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Volume Index 物量指数
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2003-06-01 DOI: 10.1177/0533316404047796
Samir Amin
AUTHOR INDEX Alderdice, Lord.‘Response to Lecture by Ivan Urlić’, 472–476. Arnott, B. Book Review, ‘Inconceivable Conceptions. Psychological Aspects of Infertility and Reproductive Technology’, J. Haynes and J. Miller (eds), 567–568. Barwick, N. ‘Bearing Witness: Group Analysis as Witness Training in Action’, 121–136. Behr, H. ‘Commentary on “Drawing the Isolate into the Group Flow” by Louis Ormont’, 76–81. Behr, H. ‘Commentary on Article by Hinshelwood’, 333–338. Billow, R. M. ‘Working Relationally with the Adolescent in Group’, 187–200. Blackwell, R.D. ‘Freedom and Autonomy in Mind, Commentary on “A case for Mind” by Patrick de Maré and Robert Schöllberger, and “Mind” by S. H. Foulkes’, 353–357. Bledin, K. ‘What’s in a Name? Foulkes, Identity and the Social Unconscious’, 477–489. Brunori, L. (see also Gibin, A.M., Miglioli, M. and Bussandri, M.) ‘Analysis of the Therapeutic Course of an Eating Disorders Group’, 387–399; ‘28th S.H. Foulkes Annual Lecture: President’s Introduction’, 451–452. Burman, E. ‘Boundary Objects and Group Analysis: Between Psychoanalysis and Social Theory’, 361–379. Burman, E. ‘Organising for Change? Group-analytic Perspectives on A Feminist Action Research Project’, 91–108. Bush, M (see also Wennberg, P., Weinryb, R.M., Saxon, L., Göransson, S. and Skarbrandt, E.) ‘Personality Levels of Psychological Distress and Premature Termination of Psychodynamic Group Therapy: Results from a Prospective Longitudinal Study’, 179–185. Bussandri, M. (see also Brunori, L., Gibin, A.M., and Miglioli, M.) ‘Analysis of the Therapeutic Course of an Eating Disorders Group’, 387–399. de Maré, P. (see also Schöllberger, R.) ‘A Case For Mind’, 339–352. Diamond, N. Obituary, Hans Cohn, 564–566. Eszik, J. (see also Kis, G. and Terenyi, Z.) ‘Hierarchy And/Or Reflectivity: The Role of Groups in the Function of Psychiatric Wards’, 45–63. Foulkes, E. ‘Response to “What’s in a Name? Foulkes, Identity and the Social Unconscious” by Kenneth Bledin’, 490–491. Friedman, R. ‘Dream-telling as a Request for Containment – Reconsidering the Groupanalytic Approach to the Work with Dreams’, 508–524. Gibin, A.M., (see also Brunori, L. Miglioli, M. and Bussandri, M.) ‘Analysis of the Therapeutic Course of an Eating Disorders Group’, 387–399. Göransson, S. (see also Wennberg, P., Weinryb, R.M., Saxon, L., Bush, M and Skarbrandt, E.) ‘Personality Levels of Psychological Distress and Premature Termination Of Psychodynamic Group Therapy: Results From a Prospective Longitudinal Study’, 179–185.
作者索引奥尔德代斯,勋爵。《对Ivan urliki演讲的回应》,472-476页。阿诺特,B.书评,《不可思议的概念》。不孕不育和生殖技术的心理方面',J. Haynes和J. Miller(主编),567-568。巴威克,N.“作证:作为行动中的证人训练的群体分析”,121-136页。评论路易斯·奥蒙特的《将孤立者引入群体流》,第76-81页。Behr, H. '对Hinshelwood文章的评论',333-338。比洛,r.m.,《与群体中的青少年的工作关系》,187-200。Blackwell, R.D.,《心灵中的自由与自主》,对Patrick de mar和Robert Schöllberger的《心灵案例》和S. H. Foulkes的《心灵》的评论,353-357页。该死,k,名字有什么用?《身份与社会无意识》,第477-489页。Brunori, L.(也见Gibin, a.m., Miglioli, M.和Bussandri, M.),《饮食失调组的治疗过程分析》,387-399;第28届S.H. Foulkes年度演讲:校长介绍,第451-452页。边界对象和群体分析:在精神分析和社会理论之间,第361-379页。E. Burman,《组织变革?》《一个女性主义行动研究项目的群体分析视角》,第91-108期。Bush, M(也见Wennberg, P., Weinryb, r.m., Saxon, L., Göransson, S.和Skarbrandt, E.),“心理困扰的人格水平和心理动力团体治疗的过早终止:来自前瞻性纵向研究的结果”,179-185。Bussandri, M.(另见Brunori, L., Gibin, a.m.和Miglioli, M.),《饮食失调组的治疗过程分析》,第387-399页。de mardeur, P.(另见Schöllberger, R.),《A Case For Mind》,339-352页。讣告,汉斯·科恩,564-566。Eszik, J.(另见Kis, G.和Terenyi, Z.),“层级和/或反射率:群体在精神科病房功能中的作用”,第45-63页。E. Foulkes对“名字里有什么?”《身份与社会无意识》,Kenneth Bledin著,490-491页。Friedman, R.,《作为遏制要求的梦境讲述——重新考虑与梦一起工作的群体分析方法》,第508-524页。Gibin, a.m.(另见Brunori, L. Miglioli, M.和Bussandri, M.),《饮食失调组的治疗过程分析》,第387-399页。Göransson, S.(另见Wennberg, P., Weinryb, r.m., Saxon, L., Bush, M.和Skarbrandt, E.)“心理困扰的人格水平和心理动力团体治疗的过早终止:来自前瞻性纵向研究的结果”,179-185。
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引用次数: 0
Dietary vitamin E and physical exercise: II. Antioxidant status and lipofuscin-like substances in aging rat heart. 膳食维生素E与体育锻炼:2。衰老大鼠心脏抗氧化状态及脂褐素样物质。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2003-03-01
S Asha Devi, S Prathima, M V V Subramanyam

The heart faces a high risk of free radical injury owing to a slow generation of antioxidant (AO) enzymes by its cells. A general decline in this system may be another reason for the development of age-related diseases. Although the correlation between aging and exercise has been studied extensively, these studies have produced conflicting data on the effects of vitamin E on the aging heart, when it is introduced as an intervening factor. To investigate these effects, we determined the activities of antioxidant enzymes (AOEs) such as superoxide dismutase (SOD) and catalase (CAT), lipid peroxidation (LP), lipofuscin (LF)-like autofluorescent substances and vitamin E content in the left and right ventricles (LV and RV) of the heart in male Wistar albino rats of 4-(young adults), 8-(old adults), 12-(middle-age) and 22-mos(old) of age. Animals were orally supplemented with vitamin E and allowed to swim for 30 min/day, 5 days/week and for a total period of 60 days. Exercise training in all the age groups except the old was effective in upregulating the SOD activity. Old trainees showed an increase in SOD activity when supplemented with vitamin E. In the 22-mo-olds, a remarkable decrease in CAT activity was seen. Exercise by itself upregulated the CAT as well as SOD activity in all age groups except the old wherein vitamin E was effective in increasing the activities of AOEs. Supplementation significantly reduced LP as evidenced by lowered malondialdehyde (MDA) and LF-like autofluorescent substances in the trained as well as sedentary rats. Tissue vitamin E content was low in the swim trainees that were not supplemented. This change, well emphasized in the trainee groups of 22-mo-old suggests the probable utilization of vitamin E in keeping free radicals at bay. Our results suggest that vitamin E can stand out as a significant tool in ameliorating the declining AO defense in the old rats.

由于细胞产生抗氧化(AO)酶的速度缓慢,心脏面临着自由基损伤的高风险。该系统的普遍衰退可能是与年龄有关的疾病发展的另一个原因。尽管人们对衰老和运动之间的关系进行了广泛的研究,但当维生素E作为一种干预因素被引入时,这些研究产生了相互矛盾的数据,即维生素E对衰老心脏的影响。为了研究这些影响,我们测定了4岁(青年)、8岁(老年)、12岁(中年)和22岁(老年)雄性Wistar白化大鼠心脏左、右心室(LV和RV)的抗氧化酶(AOEs)如超氧化物歧化酶(SOD)和过氧化氢酶(CAT)、脂质过氧化(LP)、脂褐素(LF)样自身荧光物质的活性和维生素E含量。动物口服补充维生素E,并允许游泳30分钟/天,5天/周,共60天。除老年人外,各年龄组运动训练均能有效上调SOD活性。年龄较大的受训者在补充维生素e后,SOD活性增加。在22个月大的受训者中,CAT活性显著下降。运动本身上调了所有年龄组的CAT和SOD活性,但老年人除外,其中维生素E可有效增加AOEs的活性。通过降低训练和久坐大鼠的丙二醛(MDA)和lf样自身荧光物质,补充剂显著降低了LP。未补充维生素E的游泳练习者组织维生素E含量较低。这种变化在22岁的受试人群中得到了很好的强调,这表明维生素E可能在抑制自由基方面发挥了作用。我们的研究结果表明,维生素E可以作为改善老年大鼠AO防御能力下降的重要工具。
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引用次数: 0
Time of our Lives: Tom Kirkwood; New York, Oxford University Press, 1999, 277 pages, ISBN 0-19-512824-9 (US$ 27.50) 《我们生命的时光》:汤姆·柯克伍德;纽约,牛津大学出版社,1999年,277页,ISBN 0-19-512824-9(27.50美元)
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2000-02-01 DOI: 10.1016/S0531-5565(99)00086-8
H. Warner
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引用次数: 0
Atherosclerosis is a paradigmatic disease of the elderly, the roots of which are laid in youth, whereas the clinically manifested consequences become evident at old age. 动脉粥样硬化是老年人的典型疾病,其根源在青年时期奠定,而临床表现的后果在老年时变得明显。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1999-07-01
G Wick, Q Xu
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引用次数: 0
Atherosclerosis--an autoimmune disease. 动脉粥样硬化是一种自身免疫性疾病
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1999-07-01
G Wick, Q Xu

Immune-inflammatory processes are increasingly discussed as possible pathogenetic factors involved in the development of atherosclerosis. Here, we summarize data on which we have built our "immunological" hypothesis of atherogenesis. This concept is based on the observation that nearly everybody shows protective cellular and humoral immune reactions against microbial heat shock protein 60 (HSP 60). Because a high degree of antigenic homology exists between microbial (viral, bacterial, parasitic) and human HSP 60, this protective immunity may have to be "paid for" by the danger of cross-reactivity with human HSP 60 that is expressed by endothelial cells of stressed arteries. Arterial endothelial cells are more prone to produce HSP 60 and various adhesion molecules upon exposure to stress factors, including classical risk factors for atherosclerosis, due to their life-long exposure to the high arterial as compared to venous blood pressure. Also, endothelial cells are the first potential targets encountered by circulating HSP 60-specific T cells or antibodies. This concept not only opens new avenues for diagnostic approaches, but also may form the basis for new ways of therapeutic intervention.

免疫炎症过程作为动脉粥样硬化发展中可能的致病因素被越来越多地讨论。在这里,我们总结了我们建立动脉粥样硬化的“免疫学”假设的数据。这一概念是基于观察到几乎每个人都表现出对微生物热休克蛋白60 (HSP 60)的保护性细胞和体液免疫反应。由于微生物(病毒、细菌、寄生虫)和人类热休克蛋白60之间存在高度的抗原同源性,这种保护性免疫可能不得不以与应激动脉内皮细胞表达的人类热休克蛋白60发生交叉反应的危险“付出代价”。相对于静脉压,动脉内皮细胞在暴露于应激因素(包括动脉粥样硬化的经典危险因素)时更容易产生HSP 60和各种粘附分子。此外,内皮细胞是循环HSP 60特异性T细胞或抗体遇到的第一个潜在目标。这一概念不仅为诊断方法开辟了新的途径,而且可能形成新的治疗干预方法的基础。
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引用次数: 0
Proceedings of the 4th International Symposium on the Neurobiology and Neuroendocrinology of Aging. Bregenz, Austria, July 26-31, 1998. 第四届老年神经生物学和神经内分泌学国际学术研讨会论文集。1998年7月26日至31日,奥地利布雷根茨。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1998-11-01
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引用次数: 0
Special issue: A tribute to Alex Comfort. 特刊:向亚历克斯·康福特致敬。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1998-01-01
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引用次数: 0
Proceedings of the 3rd International Symposium on The Neurobiology and Neuroendocrinology of Aging. Bregenz, Austria, July 21-26, 1996. 第三届老年神经生物学和神经内分泌学国际研讨会论文集。布雷根茨,奥地利,1996年7月21日至26日。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1997-07-01
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引用次数: 0
Proceedings of the 2nd International Conference on Animal Models for Aging Research. Kyoto, Japan, May 12-19, 1995. 第二届老龄动物模型国际会议论文集。1995年5月12日至19日,日本京都。
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1997-01-01
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引用次数: 0
Molecular basis of aging by Alvaro Macieira-Coelho, Editor, CRC Press, Boca Raton, FL, 1995, 528 pages, ISBN: 0-849-4786-6, Price: U.S. $149.95/outside U.S. $179.95 《老化的分子基础》Alvaro Macieira-Coelho著,编辑,CRC出版社,佛罗里达州博卡拉顿,1995年,528页,ISBN: 0-849-4786-6,价格:149.95美元/境外179.95美元
IF 3.9 3区 医学 Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 1996-07-01 DOI: 10.1016/0531-5565(96)00010-1
J. Campisi
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引用次数: 0
期刊
Experimental Gerontology
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