Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-044
Andrew E Massey
{"title":"Abstract PO-044: Mechanobiological analysis of human patient pancreatic cancer tissues and the effect of cellular transmembrane mucins on glycocalyx-actomyosin mechanics","authors":"Andrew E Massey","doi":"10.1158/1538-7445.panca21-po-044","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-044","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122202388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-036
D. Restifo, A. Kulkarni, Caleb Schimke, J. McDermott, Umesh Kathad, K. Bhatia, Panna Sharma, I. Astsaturov
{"title":"Abstract PO-036: LP184, a novel alkylating agent, is highly effective in pancreatic cancers with DNA damage repair defects","authors":"D. Restifo, A. Kulkarni, Caleb Schimke, J. McDermott, Umesh Kathad, K. Bhatia, Panna Sharma, I. Astsaturov","doi":"10.1158/1538-7445.panca21-po-036","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-036","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122429593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-034
A. Alahmari, Carla Schwarz, Emily Paterson, S. Venkat, A. Tisdale, Michael E. Feigin
{"title":"Abstract PO-034: CPSF3 inhibition halts pancreatic cancer cell proliferation by limiting core histone supplies","authors":"A. Alahmari, Carla Schwarz, Emily Paterson, S. Venkat, A. Tisdale, Michael E. Feigin","doi":"10.1158/1538-7445.panca21-po-034","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-034","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122193878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-057
Bo Zhang, Fei Teng, Nengming Lin
{"title":"Abstract PO-057: Targeting ErbB2 degradation via the ubiquitin–proteasome pathway to inhibit the metastasis of pancreatic cancer","authors":"Bo Zhang, Fei Teng, Nengming Lin","doi":"10.1158/1538-7445.panca21-po-057","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-057","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130039456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-055
S. Tsai, E. Borazanci, M. Gulley, N. Rashid, J. Merker, A. Khan, Phillip Chisholm, Bryan C. Hunt, T. Giorgadze, W. Hall, M. Kamgar, Douglas B. Evans, J. Yeh
{"title":"Abstract PO-055: Phase II clinical trial of subtype directed neoadjuvant therapy in patients with localized pancreatic cancer","authors":"S. Tsai, E. Borazanci, M. Gulley, N. Rashid, J. Merker, A. Khan, Phillip Chisholm, Bryan C. Hunt, T. Giorgadze, W. Hall, M. Kamgar, Douglas B. Evans, J. Yeh","doi":"10.1158/1538-7445.panca21-po-055","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-055","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126846323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-ia-008
P. Phillips
{"title":"Abstract IA-008: The KPC model has helped advance pancreatic cancer therapy: Disagree","authors":"P. Phillips","doi":"10.1158/1538-7445.panca21-ia-008","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-ia-008","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130757373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-056
A. Zhang, Jenny C. C. Yang, Twan J. J. de Winter, D. Schaeffer, Janel L. Kopp, James D. Johnson
{"title":"Abstract PO-056: Insulin receptor signaling in pancreatic acinar cells contributes to pancreatic cancer development","authors":"A. Zhang, Jenny C. C. Yang, Twan J. J. de Winter, D. Schaeffer, Janel L. Kopp, James D. Johnson","doi":"10.1158/1538-7445.panca21-po-056","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-056","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124833752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-037
Kaitlin M. Dailey, Krysten E. Vance, Kyle L. McAndrews, R. Jacobson, Jandro Delgado, Paige R. Johnson, Taylor M. Woolery, M. Orr, Jiha Kim, S. Mallik, K. Bayles, M. Hollingsworth, A. Brooks
{"title":"Abstract PO-037: Development of an RGD CRISPR-modified Clostridium novyi NT spores as an intravenous oncotherapy","authors":"Kaitlin M. Dailey, Krysten E. Vance, Kyle L. McAndrews, R. Jacobson, Jandro Delgado, Paige R. Johnson, Taylor M. Woolery, M. Orr, Jiha Kim, S. Mallik, K. Bayles, M. Hollingsworth, A. Brooks","doi":"10.1158/1538-7445.panca21-po-037","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-037","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130080851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-047
N. Ndemazie, Andriana Inkoom, Xue Y. Zhu, Edward Agyare
{"title":"Abstract PO-047: Optimizing the efficacy of 5-FU as a chemotherapeutic agent in advanced pancreatic ductal adenocarcinoma (PDAC) using MIAPaCa-2 and PANC-1 cells","authors":"N. Ndemazie, Andriana Inkoom, Xue Y. Zhu, Edward Agyare","doi":"10.1158/1538-7445.panca21-po-047","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-047","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124010217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-15DOI: 10.1158/1538-7445.panca21-po-040
J. Grahovac, M. Pavlovic, Marija Ostojić, K. Živić, D. Galun, T. Srdić-Rajić
{"title":"Abstract PO-040: Nischarin is expressed in pancreatic ductal adenocarcinoma and is a potential target for drug repurposing","authors":"J. Grahovac, M. Pavlovic, Marija Ostojić, K. Živić, D. Galun, T. Srdić-Rajić","doi":"10.1158/1538-7445.panca21-po-040","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-040","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"450 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134351357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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