Grigoriy E. Roytberg, N. V. Kondratova, O. V. Strunin, Igor’ V. Smirnov
Providing medical care based on a patient-centered medicine model supposes close collaboration with patients and their families based on partnership. The development of action plan aimed on implementation of comfortable conditions for the child during surgery and anesthesia, considering his needs and age characteristics, is a topical issue in pediatrics. This article provides an organizational model for anesthesia in child-friendly environment and covers all the main stages of the patient's stay in the hospital.
{"title":"Organization and Implementation of Patient-Centered Anesthesia in Children in Terms of the Surgical Department in the Multidisciplinary Hospital","authors":"Grigoriy E. Roytberg, N. V. Kondratova, O. V. Strunin, Igor’ V. Smirnov","doi":"10.15690/vsp.v22i6.2659","DOIUrl":"https://doi.org/10.15690/vsp.v22i6.2659","url":null,"abstract":"Providing medical care based on a patient-centered medicine model supposes close collaboration with patients and their families based on partnership. The development of action plan aimed on implementation of comfortable conditions for the child during surgery and anesthesia, considering his needs and age characteristics, is a topical issue in pediatrics. This article provides an organizational model for anesthesia in child-friendly environment and covers all the main stages of the patient's stay in the hospital.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":" 129","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139628179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The article presents the results of historical and medical research reflecting the issues of reforming children’s health care after the World War II. The aim of the study is to present the problems of reforming children’s health care in the USSR in the post-war decade (1946–1956). The study relevance is defined by necessity to examine the historical experience of reforming children’s health care during the most difficult for our country post-war period so we can learn crucial lessons from the past and use them further for the successful implementation of the federal project “Development of children’s health care, including the creation of modern infrastructure for medical care provision for children”. Published and unpublished documents of the USSR Ministry of Health and the USSR Academy of Medical Sciences, stored in the State Archive of the Russian Federation, as well as publications from medical journals, scientific collections, monographs were studied to cover this issue. The analysis of this study has shown that the most significant part in the state health reform started in the first post-war years was the merger of hospitals and clinics for adults, maternity hospitals with women’s consultations, children’s hospitals with children’s consultations and outpatients’ clinics. The post-war reform has contributed to the improvement of the quality of inpatient and outpatient medical care, to the increasing role of the hospital as the organizing and leading center of all united facilities. The integration of children’s hospitals with consultations and outpatients’ clinic, as well as the organization of the primary pediatric care according to the system of medical and preventive care provision for children aged from birth to 16 years by single pediatrician, have shown succession in the work of primary care doctors and hospitals. The increase in the health workers qualifications, the development of specialized types of medical care, the improvement in the quality of medical and preventive care were observed. The reform of children’s health care contributed to the diseases’ timely diagnosis and early patients’ hospitalization, strengthening the connection of the primary care doctor and nurse with the child’s family, and decreasing of child morbidity and mortality.
{"title":"Reforming Children’s Health Care in the Soviet Union after the World War II","authors":"Valerii Y. Albitskiy, S. A. Sher","doi":"10.15690/vsp.v22i6.2655","DOIUrl":"https://doi.org/10.15690/vsp.v22i6.2655","url":null,"abstract":"The article presents the results of historical and medical research reflecting the issues of reforming children’s health care after the World War II. The aim of the study is to present the problems of reforming children’s health care in the USSR in the post-war decade (1946–1956). The study relevance is defined by necessity to examine the historical experience of reforming children’s health care during the most difficult for our country post-war period so we can learn crucial lessons from the past and use them further for the successful implementation of the federal project “Development of children’s health care, including the creation of modern infrastructure for medical care provision for children”. Published and unpublished documents of the USSR Ministry of Health and the USSR Academy of Medical Sciences, stored in the State Archive of the Russian Federation, as well as publications from medical journals, scientific collections, monographs were studied to cover this issue. The analysis of this study has shown that the most significant part in the state health reform started in the first post-war years was the merger of hospitals and clinics for adults, maternity hospitals with women’s consultations, children’s hospitals with children’s consultations and outpatients’ clinics. The post-war reform has contributed to the improvement of the quality of inpatient and outpatient medical care, to the increasing role of the hospital as the organizing and leading center of all united facilities. The integration of children’s hospitals with consultations and outpatients’ clinic, as well as the organization of the primary pediatric care according to the system of medical and preventive care provision for children aged from birth to 16 years by single pediatrician, have shown succession in the work of primary care doctors and hospitals. The increase in the health workers qualifications, the development of specialized types of medical care, the improvement in the quality of medical and preventive care were observed. The reform of children’s health care contributed to the diseases’ timely diagnosis and early patients’ hospitalization, strengthening the connection of the primary care doctor and nurse with the child’s family, and decreasing of child morbidity and mortality.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139627734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
20 ноября ежегодно в России и других странах отмечается Международный день педиатра.
每年 11 月 20 日，俄罗斯和其他国家都会庆祝国际儿科医生日。
{"title":"International pediatrician’s day","authors":"Stella A. Sher","doi":"10.15690/vsp.v22i6.2650","DOIUrl":"https://doi.org/10.15690/vsp.v22i6.2650","url":null,"abstract":"20 ноября ежегодно в России и других странах отмечается Международный день педиатра. ","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":" 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139628175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This review provides data on the use of yogurts in infants’ nutrition. The properties of these fermented milk products and associated urgent and delayed sanogenetic effects are described. The experience of yogurts (enriched with pre- and probiotics) implementation in the nutrition therapy of children who have undergone infectious diseases is shown. The yogurt usage for intestinal microbiota disorders correction in children with functional digestive disorders and chronic somatic pathology is discussed.
{"title":"Yoghurts in Infants’ Nutrition: Opportunities of Infectious and Non-Communicable Diseases’ Prevention","authors":"I. Belyaeva, E. Bombardirova, T. Turti","doi":"10.15690/vsp.v22i4.2591","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2591","url":null,"abstract":"This review provides data on the use of yogurts in infants’ nutrition. The properties of these fermented milk products and associated urgent and delayed sanogenetic effects are described. The experience of yogurts (enriched with pre- and probiotics) implementation in the nutrition therapy of children who have undergone infectious diseases is shown. The yogurt usage for intestinal microbiota disorders correction in children with functional digestive disorders and chronic somatic pathology is discussed.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87545103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Adamyan, E. Sibirskaya, I. Karachentsova, L. Pivazyan, M.A. Loshkareva, Y. Kirillova, Sabina K. Murvatova, K. Murvatova
Background. Abnormal uterine bleeding (AUB) in adolescence is one of the urgent problems of medicine nowadays. It is on the 2nd place among all the reasons for hospitalization in gynecological departments, and its incidence among girls during puberty is 50%. Clinical case description. This is the clinical case of 15-year-old girl admitted to the gynecology department with complaints on long-lasting bloody vaginal discharge, fatigue, dizziness. The diagnosis of «abnormal uterine bleeding in adolescence» burdened with iron deficiency anemia (IDA) was established according to laboratory and instrumental examinations. The patient underwent RBC-transfusion with specific buffy coat and was administered with hormonal hemostatic and anti-anemic therapy. Conclusion. We can conclude (with reference to this observation and the reviewed literature) not only that IDA is one of the most common complications of AUB in adolescence, but also what management should be used in such clinical cases.
{"title":"Abnormal Uterine Bleeding in Adolescence Burdened with Severe Anemia: Clinical Case","authors":"L. Adamyan, E. Sibirskaya, I. Karachentsova, L. Pivazyan, M.A. Loshkareva, Y. Kirillova, Sabina K. Murvatova, K. Murvatova","doi":"10.15690/vsp.v22i4.2612","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2612","url":null,"abstract":"Background. Abnormal uterine bleeding (AUB) in adolescence is one of the urgent problems of medicine nowadays. It is on the 2nd place among all the reasons for hospitalization in gynecological departments, and its incidence among girls during puberty is 50%. Clinical case description. This is the clinical case of 15-year-old girl admitted to the gynecology department with complaints on long-lasting bloody vaginal discharge, fatigue, dizziness. The diagnosis of «abnormal uterine bleeding in adolescence» burdened with iron deficiency anemia (IDA) was established according to laboratory and instrumental examinations. The patient underwent RBC-transfusion with specific buffy coat and was administered with hormonal hemostatic and anti-anemic therapy. Conclusion. We can conclude (with reference to this observation and the reviewed literature) not only that IDA is one of the most common complications of AUB in adolescence, but also what management should be used in such clinical cases.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75423118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
1 сентября (12 сентября по новому стилю) 1763 года навсегда вошло как красная дата в историю развития российской системы охраны здоровья матери и ребенка, отечественной педиатрической науки и практики. В этот день 260 лет назад императрица Екатерина Вторая подписала Манифест об учреждении в Москве «Сиропитального дома» с госпиталем для бедных родильниц, названного Императорским Московским воспитательным домом (ИМВД).
{"title":"Remarkable Event in the History of Russian Children Healthcare (to the 260th Anniversary of the Imperial Moscow Orphanage Foundation)","authors":"Alexander A. Baranov, V. Albitskiy","doi":"10.15690/vsp.v22i4.2590","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2590","url":null,"abstract":"1 сентября (12 сентября по новому стилю) 1763 года навсегда вошло как красная дата в историю развития российской системы охраны здоровья матери и ребенка, отечественной педиатрической науки и практики. В этот день 260 лет назад императрица Екатерина Вторая подписала Манифест об учреждении в Москве «Сиропитального дома» с госпиталем для бедных родильниц, названного Императорским Московским воспитательным домом (ИМВД).","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78648710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Drug dosing remains one of the topical issues of modern pediatrics. Insufficient number of clinical studies, vulnerable patient populations (preterm newborns, patients with renal and/or hepatic insufficiency, obesity), and high risk of polypragmasy create additional difficulties for practicing physicians. This review provides description of currently used approaches to drugs dosing in children. It has been shown that prognostic models should be used for solving drugs dosing issues regarding characteristics of young patients. Such models include: physiologically based pharmacokinetic modelling; population pharmacokinetic analysis; model-based precision dosing; modeling and simulation approach; use of real world data; and pharmacogenetic testing-based dosing. These models use information from preclinical and clinical stu
{"title":"Drug Dosing in Pediatrics: Possible Approaches","authors":"A. Kolbin, K. S. Radaeva","doi":"10.15690/vsp.v22i4.2593","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2593","url":null,"abstract":"Drug dosing remains one of the topical issues of modern pediatrics. Insufficient number of clinical studies, vulnerable patient populations (preterm newborns, patients with renal and/or hepatic insufficiency, obesity), and high risk of polypragmasy create additional difficulties for practicing physicians. This review provides description of currently used approaches to drugs dosing in children. It has been shown that prognostic models should be used for solving drugs dosing issues regarding characteristics of young patients. Such models include: physiologically based pharmacokinetic modelling; population pharmacokinetic analysis; model-based precision dosing; modeling and simulation approach; use of real world data; and pharmacogenetic testing-based dosing. These models use information from preclinical and clinical stu","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85492161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Kupriyanova, G. Karkashadze, N. Zhurkova, Leila S. Namova-Baranova, A. Mamedyarov
Congenital aniridia manifests with total or partial absence of the iris. The association of the disease with the PAX6 gene has been proven. Changes in the PAX6 structure lead to intrauterine pathology, visual organ malformation, malformation of master regulator proteins of organogenesis affecting various cells’ differentiation (central nervous system cells included). Such disorders result into the development of PAX6-associated syndromes with various brain malformations, neurological disorders, and systemic pathology (thyroid pathology, Wilms tumor, glucose intolerance). Isolated congenital aniridia is also accompanied by psychoneurological disorders. It can be associated with brain structures’ disorders during embryogenesis and with impact of external stress factors on the child (frequent medical checkup, surgical treatments). The psychoneurological disorders’ pathogenesis as well as congenital aniridia’s genetic mechanisms remain unclear. Thus, it is crucial to review new relevant data within the context of previously obtained information to gather full picture of the clinical signs of the disease and to improve the management of children with congenital aniridia.
{"title":"Psychoneurological Disorders in Children with Congenital Aniridia and PAX6-Associated Syndromes","authors":"O. Kupriyanova, G. Karkashadze, N. Zhurkova, Leila S. Namova-Baranova, A. Mamedyarov","doi":"10.15690/vsp.v22i4.2611","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2611","url":null,"abstract":"Congenital aniridia manifests with total or partial absence of the iris. The association of the disease with the PAX6 gene has been proven. Changes in the PAX6 structure lead to intrauterine pathology, visual organ malformation, malformation of master regulator proteins of organogenesis affecting various cells’ differentiation (central nervous system cells included). Such disorders result into the development of PAX6-associated syndromes with various brain malformations, neurological disorders, and systemic pathology (thyroid pathology, Wilms tumor, glucose intolerance). Isolated congenital aniridia is also accompanied by psychoneurological disorders. It can be associated with brain structures’ disorders during embryogenesis and with impact of external stress factors on the child (frequent medical checkup, surgical treatments). The psychoneurological disorders’ pathogenesis as well as congenital aniridia’s genetic mechanisms remain unclear. Thus, it is crucial to review new relevant data within the context of previously obtained information to gather full picture of the clinical signs of the disease and to improve the management of children with congenital aniridia.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85940335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
В период с 3 по 5 марта 2023 г. в Москве проводилась II Всероссийская вакцинальная Ассамблея «Защищая поколения», в рамках которой состоялось 14 научных симпозиумов, пленарных заседаний, круглых столов и экспертных советов, посвященных наиболее актуальным вопросам отечественной и глобальной иммунопрофилактики инфекционных болезней.
{"title":"Resolution of the II All-Russian Vaccine Assembly “Protecting Generations”","authors":"A. Editorial","doi":"10.15690/vsp.v22i4.2597","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2597","url":null,"abstract":"В период с 3 по 5 марта 2023 г. в Москве проводилась II Всероссийская вакцинальная Ассамблея «Защищая поколения», в рамках которой состоялось 14 научных симпозиумов, пленарных заседаний, круглых столов и экспертных советов, посвященных наиболее актуальным вопросам отечественной и глобальной иммунопрофилактики инфекционных болезней.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"260 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74706625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Vashakmadze, N. Zhurkova, E. Zakharova, Ludmila K. Mikhaylova, Marina A. Babaykina
Background. Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked recessive disease caused by lysosomal enzyme iduronate-2-sulfatase deficiency resulting in progressive glycosaminoglycans (GAG) accumulation in tissues (dermatan sulfate and heparan sulfate). GAG accumulation in cells leads to the development of progressive pathological disorders, malfunction of various organs and systems, early disability, and decrease in life expectancy. Enzyme replacement therapy (ERT) reduces the rate of life-threatening conditions development in patient. ERT would be more effective if it is prescribed early, especially at preclinical stage. This is the time when there are no severe irreversible changes in the cell, thus, pathogenetic therapy will decrease GAG accumulation in lysosomes, slow down the pathological process, and improve patient's condition. Clinical case description. Male patient diagnosed with MPS II was administrated with ERT idursulfase beta at the age of 6 months. It led to milder disease course compared to proband uncle who had similar mutation in the IDS gene, severe disease phenotype, and later initiation of ERT (at the age of 2.5 years). Conclusion. Early ERT initiation in patients with MPS II significantly slows down development of severe and life-threatening complications, increases the duration and improves the quality of life.
背景。粘多糖病II型(MPS II, Hunter综合征)是一种x连锁隐性疾病，由溶酶体伊杜醛酸-2-硫酸酯酶缺乏引起，导致组织(硫酸皮聚糖和硫酸肝素)中糖胺聚糖(GAG)的进行性积累。GAG在细胞中的积累导致进行性病理疾病的发展，各种器官和系统功能障碍，早期残疾和预期寿命降低。酶替代疗法(ERT)降低了患者危及生命的疾病发展的速度。如果在早期，特别是在临床前阶段开ERT会更有效。此时细胞内还没有发生严重的不可逆变化，因此病理学治疗可以减少GAG在溶酶体中的积累，减缓病理过程，改善患者的病情。临床病例描述。诊断为MPS II的男性患者在6个月大时给予ERT idursulase β。与IDS基因相似突变的先证者叔叔相比，其病程较轻，疾病表型严重，ERT开始较晚(2.5岁)。结论。MPS II患者早期启动ERT可显著减缓严重和危及生命的并发症的发展，增加持续时间并改善生活质量。
{"title":"Idursulfase Beta (Hunterase) Therapeutic Experience in a Patient with Mucopolysaccharidosis Type II","authors":"N. Vashakmadze, N. Zhurkova, E. Zakharova, Ludmila K. Mikhaylova, Marina A. Babaykina","doi":"10.15690/vsp.v22i4.2613","DOIUrl":"https://doi.org/10.15690/vsp.v22i4.2613","url":null,"abstract":"Background. Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked recessive disease caused by lysosomal enzyme iduronate-2-sulfatase deficiency resulting in progressive glycosaminoglycans (GAG) accumulation in tissues (dermatan sulfate and heparan sulfate). GAG accumulation in cells leads to the development of progressive pathological disorders, malfunction of various organs and systems, early disability, and decrease in life expectancy. Enzyme replacement therapy (ERT) reduces the rate of life-threatening conditions development in patient. ERT would be more effective if it is prescribed early, especially at preclinical stage. This is the time when there are no severe irreversible changes in the cell, thus, pathogenetic therapy will decrease GAG accumulation in lysosomes, slow down the pathological process, and improve patient's condition. Clinical case description. Male patient diagnosed with MPS II was administrated with ERT idursulfase beta at the age of 6 months. It led to milder disease course compared to proband uncle who had similar mutation in the IDS gene, severe disease phenotype, and later initiation of ERT (at the age of 2.5 years). Conclusion. Early ERT initiation in patients with MPS II significantly slows down development of severe and life-threatening complications, increases the duration and improves the quality of life.","PeriodicalId":10867,"journal":{"name":"Current pediatrics","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84371325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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