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Bone involvement in chronic rhinosinusitis assessed by 99mTc-MDP bone SPECT. 99mTc-MDP骨SPECT评估慢性鼻窦炎的骨受累。
Pub Date : 2002-06-01 DOI: 10.1046/J.1365-2273.2002.00553.X
Y. Jang, T. Koo, S. Chung, Seok-Gun Park
To investigate the clinical significance of bone involvement in chronic rhinosinusitis, 99mTc-MDP bone single photon emission computed tomography (SPECT) was studied in 43 patients diagnosed as having chronic rhinosinusitis. Quantitative isotope uptake indices calculated on SPECT were compared between the patient and a control group, and between patients with a good postoperative outcome and those with a poor outcome. The patient group showed a significantly higher isotope uptake than the control group. The uptake of isotope in the ethmoid sinus areas in patients who had a poor postoperative outcome was significantly higher than those who had a good outcome. Our study suggests that patients with chronic rhinosinusitis have apparent bony involvement, and patients with more severe bone involvement may have a poorer treatment outcome.
为探讨慢性鼻窦炎骨受累的临床意义,对43例诊断为慢性鼻窦炎的患者进行99mTc-MDP骨单光子发射计算机断层扫描(SPECT)研究。在SPECT上计算的定量同位素摄取指数在患者和对照组之间,以及在术后预后良好的患者和预后较差的患者之间进行比较。患者组的同位素吸收量明显高于对照组。术后预后较差的患者的筛窦区同位素摄取明显高于预后良好的患者。我们的研究表明慢性鼻窦炎患者有明显的骨受累,骨受累越严重的患者治疗效果越差。
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引用次数: 32
Endoscopic marsupialization of congenital nasolacrimal duct cyst with dacryocoele. 先天性鼻泪管囊肿伴泪囊膨出的内镜有袋术。
Pub Date : 2002-06-01 DOI: 10.1046/J.1365-2273.2002.00556.X
D. Roy, N. Guevara, J. Santini, L. Castillo
A congenital nasolacrimal duct cyst is an uncommon condition in the newborn usually treated by ophthalmologists. Prolapse or expansion of the cyst into the nose may lead to respiratory distress and difficulty in feeding as newborns are obligate nose breathers, which needs the involvement of the Otolaryngologist in diagnosis and management. The authors report a series of 8 children presenting with a congenital nasolacrimal duct cyst and dacryocoele and highlight the importance of endoscopic nasal examination of newborns presenting with respiratory problems. Diagnostic studies included intranasal endoscopy and CT scanning of the nasolacrimal system and nose. All the patients were treated by endoscopic marsupialization of the cyst. Nasolacrimal duct abnormality should be considered in the differential diagnosis of neonatal respiratory distress and nasal obstruction. Nasal endoscopy is essential in the work-up of all children with nasal obstruction and respiratory distress. CT scanning is the investigative method of choice. Endoscopic marsupialization followed by lacrimal duct irrigation is effective in the treatment of congenital nasolacrimal duct cyst and results in complete resolution of symptoms.
先天性鼻泪管囊肿是一种罕见的新生儿疾病,通常由眼科医生治疗。囊肿脱垂或扩大到鼻子可能导致呼吸窘迫和进食困难,因为新生儿是专性的鼻子呼吸者,这需要耳鼻喉科医生参与诊断和处理。作者报告了8例先天性鼻泪管囊肿和泪孔的患儿,并强调了新生儿出现呼吸问题时鼻内镜检查的重要性。诊断研究包括鼻内窥镜检查和鼻泪系统和鼻子的CT扫描。所有患者均行内窥镜囊肿有袋化术。鼻泪管异常在新生儿呼吸窘迫和鼻塞的鉴别诊断中应予以考虑。鼻内窥镜检查是必不可少的工作,所有儿童的鼻塞和呼吸窘迫。CT扫描是首选的调查方法。内镜下有袋化术后泪管冲洗是治疗先天性鼻泪管囊肿的有效方法,可使症状完全缓解。
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引用次数: 32
The quality of life impact of dysphonia. 语音障碍对生活质量的影响。
Pub Date : 2002-06-01 DOI: 10.1046/J.1365-2273.2002.00559.X
J. Wilson, I. Deary, A. Millar, K. MacKenzie
Dysphonia can affect social life and employment, but formal studies of its general health impact are lacking. The aims of this study were (i) to compare self-rated general health status as measured by the SF-36 in a large cohort of dysphonic patients with those from normative groups; and (ii) to examine the differential impact of dysphonia on the various health status domains. The 163 dysphonic voice clinic attendees (38 men, 125 women) were drawn from recruits to a prospective trial of speech therapy efficacy. The Short-Form 36 (SF-36) scores were compared with published data on 744 age-matched healthy controls. Patients with dysphonia had significantly poorer self-reported health than the controls on all eight SF-36 subscales (limitation of physical activity P < 0.05; other seven, all P < 0.001, Student's t-test). We thus conclude that dysphonia in patients without obvious laryngeal disease has an adverse impact on all health status subscales as measured by the SF-36. The study provides further evidence for the inclusion quality of life measures in otolaryngology baseline and outcome assessments.
语音障碍可以影响社会生活和就业,但缺乏对其一般健康影响的正式研究。本研究的目的是:(i)比较一大群语音障碍患者的自评一般健康状况(由SF-36测量)与来自正常组的患者;(ii)检查语音障碍对各种健康状态域的不同影响。163名发声障碍临床参与者(38名男性,125名女性)是从新兵中挑选出来的,他们参加了一项言语治疗效果的前瞻性试验。研究人员比较了744名年龄匹配的健康对照者的SF-36得分。在所有8个SF-36亚量表上,语音障碍患者自我报告的健康状况明显差于对照组(体力活动限制P < 0.05;其他7个,均P < 0.001,学生t检验)。因此,我们得出结论,没有明显喉部疾病的患者的发音障碍对SF-36测量的所有健康状态亚量表都有不利影响。该研究为在耳鼻喉科基线和结果评估中纳入生活质量措施提供了进一步的证据。
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引用次数: 157
Rib graft reconstruction versus osseointegrated prosthesis for microtia: a significant change in patient preference. 肋骨移植重建与骨整合假体治疗小畸形:患者偏好的显著变化。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00454.X
M. Botma, A. Aymat, D. Gault, D. Albert
Until recently the options for reconstruction of the microtic ear were unsatisfactory and the ear was often left alone. With recent advances, both autologous rib reconstruction and osseointegration produce good quality results. It is our practice to offer all patients a choice of no surgery, autologous rib cartilage reconstruction or an osseointegrated prosthetic ear. This study reports on parental choice between the reconstructive options as assessed by questionnaire. Earlier patients who have had their surgery were compared with more recent patients who have chosen an option but are awaiting surgery. In the patients who have had surgery, seven (30%) chose a prosthetic ear and 16 (69.5%) chose rib cartilage reconstruction, compared to those patients that are awaiting surgery, four (11%) chose a prosthetic ear and 31 (88.6%) chose rib cartilage reconstruction. The results show a significant increase in the choice for rib cartilage reconstruction in those patients awaiting surgery. Although high quality autologous reconstruction is not widely available we feel it is important that parents are at least informed that it is an alternative to osseointegration and no surgery.
直到最近,重建微型耳的选择都不令人满意,耳朵经常被遗弃。近年来,自体肋骨重建和骨整合均取得了良好的效果。我们的做法是为所有患者提供不手术、自体肋软骨重建或骨整合假耳的选择。本研究以问卷的方式评估父母在重建方案之间的选择。较早接受手术的患者与最近选择手术但正在等待手术的患者进行比较。在已经手术的患者中,选择假耳的有7人(30%),选择肋软骨重建术的有16人(69.5%),而等待手术的患者中,选择假耳的有4人(11%),选择肋软骨重建术的有31人(88.6%)。结果显示,在等待手术的患者中,选择肋骨软骨重建的人数显著增加。虽然高质量的自体重建术尚未广泛应用,但我们认为重要的是至少让父母知道它是骨整合的一种替代方法,无需手术。
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引用次数: 21
Laryngoscopy findings in outpatient notes: the accuracy of the recording of the side of the lesion. 喉镜检查在门诊记录中的发现:病变侧面记录的准确性。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00460.X
P. Monnery, W. Smith, A. Hinton
An analysis of 100 patient notes was performed in the South-west Thames Region to determine the accuracy of recording the side of the abnormality in outpatient clinic notes when compared to the findings at direct laryngoscopy. Direct laryngoscopy was felt to be the most accurate method of viewing the larynx. The results were analysed to determine if the specific method of outpatient laryngoscopy or grade of examiner influenced the error rates. Inconsistencies occurred in 29% of the clinic notes when a diagram of the larynx was present. Specialist Registrars made 59% of the errors. Flexible nasendoscopy accounts for more errors than indirect laryngoscopy.
在西南泰晤士地区进行了100例患者笔记的分析,以确定记录的门诊记录异常侧的准确性与直接喉镜检查结果相比。直接喉镜检查被认为是观察喉部最准确的方法。对结果进行分析,以确定门诊喉镜检查的具体方法或检查人员的等级是否影响错误率。当喉图出现时,29%的临床记录不一致。专业注册商犯了59%的错误。柔性鼻内窥镜检查比间接喉镜检查更容易出错。
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引用次数: 1
A randomised trial of flexible versus rigid nasendoscopy in outpatient sinonasal examination. 弹性鼻内镜与刚性鼻内镜在门诊鼻窦检查中的随机对照试验。
Pub Date : 2001-08-01 DOI: 10.1046/J.0307-7772.2001.00463.X
K. Midwinter, A. Ahmed, D. Willatt
Nasendoscopy is used extensively in ENT clinics both as a diagnostic tool and for local postoperative care. Both flexible and rigid fibreoptic scopes are available for the purpose of sinonasal examination. A prospective study of a flexible versus rigid endoscope was carried out, randomly assigning one type of scope to each nostril of 56 patients presenting to clinic with sinonasal symptomatology. Patients awarded each type of scope a pain score on an analogue scale, according to the level of discomfort experienced, and the operator noted the number of structures seen. Significantly more structures were visualized with the rigid scope than the flexible scope (P = 0.05). The pain scores were similarly in favour of the rigid scope, showing a trend to less discomfort. The rigid nasendoscope is the scope of choice for sinonasal examinations in the outpatient clinic based on these data.
鼻内窥镜作为诊断工具和局部术后护理广泛应用于耳鼻喉科诊所。柔性和刚性纤维镜可用于鼻窦检查。对56例有鼻窦症状的患者进行了一项柔性内窥镜与刚性内窥镜的前瞻性研究,随机为每个鼻孔分配一种内窥镜。根据所经历的不适程度,患者在模拟量表上给每种范围的疼痛评分,操作员记录所见结构的数量。刚性镜显示的结构明显多于柔性镜(P = 0.05)。疼痛评分同样倾向于刚性范围,显示出较少不适的趋势。基于这些数据,刚性鼻内窥镜是门诊鼻窦检查的首选范围。
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引用次数: 16
The delivery of topical nasal sprays and drops to the middle meatus: a semiquantitative analysis. 局部鼻腔喷雾剂和滴剂到中鼻道的递送:半定量分析。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00473.X
A. Tsikoudas, J. Homer
The distribution of nasal drugs specifically to the middle meatus is of vital importance in the treatment of rhinosinusitis and nasal polyposis. It is widely assumed that the intranasal distribution is superior with nasal drops rather than spray delivery. However, a comparison of nasal spray and drop delivery specifically to this area has not been studied before. This study aims to compare semiquantitatively the intranasal distribution of nasal sprays and drops to the middle meatus in vivo. A novel method was used whereby a neurosurgical patty was placed in the middle meatus. Topical nasal drops and aqueous sprays dyed with methylene blue (0.1% v/v) were administered in a standardized fashion in normal volunteers. The subsequent absorption of administered dye was classified on a four-point scale. A randomized prospective cross-over design was used for the study. We found that there was no difference in the delivery of nasal drug to the middle meatus between either method of drug administration (P > 0.2). The perceived superiority of nasal drops may therefore be as a result of the acknowledged systemic effect of betamethasone drops.
鼻腔药物在鼻窦炎和鼻息肉病的治疗中具有重要意义。人们普遍认为鼻内滴剂比喷雾剂的分布更优越。然而,鼻腔喷雾剂和滴注剂对这一区域的特异性作用还没有进行过比较研究。本研究旨在半定量地比较鼻腔喷雾剂和滴剂在体内的鼻内分布。我们采用了一种新颖的方法,即将神经外科肉饼放置在正中肉道。用亚甲基蓝(0.1% v/v)染色的局部滴鼻液和水性喷雾剂在正常志愿者中以标准化的方式施用。随后对染料的吸收按四分制进行分类。本研究采用随机前瞻性交叉设计。我们发现两种给药方式在经鼻给药至中道的给药量上没有差异(P > 0.2)。因此,人们认为滴鼻液的优越性可能是由于倍他米松滴鼻液具有公认的全身作用。
{"title":"The delivery of topical nasal sprays and drops to the middle meatus: a semiquantitative analysis.","authors":"A. Tsikoudas, J. Homer","doi":"10.1046/J.1365-2273.2001.00473.X","DOIUrl":"https://doi.org/10.1046/J.1365-2273.2001.00473.X","url":null,"abstract":"The distribution of nasal drugs specifically to the middle meatus is of vital importance in the treatment of rhinosinusitis and nasal polyposis. It is widely assumed that the intranasal distribution is superior with nasal drops rather than spray delivery. However, a comparison of nasal spray and drop delivery specifically to this area has not been studied before. This study aims to compare semiquantitatively the intranasal distribution of nasal sprays and drops to the middle meatus in vivo. A novel method was used whereby a neurosurgical patty was placed in the middle meatus. Topical nasal drops and aqueous sprays dyed with methylene blue (0.1% v/v) were administered in a standardized fashion in normal volunteers. The subsequent absorption of administered dye was classified on a four-point scale. A randomized prospective cross-over design was used for the study. We found that there was no difference in the delivery of nasal drug to the middle meatus between either method of drug administration (P > 0.2). The perceived superiority of nasal drops may therefore be as a result of the acknowledged systemic effect of betamethasone drops.","PeriodicalId":10694,"journal":{"name":"Clinical otolaryngology and allied sciences","volume":"19 1","pages":"294-7"},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90430928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
The use of fibrin glue in refractory coagulopathic epistaxis. 纤维蛋白胶在难治性凝血致病性鼻出血中的应用。
Pub Date : 2001-08-01 DOI: 10.1046/J.0307-7772.2001.00469.X
P. Walshe, C. Harkin, S. Murphy, C. Shah, A. Curran, D. Mcshane
Epistaxis can be particularly difficult to treat when a patient has a coagulopathy, even if the area bleeding is visible. Where routine measures fail to arrest the bleeding (e.g., nasal cautery and packing), the application of fibrin glue is successful in stopping the bleeding without having to address the underlying coagulopathy. Ten patients with epistaxis secondary to an underlying coagulopathy were treated by local application of fibrin glue to the area bleeding. The bleeding stopped immediately in all patients when the fibrin glue was applied. No patients suffered complications. Fibrin glue application should be considered as a cost-effective means of controlling epistaxis from an identifiable area in the nasal cavity in patients with a coagulopathy.
当患者有凝血功能障碍时,即使出血区域可见,鼻出血也特别难以治疗。当常规措施不能止血时(例如,鼻烧灼和填塞),应用纤维蛋白胶可以成功止血,而不必解决潜在的凝血病。本文对10例继发于基础凝血功能障碍的鼻出血患者,采用纤维蛋白胶局部涂敷止血。所有患者在使用纤维蛋白胶后立即止血。没有患者出现并发症。纤维蛋白胶的应用应被认为是一种经济有效的方法来控制凝血功能障碍患者鼻腔内可识别区域的鼻出血。
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引用次数: 13
Study and application of a mathematical model for the provisional assessment of areas and nasal resistance, obtained using acoustic rhinometry and active anterior rhinomanometry. 使用声学鼻测量和主动前鼻测量获得的区域和鼻阻力临时评估的数学模型的研究和应用。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00470.X
G. Zambetti, M. Moresi, R. Romeo, F. Filiaci
Nasal resistance (NR) depends on the geometrical features and tortuosity of the nasal airway and on the air flow. Knowing the longitudinal distribution of cross-sectional areas (CSAs) in the nasal cavity (which can be obtained using acoustic rhinometry) and the laminar nasal resistance (obtainable by processing the rhinomanometric results), it is possible to calculate, utilizing a mathematical model elaborated on the basis of fluid dynamics, the differential nasal resistance (NRdiff) and the cumulative nasal resistance (NRcum), thus localizing the position at which the highest resistance is concentrated and the related longitudinal distribution. Using a mathematical model, we integrated the sigmoid curves DeltaP/Q of rhinomanometry with the cross-sectional areas obtained using acoustic rhinometry, thus obtaining the normal distribution of differential and cumulative nasal resistances. Afterwards, we empirically reduced the cross-sectional areas corresponding to the head, body, tail and the whole inferior turbinate, recalculating the differential and cumulative nasal resistance distribution curves. The results show that reduction of up to 50% of cross-sectional areas does not substantially affect the resistivity role of the nasal valve, while greater reductions move the highest resistivity point to an area at the junction of the body and the head of the inferior turbinate. The study of the differential nasal resistance trend curves as a function of the reduction of cross-sectional areas shows that the resistance variation of the body and the whole inferior turbinate prevail with reductions of up to 40%, while the variation of cross-sectional areas of the body bordering the inferior turbinate head is predominant with higher reductions. The cross-sectional areas of the nasal airway cavity with highest resistivity are mainly located in an anterior position, where the differential nasal resistances are higher, but there are substantial variations produced by reducing the cross-sectional area of the posterior nasal airway. A similar model can produce provisional values for the results obtainable with functional nasal surgery.
鼻阻力(NR)取决于鼻导气管的几何特征和弯曲度以及气流。知道鼻腔横截面积(csa)的纵向分布(可通过声学鼻测量获得)和层流鼻阻力(可通过处理鼻测量结果获得),就可以利用流体动力学基础上阐述的数学模型计算鼻部差阻(NRdiff)和累积鼻阻力(NRcum)。从而确定了最大阻力集中的位置和相关的纵向分布。通过建立数学模型,将鼻压测量的s形曲线DeltaP/Q与声学鼻压测量得到的横截面积进行积分,得到差异鼻阻力和累积鼻阻力的正态分布。然后,我们经验性地缩小了头、身、尾和整个下鼻甲对应的横截面积,重新计算了鼻阻力的差异分布曲线和累积分布曲线。结果表明,减少高达50%的截面积不会实质性影响鼻阀的电阻率作用,而更大的减少将最高电阻率点移动到身体和下鼻甲头部交界处的区域。对鼻阻力随截面积缩小的变化趋势曲线的研究表明,身体和整个下鼻甲的阻力变化占主导地位,减少幅度可达40%,而与下鼻甲头部接壤的身体截面积变化占主导地位,减少幅度较大。电阻率最高的鼻导气管腔截面积主要位于前位,此处鼻阻差较高,但减小后路鼻导气管截面积会产生较大的变化。类似的模型可以为功能性鼻手术的结果提供临时值。
{"title":"Study and application of a mathematical model for the provisional assessment of areas and nasal resistance, obtained using acoustic rhinometry and active anterior rhinomanometry.","authors":"G. Zambetti, M. Moresi, R. Romeo, F. Filiaci","doi":"10.1046/J.1365-2273.2001.00470.X","DOIUrl":"https://doi.org/10.1046/J.1365-2273.2001.00470.X","url":null,"abstract":"Nasal resistance (NR) depends on the geometrical features and tortuosity of the nasal airway and on the air flow. Knowing the longitudinal distribution of cross-sectional areas (CSAs) in the nasal cavity (which can be obtained using acoustic rhinometry) and the laminar nasal resistance (obtainable by processing the rhinomanometric results), it is possible to calculate, utilizing a mathematical model elaborated on the basis of fluid dynamics, the differential nasal resistance (NRdiff) and the cumulative nasal resistance (NRcum), thus localizing the position at which the highest resistance is concentrated and the related longitudinal distribution. Using a mathematical model, we integrated the sigmoid curves DeltaP/Q of rhinomanometry with the cross-sectional areas obtained using acoustic rhinometry, thus obtaining the normal distribution of differential and cumulative nasal resistances. Afterwards, we empirically reduced the cross-sectional areas corresponding to the head, body, tail and the whole inferior turbinate, recalculating the differential and cumulative nasal resistance distribution curves. The results show that reduction of up to 50% of cross-sectional areas does not substantially affect the resistivity role of the nasal valve, while greater reductions move the highest resistivity point to an area at the junction of the body and the head of the inferior turbinate. The study of the differential nasal resistance trend curves as a function of the reduction of cross-sectional areas shows that the resistance variation of the body and the whole inferior turbinate prevail with reductions of up to 40%, while the variation of cross-sectional areas of the body bordering the inferior turbinate head is predominant with higher reductions. The cross-sectional areas of the nasal airway cavity with highest resistivity are mainly located in an anterior position, where the differential nasal resistances are higher, but there are substantial variations produced by reducing the cross-sectional area of the posterior nasal airway. A similar model can produce provisional values for the results obtainable with functional nasal surgery.","PeriodicalId":10694,"journal":{"name":"Clinical otolaryngology and allied sciences","volume":"38 1","pages":"286-93"},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74645133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Mohs micrographic surgery for facial skin cancer. 面部皮肤癌的莫氏显微手术。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00484.X
H. Vuyk, P. Lohuis
Although it is well established that conventional treatment modalities generally result in high cure rates for non-melanoma skin cancer, it has been demonstrated over recent decades that the highest overall cure rates are achieved using Mohs micrographic surgery. The key to Mohs surgery is the excision and control of complete peripheral and deep resection margins in one plane, allowing orientation, mapping and re-excision of microscopic tumour extension. These extensions can be followed without sacrificing inappropriate amounts of normal tissue, yielding high cure rates and maximum preservation of tissue. These qualities make Mohs surgery an important and reliable treatment for skin cancer of the face, in particular when it concerns large, aggressive or recurrent carcinoma in cosmetic and functionally important areas. In an 8-year study period, 369 basal cell carcinomas (BCCs) and 56 squamous cell carcinomas (SCCs) of the face were treated in our department using Mohs surgery. With a follow-up ranging from 3 months to 99 months (mean 33 months), none of the BCCs recurred and only one (2%) of the SCCs recurred a few months postoperatively. These favourable cure rates using the modality of Mohs surgery are the reason for highlighting this technique in the current review.
虽然传统的治疗方式通常导致非黑色素瘤皮肤癌的高治愈率,但近几十年来已经证明,使用莫氏显微摄影手术获得了最高的总治愈率。Mohs手术的关键是在一个平面上切除和控制完整的外周和深部切除边缘,从而实现显微镜下肿瘤扩展的定位、定位和再切除。这些扩展可以在不牺牲适当数量的正常组织的情况下进行,从而获得高治愈率和最大限度地保存组织。这些特点使莫氏手术成为治疗面部皮肤癌的重要而可靠的方法,特别是当它涉及美容和功能重要区域的大的、侵袭性的或复发性的癌症时。在8年的研究期间,我科采用Mohs手术治疗了369例面部基底细胞癌(BCCs)和56例面部鳞状细胞癌(SCCs)。随访3 ~ 99个月(平均33个月),无一例bcc复发,仅有一例SCCs(2%)术后几个月复发。莫氏手术模式的良好治愈率是当前综述中强调该技术的原因。
{"title":"Mohs micrographic surgery for facial skin cancer.","authors":"H. Vuyk, P. Lohuis","doi":"10.1046/J.1365-2273.2001.00484.X","DOIUrl":"https://doi.org/10.1046/J.1365-2273.2001.00484.X","url":null,"abstract":"Although it is well established that conventional treatment modalities generally result in high cure rates for non-melanoma skin cancer, it has been demonstrated over recent decades that the highest overall cure rates are achieved using Mohs micrographic surgery. The key to Mohs surgery is the excision and control of complete peripheral and deep resection margins in one plane, allowing orientation, mapping and re-excision of microscopic tumour extension. These extensions can be followed without sacrificing inappropriate amounts of normal tissue, yielding high cure rates and maximum preservation of tissue. These qualities make Mohs surgery an important and reliable treatment for skin cancer of the face, in particular when it concerns large, aggressive or recurrent carcinoma in cosmetic and functionally important areas. In an 8-year study period, 369 basal cell carcinomas (BCCs) and 56 squamous cell carcinomas (SCCs) of the face were treated in our department using Mohs surgery. With a follow-up ranging from 3 months to 99 months (mean 33 months), none of the BCCs recurred and only one (2%) of the SCCs recurred a few months postoperatively. These favourable cure rates using the modality of Mohs surgery are the reason for highlighting this technique in the current review.","PeriodicalId":10694,"journal":{"name":"Clinical otolaryngology and allied sciences","volume":"20 1","pages":"265-73"},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82146408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 64
期刊
Clinical otolaryngology and allied sciences
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