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Survival and Enhancing Fraction (enf) in Glioblastoma Multiforme (GBM) 多形性胶质母细胞瘤(GBM)的存活率和增强分数(enf)
Pub Date : 2017-01-01 DOI: 10.15761/rdi.1000118
S. Mills, G. Thompson, G. Buonaccorsi, Parker Gjm, A. Jackson
In GBM, enhancing fraction derived from the initial area under the contrast agent concentration curve ( IAUC ), EnF IAUC 60 , correlates with the MRI parameter K trans (contrast agent transfer coefficient). Thresholding voxels as enhancing when IAUC 60>2.5mMol.s (EnF IAUC 60>2.5 ) separates high from low grade glioma. The objectives were to evaluate the feasibility of deriving a signal intensity based enhancing fraction (EnF SI ), assess its relationship with EnF IAUC 60 measures and examine relationships with survival in GBM. 30 GBM had pre-operative pre and post-contrast T 1 -weighted imaging and a T 1 -DCE-MRI protocol. EnF IAUC 60>0 and EnF IAUC 60>2.5 were generated from IAUC 60 maps. EnF SI was derived from pre and post-contrast T1-weighted sequences. Bland/Altman plots assessed agreement between EnF measures. A multivariate Cox regression analysis examined the prognostic value of EnF measures. The mean difference between EnF IAUC 60>0 and EnF SI was 0.0378 (range -0.112-0.264, std. dev 0.07573) and between EnF IAUC 60>2.5 and EnF SI was -0.2492 (range -0.6096-0.2416, std. dev 0.2154). EnF SI demonstrated good correlation with both EnF IAUC 60>0 and EnF IAUC 60>2.5 but was not directly interchangeable with either metric. Increased EnF IAUC 60>0 was associated with prolonged survival (p=0.008). A non-significant trend was seen with EnF SI (p=0.061). EnF SI can be derived from conventional imaging and correlates with IAUC 60 based metrics. Furthermore, enhancing fraction conveys potential prognostic information in GBM.
在GBM中,造影剂浓度曲线下初始面积的增强分数(IAUC) EnF IAUC 60与MRI参数K trans(造影剂传递系数)相关。当IAUC 60>2.5mMol时,阈值体素增强。5 (EnF IAUC 60>2.5)区分高级别和低级别胶质瘤。目的是评估得出基于信号强度的增强分数(EnF SI)的可行性,评估其与EnF IAUC 60指标的关系,并检查与GBM患者生存的关系。30例GBM术前和造影后进行t1加权成像,并进行t1 -DCE-MRI检查。根据IAUC 60图谱生成EnF IAUC 60>0和EnF IAUC 60>2.5。EnF SI由对比前和对比后的t1加权序列得出。Bland/Altman图评估EnF措施之间的一致性。多变量Cox回归分析检验EnF测量的预后价值。EnF IAUC 60>0与EnF SI的平均差异为0.0378(范围为-0.112-0.264,std. dev为0.07573),EnF IAUC 60>2.5与EnF SI的平均差异为-0.2492(范围为-0.6096-0.2416,std. dev为0.2154)。EnF SI与EnF IAUC 60>0和EnF IAUC 60>2.5均表现出良好的相关性,但与任何一个指标都不能直接互换。EnF IAUC升高60>0与延长生存期相关(p=0.008)。EnF SI无显著性趋势(p=0.061)。EnF SI可以从常规成像中得出,并与基于IAUC 60的指标相关。此外,增强分数传达了GBM的潜在预后信息。
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引用次数: 0
MR imaging of uncommon complications of transforaminal 经椎间孔少见并发症的磁共振成像分析
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000113
Tan Ap, Quek St
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引用次数: 0
Functional magnetic resonance imaging: fuzzy inference analysis 功能磁共振成像:模糊推理分析
Pub Date : 2017-01-01 DOI: 10.15761/rdi.1000111
Bouharati Imane, Bouharati Khaoula, Bouharati Saddek, H. Mokhtar
Aim: Nowadays, functional MRI is widely used in the study of brain functions. If it has the advantage of being non-invasive and allows delimiting the zones that are activated at each stimulus in 3D, it presents several deficiencies. On the psychotic studies, the zones which activate induce the analyst in error in view of the complexity and the differences between individuals and their states of anxiety. Even minimal movements of the head influence the result; the response of the vascular system signal is delayed after the stimulus...etc. A heavy numerical processing in particular in statistical analyzes is necessary to refine the images. Despite this, difficulties persist. Method: In this study, a fuzzy logic system in this analysis is proposed. Viewing the complexity of the system, the variables that define the constructed image are considered as inaccurate variables and therefore fuzzy variable. The motor and emotional stimulus, the parasites movements, the anxiety state are considerate as inputs system. The quality of image constructed is the output system. The data base constructed permits adjusting input variables for optimal image. Conclusion: The proposed system allows defining the optimal interaction of the different factors for an optimal image. Considering the variables of input and output as fuzzy variables thus imprecise, this makes it possible to overcome the deficiencies of the system Correspondence to: Bouharati Saddek, Laboratory of intelligent systems UFAS Setif1 University, Setif, Algeira; Tel: +213771816302; E-mail: sbouharati@univ-setif.dz
目的:目前,功能磁共振成像在脑功能研究中得到了广泛的应用。如果它具有非侵入性的优点,并且可以在3D中划分每次刺激激活的区域,那么它也存在一些不足。在精神病研究中,由于个体及其焦虑状态之间的复杂性和差异,激活的区域导致了分析师的错误。即使是最小的头部运动也会影响结果;刺激后血管系统信号的反应延迟…大量的数值处理,特别是在统计分析中,是细化图像所必需的。尽管如此,困难依然存在。方法:在本研究中,提出了一个模糊逻辑分析系统。考虑到系统的复杂性,定义构造图像的变量被认为是不准确的变量,因此是模糊变量。运动和情绪刺激、寄生虫运动、焦虑状态被视为输入系统。图像构建的质量是输出系统。构建的数据库允许调整输入变量以获得最优图像。结论:所提出的系统可以定义不同因素的最佳交互作用,以获得最佳图像。考虑到输入和输出的变量是模糊变量,因此不精确,这使得有可能克服系统的缺陷通信:Bouharati Saddek,智能系统实验室UFAS Setif1大学,Setif,阿尔及利亚;电话:+ 213771816302;电子邮件:sbouharati@univ-setif.dz
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引用次数: 2
Quantitative and qualitative evaluation of the Wide Volume (WV) versus Helical acquisition on a 320-detector row computed tomography for the exploration of the abdominopelvic region in adults 定量和定性评价宽体积(WV)和螺旋采集在320个检测器行计算机断层扫描上用于成人腹部骨盆区域的探测
Pub Date : 2017-01-01 DOI: 10.15761/rdi.1000116
C. Roy, R. Quin, A. Labani, P. Leyendecker, L. Mertz, M. Ohana
Purpose: To evaluate the best protocol to be used in WV mode for the abdominopelvic region in terms of radiation dose and image quality by comparison with the helical mode. Methods and materials: This study was performed on a 320 x 0.5 mm detector row CT unit. By using several simulations on topograms data and phantoms analysis, we registered CTDIvol. Then, a clinical study on CTUrography was performed, each patient being its own standard. Results: The collimation of 10 cm (200 x 0.5 mm) with 5 volumes had the lowest CTDIvol. This can be explained by several physical phenomena. In the clinical study, the average radiation dose reduction was found to be at 44.03% ± 0.36% (p<0.001). Concerning the qualitative evaluation of the stitching of different volumes and the overall image quality, it was found excellent. Conclusion: Wide Volume CT scanning using 5 volumes of 10cm (200x0.5mm) significantly reduces the radiation dose with an excellent image quality. Correspondence to: Catherine Roy, Department of Radiology, University Hospital of Strasbourg – New Civil Hospital, Strasbourg Cedex, France; Tel: +333369550731; Fax: +3333691815; E-mail: catherine.roy@chru-strasbourg.fr
目的:通过与螺旋模式的比较,从辐射剂量和图像质量方面评价WV模式在腹骨盆区域的最佳方案。方法和材料:本研究在320 x 0.5 mm检测器行CT装置上进行。通过对地形图数据的多次模拟和幻影分析,我们注册了CTDIvol。然后进行ct临床研究,每个患者都有自己的标准。结果:5片10 cm (200 × 0.5 mm)的准直层CTDIvol最低。这可以用几种物理现象来解释。在临床研究中,平均辐射剂量降低率为44.03%±0.36% (p<0.001)。在对不同体积的拼接和整体图像质量进行定性评价时,认为该方法是优秀的。结论:5个10cm (200x0.5mm)的宽体积CT扫描可显著降低辐射剂量,图像质量良好。通信对象:Catherine Roy,斯特拉斯堡大学医院放射科-法国斯特拉斯堡新民用医院;电话:+ 333369550731;传真:+ 3333691815;电子邮件:catherine.roy@chru-strasbourg.fr
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引用次数: 2
Unilateral condylar hyperplasia recurrence after orthognathic surgery: a case report 正颌手术后单侧髁突增生复发1例
Pub Date : 2017-01-01 DOI: 10.15761/rdi.1000108
G. Follacchio, Maria Ricci, Ramieri, Vellone, Viviana Frantellizzi, M. Liberatore, F. Monteleone, Liana Civitelli, P. Cascone, G. Vincentis
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引用次数: 0
Pneumomediastinum in a smoking free-base cocaine abuser during sexual intercourse 纵隔气肿吸烟游离基可卡因滥用者性交时
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000110
G. Gioia
Clinical history: There were no pathologies in family history. He did not take any medications. He was smoking 10 cigarettes daily. He was a habitual cocaine user. The patient had a blood pressure of 120/80 mmHg, a resting heart rate of 73 beats/minute, a respiratory rate of 16 breaths/minute, an oxygen saturation of 98%, and no temperature. The main symptom was an initial sharp retrosternal chest pain starting 5 hours before in the course of free-base cocaine smoking. Dyspnea and retrosternal pain were increasing with breath and chest movements. The pain was intensifying 2 hours earlier during sexual intercourse with a female partner. Then, the retrosternal pain was constant as regards intensity and localization. Subcutaneous emphysema of the neck was palpable on physical examination. Inspiratory effort and elicited rib pain was evident on chest examination. Cardiopulmonary auscultation and electrocardiography were normal.
临床病史:家族史无病理。他没有服用任何药物。他每天抽10支烟。他有吸食可卡因的习惯。患者血压120/80 mmHg,静息心率73次/分钟,呼吸频率16次/分钟,血氧饱和度98%,无体温。主要症状为游离可卡因吸食前5小时开始的胸骨后剧烈胸痛。呼吸困难和胸骨后疼痛随着呼吸和胸部运动而增加。2小时前与女性伴侣性交时疼痛加重。然后,胸骨后疼痛的强度和定位是恒定的。体格检查时可触及颈部皮下肺气肿。胸部检查显示吸气用力和引起的肋骨疼痛。心肺听诊、心电图正常。
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引用次数: 1
A case of the appendix myxomas 阑尾黏液瘤1例
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000102
O. Tanaka, M. Hattori, Kentarou Nonaka, Yuko Yamada, Akihiro Tsuzaki, Tomomi Kunieda, E. Yama
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引用次数: 0
Foxels for high flux, high resolution computed tomography (foxelct) Using broad x-ray focal spots Foxels用于高通量,高分辨率计算机断层扫描(foxelct),使用宽x射线焦点
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000103
Graham Alvare, R. Gordon
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引用次数: 3
Radiography and transmission measurements on gold and silver from the moche tomb “Señora de Cao” 莫切墓“Señora de Cao”金银的射线照相及透射测量
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000106
R. Cesareo, A. Bustamante, S. Azeredo, R. Lopes, R. Jordan, Arabel Fernández, E. GiovanniEGigante
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引用次数: 10
Vocal fold paralysis following fine needle aspiration of the thyroid gland complicated by a neck hematoma 甲状腺细针穿刺后声带麻痹并发颈部血肿
Pub Date : 2017-01-01 DOI: 10.15761/RDI.1000109
Z. ZidanMahmood, A. Brenner, N. Carmel, Y. Oestreicher‐Kedem
Objective: To describe the mechanism and clinical course of vocal fold paralysis (VFP) following fine needle aspiration (FNA) of the thyroid gland. Case report: An 80-year old female presented to the emergency room due to hoarseness, dyspnea, and neck swelling. Her history was significant for FNA of the thyroid gland eight days earlier. Physical examination revealed left VFP and a left neck mass. Computed tomography of the neck was suggestive of a left neck hematoma. She was treated conservatively and her pain and neck swelling subsided gradually. Good left vocal movement was observed four months later. Conclusion: VFP is a rare complication of FNA of the thyroid gland. Physicians performing this procedure should be aware of this complication. We suggest that this sequela be discussed with the patient prior to the procedure and be included in the informed patient consent form. Correspondence to: Yael Oestreicher-Kedem, Department of Otolaryngology, Head & Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center 6 Weizman St. Tel-Aviv, Israel, Tel: +972-52-6212179; Fax: +972-36052905; E-mail: dkyo@013.net
目的:探讨甲状腺细针穿刺后声带麻痹(VFP)的发病机制和临床过程。病例报告:一名80岁女性因声音嘶哑、呼吸困难和颈部肿胀而被送往急诊室。她的甲状腺FNA病史在8天前有重要意义。体格检查显示左侧VFP和左侧颈部肿块。颈部电脑断层显示左颈部有血肿。经保守治疗,疼痛及颈部肿胀逐渐消退。四个月后观察到良好的左声带运动。结论:VFP是一种罕见的甲状腺FNA并发症。实施这种手术的医生应该意识到这种并发症。我们建议在手术前与患者讨论这种后遗症,并将其包括在知情患者同意书中。通讯:Yael Oestreicher-Kedem,特拉维夫Sourasky医疗中心6 Weizman St. Tel- aviv耳鼻喉科,头颈外科和颌面外科,Tel: +972-52-6212179;传真:+ 972 - 36052905;电子邮件:dkyo@013.net
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Diagnostic imaging
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