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Minimally invasive management of a post-cholecystectomy bile leak using a microvascular plug. 微血管塞微创治疗胆囊切除术后胆漏。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-19 DOI: 10.4274/dir.2025.253601
Mohammed Misbahuddin-Leis, Andreas R R Weiß, Yazan Amin, Robert Grützmann, Axel Schmid

Bouveret syndrome is a rare form of gallstone ileus in which a gallstone causes gastric outlet obstruction via a cholecystoenteric fistula. We present the case of an elderly patient who underwent emergency surgery due to clinical signs of gastric outlet obstruction. Intraoperatively, a large gallstone was identified and removed from the duodenum. A subtotal cholecystectomy was performed, during which the identification of the course of the cystic duct was limited due to considerable inflammatory changes. In the early postoperative period, bile-stained output from the surgical drain raised suspicion of a leak from the cystic duct stump. Given the patient's clinical status and the complexity of the local anatomy with severely inflamed and fibrotic tissues in the hepatoduodenal ligament, the decision was made to proceed with percutaneous treatment. A percutaneous transhepatic biliary drainage was established, and contrast extravasation from the cystic duct remnant was confirmed via fluoroscopic cholangiography. Through the same access, a microvascular plug was successfully deployed into the cystic duct, achieving immediate cessation of bile leakage. The patient's clinical condition improved markedly, and no further intervention was required. This case demonstrates the successful off-label use of polytetrafluoroethylene-covered vascular occlusion devices in managing biliary complications.

布韦莱特综合征是一种罕见的胆结石性肠梗阻,其中胆结石通过胆囊肠瘘引起胃出口阻塞。我们报告一位因胃出口梗阻的临床症状而接受紧急手术的老年患者。术中发现一大块胆结石,并从十二指肠取出。进行了胆囊次全切除术,在此期间,由于相当大的炎症变化,胆囊管的过程受到限制。术后早期,从手术引流管流出的胆汁染色引起了对胆囊管残端泄漏的怀疑。考虑到患者的临床情况和局部解剖的复杂性以及肝十二指肠韧带严重炎症和纤维化组织,我们决定进行经皮治疗。建立经皮经肝胆道引流,并通过透视胆道造影证实结缔组织残余囊管的造影剂外渗。通过同样的通道,一个微血管塞成功地部署到胆囊管中,立即停止了胆汁泄漏。患者临床状况明显改善,无需进一步干预。本病例展示了聚四氟乙烯覆盖血管闭塞装置在治疗胆道并发症中的成功应用。
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引用次数: 0
Pleural tail sign in computed tomography-guided lung biopsy: an imaging predictor of severe pneumothorax requiring chest tube placement. ct引导下肺活检胸膜尾征:需要置胸管的严重气胸的影像学预测指标。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-19 DOI: 10.4274/dir.2025.253503
Jacob Jalil Hassan, Jakob Leonhardi, Timm Denecke, Anne Beeskow, Manuel Florian Struck, Anne-Kathrin Höhn, Sebastian Krämer, Armin Frille, Hans-Jonas Meyer

Purpose: Pneumothorax is the most common complication following computed tomography (CT)-guided percutaneous transthoracic needle biopsy. In severe cases, it may require chest tube placement, which is associated with increased morbidity. The aim of this study was to evaluate the prognostic value of the pleural tail sign (PTS) as an imaging marker for predicting pneumothorax incidence and severity after lung biopsy.

Methods: A total of 477 patients (mean age 65 ± 11.7 years, 37.2% women) undergoing CT-guided lung biopsies between 2012 and 2021 were retrospectively analyzed in this study. The presence and morphological subtype of PTS-classified as thin PTS or triangular PTS-were assessed on pre-interventional CT imaging. Associations between PTS and pneumothorax outcomes were evaluated using univariate and multivariate binary logistic regression analyses.

Results: No statistically significant association was found between the overall presence of PTS and the incidence of pneumothorax (P = 0.052). However, patients with a triangular PTS showed a significantly increased risk of severe pneumothorax requiring chest tube placement (odds ratio: 2.092, 95% confidence interval: 1.097-3.990, P = 0.025), whereas a thin PTS did not show a statistically significant effect (P = 0.456).

Conclusion: Although PTS does not reliably predict overall pneumothorax risk after CT‑guided lung biopsy, its triangular subtype may serve as a prognostic imaging marker for identifying patients at increased risk of severe pneumothorax requiring chest tube placement.

Clinical significance: The identification of a triangular PTS on pre-interventional CT imaging may help to stratify patients at higher risk of severe pneumothorax following CT-guided lung biopsy. This could enable more informed procedural planning, potentially leading to improved patient outcomes.

目的:气胸是CT引导下经皮穿刺活检后最常见的并发症。在严重的情况下,可能需要放置胸管,这与发病率增加有关。本研究的目的是评估胸膜尾征(PTS)作为肺活检后预测气胸发生率和严重程度的影像学标志物的预后价值。方法:回顾性分析2012年至2021年间接受ct引导下肺活检的477例患者(平均年龄65±11.7岁,37.2%为女性)。通过介入前CT成像评估PTS的存在和形态亚型,分为薄PTS和三角形PTS。采用单因素和多因素二元logistic回归分析评估PTS与气胸预后之间的关系。结果:PTS总体存在与气胸发生率无统计学意义(P = 0.052)。然而,三角形PTS患者发生严重气胸需要置管的风险显著增加(优势比:2.092,95%可信区间:1.097-3.990,P = 0.025),而薄PTS无统计学意义(P = 0.456)。结论:尽管PTS不能可靠地预测CT引导下肺活检后的整体气胸风险,但其三角形亚型可作为预后成像标记,用于识别需要置胸管的严重气胸风险增加的患者。临床意义:在介入前CT成像上识别三角形PTS可能有助于对CT引导下肺活检后发生严重气胸高风险患者进行分层。这可以使更知情的程序规划,潜在地导致改善患者的结果。
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引用次数: 0
Analysis of the baseline multiphase computed tomographic angiography findings to predict clinical outcomes in patients with middle cerebral artery M1 occlusion treated with mechanical thrombectomy. 分析脑中动脉M1闭塞机械取栓治疗患者的基线多期计算机断层血管造影结果预测临床结果。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-19 DOI: 10.4274/dir.2025.253549
Esra Çıvgın, Hasan Bayındır

Purpose: We aimed to evaluate the predictive ability of baseline multiphase computed tomographic angiography (mCTA) findings and the time from symptom onset to imaging in predicting functional outcomes in patients with middle cerebral artery (MCA) M1 occlusion treated with mechanical thrombectomy (MT).

Methods: A total of 70 patients were evaluated retrospectively. The time between the onset of symptoms and imaging, thrombus density, estimated thrombus length, the Alberta Stroke Program Early CT Score (ASPECTS) on non-contrast CT, collateral circulation (CC), actual thrombus length, and clot burden score were assessed on mCTA images. Patients with a 90-day modified Rankin scale score of 0-2 were categorized as having good outcomes, whereas the others were categorized as having poor outcomes. The mCTA findings of patients with good and poor outcomes were compared, and binary logistic regression analysis was performed to identify independent predictors that could affect clinical outcomes.

Results: The estimated thrombus length, the ASPECTS, thrombus density, clot burden score, and CC grade were not significantly different between patients with good and poor outcomes. The actual thrombus length was shorter in patients with good outcomes than in those with poor outcomes (15.9 mm versus 21.5 mm, P = 0.001). Binary logistic regression analysis revealed that actual thrombus length [P = 0.005, odds ratio (OR): 0.754, 95% confidence interval (CI): 0.61-0.92] and thrombus density (P = 0.022, OR: 1.167, 95% CI: 1.02-1.33) were independent variables for a good outcome. The optimal cut-off value for actual thrombus length was 18.7 mm (area under the curve, 0.74; 95% CI: 0.62-0.86; P = 0.001) to predict good outcomes.

Conclusion: Higher thrombus density and actual thrombus length shorter than 18.7 mm were associated with good clinical outcomes. However, no significant correlation was found between clinical outcomes and the ASPECTS, CC degree, or clot burden scores.

Clinical significance: Thrombus length and density are associated with the clinical outcome of patients with MCA M1 occlusion treated with MT who have distal collateral filling sufficient to depict thrombus margins in mCTA.

目的:我们旨在评估基线多期计算机断层血管造影(mCTA)结果的预测能力,以及从症状发作到成像的时间预测机械取栓(MT)治疗的大脑中动脉(MCA) M1闭塞患者的功能结局。方法:对70例患者进行回顾性分析。在mCTA图像上评估症状出现和成像之间的时间、血栓密度、估计血栓长度、非对比CT上的阿尔伯塔卒中计划早期CT评分(ASPECTS)、侧支循环(CC)、实际血栓长度和血栓负荷评分。90天改良Rankin量表评分为0-2分的患者被归类为预后良好,而其他患者被归类为预后不良。比较预后良好和预后较差患者的mCTA结果,并进行二元logistic回归分析,以确定可能影响临床预后的独立预测因素。结果:预后好的和预后差的患者的预估血栓长度、ASPECTS、血栓密度、血块负荷评分和CC分级无显著差异。结果良好的患者血栓的实际长度比结果较差的患者短(15.9 mm比21.5 mm, P = 0.001)。二元logistic回归分析显示,实际血栓长度[P = 0.005,优势比(OR): 0.754, 95%可信区间(CI): 0.61-0.92]和血栓密度(P = 0.022, OR: 1.167, 95% CI: 1.02-1.33)是预后良好的独立变量。实际血栓长度的最佳截断值为18.7 mm(曲线下面积0.74;95% CI: 0.62-0.86; P = 0.001),预测良好的预后。结论:较高的血栓密度和小于18.7 mm的实际血栓长度与较好的临床效果相关。然而,临床结果与ASPECTS、CC程度或凝块负担评分之间未发现显著相关性。临床意义:血栓的长度和密度与接受MT治疗的MCA M1闭塞患者的临床结果相关,这些患者的远端侧支充盈足以在mCTA上描绘血栓边缘。
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引用次数: 0
Hepatic alveolar echinococcosis: a great tumor mimicker. 肝肺泡包虫病:一个伟大的肿瘤模仿者。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-17 DOI: 10.4274/dir.2025.253582
Diğdem Kuru Öz, Ayşe Erden
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引用次数: 0
Computed tomography and magnetic resonance imaging findings in congenital cardiovascular anomalies. 先天性心血管异常的计算机断层和磁共振成像表现。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-17 DOI: 10.4274/dir.2025.252878
Mustafa Koplay, Nusret Seher

The incidence of congenital heart disease (CHD) is approximately 6-7 per 1,000 newborns. With advanced diagnostic, medical, and surgical methods, survival of CHD is increasing, as is the number of people living with CHD. Echocardiography is a useful modality in non-invasive imaging, whereas magnetic resonance imaging (MRI), cardiac MR (CMR), cardiac computed tomography (CT), and CT angiography (CTA) are increasingly gaining ground in congenital cardiac imaging with developing technology. Considering the limited postoperative use of echocardiography, these techniques have assumed vital roles with the increasing population of CHD in children and adults. CMR and cardiac CT can complement the information obtained with echocardiography and invasive cardiac catheterization and can sometimes provide more detail. In postoperative imaging of CHD, CMR allows an evaluation of anatomy, especially with spin echo MRI techniques, whereas cine MRI, created in gradient echo sequences, allows functional data to be obtained. Phase contrast CMR data provides information on flow direction and flow rate, allowing accurate measurement of regurgitation and shunt volume. In addition, in post-gadolinium imaging, data such as on MR angiography, myocardial perfusion, and fibrosis can be obtained with CMR. Cardiac CT and CTA provide great advantages, especially in newborns, by almost completely reducing movement and respiratory artifacts through capabilities such as high spatial and temporal resolution, fast acquisition, and short acquisition time. Three-dimensional reformatted images with contrast-enhanced CMR or cardiac CT/CTA provide excellent visualization of vascular structures in complex CHDs. Coronary imaging can be viewed more easily with CT imaging. This article reviews the literature to provide an overview of the diagnostic value, relative advantages, and overall evaluation of CMR and cardiac CT examinations in the diagnosis and postoperative follow-up of CHD.

先天性心脏病(CHD)的发病率约为每1000名新生儿6-7例。随着先进的诊断、医疗和手术方法的发展,冠心病患者的存活率越来越高,冠心病患者的数量也越来越多。超声心动图是一种有用的无创成像方式,而磁共振成像(MRI)、心脏磁共振成像(CMR)、心脏计算机断层扫描(CT)和CT血管成像(CTA)随着技术的发展,在先天性心脏成像中越来越受欢迎。考虑到术后超声心动图的使用有限,这些技术在儿童和成人冠心病患者的增加中发挥了至关重要的作用。CMR和心脏CT可以补充超声心动图和有创心导管术获得的信息,有时可以提供更多的细节。在冠心病的术后成像中,CMR允许对解剖结构进行评估,特别是使用自旋回波MRI技术,而在梯度回波序列中创建的电影MRI允许获得功能数据。相衬CMR数据提供流向和流量信息,允许精确测量回流和分流体积。此外,在钆后成像中,CMR可以获得MR血管造影、心肌灌注和纤维化等数据。心脏CT和CTA通过高空间和时间分辨率、快速采集和短采集时间等能力,几乎完全减少了运动和呼吸伪影,提供了巨大的优势,特别是在新生儿中。对比增强CMR或心脏CT/CTA的三维重构图像可以很好地显示复杂冠心病的血管结构。冠状动脉成像可以更容易地观察到CT成像。本文通过文献综述,综述CMR与心脏CT检查在冠心病诊断及术后随访中的诊断价值、相对优势及综合评价。
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引用次数: 0
Pix2Pix generative-adversarial network in improving the quality of T2-weighted prostate magnetic resonance imaging: a multi-reader study. Pix2Pix生成对抗网络在提高t2加权前列腺磁共振成像质量中的应用:一项多读卡器研究。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-06 Epub Date: 2025-05-05 DOI: 10.4274/dir.2025.243102
Yeliz Başar, Mustafa Said Kartal, Mustafa Ege Seker, Deniz Alis, Delal Seker, Müjgan Orman, Sabri Şirolu, Serpil Kurtcan, Aydan Arslan, Nurper Denizoğlu, İlkay Öksüz, Ercan Karaarslan

Purpose: To assess the performance and feasibility of generative deep learning in enhancing the image quality of T2-weighted (T2W) prostate magnetic resonance imaging (MRI).

Methods: Axial T2W images from the prostate imaging: cancer artificial intelligence dataset (n = 1,476, biologically males; n = 1,500 scans) were used, partitioned into training (n = 1300), validation (n = 100), and testing (n = 100) sets. A Pix2Pix model was trained on original and synthetically degraded images, generated using operations such as motion, Gaussian noise, blur, ghosting, spikes, and bias field inhomogeneities to enhance image quality. The efficacy of the model was evaluated by seven radiologists using the prostate imaging quality criteria to assess original, degraded, and improved images. The evaluation also included tests to determine whether the images were original or synthetically improved. Additionally, the model's performance was tested on the in-house external testing dataset of 33 patients. The statistical significance was assessed using the Wilcoxon signedrank test.

Results: Results showed that synthetically improved images [median score (interquartile range) 4.71 (1)] were of higher quality than degraded images [3.36 (3), P = 0.0001], with no significant difference from original images [5 (1.14), P > 0.05]. Observers equally identified original and synthetically improved images as original (52% and 53%), proving the model's ability to retain realistic attributes. External testing on a dataset of 33 patients confirmed a significant improvement (P = 0.001) in image quality, from a median score of 4 (2.286)-4.71 (1.715).

Conclusion: The Pix2Pix model, trained on synthetically degraded data, effectively improved prostate MRI image quality while maintaining realism and demonstrating both applicability to real data and generalizability across various datasets.

Clinical significance: This study critically assesses the efficacy of the Pix2Pix generative-adversarial network in enhancing T2W prostate MRI quality, demonstrating its potential to produce high-quality, realistic images indistinguishable from originals, thereby potentially advancing radiology practice by improving diagnostic accuracy and image reliability.

目的:评估生成式深度学习在提高前列腺t2加权(T2W)磁共振成像(MRI)图像质量中的性能和可行性。方法:来自前列腺成像:癌症人工智能数据集的T2W轴向图像(n = 1476,生理男性;使用了N = 1500次扫描),分为训练集(N = 1300)、验证集(N = 100)和测试集(N = 100)。使用运动、高斯噪声、模糊、重影、尖峰和偏置场不均匀性等操作生成的原始图像和综合退化图像,对Pix2Pix模型进行了训练,以提高图像质量。该模型的疗效由7名放射科医生使用前列腺成像质量标准来评估原始,退化和改进的图像。评估还包括确定图像是原始的还是经过综合改进的测试。此外,在33例患者的内部外部测试数据集上对模型的性能进行了测试。采用Wilcoxon符号检验评估统计学显著性。结果:结果显示,综合改进图像[中位数得分(四分位间距)4.71(1)]的质量优于退化图像[3.36 (3),P = 0.0001],与原始图像[5 (1.14),P = 0.0001]无显著差异。观察者对原始图像和综合改进图像的识别程度相同(52%和53%),证明了模型保留真实属性的能力。对33名患者的数据集进行的外部测试证实了图像质量的显着改善(P = 0.001),中位评分为4(2.286)-4.71(1.715)。结论:在综合退化数据上训练的Pix2Pix模型,在保持真实感的同时,有效地提高了前列腺MRI图像质量,并展示了对真实数据的适用性和跨各种数据集的通用性。临床意义:本研究批判性地评估了Pix2Pix生成-对抗网络在提高T2W前列腺MRI质量方面的功效,证明了其产生高质量、真实图像的潜力,与原始图像没有区别,从而通过提高诊断准确性和图像可靠性,潜在地推进放射学实践。
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引用次数: 0
Detection of synovial inflammation in the sacroiliac joint space through intravoxel incoherent motion imaging: an alternative to contrast agents. 通过体外非相干运动成像检测骶髂关节间隙的滑膜炎症:造影剂的替代品。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-06 Epub Date: 2024-08-19 DOI: 10.4274/dir.2024.242749
Murat Ağırlar, Barış Genç, Aysu Başak Özbalcı
<p><strong>Purpose: </strong>We investigated the diagnostic accuracy of simplified intravoxel incoherent motion (IVIM) imaging for detecting synovial inflammation in the sacroiliac joint (SIJ) in a population with active sacroiliitis.</p><p><strong>Methods: </strong>In accordance with the Assessment of Spondyloarthritis International Society criteria, 86 SIJs of 46 patients with active sacroiliitis were included in this retrospective study conducted between November 2020 and January 2022. Based on T1-weighted post-gadolinium images, the SIJs were divided into two groups: synovial inflammation positive (SIP) (n = 28) and synovial inflammation negative (SIN) (n = 58). Synovial areas in the SIJ space were independently and blindly reviewed for the presence of inflammation by two radiologists with differing levels of expertise in radiology. Using four b values, apparent diffusion coefficient (ADC)= ADC (0, 800) and the simplified 3T IVIM method parameters true diffusion coefficient (D<sub>1</sub>)= ADC (50, 800), D= ADC (400, 800), f<sub>1</sub>= f (0, 50, 800), f<sub>2</sub>= f (0, 400, 800), pseudodiffusion coefficient (D*)= D* (0, 50, 400, 800), ADC<sub>low</sub> = ADC (0, 50), and ADC<sub>diff</sub>= ADC<sub>low</sub> - D were generated voxel by voxel for each patient. The IVIM and ADC parameters at the SIN and SIP joints were compared.</p><p><strong>Results: </strong>The D parameter was significantly increased in SIP areas (1.23 ± 0.34 × 10<sup>-3</sup> mm<sup>2</sup>/s) compared with SIN areas (1.02 ± 0.16 × 10<sup>-3</sup> mm<sup>2</sup>/s) (<i>P</i> = 0.004). Conversely, the D* parameter was significantly decreased in SIP areas (21.78 ± 3.77 × 10<sup>-3</sup> mm<sup>2</sup>/s) compared with SIN areas (16.19 ± 4.58 × 10<sup>-3</sup> mm<sup>2</sup>/s) (<i>P</i> < 0.001). When the optimal cut-off value of 1.11 × 10<sup>-3</sup> mm<sup>2</sup>/s was selected, the sensitivity for the D value was 71% and the specificity was 72% [area under the curve (AUC): 0.716)]. When the optimal cut-off value of 21.06 × 10<sup>-3</sup> mm<sup>2</sup>/s was selected, the sensitivity for the D* value was 78.6%, and the specificity was 79.3% (AUC: 0.829). The interclass correlation coefficient was excellent for f<sub>1</sub>, f<sub>2</sub> D*, D, and ADC<sub>diff</sub>, good for ADC<sub>low</sub> and D<sub>1</sub>, but reasonable for ADC.</p><p><strong>Conclusion: </strong>The presence of synovial inflammation in the SIJ can be evaluated with high sensitivity and specificity using only four b values through the simplified IVIM method without the need for a contrast agent.</p><p><strong>Clinical significance: </strong>IVIM imaging is a technique that allows us to gain insights into tissue perfusion without the administration of contrast agents, utilizing diffusion-weighted images. In this study, for the first time, we demonstrated the potential of detecting synovial inflammation in the SIJ using IVIM, specifically through the pseudodiffusion (D*) parameter, without
目的:我们研究了简化体素内非相干运动(IVIM)成像在活动性骶髂关节炎人群中检测骶髂关节(SIJ)滑膜炎症的诊断准确性:根据脊柱关节炎国际协会的评估标准,这项于2020年11月至2022年1月进行的回顾性研究纳入了46名活动性骶髂关节炎患者的86个骶髂关节。根据 T1 加权钆后图像,SIJ 被分为两组:滑膜炎症阳性组(SIP)(28 人)和滑膜炎症阴性组(SIN)(58 人)。SIJ 间隙中的滑膜区域由两名放射学专业水平不同的放射科医生进行独立盲检,以确定是否存在炎症。使用四个 b 值,表观扩散系数(ADC)= ADC(0,800)和简化的 3T IVIM 方法参数真实扩散系数(D1)= ADC(50,800),D= ADC(400,800)、f1= f(0,50,800),f2= f(0,400,800),假扩散系数(D*)= D*(0,50,400,800),ADClow= ADC(0,50),ADCdiff= ADClow - D。对 SIN 和 SIP 关节处的 IVIM 和 ADC 参数进行比较:与 SIN 区域(1.02 ± 0.16 × 10-3 mm2/s)相比,SIP 区域的 D 参数(1.23 ± 0.34 × 10-3 mm2/s)明显增加(P = 0.004)。相反,与 SIN 区域(16.19 ± 4.58 × 10-3 mm2/s)相比,SIP 区域的 D* 参数(21.78 ± 3.77 × 10-3 mm2/s)明显降低(P < 0.001)。当选择最佳临界值 1.11 × 10-3 mm2/s 时,D 值的灵敏度为 71%,特异度为 72% [曲线下面积 (AUC): 0.716)]。当选择最佳截断值 21.06 × 10-3 mm2/s 时,D* 值的灵敏度为 78.6%,特异度为 79.3%(AUC:0.829)。f1、f2 D*、D和ADCdiff的类间相关系数极佳,ADClow和D1的类间相关系数良好,但ADC的类间相关系数尚可:结论:通过简化的 IVIM 方法,只需使用四个 b 值就能评估 SIJ 滑膜炎症的存在,具有很高的灵敏度和特异性,无需使用造影剂:IVIM成像是一种无需使用造影剂、利用弥散加权成像即可深入了解组织灌注情况的技术。在这项研究中,我们首次证明了利用 IVIM,特别是通过伪扩散(D*)参数,无需造影剂即可检测 SIJ 滑膜炎症的潜力。
{"title":"Detection of synovial inflammation in the sacroiliac joint space through intravoxel incoherent motion imaging: an alternative to contrast agents.","authors":"Murat Ağırlar, Barış Genç, Aysu Başak Özbalcı","doi":"10.4274/dir.2024.242749","DOIUrl":"10.4274/dir.2024.242749","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;We investigated the diagnostic accuracy of simplified intravoxel incoherent motion (IVIM) imaging for detecting synovial inflammation in the sacroiliac joint (SIJ) in a population with active sacroiliitis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In accordance with the Assessment of Spondyloarthritis International Society criteria, 86 SIJs of 46 patients with active sacroiliitis were included in this retrospective study conducted between November 2020 and January 2022. Based on T1-weighted post-gadolinium images, the SIJs were divided into two groups: synovial inflammation positive (SIP) (n = 28) and synovial inflammation negative (SIN) (n = 58). Synovial areas in the SIJ space were independently and blindly reviewed for the presence of inflammation by two radiologists with differing levels of expertise in radiology. Using four b values, apparent diffusion coefficient (ADC)= ADC (0, 800) and the simplified 3T IVIM method parameters true diffusion coefficient (D&lt;sub&gt;1&lt;/sub&gt;)= ADC (50, 800), D= ADC (400, 800), f&lt;sub&gt;1&lt;/sub&gt;= f (0, 50, 800), f&lt;sub&gt;2&lt;/sub&gt;= f (0, 400, 800), pseudodiffusion coefficient (D*)= D* (0, 50, 400, 800), ADC&lt;sub&gt;low&lt;/sub&gt; = ADC (0, 50), and ADC&lt;sub&gt;diff&lt;/sub&gt;= ADC&lt;sub&gt;low&lt;/sub&gt; - D were generated voxel by voxel for each patient. The IVIM and ADC parameters at the SIN and SIP joints were compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The D parameter was significantly increased in SIP areas (1.23 ± 0.34 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) compared with SIN areas (1.02 ± 0.16 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) (&lt;i&gt;P&lt;/i&gt; = 0.004). Conversely, the D* parameter was significantly decreased in SIP areas (21.78 ± 3.77 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) compared with SIN areas (16.19 ± 4.58 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) (&lt;i&gt;P&lt;/i&gt; &lt; 0.001). When the optimal cut-off value of 1.11 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s was selected, the sensitivity for the D value was 71% and the specificity was 72% [area under the curve (AUC): 0.716)]. When the optimal cut-off value of 21.06 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s was selected, the sensitivity for the D* value was 78.6%, and the specificity was 79.3% (AUC: 0.829). The interclass correlation coefficient was excellent for f&lt;sub&gt;1&lt;/sub&gt;, f&lt;sub&gt;2&lt;/sub&gt; D*, D, and ADC&lt;sub&gt;diff&lt;/sub&gt;, good for ADC&lt;sub&gt;low&lt;/sub&gt; and D&lt;sub&gt;1&lt;/sub&gt;, but reasonable for ADC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The presence of synovial inflammation in the SIJ can be evaluated with high sensitivity and specificity using only four b values through the simplified IVIM method without the need for a contrast agent.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;IVIM imaging is a technique that allows us to gain insights into tissue perfusion without the administration of contrast agents, utilizing diffusion-weighted images. In this study, for the first time, we demonstrated the potential of detecting synovial inflammation in the SIJ using IVIM, specifically through the pseudodiffusion (D*) parameter, without ","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"612-618"},"PeriodicalIF":1.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison of two artificial intelligence-based methods for assessing bone age in Turkish children: BoneXpert and VUNO Med-Bone Age. 比较两种基于人工智能的土耳其儿童骨龄评估方法:BoneXpert 和 VUNO Med-Bone Age。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-06 Epub Date: 2024-09-02 DOI: 10.4274/dir.2024.242790
Evrim Özmen, Hande Özen Atalay, Evren Uzer, Mert Veznikli

Purpose: This study aimed to evaluate the validity of two artificial intelligence (AI)-based bone age assessment programs, BoneXpert and VUNO Med-Bone Age (VUNO), compared with manual assessments using the Greulich-Pyle method in Turkish children.

Methods: This study included a cohort of 292 pediatric cases, ranging in age from 1 to 15 years with an equal gender and number distribution in each age group. Two radiologists, who were unaware of the bone age determined by AI, independently evaluated the bone age. The statistical study involved using the intraclass correlation coefficient (ICC) to measure the level of agreement between the manual and AI-based assessments.

Results: The ICC coefficients for the agreement between the manual measurements of two radiologists indicate almost perfect agreement. When all cases, regardless of gender and age group, were analyzed, an almost perfect positive agreement was observed between the manual and software measurements. When bone age calculations were analyzed separately for boys and girls, no statistically significant differences were found between the two AI-based methods in any subgroup. For boys regardless of age, the ICCs were 0.995 for VUNO and 0.994 for BoneXpert (z = 1.597, P = 0.110), while for girls, the ICCs were 0.994 and 0.995, respectively (z = -1.303, P = 0.193). The overall agreement with manual measurements was high for both VUNO and BoneXpert. In both boys and girls, the agreement remained consistent across different age groups. These findings indicate that both AI-based bone age assessment tools have a high degree of agreement with manual measurements across all age and gender groups, with no significant superiority of one method over the other.

Conclusion: Both BoneXpert and VUNO demonstrated high validity in assessing bone age, with no statistically significant differences between the two methods across gender or pubertal status groups. Notably, this study represents the first evaluation of both BoneXpert and VUNO for bone age assessment in Turkish children, highlighting their potential as reliable and clinically relevant tools for this population.

Clinical significance: Investigating the most suitable AI program for the Turkish population could be clinically significant.

目的:本研究旨在评估两种基于人工智能(AI)的骨龄评估程序--BoneXpert 和 VUNO Med-Bone Age(VUNO)--在土耳其儿童中与使用 Greulich-Pyle 方法进行人工评估的有效性:这项研究包括 292 例儿科病例,年龄从 1 岁到 15 岁不等,每个年龄组的性别和人数分布均等。两名放射科医生在不知道 AI 所确定的骨龄的情况下独立评估了骨龄。统计研究采用类内相关系数(ICC)来衡量人工评估和 AI 评估之间的一致程度:结果:两位放射科医生人工测量结果的 ICC 系数几乎完全一致。在对所有病例(不分男女和年龄组)进行分析时,观察到人工和软件测量结果几乎完全一致。如果将女孩和男孩的骨龄计算分开并分别进行分析,两种基于人工智能的方法在男孩方面没有统计学意义上的显著差异;然而,VUNO 和 BoneXpert 的 ICC 系数分别为 0.990 和 0.982,女孩方面 0.008 的差异具有显著性(z = 2.528,P = 0.012)。因此,与 BoneXpert 相比,VUNO 与人工测量的一致性更高。在青春期前组别中,两种软件包与人工测量结果的一致性差异在女孩中比男孩中更为明显。在女孩 8 岁和男孩 9 岁之后,人工测量结果与两套人工智能软件的一致性相同:结论:BoneXpert 和 VUNO 在评估骨龄方面都表现出很高的有效性。结论:BoneXpert 和 VUNO 在评估骨龄方面都显示出较高的有效性,而且在统计上,VUNO 与人工评估在青春期前女孩中的相关性更高。这些结果表明,VUNO 在确定骨龄方面可能略胜一筹,表明它有可能成为评估土耳其儿童骨龄的一种高度可靠的工具:临床意义:研究最适合土耳其人群的人工智能程序具有重要的临床意义。
{"title":"A comparison of two artificial intelligence-based methods for assessing bone age in Turkish children: BoneXpert and VUNO Med-Bone Age.","authors":"Evrim Özmen, Hande Özen Atalay, Evren Uzer, Mert Veznikli","doi":"10.4274/dir.2024.242790","DOIUrl":"10.4274/dir.2024.242790","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the validity of two artificial intelligence (AI)-based bone age assessment programs, BoneXpert and VUNO Med-Bone Age (VUNO), compared with manual assessments using the Greulich-Pyle method in Turkish children.</p><p><strong>Methods: </strong>This study included a cohort of 292 pediatric cases, ranging in age from 1 to 15 years with an equal gender and number distribution in each age group. Two radiologists, who were unaware of the bone age determined by AI, independently evaluated the bone age. The statistical study involved using the intraclass correlation coefficient (ICC) to measure the level of agreement between the manual and AI-based assessments.</p><p><strong>Results: </strong>The ICC coefficients for the agreement between the manual measurements of two radiologists indicate almost perfect agreement. When all cases, regardless of gender and age group, were analyzed, an almost perfect positive agreement was observed between the manual and software measurements. When bone age calculations were analyzed separately for boys and girls, no statistically significant differences were found between the two AI-based methods in any subgroup. For boys regardless of age, the ICCs were 0.995 for VUNO and 0.994 for BoneXpert (z = 1.597, <i>P</i> = 0.110), while for girls, the ICCs were 0.994 and 0.995, respectively (z = -1.303, <i>P</i> = 0.193). The overall agreement with manual measurements was high for both VUNO and BoneXpert. In both boys and girls, the agreement remained consistent across different age groups. These findings indicate that both AI-based bone age assessment tools have a high degree of agreement with manual measurements across all age and gender groups, with no significant superiority of one method over the other.</p><p><strong>Conclusion: </strong>Both BoneXpert and VUNO demonstrated high validity in assessing bone age, with no statistically significant differences between the two methods across gender or pubertal status groups. Notably, this study represents the first evaluation of both BoneXpert and VUNO for bone age assessment in Turkish children, highlighting their potential as reliable and clinically relevant tools for this population.</p><p><strong>Clinical significance: </strong>Investigating the most suitable AI program for the Turkish population could be clinically significant.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"630-635"},"PeriodicalIF":1.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrieval-augmented generation for answering Breast Imaging Reporting and Data System (BI-RADS)-related questions with large language models. 使用大型语言模型回答乳腺成像报告和数据系统(BI-RADS)相关问题的检索增强生成。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-06 Epub Date: 2025-05-20 DOI: 10.4274/dir.2025.253272
Esat Kaba
{"title":"Retrieval-augmented generation for answering Breast Imaging Reporting and Data System (BI-RADS)-related questions with large language models.","authors":"Esat Kaba","doi":"10.4274/dir.2025.253272","DOIUrl":"10.4274/dir.2025.253272","url":null,"abstract":"","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"566-567"},"PeriodicalIF":1.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-pulmonary postoperative complications of cardiothoracic surgery. 心胸外科术后非肺并发症。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-11-06 Epub Date: 2025-07-21 DOI: 10.4274/dir.2025.253354
Furkan Ufuk, İclal Ocak, Lydia Chelala, Luis Landeras

Cardiothoracic surgery, including coronary artery bypass grafting, valve replacement, and transplantation, has considerably advanced, improving patient survival and outcomes. However, non-pulmonary postoperative complications remain a major concern, contributing to morbidity and mortality. These complications encompass cardiovascular events, vascular injuries, infections, and device-related issues that can severely impact recovery. Early diagnosis and timely intervention are crucial to mitigating risks and improving patient outcomes. Advanced imaging modalities such as computed tomography, magnetic resonance imaging, and echocardiography play a pivotal role in identifying and characterizing complications before clinical deterioration occurs. This review highlights the spectrum of acute non-pulmonary complications following cardiothoracic surgery, emphasizing the diagnostic value of imaging in guiding clinical decision-making. By improving the awareness of imaging findings associated with postoperative complications, radiologists and clinicians can facilitate early detection, enabling prompt surgical or medical interventions. A multidisciplinary approach that integrates imaging surveillance with clinical assessment is essential for optimizing patient care and reducing long-term morbidity.

包括冠状动脉旁路移植术、瓣膜置换术和移植在内的心胸外科手术已经取得了相当大的进步,提高了患者的生存率和预后。然而,非肺术后并发症仍然是一个主要问题,导致发病率和死亡率。这些并发症包括严重影响康复的心血管事件、血管损伤、感染和器械相关问题。早期诊断和及时干预对于减轻风险和改善患者预后至关重要。先进的成像方式,如计算机断层扫描、磁共振成像和超声心动图在临床恶化发生前识别和表征并发症方面起着关键作用。本文综述了心胸外科手术后急性非肺并发症的谱,强调了影像学在指导临床决策中的诊断价值。通过提高对与术后并发症相关的影像学发现的认识,放射科医生和临床医生可以促进早期发现,从而及时进行手术或医疗干预。综合影像学监测与临床评估的多学科方法对于优化患者护理和降低长期发病率至关重要。
{"title":"Non-pulmonary postoperative complications of cardiothoracic surgery.","authors":"Furkan Ufuk, İclal Ocak, Lydia Chelala, Luis Landeras","doi":"10.4274/dir.2025.253354","DOIUrl":"10.4274/dir.2025.253354","url":null,"abstract":"<p><p>Cardiothoracic surgery, including coronary artery bypass grafting, valve replacement, and transplantation, has considerably advanced, improving patient survival and outcomes. However, non-pulmonary postoperative complications remain a major concern, contributing to morbidity and mortality. These complications encompass cardiovascular events, vascular injuries, infections, and device-related issues that can severely impact recovery. Early diagnosis and timely intervention are crucial to mitigating risks and improving patient outcomes. Advanced imaging modalities such as computed tomography, magnetic resonance imaging, and echocardiography play a pivotal role in identifying and characterizing complications before clinical deterioration occurs. This review highlights the spectrum of acute non-pulmonary complications following cardiothoracic surgery, emphasizing the diagnostic value of imaging in guiding clinical decision-making. By improving the awareness of imaging findings associated with postoperative complications, radiologists and clinicians can facilitate early detection, enabling prompt surgical or medical interventions. A multidisciplinary approach that integrates imaging surveillance with clinical assessment is essential for optimizing patient care and reducing long-term morbidity.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":"576-590"},"PeriodicalIF":1.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12591356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Diagnostic and interventional radiology
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