of this longitudinal study was to examine the dispensing of opioids prescribed by dentists in Australia during 2013–2022.

Method

A nationally representative 10% sample of patients identified from the Australian Pharmaceutical Benefits Scheme dispensing data from 2013 to 2022 was used. Three outcomes were assessed: (1) incidence of dispensing of all dental prescriptions; (2) incidence of dispensing of opioids prescribed by dentists; (3) average number of tablets/capsules of dental opioid supply. Outcomes pertaining to opioid use were examined overall, and by year, age and sex.

Results

From 2013 to 2022, 998 774 dental prescriptions (of any kind) were dispensed to 470 118 patients. The mean annual incidence rate for dispensing any dental medication was 48.4 (95% CI: 48.3–48.5)/1000 person-years. Opioids accounted for 183 303 prescriptions (18.4%), with a mean annual incidence rate of 11.0 (95% CI: 11.0–11.1)/1000 person-years. The majority of patients (99.1%) were dispensed ≤ 4 opioid prescriptions across the 10-year period, with 0.9% of patients (n = 1312) receiving between 5 and 149 dispensed opioids. Over the study period, the average annual incidence of dispensed dental opioids increased by 4.4% (95% CI: 1.0–8.2). A reduction in the mean quantity of opioid pills dispensed was observed over time. Dental opioids were dispensed to 2727 children and adolescents.

Conclusion

The incidence of dispensing of dental opioids in Australia increased by an average of 4.4% per year over a decade. While there was a reduction in opioid quantities dispensed, dispensing of opioids for children occurred, and a small number of patients were dispensed excessive quantities of dental opioids. Evidence-based tailored opioid stewardship interventions need to include dentists, and dentists should be provided access to drug monitoring programmes to enable more informed prescribing decisions.

背景:在澳大利亚,尽管阿片类药物不是治疗牙痛的一线药物,但近年来牙医开具的阿片类药物处方有所增加。这项纵向研究的目的是检查2013-2022年澳大利亚牙医处方的阿片类药物的分配情况。方法:采用从2013年至2022年澳大利亚药品福利计划调剂数据中确定的具有全国代表性的10%患者样本。评估了三个结果:(1)所有牙科处方的配药率;(2)按牙医处方配发阿片类药物的发生率;(3)牙科阿片类药物平均供应片剂/胶囊数量。与阿片类药物使用有关的结果进行了总体检查,并按年份、年龄和性别进行了检查。结果:2013 - 2022年,共发放各类牙科处方998 774张,惠及470118例患者。配发任何牙科药物的平均年发病率为48.4 (95% CI: 48.3-48.5)/1000人年。阿片类药物占处方183 303张(18.4%),平均年发病率为11.0 (95% CI: 11.0-11.1)/1000人年。大多数患者(99.1%)在10年期间获得了≤4张阿片类药物处方,0.9%的患者(n = 1312)获得了5至149张阿片类药物处方。在研究期间,牙科阿片类药物的平均年发病率增加了4.4% (95% CI: 1.0-8.2)。随着时间的推移,观察到阿片类药物的平均配药量减少。为2727名儿童和青少年配发了牙科阿片类药物。结论:十年来,澳大利亚牙科阿片类药物配药的发生率平均每年增加4.4%。虽然发放的阿片类药物数量有所减少,但仍发生了为儿童发放阿片类药物的情况,少数患者被发放了过量的牙科阿片类药物。基于证据的量身定制的阿片类药物管理干预措施需要包括牙医,并应向牙医提供药物监测规划,以使他们能够做出更明智的处方决策。
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引用次数: 0
Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study. 为患有罕见疾病的儿童和青少年绘制牙科保健地图:一项巴西多中心研究。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-03 DOI: 10.1111/cdoe.70029
Heloisa Vieira Prado, Rayssa Maria Soalheiro de Souza, Gabriella Guerra Freire Gabrich Fonseca, Kamila Rodrigues Junqueira Carvalho, Anna Vitória Mendes Viana Silva, Iasmin Fonseca Tolentino Mascarenhas, Beatriz Rezende Bergo, Hanna Larissa Barbosa Soares, Bárbara Mendes de Jesus, Layanne Ribeiro Ferreira E Sobral, Kélisson Duarte Reis, Késia Lara Dos Santos Marques, Fabiana Sodré de Oliveira, Daniella Reis Barbosa Martelli, José Alcides Almeida de Arruda, Benjamin P J Fournier, Denise Vieira Travassos, Soraia Macari, Célia Regina Moreira Lanza, Ana Cristina Borges-Oliveira, Hercílio Martelli-Júnior, Tarcília Aparecida Silva

Objectives: To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil.

Methods: A retrospective cross-sectional study was conducted involving individuals aged 0-18 years with a confirmed diagnosis of a RD who received care at five specialised dental centres. Data on the diagnosis, age at first dental appointment, frequency of annual visits and travel distance from home to treatment centre were analysed using descriptive and inferential statistics.

Results: A total of 1057 individuals with 244 different RDs were identified. Most were boys (54.9%). The average age at the first dental appointment was 8.52 years. Haematological diseases were the most prevalent (38.9%). The average travel distance for treatment was 99.1 km, with individuals from the Jequitinhonha region traveling the farthest (526.3 km). The average number of annual dental visits was 2.4. Patients with craniofacial syndromes accessed care earlier (average: 3.6 years) and had more frequent follow-up appointments (average: 4.8 visits/year). Significant regional disparities were found in age at first appointment (p < 0.001), travel distance (p < 0.001) and frequency of visits (p = 0.002).

Conclusions: Children and adolescents with RDs had delayed initiation of dental care, low follow-up rates and substantial travel burdens. The concentration of specialised centres in the state capital underscores the need for policy reforms to improve equitable access, particularly for patients in remote areas.

目的:描述巴西东南部米纳斯吉拉斯州患有罕见疾病(rd)的儿童和青少年专门中心提供的牙科保健情况。方法:回顾性横断面研究涉及年龄0-18岁,确诊为RD并在5个专业牙科中心接受治疗的个体。使用描述性和推断性统计分析诊断、首次牙科预约年龄、年度就诊频率和从家到治疗中心的旅行距离等数据。结果:共鉴定出244个不同rd的1057个个体。大多数是男孩(54.9%)。首次看牙医的平均年龄为8.52岁。血液病最为常见(38.9%)。平均旅行距离为99.1 km,其中Jequitinhonha地区的个体旅行距离最远(526.3 km)。平均每年看牙医2.4次。颅面综合征患者获得护理的时间较早(平均3.6年),随访次数较多(平均4.8次/年)。在首次就诊年龄方面存在显著的地区差异(p)。结论:患有rd的儿童和青少年开始牙科保健的时间较晚,随访率低,旅行负担大。专科中心集中在邦首府,这凸显了政策改革的必要性,以改善公平准入,特别是对偏远地区的患者。
{"title":"Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study.","authors":"Heloisa Vieira Prado, Rayssa Maria Soalheiro de Souza, Gabriella Guerra Freire Gabrich Fonseca, Kamila Rodrigues Junqueira Carvalho, Anna Vitória Mendes Viana Silva, Iasmin Fonseca Tolentino Mascarenhas, Beatriz Rezende Bergo, Hanna Larissa Barbosa Soares, Bárbara Mendes de Jesus, Layanne Ribeiro Ferreira E Sobral, Kélisson Duarte Reis, Késia Lara Dos Santos Marques, Fabiana Sodré de Oliveira, Daniella Reis Barbosa Martelli, José Alcides Almeida de Arruda, Benjamin P J Fournier, Denise Vieira Travassos, Soraia Macari, Célia Regina Moreira Lanza, Ana Cristina Borges-Oliveira, Hercílio Martelli-Júnior, Tarcília Aparecida Silva","doi":"10.1111/cdoe.70029","DOIUrl":"https://doi.org/10.1111/cdoe.70029","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted involving individuals aged 0-18 years with a confirmed diagnosis of a RD who received care at five specialised dental centres. Data on the diagnosis, age at first dental appointment, frequency of annual visits and travel distance from home to treatment centre were analysed using descriptive and inferential statistics.</p><p><strong>Results: </strong>A total of 1057 individuals with 244 different RDs were identified. Most were boys (54.9%). The average age at the first dental appointment was 8.52 years. Haematological diseases were the most prevalent (38.9%). The average travel distance for treatment was 99.1 km, with individuals from the Jequitinhonha region traveling the farthest (526.3 km). The average number of annual dental visits was 2.4. Patients with craniofacial syndromes accessed care earlier (average: 3.6 years) and had more frequent follow-up appointments (average: 4.8 visits/year). Significant regional disparities were found in age at first appointment (p < 0.001), travel distance (p < 0.001) and frequency of visits (p = 0.002).</p><p><strong>Conclusions: </strong>Children and adolescents with RDs had delayed initiation of dental care, low follow-up rates and substantial travel burdens. The concentration of specialised centres in the state capital underscores the need for policy reforms to improve equitable access, particularly for patients in remote areas.</p>","PeriodicalId":10580,"journal":{"name":"Community dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceived Barriers and Potential Strategies for People Who Use Drugs in Accessing Oral Healthcare: A Qualitative Study of Service Providers 感知障碍和潜在策略的人使用药物在获得口腔保健:服务提供者的定性研究。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-30 DOI: 10.1111/cdoe.70028
Tejashree Kangutkar, Mark Gussy, Ronald Knevel, Hanny Calache
<div> <section> <h3> Objective</h3> <p>Access to appropriate oral healthcare is vital for overall health and well-being. However, people who use drugs (PWUD) often face significant barriers in accessing oral healthcare services. This qualitative study focused on exploring the perspectives of public oral health service providers and harm reduction workers to understand the barriers that they perceived were experienced by PWUD in accessing oral healthcare and identified potential strategies to address these barriers.</p> </section> <section> <h3> Method</h3> <p>Thirty-five participants (20 public oral health service providers and 15 harm reduction workers) were recruited from both metropolitan and regional areas of Victoria, Australia, through purposive sampling and a snowballing technique. Individual online semi-structured interviews were conducted, and data were analysed using a hybrid approach to thematic analysis.</p> </section> <section> <h3> Results</h3> <p>Service providers felt that continuous drug use impacted PWUD's ability to perceive dental pain, which delayed identification of oral health symptoms at the individual level. Major life crises meant that PWUD had limited awareness about the oral health consequences of their drug use, which further hindered their access to care. Service providers described how negative experiences and perceived judgements by PWUD about the visual effects of drugs created barriers to accessing dental care. Triggers of memories of traumatic abuse associated with the dental environments were also identified as a distressing factor for PWUD. Perceived service-level barriers included the lack of explicit recognition of PWUD as eligible for priority access in public dental clinics, financial impediments and coercive tactics from some oral health service providers. Service providers with experience of working in rural areas shared how the lack of anonymity and the risk of being identified as a drug user was an additional challenge for PWUD in accessing oral health services in rural areas. The participants proposed several potential strategies including drop-in oral health sessions at harm reduction facilities involving case managers to address appointment issues and training oral health service providers in trauma-informed care. They emphasised the need for interprofessional collaboration between oral health and harm reduction sectors. One key recommendation proposed by the participants was to establish oral health integrated harm reduction programmes that require careful consideration of feasibility, acceptability, resource allocation and potential implications on service quality.</p> </section>
目的:获得适当的口腔保健对整体健康和福祉至关重要。然而,吸毒者(PWUD)在获得口腔保健服务方面往往面临重大障碍。本定性研究的重点是探索公共口腔卫生服务提供者和减少伤害工作者的观点,以了解他们认为puwud在获得口腔卫生保健方面遇到的障碍,并确定解决这些障碍的潜在策略。方法:采用有目的抽样和滚雪球法,从澳大利亚维多利亚州市区和郊区招募35名参与者(20名公共口腔卫生服务提供者和15名减少危害工作者)。进行了个人在线半结构化访谈,并使用主题分析的混合方法分析数据。结果:服务提供者认为持续的药物使用影响了puwud感知牙齿疼痛的能力,从而延迟了个体对口腔健康症状的识别。重大的生命危机意味着,吸毒者对吸毒对口腔健康的影响认识有限,这进一步阻碍了他们获得护理。服务提供者描述了PWUD对药物视觉效果的负面体验和感知判断如何对获得牙科护理造成障碍。与牙科环境相关的创伤性虐待记忆的触发也被确定为PWUD的痛苦因素。感知到的服务水平障碍包括没有明确承认puwud有资格优先获得公共牙科诊所的服务,财政障碍和一些口腔保健服务提供者的强制手段。具有在农村地区工作经验的服务提供者表示,缺乏匿名性和被确定为吸毒者的风险是妇女和妇女在农村地区获得口腔保健服务的另一个挑战。与会者提出了几项可能的战略,包括在减少伤害设施举行由病例管理人员参与的临时口腔卫生会议,以解决预约问题,并对口腔卫生服务提供者进行创伤知情护理方面的培训。他们强调需要在口腔卫生和减少危害部门之间进行专业间合作。与会者提出的一项重要建议是制定口腔健康综合减少危害方案,这些方案需要认真考虑可行性、可接受性、资源分配和对服务质量的潜在影响。结论:本研究突出了以前未被认识到的服务提供者与puwud合作的感知障碍,这些障碍可能影响旨在改善puwud获得牙科服务的任何干预措施的实施。通过综合解决个体和服务水平的障碍,卫生保健系统可以更好地满足PWUD的口腔卫生需求,减少获得保健的差距。
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引用次数: 0
Assessing the Impact of Periodontal Therapy on Tooth Loss: A Register-Based Longitudinal Study in Denmark 评估牙周治疗对牙齿脱落的影响:丹麦一项基于注册的纵向研究。
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-26 DOI: 10.1111/cdoe.70026
Eero Raittio, Vibeke Baelum

Objectives

While regular periodontal care is advocated to reduce tooth loss considerably among periodontitis patients, evidence from observational studies is often limited to small single-center studies. This study aims to quantify the effect of periodontal care on tooth extractions among 40-year-old new periodontitis patients over 20 years.

Methods

A nationwide register-based cohort study was conducted, encompassing 40-year-old individuals with incident periodontitis in 2001, tracked through Danish registers until the end of 2021. Receiving any periodontal care was determined annually, and the number of tooth extractions served as the annually varying outcome. G-estimation of structural nested mean models adjusted for time-varying confounding and loss to follow-up was employed to estimate the average treatment effect of periodontal therapy on subsequent tooth extractions.

Results

The study included 1251 40-year-olds with incident periodontitis in 2001. The average follow-up from 2002 onwards was 19.1 years and amounted to 23,878 person-years. On average, participants received periodontal care in 12.1 years (SD 6.3) and lost an average of 2.3 teeth (SD 3.5). G-estimation showed that receiving periodontal therapy in a given year compared to not receiving any periodontal therapy reduced the number of teeth extracted in the following year by 0.04 (95% CI: 0.02; 0.06). Receiving periodontal therapy for 5 years in a row compared to not receiving any periodontal therapy was associated with an average of 0.08 (95% CI: 0.04; 0.13) fewer extracted teeth, while on average 0.62 teeth were lost in a 5-year period (0.12 per year).

Conclusions

Periodontal therapy resulted in a modest reduction in tooth extractions among 40-year-olds with incident periodontitis over 20 years. The effectiveness of periodontal therapy against tooth loss seems to be considerably smaller than indicated by earlier clinical studies.

目的:虽然提倡定期牙周护理以显著减少牙周炎患者的牙齿脱落,但观察性研究的证据通常仅限于小型单中心研究。本研究旨在量化牙周护理对40岁新发牙周炎患者拔牙的影响。方法:在全国范围内进行了一项基于登记的队列研究,纳入了2001年发生牙周炎的40岁个体,通过丹麦登记册追踪到2021年底。每年确定接受任何牙周护理,拔牙次数作为每年变化的结果。采用经时变混杂因素和随访损失调整的结构嵌套均值模型的g估计来估计牙周治疗对后续拔牙的平均治疗效果。结果:该研究包括1251名2001年发生牙周炎的40岁人群。从2002年起的平均随访时间为19.1年,总计23,878人年。参与者平均在12.1年(SD 6.3)内接受牙周护理,平均脱落2.3颗牙齿(SD 3.5)。g -估计显示,与未接受任何牙周治疗的患者相比,在某一年接受牙周治疗的患者在下一年拔牙数量减少了0.04 (95% CI: 0.02; 0.06)。与不接受任何牙周治疗的患者相比,连续5年接受牙周治疗的患者拔牙数量平均减少0.08颗(95% CI: 0.04; 0.13),而5年期间平均脱落0.62颗牙齿(每年0.12颗)。结论:牙周治疗导致40岁的牙周炎患者在20年内拔牙的数量适度减少。牙周治疗对牙齿脱落的效果似乎比早期临床研究表明的要小得多。
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引用次数: 0
Oral Health Outcomes and Their Sociodemographic and Service Utilisation Determinants in a Rural Population 农村人口口腔健康结果及其社会人口统计学和服务利用决定因素
IF 2.1 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-25 DOI: 10.1111/cdoe.70024
Mariana Silveira Echeverria, Rafaela do Carmo Borges, Sarah Arangurem Karam, Gabrielle Haubert, Mariana Gonzalez Cademartori, Bernardo Antonio Agostini, Flávio Fernando Demarco

Objectives

The aim of the study was to evaluate the number of remaining teeth, use of dental prosthesis, and self-perception of oral health according to sociodemographic variables and use of dental services in a rural population of the Municipality of Pelotas, RS, through a cross-sectional population-based study.

Methods

A cross-sectional study was conducted in the rural area of Pelotas, Brazil, aiming to assess the oral health status of adults aged 18 or older. Data collection occurred through a systematic sampling process in two stages, with sociodemographic factors and oral health outcomes analysed. The number of remaining teeth, use of dental prosthesis, self-perception of oral health and dental visit patterns were among the variables examined. Prevalence ratios were estimated using Poisson regression and odds ratios were estimated using ordinal logistic regression.

Results

Out of 1519 adults surveyed, the majority were male, aged 40–59, and had incomplete elementary education. Elderly women and people in the richest income quintile exhibited lower rates of remaining teeth and higher use of prosthesis, while people with higher education and use of dental services in the last year had more teeth. Worse self-perception of oral health was more prevalent in men, at age 40–59 and who had used dental services for curative reasons.

Conclusions

The study highlights the need for targeted interventions to address oral health disparities in rural areas, emphasising the importance of preventive measures and equitable access to dental services. Strategies focusing on increasing access and reducing financial barriers can contribute to improving oral health outcomes among rural populations.

目的:本研究的目的是通过一项基于人口的横断面研究,根据社会人口统计学变量和RS Pelotas市农村人口的牙科服务使用情况,评估剩余牙齿的数量、义齿的使用情况和口腔健康的自我认知。方法:在巴西佩洛塔斯农村地区进行了一项横断面研究,旨在评估18岁及以上成年人的口腔健康状况。通过两个阶段的系统抽样过程收集数据,并分析了社会人口因素和口腔健康结果。调查的变量包括剩余牙齿的数量、义齿的使用、口腔健康的自我认知和牙科就诊模式。使用泊松回归估计患病率,使用有序逻辑回归估计比值比。结果:在接受调查的1519名成年人中,大多数是男性,年龄在40-59岁之间,初等教育程度不高。老年妇女和收入最高的五分之一人群的牙齿剩余率较低,假牙使用率较高,而去年接受过高等教育和牙科服务的人的牙齿剩余率较高。年龄在40-59岁之间、以治疗为目的使用牙科服务的男性对口腔健康的自我认知更差。结论:该研究强调需要有针对性的干预措施,以解决农村地区口腔健康的差距,强调预防措施和公平获得牙科服务的重要性。侧重于增加可及性和减少财政障碍的战略可有助于改善农村人口的口腔健康结果。
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引用次数: 0
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Community dentistry and oral epidemiology
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