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Chest CT as a diagnostic tool for COVID-19 in resource-limited Countries : Diagnostic accuracy of chest CT for COVID-19 pneumonia in a resource-limited Gaza cohort: a retrospective study of 252 patients. 在资源有限的国家,胸部CT作为COVID-19的诊断工具:在资源有限的加沙队列中,胸部CT对COVID-19肺炎的诊断准确性:一项252例患者的回顾性研究。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-09-17 DOI: 10.1007/s10140-025-02388-5
Deniz Esin Tekcan Sanli, Ahmet Necati Sanli
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引用次数: 0
The sonographic Murphy sign: does analgesia matter? 超声墨菲征:镇痛重要吗?
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-09-24 DOI: 10.1007/s10140-025-02387-6
Elianna L Goldstein, Karina R Marcelo, William R Harjes, Jonathan R Wood, Yang-En Kao

Purpose: Controversy exists regarding analgesia premedication prior to right upper quadrant ultrasound (RUQUS) in the setting of abdominal pain when evaluating for acute cholecystitis (AC). The purpose of this study was to examine the effect of opioid and non-opioid analgesia (OA and NOA, respectively) on the sonographic Murphy sign (maximal tenderness when an ultrasound transducer probe is pressed over the visualized gallbladder) and the radiologic accuracy of diagnosing AC.

Methods: A retrospective cohort chart review analyzed 686 adult patients in two groups and the effect on diagnosis of AC in the emergency department: those who received OA versus control and another group comparing NOA versus control.

Results: OA resulted in an increased rate of indeterminate sonographic Murphy sign and diagnoses in the treatment group compared to control (7.9% vs. 3.0%, respectively). This resulted in 24 cases of radiology-missed AC. However, there was no statistically significant difference in false-negative AC diagnosis between the NOA group compared to control (4.6% vs. 3.7%, respectively). Patients receiving OA within 30 minutes of their RUQUS examination were more likely to be given a false-negative diagnosis compared to control (8.5% vs 3.0%, respectively). Even morphine-equivalent doses <4mg were associated with increased false-negatives compared to control (8.0% vs 3.0%, respectively).

Conclusions: Clinicians should consider delaying OA until after the RUQUS or consider delaying the study at least 30 minutes after the administration of OA due to increased risk of false-negative results. Additionally, our results suggest that administration of NOA is a viable alternative analgesic option for many patients without sacrificing diagnostic accuracy.

目的:在评估急性胆囊炎(AC)时,在腹痛的情况下,右上腹超声(RUQUS)前是否进行镇痛治疗存在争议。本研究的目的是探讨阿片类药物和非阿片类药物镇痛(分别为OA和NOA)对超声墨菲征(超声换能器探头压在可见胆囊上时最大压痛)的影响以及诊断AC的放射学准确性。方法:回顾性队列分析两组686例成年患者及其对急诊科AC诊断的影响。一组接受OA与对照组,另一组接受NOA与对照组。结果:与对照组相比,治疗组OA导致不确定超声墨菲征象和诊断率增加(分别为7.9%和3.0%)。这导致24例放射学漏诊AC。然而,与对照组相比,NOA组之间AC假阴性诊断无统计学差异(分别为4.6%和3.7%)。与对照组相比,在RUQUS检查后30分钟内接受OA的患者更有可能得到假阴性诊断(分别为8.5%和3.0%)。结论:临床医生应考虑将OA延迟到RUQUS之后,或考虑将OA给药后至少30分钟延迟研究,因为假阴性结果的风险增加。此外,我们的研究结果表明,对许多患者来说,在不牺牲诊断准确性的情况下,给予NOA是一种可行的替代镇痛选择。
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引用次数: 0
Avulsion fracture of the posterior calcaneal tuberosity: anatomy, injury patterns, and an approach to management. 跟骨后结节撕脱骨折:解剖、损伤模式及处理方法。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-10-15 DOI: 10.1007/s10140-025-02402-w
Eric A White, Alexander J White, Matthew R Skalski, MeNore G Lake, Michael K Chiu, Dani Sarohia, Nicholas A Lewis, Dakshesh B Patel

Calcaneal tuberosity avulsion fractures are often treated differently depending on several factors, including imaging diagnosis and classification. Timely identification of imaging findings, accurate interpretation, and effective communication can help avert serious clinical complications, including the necessity for soft tissue coverage and amputation. This article reviews the anatomy of the calcaneus, as well as the clinical and imaging findings of calcaneal tuberosity fractures. Imaging interpretation and clinical management of these fractures are discussed.

跟骨结节撕脱性骨折的治疗通常取决于几个因素,包括影像学诊断和分类。及时识别影像学表现、准确解读和有效沟通有助于避免严重的临床并发症,包括软组织覆盖和截肢的必要性。本文综述了跟骨的解剖,以及跟骨结节骨折的临床和影像学表现。本文讨论了这些骨折的影像学解释和临床处理。
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引用次数: 0
Early Clues, critical outcomes: a pictorial review of subtle intracranial pathologies on non-contrast head CT. 早期线索,关键结果:非对比头部CT上细微颅内病变的图像回顾。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-10-23 DOI: 10.1007/s10140-025-02408-4
Fırat Atak, Ömer Önder, Yasin Yaraşır, Mehmet Ruhi Onur

Non-contrast head CT (NCHCT) remains the first-line imaging modality for acute neurologic presentations, but subtle yet critical pathologies can be missed due to its inherent technical limitations. This pictorial review provides a systematic, anatomy-based framework covering all major anatomical compartments visible on emergency NCHCT, serving as a practical educational guide for radiology residents and emergency physicians. The review summarizes key imaging patterns, relevant clinical contexts, and technical optimization methods that aid in detecting subtle intracranial pathologies across anatomical regions. The anatomical areas covered are: Intra-axial: Cerebral hemispheres, deep gray nuclei, brainstem, cerebellum, and the periventricular region. Extra-axial: Subdural, subarachnoid, and meningeal abnormalities, including cranial nerve pathologies. Vascular structures, sellar/parasellar regions, osseous structures, and extracranial soft tissues. A disciplined, systematic interpretation that extends beyond the brain parenchyma to all visible structures, combined with technical optimization and clinical correlation, is crucial for minimizing diagnostic errors and improving patient outcomes.

非对比头部CT (NCHCT)仍然是急性神经系统表现的一线成像方式,但由于其固有的技术限制,可能会错过微妙但关键的病理。这篇图片综述提供了一个系统的、基于解剖学的框架,涵盖了急诊NCHCT上可见的所有主要解剖区,作为放射科住院医生和急诊医生的实用教育指南。这篇综述总结了关键的成像模式、相关的临床背景和技术优化方法,这些方法有助于检测跨解剖区域的细微颅内病变。解剖区域包括:轴内:大脑半球、深灰色核、脑干、小脑和脑室周围区域。轴外:硬膜下、蛛网膜下和脑膜异常,包括颅神经病变。血管结构、鞍区/鞍旁区、骨结构和颅外软组织。一个从脑实质延伸到所有可见结构的有纪律的、系统的解释,结合技术优化和临床相关性,对于最大限度地减少诊断错误和改善患者预后至关重要。
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引用次数: 0
Prognostic validation of a simplified chest CT severity score in COVID-19 patients from resource-limited Gaza. 资源有限的加沙地区COVID-19患者简化胸部CT严重程度评分的预后验证
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-10-18 DOI: 10.1007/s10140-025-02393-8
Husam H Mansour, Noor Khairiah A Karim, Noor Diyana Osman, Rohayu Hami, Yasser S Alajerami

Purpose: To validate the Simplified Chest CT Severity Score (SCCTSS) for prognostic stratification of COVID-19 pneumonia in a resource-limited Gaza cohort and compare its diagnostic accuracy and interobserver reliability against the established Chest CT Score (CCTS).

Materials and methods: In this retrospective cohort study, 360 adult patients with RT-PCR-confirmed COVID-19 underwent non-contrast chest CT within 72 h of admission (September 2020-June 2022). SCCTSS assessed three parameters, opacity type, extent, and distribution, with scores ranging from 0 to 7 and classified into no involvement (0), mild (3), moderate (4-5), and severe (6-7) disease. CCTS scores ranged from 0 to 25 and were categorized as no involvement (0), mild (1-8), moderate (9-16), and severe (17-25). Interobserver agreement was measured by Cohen's kappa. Diagnostic accuracy for mortality prediction was evaluated via sensitivity, specificity, ROC curves, and Kaplan-Meier survival analyses.

Results: SCCTSS demonstrated almost perfect interobserver reliability (κ = 0.883), comparable to CCTS (κ = 0.870). Mortality was significantly associated with higher SCCTSS categories; 58.5% of non-survivors had severe scores (6-7), compared to 3.7% of survivors (p < 0.001). At the optimal cutoff (≥ 3.5), SCCTSS sensitivity was 93.2%, specificity 90.1%, with AUC 0.933. CCTS (cutoff ≥ 8.5) showed 89.8% sensitivity, 93.4% specificity, and AUC 0.948. Kaplan-Meier analysis confirmed significantly reduced 30-day survival in patients with scores above these thresholds (p < 0.001).

Conclusions: SCCTSS is a simple, reproducible, and effective CT scoring tool for COVID-19 prognostication, suitable for rapid risk stratification in resource-limited environments.

目的:在资源有限的加沙队列中验证简化胸部CT严重程度评分(SCCTSS)对COVID-19肺炎的预后分层,并将其诊断准确性和观察者间可靠性与既定胸部CT评分(CCTS)进行比较。材料和方法:在这项回顾性队列研究中,360名成年rt - pcr确诊的COVID-19患者在入院后72小时内(2020年9月- 2022年6月)进行了胸部非对比CT检查。SCCTSS评估了三个参数:不透明类型、程度和分布,评分范围从0到7,分为无受累(0)、轻度(3)、中度(4-5)和重度(6-7)。CCTS评分范围从0到25,分为无受累(0)、轻度(1-8)、中度(9-16)和重度(17-25)。观察者之间的一致是由科恩的kappa来衡量的。通过敏感性、特异性、ROC曲线和Kaplan-Meier生存分析来评估死亡率预测的诊断准确性。结果:SCCTSS表现出近乎完美的观察者间信度(κ = 0.883),与CCTS相当(κ = 0.870)。死亡率与较高的SCCTSS类别显著相关;58.5%的非幸存者评分为重度(6-7分),而幸存者的这一比例为3.7% (p)。结论:SCCTSS是一种简单、可重复且有效的CT评分工具,适用于资源有限环境下的快速风险分层。
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引用次数: 0
Imaging requests for acute abdominal pain in the emergency department: a retrospective cross-sectional study. 急诊科急性腹痛影像学要求:一项回顾性横断面研究。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-09-17 DOI: 10.1007/s10140-025-02385-8
Esteban Vasquez, Andrea Torres, Belén Báez, Lía Rodríguez, Diego Cienfuegos, Marcelo Castro

Purpose: To evaluate whether the appropriateness of imaging requests (AIR) for acute abdominal pain (AAP) in two private hospitals in Santiago (2023) was associated with higher diagnostic yield, and to explore predictors through a multivariable model.

Methods: A retrospective cross-sectional study included patients aged ≥ 15 years presenting with AAP who underwent US, CT, or MRI. AIR was classified according to the ACR Appropriateness Criteria, and radiology reports were categorized as confirmatory or normal. A multivariable logistic regression model, incorporating interactions between AIR, imaging modality, and age, was applied to identify predictors of diagnostic yield.

Results: A total of 189 imaging studies were analyzed (75 US, 62 CT, 52 MRI). Overall, 57.7% of requests were appropriate. Confirmatory findings occurred in 66.1% of cases, significantly more frequent in appropriate requests (84.4%) than in inappropriate ones (41.3%; p < 0.01). Inappropriateness reduced diagnostic yield from 78.3% to 17.4% in US and from 91.5% to 25.9% in CT, with no significant difference for MRI (86% vs. 81.3%). Older age was independently associated with higher probabilities of confirmatory findings. Epigastric pain and acute gastroenteritis were disproportionately linked to overuse, while hepatobiliary conditions showed predominantly appropriate use. The model demonstrated high discriminatory performance (AUC = 0.88).

Conclusion: Adherence to ACR criteria was strongly associated with improved diagnostic yield in AAP, particularly for CT and US. Age and local epidemiology, including high biliary disease prevalence, influenced modality performance. These findings support context-sensitive decision-support tools and prospective studies to refine imaging strategies and enhance patient safety in emergency care.

目的:评估圣地亚哥两家私立医院(2023年)急性腹痛(AAP)的影像学要求(AIR)的适当性是否与更高的诊断率相关,并通过多变量模型探讨预测因素。方法:一项回顾性横断面研究包括年龄≥15岁的AAP患者,他们接受了US、CT或MRI检查。AIR根据ACR适宜性标准进行分类,放射学报告分为确诊或正常。采用多变量逻辑回归模型,结合空气、成像方式和年龄之间的相互作用,确定诊断率的预测因子。结果:共分析了189份影像学研究(75份US, 62份CT, 52份MRI)。总体而言,57.7%的请求是适当的。确诊性发现在66.1%的病例中出现,在适当的请求中出现的频率(84.4%)明显高于不适当的请求(41.3%);p结论:遵守ACR标准与AAP诊断率的提高密切相关,尤其是CT和US。年龄和当地流行病学,包括高胆道疾病患病率,影响了模态的表现。这些发现支持上下文敏感的决策支持工具和前瞻性研究,以完善成像策略并提高急诊护理中的患者安全。
{"title":"Imaging requests for acute abdominal pain in the emergency department: a retrospective cross-sectional study.","authors":"Esteban Vasquez, Andrea Torres, Belén Báez, Lía Rodríguez, Diego Cienfuegos, Marcelo Castro","doi":"10.1007/s10140-025-02385-8","DOIUrl":"10.1007/s10140-025-02385-8","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate whether the appropriateness of imaging requests (AIR) for acute abdominal pain (AAP) in two private hospitals in Santiago (2023) was associated with higher diagnostic yield, and to explore predictors through a multivariable model.</p><p><strong>Methods: </strong>A retrospective cross-sectional study included patients aged ≥ 15 years presenting with AAP who underwent US, CT, or MRI. AIR was classified according to the ACR Appropriateness Criteria, and radiology reports were categorized as confirmatory or normal. A multivariable logistic regression model, incorporating interactions between AIR, imaging modality, and age, was applied to identify predictors of diagnostic yield.</p><p><strong>Results: </strong>A total of 189 imaging studies were analyzed (75 US, 62 CT, 52 MRI). Overall, 57.7% of requests were appropriate. Confirmatory findings occurred in 66.1% of cases, significantly more frequent in appropriate requests (84.4%) than in inappropriate ones (41.3%; p < 0.01). Inappropriateness reduced diagnostic yield from 78.3% to 17.4% in US and from 91.5% to 25.9% in CT, with no significant difference for MRI (86% vs. 81.3%). Older age was independently associated with higher probabilities of confirmatory findings. Epigastric pain and acute gastroenteritis were disproportionately linked to overuse, while hepatobiliary conditions showed predominantly appropriate use. The model demonstrated high discriminatory performance (AUC = 0.88).</p><p><strong>Conclusion: </strong>Adherence to ACR criteria was strongly associated with improved diagnostic yield in AAP, particularly for CT and US. Age and local epidemiology, including high biliary disease prevalence, influenced modality performance. These findings support context-sensitive decision-support tools and prospective studies to refine imaging strategies and enhance patient safety in emergency care.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"819-828"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: chest CT as a diagnostic tool for COVID-19 in resource-limited countries. 评论:在资源有限的国家,胸部CT作为COVID-19的诊断工具。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-09-25 DOI: 10.1007/s10140-025-02394-7
Husam H Mansour, Noor Khairiah A Karim, Noor Diyana Osman, Rohayu Hami, Yasser S Alajerami
{"title":"Commentary: chest CT as a diagnostic tool for COVID-19 in resource-limited countries.","authors":"Husam H Mansour, Noor Khairiah A Karim, Noor Diyana Osman, Rohayu Hami, Yasser S Alajerami","doi":"10.1007/s10140-025-02394-7","DOIUrl":"10.1007/s10140-025-02394-7","url":null,"abstract":"","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"1023-1024"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resolution of traumatic adrenal hemorrhage on CT: impact of follow-up timing and initial hematoma size. 外伤性肾上腺出血的CT诊断:随访时间和初始血肿大小的影响。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-09-16 DOI: 10.1007/s10140-025-02396-5
Harry Yip, Maryam Shekarfaroush, Demi Markakis, Humza Tufail, Adil Zia, Jan Gerstenmaier, Bruno Di Muzio

Purpose: Traumatic adrenal gland hemorrhage (TAH) is an uncommon injury which can be managed conservatively in most cases. There are limited studies assessing the interval follow-up and resolution of conservatively managed TAH. The aim of our study was to evaluate the relationship between resolution of TAH, follow-up imaging interval and initial hematoma size. A key objective was to assess the incidence of underlying adrenal masses that may mimic or contribute to hemorrhage.

Methods: Single centre retrospective cross-sectional study of all trauma patients with radiologically reported adrenal hemorrhage from January 1, 2009 to January 1, 2025. Patients were identified through radiology database search, with demographic, imaging and hematoma data collected to analyse associations between resolution, follow-up timing and initial hematoma size.

Results: Of the 246 patients identified, 125 (51%) underwent at least 1 follow-up CT. The first follow-up occurred at a mean interval of 66.9 days; At this time, 60 patients (48%) showed complete resolution, 53 (42%) showed partial resolution and 12 (10%) demonstrated persistent hemorrhage. An underlying adrenal lesion was identified in 1% of patients. There were statistically significant associations between follow-up imaging time interval and hematoma resolution (p = 0.0025), and between the initial hematoma size and the resolution outcome (p < 0.000001).

Conclusion: Complete resolution of TAH occurred more frequently in patients with follow-up imaging at ≥ 30 days post injury. Hematomas measuring < 27 mm on initial imaging were more likely to resolve completely. Underlying adrenal lesions were rare. These findings may assist trauma centres in refining follow-up imaging strategies for conservatively managed TAH.

目的:外伤性肾上腺出血(TAH)是一种罕见的损伤,在大多数情况下可以保守治疗。有有限的研究评估间隔随访和解决保守管理TAH。我们的研究目的是评估TAH分辨率、随访影像间隔和初始血肿大小之间的关系。一个关键的目的是评估潜在的肾上腺肿块的发生率,可能模拟或促成出血。方法:对2009年1月1日至2025年1月1日所有经放射学报告肾上腺出血的创伤患者进行单中心回顾性横断面研究。通过放射学数据库搜索确定患者,收集人口统计学、影像学和血肿数据,分析消退、随访时间和初始血肿大小之间的关系。结果:在确定的246例患者中,125例(51%)接受了至少1次随访CT。第一次随访平均间隔66.9天;此时,60例(48%)患者完全消退,53例(42%)患者部分消退,12例(10%)患者持续出血。在1%的患者中发现潜在的肾上腺病变。随访时间间隔与血肿消退(p = 0.0025)、初始血肿大小与消退结果(p)之间存在统计学意义的相关性(p)。结论:损伤后≥30天随访影像学患者TAH完全消退的发生率更高。血肿测量
{"title":"Resolution of traumatic adrenal hemorrhage on CT: impact of follow-up timing and initial hematoma size.","authors":"Harry Yip, Maryam Shekarfaroush, Demi Markakis, Humza Tufail, Adil Zia, Jan Gerstenmaier, Bruno Di Muzio","doi":"10.1007/s10140-025-02396-5","DOIUrl":"10.1007/s10140-025-02396-5","url":null,"abstract":"<p><strong>Purpose: </strong>Traumatic adrenal gland hemorrhage (TAH) is an uncommon injury which can be managed conservatively in most cases. There are limited studies assessing the interval follow-up and resolution of conservatively managed TAH. The aim of our study was to evaluate the relationship between resolution of TAH, follow-up imaging interval and initial hematoma size. A key objective was to assess the incidence of underlying adrenal masses that may mimic or contribute to hemorrhage.</p><p><strong>Methods: </strong>Single centre retrospective cross-sectional study of all trauma patients with radiologically reported adrenal hemorrhage from January 1, 2009 to January 1, 2025. Patients were identified through radiology database search, with demographic, imaging and hematoma data collected to analyse associations between resolution, follow-up timing and initial hematoma size.</p><p><strong>Results: </strong>Of the 246 patients identified, 125 (51%) underwent at least 1 follow-up CT. The first follow-up occurred at a mean interval of 66.9 days; At this time, 60 patients (48%) showed complete resolution, 53 (42%) showed partial resolution and 12 (10%) demonstrated persistent hemorrhage. An underlying adrenal lesion was identified in 1% of patients. There were statistically significant associations between follow-up imaging time interval and hematoma resolution (p = 0.0025), and between the initial hematoma size and the resolution outcome (p < 0.000001).</p><p><strong>Conclusion: </strong>Complete resolution of TAH occurred more frequently in patients with follow-up imaging at ≥ 30 days post injury. Hematomas measuring < 27 mm on initial imaging were more likely to resolve completely. Underlying adrenal lesions were rare. These findings may assist trauma centres in refining follow-up imaging strategies for conservatively managed TAH.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"861-866"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for misdiagnosis of interstitial ectopic pregnancy. 间质性异位妊娠误诊的危险因素。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-10-07 DOI: 10.1007/s10140-025-02391-w
Christana O Ajewole, Batsheva R Rubin, Gabrielle H Cherfane, Joseph A Politch, Ann Doherty, Neha Khemani, Andrew Barakat, Christina LeBedis, Alexis K Gadson, Yeon Woo Lee, Justina J Wang, Wendy Kuohung

Purpose: To identify factors contributing to misdiagnosis of interstitial ectopic pregnancy (IEP).

Methods: Retrospective chart review identified patients who presented to Boston Medical Center with suspected and/or true IEP from January 1, 2012 to April 30, 2019. Final diagnoses identified two IEP diagnosis groups: correct initial diagnosis and incorrect initial diagnosis. Data collected included age, gravidity, parity, body mass index (BMI), estimated gestational age, anatomic anomalies of the reproductive tract, smoking status, and history of pelvic surgery, sexually transmitted infections, pelvic inflammatory disease, or adnexal lesions. Continuous variables were analyzed using analysis of covariance and unpaired t-tests. Fisher's exact tests were used for discrete variables.

Results: Of 53 patients with suspected and/or true IEP, 15 (28%) were correctly diagnosed at initial presentation while 38 (72%) were initially incorrectly diagnosed. Patient age was significantly associated with diagnostic group (p = 0.04). Patients in the correctly diagnosed group (Mean ± SD = 35.1 ± 4.2) were significantly older than those incorrectly diagnosed (Mean ± SD = 30.4 ± 4.2) when controlled for gravidity. In univariate analysis, gravidity was associated with diagnostic group, but this association was not significant when controlled for age. Parity demonstrated a similar trend as gravidity but also did not reach significance. Other variables analyzed were not significantly associated with accuracy of initial diagnosis.

Conclusion: Younger women are more likely to have an incorrect initial diagnosis of IEP at presentation to care. Anecdotally, higher tolerance of invasive imaging procedures by older patients with reproductive experience may result in increased accuracy of transvaginal ultrasound examination.

目的:探讨间质性异位妊娠(IEP)的误诊因素。方法:回顾性分析2012年1月1日至2019年4月30日在波士顿医疗中心就诊的疑似和/或真实IEP患者。最终诊断分为两个IEP诊断组:初始诊断正确和初始诊断错误。收集的数据包括年龄、妊娠、胎次、体重指数(BMI)、估计胎龄、生殖道解剖异常、吸烟状况、盆腔手术史、性传播感染、盆腔炎或附件病变。采用协方差分析和非配对t检验对连续变量进行分析。费雪精确检验用于离散变量。结果:在53例疑似和/或真IEP患者中,15例(28%)在初次就诊时被正确诊断,38例(72%)最初被错误诊断。患者年龄与诊断组有显著相关性(p = 0.04)。在控制妊娠情况下,正确诊断组(Mean±SD = 35.1±4.2)明显大于错误诊断组(Mean±SD = 30.4±4.2)。在单变量分析中,体重与诊断组相关,但在控制年龄时,这种关联不显著。宇称表现出与引力相似的趋势,但也没有达到显著性。分析的其他变量与初始诊断的准确性没有显著相关。结论:年轻女性在就诊时更容易有不正确的IEP初步诊断。有趣的是,有生育经验的老年患者对侵入性成像程序的耐受性更高,可能导致经阴道超声检查的准确性提高。
{"title":"Risk factors for misdiagnosis of interstitial ectopic pregnancy.","authors":"Christana O Ajewole, Batsheva R Rubin, Gabrielle H Cherfane, Joseph A Politch, Ann Doherty, Neha Khemani, Andrew Barakat, Christina LeBedis, Alexis K Gadson, Yeon Woo Lee, Justina J Wang, Wendy Kuohung","doi":"10.1007/s10140-025-02391-w","DOIUrl":"10.1007/s10140-025-02391-w","url":null,"abstract":"<p><strong>Purpose: </strong>To identify factors contributing to misdiagnosis of interstitial ectopic pregnancy (IEP).</p><p><strong>Methods: </strong>Retrospective chart review identified patients who presented to Boston Medical Center with suspected and/or true IEP from January 1, 2012 to April 30, 2019. Final diagnoses identified two IEP diagnosis groups: correct initial diagnosis and incorrect initial diagnosis. Data collected included age, gravidity, parity, body mass index (BMI), estimated gestational age, anatomic anomalies of the reproductive tract, smoking status, and history of pelvic surgery, sexually transmitted infections, pelvic inflammatory disease, or adnexal lesions. Continuous variables were analyzed using analysis of covariance and unpaired t-tests. Fisher's exact tests were used for discrete variables.</p><p><strong>Results: </strong>Of 53 patients with suspected and/or true IEP, 15 (28%) were correctly diagnosed at initial presentation while 38 (72%) were initially incorrectly diagnosed. Patient age was significantly associated with diagnostic group (p = 0.04). Patients in the correctly diagnosed group (Mean ± SD = 35.1 ± 4.2) were significantly older than those incorrectly diagnosed (Mean ± SD = 30.4 ± 4.2) when controlled for gravidity. In univariate analysis, gravidity was associated with diagnostic group, but this association was not significant when controlled for age. Parity demonstrated a similar trend as gravidity but also did not reach significance. Other variables analyzed were not significantly associated with accuracy of initial diagnosis.</p><p><strong>Conclusion: </strong>Younger women are more likely to have an incorrect initial diagnosis of IEP at presentation to care. Anecdotally, higher tolerance of invasive imaging procedures by older patients with reproductive experience may result in increased accuracy of transvaginal ultrasound examination.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"841-848"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Setting the benchmark : morocco's first local diagnostic reference levels by clinical indication for pediatric computed tomography across all protocols. 设定基准:摩洛哥首个根据儿科计算机断层扫描临床指征在所有方案中的本地诊断参考水平。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-11-06 DOI: 10.1007/s10140-025-02409-3
H Sekkat, A Khallouqi, A Halimi, Y Madkouri, O El Rhazouani

Purpose: Optimizing radiation protection in pediatric computed tomography (CT) requires diagnostic reference levels (DRLs) adapted to local practice and clinical indication. This study establishes the first Moroccan pediatric CT DRLs stratified by anatomical protocol and diagnostic purpose.

Methods: A descriptive-analytical study was conducted at a single center including 224 children (≤ 15 years) who underwent CT examinations across four main protocols: head, thorax, abdomino-pelvic and thoraco-abdomino-pelvic (TAP). Dosimetric indices (CTDIvol, DLP) and effective doses (E) were analyzed per ICRP recommendations, and DRLs were derived from the 75th percentile of patient-level dose data by clinical indication.

Results: Head CT was the most frequent (54%), dominated by trauma (63.6%) with optimized exposure (median CTDIvol 21.5 mGy; E 3.1 mSv). Structural pathologies showed lower doses (E 2.2 mSv), while infectious cases reached the highest (E 7.2 mSv) due to extended protocols. Thoracic CT exhibited variability, with cardiovascular/malformative cases showing the highest exposures (E 5.8 mSv) and functional respiratory cases the lowest (E 4.0 mSv). Abdomino-pelvic CT delivered the highest doses in tumoral imaging (E 23.6 mSv) and TAP protocols showed comparable DRLs for tumoral and traumatic cases (~ 15-16 mSv).

Conclusion: Clinical indication significantly influences pediatric CT dose, with up to five-fold variation across subgroups. The DRLs established here provide the first national benchmarks for Morocco, supporting protocol optimization, radioprotection policy development and ALARA-compliant pediatric imaging practice.

目的:优化儿童计算机断层扫描(CT)的辐射防护,需要适应当地实践和临床适应症的诊断参考水平(drl)。本研究建立了第一个摩洛哥儿童CT drl,按解剖方案和诊断目的分层。方法:在单一中心进行描述性分析研究,包括224名儿童(≤15岁),他们接受了四个主要方案的CT检查:头部,胸部,腹部-骨盆和胸腹-骨盆(TAP)。根据ICRP建议分析剂量学指标(CTDIvol, DLP)和有效剂量(E), drl根据临床指征从患者水平剂量数据的第75百分位数得出。结果:头部CT最常见(54%),以创伤为主(63.6%),优化暴露(中位CTDIvol 21.5 mGy; E 3.1 mSv)。结构病理学显示较低剂量(e2.2 mSv),而感染性病例由于延长治疗方案而达到最高剂量(e7.2 mSv)。胸部CT表现出变异性,心血管/畸形病例暴露量最高(e5.8 mSv),呼吸功能病例暴露量最低(e4.0 mSv)。腹部-骨盆CT在肿瘤成像中提供了最高剂量(23.6 mSv), TAP方案在肿瘤和创伤病例中显示了相当的drl (~ 15-16 mSv)。结论:临床指征显著影响儿童CT剂量,亚组间差异可达5倍。这里建立的drl为摩洛哥提供了第一个国家基准,支持方案优化、放射防护政策制定和符合alara标准的儿科成像实践。
{"title":"Setting the benchmark : morocco's first local diagnostic reference levels by clinical indication for pediatric computed tomography across all protocols.","authors":"H Sekkat, A Khallouqi, A Halimi, Y Madkouri, O El Rhazouani","doi":"10.1007/s10140-025-02409-3","DOIUrl":"10.1007/s10140-025-02409-3","url":null,"abstract":"<p><strong>Purpose: </strong>Optimizing radiation protection in pediatric computed tomography (CT) requires diagnostic reference levels (DRLs) adapted to local practice and clinical indication. This study establishes the first Moroccan pediatric CT DRLs stratified by anatomical protocol and diagnostic purpose.</p><p><strong>Methods: </strong>A descriptive-analytical study was conducted at a single center including 224 children (≤ 15 years) who underwent CT examinations across four main protocols: head, thorax, abdomino-pelvic and thoraco-abdomino-pelvic (TAP). Dosimetric indices (CTDI<sub>vol</sub>, DLP) and effective doses (E) were analyzed per ICRP recommendations, and DRLs were derived from the 75th percentile of patient-level dose data by clinical indication.</p><p><strong>Results: </strong>Head CT was the most frequent (54%), dominated by trauma (63.6%) with optimized exposure (median CTDI<sub>vol</sub> 21.5 mGy; E 3.1 mSv). Structural pathologies showed lower doses (E 2.2 mSv), while infectious cases reached the highest (E 7.2 mSv) due to extended protocols. Thoracic CT exhibited variability, with cardiovascular/malformative cases showing the highest exposures (E 5.8 mSv) and functional respiratory cases the lowest (E 4.0 mSv). Abdomino-pelvic CT delivered the highest doses in tumoral imaging (E 23.6 mSv) and TAP protocols showed comparable DRLs for tumoral and traumatic cases (~ 15-16 mSv).</p><p><strong>Conclusion: </strong>Clinical indication significantly influences pediatric CT dose, with up to five-fold variation across subgroups. The DRLs established here provide the first national benchmarks for Morocco, supporting protocol optimization, radioprotection policy development and ALARA-compliant pediatric imaging practice.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"849-860"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145451311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Emergency Radiology
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