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Meta-research on reporting guidelines for artificial intelligence: are authors and reviewers encouraged enough in radiology, nuclear medicine, and medical imaging journals? 关于人工智能报告指南的元研究:放射学、核医学和医学影像期刊对作者和审稿人的鼓励是否足够?
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-09 Epub Date: 2024-02-20 DOI: 10.4274/dir.2024.232604
Burak Koçak, Ali Keleş, Fadime Köse

Purpose: To determine how radiology, nuclear medicine, and medical imaging journals encourage and mandate the use of reporting guidelines for artificial intelligence (AI) in their author and reviewer instructions.

Methods: The primary source of journal information and associated citation data used was the Journal Citation Reports (June 2023 release for 2022 citation data; Clarivate Analytics, UK). The first- and second-quartile journals indexed in the Science Citation Index Expanded and the Emerging Sources Citation Index were included. The author and reviewer instructions were evaluated by two independent readers, followed by an additional reader for consensus, with the assistance of automatic annotation. Encouragement and submission requirements were systematically analyzed. The reporting guidelines were grouped as AI-specific, related to modeling, and unrelated to modeling.

Results: Out of 102 journals, 98 were included in this study, and all of them had author instructions. Only five journals (5%) encouraged the authors to follow AI-specific reporting guidelines. Among these, three required a filled-out checklist. Reviewer instructions were found in 16 journals (16%), among which one journal (6%) encouraged the reviewers to follow AI-specific reporting guidelines without submission requirements. The proportions of author and reviewer encouragement for AI-specific reporting guidelines were statistically significantly lower compared with those for other types of guidelines (P < 0.05 for all).

Conclusion: The findings indicate that AI-specific guidelines are not commonly encouraged and mandated (i.e., requiring a filled-out checklist) by these journals, compared with guidelines related to modeling and unrelated to modeling, leaving vast space for improvement. This meta-research study hopes to contribute to the awareness of the imaging community for AI reporting guidelines and ignite large-scale group efforts by all stakeholders, making AI research less wasteful.

Clinical significance: This meta-research highlights the need for improved encouragement of AI-specific guidelines in radiology, nuclear medicine, and medical imaging journals. This can potentially foster greater awareness among the AI community and motivate various stakeholders to collaborate to promote more efficient and responsible AI research reporting practices.

目的:确定放射学、核医学和医学影像期刊如何在其作者和审稿人说明中鼓励和规定使用人工智能(AI)报告指南:期刊信息和相关引文数据的主要来源是《期刊引文报告》(2023 年 6 月发布的 2022 年引文数据;英国 Clarivate Analytics 公司)。收录的期刊包括《科学引文索引扩展版》和《新兴资源引文索引》收录的第一和第二梯队期刊。作者和审稿人说明由两位独立读者进行评估,然后由另一位读者达成共识,并辅以自动注释。对鼓励和投稿要求进行了系统分析。报告指南分为人工智能专用、与建模相关和与建模无关三类:在 102 种期刊中,有 98 种被纳入本研究,所有期刊都有作者须知。只有五种期刊(5%)鼓励作者遵循人工智能特定的报告指南。其中,3 种期刊要求填写核对表。16种期刊(16%)有审稿人须知,其中1种期刊(6%)鼓励审稿人遵循人工智能特定报告指南,但无投稿要求。与其他类型的指南相比,人工智能特定报告指南的作者和审稿人鼓励比例在统计学上明显较低(P < 0.05):研究结果表明,与建模相关和非建模相关指南相比,这些期刊并不普遍鼓励和强制要求(即要求填写核对表)针对人工智能的指南,因此还有很大的改进空间。这项荟萃研究希望有助于提高成像界对人工智能报告指南的认识,并激发所有利益相关者的大规模群策群力,使人工智能研究减少浪费:这项荟萃研究强调了在放射学、核医学和医学影像期刊中加强鼓励人工智能特定指南的必要性。这有可能提高人工智能界的认识,并激励各利益相关方合作,促进更高效、更负责任的人工智能研究报告实践。
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引用次数: 0
Burnout and the role of mentorship for radiology trainees and early career radiologists 放射科受训人员和早期职业放射科医生的职业倦怠与导师的作用。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-09 Epub Date: 2024-06-05 DOI: 10.4274/dir.2024.242825
Richard J Fagan, Dane Eskildsen, Tara Catanzano, Rachel Stanietzky, Serageldin Kamel, Mohamed Eltaher, Khaled M Elsayes

Burnout is a widespread issue among physicians, including radiologists and radiology trainees. Long hours, isolation, and substantial stress levels contribute to healthcare workers experiencing a substantially higher rate of burnout compared with other professionals. Resident physicians, continuously exposed to stressors such as new clinical situations and performance feedback, are particularly susceptible. Mentorship has proven to be an effective strategy in mitigating burnout. Various mentorship delivery models exist, all aiming to have mentors serve as role models to mentees, thereby alleviating stress and anxiety. Physician groups and healthcare enterprises have actively implemented these programs, recognizing them as both successful and cost-effective. This article explores different mentorship models, their implementation processes, and the effectiveness of these programs as a standard component of academic departments.

职业倦怠是包括放射科医生和放射科实习生在内的医生中普遍存在的问题。与其他专业人员相比,长时间工作、与世隔绝和巨大的压力使医护人员的职业倦怠率大大增加。住院医生不断面临新的临床环境和绩效反馈等压力,尤其容易产生倦怠感。事实证明,导师制是减轻职业倦怠的有效策略。现有各种导师制模式,其目的都是让导师成为被指导者的榜样,从而减轻压力和焦虑。医生团体和医疗保健企业积极实施这些计划,认为它们既成功又具有成本效益。本文探讨了不同的导师制模式、其实施过程以及这些计划作为学术部门标准组成部分的有效性。
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引用次数: 0
A comparison of two artificial intelligence-based methods for assessing bone age in Turkish children: BoneXpert and VUNO Med-Bone Age. 比较两种基于人工智能的土耳其儿童骨龄评估方法:BoneXpert 和 VUNO Med-Bone Age。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-02 DOI: 10.4274/dir.2024.242790
Evrim Özmen, Hande Özen Atalay, Evren Uzer, Mert Veznikli

Purpose: This study aimed to evaluate the validity of two artificial intelligence (AI)-based bone age assessment programs, BoneXpert and VUNO Med-Bone Age (VUNO), compared with manual assessments using the Greulich-Pyle method in Turkish children.

Methods: This study included a cohort of 292 pediatric cases, ranging in age from 1 to 15 years with an equal gender and number distribution in each age group. Two radiologists, who were unaware of the bone age determined by AI, independently evaluated the bone age. The statistical study involved using the intraclass correlation coefficient (ICC) to measure the level of agreement between the manual and AI-based assessments.

Results: The ICC coefficients for the agreement between the manual measurements of two radiologists indicate almost perfect agreement. When all cases, regardless of gender and age group, were analyzed, a nearly perfect positive agreement was observed between the manual and software measurements. When bone age calculations were separated and analyzed separately for girls and boys, there was no statistically significant difference between the two AI-based methods for boys; however, ICC coefficients of 0.990 and 0.982 were calculated for VUNO and BoneXpert, respectively, and this difference of 0.008 was significant (z = 2.528, P = 0.012) for girls. Accordingly, VUNO showed higher agreement with manual measurements compared with BoneXpert. The difference between the agreements demonstrated by the two software packages with manual measurements in the prepubescent group was much more pronounced in girls compared with boys. After the age of 8 years for girls and 9 years for boys, the agreement between manual measurements and both AI software packages was equal.

Conclusion: Both BoneXpert and VUNO showed high validity in assessing bone age. Furthermore, VUNO has a statistically higher correlation with manual assessment in prepubertal girls. These results suggest that VUNO may be slightly more effective in determining bone age, indicating its potential as a highly reliable tool for bone age assessment in Turkish children.

Clinical significance: Investigating the most suitable AI program for the Turkish population could be clinically significant.

目的:本研究旨在评估两种基于人工智能(AI)的骨龄评估程序--BoneXpert 和 VUNO Med-Bone Age(VUNO)--在土耳其儿童中与使用 Greulich-Pyle 方法进行人工评估的有效性:这项研究包括 292 例儿科病例,年龄从 1 岁到 15 岁不等,每个年龄组的性别和人数分布均等。两名放射科医生在不知道 AI 所确定的骨龄的情况下独立评估了骨龄。统计研究采用类内相关系数(ICC)来衡量人工评估和 AI 评估之间的一致程度:结果:两位放射科医生人工测量结果的 ICC 系数几乎完全一致。在对所有病例(不分男女和年龄组)进行分析时,观察到人工和软件测量结果几乎完全一致。如果将女孩和男孩的骨龄计算分开并分别进行分析,两种基于人工智能的方法在男孩方面没有统计学意义上的显著差异;然而,VUNO 和 BoneXpert 的 ICC 系数分别为 0.990 和 0.982,女孩方面 0.008 的差异具有显著性(z = 2.528,P = 0.012)。因此,与 BoneXpert 相比,VUNO 与人工测量的一致性更高。在青春期前组别中,两种软件包与人工测量结果的一致性差异在女孩中比男孩中更为明显。在女孩 8 岁和男孩 9 岁之后,人工测量结果与两套人工智能软件的一致性相同:结论:BoneXpert 和 VUNO 在评估骨龄方面都表现出很高的有效性。结论:BoneXpert 和 VUNO 在评估骨龄方面都显示出较高的有效性,而且在统计上,VUNO 与人工评估在青春期前女孩中的相关性更高。这些结果表明,VUNO 在确定骨龄方面可能略胜一筹,表明它有可能成为评估土耳其儿童骨龄的一种高度可靠的工具:临床意义:研究最适合土耳其人群的人工智能程序具有重要的临床意义。
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引用次数: 0
Feasibility study of computed high b-value diffusion-weighted magnetic resonance imaging for pediatric posterior fossa tumors. 计算高b值扩散加权磁共振成像治疗小儿后窝肿瘤的可行性研究。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-02 DOI: 10.4274/dir.2024.242720
Semra Delibalta, Barış Genç, Meltem Ceyhan Bilgici, Kerim Aslan

Purpose: To evaluate the diagnostic efficacy of computed diffusion-weighted imaging (DWI) in pediatric posterior fossa tumors generated using high b-values.

Methods: We retrospectively performed our study on 32 pediatric patients who had undergone brain magnetic resonance imaging for a posterior fossa tumor between January 2016 and January 2022. The DWIs were evaluated for each patient by two blinded radiologists. The computed DWI (cDWI) was mathematically derived using a mono-exponential model from images with b = 0 and 1,000 s/mm2 and high b-values of 1,500, 2,000, 3,000, and 5,000 s/mm2. The posterior fossa tumors were divided into two groups, low grade and high grade, and the tumor/thalamus signal intensity (SI) ratios were compared. The Mann-Whitney U test and receiver operating characteristic (ROC) curves were used to compare the diagnostic performance of the acquired DWI (DWI1000), apparent diffusion coefficient (ADC)1000 maps, and cDWI (cDWI1500, cDWI2000, cDWI3000, and cDWI5000).

Results: The comparison of the two tumor groups revealed that the tumor/thalamus SI ratio on the DWI1000 and cDWI (cDWI1500, cDWI2000, cDWI3000, and cDWI5000) was statistically significantly higher in high-grade tumors (P < 0.001). In the ROC curve analysis, higher sensitivity and specificity were detected in the cDWI1500, cDWI2000, cDWI3000, and ADC1000 maps (100%, 90.90%) compared with the DWI1000 (80%, 81.80%). cDWI3000 had the highest area under the curve (AUC) value compared with other parameters (AUC: 0.976).

Conclusion: cDWI generated using high b-values was successful in differentiating between low-grade and high-grade posterior fossa tumors without increasing imaging time.

Clinical significance: cDWI created using high b-values can provide additional information about tumor grade in pediatric posterior fossa tumors without requiring additional imaging time.

目的:评估使用高b值的计算弥散加权成像(DWI)对小儿后窝肿瘤的诊断效果:我们对2016年1月至2022年1月期间因后窝肿瘤接受脑磁共振成像的32名儿科患者进行了回顾性研究。每名患者的 DWI 均由两名双盲放射科医生进行评估。计算的 DWI(cDWI)使用单指数模型从 b = 0 和 1,000 s/mm2 以及高 b 值(1,500、2,000、3,000 和 5,000 s/mm2)的图像中进行数学推导。将后窝肿瘤分为低级别和高级别两组,并比较肿瘤/丘脑信号强度(SI)比率。采用曼-惠特尼 U 检验和接收器操作特征曲线(ROC)比较获得的 DWI(DWI1000)、表观弥散系数(ADC)1000 图和 cDWI(cDWI1500、cDWI2000、cDWI3000 和 cDWI5000)的诊断性能:对两组肿瘤进行比较后发现,DWI1000 和 cDWI(cDWI1500、cDWI2000、cDWI3000 和 cDWI5000)上的肿瘤/thalamus SI 比值在统计学上显著高于高级别肿瘤(P < 0.001)。在 ROC 曲线分析中,与 DWI1000(80%,81.80%)相比,cDWI1500、cDWI2000、cDWI3000 和 ADC1000 图谱的灵敏度和特异性更高(100%,90.90%)。结论:使用高b值生成的cDWI能成功区分低级别和高级别后窝肿瘤,且不增加成像时间。临床意义:使用高b值生成的cDWI能提供有关小儿后窝肿瘤级别的额外信息,且不需要额外的成像时间。
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引用次数: 0
A retrospective evaluation of the potential of ChatGPT in the accurate diagnosis of acute stroke. 回顾性评估 ChatGPT 在准确诊断急性中风方面的潜力。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-02 DOI: 10.4274/dir.2024.242892
Beyza Nur Kuzan, İsmail Meşe, Servan Yaşar, Taha Yusuf Kuzan
<p><strong>Purpose: </strong>Stroke is a neurological emergency requiring rapid, accurate diagnosis to prevent severe consequences. Early diagnosis is crucial for reducing morbidity and mortality. Artificial intelligence (AI) diagnosis support tools, such as Chat Generative Pre-trained Transformer (ChatGPT), offer rapid diagnostic advantages. This study assesses ChatGPT's accuracy in interpreting diffusion-weighted imaging (DWI) for acute stroke diagnosis.</p><p><strong>Methods: </strong>A retrospective analysis was conducted to identify the presence of stroke using DWI and apparent diffusion coefficient (ADC) map images. Patients aged >18 years who exhibited diffusion restriction and had a clinically explainable condition were included in the study. Patients with artifacts that affected image homogeneity, accuracy, and clarity, as well as those who had undergone previous surgery or had a history of stroke, were excluded from the study. ChatGPT was asked four consecutive questions regarding the identification of the magnetic resonance imaging (MRI) sequence, the demonstration of diffusion restriction on the ADC map after sequence recognition, and the identification of hemispheres and specific lobes. Each question was repeated 10 times to ensure consistency. Senior radiologists subsequently verified the accuracy of ChatGPT's responses, classifying them as either correct or incorrect. We assumed a response to be incorrect if it was partially correct or suggested multiple answers. These responses were systematically recorded. We also recorded non-responses from ChatGPT-4V when it failed to provide an answer to a query. We assessed ChatGPT-4V's performance by calculating the number and percentage of correct responses, incorrect responses, and non-responses across all images and questions, a metric known as "accuracy." ChatGPT-4V was considered successful if it answered ≥80% of the examples correctly.</p><p><strong>Results: </strong>A total of 530 diffusion MRI, of which 266 were stroke images and 264 were normal, were evaluated in the study. For the initial query identifying MRI sequence type, ChatGPT-4V's accuracy was 88.3% for stroke and 90.1% for normal images. For detecting diffusion restriction, ChatGPT-4V had an accuracy of 79.5% for stroke images, with a 15% false positive rate for normal images. Regarding identifying the brain or cerebellar hemisphere involved, ChatGPT-4V correctly identified the hemisphere in 26.2% of stroke images. For identifying the specific brain lobe or cerebellar area affected, ChatGPT-4V had a 20.4% accuracy for stroke images. The diagnostic sensitivity of ChatGPT-4V in acute stroke was found to be 79.57%, with a specificity of 84.87%, a positive predictive value of 83.86%, a negative predictive value of 80.80%, and a diagnostic odds ratio of 21.86.</p><p><strong>Conclusion: </strong>Despite limitations, ChatGPT shows potential as a supportive tool for healthcare professionals in interpreting diffusion examinations in
目的:中风是一种神经系统急症,需要快速、准确的诊断,以防止严重后果的发生。早期诊断对于降低发病率和死亡率至关重要。人工智能(AI)诊断支持工具,如 Chat Generative Pre-trained Transformer(ChatGPT),具有快速诊断的优势。本研究评估了 ChatGPT 在急性卒中诊断中解释弥散加权成像(DWI)的准确性:方法:对使用 DWI 和表观弥散系数(ADC)图进行脑卒中诊断的患者进行回顾性分析。研究纳入了年龄大于 18 岁、表现出弥散受限且临床可解释的患者。有影响图像均匀性、准确性和清晰度的伪影的患者,以及既往接受过手术或有中风病史的患者被排除在研究之外。ChatGPT 被连续问了四个问题,涉及磁共振成像(MRI)序列的识别、序列识别后 ADC 图上弥散限制的显示以及半球和特定脑叶的识别。每个问题重复 10 次,以确保一致性。资深放射科医生随后会核实 ChatGPT 回答的准确性,并将其分为正确或错误。如果回答部分正确或提出了多个答案,我们就认为该回答不正确。我们系统地记录了这些回复。我们还记录了 ChatGPT-4V 在未能提供查询答案时的非回复。我们通过计算所有图像和问题中正确回答、错误回答和未回答的数量和百分比来评估 ChatGPT-4V 的性能,这一指标被称为 "准确性"。如果 ChatGPT-4V 能正确回答≥80% 的示例,则被认为是成功的:研究共评估了 530 张弥散核磁共振成像,其中 266 张为中风图像,264 张为正常图像。在识别磁共振成像序列类型的初始查询中,ChatGPT-4V 对中风图像的准确率为 88.3%,对正常图像的准确率为 90.1%。在检测弥散限制方面,ChatGPT-4V 对脑卒中图像的准确率为 79.5%,对正常图像的误判率为 15%。在识别涉及的大脑或小脑半球方面,ChatGPT-4V 在 26.2% 的中风图像中正确识别了半球。在识别受影响的特定脑叶或小脑区域方面,ChatGPT-4V 对中风图像的准确率为 20.4%。ChatGPT-4V 对急性中风的诊断敏感性为 79.57%,特异性为 84.87%,阳性预测值为 83.86%,阴性预测值为 80.80%,诊断几率比为 21.86:尽管存在局限性,但 ChatGPT 显示出作为医护人员解释脑卒中病例弥散检查的辅助工具的潜力,及时诊断至关重要:临床意义:ChatGPT 可在卒中病例的各个方面发挥重要作用,如风险评估、早期诊断和治疗计划。
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引用次数: 0
Quadratus lumborum block for procedural and postprocedural analgesia in renal cell carcinoma percutaneous cryoablation. 肾细胞癌经皮冷冻消融术中用于术中和术后镇痛的腰四肌阻滞。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-02 DOI: 10.4274/dir.2024.232100
Saman Fouladirad, Jasper Yoo, Behrang Homayoon, Jun Wang, Pedro Lourenço

This study assesses the efficacy of the quadratus lumborum block (QLB) in the management of procedural and periprocedural pain associated with small renal mass cryoablation. To the best of our knowledge, this is the first study that examines the use of QLB for pain management during percutaneous cryoablation of renal cell carcinoma (RCC). A single-center retrospective review was conducted for patients who underwent cryoablation for RCC with QLB between October 2020 and October 2021. The primary study endpoint included a total dose of procedural conscious sedation and administered, postprocedural analgesia. Technical success in cryoablation was achieved in every case. No patients required additional analgesic during or after the procedure, and no complications resulted from the use of the QLB. The QLB procedure appears to be an effective locoregional block for the management of procedural and periprocedural pain associated with renal mass cryoablation.

本研究评估了腰方肌阻滞(QLB)在治疗与肾脏小肿块冷冻消融术相关的术中和围术期疼痛方面的疗效。据我们所知,这是第一项对肾细胞癌(RCC)经皮冷冻消融术中使用 QLB 进行疼痛治疗的研究。我们对 2020 年 10 月至 2021 年 10 月期间接受冷冻消融术治疗 RCC 并使用 QLB 的患者进行了单中心回顾性研究。主要研究终点包括术中意识镇静和术后镇痛的总剂量。每个病例都取得了冷冻消融的技术成功。没有患者在术中或术后需要额外的镇痛剂,也没有因使用 QLB 而出现并发症。QLB程序似乎是一种有效的局部阻滞方法,可用于治疗与肾脏肿块冷冻消融术相关的术中和围术期疼痛。
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引用次数: 0
Artificial intelligence in musculoskeletal applications: a primer for radiologists. 人工智能在肌肉骨骼领域的应用:放射科医生入门指南。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-19 DOI: 10.4274/dir.2024.242830
Michelle W Tong, Jiamin Zhou, Zehra Akkaya, Sharmila Majumdar, Rupsa Bhattacharjee

As an umbrella term, artificial intelligence (AI) covers machine learning and deep learning. This review aimed to elaborate on these terms to act as a primer for radiologists to learn more about the algorithms commonly used in musculoskeletal radiology. It also aimed to familiarize them with the common practices and issues in the use of AI in this domain.

作为一个总括术语,人工智能(AI)包括机器学习和深度学习。本综述旨在详细阐述这些术语,为放射科医生了解肌肉骨骼放射学常用算法提供入门指南。它还旨在让放射科医生熟悉人工智能在该领域应用的常见做法和问题。
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引用次数: 0
Detection of synovial inflammation in the sacroiliac joint space through intravoxel incoherent motion imaging: an alternative to contrast agents. 通过体外非相干运动成像检测骶髂关节间隙的滑膜炎症:造影剂的替代品。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-19 DOI: 10.4274/dir.2024.242749
Murat Ağırlar, Barış Genç, Aysu Başak Özbalcı
<p><strong>Purpose: </strong>We investigated the diagnostic accuracy of simplified intravoxel incoherent motion (IVIM) imaging for detecting synovial inflammation in the sacroiliac joint (SIJ) in a population with active sacroiliitis.</p><p><strong>Methods: </strong>In accordance with the Assessment of Spondyloarthritis International Society criteria, 86 SIJs of 46 patients with active sacroiliitis were included in this retrospective study conducted between November 2020 and January 2022. Based on T1-weighted post-gadolinium images, the SIJs were divided into two groups: synovial inflammation positive (SIP) (n = 28) and synovial inflammation negative (SIN) (n = 58). Synovial areas in the SIJ space were independently and blindly reviewed for the presence of inflammation by two radiologists with differing levels of expertise in radiology. Using four b values, apparent diffusion coefficient (ADC)= ADC (0, 800) and the simplified 3T IVIM method parameters true diffusion coefficient (D<sub>1</sub>)= ADC (50, 800), D= ADC (400, 800), f<sub>1</sub>= f (0, 50, 800), f<sub>2</sub>= f (0, 400, 800), pseudodiffusion coefficient (D*)= D* (0, 50, 400, 800), ADC<sub>low</sub> = ADC (0, 50), and ADC<sub>diff</sub>= ADC<sub>low</sub> - D were generated voxel by voxel for each patient. The IVIM and ADC parameters at the SIN and SIP joints were compared.</p><p><strong>Results: </strong>The D parameter was significantly increased in SIP areas (1.23 ± 0.34 × 10<sup>-3</sup> mm<sup>2</sup>/s) compared with SIN areas (1.02 ± 0.16 × 10<sup>-3</sup> mm<sup>2</sup>/s) (<i>P</i> = 0.004). Conversely, the D* parameter was significantly decreased in SIP areas (21.78 ± 3.77 × 10<sup>-3</sup> mm<sup>2</sup>/s) compared with SIN areas (16.19 ± 4.58 × 10<sup>-3</sup> mm<sup>2</sup>/s) (<i>P</i> < 0.001). When the optimal cut-off value of 1.11 × 10<sup>-3</sup> mm<sup>2</sup>/s was selected, the sensitivity for the D value was 71% and the specificity was 72% [area under the curve (AUC): 0.716)]. When the optimal cut-off value of 21.06 × 10<sup>-3</sup> mm<sup>2</sup>/s was selected, the sensitivity for the D* value was 78.6%, and the specificity was 79.3% (AUC: 0.829). The interclass correlation coefficient was excellent for f<sub>1</sub>, f<sub>2</sub> D*, D, and ADC<sub>diff</sub>, good for ADC<sub>low</sub> and D<sub>1</sub>, but reasonable for ADC.</p><p><strong>Conclusion: </strong>The presence of synovial inflammation in the SIJ can be evaluated with high sensitivity and specificity using only four b values through the simplified IVIM method without the need for a contrast agent.</p><p><strong>Clinical significance: </strong>IVIM imaging is a technique that allows us to gain insights into tissue perfusion without the administration of contrast agents, utilizing diffusion-weighted images. In this study, for the first time, we demonstrated the potential of detecting synovial inflammation in the SIJ using IVIM, specifically through the pseudodiffusion (D*) parameter, without
目的:我们研究了简化体素内非相干运动(IVIM)成像在活动性骶髂关节炎人群中检测骶髂关节(SIJ)滑膜炎症的诊断准确性:根据脊柱关节炎国际协会的评估标准,这项于2020年11月至2022年1月进行的回顾性研究纳入了46名活动性骶髂关节炎患者的86个骶髂关节。根据 T1 加权钆后图像,SIJ 被分为两组:滑膜炎症阳性组(SIP)(28 人)和滑膜炎症阴性组(SIN)(58 人)。SIJ 间隙中的滑膜区域由两名放射学专业水平不同的放射科医生进行独立盲检,以确定是否存在炎症。使用四个 b 值,表观扩散系数(ADC)= ADC(0,800)和简化的 3T IVIM 方法参数真实扩散系数(D1)= ADC(50,800),D= ADC(400,800)、f1= f(0,50,800),f2= f(0,400,800),假扩散系数(D*)= D*(0,50,400,800),ADClow= ADC(0,50),ADCdiff= ADClow - D。对 SIN 和 SIP 关节处的 IVIM 和 ADC 参数进行比较:与 SIN 区域(1.02 ± 0.16 × 10-3 mm2/s)相比,SIP 区域的 D 参数(1.23 ± 0.34 × 10-3 mm2/s)明显增加(P = 0.004)。相反,与 SIN 区域(16.19 ± 4.58 × 10-3 mm2/s)相比,SIP 区域的 D* 参数(21.78 ± 3.77 × 10-3 mm2/s)明显降低(P < 0.001)。当选择最佳临界值 1.11 × 10-3 mm2/s 时,D 值的灵敏度为 71%,特异度为 72% [曲线下面积 (AUC): 0.716)]。当选择最佳截断值 21.06 × 10-3 mm2/s 时,D* 值的灵敏度为 78.6%,特异度为 79.3%(AUC:0.829)。f1、f2 D*、D和ADCdiff的类间相关系数极佳,ADClow和D1的类间相关系数良好,但ADC的类间相关系数尚可:结论:通过简化的 IVIM 方法,只需使用四个 b 值就能评估 SIJ 滑膜炎症的存在,具有很高的灵敏度和特异性,无需使用造影剂:IVIM成像是一种无需使用造影剂、利用弥散加权成像即可深入了解组织灌注情况的技术。在这项研究中,我们首次证明了利用 IVIM,特别是通过伪扩散(D*)参数,无需造影剂即可检测 SIJ 滑膜炎症的潜力。
{"title":"Detection of synovial inflammation in the sacroiliac joint space through intravoxel incoherent motion imaging: an alternative to contrast agents.","authors":"Murat Ağırlar, Barış Genç, Aysu Başak Özbalcı","doi":"10.4274/dir.2024.242749","DOIUrl":"https://doi.org/10.4274/dir.2024.242749","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;We investigated the diagnostic accuracy of simplified intravoxel incoherent motion (IVIM) imaging for detecting synovial inflammation in the sacroiliac joint (SIJ) in a population with active sacroiliitis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In accordance with the Assessment of Spondyloarthritis International Society criteria, 86 SIJs of 46 patients with active sacroiliitis were included in this retrospective study conducted between November 2020 and January 2022. Based on T1-weighted post-gadolinium images, the SIJs were divided into two groups: synovial inflammation positive (SIP) (n = 28) and synovial inflammation negative (SIN) (n = 58). Synovial areas in the SIJ space were independently and blindly reviewed for the presence of inflammation by two radiologists with differing levels of expertise in radiology. Using four b values, apparent diffusion coefficient (ADC)= ADC (0, 800) and the simplified 3T IVIM method parameters true diffusion coefficient (D&lt;sub&gt;1&lt;/sub&gt;)= ADC (50, 800), D= ADC (400, 800), f&lt;sub&gt;1&lt;/sub&gt;= f (0, 50, 800), f&lt;sub&gt;2&lt;/sub&gt;= f (0, 400, 800), pseudodiffusion coefficient (D*)= D* (0, 50, 400, 800), ADC&lt;sub&gt;low&lt;/sub&gt; = ADC (0, 50), and ADC&lt;sub&gt;diff&lt;/sub&gt;= ADC&lt;sub&gt;low&lt;/sub&gt; - D were generated voxel by voxel for each patient. The IVIM and ADC parameters at the SIN and SIP joints were compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The D parameter was significantly increased in SIP areas (1.23 ± 0.34 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) compared with SIN areas (1.02 ± 0.16 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) (&lt;i&gt;P&lt;/i&gt; = 0.004). Conversely, the D* parameter was significantly decreased in SIP areas (21.78 ± 3.77 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) compared with SIN areas (16.19 ± 4.58 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s) (&lt;i&gt;P&lt;/i&gt; &lt; 0.001). When the optimal cut-off value of 1.11 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s was selected, the sensitivity for the D value was 71% and the specificity was 72% [area under the curve (AUC): 0.716)]. When the optimal cut-off value of 21.06 × 10&lt;sup&gt;-3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/s was selected, the sensitivity for the D* value was 78.6%, and the specificity was 79.3% (AUC: 0.829). The interclass correlation coefficient was excellent for f&lt;sub&gt;1&lt;/sub&gt;, f&lt;sub&gt;2&lt;/sub&gt; D*, D, and ADC&lt;sub&gt;diff&lt;/sub&gt;, good for ADC&lt;sub&gt;low&lt;/sub&gt; and D&lt;sub&gt;1&lt;/sub&gt;, but reasonable for ADC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The presence of synovial inflammation in the SIJ can be evaluated with high sensitivity and specificity using only four b values through the simplified IVIM method without the need for a contrast agent.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;IVIM imaging is a technique that allows us to gain insights into tissue perfusion without the administration of contrast agents, utilizing diffusion-weighted images. In this study, for the first time, we demonstrated the potential of detecting synovial inflammation in the SIJ using IVIM, specifically through the pseudodiffusion (D*) parameter, without ","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating Microsoft Bing with ChatGPT-4 for the assessment of abdominal computed tomography and magnetic resonance images. 评估微软必应与 ChatGPT-4 对腹部计算机断层扫描和磁共振图像的评估。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-19 DOI: 10.4274/dir.2024.232680
Alperen Elek, Duygu Doğa Ekizalioğlu, Ezgi Güler

Purpose: To evaluate the performance of Microsoft Bing with ChatGPT-4 technology in analyzing abdominal computed tomography (CT) and magnetic resonance images (MRI).

Methods: A comparative and descriptive analysis was conducted using the institutional picture archiving and communication systems. A total of 80 abdominal images (44 CT, 36 MRI) that showed various entities affecting the abdominal structures were included. Microsoft Bing's interpretations were compared with the impressions of radiologists in terms of recognition of the imaging modality, identification of the imaging planes (axial, coronal, and sagittal), sequences (in the case of MRI), contrast media administration, correct identification of the anatomical region depicted in the image, and detection of abnormalities.

Results: Microsoft Bing detected that the images were CT scans with 95.4% accuracy (42/44) and that the images were MRI scans with 86.1% accuracy (31/36). However, it failed to detect one CT image (2.3%) and misidentified another CT image as an MRI (2.3%). On the other hand, it also misidentified four MRI as CT images (11.1%) and one as an X-ray (2.7%). Bing achieved an 83.75% success rate in correctly identifying abdominal regions, with 90% accuracy for CT scans (40/44) and 77.7% for MRI scans (28/36). Concerning the identification of imaging planes, Bing achieved a success rate of 95.4% for CT images and 83.3% for MRI. Regarding the identification of MRI sequences (T1-weighted and T2-weighted), the success rate was 68.75%. In the identification of the use of contrast media for CT scans, the success rate was 64.2%. Bing detected abnormalities in 35% of the images but achieved a correct interpretation rate of 10.7% for the definite diagnosis.

Conclusion: While Microsoft Bing, leveraging ChatGPT-4 technology, demonstrates proficiency in basic task identification on abdominal CT and MRI, its inability to reliably interpret abnormalities highlights the need for continued refinement to enhance its clinical applicability.

Clinical significance: The contribution of large language models (LLMs) to the diagnostic process in radiology is still being explored. However, with a comprehensive understanding of their capabilities and limitations, LLMs can significantly support radiologists during diagnosis and improve the overall efficiency of abdominal radiology practices. Acknowledging the limitations of current studies related to ChatGPT in this field, our work provides a foundation for future clinical research, paving the way for more integrated and effective diagnostic tools.

目的:评估微软必应与 ChatGPT-4 技术在分析腹部计算机断层扫描(CT)和磁共振成像(MRI)方面的性能:方法:利用机构图片存档和通信系统进行比较和描述性分析。共纳入了 80 张显示影响腹部结构的各种实体的腹部图像(44 张 CT,36 张 MRI)。微软必应的判读结果与放射科医生的判读结果进行了比较,包括成像方式的识别、成像平面(轴位、冠状位和矢状位)的识别、序列(如果是核磁共振成像)、造影剂的使用、图像中描述的解剖区域的正确识别以及异常的检测:微软必应检测到图像是 CT 扫描的准确率为 95.4%(42/44),检测到图像是 MRI 扫描的准确率为 86.1%(31/36)。不过,它未能检测出一张 CT 图像(2.3%),并将另一张 CT 图像误认为核磁共振图像(2.3%)。另一方面,它还将四张核磁共振图像误认为 CT 图像(11.1%),将一张误认为 X 光(2.7%)。Bing 在正确识别腹部区域方面的成功率为 83.75%,其中 CT 扫描的准确率为 90%(40/44),MRI 扫描的准确率为 77.7%(28/36)。在成像平面的识别方面,Bing 对 CT 图像的识别成功率为 95.4%,对 MRI 图像的识别成功率为 83.3%。在核磁共振成像序列(T1 加权和 T2 加权)的识别方面,成功率为 68.75%。在识别 CT 扫描是否使用造影剂方面,成功率为 64.2%。必应在 35% 的图像中发现了异常,但明确诊断的正确解释率仅为 10.7%:结论:虽然微软必应利用 ChatGPT-4 技术在腹部 CT 和 MRI 的基本任务识别方面表现出色,但它无法可靠地解释异常情况,这突出表明需要不断改进以提高其临床适用性:临床意义:大型语言模型(LLM)对放射学诊断过程的贡献仍在探索之中。然而,只要全面了解其能力和局限性,大语言模型就能在诊断过程中为放射科医生提供重要支持,并提高腹部放射学实践的整体效率。我们的工作承认目前与 ChatGPT 相关的研究在这一领域存在局限性,但我们的工作为未来的临床研究奠定了基础,为更综合、更有效的诊断工具铺平了道路。
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引用次数: 0
Splenic artery embolization in the treatment of blunt splenic injury: single level 1 trauma center experience. 脾动脉栓塞治疗钝性脾损伤:单个一级创伤中心的经验。
IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-11 DOI: 10.4274/dir.2024.242789
Katelyn Gill, Sarah Aleman, Alexandra H Fairchild, Bahri Üstünsöz, Dan Laney, Alison A Smith, Hector Ferral

Purpose: To describe the experience of a single level 1 trauma center in the management of blunt splenic injuries (BSI).

Methods: This is a retrospective study with Institutional Review Board approval. The medical records of 450 patients with BSI treated between January 2016 and December 2022 were reviewed. Seventy-two patients were treated with splenic artery embolization (SAE), met the study criteria, and were eligible for data analysis. Spleen injuries were graded in accordance with the American Association for the Surgery of Trauma Organ Injury Scale. Univariate data analysis was performed, with P < 0.05 considered statistically significant.

Results: The splenic salvage rate was 90.3% (n = 65/72). Baseline demographics were similar between the groups (P > 0.05). Distal embolization with Gelfoam® had similar rates of splenic salvage to proximal embolization with coils (90% vs. 94.1%, P > 0.05). There was no significant difference in the rate of splenic infarction between distal embolization with Gelfoam® (20%, 4/20) and proximal embolization with coils (17.6%, 3/17) (P > 0.05). There was no significant difference in procedure length (68 vs. 75.8 min) or splenic salvage rate (88.5% vs. 92.1%) between proximal and distal embolization (P > 0.05). There was no significant difference in procedure length (69.1 vs. 73.6 min) or splenic salvage rate (93.1% vs. 86.4%) between Gelfoam® and coil embolization (P > 0.05). Combined proximal and distal embolization was associated with a higher rate of splenic abscess formation (25%, 2/8) when compared with proximal (0%, 0/26) or distal (0%, 0/38) embolization alone (P = 0.0003). The rate of asymptomatic and symptomatic splenic infarction was significantly higher in patients embolized at combined proximal and distal locations (P = 0.04, P = 0.01).

Conclusion: The endovascular management of BSI is safe and effective. The overall splenic salvage rate was 90.3%. Distal embolization with Gelfoam® was not associated with higher rates of splenic infarction when compared with proximal embolization with coils. Combined proximal and distal embolization was associated with a higher incidence of splenic infarction and splenic abscess formation.

Clinical significance: Distal splenic embolization with Gelfoam® is safe and may be beneficial in the setting of blunt splenic trauma.

目的:描述一家一级创伤中心在处理钝性脾损伤(BSI)方面的经验:这是一项经机构审查委员会批准的回顾性研究。研究回顾了2016年1月至2022年12月期间收治的450名BSI患者的病历。72名患者接受了脾动脉栓塞(SAE)治疗,符合研究标准,并有资格进行数据分析。脾脏损伤根据美国创伤外科协会器官损伤量表进行分级。进行单变量数据分析,P<0.05为有统计学意义:结果:脾脏挽救率为90.3%(n = 65/72)。两组的基线人口统计学特征相似(P > 0.05)。使用 Gelfoam® 进行远端栓塞与使用线圈进行近端栓塞的脾脏挽救率相似(90% vs. 94.1%,P > 0.05)。使用 Gelfoam® 进行远端栓塞(20%,4/20)和使用线圈进行近端栓塞(17.6%,3/17)的脾梗塞率没有明显差异(P > 0.05)。近端栓塞和远端栓塞在手术时间(68 分钟对 75.8 分钟)和脾脏挽救率(88.5% 对 92.1%)方面没有明显差异(P > 0.05)。Gelfoam® 和线圈栓塞的手术时间(69.1 分钟对 73.6 分钟)和脾脏挽救率(93.1% 对 86.4%)没有明显差异(P > 0.05)。与单纯近端栓塞(0%,0/26)或远端栓塞(0%,0/38)相比,近端和远端联合栓塞与较高的脾脓肿形成率(25%,2/8)相关(P = 0.0003)。在近端和远端联合栓塞的患者中,无症状和有症状脾梗死的发生率明显更高(P = 0.04,P = 0.01):结论:血管内治疗BSI安全有效。结论:血管内治疗 BSI 安全有效,总体脾脏挽救率为 90.3%。与使用线圈的近端栓塞相比,使用 Gelfoam® 的远端栓塞与较高的脾梗塞率无关。近端和远端联合栓塞与较高的脾梗塞和脾脓肿形成率有关:临床意义:使用 Gelfoam® 进行远端脾栓塞是安全的,可能对钝性脾外伤有益。
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Diagnostic and interventional radiology
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