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The Australian and New Zealand journal of psychiatry最新文献

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Depression and attempted suicide. 抑郁症和自杀未遂。
Pub Date : 1989-09-01 DOI: 10.1177/000486748902300310
R. Goldney
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引用次数: 2
Depot neuroleptic medication and serum levels by radioreceptor assay: prolactin concentration, electrocardiogram abnormalities and six-month outcome. 贮存抗精神病药物和血清放射受体水平测定:催乳素浓度、心电图异常和六个月预后。
Pub Date : 1987-09-01 DOI: 10.3109/00048678709160929
J. Turbott, J. Villiger, L. Hunter
Twenty-six chronic schizophrenic patients on well-established depot neuroleptic regimes with stable doses (16 on fluphenazine decanoate, 10 on flupenthixol decanoate) had serum neuroleptic levels measured by radioreceptor assay (RRA) and were followed for six months. The serum prolactin (PRL) concentration and resting electrocardiogram (ECG) were also taken at the beginning of the study period. Correlations had previously been noted between RRA measured neuroleptic levels and outcome in both acute and chronic patients on oral medication. However, in this study of depot medication no significant correlations were found between serum neuroleptic concentration, serum prolactin concentration and the clinical state or outcome. The prevalence (33%) and type of ECG abnormality observed was similar to that previously reported.
26例慢性精神分裂症患者采用稳定剂量(氟非那嗪癸酸16例,氟哌辛醇癸酸10例)的长效抗精神病药物治疗方案,用放射受体测定法(RRA)测定血清抗精神病药物水平,并随访6个月。研究开始时测定血清催乳素(PRL)浓度及静息心电图(ECG)。在口服药物的急性和慢性患者中,RRA测量的抗精神病药水平与预后之间存在相关性。然而,在本研究中,血清抗精神病药浓度、血清催乳素浓度与临床状态或结局之间未发现显著相关性。心电图异常的发生率(33%)和类型与先前报道相似。
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引用次数: 1
Post-traumatic stress disorder in Japanese prisoners of war. 日本战俘的创伤后应激障碍。
Pub Date : 1987-08-01 DOI: 10.1176/AJP.144.8.1110
I. P. Watson
Stephen T icehurs t , Training Fellow in Psychogeriatrics, NSW Institute of Psychiatry, Hunter Regional Mental Health Services, Newcastle NSW 2300: In a comprehensive review of the assessment of dementia, Dr McLean refers to the use of antipsychotics in dementia. [Journal 1987; 21: 284-3041. He points out the lack of agreement in the literature as to the indications and efficacy of these drugs. His review of their use in relation to delusions and hallucinations does not, however, highlight the methodological problems in the studies published to date. These have been generally retrospective case reviews, open, uncontrolled and with a failure to define what exactly constitutes a delusion in a dementing population, [e.g. Leuchter and Spar 19851. Others [Cummings 19851, although prospective, have used a small number of highly selected, diagnostically heterogeneous patients and not used control groups or provided blind assessment uf their treatment. In Cummings' series of 20 patients only 4 had Alzheimer's disease. These all had simple or transient paranoid beliefs. He does not tabulate the results to justify his assertion that simple delusions respond best to antipsychotics. The only relevant case history presented is that of a patient with Alzheimer's disease and a simple paranoid "delusion" that disappeared without treatment. Most antipsychotics used in dementing patients are probably used in institutions for the control of behavioural symptoms such as agitation, non-cooperativeness, wandering and aggression. These uses have been subject to better evaluation and have been reviewed recently [Risse & Barnes 19861. The literature would suggest that as many as 60% or more of the patients with dementia who receive anti-psychotics are gaining little benefit from its prescription for these purposes. It is also apparent that the risks of side effects such as tardive dyskinesia, hip fractures etc. are greatly increased in the dementing elderly. Such risks need to be balanced against the perceived benefits and alternatives to drug management should be sought. References: CUMMINGS JL [ 19851 Organic delusions: phenomenology, anatomical correlations and review. British Journal of Psychiatry 146. 18497. LEUCHTER AF & SPAR JE [I9851 The late onset psychoses: clinical and diagnostic features. Journal of Nervous and Mental Diseases
Stephen T . icehurs T,新南威尔士州纽卡斯尔亨特地区精神卫生服务精神病学研究所老年精神病学培训研究员:在对痴呆症评估的全面回顾中,麦克莱恩博士提到了抗精神病药物在痴呆症中的使用。[杂志1987;21日:284 - 3041。他指出,这些药物的适应症和疗效在文献中缺乏一致性。然而,他对药物用于治疗妄想和幻觉的回顾并没有强调迄今为止发表的研究中方法论上的问题。这些通常是回顾性的病例回顾,公开的,不受控制的,并且未能定义痴呆人群中的妄想的确切构成,[例如Leuchter和Spar, 19851]。其他研究[Cummings 19851]虽然具有前瞻性,但使用了少数经过高度筛选、诊断异质性的患者,而没有使用对照组或对其治疗进行盲目评估。在卡明斯的20名患者中,只有4人患有阿尔茨海默病。这些人都有简单或短暂的偏执信念。他没有将结果制成表格来证明他的论断,即简单的妄想对抗精神病药物的效果最好。唯一相关的病史是一个患有阿尔茨海默病的病人,一个简单的偏执“妄想”,未经治疗就消失了。大多数用于痴呆患者的抗精神病药物可能在机构中用于控制行为症状,如躁动,不合作,徘徊和攻击。这些用途已经得到了更好的评价,并在最近得到了回顾[Risse & Barnes, 19861]。文献表明,多达60%或更多的接受抗精神病药物治疗的痴呆症患者并没有从处方中获得多少好处。同样明显的是,老年痴呆患者出现迟发性运动障碍、髋部骨折等副作用的风险大大增加。需要将这些风险与可感知的益处进行权衡,并寻求替代药物管理的方法。参考文献:CUMMINGS JL[19851]。有机错觉:现象学、解剖学相关性及综述。英国精神病学杂志[j]。18497. 迟发性精神病的临床和诊断特点[j][1998]。神经与精神疾病杂志
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引用次数: 4
The emperor's new clothes. 皇帝的新衣。
Pub Date : 1984-01-01 DOI: 10.1163/9789004489981_011
J. Gelb
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引用次数: 0
A study of aetiological factors at critical periods of development in autistic children. 自闭症儿童发育关键期病因因素的研究。
Pub Date : 1974-03-01 DOI: 10.1080/00207411.1974.11448647
S. Williams, J. Harper
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引用次数: 3
Mixed-race society in Port Moresby. 莫尔兹比港的混血社会。
Pub Date : 1969-03-01 DOI: 10.2307/2799315
W. B. Burton-Bradley
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引用次数: 7
Maternal deprivation. 母爱剥夺。
Pub Date : 1900-01-01 DOI: 10.4135/9781483365817.n825
N. Mcconaghy
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引用次数: 0
The psychiatric nurse in liaison psychiatry. 精神科联络护士。
Pub Date : 1900-01-01 DOI: 10.1177/000486748902300312
R. Gribble, R. T. White, G. Wicks, J. Reed, J. Kurt
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引用次数: 6
Ganser syndrome. 甘塞尔综合症。
Pub Date : 1900-01-01 DOI: 10.1177/000486748902300311
N. Parker
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引用次数: 0
The immune system and infection may be involved in the effects of psychological factors on the cardiovascular system. 心理因素对心血管系统的影响可能涉及免疫系统和感染。
Pub Date : 1900-01-01 DOI: 10.1046/j.1440-1614.2000.0719g.x
L. Sher
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引用次数: 1
期刊
The Australian and New Zealand journal of psychiatry
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