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Clinical Features and Biomarkers for Early Prediction of Refractory Mycoplasma Pneumoniae Pneumonia in Children 用于早期预测儿童难治性肺炎支原体肺炎的临床特征和生物标志物
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-05 DOI: 10.1155/2024/9328177
Qin Chen, Tingting Hu, Ling Wu, Lumin Chen
<i>Summary of Background Data</i>.With the increasing incidence and mortality of refractory mycoplasma pneumonia (RMPP), the early diagnosis and treatment of RMPP have attracted more and more attention and have become a major concern in pediatrics. <i>Objective</i>. The study aimed to analyze the clinical characteristics of children with RMPP and to explore the biomarkers for the early prediction of RMPP, thus providing references for the clinical diagnosis and treatment of RMPP in children. <i>Methods</i>. Baseline clinical characteristics, clinical symptoms, physical examination, chest imaging, and laboratory indicators between children with RMPP and general refractory mycoplasma pneumoniae pneumonia (GMPP) were compared. Multiple logistic regression analysis was used to determine independent risk factors for RMPP. ROC curves were adopted to analyze the predictive values of biomarkers. <i>Results</i>. The RMPP group had more severe clinical symptoms and manifestations on imaging (including pleural effusion, pulmonary consolidation, and pulmonary atelectasis), a higher incidence of extrapulmonary complications, and a longer duration of hospital stays. Results of multiple logistic regression analysis showed that serum D-dimer (OR = 8.169, <span><svg height="9.2729pt" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 19.289 9.2729" width="19.289pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"></path></g><g transform="matrix(.013,0,0,-0.013,11.658,0)"></path></g></svg><span></span><span><svg height="9.2729pt" style="vertical-align:-0.6370001pt" version="1.1" viewbox="22.8711838 -8.6359 28.182 9.2729" width="28.182pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.921,0)"></path></g><g transform="matrix(.013,0,0,-0.013,29.161,0)"></path></g><g transform="matrix(.013,0,0,-0.013,32.125,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,38.365,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,44.605,0)"></path></g></svg>),</span></span> C-reactive protein (CRP) (OR = 1.146, <span><svg height="9.2729pt" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 19.289 9.2729" width="19.289pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><use xlink:href="#g113-81"></use></g><g transform="matrix(.013,0,0,-0.013,11.658,0)"><use xlink:href="#g117-91"></use></g></svg><span></span><span><svg height="9.2729pt" style="vertical-align:-0.6370001pt" version="1.1" viewbox="22.8711838 -8.6359 28.182 9.2729" width="28.182pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.921,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,29.161,0)"><use xlink:href=
背景资料摘要:随着难治性支原体肺炎(RMPP)发病率和死亡率的不断上升,RMPP 的早期诊断和治疗已引起越来越多的关注,并已成为儿科领域的一个重要问题。研究目的本研究旨在分析 RMPP 患儿的临床特征,探讨早期预测 RMPP 的生物标志物,从而为儿童 RMPP 的临床诊断和治疗提供参考。研究方法比较RMPP患儿和一般难治性肺炎支原体肺炎(GMPP)患儿的基线临床特征、临床症状、体格检查、胸部影像学检查和实验室指标。采用多元逻辑回归分析确定 RMPP 的独立危险因素。采用ROC曲线分析生物标志物的预测价值。结果RMPP组的临床症状和影像学表现(包括胸腔积液、肺部合并症和肺不张)更严重,肺外并发症的发生率更高,住院时间更长。多元逻辑回归分析结果显示,血清 D-二聚体(OR = 8.169,)、C 反应蛋白(CRP)(OR = 1.146,)和乳酸脱氢酶(LDH)(OR = 1.025,)水平是 RMPP 的独立危险因素。D-二聚体、CRP和LDH血清水平预测RMPP的接收者操作特征曲线下面积(AUROC)分别为0.841、0.870和0.893(),临界值分别为1.47纳克/毫升、39.34毫克/升和379 IU/升。结论血清D-二聚体、CRP和LDH水平与儿童肺炎支原体肺炎的严重程度有关,有可能成为早期预测RMPP的生物标志物,对临床早期诊断和及时干预RMPP患儿具有重要的应用价值。
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引用次数: 0
Prevalence, Risk Factors, and Mortality of Patients Presenting with Moderate and Severe Hyponatremia in Emergency Departments 急诊科中度和重度低钠血症患者的患病率、风险因素和死亡率
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-31 DOI: 10.1155/2023/9946578
Randa Farah, Nisreen Asha, Farah Mezher, Saja Maaitah, Fedaa Abu Al-Samen, Farah Abu Abboud, Salma Ajarmeh
<i>Background</i>. Hyponatremia is among the most common electrolyte disturbances encountered in clinical practice and is associated with a high rate of morbidity and mortality. However, there are very limited data on adult cases presenting to emergency departments with hyponatremia. <i>Objectives</i>. This study aimed to evaluate the frequency, clinical characteristics, and outcomes in hyponatremic patients presenting to emergency departments. <i>Methods</i>. This retrospective study analyzed all patients older than 18 years who visited our institution’s emergency department between October 2018 and October 2019 and has a serum sodium (Na) level <130 mmol/L. <i>Results</i>. Among 24,982 patients who visited the emergency department and had a documented serum sodium level, 284 were included. Patients’ median age was 67.13 ± 14.8 years. Younger patients are less likely to develop severe hyponatremia compared to older patients (adjusted odds ratio (AOR): 0.415; 95% confidence interval (CI): 0.231–0.743; <span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 18.973 11.7782" width="18.973pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"></path></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"></path></g></svg><span></span><span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="22.555183800000002 -8.34882 28.184 11.7782" width="28.184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.605,0)"></path></g><g transform="matrix(.013,0,0,-0.013,28.845,0)"></path></g><g transform="matrix(.013,0,0,-0.013,31.809,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,38.049,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,44.289,0)"></path></g></svg>).</span></span> Asymptomatic hyponatremia and gastrointestinal manifestations were the most common presenting hyponatremia symptoms (33.7% and 24.2%, respectively). Proton pump inhibitor (PPI) use, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACE/ARB) use, and spironolactone use (OR = 2.6 and 3.9, 2.3 with a <span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 18.973 11.7782" width="18.973pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><use xlink:href="#g113-113"></use></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"><use xlink:href="#g117-34"></use></g></svg><span></span><span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="22.555183800000002 -8.34882 21.921 11.7782" width="21.921pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.605,0)"><use xlink:href="#g113-49"></use></g><
背景。低钠血症是临床上最常见的电解质紊乱之一,发病率和死亡率都很高。然而,有关成人低钠血症急诊病例的数据非常有限。研究目的本研究旨在评估急诊科低钠血症患者的发病频率、临床特征和预后。方法。这项回顾性研究分析了2018年10月至2019年10月期间到我院急诊科就诊的所有18岁以上、血清钠(Na)水平为<130 mmol/L的患者。研究结果在 24982 名到急诊科就诊并有血清钠水平记录的患者中,有 284 人被纳入其中。患者的中位年龄为 67.13 ± 14.8 岁。与老年患者相比,年轻患者发生严重低钠血症的几率较低(调整后的几率比(AOR):0.415;95% 置信区间(CI):0.231-0.743;)。无症状性低钠血症和胃肠道表现是最常见的低钠血症症状(分别为 33.7% 和 24.2%)。使用质子泵抑制剂(PPI)、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂(ACE/ARB)和螺内酯(OR = 2.6 和 3.9,2.3,a , 0.03 和 0.05)与严重低钠血症的几率增加有关。重度和中度低钠血症组在发病后 6 个月内的总死亡率没有差异(11.1% 对 16.2%)。结论在急诊科就诊的患者中,中度和重度低钠血症并不少见。中度低钠血症可无症状,但有临床意义。与中度低钠血症相比,老年患者、使用 PPI、使用 ACEi/ARBs 和使用螺内酯与重度低钠血症的风险增加有关。要证实我们的研究结果,还需要对更多的人群进行进一步的前瞻性分析。
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引用次数: 0
Clinical Implications of the Lung Ultrasound Score in Patients after Cardiopulmonary Resuscitation 心肺复苏后患者肺部超声评分的临床意义
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-26 DOI: 10.1155/2023/4951950
Yi-Ling Zhang, Zhou Yang, Jie Cao, Yu-Long Bai, Chun-Yun Fang, Wei Wang
Background. Lung ultrasound score (LUS) is a clinical index used to measure lung injury, but its clinical value in patients after cardiopulmonary resuscitation (CPR) remains relatively unknown. The purpose of this study was to investigate the clinical value of LUS in patients after CPR. Methods. This retrospective study included a total of 34 patients older than 18 years with a nontraumatic cause of in-hospital cardiac arrest, who received standard resuscitation and achieved return of spontaneous circulation (ROSC). All patients underwent bedside lung ultrasound examination within half an hour once ROSC was achieved, and LUSs were calculated. The study included patient death as the endpoint event. Results. Compared with the group with lower LUSs, the patients with higher LUSs had a lower oxygenation index, longer duration of CPR, and lower 72 h survival rate. The initial LUS had good clinical value in predicting the secondary outcomes of CPR (adjusted odds ratio (aOR): 1.353, 95% confidence interval (CI): 1.018–1.797, and  = 0.037) and 72 h survival rate of patients who underwent CPR (aOR: 1.145, 95% CI: 1.014–1.294, and  = 0.029). Conclusions. LUS was shown to be helpful and had a prognostic value in patients after CPR.
背景。肺部超声评分(LUS)是一项用于测量肺损伤的临床指标,但其在心肺复苏(CPR)后患者中的临床价值仍相对未知。本研究旨在探讨 LUS 在心肺复苏术后患者中的临床价值。方法。这项回顾性研究共纳入了 34 名年龄在 18 岁以上、非创伤性原因导致的院内心脏骤停患者,他们都接受了标准复苏并实现了自主循环(ROSC)的恢复。所有患者均在 ROSC 恢复后半小时内接受了床旁肺部超声检查,并计算了 LUS。研究将患者死亡作为终点事件。研究结果与 LUS 值较低的一组相比,LUS 值较高的患者氧合指数较低,心肺复苏时间较长,72 小时存活率较低。初始 LUS 在预测心肺复苏的次要结果(调整后比值比 (aOR):1.353,95% 置信区间 (CI):1.018-1.797,和 = 0.037)和接受心肺复苏患者的 72 小时存活率(aOR:1.145,95% CI:1.014-1.294,和 = 0.029)方面具有良好的临床价值。结论LUS 对心肺复苏后的患者有帮助并具有预后价值。
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引用次数: 0
Retracted: Clinical Value of Pleural Effusion and Serum MMP-3 and CYFRA21-1 Combined with ADA in Differential Diagnosis of Pleural Exudative Effusion. 撤回:胸腔积液、血清MMP-3和CYFRA21-1与ADA结合在胸腔渗出性积液鉴别诊断中的临床价值
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9765351
Emergency Medicine International

[This retracts the article DOI: 10.1155/2022/1615058.].

[本文撤回文章 DOI:10.1155/2022/1615058.]。
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引用次数: 0
Retracted: Analysis of the Effect of Rational Emotional Intervention Combined with Hierarchical Management Mode on Improving the Psychological Stress of Emergency Nurses and Trainee Nurses 撤稿:理性情绪干预结合分层管理模式对改善急诊科护士及实习护士心理压力的效果分析
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 DOI: 10.1155/2023/9874893
Emergency Medicine International
{"title":"Retracted: Analysis of the Effect of Rational Emotional Intervention Combined with Hierarchical Management Mode on Improving the Psychological Stress of Emergency Nurses and Trainee Nurses","authors":"Emergency Medicine International","doi":"10.1155/2023/9874893","DOIUrl":"https://doi.org/10.1155/2023/9874893","url":null,"abstract":"<jats:p />","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"14 7","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retracted: Study on the Changes of Liver and Kidney Function-Related Indicators and Clinical Significance in Patients with OSAHS 撤回:OSAHS患者肝肾功能相关指标变化及临床意义研究
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 DOI: 10.1155/2023/9754073
Emergency Medicine International
{"title":"Retracted: Study on the Changes of Liver and Kidney Function-Related Indicators and Clinical Significance in Patients with OSAHS","authors":"Emergency Medicine International","doi":"10.1155/2023/9754073","DOIUrl":"https://doi.org/10.1155/2023/9754073","url":null,"abstract":"<jats:p />","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"28 6","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138955010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retracted: Study on the Current Status and Influencing Factors of Workplace Violence to Medical Staff in Intensive Care Units 撤回:重症监护室医务人员工作场所暴力现状及影响因素研究
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 DOI: 10.1155/2023/9858795
Emergency Medicine International
{"title":"Retracted: Study on the Current Status and Influencing Factors of Workplace Violence to Medical Staff in Intensive Care Units","authors":"Emergency Medicine International","doi":"10.1155/2023/9858795","DOIUrl":"https://doi.org/10.1155/2023/9858795","url":null,"abstract":"<jats:p />","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"29 38","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138955152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retracted: Comparison of the Effects of Hysteroscopic Cold Broad Sword Play Combined with Estrogen and Progestin Sequential Therapy and Drospirenone and Ethinylestradiol Tablets in Patients with Severe Intrauterine Adhesion 撤回:宫腔镜冷阔剑法联合雌激素和孕激素序贯疗法与屈螺酮和炔雌醇片剂对严重宫内粘连患者的效果比较
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 DOI: 10.1155/2023/9805463
Emergency Medicine International
{"title":"Retracted: Comparison of the Effects of Hysteroscopic Cold Broad Sword Play Combined with Estrogen and Progestin Sequential Therapy and Drospirenone and Ethinylestradiol Tablets in Patients with Severe Intrauterine Adhesion","authors":"Emergency Medicine International","doi":"10.1155/2023/9805463","DOIUrl":"https://doi.org/10.1155/2023/9805463","url":null,"abstract":"<jats:p />","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"37 18","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138955654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retracted: Clinical Effect and Aesthetic Evaluation of Minimally Invasive Implant Therapy 撤回:微创种植治疗的临床效果和美学评估
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 DOI: 10.1155/2023/9756841
Emergency Medicine International
{"title":"Retracted: Clinical Effect and Aesthetic Evaluation of Minimally Invasive Implant Therapy","authors":"Emergency Medicine International","doi":"10.1155/2023/9756841","DOIUrl":"https://doi.org/10.1155/2023/9756841","url":null,"abstract":"<jats:p />","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"26 9","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138955094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retracted: Effect of Compound Polyethylene Glycol Electrolyte Powder on the Quality of Gastrobowel Preparation before Enteroscopy Intervention. 撤回:复方聚乙二醇电解质粉对肠镜检查前胃肠准备质量的影响。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-20 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9810628
Emergency Medicine International

[This retracts the article DOI: 10.1155/2022/9895499.].

[此文撤消了文章 DOI:10.1155/2022/9895499.]。
{"title":"Retracted: Effect of Compound Polyethylene Glycol Electrolyte Powder on the Quality of Gastrobowel Preparation before Enteroscopy Intervention.","authors":"Emergency Medicine International","doi":"10.1155/2023/9810628","DOIUrl":"10.1155/2023/9810628","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/9895499.].</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2023 ","pages":"9810628"},"PeriodicalIF":1.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10752727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139048443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Emergency Medicine International
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