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The use of pilocarpine in the treatment of presbyopia 匹罗卡品在老花眼治疗中的应用
Pub Date : 2022-09-30 DOI: 10.24292/01.ot.300922.3
D. Szumny
Presbyopia is a physiological process of progressive loss of accommodation, which leads to a deterioration in the ability to focus vision on objects at different distances. This is now thought to be a direct consequence of two causes: the design of the transparent lens and the way it has to change shape to allow focusing, and the instability of proteins over very long periods of time. In recent years, various substances that temporarily narrow the pupil, causing a pinhole effect, have been intensively investigated to allow improved near vision acuity. The most commonly researched is 1.25% pilocarpine solution. The substance itself has been known for more than 100 years, with a well-documented hypotensive effect and numerous side effects. However, the reduced concentration and less frequent dosing, as well as the addition of drugs with anti-inflammatory effects currently being studied, offer hope for efficacy in the treatment of presbyopia. The results of the studies so far are promising. Researchers point to improved near visual acuity and a low rate of mild side effects. In the future, we will find out whether the optimistic observations mainly in short-term studies will also be effective and applicable in broad practice.
老花眼是一种逐渐丧失适应能力的生理过程,它会导致视觉聚焦不同距离物体的能力下降。现在认为这是两个原因的直接结果:透明透镜的设计和它必须改变形状才能聚焦的方式,以及蛋白质在很长一段时间内的不稳定性。近年来,各种物质暂时缩小瞳孔,造成针孔效应,已被深入研究,以提高近视力。最常见的是1.25%的匹罗卡品溶液。这种物质本身已经有100多年的历史了,有充分的证据表明它具有降压作用和许多副作用。然而,浓度的降低和剂量的减少,以及目前正在研究的抗炎药物的加入,为治疗老花眼提供了希望。到目前为止,这些研究的结果是有希望的。研究人员指出,近视力得到改善,轻微副作用的发生率也很低。在未来,我们将发现主要在短期研究中的乐观观察是否也有效并适用于广泛的实践。
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引用次数: 0
Hyperreflective dots in optical coherence tomography 光学相干层析成像中的超反射点
Pub Date : 2022-09-30 DOI: 10.24292/01.ot.300922.1
K. Paczwa, Paulina Szabelska, M. Rerych, R. Różycki, J. Gołębiewska
Optical coherence tomography is a non-invasive and repeatable imaging method of posterior segment of the eye used in medical practice. Hyperreflective dots visible in OCT scans have been reported in various retinal diseases such as age-related macular degeneration, diabetic macular edema, retinal vein occlusion and central serous chorioretinopathy. In the future, HRDs may become a useful biomarker in making treatment decision and monitoring ocular conditions among the patients with mentioned diseases.
光学相干断层扫描是一种在医学实践中应用的无创、可重复的眼后段成像方法。在各种视网膜疾病如老年性黄斑变性、糖尿病性黄斑水肿、视网膜静脉阻塞和中枢性浆液性脉络膜视网膜病变中,OCT扫描可见高反射点。在未来,HRDs可能成为上述疾病患者治疗决策和监测眼部状况的有用生物标志物。
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引用次数: 0
The outcome of ciliary body ablation with diode laser contact transscleral cyclophotocoagulation in 6 months follow-up. 经巩膜激光接触睫状体消融6个月随访结果分析。
Pub Date : 2022-09-30 DOI: 10.24292/01.ot.300922.5
Weronika Mularska, A. Brązert, J. Kocięcki
The aim of the study is to analyse the postoperative results of continuous wave, transscleral cyclophotocoagulations (CW-TSCPC) in 6 months follow-up for patients with refractory glaucoma. Material and methods: We retrospectively reviewed 58 records of patients who underwent the transscleral cyclophotocoagulation because of refractory glaucoma at the Department of Ophthalmology, Poznan University of Medical Sciences, Poland, between 2016 and 2022. All patients underwent ophthalmological examination at baseline and during follow-up visits including best-corrected visual acuity, intraocular pressure measurement (IOP), slit-lamp examination, visual field and optical coherence tomography examination of the retinal nerve fiber layer (OCT RNFL). Follow-up time was 6 months. Results: We analyzed a group of 58 patients (28 women and 30 men, average age of 62). Majority of patients (41 eyes, 70.69%) had secondary open angle glaucoma. There were no serious complications of the CW-TSCPC procedure. We achieved IOP normalization (IOP below 22 mmHg) in 81.03% of eyes in 1 month follow-up, in 81.08% after 2 months, and in 72.41% after 6 months. Mean IOP reduction was 53.47%, 47.71%, and 47.65% from baseline at 1, 2, and 6 months, respectively. The number of medications taken by patients was lowered of 74.14%, 70.27% and 68.97% after 1, 2 and 6 months respectively. 17 eyes (29.31%) required additional surgical interventions within 6 months. Conclusions: CW-TSCPC is an effective and safe procedure. It allows lowering of IOP and reduction of drugs number administrated by patients with various types of glaucoma during 6 months follow-up. The procedure is technically easy and with well-controlled postoperative complications.
本研究的目的是分析难治性青光眼患者术后连续波经巩膜光凝治疗(CW-TSCPC) 6个月的随访结果。材料和方法:我们回顾性分析了2016年至2022年波兰波兹南医科大学眼科收治的58例难治性青光眼患者经巩膜光凝治疗的记录。所有患者在基线和随访期间均接受眼科检查,包括最佳矫正视力、眼内压测量(IOP)、裂隙灯检查、视野和视网膜神经纤维层光学相干断层扫描(OCT RNFL)。随访6个月。结果:我们分析了58例患者(女性28例,男性30例,平均年龄62岁)。继发性开角型青光眼占多数(41眼,70.69%)。CW-TSCPC手术无严重并发症。随访1个月后,81.03%的眼实现IOP正常化(IOP低于22 mmHg),随访2个月后达到81.08%,随访6个月后达到72.41%。在1、2和6个月时,平均IOP分别比基线降低53.47%、47.71%和47.65%。1个月、2个月和6个月后患者服药次数分别下降74.14%、70.27%和68.97%。17只眼(29.31%)在6个月内需要额外的手术干预。结论:CW-TSCPC是一种安全有效的手术方法。在6个月的随访中,不同类型青光眼患者可降低IOP,减少药物用量。手术技术简单,术后并发症控制良好。
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引用次数: 0
Obustronny przedni stożek soczewki w przebiegu zespołu Alporta – opis przypadku
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.070622
Ada Pandey, Justyna Gugnowska, Angelika Kruszyńska, Oliwia Cwalina, Kinga Czarnacka, Małgorzata Gawlak, A. Chmura, M. Kozak, Katarzyna Sajak-Hydzik, I. Pawlicka
Zespół Alporta jest chorobą genetyczną, która doprowadza nie tylko do przewlekłej choroby nerek, ale również do utraty słuchu i wzroku. W artykule został przedstawiony przypadek 34-letniego mężczyzny ze zdiagnozowanym przednim stożkiem soczewki w przebiegu zespołu Alporta. W związku z postępującym pogorszeniem widzenia i nieskutecznością doboru okularów pacjent został zakwalifikowany do zabiegu chirurgicznego. Przeprowadzono operację fakoemulsyfikacji zaćmy początkowej zniekształconych soczewek.
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引用次数: 0
Racjonalna terapia bakteryjnych zakażeń powierzchni oka z zastosowaniem fluorochinolonów
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.260522
Ewelina Trojacka, Justyna Izdebska
Prawidłowa powierzchnia oka ma szereg mechanizmów chroniących ją przed inwazją bakterii chorobotwórczych. W przypadku przełamania fizjologicznej bariery dochodzi do rozwoju zakażenia i stanu zapalnego. Jednymi z częstszych chorób zakaźnych powierzchni oka są bakteryjne zapalenia spojówek i rogówki. Terapia tych schorzeń powinna bazować na racjonalnym stosowaniu antybiotyków o szerokim spektrum działania przeciwbakteryjnego, wysoce skutecznych i bezpiecznych. Wszystkie powyższe cechy maja fluorochinolony: ofloksacyna, lewofloksacyna i moksyfloksacyna.
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引用次数: 0
Zmiana astygmatyzmu rogówkowego wraz z wiekiem
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.250622
Małgorzata Gawlak, Kinga Czarnacka, A. Chmura, Ada Pandey, Justyna Gugnowska, Angelika Kruszyńska, Oliwia Cwalina, Katarzyna Sajak-Hydzik, I. Pawlicka, M. Kozak
Praca ma charakter teoretyczny i powstała w celu sprawdzenia związku między zmianami astygmatyzmu a wiekiem. Analiza została przeprowadzona na podstawie dostępnych badań opisanych w literaturze przedmiotu. Zebrane dane statystyczne i informacje medyczne pozwalają na sformułowanie wniosku, że astygmatyzm może ulegać zmianie wraz z wiekiem. Zrealizowany projekt przedstawia wyniki, które posiadają zarówno wartość poznawczą, jak i aplikacyjną. Stwierdzone powiązania mogą być wykorzystane w praktyce lekarskiej pacjentów z niezbornością.
本文是理论性的,旨在检验散光变化与年龄之间的关系。分析基于文献中描述的现有研究。根据收集到的统计数据和医学信息,可以得出散光可能随年龄变化的结论。已完成的项目所得出的结果具有认知和应用价值。发现的相关性可用于非散光患者的医疗实践。
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引用次数: 0
The impact of various factors on the occurrence and type of visual experiences during the cataract surgery 各种因素对白内障手术中视觉体验的发生和类型的影响
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.200622
Zofia Kampka, Przemysław Urbaniec, Emila Senderek, D. Pojda-Wilczek
Aims: The aim was to check whether there is a relationship between ophthalmic and non-ophthalmic concomitant diseases and visual experiences during surgery. In addition, we wanted to verify whether visual experiences are influenced by such factors as age, gender, education, stress, etc. Methods: The patients phoned a few days after the surgery in order to be interviewed post-operatively by a 30-question questionnaire. Questions were asked on demographic data, concomitant diseases, both ophthalmic and non-ophthalmic, emotional and visual experiences during the cataract surgery p-value was calculated from the Chi-Square Test. Results: The study comprised 121 women and 87 men. 63.9% of patients underwent cataract surgery for the first time. Among 208 respondents 73 (35.1%) had light impressions and 77 (37%) reported visual impressions. Patients under 60 were more likely to experience both light and visual impressions (p < 0.05). Particular visual defects and concomitant diseases, both ophthalmic and non-ophthalmic, can influence the type of visual experiences. Stress was positively correlated with the occurrence of both light and visual impressions (p < 0.05) but it did not influence the exact type of visual experiences. For half of the respondents (51.0%), the impressions seen during the surgery were neutral. Only 14.4% of patients assessed these sensations as pleasant. Conclusion: Patients experienced a variety of visual sensations, which are not usually unpleasant, however they occurred more often among stressed patients and could also raise the stress level. Proper preoperative counselling is needed to help patients cope with the stress before surgery.
目的:目的是检查手术中眼科和非眼科伴发疾病与视觉体验之间是否存在关系。此外,我们想验证视觉体验是否会受到年龄、性别、教育程度、压力等因素的影响。方法:术后数天对患者进行电话随访,采用30题问卷进行随访。对白内障手术期间的人口统计资料、伴发疾病、眼科和非眼科、情感和视觉体验等问题进行询问,p值采用卡方检验计算。结果:该研究包括121名女性和87名男性。63.9%的患者为首次白内障手术。在208名受访者中,73人(35.1%)有轻微印象,77人(37%)有视觉印象。60岁以下的患者更有可能经历光和视觉印象(p < 0.05)。特殊的视觉缺陷和伴随的疾病,无论是眼性的还是非眼性的,都会影响视觉体验的类型。应激与光印象和视觉印象的发生均呈正相关(p < 0.05),但不影响视觉体验的确切类型。对于一半的受访者(51.0%),在手术中看到的印象是中性的。只有14.4%的患者认为这些感觉是愉快的。结论:患者有多种视觉感受,通常不令人不愉快,但在压力患者中发生的频率更高,并可能提高压力水平。术前需要适当的咨询,以帮助患者应对手术前的压力。
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引用次数: 0
Choosing the right surgical treatment for hyperopia 选择正确的远视手术治疗方法
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.120622
J. Grzeszkowiak, J. Wierzbowska
Several aspects make the treatment of hyperopia and selecting the treatment method challenging. This article has reviewed the main surgical options for hyperopia and factors that must be considered when choosing the right treatment. The modern refractive technology offers excellent options with the optimal choice of procedure being dependent on the level of refractive error, age of the patient and the unique anatomical factors in each case. Surgeons must perform a complete evaluation and risk-benefit assessment of the individual patient to select the best procedure.
几个方面使得远视的治疗和治疗方法的选择具有挑战性。本文综述了远视的主要手术选择和选择正确治疗时必须考虑的因素。现代屈光技术提供了极好的选择,最佳的手术选择取决于屈光不正的程度,患者的年龄和每个病例独特的解剖因素。外科医生必须对个体患者进行完整的评估和风险-收益评估,以选择最佳手术方案。
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引用次数: 0
Optic disc swelling in the paediatric population 小儿视盘肿胀
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.100622
Aleksandra Chrobak, Sylwia Burza-Grycz, A. Samsel
Swelling of the optic disc may result from inflammation, infiltration, optic nerve compression or ischaemia, as well as increased intracranial pressure. It can be imitated by local structural features of the optic disc leading to pseudopapilloedema. Disease entities leading to optic disc swelling can take different courses in the paediatric population compared to the adult population. Investigations used to confirm diagnosis include optical coherence tomography (OCT), ocular ultrasound, fluorescein angiography, visual evoked potentials (VEP), and imaging studies of head and orbits.
视盘肿胀可由炎症、浸润、视神经受压或缺血以及颅内压升高引起。视盘局部结构特征可导致假性乳头水肿。与成人相比,导致视盘肿胀的疾病实体在儿科人群中可以采取不同的疗程。用于确认诊断的检查包括光学相干断层扫描(OCT)、眼超声、荧光素血管造影、视觉诱发电位(VEP)以及头部和眼眶成像研究。
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引用次数: 0
Katy kappa i alfa w diagnostyce przedoperacyjnej pacjentów nadwzrocznych kwalifikowanych do wszczepienia soczewki wieloogniskowej z uzyciem technologii iTrace
Pub Date : 2022-06-30 DOI: 10.24292/01.ot.010622
Adam Cywiński, Olaf Szyja
Ocenie poddano wielkości oraz lokalizacje katów kappa (κ) i alfa (α) w oczach ze stwierdzona nadwzrocznością, kwalifikowanych do wszczepienia soczewek klasy premium. Badaniem objęto 67 pacjentów, 101 oczu w zakresie wady nadwzroczności od +0,5 Dsph do +10,62 Dsph. Zarówno w przypadku kątów α, jak i κ najczęstsza lokalizacja to kwadranty skroniowe dolne, a w następnej kolejności skroniowe górne. Stwierdzono statystycznie znamienną zależność między wielkością kątów α oraz κ a wielkością wady nadwzroczności. Badanie wielkości kątów wykonano w każdym przypadku z użyciem analizatora iTraceTM
该研究评估了符合优质人工晶体植入条件的已知远视眼的卡帕(κ)和α(α)阴极的大小和位置。该研究包括 67 名患者,101 只眼睛的远视度数缺陷范围为 +0.5 Dsph 至 +10.62 Dsph。对于α角和κ角,最常见的位置是颞下象限,其次是颞上象限。α角和κ角的大小与远视缺损的大小之间有明显的统计学关系。使用 iTraceTM 分析仪对每个病例的角度大小进行测试
{"title":"Katy kappa i alfa w diagnostyce przedoperacyjnej pacjentów nadwzrocznych kwalifikowanych do wszczepienia soczewki wieloogniskowej z uzyciem technologii iTrace","authors":"Adam Cywiński, Olaf Szyja","doi":"10.24292/01.ot.010622","DOIUrl":"https://doi.org/10.24292/01.ot.010622","url":null,"abstract":"Ocenie poddano wielkości oraz lokalizacje katów kappa (κ) i alfa (α) w oczach ze stwierdzona nadwzrocznością, kwalifikowanych do wszczepienia soczewek klasy premium. Badaniem objęto 67 pacjentów, 101 oczu w zakresie wady nadwzroczności od +0,5 Dsph do +10,62 Dsph. Zarówno w przypadku kątów α, jak i κ najczęstsza lokalizacja to kwadranty skroniowe dolne, a w następnej kolejności skroniowe górne. Stwierdzono statystycznie znamienną zależność między wielkością kątów α oraz κ a wielkością wady nadwzroczności. Badanie wielkości kątów wykonano w każdym przypadku z użyciem analizatora iTraceTM","PeriodicalId":112284,"journal":{"name":"OphthaTherapy. Therapies in Ophthalmology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126709057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
OphthaTherapy. Therapies in Ophthalmology
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