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Probability of new falls and factors associated with them in aged patients treated in emergency departments after falling: data from the FALL-ER registry. 跌倒后在急诊科治疗的老年患者发生新跌倒的概率及其相关因素:来自FALL-ER登记的数据
Ana García-Martínez, Adriana Gil-Rodrigo, Arrate Placer, Xavier Alemany, Sira Aguiló, Victoria Torres-Machado, Javier Jacob, Pablo Herrero, Pere Llorens, Francisco Javier Martín-Sánchez, Òscar Miró

Objectives: To identify characteristics associated with a new fall in a patient who received emergency department care after an accidental fall and to develop a risk model to predict repeated falls.

Material and methods: The FALL-ER registry included accidental falls in patients over the age of 65 years treated in 5 Spanish emergency departments. Independent variables analyzed were patient characteristics at baseline, fall characteristics, immediate consequences, and functional status on discharge. Patients were followed with telephone interviews for 6 months to record the occurrence of new falls. Multivariate regression analysis was used to identify variables associated with falling again and to develop a risk model. We identified 3 levels of risk for new falls (low, intermediate, and high).

Results: A total of 1313 patients were studied; 147 patients (11.2%) reported having another fall. Variables associated with risk of falling again were having had a fall in the 12 months before the index fall, neurological disease, anemia, use of non-opioid analgesics, falling at home, falling at night, head injury on falling, and need for help when rising from a chair. The probability of falling again was 3.5%, 10.5%, and 23.3%, respectively, in patients at low, intermediate, and high risk. The model's ability to discriminate was moderate: the area under the receiver operating characteristic curve was 0.688 (95% CI, 0.640-0.736).

Conclusion: One in 9 older adults treated in an emergency department for an accidental fall will fall again within 6 months. It is possible to identify patients at higher risk for whom preventive measures should be implemented.

目的:确定意外跌倒后接受急诊科护理的患者新跌倒的相关特征,并建立预测重复跌倒的风险模型。材料和方法:FALL-ER登记包括在西班牙5个急诊科治疗的65岁以上患者的意外跌倒。分析的独立变量包括基线时的患者特征、跌倒特征、即时后果和出院时的功能状态。通过电话随访患者6个月,记录新跌倒的发生情况。采用多变量回归分析确定与再次跌倒相关的变量,并建立风险模型。我们确定了3个等级的新跌倒风险(低、中、高)。结果:共纳入1313例患者;147例患者(11.2%)报告再次跌倒。与再次跌倒风险相关的变量是在指数下降前的12个月内有过跌倒、神经系统疾病、贫血、使用非阿片类镇痛药、在家跌倒、夜间跌倒、跌倒时头部受伤以及从椅子上站起时需要帮助。低、中、高风险患者再次跌倒的概率分别为3.5%、10.5%和23.3%。该模型的判别能力中等:受试者工作特征曲线下面积为0.688 (95% CI, 0.640-0.736)。结论:在急诊科接受意外跌倒治疗的老年人中,每9人中就有1人会在6个月内再次跌倒。有可能确定应对其采取预防措施的高危患者。
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引用次数: 0
Routine laboratory testing to determine if a patient has COVID-19. 通过常规实验室检测确定患者是否患有 COVID-19。
Inge Stegeman, Eleanor A Ochodo, Fatuma Guleid, Gea A Holtman, Bada Yang, Clare Davenport, Jonathan J Deeks, Jacqueline Dinnes, Sabine Dittrich, Devy Emperador, Lotty Hoo, René Spijker, Yemisi Takwoingi, Ann Van den Bruel, Junfeng Wang, Miranda Langendam, Jan Y Verbakel, Mariska M G Leeflang
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引用次数: 0
Main causes of accidental deaths due to avalanches in the Catalan Pyrenees: a review of 50 years. 加泰罗尼亚比利牛斯山雪崩意外死亡的主要原因:50年回顾。
Íñigo Soteras Martínez, Marc Ayala, Josep Maria Casadesús, Glòria Martí Domènech, Joan Carles Trullàs, Robert Blasco Mariño
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引用次数: 0
Emergency department observation of patients with acute heart failure prior to hospital admission: impact on short-term prognosis. 急性心力衰竭患者入院前急诊观察:对短期预后的影响。
María Pilar López Díez, Pere Llorens, Francisco Javier Martín-Sánchez, Víctor Gil, Javier Jacob, Pablo Herrero, Lluís Llauger, Josep Tost, Alfons Aguirre, José Manuel Garrido, Juan Antonio Vega, Marta Fuentes, María Isabel Alonso, María Luisa López Grima, Pascual Piñera, Rodolfo Romero, Francisco Javier Lucas-Imbernón, Juan Antonio Andueza, Javier Povar, Fernando Richard, Carolina Sánchez, Òscar Miró

Objectives: To analyze whether short-term outcomes are affected when patients diagnosed with acute heart failure (AHF) spend time in an emergency department observation unit (EDOU) before hospital admission.

Material and methods: Baseline and emergency episode data were collected for patients diagnosed with AHF in the EDs of 15 Spanish hospitals. We analyzed crude and adjusted associations between EDOU stay and 30-day mortality (primary outcome) and in-hospital mortality and a prolonged hospital stay of more than 7 days (secondary outcomes).

Results: A total of 6597 patients with a median (interquartile range) age of 83 (76-88 years) were studied. Fifty-five percent were women. All were hospitalized for AHF (50% in internal medicine wards, 23% in cardiology, 11% in geriatrics, and 16 in other specialties. Of these patients, 3241 (49%) had had EDOU stays and 3350 (51%) had been admitted immediately, with no EDOU stay. Having an EDOU stay was associated with female sex, dementia or chronic obstructive pulmonary disease, long-term treatment with certain drugs for heart failure, greater baseline deterioration in function, and a higher degree of decompensation. Patients in the EDOU group were more often admitted to an internal medicine ward and had shorter stays; cardiology, geriatric, and intensive care admissions were less likely to have had an EDOU stay. Overall, 30-day mortality was 12.6% (13.7% in the EDOU group and 11.4% in the no-EDOU group; P = .004). In-hospital mortality was 10.4% overall (EDOU, 11.1% and no-EDOU, 9.6%; P = .044). Prolonged hospitalization occurred in 50.0% (EDOU, 48.7% and no-EDOU, 51.2%; P = .046). After adjusting for between-group differences, the EDOU stay was not associated with 30-day mortality (hazard ratio, 1.14; 95% CI, 0.99-1.31). Odds ratios for associations between EDOU stay and in-hospital mortality and prolonged hospital stay, respectively, were 1.09 (95% CI, 0.92-1.29) and 0.91 (95% CI, 0.82-1.01).

Conclusion: Although mortality higher in patients hospitalized for AHF who spend time in an EDO, the association seems to be accounted for by their worse baseline situation and the greater seriousness of the decompensation episode, not by time spent in the EDOU.

目的:分析诊断为急性心力衰竭(AHF)的患者在入院前在急诊科观察单元(EDOU)度过的时间是否会影响其短期预后。材料和方法:收集西班牙15家医院急诊科诊断为AHF的患者的基线和急诊数据。我们分析了EDOU住院时间与30天死亡率(主要结局)、住院死亡率和住院时间超过7天(次要结局)之间的粗相关性和校正相关性。结果:共纳入6597例患者,年龄中位数(四分位数间距)为83岁(76-88岁)。其中55%是女性。所有患者均因AHF住院(50%在内科病房,23%在心脏病科,11%在老年科,16在其他专科)。在这些患者中,3241例(49%)患者有EDOU住院,3350例(51%)患者立即入院,没有EDOU住院。EDOU住院与女性、痴呆或慢性阻塞性肺病、某些心力衰竭药物的长期治疗、更大的基线功能恶化和更高程度的代偿失调有关。EDOU组的患者更常入住内科病房,住院时间更短;心脏科、老年科和重症监护住院患者的EDOU住院率较低。总体而言,30天死亡率为12.6% (EDOU组为13.7%,无EDOU组为11.4%;P = .004)。总体住院死亡率为10.4% (EDOU为11.1%,无EDOU为9.6%;P = .044)。延长住院的发生率为50.0% (EDOU为48.7%,无EDOU为51.2%);P = .046)。在调整组间差异后,EDOU住院时间与30天死亡率无关(风险比,1.14;95% ci, 0.99-1.31)。EDOU住院时间与住院死亡率和延长住院时间之间的比值比分别为1.09 (95% CI, 0.92-1.29)和0.91 (95% CI, 0.82-1.01)。结论:虽然住院治疗AHF的患者在EDO呆了一段时间后死亡率更高,但这种关联似乎是由于他们的基线情况更差和失代偿发作的严重性更大,而不是因为在EDO呆了一段时间。
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引用次数: 0
Differences in clinical signs and severity of intoxication due to street drugs in adolescents and young adults treated in emergency departments. 在急诊科接受治疗的青少年和青壮年街头毒品中毒的临床症状和严重程度的差异
Guillermo Burillo-Putze, Dima Ibrahim-Achi, Lidia Martínez-Sánchez, Miguel Galicia, August Supervía, Jordi Puiguriguer Ferrando, Sebastián Matos Castro, María Ángeles Leciñena, M ª José Venegas de L'Hotellerie, Belén Rodríguez Miranda, Ángel Bajo Bajo, Beatriz Martín-Pérez, Antonio Dueñas-Laita, Ana Ferrer Dufol, Francisco Callado-Moro, Santiago Nogué-Xarau, Òscar Miró

Objectives: To determine whether symptoms and levels of severity of intoxication from street drugs differ between adolescents and young adults who come to hospital emergency departments for treatment.

Material and methods: We studied a consecutive cohort of adolescents (aged 12-17 years) and young adults (aged 18-30 years) who were treated in 11 hospital emergency departments belonging to the Drug Abuse Network of Spanish Hospital Emergency Departments (REDURHE). Sociodemographic and clinical characteristics and level of severity were recorded for comparison between between adolescents and young adults, adjusted for sex, alcohol co-ingestion, and type of drug used. An intoxication was recorded as severe if at least 1 of the following indicators was present: cardiac arrest, tracheal intubation, intensive care unit admission, and in-hospital death.

Results: We included a total of 2181 patients: 249 adolescents (11.4%) and 1932 young adults (88.6%). Alcohol coingestion and use of multiple drugs were less common in adolescents, who had significantly more events related to cannabis (in 81.1% vs 49.0% of young adults) and benzodiazepines (13.3% vs 5.5%). The adolescents had significantly fewer intoxications from the use of cocaine (10.8% vs 45.1%), amphetamines (17.3% vs 32.3%), ketamine (0.4% vs 6.0%) and gamma-hydroxybutyrate (0.4% vs 4.0%). A higher proportion of adolescents than young adults presented with diminished consciousness (23.0% vs 16.9%), but fewer manifested anxiety (15.9% vs 26.3%), palpitations (11.0% vs 19.5%), or chest pain (2.8% vs 9.2%). The pattern of associations was similar in the subgroup of intoxications due to cannabis. The adjusted model confirmed that the adolescents were more likely to have diminished consciousness, with an odds ratio (OR) of 1.851 (95% CI, 1.204-2.844) and less likely to have anxiety (OR, 0.529 (95% CI, 0.347-0.807). Intoxication was severe in 46 patients overall (2.1%); in adolescents and young adults the proportions were 0.8% and 2.3%, respectively (P = 0.129). In adolescents, the OR was 0.568 (95% CI, 0.131-2.468) for severity; for component indicators, the ORs were 0.494 (95% CI, 0.063-3.892) for intubation and 0.780 (95% CI, 0.175-3.475) for intensive care unit admission. No deaths occurred.

Conclusion: Adolescents requiring emergency care for street drug intoxication had co-ingested alcohol or taken multiple drugs less often than young adults. Cannabis was the drug most often used by adolescents, who presented more often with diminished consciousness but less often with anxiety. We detected no differences related to event severity.

目的:确定街头毒品中毒的症状和严重程度在来医院急诊科治疗的青少年和年轻人之间是否存在差异。材料和方法:我们研究了在西班牙医院急诊科药物滥用网络(REDURHE)所属的11家医院急诊科接受治疗的青少年(12-17岁)和年轻人(18-30岁)的连续队列。记录社会人口学和临床特征以及严重程度,以便在青少年和年轻人之间进行比较,并根据性别、酒精共摄入和使用药物类型进行调整。如果出现以下至少1项指标,则记录为严重中毒:心脏骤停、气管插管、重症监护病房住院和院内死亡。结果:我们共纳入2181例患者:249例青少年(11.4%)和1932例青年(88.6%)。青少年中饮酒和使用多种药物的情况较少见,他们与大麻(81.1%对49.0%的年轻人)和苯二氮卓类药物(13.3%对5.5%)相关的事件明显更多。青少年因使用可卡因(10.8%对45.1%)、安非他命(17.3%对32.3%)、氯胺酮(0.4%对6.0%)和-羟基丁酸盐(0.4%对4.0%)而中毒的人数明显减少。青少年表现为意识减退的比例高于年轻人(23.0%比16.9%),但表现为焦虑(15.9%比26.3%)、心悸(11.0%比19.5%)或胸痛(2.8%比9.2%)的比例较少。这种关联模式在大麻中毒亚组中是相似的。调整后的模型证实,青少年更有可能意识减弱,比值比(OR)为1.851 (95% CI, 1.204-2.844),焦虑的可能性更小(OR, 0.529 (95% CI, 0.347-0.807)。46例患者严重中毒(2.1%);青少年和青壮年分别为0.8%和2.3% (P = 0.129)。在青少年中,严重性的OR为0.568 (95% CI, 0.131-2.468);对于组成指标,插管的or值为0.494 (95% CI, 0.063-3.892),重症监护病房入院的or值为0.780 (95% CI, 0.175-3.475)。没有人员死亡。结论:需要紧急护理的街头毒品中毒青少年与年轻人相比,同时摄入酒精或服用多种药物的频率较低。大麻是青少年最常使用的药物,他们更常表现为意识减弱,但较少表现为焦虑。我们没有发现与事件严重程度相关的差异。
{"title":"Differences in clinical signs and severity of intoxication due to street drugs in adolescents and young adults treated in emergency departments.","authors":"Guillermo Burillo-Putze,&nbsp;Dima Ibrahim-Achi,&nbsp;Lidia Martínez-Sánchez,&nbsp;Miguel Galicia,&nbsp;August Supervía,&nbsp;Jordi Puiguriguer Ferrando,&nbsp;Sebastián Matos Castro,&nbsp;María Ángeles Leciñena,&nbsp;M ª José Venegas de L'Hotellerie,&nbsp;Belén Rodríguez Miranda,&nbsp;Ángel Bajo Bajo,&nbsp;Beatriz Martín-Pérez,&nbsp;Antonio Dueñas-Laita,&nbsp;Ana Ferrer Dufol,&nbsp;Francisco Callado-Moro,&nbsp;Santiago Nogué-Xarau,&nbsp;Òscar Miró","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether symptoms and levels of severity of intoxication from street drugs differ between adolescents and young adults who come to hospital emergency departments for treatment.</p><p><strong>Material and methods: </strong>We studied a consecutive cohort of adolescents (aged 12-17 years) and young adults (aged 18-30 years) who were treated in 11 hospital emergency departments belonging to the Drug Abuse Network of Spanish Hospital Emergency Departments (REDURHE). Sociodemographic and clinical characteristics and level of severity were recorded for comparison between between adolescents and young adults, adjusted for sex, alcohol co-ingestion, and type of drug used. An intoxication was recorded as severe if at least 1 of the following indicators was present: cardiac arrest, tracheal intubation, intensive care unit admission, and in-hospital death.</p><p><strong>Results: </strong>We included a total of 2181 patients: 249 adolescents (11.4%) and 1932 young adults (88.6%). Alcohol coingestion and use of multiple drugs were less common in adolescents, who had significantly more events related to cannabis (in 81.1% vs 49.0% of young adults) and benzodiazepines (13.3% vs 5.5%). The adolescents had significantly fewer intoxications from the use of cocaine (10.8% vs 45.1%), amphetamines (17.3% vs 32.3%), ketamine (0.4% vs 6.0%) and gamma-hydroxybutyrate (0.4% vs 4.0%). A higher proportion of adolescents than young adults presented with diminished consciousness (23.0% vs 16.9%), but fewer manifested anxiety (15.9% vs 26.3%), palpitations (11.0% vs 19.5%), or chest pain (2.8% vs 9.2%). The pattern of associations was similar in the subgroup of intoxications due to cannabis. The adjusted model confirmed that the adolescents were more likely to have diminished consciousness, with an odds ratio (OR) of 1.851 (95% CI, 1.204-2.844) and less likely to have anxiety (OR, 0.529 (95% CI, 0.347-0.807). Intoxication was severe in 46 patients overall (2.1%); in adolescents and young adults the proportions were 0.8% and 2.3%, respectively (P = 0.129). In adolescents, the OR was 0.568 (95% CI, 0.131-2.468) for severity; for component indicators, the ORs were 0.494 (95% CI, 0.063-3.892) for intubation and 0.780 (95% CI, 0.175-3.475) for intensive care unit admission. No deaths occurred.</p><p><strong>Conclusion: </strong>Adolescents requiring emergency care for street drug intoxication had co-ingested alcohol or taken multiple drugs less often than young adults. Cannabis was the drug most often used by adolescents, who presented more often with diminished consciousness but less often with anxiety. We detected no differences related to event severity.</p>","PeriodicalId":11644,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":" ","pages":"352-360"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33498113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Description of basic competencies in clinical ultrasound imaging for emergency departments. 急诊科临床超声成像基本能力描述。
Tomás Villén Villegas, Ricardo Campo Linares, José Ramón Alonso Viladot, Roser Martínez Mas, María José Luque Hernández, Miriam Ruiz Durán, Alberto Oviedo García, Joaquín Antonio Álvarez Gregori, Mariano Aguilar Mulet, Luis Campos Caubet, Linder Cárdenas Bravo, David Chaparro Pardo, Jaldún Chehayeb Morán, José Vicente Esteban Velasco, Manuel Ferreiro Gómez, Daniel García Martín, Iván García Suárez, Adrián Martínez Hernández, Ángel Hernández Galán, Javier Millán Soria, José Félix Martínez López, José Francisco Rodríguez García, Inés Ruano Peña, Francisco José Salvador Suárez, Susana Simó Meléndez, Juan José Zafra Sánchez, Ramón Nogué Bou

Text: Recent years have seen great advances in the use of clinical ultrasound imaging in both hospital emergency departments and out-of-hospital settings. However, all new techniques require up-to-date definitions of competencies relevant to the clinical realities of different specialties and the geographic settings in which specialists work. To that end, a group of experts in clinical ultrasound reviewed the evidence available in the literature and strictly applied the Delphi method to define the competencies relevant to emergency physicians. The group worked with the starting premise that clinical ultrasound imaging should be a common competency across the specialty.

近年来,在医院急诊科和院外环境中使用临床超声成像取得了巨大进展。然而,所有的新技术都需要与不同专业的临床现实和专家工作的地理环境相关的能力的最新定义。为此,一组临床超声专家回顾了文献中现有的证据,并严格应用德尔菲法来定义与急诊医生相关的能力。小组工作的前提是临床超声成像应该是整个专业的共同能力。
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引用次数: 0
Change of pace. 改变节奏。
Isabel Luque
{"title":"Change of pace.","authors":"Isabel Luque","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11644,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":" ","pages":"396-397"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33498117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is spontaneous pneumomediastinum really spontaneous? 自发性纵隔气肿真的是自发性的吗?
Sebastián Campbell-Quintero, Santiago Campbell-Quintero, Santiago Campbell-Silva
{"title":"Is spontaneous pneumomediastinum really spontaneous?","authors":"Sebastián Campbell-Quintero,&nbsp;Santiago Campbell-Quintero,&nbsp;Santiago Campbell-Silva","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11644,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":" ","pages":"407-408"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33498124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Derivation and validation of new prehospital phenotypes for adults with COVID-19. 成人COVID-19新院前表型的推导和验证
Ana Alberdi-Iglesias, Raúl López-Izquierdo, Guillermo J Ortega, Ancor Sanz-García, Carlos Del Pozo Vegas, Juan F Delgado Benito, Francisco Martín-Rodríguez

Objectives: To characterize phenotypes of prehospital patients with COVID-19 to facilitate early identification of at-risk groups.

Material and methods: Multicenter observational noninterventional study of a retrospective cohort of 3789 patients, analyzing 52 prehospital variables. The main outcomes were 4 clusters of prehospital variables describing the phenotypes. Secondary outcomes were hospitalization, mechanical ventilation, admission to an intensive care unit, and cumulative mortality inside or outside the hospital on days 1, 2, 3, 7, 14, 21, and 28 after hospitalization and after start of prehospital care.

Results: We used a principal components multiple correspondence analysis (factor analysis) followed by decomposition into 4 clusters as follows: cluster 1, 1090 patients (28.7%); cluster 2, 1420 (37.4%); cluster 3, 250 (6.6%), and cluster 4, 1029 (27.1%). Cluster 4 was comprised of the oldest patients and had the highest frequencies of residence in group facilities and low arterial oxygen saturation. This group also had the highest mortality (44.8% at 28 days). Cluster 1 was comprised of the youngest patients and had the highest frequencies of smoking, fever, and requirement for mechanical ventilation. This group had the most favorable prognosis and the lowest mortality.

Conclusion: Patients with COVID-19 evaluated by emergency medical responders and transferred to hospital emergency departments can be classified into 4 phenotypes with different clinical, therapeutic, and prognostic characteristics. The phenotypes can help health care professionals to quickly assess a patient's future risk, thus informing clinical decisions.

目的:了解院前患者COVID-19的表型特征,以便早期识别高危人群。材料和方法:对3789例患者进行回顾性多中心观察性非介入性研究,分析52个院前变量。主要结局是描述表型的4组院前变量。次要结局是住院、机械通气、入住重症监护病房,以及住院后和院前护理开始后第1、2、3、7、14、21和28天院内外的累积死亡率。结果:采用主成分多对应分析(因子分析)将患者分为4类:第1类1090例(28.7%);聚类2 1420例(37.4%);集群3,250(6.6%)和集群4,1029(27.1%)。第4组由年龄最大的患者组成,在集体设施中居住的频率最高,动脉氧饱和度低。该组28天死亡率最高(44.8%)。第1组由最年轻的患者组成,吸烟、发烧和需要机械通气的频率最高。该组预后良好,死亡率最低。结论:经急救人员评估并转至医院急诊科的COVID-19患者可分为4种表型,具有不同的临床、治疗和预后特征。表型可以帮助医疗保健专业人员快速评估患者未来的风险,从而为临床决策提供信息。
{"title":"Derivation and validation of new prehospital phenotypes for adults with COVID-19.","authors":"Ana Alberdi-Iglesias,&nbsp;Raúl López-Izquierdo,&nbsp;Guillermo J Ortega,&nbsp;Ancor Sanz-García,&nbsp;Carlos Del Pozo Vegas,&nbsp;Juan F Delgado Benito,&nbsp;Francisco Martín-Rodríguez","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To characterize phenotypes of prehospital patients with COVID-19 to facilitate early identification of at-risk groups.</p><p><strong>Material and methods: </strong>Multicenter observational noninterventional study of a retrospective cohort of 3789 patients, analyzing 52 prehospital variables. The main outcomes were 4 clusters of prehospital variables describing the phenotypes. Secondary outcomes were hospitalization, mechanical ventilation, admission to an intensive care unit, and cumulative mortality inside or outside the hospital on days 1, 2, 3, 7, 14, 21, and 28 after hospitalization and after start of prehospital care.</p><p><strong>Results: </strong>We used a principal components multiple correspondence analysis (factor analysis) followed by decomposition into 4 clusters as follows: cluster 1, 1090 patients (28.7%); cluster 2, 1420 (37.4%); cluster 3, 250 (6.6%), and cluster 4, 1029 (27.1%). Cluster 4 was comprised of the oldest patients and had the highest frequencies of residence in group facilities and low arterial oxygen saturation. This group also had the highest mortality (44.8% at 28 days). Cluster 1 was comprised of the youngest patients and had the highest frequencies of smoking, fever, and requirement for mechanical ventilation. This group had the most favorable prognosis and the lowest mortality.</p><p><strong>Conclusion: </strong>Patients with COVID-19 evaluated by emergency medical responders and transferred to hospital emergency departments can be classified into 4 phenotypes with different clinical, therapeutic, and prognostic characteristics. The phenotypes can help health care professionals to quickly assess a patient's future risk, thus informing clinical decisions.</p>","PeriodicalId":11644,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":"34 5","pages":"361-368"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9459681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal blood pressure thresholds during vasopressors weaning: The U-Shaped pattern. 血管加压药物脱机期间的最佳血压阈值:u型模式。
Ovidiu Chioncel, Laura Antohi, Serban Bubenek
{"title":"Optimal blood pressure thresholds during vasopressors weaning: The U-Shaped pattern.","authors":"Ovidiu Chioncel,&nbsp;Laura Antohi,&nbsp;Serban Bubenek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11644,"journal":{"name":"Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias","volume":"34 5","pages":"329-330"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9459684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias
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