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Current Treatment Options in Rheumatology最新文献

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Painful Knee Osteoarthritis and Radiofrequency Neurotomy of Genicular Nerves 疼痛性膝骨关节炎和膝神经射频神经切开术
Pub Date : 2023-05-15 DOI: 10.1007/s40674-023-00204-0
E. Ertilav, S. Sari, O. N. Aydın
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引用次数: 0
The Contribution of the Psychologist in the Assessment and Treatment of Fibromyalgia 心理学家在纤维肌痛的评估和治疗中的贡献
Pub Date : 2023-04-13 DOI: 10.1007/s40674-023-00200-4
Juan V. Luciano, R. Neblett, C. Peñacoba, C. Suso‐Ribera, L. McCracken
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引用次数: 0
Intra-articular Mineralization and Association with Osteoarthritis Development and Outcomes 关节内矿化与骨关节炎发展和预后的关系
Pub Date : 2023-04-05 DOI: 10.1007/s40674-023-00203-1
Jean W. Liew
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引用次数: 0
Pathogenesis and Treatment in IMNM IMNM的发病机制及治疗
Pub Date : 2023-03-22 DOI: 10.1007/s40674-023-00201-3
Charles-Antoine Dallevet, O. Benveniste, Y. Allenbach
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引用次数: 0
Virtual Tools to Enable Management of Knee Osteoarthritis. 实现膝骨关节炎管理的虚拟工具。
Pub Date : 2023-03-11 DOI: 10.1007/s40674-023-00202-2
Rana S Hinman, Belinda J Lawford, Rachel K Nelligan, Kim L Bennell

Purpose of review: There is increasing recognition that virtual tools, enabled by the internet and telecommunications technology, can increase access to health care. We review evidence about the clinical effectiveness and acceptability of telephone-delivered and videoconferencing clinician consultations, websites and internet-delivered programs, and SMS and mobile applications in enabling the management of people with knee osteoarthritis (OA). We discuss barriers to using virtual tools and suggest strategies to facilitate implementation in clinical settings.

Recent findings: An increasing number of systematic reviews, meta-analyses, and clinical trials provide evidence showing the effectiveness of virtual tools for improving knee OA management. Qualitative research shows that virtual tools increase patient access to knee OA care, are generally acceptable and convenient for patients, but can be associated with barriers to use from patient and clinician perspectives.

Summary: Virtual tools offer new opportunities to enable people with knee OA to manage their condition and receive care that may otherwise be difficult or not possible to access. Telephone calls and videoconferencing can be used for real-time synchronous consultations between clinicians and patients, increasing the geographic reach of health services. Websites and internet-based programs can be used to educate patients about their condition, as well as deliver exercise, weight management, and psychological interventions. Mobile apps can monitor and track OA symptoms, exercise, and physical activity, while SMS can facilitate positive behaviour changes for self-management over the long-term when sustained clinician contact may not be possible.

审查目的:人们越来越认识到,通过互联网和电信技术实现的虚拟工具可以增加获得医疗保健的机会。我们审查了有关电话和视频会议临床医生咨询、网站和互联网提供的程序以及短信和移动应用程序在膝骨关节炎(OA)患者管理方面的临床有效性和可接受性的证据。我们讨论了使用虚拟工具的障碍,并提出了在临床环境中促进实施的策略。最近的发现:越来越多的系统综述、荟萃分析和临床试验提供了证据,表明虚拟工具在改善膝关节骨性关节炎管理方面的有效性。定性研究表明,虚拟工具增加了患者获得膝关节骨性关节炎护理的机会,通常对患者来说是可接受和方便的,但从患者和临床医生的角度来看,可能与使用障碍有关。摘要:虚拟工具提供了新的机会,使膝关节骨性关节炎患者能够管理自己的病情,并接受可能难以或不可能获得的护理。电话和视频会议可以用于临床医生和患者之间的实时同步咨询,增加卫生服务的地理覆盖范围。网站和基于互联网的项目可以用来教育患者了解他们的病情,以及提供锻炼、体重管理和心理干预。移动应用程序可以监测和跟踪OA症状、锻炼和身体活动,而当临床医生可能无法持续接触时,短信可以促进积极的行为改变,以便长期自我管理。
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引用次数: 0
An Unusual Presentation of ANCA-Negative Granulomatosis With Polyangiitis (GPA) in the Gynecological Tract and Literature Review anca阴性肉芽肿病伴多血管炎(GPA)在妇科的不寻常表现及文献复习
Pub Date : 2023-01-12 DOI: 10.1007/s40674-022-00199-0
Arpita Gantayet, P. Plantinga, J. Pope
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引用次数: 0
Utility of Myositis-Specific Autoantibodies for Treatment Selection in Myositis. 肌炎特异性自身抗体在肌炎治疗选择中的应用。
Pub Date : 2022-12-01 Epub Date: 2022-09-28 DOI: 10.1007/s40674-022-00198-1
Maria Casal-Dominguez, Iago Pinal-Fernández, Andrew L Mammen

Purpose of review: Autoimmune myopathies (IMs) are a group of diseases characterized by muscle weakness and inflammatory infiltrates on the muscle biopsy. 'However, muscle involvement is not always present and other organs and tissues (lung, skin, and joints) are commonly affected. The most accepted classification for IM includes dermatomyositis, sporadic inclusion body myositis, immune-mediated necrotizing myopathy, polymyositis, and overlap myositis. Seventy percent of the autoantibodies that IM patients have are myositis-specific autoantibodies (MSAs). Importantly, MSAs are associated with specific clinical phenotypes in IM patients. The therapy of IMs consists of glucocorticoids, immunosuppressants, biologic, and immunomodulatory drugs, but there is recent evidence that patients with some types of MSAs respond better to certain treatments. The purpose of this review is to summarize the IM treatment from an autoantibody perspective.

Recent findings: Each MSA is maybe associated with the activation of specific pathogenic pathways which can be effectively targeted by specific drugs. The last few years have shown multiple examples of successful treatments for each MSA group of patients as we will describe in the following paragraphs.

Summary: The adverse effects of the IM therapeutic agents and some patients' refractoriness call for a continued search for better and more targeted therapies. MSA groups should be considered for a treatment decision.

综述目的:自身免疫性肌病(IMs)是一组以肌肉无力和肌肉活检炎症浸润为特征的疾病。“然而,并不总是肌肉受累,其他器官和组织(肺、皮肤和关节)通常会受到影响。”最被接受的IM分类包括皮肌炎、散发性包涵体肌炎、免疫介导的坏死性肌病、多发性肌炎和重叠性肌炎。IM患者70%的自身抗体是肌炎特异性自身抗体(msa)。重要的是,msa与IM患者的特定临床表型相关。IMs的治疗包括糖皮质激素、免疫抑制剂、生物和免疫调节药物,但最近有证据表明,某些类型的msa患者对某些治疗的反应更好。本文的目的是从自身抗体的角度总结IM的治疗。最新发现:每种MSA可能与特定致病途径的激活有关,可被特定药物有效靶向。在过去的几年里,我们将在下面的段落中描述每个MSA组患者成功治疗的多个例子。摘要:IM治疗药物的不良反应和一些患者的难治性要求我们继续寻找更好和更有针对性的治疗方法。在作出治疗决定时应考虑MSA组。
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引用次数: 0
Biomarkers in Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD) 系统性硬化症相关间质性肺疾病(SSc-ILD)的生物标志物
Pub Date : 2022-09-24 DOI: 10.1007/s40674-022-00196-3
Alice Cole, C. Denton
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引用次数: 2
Tailored Interventions for Supporting Physical Activity Participation in People with Arthritis and Related Conditions: a Systematic Review 支持关节炎及相关疾病患者参与体育活动的量身定制干预措施:一项系统综述
Pub Date : 2022-08-20 DOI: 10.1007/s40674-022-00194-5
Jasmin K. Ma, Smruthi Ramachandran, Amrit Sandhu, Karen Tsui, A. Hoens, Davin Hu, Linda C. Li
{"title":"Tailored Interventions for Supporting Physical Activity Participation in People with Arthritis and Related Conditions: a Systematic Review","authors":"Jasmin K. Ma, Smruthi Ramachandran, Amrit Sandhu, Karen Tsui, A. Hoens, Davin Hu, Linda C. Li","doi":"10.1007/s40674-022-00194-5","DOIUrl":"https://doi.org/10.1007/s40674-022-00194-5","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"191 1","pages":"117 - 142"},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77493626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bisphosphonate Drug Holiday and Fracture Risk: Reviewing the Evidence 双膦酸盐药物假期与骨折风险:回顾证据
Pub Date : 2022-07-06 DOI: 10.1007/s40674-022-00191-8
A. Adams, Denison S. Ryan, A. Lawless, Heidi Fischer
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引用次数: 0
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Current Treatment Options in Rheumatology
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