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Clinical otolaryngology and allied sciences最新文献

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Watchful waiting in childhood otitis media with effusion. 儿童中耳炎伴积液的观察等待。
Pub Date : 2001-08-01 DOI: 10.1046/J.1365-2273.2001.00471.X
G. Browning
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引用次数: 14
Otolaryngology and the new undergraduate medical curriculum. 耳鼻喉科与新本科医学课程。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00448.X
R. Clarke, J. Fenton
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引用次数: 4
Review of management of drooling problems in neurologically impaired children: a review of methods and results over 6 years at Chailey Heritage Clinical Services. 对神经功能受损儿童流口水问题的管理综述:对Chailey Heritage临床服务6年来的方法和结果的回顾。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00434.X
R. V. Lloyd Faulconbridge, R. Tranter, V. Moffat, E. Green
Drooling can be a difficult problem for a child to endure, both physically and socially, especially if they are also having to cope with physical disabilities. Chailey Heritage Clinical Services and associated School look after a large number of severely physically disabled children and adolescents. This paper reviews the management strategy of the multidisciplinary oral-motor clinic at Chailey Heritage Clinical Services, and reviews the results of children treated between 1990 and 1996. The management ranges from oral-motor skills training through palatal training appliances to surgery. Seventy-eight children, ranging from 3 to 17 years, were treated and there were complete records for 73. Eighteen per cent responded to oral skills training alone. Thirty per cent of children had good results with a palatal training appliance and did not need any further intervention. Forty-seven per cent of patients underwent some form of surgery to control their drooling. Only 8% of children were treated with medication.
流口水对孩子来说是一个难以忍受的问题,无论是身体上还是社交上,特别是如果他们还必须应对身体残疾。Chailey传统临床服务和相关学校照顾大量严重身体残疾的儿童和青少年。本文回顾了Chailey Heritage临床服务多学科口腔运动诊所的管理策略,并回顾了1990年至1996年间儿童治疗的结果。治疗范围从口腔运动技能训练到腭训练器具再到手术。78名3至17岁的儿童接受了治疗,其中73人有完整的记录。18%的人只对口语技能训练有反应。30%的儿童使用上颚训练器效果良好,不需要任何进一步的干预。47%的患者接受了某种形式的手术来控制他们的流口水。只有8%的儿童接受了药物治疗。
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引用次数: 26
The aetiology of nasopharyngeal carcinoma. 鼻咽癌的病因学。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00449.X
A. McDermott, S. Dutt, J. Watkinson
Nasopharyngeal carcinoma is a disease with a remarkable racial and geographical distribution. In most parts of the world it is a rare condition and in only a handful of places does this low risk profile alter. These include the Southern Chinese, Eskimos and other Arctic natives, inhabitants of South-East Asia and also the populations of North Africa and Kuwait.
鼻咽癌是一种具有显著种族和地域分布的疾病。在世界上大多数地区,这是一种罕见的疾病,只有少数地方会改变这种低风险状况。这些人包括中国南方、爱斯基摩人和其他北极土著、东南亚居民以及北非和科威特的居民。
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引用次数: 127
First results of the VoiceMaster prosthesis in three centres in the Netherlands. VoiceMaster假肢在荷兰三个中心的初步结果。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00436.X
S. Eerenstein, P. Schouwenburg, L. van der Velden, M. D. De Boer
The VoiceMaster indwelling voice prosthesis was designed and developed for use in laryngectomized patients. The VoiceMaster pre-production model (0-series), tested during 1997 and 1998, proved to be a safe and valid concept. After the refining of a few technical details the currently available VoiceMaster device was introduced in June 1998. The preliminary results obtained with the device were encouraging and led to a multicentre study. The average device life span varies between the participating clinics, ranging up to 4.8 months. As there still are devices in situ, the average life span is still increasing. Factors such as stoma size and fistula position influence the insertion of the device and should be considered before VoiceMaster insertion. The general experience with the VoiceMaster prosthesis has proven it to be a worthwhile new device in prosthetic voice rehabilitation in laryngectomized patients.
VoiceMaster留置式语音假体是为喉切除患者设计和开发的。VoiceMaster预生产模型(0系列)在1997年和1998年进行了测试,证明是一个安全有效的概念。在完善了一些技术细节之后,1998年6月推出了目前可用的VoiceMaster设备。使用该设备获得的初步结果令人鼓舞,并导致了多中心的研究。参与的诊所的平均设备寿命各不相同,最长可达4.8个月。由于仍然有设备在原地,平均寿命仍在增加。诸如造口大小和瘘管位置等因素会影响设备的插入,在VoiceMaster插入之前应考虑这些因素。使用VoiceMaster假体的一般经验证明,它是一种有价值的新设备,用于喉切除术患者的假声康复。
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引用次数: 14
Anticipated absence from work ('sick leave') following routine ENT surgery: are we giving the correct advice? A postal questionnaire survey. 常规耳鼻喉科手术后预期的缺勤(“病假”):我们给出的建议是否正确?邮寄问卷调查。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00433.X
A. Chidambaram, A. Nigam, A. Cardozo
In the UK patients who undergo common ear, nose and throat (ENT) operations, and are employed, are advised to take 2 weeks sick leave before returning to their employment. A retrospective postal questionnaire survey (of adult patients who had undergone four common specific ENT operations) was conducted, to validate whether this preoperative advice given, was appropriate, and to attempt to assess the patient factors, which influenced the amount of postoperative absence from work. Among 218 questionnaires sent, 156 (71.6%) responses were returned and 132 (60.6%) were used. Analysis of the data for absence from work, showed that 58.3% had taken 2 weeks. The majority of patients (70.5%) stated that 2 weeks absence following their surgery was appropriate, whereas 5.3% reported that the period was excessive and 24.2% felt that it was inadequate. Postoperative pain (30.3%), infection (30.3%), bleeding (7.6%) and other causes (15.2%) were reported as the reasons for the delay to return to work. Nearly 31% of men and 55% of women had taken > 2 weeks of sick leave. In conclusion, the current practice of advising employed adults to take 2 weeks time off work following routine ENT surgery is appropriate. However, nearly 42% had taken > 2 weeks to return to their employment. Patients who underwent tonsillectomy and laser palatoplasty in general, required more time to recuperate prior to returning to work, when compared to those who had undergone septoplasty and functional endoscopic sinus surgery (FESS). Postoperative pain and infection were reported to be the main reasons for the delay in returning to work. Men, and self-employed patients returned to work earlier than women and other employed groups.
在英国,接受普通耳鼻喉(ENT)手术并受雇的患者,建议在重返工作岗位前请2周病假。我们进行了一项回顾性邮寄问卷调查(针对接受过四种常见的耳鼻喉科手术的成年患者),以验证术前给出的建议是否合适,并试图评估影响术后缺勤量的患者因素。共发放问卷218份,回收问卷156份(71.6%),使用问卷132份(60.6%)。对旷工数据的分析显示,58.3%的旷工时间为2周。大多数患者(70.5%)认为术后2周缺课是合适的,而5.3%的患者认为缺课时间过长,24.2%的患者认为缺课时间不足。术后疼痛(30.3%)、感染(30.3%)、出血(7.6%)和其他原因(15.2%)是延迟复工的原因。近31%的男性和55%的女性请过2周以上的病假。总之,目前建议成年就业者在常规耳鼻喉外科手术后休息2周是合适的。然而,近42%的人花了2周以上的时间才重返工作岗位。与接受鼻中隔成形术和功能性内窥镜鼻窦手术(FESS)的患者相比,接受扁桃体切除术和激光腭成形术的患者通常需要更多的时间来恢复工作。据报道,术后疼痛和感染是延迟返回工作岗位的主要原因。男性和个体户患者比女性和其他就业群体更早重返工作岗位。
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引用次数: 19
Pleomorphic adenomas of the major salivary glands: a study of the capsular form in relation to surgical management. 大唾液腺多形性腺瘤:囊状形态与手术处理的关系研究。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00440.X
A. Webb, J. Eveson
This was a retrospective study of 126 primary pleomorphic adenomas to correlate capsular characteristics with tumour histopathology in relation to current surgical debate (parotidectomy versus local excision). Capsular thickness was measured by micrometry and tumours classified into subtypes (1-4). Evidence of fine needle aspiration damage (needle tracks, infarction) was sought. Minimal changes were seen in eight tumours. Tumour growth features (bosselations, enveloping) were present in 57% and 33%, respectively, also microinvasion (42%) and tumour 'buds' (12%). Parotid lesions possessed thicker capsules than submandibular tumours. There was little correlation between capsular thickness and cellular structure. The significant exception was large (> 25 mm) hypocellular parotid tumours which had thinner capsules and could be vulnerable to operative rupture. In 110 standard operations (parotidectomy, submandibular gland excision), capsular exposure was evident in 81%. Field irrigation is recommended to lessen the risk of tumour seeding. This study reaffirms many elements of capsular weakness and suggests that parotidectomy is the operation of choice.
这是一项对126例原发性多形性腺瘤的回顾性研究,目的是将包膜特征与肿瘤组织病理学之间的关系与当前手术争论(腮腺切除术还是局部切除术)联系起来。用显微法测量包膜厚度,并将肿瘤分类为亚型(1-4)。寻找细针穿刺损伤(针迹、梗死)的证据。在8个肿瘤中观察到微小的变化。肿瘤生长特征(隆起、包膜)分别占57%和33%,还有微侵袭(42%)和肿瘤“芽”(12%)。腮腺病变具有比下颌骨肿瘤更厚的囊。荚膜厚度与细胞结构的关系不大。明显的例外是大的(bbb25mm)腮腺低细胞肿瘤,其囊膜较薄,容易手术破裂。在110例标准手术(腮腺切除术、颌下腺切除术)中,有81%的患者有明显的囊膜暴露。建议田间灌溉以减少肿瘤播种的风险。本研究重申了包膜无力的许多因素,并建议腮腺切除术是首选手术。
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引用次数: 64
The management of the neck in squamous head and neck cancer. 鳞状头颈癌颈部的处理。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00443.X
A. Robson
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引用次数: 7
Hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): otorhinolaryngological manifestations. 遗传性出血性毛细血管扩张(Osler-Weber-Rendu综合征):耳鼻喉科表现。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00442.X
H. Pau, Andrew Carney, G. Murty
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder affecting blood vessels of the skin, mucous membrane and viscera. The otorhinolaryngologist is the commonest clinician involved in management as epistaxis occurs in 93% of the patients. As marked advances have recently been made regarding the pathogenesis and management of the condition, the otorhinolaryngological perspective is reviewed.
遗传性出血性毛细血管扩张症(HHT)是一种常染色体显性遗传病,影响皮肤、粘膜和内脏血管。鼻出血发生在93%的患者中,耳鼻喉科医生是最常见的临床医生。由于最近在该病的发病机制和治疗方面取得了显著的进展,本文从耳鼻喉科的角度进行了综述。
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引用次数: 52
The clinicopathological significance of bcl-2 expression in the surgical treatment of laryngeal carcinoma. bcl-2表达在喉癌手术治疗中的临床病理意义。
Pub Date : 2001-04-01 DOI: 10.1046/J.1365-2273.2001.00441.X
A. Yuen, K. Lam, J. Choy, W. Ho, W. Wei
Bcl-2 expression was studied by immunohistochemistry on laryngectomy specimens from 176 patients. Of the 176 tumours, 11% had positive bcl-2 staining. Bcl-2 expression was significantly correlated with tumour grade: 5% of well-differentiated tumours, 12% of moderately-differentiated tumours and 23% of poorly-differentiated tumours had positive expression of bcl-2. Nodal metastases were also found to be significantly related to bcl-2 expression: 36% of nodal metastases for negative bcl-2 expression compared with 70% for positive expression. The risk of nodal metastases increased significantly with the presence of bcl-2 expression, moderate or poor differentiation and supraglottic involvement. The risk of nodal metastases increased significantly with the presence of increasing numbers of risk factors: 11% without risk factor, 21% with one risk factor, 49% with two risk factors and 77% with three risk factors. Bcl-2 expression in laryngeal carcinoma is significantly correlated with tumour grade and nodal metastases. It has added prognostic value for nodal metastases together with tumour grade and site of tumour involvement.
应用免疫组化方法研究了176例喉切除术标本中Bcl-2的表达。在176个肿瘤中,11%的肿瘤bcl-2染色阳性。Bcl-2表达与肿瘤分级显著相关:5%的高分化肿瘤、12%的中分化肿瘤和23%的低分化肿瘤有Bcl-2阳性表达。淋巴结转移也与bcl-2表达显著相关:bcl-2阴性表达的淋巴结转移率为36%,而bcl-2阳性表达的则为70%。随着bcl-2表达、分化程度中等或较差以及声门上受损伤,淋巴结转移的风险显著增加。随着危险因素数量的增加,淋巴结转移的风险显著增加:无危险因素占11%,有一个危险因素占21%,有两个危险因素占49%,有三个危险因素占77%。Bcl-2在喉癌中的表达与肿瘤分级及淋巴结转移有显著相关性。它增加了淋巴结转移的预后价值,以及肿瘤的分级和肿瘤累及的部位。
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引用次数: 18
期刊
Clinical otolaryngology and allied sciences
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