The occurrence of a case in which purulent pericarditis occurred in conjunction with a peritoneal abscess indicates that an additional etiologic factor in purulent pericarditis may be communication between the pericardial and peritoneal cavities through a congenitally weakened portion of the diaphragm.
Thirty-three subjects with bronchial asthma and 15 subjects with asthmatic bronchitis caused by occupational exposure to simple chemicals were submitted to an allergologic investigation. Essentially this consisted of skin tests, inhalation tests, determination of some types of circulating antibodies, carried out with nonirritant concentrations of simple chemicals and with usual allergens. Results indicated that bronchial asthma and asthmatic bronchitis, due to micromolecular substances, may be either irritative (28 cases) or allergic (15 cases). In five subjects the mechanism could not be established. A certain substance may give rise, in different subjects, to both types of bronchial asthma and asthmatic bronchitis mentioned above. Besides the well-known picture of bronchial asthma with reagins, the authors describe another pattern of skin and bronchial response; this pattern has many features in common with the delayed hypersensitivity.
Primary smooth muscle tumors of the lung are rare, and usually arise from the uterus, gastrointestinal tract, or soft tissue. The patient reported was found at autopsy to have leiomyosarcoma which arose in the left mainstem bronchus and metastasized to the right lung, liver, pancreas, both kidneys, and brain, sparing the lymphatic system. This tumor is slow growing and late metastasizing, in spite of its degree of anaplasia, and has a better prognosis for surgical cure than does bronchogenic carcinoma.
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