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Effect of Single Course Versus Repeated Single Course of Antenatal Corticosteroid (Dexamethasone) in Preterm Premature Rupture of Membranes on Neonatal Respiratory Outcome "Randomized Control Trials" 单疗程与重复单疗程地塞米松治疗早产儿胎膜早破对新生儿呼吸结局的影响“随机对照试验”
Pub Date : 2022-08-01 DOI: 10.21608/ebwhj.2022.143871.1180
Magdy Abd El- Gawad, Alaa Elsewafy, L. Farid
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引用次数: 0
Recombinant Factor VII for the Conservative Management Trials of Intractable Postpartum Haemorrhage: Is it a Drug Effect, Operator Experience or Inherent Result of the Aetiology 重组因子VII在难治性产后出血保守治疗试验中的应用:是药物作用、操作人员经验还是病因的固有结果
Pub Date : 2022-08-01 DOI: 10.21608/ebwhj.2022.128004.1174
Tarek El Azizi, Doaa Alaa Eldin
Aim: This monocentric retrospective study aimed at the evaluation of outcome of the parturients with intractable postpartum haemorrhage (P.P.H.) after the administration of recombinant activated factor VII (rFVIIa) to preserve the uterus. Materials and Methods : this is a retrospective study conducted in a tertiary hospital . 41 patients were selected based on the inclusion criteria of both suffering from postpartum hemorrhage and received recombinant activated factor VII (rFVIIa). Patients were divided into group A who were managed by senior staff and group B who had started their management by junior staff and senior staff was called later for the case. Data was retrieved from patients’ records during 2019. All patients had a preliminary evaluation and classic management measures for postpartum hemorrhage either in the emergency department or during planned cesarean section. If are still bleeding, patients were infused with rFVIIa. If the uterine bleeding didn't stop, conservative management was cancelled, and abdominal hysterectomy was done. In all cases, postpartum mortality was determined. Results: The study included 41 parturient with P.P.H. with a mean age of 30.8±5.4 years. Eighteen patients had a cesarean section (C.S.), of whom 8 had successfully conserved the uterus, and 10 patients had a lifesaving hysterectomy using rFVIIa. On the other hand, 23 patients had been complicated with intractable postpartum haemorrhage. Twenty patients successfully had conservative management after using rFVIIa, and 3 patients had failed conservative management after using rFVIIa, and hysterectomy was lifesaving. Regarding 7-day postpartum mortality, one patient died with an intractable haemorrhage with delayed hysterectomy. Conclusion: The operator seniority and experience is more important than the use of rFVIIa to achieve conservative management of cases suffering from or at great risk of postpartum hemorrhage and to reduce patients mortality.
目的:本单中心回顾性研究旨在评价顽固性产后出血(P.P.H.)患者应用重组活化因子VII (rFVIIa)保子宫后的预后。材料与方法:本研究是在某三级医院进行的回顾性研究。根据同时存在产后出血和接受重组活化因子(rFVIIa)治疗的纳入标准,选择41例患者。患者分为A组由高级医护人员管理,B组由初级医护人员开始管理,高级医护人员稍后接诊。数据是从2019年的患者记录中检索的。所有患者在急诊科或计划剖宫产时均有产后出血的初步评估和经典处理措施。如果仍在出血,则向患者输注rFVIIa。若子宫出血仍未停止,则取消保守治疗,行腹部子宫切除术。在所有病例中,都确定了产后死亡率。结果:本组共41例妊高征产妇,平均年龄30.8±5.4岁。18例患者行剖宫产术(C.S.),其中8例成功保存子宫,10例患者使用rFVIIa进行了挽救生命的子宫切除术。另一方面,23例患者合并难治性产后出血。20例术后保守治疗成功,3例术后保守治疗失败,子宫切除术挽救了患者的生命。关于产后7天死亡率,1例患者死于难治性出血并延迟子宫切除术。结论:手术人员的资历和经验比使用rFVIIa更能实现对产后出血或产后出血高危患者的保守治疗,降低患者死亡率。
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引用次数: 0
A Study of the Effect of Preoperative Vaginal Antiseptic on Occurrence of Postoperative Infection in Cesarean Section 术前阴道消毒对剖宫产术后感染发生影响的研究
Pub Date : 2022-08-01 DOI: 10.21608/ebwhj.2022.140071.1177
suzan el sharkawy, Mohamed Amin, A. Mansy
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引用次数: 0
Early versus delayed removal of urinary catheter after Pelvic organ prolapse surgery and vaginal hysterectomy: A systematic review and meta-analysis of randomized controlled trials 盆腔器官脱垂手术和阴道子宫切除术后早期与延迟拔除导尿管:随机对照试验的系统回顾和荟萃分析
Pub Date : 2022-05-24 DOI: 10.21608/ebwhj.2022.127684.1173
K. Hammam, A. Ali, Esraa Ayman, Shymaa Abdel Hamid, Hussien Seeda, S. Elsayed, Ahmad Tareq Anwar, Fatma Saad, A. Ali, M. Ramadan, A. Hussein
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引用次数: 0
Vaginal Misoprostol before Elective Caesarean Section for Preventing Neonatal Respiratory Morbidity 选择性剖宫产前阴道使用米索前列醇预防新生儿呼吸系统疾病
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2021.109258.1159
A. Hassan, N. Mahmoud, M. Elhawary
Background: Delivery by elective caesarean section at a gestational age of less than 39 weeks increases the risk of various respiratory morbidities in the newborn including respiratory distress syndrome. Prostaglandins are substances that have beneficial effects on the neonatal lungs as it promote surfactant secretion by inducing the catecholamine surge. However on clinical practice, the effectiveness of the antenatal prophylactic administration prostaglandin is still not clear. Aim: This study aimed to evaluate the efficacy of vaginal Misoprostol before ECS in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity. Materials and Methods: Study sample included 159 participants were randomly assigned into 2 groups: Group (A): misoprostol group who administered 1/2 tablet of Cytotec (R) 200 g one hour before elective caesarean section and Group (B): included women received no treatment before elective caesarean section . Results: A significant decrease in respiratory rate among the Misoprostol group and decrease in neonatal respiratory morbidity especially RDS type 2, 3 and TTN, also misoprostol causes significant decrease in the rate of NICU admissions and none of the neonates required mechanical ventilation. Conclusion: Prophylactic misoprostol before elective caesarean at a gestational age of less than 39 weeks reduces the rate of neonatal respiratory morbidity and may prevent neonatal RDS type 2 and 3.
背景:胎龄小于39周的选择性剖宫产会增加新生儿各种呼吸系统疾病的风险,包括呼吸窘迫综合征。前列腺素是一种对新生儿肺部有益的物质,它通过诱导儿茶酚胺激增来促进表面活性剂的分泌。但在临床实践中,产前预防性给药前列腺素的有效性尚不明确。目的:本研究旨在评价胎龄小于38周的孕妇ECS前阴道应用米索前列醇预防新生儿呼吸系统疾病发生的效果。材料与方法:研究样本159例,随机分为两组:A组:米索前列醇组,择期剖宫产前1 h给予1/2片Cytotec (R) 200 g; B组:择期剖宫产前未接受任何治疗的妇女。结果:米索前列醇组呼吸频率显著降低,新生儿呼吸系统发病率显著降低,尤其是RDS 2型、3型和TTN,米索前列醇组新生儿NICU入院率显著降低,无新生儿需要机械通气。结论:胎龄小于39周的择期剖宫产前预防性使用米索前列醇可降低新生儿呼吸系统发病率,并可预防新生儿RDS 2型和3型。
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引用次数: 0
Value of 3D Ultrasonographic Assessment of Placental Volume and Perfusion Indices in The First Trimester As Predictors to The Occurrence of Preeclampsia 三维超声评估妊娠早期胎盘容量及血流灌注指标对先兆子痫发生的预测价值
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2022.117548.1166
Shaemaa Belal, Manal Alsayed, Hany Abdel Hamid, Ashraf ElBaz
Aim: The purpose of this study is to determine placental volume and vascular flow indices during the first trimester and their values as predictors of developing preeclampsia. Materials and Methods: A prospective analysis for standard antenatal follow up at 11 to 13 weeks of gestation was performed on 177 singleton pregnant women visiting the antenatal care outpatient clinic at Al-Sahel Teaching Hospital between June 2018 and June 2019. Transabdominal 3D ultrasonography ('placental biopsy') to determine placental volume and power Doppler assessment of placental vascularization were done for all cases. Results: Comparative analysis of placental volumes between the normal pregnancy and preeclamptic pregnancies groups revealed a statistically high significant difference ( P value < 0.001 ). The mean volume in the two groups was 84.9 ± 22 and 45.6 ± 11.4 cm3, respectively. In the normal pregnancy group, the volume of placenta was larger than preeclamptic pregnancies group. Also, comparative analysis of placental vascularization index (VI), flow index (FI), and vascularization flow index (VFI) between the normal pregnancy group and pregnancies group that developed preeclampsia revealed a statistically high significant difference ( P value <0.001 ). The mean values of (VI), (FI), and (VFI) in the two groups were (24.7±8.1, 95.4±9.1, 13.1±3. 7) and (16.2±5.8, 54.6±10.9, 8.1±2.1) respectively. Conclusion: Quantitative assessment of placental volume and vasculature using 3D power doppler VOCAL TM techniques can be used in the 1st trimester to predict preeclampsia. Placentas of pregnancy complicated with preeclampsia have smaller volume, fewer blood vessels (reduced VI) and decreased blood flow (reduced FI).
目的:本研究的目的是确定妊娠早期胎盘体积和血管流量指数及其作为先兆子痫发生的预测指标的价值。材料与方法:对2018年6月至2019年6月在Al-Sahel教学医院产前保健门诊就诊的177名单胎孕妇进行妊娠11 ~ 13周标准产前随访的前瞻性分析。所有病例均行经腹3D超声检查(“胎盘活检”)以确定胎盘体积,并对胎盘血管化进行功率多普勒评估。结果:正常妊娠组与子痫前期妊娠组胎盘体积比较,差异有统计学意义(P值< 0.001)。两组平均体积分别为84.9±22 cm3和45.6±11.4 cm3。正常妊娠组胎盘体积大于子痫前期妊娠组。正常妊娠组与子痫前期妊娠组胎盘血管形成指数(VI)、血流指数(FI)、血管形成流量指数(VFI)比较,差异有统计学意义(P值<0.001)。两组患者(VI)、(FI)、(VFI)均值分别为(24.7±8.1、95.4±9.1、13.1±3。7)和(16.2±5.8,54.6±10.9,8.1±2.1)。结论:三维功率多普勒VOCAL TM技术定量评估胎盘体积和血管可用于妊娠早期子痫前期的预测。妊娠合并子痫前期胎盘体积变小,血管减少(VI降低),血流减少(FI降低)。
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引用次数: 0
Comparison Between Letrozole With and Without Gonadotropins Injection on Pregnancy Rates in Infertile PCOS Patients : A Multicenter Randomized Observational Trial 来曲唑加与不加促性腺激素注射对不孕症多囊卵巢综合征患者妊娠率的比较:一项多中心随机观察试验
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2021.113640.1164
H. Ashry, T. Aly, A. Ragab
Background: We developed a multicenter randomized observational trial to assess the effectiveness of letrozole monotherapy and the co-therapy of letrozole and gonadotropins on pregnancy outcomes including the ovulation induction, pregnancy rate, estradiol (E2) levels and endometrial thickness in infertile women with polycystic ovarian syndrome (PCOS). Materials and Methods: At three in vitro fertilization (IVF) centers in Egypt, we conducted our study since May 2019 until we have recruited the planned number of patients. Infertile PCOS patients were recruited after they met our criteria. We had two intervention groups based on the treatment regimen. Moreover, baseline parameters, outcomes, and hormonal assessment were conducted throughout the study period. Results: We included 90 patients in this study and were equally randomized into two groups; the letrozole monotherapy (Group A) and the letrozole with gonadotropins (Group B) groups. The mean age was significantly higher in group A [26 (±3.5)] than group B [24.2 (±3.1)] ( P= 0.015 ). Both groups showed resulted in similar pregnancy rates (31.1%) ( P= 0.079 ). Moreover, group B [2.4 (±0.8)] resulted in a significantly higher ( P= 0.023 ) mean number of follicles than group A [2.0 (±0.7)]. On the other hand, no statistical significance was estimated in terms of estradiol levels and endometrial thickness ( P= 0.209 and 0.485, respectively). Conclusion: We concluded that letrozole monotherapy and in combination with gonadotropins obtain better pregnancy rates in PCOS patients. Moreover, the combination may be useful in reducing gonadotropin adverse events with the same acceptable rates.
背景:我们开展了一项多中心随机观察性试验,以评估来曲唑单药治疗和来曲唑与促性腺激素联合治疗对不孕多囊卵巢综合征(PCOS)妇女妊娠结局的影响,包括促排卵、妊娠率、雌二醇(E2)水平和子宫内膜厚度。材料和方法:自2019年5月起,我们在埃及的三个体外受精(IVF)中心进行了这项研究,直到我们招募了计划数量的患者。不孕症多囊卵巢综合征患者在符合我们的标准后被招募。根据治疗方案,我们有两个干预组。此外,在整个研究期间进行基线参数、结果和激素评估。结果:本研究纳入90例患者,随机分为两组;来曲唑单药组(A组)和来曲唑联合促性腺激素组(B组)。A组患者平均年龄[26(±3.5)岁]明显高于B组[24.2(±3.1)岁](P= 0.015)。两组妊娠率相近(31.1%)(P= 0.079)。B组[2.4(±0.8)个]平均卵泡数显著高于a组[2.0(±0.7)个](P= 0.023)。雌二醇水平与子宫内膜厚度差异无统计学意义(P分别为0.209、0.485)。结论:来曲唑单药治疗及与促性腺激素联合治疗可提高PCOS患者的妊娠率。此外,联合用药可能有助于减少促性腺激素不良事件的发生率相同。
{"title":"Comparison Between Letrozole With and Without Gonadotropins Injection on Pregnancy Rates in Infertile PCOS Patients : A Multicenter Randomized Observational Trial","authors":"H. Ashry, T. Aly, A. Ragab","doi":"10.21608/ebwhj.2021.113640.1164","DOIUrl":"https://doi.org/10.21608/ebwhj.2021.113640.1164","url":null,"abstract":"Background: We developed a multicenter randomized observational trial to assess the effectiveness of letrozole monotherapy and the co-therapy of letrozole and gonadotropins on pregnancy outcomes including the ovulation induction, pregnancy rate, estradiol (E2) levels and endometrial thickness in infertile women with polycystic ovarian syndrome (PCOS). Materials and Methods: At three in vitro fertilization (IVF) centers in Egypt, we conducted our study since May 2019 until we have recruited the planned number of patients. Infertile PCOS patients were recruited after they met our criteria. We had two intervention groups based on the treatment regimen. Moreover, baseline parameters, outcomes, and hormonal assessment were conducted throughout the study period. Results: We included 90 patients in this study and were equally randomized into two groups; the letrozole monotherapy (Group A) and the letrozole with gonadotropins (Group B) groups. The mean age was significantly higher in group A [26 (±3.5)] than group B [24.2 (±3.1)] ( P= 0.015 ). Both groups showed resulted in similar pregnancy rates (31.1%) ( P= 0.079 ). Moreover, group B [2.4 (±0.8)] resulted in a significantly higher ( P= 0.023 ) mean number of follicles than group A [2.0 (±0.7)]. On the other hand, no statistical significance was estimated in terms of estradiol levels and endometrial thickness ( P= 0.209 and 0.485, respectively). Conclusion: We concluded that letrozole monotherapy and in combination with gonadotropins obtain better pregnancy rates in PCOS patients. Moreover, the combination may be useful in reducing gonadotropin adverse events with the same acceptable rates.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81196365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Thalamic Echogenicity by Ultrasound Be Used as a Predictor of Fetal Lung Maturity? 超声丘脑回声能作为胎儿肺成熟度的预测指标吗?
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2022.126327.1168
Mohamed Elsafty, Sherif Abdel Khalek, A. Farid, Haitham Gad Elkarem
Aim: The present study aimed to evaluate using thalamic echogenicity by ultrasound as a predictor of fetal lung maturity in comparison with other ultrasound markers. Methods: This was a prospective study performed in Ain shams Maternity Hospital, Cairo, Egypt from August, 2020 until April 2021. Two hundred and thirty-eight pregnant women (36 to 40 weeks of gestation) who were admitted for elective cesarean section were recruited. An obstetric ultrasound scan was done at the same day of their elective cesarean section to evaluate echogenicity of the thalamus, to measure presence of ossification centers of distal femur epiphysis (DFE) and proximal tibia epiphysis (PTE), to measure biparietal diameter, to detect placental changes and amniotic fluid vernix. The outcome measures were APGAR scores at 1 minute and 5 minutes, admission to neonatal intensive care unit, duration of hospitalization and signs of respiratory distress syndrome (RDS). Results: The presence of echogenic thalamus as a sign of fetal lung maturity had a specificity of 77.2% which was lower than specificity of presence of PTE (90.4%) and measurement of BPD (82.6%). Diagnostic accuracy was 77.3% which was also lower than PTE (90.8%) and BPD (81.5%), respectively. Sensitivity was 78.9% which was lower than PTE (99.5%) and BPD (82.6%), respectively. Negative predictive value for thalamic echogenicity, PTE and DFE were 97.7%, 99.5% and 99.2%, respectively. Conclusion: Evaluation of echogenic thalamus could be an accurate method to predict fetal lung maturity. However, further studies are required to strengthen such idea.
目的:本研究旨在通过与其他超声指标的比较,评价丘脑回声强度作为胎儿肺成熟度的预测指标。方法:这是一项前瞻性研究,于2020年8月至2021年4月在埃及开罗的Ain shams妇产医院进行。我们招募了238名接受选择性剖宫产的孕妇(妊娠36至40周)。在选择性剖宫产的同一天进行产科超声扫描,以评估丘脑的回声性,测量股骨远端骨骺(DFE)和胫骨近端骨骺(PTE)骨化中心的存在,测量双顶骨直径,检测胎盘变化和羊水积水。结局指标为1分钟和5分钟时的APGAR评分、新生儿重症监护病房入院情况、住院时间和呼吸窘迫综合征(RDS)体征。结果:回声丘脑作为胎儿肺成熟标志的特异性为77.2%,低于PTE存在(90.4%)和BPD测量(82.6%)的特异性。诊断正确率为77.3%,低于PTE(90.8%)和BPD(81.5%)。敏感性为78.9%,分别低于PTE(99.5%)和BPD(82.6%)。丘脑回声性、PTE和DFE的阴性预测值分别为97.7%、99.5%和99.2%。结论:丘脑回声评价是预测胎儿肺成熟度的准确方法。然而,需要进一步的研究来加强这一观点。
{"title":"Can Thalamic Echogenicity by Ultrasound Be Used as a Predictor of Fetal Lung Maturity?","authors":"Mohamed Elsafty, Sherif Abdel Khalek, A. Farid, Haitham Gad Elkarem","doi":"10.21608/ebwhj.2022.126327.1168","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.126327.1168","url":null,"abstract":"Aim: The present study aimed to evaluate using thalamic echogenicity by ultrasound as a predictor of fetal lung maturity in comparison with other ultrasound markers. Methods: This was a prospective study performed in Ain shams Maternity Hospital, Cairo, Egypt from August, 2020 until April 2021. Two hundred and thirty-eight pregnant women (36 to 40 weeks of gestation) who were admitted for elective cesarean section were recruited. An obstetric ultrasound scan was done at the same day of their elective cesarean section to evaluate echogenicity of the thalamus, to measure presence of ossification centers of distal femur epiphysis (DFE) and proximal tibia epiphysis (PTE), to measure biparietal diameter, to detect placental changes and amniotic fluid vernix. The outcome measures were APGAR scores at 1 minute and 5 minutes, admission to neonatal intensive care unit, duration of hospitalization and signs of respiratory distress syndrome (RDS). Results: The presence of echogenic thalamus as a sign of fetal lung maturity had a specificity of 77.2% which was lower than specificity of presence of PTE (90.4%) and measurement of BPD (82.6%). Diagnostic accuracy was 77.3% which was also lower than PTE (90.8%) and BPD (81.5%), respectively. Sensitivity was 78.9% which was lower than PTE (99.5%) and BPD (82.6%), respectively. Negative predictive value for thalamic echogenicity, PTE and DFE were 97.7%, 99.5% and 99.2%, respectively. Conclusion: Evaluation of echogenic thalamus could be an accurate method to predict fetal lung maturity. However, further studies are required to strengthen such idea.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80144297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Effect of Rectus Muscle Re-Approximation by Two Techniques Versus Non Re-Approximation During Caesarean Section on Postoperative Pain: A Randomized Controlled Trial 评估剖宫产术中两种方法重新逼近直肌与非重新逼近直肌对术后疼痛的影响:一项随机对照试验
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2022.107310.1158
Ahmed Mohamed, A. Ahmed, Ali H. Yosef, Diaa Eldeen Abd El Aal El Nashar
Aim: To assess the effect of rectus muscle re-approximation by two different techniques during Cesarean Section on postoperative pain. Study Design: A prospective, single-blinded, randomized clinical trial. Patients and Methods: It included (n=156) primigravida who underwent Cesarean section. They were randomly allocated into three groups; Group (A): non-closure of rectus muscle, Group (B): re-approximation by three simple interrupted sutures, and Group (C) re-approximation by three vertical mattress sutures. Postoperative pain was assessed by visual analogue scale during hospital stay. Postoperative analgesia, amount of blood loss and occurrence of postoperative complications were also investigated. Results: Women with non-closure technique had significantly lower visual analogue score (VAS) at the end of 1 st 48 hours postoperative (2.86 ± 1.61) in comparison to other groups. Women who underwent re-approximation either with simple interrupted sutures or vertical mattress sutures had no difference as regard VAS (4.26 ± 2.19 vs. 4.80 ± 2.36; P value = 0.19). Regarding to postoperative analgesia intake, women with non-re-approximation had significant lower intake of analgesic drugs (170.76 ± 30.85 mg) in comparison to other two groups. Both techniques of muscle closure showed no difference in analgesic requirements postoperative. Conclusion: Rectus muscle approximation is associated with significant increase in postoperative pain and analgesia.
目的:探讨剖宫产术中采用两种不同术式重新逼近直肌对术后疼痛的影响。研究设计:前瞻性、单盲、随机临床试验。患者和方法:包括(n=156)行剖宫产术的初产妇。他们被随机分为三组;(A)组:直肌不闭合,(B)组:三次简单间断缝线重新逼近,(C)组:三次垂直床垫缝线重新逼近。术后住院期间采用视觉模拟量表评估疼痛。观察术后镇痛、出血量及术后并发症发生情况。结果:术后1 ~ 48小时,行不闭合术的患者视觉模拟评分(VAS)明显低于其他组(2.86±1.61)。采用简单中断缝线或垂直床垫缝线进行重新近似的妇女在VAS方面没有差异(4.26±2.19∶4.80±2.36;P值= 0.19)。术后镇痛药物摄入方面,非重新近似组患者镇痛药物摄入明显低于其他两组(170.76±30.85 mg)。两种肌肉闭合技术在术后镇痛需求上没有差异。结论:直肌近似与术后疼痛和镇痛明显增加有关。
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引用次数: 0
The Efficacy of Third Trimester Cervical Length Measurement as A Predictor of Ante-Partum Haemorrhage Among Pregnancies Complicated with Placenta Previa 妊娠晚期宫颈长度测量作为妊娠合并前置胎盘产前出血预测指标的有效性
Pub Date : 2022-05-01 DOI: 10.21608/ebwhj.2022.127316.1169
M. Eid, R. Omar, Ahmed Mohamed, Khaled Abdel Maqsood
Aim: To estimate whether the cervical length and can be used as a method to predict peripartum complications as antepartum haemorrhage and preterm delivery in cases of complete placenta previa. Methods: Between October 2013 and April 2014, transvaginal measurement of cervical length was done for 30 cases of complete placenta previa identified between 28 weeks and 36 weeks of gestation. This was correlated to the clinical outcome of pregnancy with recordings for the gestational age at time of delivery, occurrence if any complications as antepartum haemorrhage ,blood transfusion, caesarean hysterectomy , preterm delivery and the need for NICU admission and whether the caesarean section was elective or emergency caesarean section was needed before 36 weeks due to massive haemorrhage. Results: Antepartum haemorrhage necessitating emergency cesarean section was observed in 17 patients (56.7%). This was the basis of grouping the patients into two outcome groups: Emergency CS group and elective delivery group. Using receiver-operating characteristic (ROC) curve analysis we found that a cervical length ≤ 33 mm at 28 weeks was predictive of antepartum haemorrhage necessitating emergency caesarean section with a sensitivity of 88.2% and specificity of 61.5% positive predictive value of 75.0% and negative predicative value of 80.0% and accuracy of 76.7%. Area under the curve (AUC) was 0.760. with P-value < 0.01 Conclusion: Short cervical length measurements at cut-off value ≤33mm may predict increased risk of hemorrhage and emergency caesarean section in patients with complete placenta previa.
目的:探讨宫颈长度是否可作为预测完全性前置胎盘患者产前出血、早产等围生期并发症的指标。方法:2013年10月~ 2014年4月,对30例妊娠28 ~ 36周的完全性前置胎盘患者进行经阴道宫颈长度测量。这与妊娠的临床结果相关,记录分娩时的胎龄,是否发生任何并发症,如产前出血、输血、剖腹产子宫切除术、早产和是否需要入住新生儿重症监护病房,以及剖腹产是选择性的还是在36周前因大出血而需要紧急剖腹产。结果:产前出血需紧急剖宫产17例(56.7%)。这是将患者分为两个结果组的基础:紧急CS组和选择性分娩组。通过受试者工作特征(ROC)曲线分析,我们发现28周宫颈长度≤33 mm预测产前出血需要紧急剖宫产的敏感性为88.2%,特异性为61.5%,阳性预测值为75.0%,阴性预测值为80.0%,准确率为76.7%。曲线下面积(AUC)为0.760。结论:截断值≤33mm的短宫颈长度测量可预测完全性前置胎盘患者出血及急诊剖宫产的风险增加。
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引用次数: 0
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Evidence Based Women's Health Journal
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