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Management of lower limbs leiomyosarcoma: A case report 下肢平滑肌肉瘤的治疗1例
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000119
Cuenca-Gonzalez Concepcion, Berzal Cantalejo Maria Fernanda, Herranz-Torrubiano Ana Maria, Lucia Vaamonde Lorenzo
We report the case of a woman referred to our rehabilitation department who presented a soft tissue tumour, a proximal third tibia leiomyosarcoma. It’s analyzed how the diagnosis was made, the treatment for tumour and its sequelae and the follow up period, by doing an update of the scientific evidence in this tumour management. This tumour is a subtype in soft tissue sarcomas. These are rare tumours that arise mostly from mesenchymal tissues and leiomyosarcoma is the fourth in frequency (12%). Although they can appear in any location, 40% cases have their origin typically in extremities. Sarcomas in extremities are characterized by a painless mass, incidentally discovered by the patient, the doctor or by performing an ultrasound. Conservative surgery is considered the main treatment for this soft tissue sarcoma, avoiding radical surgeries which don’t achieve survival results. Radiotherapy and adjuvant chemotherapy are used both with surgery to prevent local recurrence and metastases. Pathology and imaging tests (ultrasounds, CT and MRI) will be fundamental for the staging, for therapeutic decisions to be made and for monitoring possible local recurrences or regional or systemic metastases. Correspondence to: Cuenca-González Concepción, Universidad Complutense, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Physical Medicine and Rehabilitation Service, Hospital Clínico San Carlos, Madrid, Spain, Tel: +34 91 330 36 03; E-mail: cuchacuenca@gmail.com
我们报告的情况下,一名妇女转介到我们的康复部门谁提出了软组织肿瘤,近第三胫骨平滑肌肉瘤。它分析了如何做出诊断,肿瘤的治疗及其后遗症和随访期,通过更新肿瘤管理的科学证据。这个肿瘤是软组织肉瘤的一个亚型。这是一种罕见的肿瘤,主要发生在间质组织中,平滑肌肉瘤的发病率排名第四(12%)。尽管它们可以出现在任何部位,但40%的病例通常起源于四肢。四肢肉瘤的特点是无痛肿块,由病人、医生偶然发现或通过超声检查发现。保守手术被认为是这种软组织肉瘤的主要治疗方法,避免根治性手术,根治性手术不能达到生存效果。放疗和辅助化疗与手术同时使用,以防止局部复发和转移。病理和影像学检查(超声、CT和MRI)将是分期、治疗决策和监测可能的局部复发或区域或全身转移的基础。通信:Cuenca-González Concepción,康普顿斯大学医学院,物理医学和康复系,物理医学和康复服务,Clínico圣卡洛斯医院,马德里,西班牙,电话:+34 91 330 36 03;电子邮件:cuchacuenca@gmail.com
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引用次数: 0
Brain tumor identification from MRI imaging using fuzzy inference 基于模糊推理的MRI脑肿瘤识别
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000131
Bouharati Imene, Babouche Farid, Bouharati Khaoula, Khenchouche Abdelhalim, Bouharati Saddek
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引用次数: 2
The patterns of ordering Computed Tomography Pulmonary Angiogram (CTPA) for diagnosis of pulmonary embolism (PE) in a rural health setting 在农村卫生机构订购计算机断层扫描肺血管造影(CTPA)诊断肺栓塞(PE)的模式
Pub Date : 2018-01-01 DOI: 10.15761/rdi.1000127
Alshehri Am, Srinivasan, Umair Khan, S. Wickremasena, Hui Jh, Lee Gs, A. Bhattacharya
Background: Pulmonary embolism (PE) is a life-threatening condition with overall mortality of up to 20 % when left untreated. CTPA is the preferred investigation for diagnosis of PE for patients with normal kidney function. Several studies showed this test is being over employed without using available predictive tools i.e. Wells score, Modified Geneva score & D-Dimer Methodology: A retrospective review of patients’ records who had CTPA for suspected pulmonary embolism from the period of 1st March 2015 to 28th Feb 2016. Patient’s demographics and components of different scoring system were obtained by manual review of patient’s electronic records. Result: A total of 249 CTPAs were done during this study period. In term of patient demographics, median age was 63 years and 48.6 % of patients were females. PE was diagnosed in 34 (13.7%) patients. Only 196 (76.6%) patients had a CXR as an initial investigation. Acute kidney injury was noted in 23 (14.0%) patients post CTPA. Revised Geneva score was calculated for all patients who had CTP for PE, only 10 (4 %) patients had a high probability on Revised Geneva score (score >11). Wells score could not be accurately calculated due to the retrospective nature of the study. Conclusion: The diagnostic yield of CTPA with a positive result for pulmonary embolism was 13.7%, which is below the recommended standards by the Royal College of Radiology (UK) (15.4% to 37.4%). Also, these findings were noted to be inferior compared with a similar study done in an Australian hospital. These findings may be attributed to the poor utilization of risk assessment tools (Geneva, Wells and D-Dimer) and not performing simple chest X-ray prior to CTPA. A protocol to request CTPAs is needed which is suited to the regional settings to avoid unnecessary CTPAs and its complications. Correspondence to: Al Alawi AM, Department of Medicine, Goulburn Valley Health, Australia, E-mail: dr.abdullahalalawi@gmail.com Received: March 03, 2018; Accepted: March 20, 2018; Published: March 24, 2018 Introduction Pulmonary embolism (PE) is a potentially fatal condition if left untreated. The annual crude incidence rate of PE in Australian was estimated to be 0.31 per 1000 in a community setting [1]. The 1-year case-fatality rate for PE is approximately 23% [2]. Efficient clinical evaluation and diagnostic testing is necessary to avoid delays in initiating therapy, which in turn reduces morbidity and mortality from PE [3]. Pulmonary angiography is the historical criterion standard for the diagnosis of PE, which has now been largely replaced by less invasive alternatives. CTPA is the investigation of choice for diagnosis of PE but requires the use of potentially nephrotoxic contrast agents and radiation [4,5]. Alternatively, as a result V/Q scans are commonly considered in patients with renal impairment, pregnant women and in young patients due to the lower dose of radiation [6]. Over the last decade, there has been a significant increase in CTPA
背景:肺栓塞(PE)是一种危及生命的疾病,如果不及时治疗,总死亡率高达20%。对于肾功能正常的患者,CTPA是诊断PE的首选方法。几项研究表明,该测试被过度使用,而没有使用可用的预测工具,即Wells评分、修改日内瓦评分和D-Dimer方法:对2015年3月1日至2016年2月28日期间因疑似肺栓塞而进行CTPA的患者记录进行回顾性审查。通过人工查阅患者电子病历,获得患者的人口统计资料和不同评分系统的组成部分。结果:本研究期间共完成ctpa 249例。患者年龄中位数为63岁,女性占48.6%。34例(13.7%)患者被诊断为PE。只有196例(76.6%)患者进行了CXR作为初步调查。23例(14.0%)患者在CTPA后出现急性肾损伤。对所有接受CTP治疗的PE患者计算修订日内瓦评分,只有10例(4%)患者的修订日内瓦评分高概率(评分>11)。由于研究的回顾性性质,Wells的评分无法准确计算。结论:CTPA对肺栓塞的阳性诊断率为13.7%,低于英国皇家放射学院推荐的标准(15.4% ~ 37.4%)。此外,与澳大利亚一家医院进行的类似研究相比,这些发现被认为是低劣的。这些发现可能是由于风险评估工具(Geneva, Wells和D-Dimer)的使用不当以及在CTPA之前没有进行简单的胸部x线检查。为避免不必要的ctpa及其并发症,需要制定适合区域环境的ctpa请求协议。通讯:Al Alawi AM,医学部,Goulburn Valley Health, Australia, E-mail: dr.abdullahalalawi@gmail.com收稿日期:2018-03-03;录用日期:2018年3月20日;如果不及时治疗,肺栓塞(PE)是一种潜在的致命疾病。据估计,澳大利亚社区PE的年粗发病率为0.31 / 1000[1]。PE的1年病死率约为23%[2]。有效的临床评估和诊断测试是必要的,以避免延迟开始治疗,从而降低PE的发病率和死亡率[3]。肺血管造影是PE诊断的历史标准,现在已被侵入性较小的替代方法所取代。CTPA是诊断PE的首选检查,但需要使用潜在肾毒性造影剂和放疗[4,5]。另外,由于辐射剂量较低,肾损害患者、孕妇和年轻患者通常考虑进行V/Q扫描[6]。在过去十年中,CTPA在PE诊断中的应用显著增加[7]。不适当的CTPA使用会增加医疗保健支出,并有可能给患者造成不必要的伤害,如造影剂肾病和超敏反应[8]。CTPA对PE的阳性率可低至7%,但使用检测前风险评估工具可将该阳性率提高至30%以上[9-11]。常用的分层工具是Wells评分和修订后的Geneva评分[12]。根据肺栓塞的危险因素,将患者分为低(Geneva评分0-3分,Wells评分0-1分)、中(Geneva评分4-10分,Wells评分2-6分)和高(Geneva评分≥11分,Wells评分≥7分)三组[13]。d -二聚体值在低/中概率组中是一个非常有用的标记,其使用已在若干研究中得到验证[12]。在一般人群中,d -二聚体检测和临床评估工具相结合的pe漏报率不到2%[14]。本次审核的目的是:1)评估区域卫生机构CTPA对PE的适当使用(过度使用/使用不足)和CTPA阳性结果的比率。2)检查使用CTPA进行PE的现有算法的遵守程度。3)估计造影剂肾病的发生率。Al Alawi AM(2018)计算机断层扫描肺血管造影(CTPA)在农村卫生机构肺栓塞(PE)诊断中的应用模式vol . 2(2): 2-3 Radiol diagol Imaging, 2018 doi: 10.15761/RDI.1000127Goulburn Valley Health是一家乡村医院,位于墨尔本东北200公里处,为从大谢泼顿市延伸到新南威尔士州南部的集水区人口约12万人提供医疗服务。医学影像提供多种服务,包括CT扫描和核医学。
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引用次数: 0
Moyamoya syndrome concomitant with hyperhomocysteinemia and a Methylenetetrahydrofolate reductase gene mutation: a case report and brief review 烟雾综合征合并高同型半胱氨酸血症和亚甲基四氢叶酸还原酶基因突变:一例报告和简要回顾
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000130
Abreu Montanaro Vv, Marinho Pb, Uchoa Cavalcanti Eb, Ferreira Martins Bja, C. Ap
The role of hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) gene mutation in the pathogenesis of ischemic stroke has been a topic of growing interest. Reports available in literature describe this association, primarily in cases of pediatric stroke. We report a case of a 23-year-old woman presented to the SARAH Network of Rehabilitation Hospitals with a history of recurrent ischemic strokes during infancy and an etiological diagnosis of Moyamoya syndrome. Evaluation revealed mild elevation of serum homocysteine levels and a homozygous MTHFR gene mutation, no other associated abnormalities were detected. There is evidence of the presence of these abnormalities in some cases of pediatric ischemic stroke in the clinical setting. Data are limited regarding the role of hyperhomocysteinemia and an MTHFR gene mutation in causing vascular lesions/damage. Further studies involving patients with ischemic stroke (primarily those with arterial occlusion), are warranted to better establish such a correlation. *Correspondence to: Abreu Montanaro VV, Neurological Rehabilitation Department, Sarah Hospital, Brasília Brazil, Tel: +55 61 33191111; E-mail: vinicius_montanaro@yahoo.com.br Received: March 05, 2018; Accepted: March 27, 2018; Published: March 31, 2018 Introduction Data available in literature describe an association between hyperhomocysteinemia and a methylenetetrahydrofolate reductase (MTHFR) gene mutation and vascular events [1]. A possible correlation is known to exist between 677TT MTHFR gene polymorphism and the presence of large-vessel lesions [2] and Moyamoya syndrome. However, the correlation between the 677TT gene polymorphism and Moyamoya syndrome is not conclusive [3]. In the present paper, we report the case of a patient who presented with Moyamoya syndrome associated with hyperhomocysteinemia and a MTHFR gene mutation.
高同型半胱氨酸血症和亚甲基四氢叶酸还原酶(MTHFR)基因突变在缺血性卒中发病机制中的作用已成为人们越来越感兴趣的话题。文献报道描述了这种关联,主要是在小儿中风病例中。我们报告一例23岁的妇女提出SARAH网络康复医院的历史复发性缺血性中风在婴儿期和烟雾综合征的病因学诊断。评估显示血清同型半胱氨酸水平轻度升高和纯合子MTHFR基因突变,未检测到其他相关异常。有证据表明,这些异常的存在,在一些儿科缺血性中风的情况下,在临床设置。关于高同型半胱氨酸血症和MTHFR基因突变在引起血管病变/损伤中的作用的数据有限。对缺血性脑卒中患者(主要是动脉闭塞患者)的进一步研究有必要更好地建立这种相关性。*通信:Abreu Montanaro VV,神经康复科,萨拉医院,Brasília巴西,电话:+55 61 33191111;邮箱:vinicius_montanaro@yahoo.com.br收稿日期:2018年03月05日;录用日期:2018年3月27日;文献资料描述了高同型半胱氨酸血症与亚甲基四氢叶酸还原酶(MTHFR)基因突变和血管事件[1]之间的关联。已知677TT MTHFR基因多态性与大血管病变[2]和烟雾综合征之间存在可能的相关性。然而,677TT基因多态性与烟雾综合征之间的相关性尚无定论[0]。在本文中,我们报告了一例患者谁提出烟雾综合征与高同型半胱氨酸血症和MTHFR基因突变。
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引用次数: 0
Importance of magnetic resonance imaging in the diagnosis of breast hamartoma 磁共振成像在乳腺错构瘤诊断中的重要性
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000136
A. A, Arslan Fz, Eryilmaz Ma, Oner O
Aim: Hamartomas are benign breast lesions. Radiologic and clinical evaluation has great importance in the diagnosis for reducing unnecessary procedures. We intend to investigate the contribution of magnetic resonance imaging (MRI) in the diagnosis of hamartomas Method: Our research has been conducted retsospectively, a total of 55 breast hamartomas were reassessed using mammography (MG) and MRI. In the detection of morphological features of hamartomas were compared efficacy of MG and MRI. ADC values were obtained corresponding to lesion localization and normal breast parenchyma. Result:MRI was significantly superior to MG in detecting pesudo-capsule and size(p<0,001). There was no significant difference between enhancement pattern and ADC values obtained from breast tissue and hamartoma. Conclusion: Conclusionally, we assume that MRI can provide more detailed information in difficult cases which have not classical mammographic appearances, so MRI can be considered as an alternative imaging for accurate diagnosis and prevent unnecessary biopsies and surgeries. *Correspondence to: Arslan FZ, Konya Training and Research Hospital, Department of Radiology, Haci Saban Mah, Meram New Road Avenue, Meram, Konya, Turkey, Tel: 05064382430; Fax: 03323236723; E-mail: Zeynep_a1002@hotmail.com
目的:错构瘤是乳腺良性病变。放射学和临床评估在诊断中具有重要意义,可以减少不必要的手术。方法:回顾性研究了55例乳腺错构瘤患者,采用乳腺x线摄影(MG)和MRI对其进行重新评估。比较MG和MRI对错构瘤形态学特征的检测效果。ADC值与病变定位及正常乳腺实质相对应。结果:MRI对假包膜及大小的检测明显优于MG (p< 0.001)。乳腺组织和错构瘤的增强模式和ADC值无显著差异。结论:综上所述,我们认为MRI可以为没有经典乳房x线检查表现的疑难病例提供更详细的信息,因此MRI可以作为准确诊断的替代成像,避免不必要的活检和手术。*通信:Arslan FZ,科尼亚培训和研究医院放射科,Haci Saban Mah, Meram新路大道,土耳其科尼亚,Meram, Meram, Tel: 05064382430;传真:03323236723;电子邮件:Zeynep_a1002@hotmail.com
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引用次数: 0
Medical radiation exposure of pregnant patients: case study of the gynaeco obstetric and paediatric hospital of douala, cameroon 怀孕病人的医疗辐射暴露:喀麦隆杜阿拉妇产科和儿科医院个案研究
Pub Date : 2018-01-01 DOI: 10.15761/rdi.1000126
A. Simó, Ateba Jfb, Manyol En, Ndah Tn, Ndontchueng Mm, Njiki Cd
The use of X-Ray in medical radiology is always risky. In particular, when it comes to imaging pregnant women, the majority of foetus cells might be damaged. Despite all the requirements from international renowned organizations relating to imaging of pregnant women and newborns, the unintentional irradiations of the foetus are still common in radiology services. A case that occurred at the Gynaeco Obstetric and Paediatric Hospital of Douala (Cameroon) in September 2015, is instructive. A 46-year-old woman about six months pregnant was subject to an X-Ray of the pelvis requested by a medical doctor following a suspicion “of osteonecrosis”. Investigations have been conducted by the National Radiation Protection Agency (NRPA) by using Diavolt kVp meter. In addition, theoretical foetal dose estimation has been proceeded to evaluate accuracy of the technical estimation of the obtained result. The patient was irradiated with parameters of 20 mAs and 90 kV which lead to a dose to foetus of about 213 μGy. The lead apron that was used to protect the pelvis reduced the absorbed dose by a factor of 6. The hospital officials were advised to do more collaboration between referral medical doctors and radiologists as soon as the use of X-Ray on pregnant women is deemed necessary, to inform patients about the dangers of ionizing radiation on foetus, and to request information on their pregnancy status as well. Correspondence to: Beyala Ateba JF, National Radiation Protection Agency of Cameroon, Yaoundé, Cameroon, E-mail: bajeanfelix@yahoo.fr Received: March 03, 2018; Accepted: March 20, 2018; Published: March 24, 2018 Introduction The use of X-ray generators for diagnostic radiology in the medical sector in Cameroon, Central Africa, is wide spread and on the increase in recent times [1]. One of the most commonly asked questions in relation to the use of ionizing radiation in medicine concerns the management of the pregnant patient. Instinctively, one might want to avoid use of radiation with a pregnant patient; however, there are a number of situations in which the use of radiation for diagnosis or therapy is appropriate. In addition, there are many female physicians and technicians who are employed in medical settings involving radiation. Thousands of pregnant patients and radiation workers are exposed to ionizing radiation each year [2]. X rays have also been used for more than 50 years to assess the dimensions of the maternal pelvis in pregnancy [3]. For occupationally exposed pregnant women, the equivalent dose to the surface of the abdomen shall not exceed 2 mSv per year and the effective dose resulting from exposure shall not exceed 1 mSv from the time which the pregnancy is known until its term [4,5]. According to presidential decree N° 2002/250, issued on 31st October 2002, National Radiation Protection Agency (NRPA), was established as the only Regulatory Body in Cameroon [6]. It is the competent authority for radiation protection and waste management
在医学放射学中使用x射线总是有风险的。特别是,当对孕妇进行成像时,大多数胎儿细胞可能会受损。尽管国际知名组织对孕妇和新生儿的成像有各种要求,但在放射学服务中,对胎儿的意外照射仍然很常见。2015年9月发生在杜阿拉(喀麦隆)妇产科和儿科医院的一个病例具有指导意义。一名怀孕约6个月的46岁妇女因怀疑"骨坏死",在医生的要求下接受了骨盆x光检查。美国国家辐射防护署(NRPA)使用Diavolt kVp计进行了调查。此外,还进行了理论胎儿剂量估计,以评价所得结果的技术估计的准确性。患者接受20 ma和90 kV的辐照,对胎儿的辐照量约为213 μGy。用于保护骨盆的铅围裙将吸收剂量降低了6倍。建议医院官员在认为有必要对孕妇使用x射线时,在转诊医生和放射科医生之间进行更多的合作,告知患者电离辐射对胎儿的危险,并要求提供有关其怀孕状况的信息。通讯:Beyala Ateba JF,喀麦隆国家辐射防护机构,yaound<e:1>,喀麦隆,E-mail: bajeanfelix@yahoo.fr收稿日期:2018年03月03日;录用日期:2018年3月20日;简介在中非喀麦隆的医疗部门,x射线发生器用于诊断放射学的使用非常广泛,并且近年来呈上升趋势。关于在医学中使用电离辐射,最常被问到的问题之一是对怀孕病人的管理。出于本能,人们可能会想避免对孕妇使用辐射;然而,在一些情况下,使用辐射进行诊断或治疗是合适的。此外,还有许多女医生和技术人员受雇于涉及辐射的医疗机构。每年有成千上万的孕妇和辐射工作者暴露在电离辐射下。50多年来,X射线也被用于评估孕妇骨盆的尺寸。对于职业性暴露的孕妇,从知道怀孕到足月,每年腹部表面的等效剂量不应超过2毫西弗,暴露产生的有效剂量不应超过1毫西弗[4,5]。根据2002年10月31日发布的第2002/250号总统令,成立了国家辐射保护局(NRPA),作为喀麦隆唯一的监管机构。是主管辐射防护及废弃物管理之主管机关。在此框架下,NRPA授权并控制电离辐射源的使用,以保护人类和环境免受辐射的有害影响。自从第2002/250号法令第4(5)条规定国家原子能机构负责应对放射性事故/事件以来,它已经收到了喀麦隆杜阿拉妇产科和儿科医院发生的与x光机照射胎儿有关的放射性事件的通知。根据这一通知,NRPA小组开展了一项调查任务,以估计对胎儿的剂量。本文给出了相关事件管理的操作措施。这些措施将在喀麦隆整个医疗部门共享,以避免类似情况发生。根据ICRP第84号出版物,NRPA制定了一些措施来管理诊断放射学中的怀孕患者。在x线检查之前,应确定患者是否怀孕或可能怀孕,以及胎儿是否会在直射光束中。此外,应在x射线诊断部门和使用x射线诊断设备的区域内的几个地方张贴咨询通知,以避免胚胎和胎儿的无意辐射暴露。当一个病人被确定怀孕或可能怀孕时,放射科医生通常首先确定胎儿是否会出现在初级x射线束中。如果没有,那么胎儿的风险就极低,最重要的是在得到正确诊断的同时,尽量减少接触的次数和类型。当检查表明x射线束直接照射胎儿时,这不能推迟到Simo A(2018年)怀孕患者的医疗辐射暴露:喀麦隆杜阿拉妇产科和儿科医院的案例研究第2卷(2):2-4放射诊断成像,2018年doi: 10。 15761 / RDI。1000126怀孕,最常见的方法来定制检查和减少胎儿暴露是准直光束到一个非常具体的兴趣区域。当进行高剂量手术时,当已知胎儿处于主x射线束中时,应记录技术因素,以便随后对胎儿剂量进行估计。实验胎儿剂量估计采用NRPA调查方案测量孕妇皮肤入口剂量(ESD)。根据Mahadevappa 2011年的研究,保守估计胎儿剂量为常规x线摄影和透视技术的入口皮肤剂量(ESD)的0.15倍。DIAVOLT kVp-meter是用于x射线诊断设备验收测试和质量控制(QC)的无创kVp, PPV,剂量和时间计。根据NRPA指南N°0050(2016)关于诊断放射学x光机质量控制的要求,遵循以下步骤。已选择RAD/FLU模式;kVp设定范围为40 ~ 150kv;已选择滤管上显示的2.5 mmAl过滤;DIAVOLT kVp计放置在工作台顶部距x射线管100 cm处;光场对准DIAVOLT的大小;试验选用20ma和90kv;记录了三个ESD测量值。DIAVOLT kVp计被0.25 mmPb的铅圈覆盖,以再现检查条件,其物理参数如下:源到图像受体的距离为1米;管电位设定为90kv;管电流设定200ma;曝光时间0.1秒;梁尺寸:43厘米x 35.5厘米;患者AP厚度26 cm;总过滤2.5毫摩尔。理论胎儿剂量估计提供胎儿剂量估计的准确方法,无论是前瞻性的还是回顾性的,都是使用用于患者检查的技术参数并考虑胎儿深度和大小bbb来评估个体患者的剂量。要求以下参数的具体值:每次检查的投影和视图,过滤,源到成像仪受体的距离,机器输出,以及用于检查的技术参数(kVp,管电流,曝光时间等)。根据NCRP报告54,估计放射检查对胚胎-胎儿的剂量所需的基本信息是某参考点的空气暴露率和半值层(HVL)[10]。从Schulz和Gignac(1976)的三相设备[11]的数据中可以得到空气中估计的暴露率(mR/mAs)作为距离x射线源1米处kVp和总铝过滤的函数。如果总过滤是已知的,则可以从1968年发表的NCRP报告33中估计三相和恒电位设备[12]的HVL。空气中的暴露率可以用平方反比外推法在源肤距离(SSD)上确定。表1显示了用带铅圈的diavt kVp计测量的剂量。其平均值约为1420 μGy。这个值被用来估计胎儿吸收剂量,根据Mahadevappa在2011年发现的213 μGy。通过无铅围圈和有铅围圈的Diavolt测量的剂量之比,对铅围圈的屏蔽效果进行了评价。因此,用于覆盖骨盆的屏蔽将直接光束衰减了约6倍。根据距离x射线源1m处空气中暴露率的Schulz和Gignac曲线收集的数据,以及NCRP报告33中HVL作为三相发生器管电位的函数估计的数据,考虑x射线源的特性(表3)和暴露参数,得到表2。总暴露在1米是由以下关系:总暴露在1 m(先生)=报(mAs)××先生numberofexposure曝光率在空气中()mAs(1)暴露在空气源(SSD)是由皮肤距离:2总暴露在1 m暴露在空气SSD = SSD(2)此外,子宫的剂量每伦琴暴露皮肤据估计通过剂量子宫1伦琴入口的皮肤接触Rosenstein(1976)数据报告摘要NCRP 54[13]。根据上述程序,已发现子宫的理论剂量为1.8毫戈瑞。由于用于检查的铅围裙将吸收剂量降低了6倍,因此可以假设胎儿接受的剂量约为300 μGy。对胎儿剂量进行了理论估计,以评价实验胎儿剂量估计的准确性。结果与理论所得结果列于表4。胎儿剂量估计值在29%以内一致。根据ICRP 84,胚胎或胎儿从普通膜吸收剂量的估计
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引用次数: 0
The usefulness of preoperative MRI in synchronous bilateral breast cancer 同时性双侧乳腺癌术前MRI检查的价值
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000122
Y. Kosaka, Mariko Kikuchi, Norihiko Sengoku, Y. Tanaka, Mina Waraya, H. Katoh, K. Yamashita, Sabine Kajita, R. Woodhams, M. Watanabe
Background: The incidence of synchronous bilateral breast cancer is increasing each year. The applicability of contrast-enhanced magnetic resonance imaging (MRI) in the detection of multiple breast lesions has been reported in many studies. However, there have been no reports concerning the usefulness of preoperative MRI to evaluate synchronous bilateral breast cancer in Japan. We reviewed patients with synchronous bilateral breast cancer to investigate the applicability of contrastenhanced MRI in detecting contralateral breast cancer that was not visible by MMG or ultrasound. Methods: Synchronous bilateral breast cancer was found in 47 (3.2%) of the 1465 breast cancer patients who underwent surgery in our hospital between April 2006 and December 2012. Of those 47 patients, we enrolled 28 patients whose second lesions were non-palpable. The sensitivities of MMG, ultrasonography, and contrastenhanced MRI were compared for their ability to detect the malignancy of the second lesion. We also assessed the pathological characteristics of those lesions that were only visible by contrast-enhanced MRI. Results: In 28 patients whose second lesions were non-palpable,7% was DCIS in first lesions, and 39% was DCIS in second lesions. The median size of the invasive cancer was 2.3 cm (range, 0.5-9.5 cm) within the first lesions. The median size of the invasive cancer was 1.0 cm (range, 0.4-5.0 cm) within the second lesions. Of the 28 malignant lesions, 13 (46%) were positive by MMG, 18 (64%) were positive by ultrasonography, and 28 (100%) were positive by contrast-enhanced MRI. In six of the 28 patients (21%), the malignant lesions were found by contrast-enhanced MRI but not by MMG nor by ultrasonography. Conclusion: Contrast-enhanced MRI has the highest sensitivity and is therefore the most useful modality in identifying non-palpable breast abnormalities. It is especially useful in the detection of small contralateral lesions and lesions immediately under the nipple of the contralateral breast. Correspondence to: Yoshimasa Kosaka, Department of Surgery, School of Medicine, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan; Tel: +81 427788111, Fax: +81 427789556; E-mail: y-kosaka@med.kitasato-u.ac.jp
背景:双侧乳腺癌的发病率逐年上升。许多研究报道了对比增强磁共振成像(MRI)在乳腺多发病变检测中的适用性。然而,在日本还没有关于术前MRI评估同步双侧乳腺癌有效性的报道。我们回顾了同步双侧乳腺癌患者,探讨对比增强MRI在检测MMG或超声未见的对侧乳腺癌中的适用性。方法:2006年4月至2012年12月我院收治的1465例乳腺癌患者中,发现双侧同步乳腺癌47例(3.2%)。在这47例患者中,我们招募了28例第二病变不可触及的患者。比较MMG、超声检查和MRI增强检查对第二病变的敏感性。我们还评估了那些仅通过增强MRI可见的病变的病理特征。结果:28例第二病变不可触及的患者中,7%为第一病变DCIS, 39%为第二病变DCIS。浸润性癌的中位尺寸为2.3 cm(范围0.5-9.5 cm)。浸润性肿瘤的中位尺寸为1.0 cm(范围0.4-5.0 cm)。28例恶性病灶中MMG阳性13例(46%),超声检查阳性18例(64%),MRI增强检查阳性28例(100%)。在28例患者中,有6例(21%)的恶性病变是通过磁共振造影发现的,而不是通过MMG或超声检查发现的。结论:对比增强MRI具有最高的敏感性,因此是识别不可触及的乳房异常的最有用的方式。它在检测小的对侧病变和对侧乳房乳头下的病变时特别有用。通讯对象:日本神奈川县相模原市南区北中1-15-1北中大学医学院外科学科小坂良正;电话:+81 427788111,传真:+81 427789556;电子邮件:y-kosaka@med.kitasato-u.ac.jp
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引用次数: 2
Dual Energy CT - A diagnostic boon 双能量CT -诊断的福音
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000125
ALMohammad Ma, H. Hao, L. Bo, Bin Sh
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引用次数: 2
Ameboma versus colorectal cancer: a case report 阿米巴肿与结直肠癌:1例报告
Pub Date : 2018-01-01 DOI: 10.15761/rdi.1000128
F. Uccelli, A. Intelisano, D. Piccinali, A. Zanello, R. Meroni, L. Pedone, N. Gaffuri, O. Goletti
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引用次数: 0
A case of major lung herniation with minor trauma 重度肺疝伴轻微创伤1例
Pub Date : 2018-01-01 DOI: 10.15761/RDI.1000140
Carvalho Am, Anderson Da
We present a case of significant lung herniation which was related to a relatively low acuity injury sustained while moving a small load of bricks. The patient was symptomatic with pain and dyspnea, and chest images revealed a large herniation of the right lower lobe through a defect in the intercostal muscles. Lung herniation is rare but is usually associated with significant trauma or surgery. This degree of injury occurred with minor provocation but caused significant morbidity. *Correspondence to: Carvalho AM, Queen’s University Belfast School of Medicine, UK, E-mail: Paula.Carvalho@med.va.gov Received: June 15, 2018 Accepted: June 25, 2018; Published: June 28, 2018 Case report A 62-year-old man presented to the emergency room with swelling and pain at his right lower costal margin. A sharp tearing pain was reported at the initial injury which occurred while moving bricks 2 days prior. Several hours later, the patient, who is a smoker, had a coughing episode with aggravation of the pain and subsequent development of a soft spongy bulge at the site. The bulge increased in size with subsequent coughing and became severely painful, preventing normal tidal breaths. The patient reduced the swelling by external compression with a broad belt which he wore in order continue working. Although compression was helpful, he was unable to continue work due to intractable pain. On physical exam, the patient was alert and in no immediate distress. He had a 30 pack-year history of cigarette smoking but was otherwise in good health and used no medications. Vital signs were normal, except for a respiratory rate at 22/minute with shallow breaths. The patient was holding his right side and had a leather belt tightly bound over his upper abdomen. He was unable to take deep breaths, but there were decreased breath sounds over the right lateral and posterior lung fields. Once the belt was removed, there was no apparent swelling, but a depression was palpated at the lateral aspect between the eighth ninth rib interspace. The patient reported that he could replicate the bulge beneath the skin if he coughed. A chest x-ray showed an indistinct right basilar density with a potential small effusion possibly related to atelectasis or pneumonia (Figures 1A and 1B). There were no evident rib fractures. While preparing for a chest CT, the patient coughed, and the bulge recurred. CT images showed a large herniation of the right lower lobe between the 9th and 10th rib interspace. The adjacent ribs were separated with interruption of the associated intercostal muscles (Figures 2A and 2B, Figure 3 and Figure 4). The patient subsequently underwent a right thoracotomy with placement of a Gore-Tex patch to close the defect. A sterile seroma cavity had formed in the chest wall and was excised. The patient has recovered well and has not experienced further pain or recurrence of herniation on follow-up CT (Figure 5). Pulmonary herniation is a rare condition characterized by protrusion
我们提出了一个明显的肺疝的情况下,这是一个相对较低的锐锐度损伤持续,而移动一小负荷的砖。患者的症状是疼痛和呼吸困难,胸部图像显示右下叶通过肋间肌缺损有很大的突出。肺疝是罕见的,但通常与重大创伤或手术有关。这种程度的损伤发生在轻微的刺激下,但引起了显著的发病率。*通讯:Carvalho AM, Queen 's University Belfast School of Medicine, UK, E-mail: Paula.Carvalho@med.va.gov收稿日期:2018年6月15日;病例报告一名62岁男性因右下肋缘肿胀和疼痛而被送往急诊室。据报道,在2天前搬砖时出现了尖锐的撕裂性疼痛。几小时后,患者(吸烟者)咳嗽,疼痛加重,随后在该部位出现柔软的海绵状隆起。随着随后的咳嗽,肿胀增大,并变得严重疼痛,妨碍了正常的潮汐呼吸。病人用一条宽腰带进行外压,减轻了肿胀,以便继续工作。尽管压迫有帮助,但由于顽固性疼痛,他无法继续工作。经体格检查,病人神志清醒,没有立即出现痛苦。他有30包年的吸烟史,但健康状况良好,没有使用任何药物。生命体征正常,呼吸频率为22/分钟,呼吸浅。病人捂着自己的右侧身体,一条皮带紧紧地绑在他的上腹部。他不能深呼吸,但右外侧和后肺野呼吸音减弱。一旦皮带被移除,没有明显的肿胀,但在第八,第九肋骨间隙之间的侧面触诊到一个凹陷。病人报告说,如果他咳嗽,他可以复制皮肤下的隆起。胸部x线显示右侧基底动脉密度不明显,有可能与肺不张或肺炎有关的少量积液(图1A和1B)。没有明显的肋骨骨折。在准备胸部CT时,患者咳嗽,肿块复发。CT图像显示右下叶在第9和第10肋间隙间有一大块突出。相邻肋骨被分开,相关肋间肌被打断(图2A和2B,图3和图4)。患者随后行右开胸术,放置Gore-Tex补片以闭合缺损。胸壁形成无菌浆液腔并切除。患者恢复良好,随访CT未见进一步疼痛或疝复发(图5)。肺疝是一种罕见的疾病,其特征是肺突出至胸腔外。目前报告的病例不到300例。肺疝一般由图1A增高引起。入院胸部x线,PA片显示右基底动脉密度模糊增加,认为可能与肺不张或肺炎有关的潜在小积液。Carvalho AM(2018)重型肺疝合并轻微创伤1例放射诊断与影像杂志,2018 doi: 10.15761/RDI.1000140图2 a。胸部CT,无对比,纵隔窗。轴位片显示右下肺叶在第8和第9肋间隙间有很大的突出和胸壁缺损。后外侧肋间肌在大范围内不连续(图2B)。胸部CT,无对比,肺窗,轴位位与图2A相似。Carvalho AM(2018)重型肺疝合并轻微创伤1例放射诊断与影像杂志,2018 doi: 10.15761/RDI.1000140版权所有:©2018 Carvalho AM。这是一篇根据知识共享署名许可协议发布的开放获取文章,该协议允许在任何媒体上不受限制地使用、分发和复制,前提是要注明原作者和来源。图4。虚拟现实图像显示支气管和血管解剖与挤压通过胸壁缺陷图5。胸部CT,轴位图,胸壁缺损手术修复后获得胸壁缺损胸内压力,通常在创伤或胸外科手术后诊断[1]。自发性肺疝是罕见的,据报道,在咳嗽、打喷嚏、吹奏管乐器或举重可能造成肋骨或软骨损伤后发生[2-4]。这些事件在男性中最为常见,尤其是那些吸烟或肥胖的人,比如这个病例中的病人。并非所有的缺陷都需要手术修复。 手术适应症包括肺组织体积增大、疼痛和潜在的嵌顿。该患者可能在举重时肌肉纤维破裂,咳嗽引起的肺组织大面积疝出。引用1。石田,王晓明,王晓明(2018)术后肺肋间疝。呼吸素病例报告6:e00323。(Crossref) 2。O’shea M, Cleasby M(2012)临床医学图像。咳嗽所致肋间肌破裂后肺疝。中华医学杂志366:74。(Crossref) 3。Sulaiman A, Cottin V, De Souza Neto EP, Orsini A, Cordier JF等。(2006)咳嗽致肋间肺疝需手术治疗1例。今日外科36:978-980。(Crossref) 4。张建军,张建军,张建军,等(2000)原发性肺疝的临床观察。eurradiol 10:50 -502。(Crossref)
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引用次数: 0
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Diagnostic imaging
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