Pub Date : 2023-06-19DOI: 10.24018/ejmed.2023.5.3.1721
Vernon Johnson Moonga, A. Tsarkov, P. Petlovanyi
Introduction: Mental illness is becoming a worldwide concern with at least one in four persons suffering from mental illness in both developed and developing countries. Mental illnesses account for about 14% of the disease burden worldwide and are projected to reach 15% in the future. Readmission to psychiatric wards of patients is one of the biggest challenges in the field of psychiatry and hence reduces the quality of life of individual patients as well as increasing the years of lost life of the patients. Objective: This research aims at determining the factors influencing the readmission of mentally ill adults at Chainama Hills College Hospital (CHCH), Lusaka, Zambia. Method: This was a quantitative cross-sectional study with a sampling of 94 patients, who seek service at CHCH. The data collection was done through a validated questionnaire. The questionnaire included demographic characteristics of patients, health facility factors associated with the readmission of psychiatric patients, and patient-related factors associated with the readmission of mental patients. Data were analyzed and processed using Statistical Package for Social Sciences (SPSS) version 25. Results: The analysis and presentation of results in this research provide relevant evidence that can be used to meet the objective of this research. The results were presented with a 5% level of significance and 95% confidence. The Pearson Chi-square test was used with a (p-value of 0.232). These results have revealed there was no significant difference between the factors influencing the readmission of mentally ill adults. Conclusion: No socio-demographic, factor was found to be strongly associated with readmission of psychiatric adult patients. Single, and unemployed patients were more frequently readmitted than the patients from other social groups. The young patients were readmitted more often than elders. Adult patients who stayed near the health facility were more likely to be readmitted than those who stayed far away. Stress had some association with readmissions.
{"title":"A Descriptive Study on the Factors Influencing Readmission of Mentally Ill Adults at Chainama Hills College Hospital, Lusaka, Zambia","authors":"Vernon Johnson Moonga, A. Tsarkov, P. Petlovanyi","doi":"10.24018/ejmed.2023.5.3.1721","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1721","url":null,"abstract":"\u0000Introduction: Mental illness is becoming a worldwide concern with at least one in four persons suffering from mental illness in both developed and developing countries. Mental illnesses account for about 14% of the disease burden worldwide and are projected to reach 15% in the future. Readmission to psychiatric wards of patients is one of the biggest challenges in the field of psychiatry and hence reduces the quality of life of individual patients as well as increasing the years of lost life of the patients. \u0000\u0000\u0000Objective: This research aims at determining the factors influencing the readmission of mentally ill adults at Chainama Hills College Hospital (CHCH), Lusaka, Zambia.\u0000\u0000\u0000Method: This was a quantitative cross-sectional study with a sampling of 94 patients, who seek service at CHCH. The data collection was done through a validated questionnaire. The questionnaire included demographic characteristics of patients, health facility factors associated with the readmission of psychiatric patients, and patient-related factors associated with the readmission of mental patients. Data were analyzed and processed using Statistical Package for Social Sciences (SPSS) version 25.\u0000\u0000\u0000Results: The analysis and presentation of results in this research provide relevant evidence that can be used to meet the objective of this research. The results were presented with a 5% level of significance and 95% confidence. The Pearson Chi-square test was used with a (p-value of 0.232). These results have revealed there was no significant difference between the factors influencing the readmission of mentally ill adults. \u0000\u0000\u0000Conclusion: No socio-demographic, factor was found to be strongly associated with readmission of psychiatric adult patients. Single, and unemployed patients were more frequently readmitted than the patients from other social groups. The young patients were readmitted more often than elders. Adult patients who stayed near the health facility were more likely to be readmitted than those who stayed far away. Stress had some association with readmissions. \u0000","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133122229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-19DOI: 10.24018/ejmed.2023.5.3.1451
R. Chatterjee, S. Chatterjee, S. Pal, Biswajit Das, Nilanjan Mitra, R. Ghosh
The psychological conditions of healthcare professionals deteriorate during the COVID-19 outbreak, which is effective worldwide. Sexual activity is a natural part of human existence and its effectiveness is recognized as a key indicator of good health and quality of life. In this study, we aimed to analyze the influence of COVID-19 on sexual activity in four recovered male patients. These males showed deterioration in all elements of sexual function. To the best of our knowledge, this is the first study that we are reporting from Kolkata, India, that used validated assessment to document sexual functioning in males following post-COVID-19 illness.
{"title":"A Retrospective Assessment of Male Sexual Dysfunction in COVID-19 Infected Patients: A Witness in Kolkata, India","authors":"R. Chatterjee, S. Chatterjee, S. Pal, Biswajit Das, Nilanjan Mitra, R. Ghosh","doi":"10.24018/ejmed.2023.5.3.1451","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1451","url":null,"abstract":"\u0000The psychological conditions of healthcare professionals deteriorate during the COVID-19 outbreak, which is effective worldwide. Sexual activity is a natural part of human existence and its effectiveness is recognized as a key indicator of good health and quality of life. In this study, we aimed to analyze the influence of COVID-19 on sexual activity in four recovered male patients. These males showed deterioration in all elements of sexual function. To the best of our knowledge, this is the first study that we are reporting from Kolkata, India, that used validated assessment to document sexual functioning in males following post-COVID-19 illness.\u0000","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121492632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-09DOI: 10.34104/ejmhs.023.074079
S. K. Thazha, S. Kotian
One of the most important life transitions for women is menopause, which is accompanied by a number of physiological changes that have long-lasting effects on a woman's quality of life. Several theories have been put up on the signs and symptoms that arise prior to, during, and following the beginning of menopause. These symptoms, together make up the syndrome that significantly affects the women in their post-menopausal life. This review makes an effort to comprehend these symptoms and their associated predisposing factors.
{"title":"A Quick Analysis of Post-Menopause and the Syndrome Related to its Predisposing Factors","authors":"S. K. Thazha, S. Kotian","doi":"10.34104/ejmhs.023.074079","DOIUrl":"https://doi.org/10.34104/ejmhs.023.074079","url":null,"abstract":"One of the most important life transitions for women is menopause, which is accompanied by a number of physiological changes that have long-lasting effects on a woman's quality of life. Several theories have been put up on the signs and symptoms that arise prior to, during, and following the beginning of menopause. These symptoms, together make up the syndrome that significantly affects the women in their post-menopausal life. This review makes an effort to comprehend these symptoms and their associated predisposing factors.","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114964044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-03DOI: 10.24018/ejmed.2023.5.3.1700
K. A. Marin, A. Natali
This study investigated the association of self-reported daily time in sedentary behavior with cardiometabolic risk factors in middle-aged adults living in a Brazilian eastern Amazon city. Middle-aged public civil servant living in Palma’s city participated in this cross-sectional study. Daily sedentary behavior and physical activity were measured, and anthropometric parameters and blood biochemical biomarkers were obtained. The results showed that total daily time in sedentary behavior measured using International Physical Activity Questionnaire associated positively with waist to height ratio [β = 0.008 (95% CI = 0.001; 0.016), p = 0.023] and body adiposity index [β = 0.570 (95% CI = 0.110; 1.020), p = 0.016]; and the time spent in passive transport measured using Longitudinal Aging Study Amsterdam - Sedentary Behavior Questionnaire was positively associated with neck [β = 4.420 (95% CI = 1.360; 7.480), p = 0.005) and waist circumference [β = 7.990 (95% CI = 3.490; 12.500), p = 0.005], waist to hip ratio [β = 0.060 (95% CI = 0.030; 0.100), p = 0.001), conicity index [0.050 (95% CI = 0.010; 0.080), p = 0.002], and the concentrations of triglycerides [β =38.500 (95% CI = 6.640; 70.390), p = 0.019] and insulin [β = 2.490 (95% CI = 1.030; 3.950), p = 0.001]. In conclusion, self-reported sedentary behavior is associated with anthropometric and biochemical risk factors for cardiometabolic diseases in the studied individuals.
这项研究调查了生活在巴西东部亚马逊城市的中年人自我报告的每天久坐行为时间与心脏代谢风险因素的关系。本研究以居住在帕尔马市的中年公务员为研究对象。测量每日久坐行为和体力活动，并获得人体测量参数和血液生化生物标志物。结果显示，使用国际身体活动问卷测量的每天久坐行为的总时间与腰高比呈正相关[β = 0.008 (95% CI = 0.001;0.016)， p = 0.023]和体脂指数[β = 0.570 (95% CI = 0.110;1.020)， p = 0.016];使用阿姆斯特丹纵向衰老研究-久坐行为问卷测量的被动运输时间与颈部呈正相关[β = 4.420 (95% CI = 1.360;7.480)， p = 0.005)和腰围[β = 7.990 (95% CI = 3.490;12.500)， p = 0.005]，腰臀比[β = 0.060 (95% CI = 0.030;0.100)， p = 0.001)，圆锥度指数[0.050](95% CI = 0.010;0.080)， p = 0.002]，甘油三酯浓度[β =38.500 (95% CI = 6.640;70.390)， p = 0.019]和胰岛素[β = 2.490 (95% CI = 1.030;3.950)， p = 0.001]。综上所述，自我报告的久坐行为与研究个体的心脏代谢疾病的人体测量和生化危险因素有关。
{"title":"Sedentary Behavior and Cardiometabolic Risk Factors in Middle-aged Adults Living in A Brazilian Eastern Amazon City: A Cross Sectional Study","authors":"K. A. Marin, A. Natali","doi":"10.24018/ejmed.2023.5.3.1700","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1700","url":null,"abstract":"\u0000This study investigated the association of self-reported daily time in sedentary behavior with cardiometabolic risk factors in middle-aged adults living in a Brazilian eastern Amazon city. Middle-aged public civil servant living in Palma’s city participated in this cross-sectional study. Daily sedentary behavior and physical activity were measured, and anthropometric parameters and blood biochemical biomarkers were obtained. The results showed that total daily time in sedentary behavior measured using International Physical Activity Questionnaire associated positively with waist to height ratio [β = 0.008 (95% CI = 0.001; 0.016), p = 0.023] and body adiposity index [β = 0.570 (95% CI = 0.110; 1.020), p = 0.016]; and the time spent in passive transport measured using Longitudinal Aging Study Amsterdam - Sedentary Behavior Questionnaire was positively associated with neck [β = 4.420 (95% CI = 1.360; 7.480), p = 0.005) and waist circumference [β = 7.990 (95% CI = 3.490; 12.500), p = 0.005], waist to hip ratio [β = 0.060 (95% CI = 0.030; 0.100), p = 0.001), conicity index [0.050 (95% CI = 0.010; 0.080), p = 0.002], and the concentrations of triglycerides [β =38.500 (95% CI = 6.640; 70.390), p = 0.019] and insulin [β = 2.490 (95% CI = 1.030; 3.950), p = 0.001]. In conclusion, self-reported sedentary behavior is associated with anthropometric and biochemical risk factors for cardiometabolic diseases in the studied individuals. \u0000","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132321908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-03DOI: 10.24018/ejmed.2023.5.3.1702
V. Bell, Cídia Rosália Pinho Guina Silva, José Guina, T. Fernandes
Health is central to the development of any country. Despite the efforts and goodwill of the United Nations, the goals established have not been successfully achieved and people in Sub-Saharan Africa (SSA) continue to strive with the same burdens of poverty, employment, malnutrition or hunger, inequality, environmental crisis, access to energy, conflicts and injustice. All these determinants drawback factors may be cause or consequence of a never-ending cycle with enormous impact on individual and community health. In SSA, policy makers, donors, healthcare providers, and academics have paid less attention to chronic diseases than to acute, communicable diseases. Despite severe dysfunctions, Public Health in this region, distinct from immediate medical services, is now engaged in endless struggles, against pathogens, modelling human behaviors, and searching for financing. Parental education, health and welfare, substandard literacy and language communication, access to material assets and other factors may all affect their ability to interpret hazards and risks in key areas of health and nutrition. While some 70% of deaths in Africa result from infectious and parasitic diseases, mortality rates from chronic diseases are higher in SSA than in other parts of the world. Children and adolescents in SSA in their livelihoods experience slow physical growing, inadequate observation and physical development, and a series of biological impairments that amplifies their risk of non-communicable diseases as they mature. Integrated strategies of sound health leadership and community-adapted initiatives are needed and probably engaged constructively with the private sector. Some ambitious new health goals take longer to achieve, but progress can be achieved in stages.
{"title":"Community Health of Children and Adolescents in Sub-Saharan Africa","authors":"V. Bell, Cídia Rosália Pinho Guina Silva, José Guina, T. Fernandes","doi":"10.24018/ejmed.2023.5.3.1702","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1702","url":null,"abstract":"\u0000Health is central to the development of any country. Despite the efforts and goodwill of the United Nations, the goals established have not been successfully achieved and people in Sub-Saharan Africa (SSA) continue to strive with the same burdens of poverty, employment, malnutrition or hunger, inequality, environmental crisis, access to energy, conflicts and injustice. All these determinants drawback factors may be cause or consequence of a never-ending cycle with enormous impact on individual and community health. In SSA, policy makers, donors, healthcare providers, and academics have paid less attention to chronic diseases than to acute, communicable diseases. Despite severe dysfunctions, Public Health in this region, distinct from immediate medical services, is now engaged in endless struggles, against pathogens, modelling human behaviors, and searching for financing. Parental education, health and welfare, substandard literacy and language communication, access to material assets and other factors may all affect their ability to interpret hazards and risks in key areas of health and nutrition. While some 70% of deaths in Africa result from infectious and parasitic diseases, mortality rates from chronic diseases are higher in SSA than in other parts of the world. Children and adolescents in SSA in their livelihoods experience slow physical growing, inadequate observation and physical development, and a series of biological impairments that amplifies their risk of non-communicable diseases as they mature. Integrated strategies of sound health leadership and community-adapted initiatives are needed and probably engaged constructively with the private sector. Some ambitious new health goals take longer to achieve, but progress can be achieved in stages.\u0000","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123713614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-03DOI: 10.24018/ejmed.2023.5.3.1735
David Aondona Daniel, N. Akwaras, Abraham Kohol, Paul Tersur Apande, Fanen Dogoh, Kashimana Tyovenda
Background: Hypertension has increasingly become a public health concern in developing countries. Awareness of blood pressure status in the light of lifestyle modification knowledge and practices is cardinal in the prevention and control of hypertension. Lack of blood pressure status awareness is associated with delayed recognition of hypertension related complications. Aim: This study assessed the determinants of blood pressure status awareness and educated the participants on lifestyle modification practices to prevent hypertension. Method: This was a descriptive cross-sectional study of 103 consecutive consenting adult participants in a market outreach carried out to mark World Family Physicians Day. The questionnaires were interviewer administered. Analysis of data was done with SPSS version 20 and the level of significance was at a p-value of 0.05. Result: Their mean age was 42.4 ± 12.4 years. There were more females 58(56.3%) than males and most of the participants were married, 72(69.9%). Those that had secondary education were 47(45.6%) and most, 95(92.2%) earned a monthly income of ≤₦49.999. Only 37.9% of the participants were aware of their blood pressure status. There was a statistically significant association between those that were not aware of their blood pressure status and those that lack knowledge of lifestyle modification practices, those that do not correctly practice lifestyle modification and those that have negative perception towards hypertension prevention. Furthermore, the participants with above mentioned attributes were less likely to know their blood pressure status. Conclusion: The level of blood pressure status awareness was low, those that lacked knowledge of lifestyle modification, do not practice lifestyle modification and have negative perception toward hypertension prevention were less likely to be aware of their blood pressure status.
背景:高血压已日益成为发展中国家的公共卫生问题。根据生活方式改变的知识和实践来了解血压状况是预防和控制高血压的基础。缺乏血压状态意识与高血压相关并发症的延迟识别有关。目的:本研究评估血压状态意识的决定因素，并教育参与者改变生活方式以预防高血压。方法:这是一项描述性横断面研究，103名连续同意的成年参与者参加了一项市场推广活动，以纪念世界家庭医生日。问卷由采访者填写。数据分析采用SPSS version 20, p值为0.05。结果:患者平均年龄42.4±12.4岁。其中女性58人(56.3%)多于男性，已婚72人(69.9%)。受过中等教育的有47人(45.6%)，大多数95人(92.2%)的月收入≤奈拉49.999。只有37.9%的参与者知道自己的血压状况。不了解自己血压状况的人与缺乏改变生活方式知识的人、没有正确改变生活方式的人与对预防高血压有消极看法的人之间存在统计学上的显著关联。此外，具有上述属性的参与者不太可能知道自己的血压状况。结论:高血压患者的血压状态知晓率较低，缺乏生活方式改变知识、不进行生活方式改变、对高血压预防有消极认知的患者对自己的血压状态知晓率较低。
{"title":"Lifestyle Modification Determinants of Blood Pressure Status Awareness amongst Traders in A Market Community North Central Nigeria","authors":"David Aondona Daniel, N. Akwaras, Abraham Kohol, Paul Tersur Apande, Fanen Dogoh, Kashimana Tyovenda","doi":"10.24018/ejmed.2023.5.3.1735","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1735","url":null,"abstract":"Background: Hypertension has increasingly become a public health concern in developing countries. Awareness of blood pressure status in the light of lifestyle modification knowledge and practices is cardinal in the prevention and control of hypertension. Lack of blood pressure status awareness is associated with delayed recognition of hypertension related complications. \u0000Aim: This study assessed the determinants of blood pressure status awareness and educated the participants on lifestyle modification practices to prevent hypertension. \u0000Method: This was a descriptive cross-sectional study of 103 consecutive consenting adult participants in a market outreach carried out to mark World Family Physicians Day. The questionnaires were interviewer administered. Analysis of data was done with SPSS version 20 and the level of significance was at a p-value of 0.05. \u0000Result: Their mean age was 42.4 ± 12.4 years. There were more females 58(56.3%) than males and most of the participants were married, 72(69.9%). Those that had secondary education were 47(45.6%) and most, 95(92.2%) earned a monthly income of ≤₦49.999. Only 37.9% of the participants were aware of their blood pressure status. There was a statistically significant association between those that were not aware of their blood pressure status and those that lack knowledge of lifestyle modification practices, those that do not correctly practice lifestyle modification and those that have negative perception towards hypertension prevention. Furthermore, the participants with above mentioned attributes were less likely to know their blood pressure status. \u0000Conclusion: The level of blood pressure status awareness was low, those that lacked knowledge of lifestyle modification, do not practice lifestyle modification and have negative perception toward hypertension prevention were less likely to be aware of their blood pressure status.","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"4 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123631855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-03DOI: 10.24018/ejmed.2023.5.3.1699
M. Jaman, Abdullah Al Mamun, Bishal Sharker, Md. Maniruzzaman, Md. Rakib Rased Rana, M. Hasan, Md. Rokibul Hasan Bhuiyan
Globally, Breast cancer is a complex and common disease. 12.5 % of all new annual cancer cases worldwide. In 2020 there were 2.3 million women with breast cancer diagnosed and 685,000 died globally. For long time, breast cancer treatments options include surgery, chemotherapy, hormone therapy and radiotherapy. However adverse effects from treatment options are frequently reported and multidrug resistance, fever, weakness, allergy and the absence of treatment for metastasis are the main issues with breast cancer treatment. Due to their safety, dietary bioactive molecules have become effective tools for the treatment and prevention of cancer cell lines and animal models in recent years. It has been demonstrated that the compunds curcumin, diallyl sulfide, quercetin and gallic acid which are used as Indian spice and widely consumed fruits, suppress the growth of breast cancer cells and trigger apoptosis. The effects of curcumin, diallyl sulfide, quercetin and gallic acid in the combat against breast cancer are covered in this review. These agents have been shown to have effects both in vitro and in vivo.
{"title":"Curcumin, Diallyl Sulphide, Quercetin and Gallic Acid Uses as Anticancer and Therapeutic Agents for Breast Cancer: Current Strategies and Future Perspectives","authors":"M. Jaman, Abdullah Al Mamun, Bishal Sharker, Md. Maniruzzaman, Md. Rakib Rased Rana, M. Hasan, Md. Rokibul Hasan Bhuiyan","doi":"10.24018/ejmed.2023.5.3.1699","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1699","url":null,"abstract":"Globally, Breast cancer is a complex and common disease. 12.5 % of all new annual cancer cases worldwide. In 2020 there were 2.3 million women with breast cancer diagnosed and 685,000 died globally. For long time, breast cancer treatments options include surgery, chemotherapy, hormone therapy and radiotherapy. However adverse effects from treatment options are frequently reported and multidrug resistance, fever, weakness, allergy and the absence of treatment for metastasis are the main issues with breast cancer treatment. Due to their safety, dietary bioactive molecules have become effective tools for the treatment and prevention of cancer cell lines and animal models in recent years. It has been demonstrated that the compunds curcumin, diallyl sulfide, quercetin and gallic acid which are used as Indian spice and widely consumed fruits, suppress the growth of breast cancer cells and trigger apoptosis. The effects of curcumin, diallyl sulfide, quercetin and gallic acid in the combat against breast cancer are covered in this review. These agents have been shown to have effects both in vitro and in vivo.","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127820976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-02DOI: 10.24018/ejmed.2023.5.3.1668
T. Chekrine, M. Bourhafour, C. Moustakbal, Z. Bouchbika, N. Benchakroun, H. Jouhadi, N. Tawfiq, L. Jabri, M. Mahtar, A. Madani, S. Sahraoui
Extranodal Natural Killer T-cell lymphoma, nasal type represent a rare and aggressive entity of the non-Hodgkin's lymphomas. Laryngeal localization is rare and has a poor prognosis. We report the case of a 66-year-old patient who consulted for dyspnea, dysphonia and dysphagia. Endoscopic examination revealed an endo-laryngeal lesion. Anatomopathological study with immunohistochemistry concluded to a peripheral T NK/T-cell lymphoma nasal type. The extension workup was without abnormalities. Induction chemotherapy without anthracyclines was administered followed by conformal radiotherapy with intensity modulation in arctotherapy. Significant advances have been made over the past decade including better clarification of clinical heterogeneity, more accurate classification using imaging modalities, establishment of new prognostic models, and sequential use of anthracycline-free radiotherapy and chemotherapy in early stages and risk-adapted first-line treatment strategies in advanced stages.
{"title":"Laryngeal NK/T Cell Lymphoma, Nasal Type: Case Report and Literature Review","authors":"T. Chekrine, M. Bourhafour, C. Moustakbal, Z. Bouchbika, N. Benchakroun, H. Jouhadi, N. Tawfiq, L. Jabri, M. Mahtar, A. Madani, S. Sahraoui","doi":"10.24018/ejmed.2023.5.3.1668","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1668","url":null,"abstract":"Extranodal Natural Killer T-cell lymphoma, nasal type represent a rare and aggressive entity of the non-Hodgkin's lymphomas. Laryngeal localization is rare and has a poor prognosis. We report the case of a 66-year-old patient who consulted for dyspnea, dysphonia and dysphagia. Endoscopic examination revealed an endo-laryngeal lesion. Anatomopathological study with immunohistochemistry concluded to a peripheral T NK/T-cell lymphoma nasal type. The extension workup was without abnormalities. Induction chemotherapy without anthracyclines was administered followed by conformal radiotherapy with intensity modulation in arctotherapy. Significant advances have been made over the past decade including better clarification of clinical heterogeneity, more accurate classification using imaging modalities, establishment of new prognostic models, and sequential use of anthracycline-free radiotherapy and chemotherapy in early stages and risk-adapted first-line treatment strategies in advanced stages.","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128397477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-02DOI: 10.24018/ejmed.2023.5.3.1634
Abdussemee Abdurrazzaaq, V. Grimah, A. Yakubu
Background: Typhoid intestinal perforation is the most common surgical complication and a significant cause of morbidity and mortality in typhoid fever. Aim: To determine the treatment outcome of patients with typhoid intestinal perforation. Methods: A single-centre retrospective study involving retrieving case notes of all consecutive patients who had surgeries for peritonitis secondary to typhoid intestinal perforation from October 2016 to September 2017. Data were collected with a designed case report form and analysed. Results: Sixty-nine patients had surgeries for typhoid intestinal perforation, of which forty-five (65.2%) were males. The median (range) age of the participants was 10(4-44) years. The commonest complications were surgical site infections 49 (71%) and wound dehiscence 17 (24.6%). The median (range) post-operative hospital stay among the survivors was 13 (7 – 50) days. Enterocutaneous fistula and wound dehiscence were responsible for prolonged hospital stay (x2= 30.126, p value< 0.001 and x2= 45.777, p value< 0.001 respectively). The overall mortality rate was 19 (27.5%). Under-five children had the highest mortality rate 5/15 (33.3%). Mortality was found to be more common among females though the association was not statistically significant (p value = 0.052). Mortality was significantly associated with extended surgical procedures (p value= 0.027). Conclusion: The reported cases of typhoid intestinal perforations at the study centre were high but the mortality rate was comparable to other similar studies in Nigeria. Mortality from typhoid perforation remains high, and the pathology is best prevented
{"title":"Outcome of Typhoid Intestinal Perforation Management in a Tertiary Hospital, North-Central Nigeria","authors":"Abdussemee Abdurrazzaaq, V. Grimah, A. Yakubu","doi":"10.24018/ejmed.2023.5.3.1634","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1634","url":null,"abstract":"Background: Typhoid intestinal perforation is the most common surgical complication and a significant cause of morbidity and mortality in typhoid fever. \u0000Aim: To determine the treatment outcome of patients with typhoid intestinal perforation. \u0000Methods: A single-centre retrospective study involving retrieving case notes of all consecutive patients who had surgeries for peritonitis secondary to typhoid intestinal perforation from October 2016 to September 2017. Data were collected with a designed case report form and analysed. \u0000Results: Sixty-nine patients had surgeries for typhoid intestinal perforation, of which forty-five (65.2%) were males. The median (range) age of the participants was 10(4-44) years. The commonest complications were surgical site infections 49 (71%) and wound dehiscence 17 (24.6%). The median (range) post-operative hospital stay among the survivors was 13 (7 – 50) days. Enterocutaneous fistula and wound dehiscence were responsible for prolonged hospital stay (x2= 30.126, p value< 0.001 and x2= 45.777, p value< 0.001 respectively). The overall mortality rate was 19 (27.5%). Under-five children had the highest mortality rate 5/15 (33.3%). Mortality was found to be more common among females though the association was not statistically significant (p value = 0.052). Mortality was significantly associated with extended surgical procedures (p value= 0.027). \u0000Conclusion: The reported cases of typhoid intestinal perforations at the study centre were high but the mortality rate was comparable to other similar studies in Nigeria. Mortality from typhoid perforation remains high, and the pathology is best prevented","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128518446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-02DOI: 10.24018/ejmed.2023.5.3.1625
Glenn Kristie Wanaditya, I. Putra, M. Aryana, R. Mulyana
Obesity in pregnancy is currently a health problem that is associated with increased maternal and neonatal morbidity. Along with the times and lifestyles that are more modern, the incidence of obesity is also increasing. Clinically, obesity is defined as the condition of having excess adipose tissue. Obesity is related to insulin resistance and chronic inflammation. This makes obesity a risk factor for various non-contagious diseases such as cardiovascular disease, hypertension, diabetes mellitus, and cancer. The health consequences of maternal obesity are based on low-grade, chronic (meta-inflammatory) inflammation that occurs as a result of changes in the immune system and proinflammatory cytokines in maternal obesity and pregnancy. Obesity can have a negative impact on maternal, neonatal and labor outcomes. Several maternal complications that can occur due to obesity (BMI 30-34.9) and morbid obesity (BMI ≥ 35) are hypertension during pregnancy (10.2-12.3%), preeclampsia (3-6.3%), gestational diabetes (6.3-9.5%). Risks that can occur to the fetus, such as the occurrence of macrosomia (15.4-17.2%), preterm birth (4-5.5%) and impaired fetal growth (1-0.8%). Maternal obesity is also associated with an increased risk of neural tube defects (NTD) in babies, as well as a higher risk of abortion (1.70-3.11%). Obesity also has an impact on the delivery process. Mothers with obesity have a higher rate of vaginal operative procedures (8.5-11.1%), labor induction and longer duration of labor. The increase in caesarean section deliveries is caused by the occurrence of complications due to maternal obesity, namely the occurrence of preeclampsia, fetal distress, macrosomia, and induction failure.
{"title":"Obesity in Pregnant Women and Its Impact on Maternal and Neonatal Morbidity","authors":"Glenn Kristie Wanaditya, I. Putra, M. Aryana, R. Mulyana","doi":"10.24018/ejmed.2023.5.3.1625","DOIUrl":"https://doi.org/10.24018/ejmed.2023.5.3.1625","url":null,"abstract":"Obesity in pregnancy is currently a health problem that is associated with increased maternal and neonatal morbidity. Along with the times and lifestyles that are more modern, the incidence of obesity is also increasing. Clinically, obesity is defined as the condition of having excess adipose tissue. Obesity is related to insulin resistance and chronic inflammation. This makes obesity a risk factor for various non-contagious diseases such as cardiovascular disease, hypertension, diabetes mellitus, and cancer. The health consequences of maternal obesity are based on low-grade, chronic (meta-inflammatory) inflammation that occurs as a result of changes in the immune system and proinflammatory cytokines in maternal obesity and pregnancy. Obesity can have a negative impact on maternal, neonatal and labor outcomes. Several maternal complications that can occur due to obesity (BMI 30-34.9) and morbid obesity (BMI ≥ 35) are hypertension during pregnancy (10.2-12.3%), preeclampsia (3-6.3%), gestational diabetes (6.3-9.5%). Risks that can occur to the fetus, such as the occurrence of macrosomia (15.4-17.2%), preterm birth (4-5.5%) and impaired fetal growth (1-0.8%). Maternal obesity is also associated with an increased risk of neural tube defects (NTD) in babies, as well as a higher risk of abortion (1.70-3.11%). Obesity also has an impact on the delivery process. Mothers with obesity have a higher rate of vaginal operative procedures (8.5-11.1%), labor induction and longer duration of labor. The increase in caesarean section deliveries is caused by the occurrence of complications due to maternal obesity, namely the occurrence of preeclampsia, fetal distress, macrosomia, and induction failure.","PeriodicalId":113708,"journal":{"name":"European Journal of Medical and Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122378443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：