Pub Date : 2018-12-31DOI: 10.23937/IJTD-2017/1710009
S. Cavalcanti, V. Lerena, C. Gómez
{"title":"Acute Myopericarditis an Uncommon Presentation of Severe Leptospirosis - A Case Report and Literature Review","authors":"S. Cavalcanti, V. Lerena, C. Gómez","doi":"10.23937/IJTD-2017/1710009","DOIUrl":"https://doi.org/10.23937/IJTD-2017/1710009","url":null,"abstract":"","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"286 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122691604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-31DOI: 10.23937/IJTD-2017/1710004
J. Akinneye, Mm Fasidi, O. Afolabi, F. Adesina
{"title":"Prevalence of Urinary Schistosomiasis among Secondary School Students in Ifedore Local Government, Ondo State, Nigeria","authors":"J. Akinneye, Mm Fasidi, O. Afolabi, F. Adesina","doi":"10.23937/IJTD-2017/1710004","DOIUrl":"https://doi.org/10.23937/IJTD-2017/1710004","url":null,"abstract":"","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124338980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-31DOI: 10.23937/IJTD-2017/1710012
A. Carlos, A. Susana, A. Jose
Strongyloides stercoralis is a common nematode causing intestinal parasitosis in the Ecuadorian population, but cases of lung infection by this helminth have not been documented in Ecuador. We document the first case of pulmonary strongyloidias is caused by S. stercoralis filariform larvae in a male patient from Manabí Province (Ecuador), showing clinical symptoms of terminal pulmonary syndrome. Previous to the decease of the patient, the larvae were identified by the direct smear method of a fresh bronchial aspirate sample collected from the patient. Hyperinfection by filariform larvae (L3) was observed, exhibiting an abundance of up to four larvae per microscopic field. We suggest that an earlier treatment of the patient with a high spectrum anthelmintic could have saved his life. Pulmonary strongyloidiasis can be under diagnosed if the parasitological analysis of wet mounts of bronchial aspirate from patients suffering of chronic bronchitis and pulmonary syndrome to investigate the possible presence of S.stercoralis is not conducted. The training for microbiological screening using classic direct methods, as well as the constant investigation of this parasitosis and other helminthiases are still vital and relevant for public health personnel and microbiologists in developing countries in order to provide an early diagnosis of underdiagnosed parasitosis.
{"title":"Pulmonary Strongyloidiasis in a Patient with Terminal Pulmonary Syndrome in Manabi Province, Ecuador: A Report Case","authors":"A. Carlos, A. Susana, A. Jose","doi":"10.23937/IJTD-2017/1710012","DOIUrl":"https://doi.org/10.23937/IJTD-2017/1710012","url":null,"abstract":"Strongyloides stercoralis is a common nematode causing intestinal parasitosis in the Ecuadorian population, but cases of lung infection by this helminth have not been documented in Ecuador. We document the first case of pulmonary strongyloidias is caused by S. stercoralis filariform larvae in a male patient from Manabí Province (Ecuador), showing clinical symptoms of terminal pulmonary syndrome. Previous to the decease of the patient, the larvae were identified by the direct smear method of a fresh bronchial aspirate sample collected from the patient. Hyperinfection by filariform larvae (L3) was observed, exhibiting an abundance of up to four larvae per microscopic field. We suggest that an earlier treatment of the patient with a high spectrum anthelmintic could have saved his life. Pulmonary strongyloidiasis can be under diagnosed if the parasitological analysis of wet mounts of bronchial aspirate from patients suffering of chronic bronchitis and pulmonary syndrome to investigate the possible presence of S.stercoralis is not conducted. The training for microbiological screening using classic direct methods, as well as the constant investigation of this parasitosis and other helminthiases are still vital and relevant for public health personnel and microbiologists in developing countries in order to provide an early diagnosis of underdiagnosed parasitosis.","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116670889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-31DOI: 10.23937/IJTD-2017/1710007
M MossDelynn, T WhitneyMatthew, N ChardAnna, T. Victoria, D. Seydou, H GoodmanChristin, Bullard Stevan, E WiegandRyan, C FreemanMatthew, J LammiePatrick, Chang Gwong-Jen
{"title":"Development of Vaccination against Fungal Disease: A Review Article","authors":"Tesfahuneygn Gebrehiwet, Gebreegziabher Gebremichael","doi":"10.23937/ijtd-2017/1710005","DOIUrl":"https://doi.org/10.23937/ijtd-2017/1710005","url":null,"abstract":"","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130280384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2643-461x/1710074
Bordinhon Jessica Maria Oliveira, de Oliveira Renata Pinheiro cavallaro, Vidal Larissa Vaneska Izidorio, Cauti Samanta Bernardes, Monfardini Juliana Pasquini Ferraz, de Sousa Bruno Macedo, Gentil Thais Marques Sanches, Milani Marcus Vinícius Landim Stori, Martins Antonio Camargo
{"title":"Case Report: Bee Sting-Associated Meningitis due to S. aureus","authors":"Bordinhon Jessica Maria Oliveira, de Oliveira Renata Pinheiro cavallaro, Vidal Larissa Vaneska Izidorio, Cauti Samanta Bernardes, Monfardini Juliana Pasquini Ferraz, de Sousa Bruno Macedo, Gentil Thais Marques Sanches, Milani Marcus Vinícius Landim Stori, Martins Antonio Camargo","doi":"10.23937/2643-461x/1710074","DOIUrl":"https://doi.org/10.23937/2643-461x/1710074","url":null,"abstract":"","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126408785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2643-461x/1710073
A. Kumari, J. Vidanapathirana, J. Amarasekara, L. Karunanayake
{"title":"Educational Intervention Package to Increase Knowledge on Minimizing the Delays in Seeking Treatment of Leptospirosis in a District of Sri Lanka","authors":"A. Kumari, J. Vidanapathirana, J. Amarasekara, L. Karunanayake","doi":"10.23937/2643-461x/1710073","DOIUrl":"https://doi.org/10.23937/2643-461x/1710073","url":null,"abstract":"","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116685666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2643-461x/1710050
Vargas Julio Alberto Rojas, López América García, Vargas Aliesky Ramírez, Fidalgo Lianet Monzote, Froeyen Matheus
Leishmaniasis is a disease caused by the protozoan Leishmania that is considered one of the causes of death from parasitic infection worldwide. Looking for the right chemotherapy against leishmaniasis has been difficult because of the high toxicity of the most effective drugs. This disease is considered among the 13 unattended diseases worldwide according to the World Health Organization (WHO). In the present work, the leishmanicidal activity against L. amazonensis promastigote and cytotoxicity of 9 aryl-substituted imidazoles were evaluated. In vitro antileishmanial results indicated that the ligand 1, 2 and 7 exhibited strong activity against L. amazonensis promastigote, but only the compound 1 and 4 showed agood selectivity and cytotoxicity against the parasite. According to the results of the molecular docking, the aromatic substituents have mainly stabilizing hydrophobic interactions with the enzymatic matrix, which shows the probability that the protein trypanothione reductase is the therapeutic target of these compounds as possible antileishmanial drugs.
{"title":"In Vitro Evaluation and Molecular Docking Studies of Aryl-Substituted Imidazoles against Leishmania Amazonensis","authors":"Vargas Julio Alberto Rojas, López América García, Vargas Aliesky Ramírez, Fidalgo Lianet Monzote, Froeyen Matheus","doi":"10.23937/2643-461x/1710050","DOIUrl":"https://doi.org/10.23937/2643-461x/1710050","url":null,"abstract":"Leishmaniasis is a disease caused by the protozoan Leishmania that is considered one of the causes of death from parasitic infection worldwide. Looking for the right chemotherapy against leishmaniasis has been difficult because of the high toxicity of the most effective drugs. This disease is considered among the 13 unattended diseases worldwide according to the World Health Organization (WHO). In the present work, the leishmanicidal activity against L. amazonensis promastigote and cytotoxicity of 9 aryl-substituted imidazoles were evaluated. In vitro antileishmanial results indicated that the ligand 1, 2 and 7 exhibited strong activity against L. amazonensis promastigote, but only the compound 1 and 4 showed agood selectivity and cytotoxicity against the parasite. According to the results of the molecular docking, the aromatic substituents have mainly stabilizing hydrophobic interactions with the enzymatic matrix, which shows the probability that the protein trypanothione reductase is the therapeutic target of these compounds as possible antileishmanial drugs.","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129295147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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