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EPIDEMIO-CLINICAL PROFILE OF CERVICAL SPINE TRAUMA AT CHU-JRA MADAGASCAR 马达加斯加chu-jra地区颈椎外伤的流行病学-临床概况
Pub Date : 2019-08-04 DOI: 10.53555/eijmhs.v5i3.82
Bemora Joseph Synèse, Tojo Hery Tsitovah Rakotondrainibe, P. Rakotozanany, Willy Francis Rakotondraibe, W. Ratovondrainy, M. Rabarijaona, C. Andriamamonjy
The cervical spine trauma is a frequent and serious lesion involving not only the vital prognostic but also functional. The target of this work was to determinate the epidemiological clinical profile and the issue related to the management of cervical spine traumatism in Madagascar. It was the 3 years retrospective works with 41 cases of the cervical spine trauma hospitalized and supported in a department of neurosurgery and resuscitation at CHU-JRA Antananarivo Madagascar.  We included all patients’ records for traumatized cervical spine and incomplete files have been excluded. While the targeted period, 41 cases of the cervical spine trauma has been studied, 24, 39% of traumatized was between 21-30 years old with a clear male predominance of 80, 48% (sex ratio 4, 1).  The etiology is dominated by a fall and the majority was of domestic accident (46,34%). The cervical wounded was part of polytrauma, 58, 53 % of the case are brain injury.  Clinically, 39, 02% of the patients were tetraplegic and the standard radiograph represented the requested radiological tool in 82.92%. The mortality rate was 21, 95%. The cervical spine trauma remains pathology difficult to manage because of the respiratory risk which requires a managing in reanimation and the prognostic vital is reserved for complete quadriplegics. 
颈椎外伤是一种常见的严重病变,不仅影响预后,而且影响功能。这项工作的目的是确定马达加斯加颈椎损伤的流行病学临床概况和相关管理问题。这是对在马达加斯加塔那那利佛中央医院神经外科和复苏科住院治疗和支持的41例颈椎外伤患者3年的回顾性研究。我们纳入了所有颈椎外伤患者的记录,排除了不完整的档案。在研究的41例颈椎外伤病例中,21.39%的患者年龄在21-30岁之间,男性占明显优势,占80.48%(性别比4.1)。病因以跌倒为主,以家庭意外为主(46.34%)。颈部损伤是多发伤的一部分,其中58.3%为颅脑损伤。临床上,39.02%的患者为四肢瘫痪,82.92%的患者标准x线片符合要求。死亡率为21.95%。由于呼吸风险,颈椎创伤在病理学上仍然难以处理,需要在复苏时进行管理,而预后至关重要的是为完全四肢瘫痪保留的。
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引用次数: 0
REVIEW ARTICLE: THE ROLE OF DENDRITIC CELLS IN THE CONTROL ON INNATE IMMUNITY 综述文章:树突状细胞在先天免疫控制中的作用
Pub Date : 2019-07-06 DOI: 10.53555/eijmhs.v5i3.81
James D Yelima, S. A. Ufelle, A. Bukar, Dauda Madubu Milgwe, Oyeleke kikilemo Olayemi, Chidozie Kenechi Chikwendu
Dendritic cells play an important role in host immunity by inducing innate inflammatory responses to pathogens, efficiently priming immature T cells, activating memory T cells and promoting B cell activation. Dendritic cells are also integral in maintaining steady- state immune homeostasis by continually presenting tissue-derived selfantigens to CD4+ and CD8+ T cells in the absence of inflammatory signals, leading to tolerance against those self-antigens. The important of innate immunity lies not only in directly confronting pathogenic and non-pathogenic insults but also in instructing the development of an efficient adaptive immune response.
树突状细胞通过诱导对病原体的先天炎症反应、有效启动未成熟T细胞、激活记忆T细胞和促进B细胞激活,在宿主免疫中发挥重要作用。树突状细胞在没有炎症信号的情况下,通过持续向CD4+和CD8+ T细胞呈递组织来源的自身抗原,导致对这些自身抗原的耐受性,在维持稳态免疫稳态中也是不可或缺的。先天免疫的重要作用不仅在于直接对抗致病性和非致病性损伤,而且还在于指导有效的适应性免疫反应的发展。
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引用次数: 0
THE PUBLIC HEALTH IMPLICATION OF CONSUMING SURFACE WATER IN CONTAMINATED SITES, IN AKAMKPA LOCAL GOVERNMENT AREA, CROSS RIVER STATE. 在克罗斯河州akamkpa地方政府区受污染地点饮用地表水对公众健康的影响。
Pub Date : 2019-07-02 DOI: 10.53555/eijmhs.v5i3.79
O. E. Eteng, I. Arikpo, V. Ekam, G. Ekpo, J. Enobong, K. Abam, Savour Ufot., E. Ubana
Heavy metals and other municipal waste in addition to anthropogenic activities have been observed in surface streams.  Since humans consume water every day, it became imperative to evaluate the physicochemical parameters of water and heavy metals concentration in surface streams towards documenting the water quality and streams at Camp2 village, Akamkpa Local Government Area, Cross River State. Methodology: Sample collection bottles were used as specie materials which are really cleaned with substance, cleaned with liquid accompanied by real liquid previous placing in 5%HNO3 for over 24hours. Liquid species were gathered from the surface water bodies by simply scooping. Using plastic bowels into 5litre acid washed polypropylene containers. Samples were collected in two study site, the samples were analyzed for various heavy metals and physicochemical parameters i.e. pH, D.O, Temp, Electrical Conductivity, Total dissolved oxygen, Turbidity, and Total hardness by using standard methods and procedures while heavy metals such Ni, Cd, pb, Hg, As, were also analyzed using Atomic Absorption Spectrophotometer (AAS).  Results: The physicochemical parameters and heavy metals shows that all the parameters analyzed fell below WHO (2010) Standards for drinking water except for temperature and total hardness which are significantly(P<0.05) within WHO Standards (2010). Also, the results of the heavy metals concentration were above permissibility limits. Hence, these values were above WHO standard (0.1mg/l) and FAO/WHO standards of (0.2mg/kg) while others were within joint FAO/WHO standard limit.  Conclusion: Contamination of surface streams in the community has threating both humans’ health and animals including water quality. Therefore, the introduction of physical and chemical heavy metal remediation is required to protect our surface streams within the Environment.
除人为活动外,在地表溪流中还观察到重金属和其他城市废物。由于人类每天都要用水,因此有必要评估水的物理化学参数和地表溪流中的重金属浓度,以记录克Cross River州Akamkpa地方政府区Camp2村的水质和溪流。方法:样品采集瓶作为试样,用真物清洗,用真液清洗,用真液清洗后置于5%HNO3中放置24小时以上。通过简单的舀取从地表水体中收集液体种类。将塑料肠子放入5升的酸洗聚丙烯容器中。在两个研究地点采集样品,采用标准的方法和程序对样品进行了各种重金属和理化参数(pH、D.O、温度、电导率、总溶解氧、浊度、总硬度)的分析,并采用原子吸收分光光度计(AAS)对Ni、Cd、pb、Hg、As等重金属进行了分析。结果:理化指标和重金属指标均低于世界卫生组织(2010)饮用水标准,除温度和总硬度低于世界卫生组织(2010)标准显著(P<0.05)外。此外,重金属浓度检测结果均高于允许限值。因此,这些值高于WHO标准(0.1mg/l)和FAO/WHO标准(0.2mg/kg),而其他值在FAO/WHO联合标准范围内。结论:社区地表水的污染对人的健康和动物的水质都构成了威胁。因此,引入物理和化学重金属修复是必要的,以保护我们的环境中的地表溪流。
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引用次数: 0
DETERMINANTS OF ADHERENCE TO GUIDELINES TO EXCLUSIVE BREAST FEEDING AMONG MOTHERS OF INFANTS AGED 0 – 6 MONTHS ATTENDING MCH CLINIC AT KISUMU COUNTY HOSPITAL 在基苏木县医院妇幼保健诊所就诊的0 - 6个月婴儿的母亲遵守纯母乳喂养指南的决定因素
Pub Date : 2019-07-02 DOI: 10.53555/eijmhs.v5i3.80
S. K. Njeru
Background: Exclusive Breast Feeding of a child remains the best and safest source of nutrition for the vast majority of infants worldwide. However, this recommended practice is hardly adopted by many mothers as no more than 30% of infants are exclusively breastfed globally. Objective: To determine the factors influencing adherence to EBF among mothers of infants aged 0-6 months attending Maternal Child Health Clinic (MCH) in Kisumu County Hospital Design: A descriptive cross-sectional study Study Setting: Maternal Child Health Clinic (MCH) at Kisumu County Hospital. Study Subjects: All mothers of infants aged 0-6 months and receiving health care services in the MCH clinic at Kisumu County Hospital. Results: Sixty-four per cent (64%) of the respondents agreed that pre-lacteal feeds should be commenced as soon a baby is born, 69% of the respondents stated that the number of children a mother has could influence adherence to exclusive breast feeding and 73% stated that infants should be given mixture of feeds during the course of breastfeeding. Conclusion: Demographic factors such as age of the mother, marital status, level of education and number of children a mother has influences the adherence to exclusive breast feeding.
背景:对全世界绝大多数婴儿来说,纯母乳喂养仍然是最好和最安全的营养来源。然而,这一建议的做法几乎没有被许多母亲采用,因为全球纯母乳喂养的婴儿不超过30%。目的:探讨在基苏木县医院妇幼保健诊所(MCH)就诊的0-6个月婴儿母亲对EBF依从性的影响因素。设计:描述性横断面研究。研究环境:基苏木县医院妇幼保健诊所(MCH)。研究对象:在基苏木县医院妇幼保健诊所接受保健服务的0-6个月婴儿的所有母亲。结果:64%(64%)的答复者同意婴儿一出生就应开始乳前喂养,69%的答复者说,母亲的子女数量可能影响对纯母乳喂养的坚持,73%的答复者说,婴儿在母乳喂养过程中应给予混合喂养。结论:母亲年龄、婚姻状况、受教育程度、子女数量等人口因素对坚持纯母乳喂养有影响。
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引用次数: 0
TREND AND PROJECTION OF MODERN CONTRACEPTIVE PREVALENCE RATE IN INDIA FOR FP2020 COMMITMENT 印度现代避孕普及率的趋势和预测,以实现fp2020承诺
Pub Date : 2019-06-10 DOI: 10.53555/eijmhs.v5i2.78
Abhishek Kumar, R. Dhakad
Introduction: Worldwide, India was the first country to introduce a National Programme for Family Planning in 1952. Following its memorable inception, the Family Planning project has experienced numerous changes as far as approach and real program usage. Now India has committed in the London summit 2012 for family planning programme or interventions. Family planning programme or interventions will be performed as the main component of Universal Health Coverage. It will be achieved through the largest public health programme in the world, the National Rural Health Mission (NRHM) and as well as National Urban Health Mission (NUHM). And also, India is focusing on SDG, by 2030, ensure universal access to sexual and reproductive health-care services, including for family planning, information and education, and the integration of reproductive health into national strategies and programmes, as imitated in Sustainable Development Goal 3.7. Objective: First objective is to analyses the current trend of mCPR and project it for FP2020 and second to analyze the increase in the number of users under FP2020 as per the commitment to increase additional 48 million users. Materials & Method: We performed a secondary analysis on the data given by FP2020’s website. Which provides us information and resources on the global partnership designed for everyone working to advance access to modern contraceptives for all girls and women who want them. Result and conclusion: The result has estimated that the mCPR will rise to 55 percent in 2020 from 53 of 2012. But if we want to achieve the target of 175.39 (127 million users till 2012 and additional user of 48 million till 2020, which comes out to be 175 million) then we will have to increase the mCPR to 68 percent. Then only we will be able to achieve that. Otherwise the target looks unrealistic to achieve. 
导言:在世界范围内,印度是第一个在1952年实行国家计划生育方案的国家。在其令人难忘的开始之后,计划生育项目在方法和实际程序使用方面经历了许多变化。现在,印度在2012年伦敦峰会上承诺实施计划生育方案或干预措施。计划生育方案或干预措施将作为全民健康覆盖的主要组成部分实施。这一目标将通过世界上最大的公共卫生方案,即国家农村保健团和国家城市保健团来实现。此外,印度正在重点关注可持续发展目标,即到2030年确保普及性保健和生殖保健服务,包括计划生育、信息和教育服务,并按照可持续发展目标3.7的做法,将生殖保健纳入国家战略和方案。目标:第一个目标是分析当前mCPR的趋势,并为FP2020进行预测;第二个目标是分析FP2020下用户数量的增加,按照增加4800万用户的承诺。材料与方法:我们对FP2020网站提供的数据进行了二次分析。它为我们提供了关于全球伙伴关系的信息和资源,旨在为所有努力促进所有需要现代避孕药具的女孩和妇女提供避孕药具的人。结果和结论:结果估计mCPR将从2012年的53%上升到2020年的55%。但如果我们想要实现17539的目标(到2012年有1.27亿用户,到2020年增加4800万用户,即1.75亿),那么我们就必须将mCPR提高到68%。只有这样,我们才能实现这一目标。否则,这个目标看起来不现实。
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引用次数: 0
COMPUTER-ASSISTED 'PROBACENT' FORMULAS PREDICTING TOLERANCE OF MICE TO METRAZOL AND ELECTROSHOCK: USE OF APPLE COMPUTER WITH CALCLINE PROGRAM AND METHOD TO CONSTRUCT 计算机辅助预测小鼠对美曲唑和电击耐受的“概率”公式:用苹果计算机与calcline程序和方法构建
Pub Date : 2019-06-08 DOI: 10.53555/eijmhs.v5i2.77
Sung Jang Chung
 Calcline computer program is applied to construct the author's 'probacent' formulas with use of Apple computer, MacBook that express the mathematical relationship among the drug dose of Metrazol, the time after administration and the percentage of mortality or among the voltage of electroshock, the duration and the percentage of occurrence of convulsion in mice. Analysis of the actual and the computer-assisted predicted mortality or percentage of occurrence of convulsion in mice has shown a remarkable agreement and a fair accuracy (p>0.995 in chi square goodness-of-fit test). The method how to construct the 'probacent' formula in biomedical research is described in detail in this study.
应用Calcline计算机程序,利用苹果电脑MacBook构建作者的“概率”公式,表达了美曲唑给药剂量、给药时间与小鼠死亡率百分比之间或电击电压、持续时间与小鼠惊厥发生率百分比之间的数学关系。对小鼠的实际死亡率和计算机辅助预测的惊厥发生率进行分析,显示出显著的一致性和相当的准确性(卡方拟合优度检验p>0.995)。本文详细介绍了生物医学研究中“概率”公式的构造方法。
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引用次数: 0
PLACE OF ORTHOPEDIC TREATMENT OF DIAPHYSEAL FRACTURES OF THE UNCOMPLICATED HUMERUS IN A PRECARIOUS ENVIRONMENT 不稳定环境下简易肱骨骨干骨折的骨科治疗
Pub Date : 2019-06-06 DOI: 10.53555/eijmhs.v5i2.76
Tata Tjf
Introduction: In Madagascar, the management of diaphyseal fractures of the humerus is essentially orthopedic, the functional result is difficult to evaluate because little study has been done. Methods: We performed a prospective, single-center study of patients presenting with a diaphyseal fracture of the uncomplicated humerus treated orthopedically with CHUJRA from December 12th, 2015 to March 31st, 2017 and then reviewed at 6 months of follow-up for the functional evaluation. Results: Twenty-seven cases were collected (2.16%). The average age was 38 years old. The sex ratio was 3.5. The road accident was the most common (63% of cases). 16 out of 27 cases were of type a, 6 of type B and 5 of type C. Eighty-eight percent of fractures were consolidated before the 17th week of management. No pseudarthrosis was encountered. At 6 months of follow-up, the functional score according to the modified Stewart and Hundley score was very good in 03 cases, good in 15 cases, 6 cases of good enough and 3 cases of poor results. Conclusion: The diaphyseal fracture of the humerus is frequent and often secondary to a road accident in Madagascar. Orthopedic treatment not only allows for a high rate of consolidation but also a satisfactory functional recovery.
简介:在马达加斯加,肱骨骨干骨折的治疗基本上是矫形治疗,由于研究很少,因此很难评估其功能结果。方法:我们对2015年12月12日至2017年3月31日接受CHUJRA矫治的非复杂性肱骨骨干骨折患者进行了一项前瞻性、单中心研究,并在随访6个月时进行功能评估。结果:共收集病例27例(2.16%)。平均年龄为38岁。性别比为3.5。道路交通事故是最常见的(占63%)。a型16例,B型6例,c型5例,治疗17周前骨折愈合率88%。未见假关节。随访6个月时,改良Stewart和Hundley评分功能评分非常好03例,良好15例,一般6例,较差3例。结论:在马达加斯加,肱骨骨干骨折是一种常见的继发于交通事故的骨折。矫形治疗不仅允许高巩固率,而且令人满意的功能恢复。
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引用次数: 0
MINDFULNESS INTERVENTIONS AND SLEEP DISTURBANCE: A MINI REVIEW 正念干预和睡眠障碍:一个小回顾
Pub Date : 2019-06-04 DOI: 10.53555/eijmhs.v5i2.75
A. Tacón
Background: Sleep disturbance is a growing medical and public health concern with insomnia increasing worldwide. In addition to exacerbating health problems, insomnia may increase psychological vulnerability and proneness to accidents this is a mini narrative review as to the evidence regarding the efficacy of mindfulness-based interventions in the treatment of sleep disturbances such as insomnia in clinical populations.  Method: A search of medical, health, and psychological databases was conducted for mindfulnessbased therapies and intervention variants thereof in the treatment of terms that included: mindfulness-based interventions, mindfulness-based stress reduction (MBSR), mindfulness therapies or treatments AND sleep disturbance, insomnia, poor sleep quality, or sleep disorder.  Results: Standard protocol mindfulness-based stress reduction (MBSR) interventions and the specific mindfulness-based therapy for insomnia (MBT-I) have been investigated as potential nonpharmacologic treatments for insomnia and sleep disturbance in clinical populations. Additionally, randomized controlled clinical trials have been conducted in this area to determine efficacy of such mindfulness treatment strategies. Conclusion: Accumulating data indicate that mindfulness treatment protocols produce significant sleep outcome benefits with long-term follow-up duration.
背景:随着世界范围内失眠症的增加,睡眠障碍是一个日益受到关注的医学和公共卫生问题。除了加剧健康问题外,失眠还可能增加心理脆弱性和发生事故的可能性。这是一篇关于临床人群中以正念为基础的干预措施在治疗睡眠障碍(如失眠)方面有效性的证据的小型叙述性综述。方法:在医学、健康和心理学数据库中搜索基于正念的疗法及其干预变体,其中包括:基于正念的干预、基于正念的减压(MBSR)、正念疗法或治疗与睡眠障碍、失眠、睡眠质量差或睡眠障碍。结果:在临床人群中,正念减压(MBSR)干预的标准方案和特定的失眠正念疗法(MBT-I)作为潜在的失眠和睡眠障碍的非药物治疗方法进行了研究。此外,在这一领域进行了随机对照临床试验,以确定这种正念治疗策略的有效性。结论:越来越多的数据表明,正念治疗方案在长期随访期间具有显著的睡眠效果。
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引用次数: 0
ON THE COMPUTER COMPUTATION OF THE 'PROBACENT'-PROBABILITY EQUATION APPLICABLE TO BIOMEDICAL-PHENOMENA RESEARCH: A REVIEW OF THE 'PROBACENT' FORMULA 应用于生物医学现象研究的“概率”-概率方程的计算机计算:对“概率”公式的回顾
Pub Date : 2019-06-02 DOI: 10.53555/eijmhs.v5i2.74
Sung Jang Chung
 Marked variations are generally found in percentages of response occurring in human subjects and other living organisms exposed to external stressors, depending upon intensity of stressor, duration of exposure and individual sensitivity in biological phenomena. A clear and exact quantitative mathematical relationship among these three factors namely, intensity of stressor, duration of exposure and percentage of occurrence of response in biological phenomena such as human tolerance to total body irradiation is not known. The author proposed a general mathematical formula of 'probacent'-probability equation on the basis of results from animal experiments, clinical data reported in the literature, and theoretical reasoning that approximately expresses the relationship among the three factors. For calculation of the 'probacent'-probability equation, UBASIC program was primarily used in researches in various biomedical phenomena, employing Compaq Presario Windows 95 during a period of 23 years from 1995 to 2017. In this study, a possibility of use of Apple computer (OS-X) for mathematical calculation of the 'probacent'-probability equation was examined.  Calcline and UBASIC programs were applied to computer computation of the author's previous publication, " Computer-assisted formulas predicting radiation-exposure-induced-cancer risk in interplanetary travelers: Radiation safety for astronauts in space flight to Mars" and compared with regard to accuracy and applicability in computer computation. Calcline program is found to be usable in place of UBASIC on Apple computer, MacBook. Similarity and difference between Calcline and UBASIC are presented.
在暴露于外部压力源的人类受试者和其他生物体中,根据压力源的强度、暴露的持续时间和个体对生物现象的敏感性,通常发现发生反应的百分比有显著差异。这三个因素,即应激源强度、暴露时间和生物现象(如人体对全身辐照的耐受性)中反应发生的百分比之间的明确和精确的定量数学关系尚不清楚。作者根据动物实验结果、文献报道的临床数据和理论推理,提出了一个大致表达这三个因素之间关系的“概率”-概率方程的通用数学公式。对于“概率”-概率方程的计算,UBASIC程序主要用于各种生物医学现象的研究,使用康柏Presario Windows 95,时间为1995年至2017年的23年。在本研究中,研究了使用苹果电脑(OS-X)进行“概率”-概率方程数学计算的可能性。将Calcline和UBASIC程序应用于作者之前发表的《星际旅行者辐射暴露致癌风险的计算机辅助公式预测:飞往火星的宇航员的辐射安全》的计算机计算,并比较其在计算机计算中的准确性和适用性。Calcline程序被发现可以在苹果电脑MacBook上代替UBASIC。介绍了Calcline与UBASIC的异同。
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引用次数: 0
RELIGIOUS CONSIDERATIONS AS AN INTEGRAL PART IN MEDICAL DECISION-MAKING 宗教考虑是医疗决策的一个组成部分
Pub Date : 2019-05-14 DOI: 10.53555/eijmhs.v5i2.73
Saleh Alnahdi PhD
As a Muslim, I have a certain belief system that encompasses all of life, including my approach to medical ethics. My belief system is distinctive, as are others. Thus, the approaches of Judaism and Roman Catholicism offer a new perspective on medical ethics. The thesis of this paper is that religious considerations play a large and integral part in medical decision-making. The topics to be discussed include shared values; methodology, along with the related concepts of metaethics and the principle of double effect; and applications of these perspectives in medical ethics, particularly with regard to healthcare decisions involving the end of life. Each area will be explored in this paper in order to give insight into how these religious approaches came to be what they are today and how they present positions in medical ethics which may be at odds with other perspectives not based on any theological doctrines. Specifically, this paper discusses shared values, by referring to human dignity and its concepts, as well as theological principles in health care ethics, and definitions of these principles. In addition, the paper discusses the methodology in Roman Catholicism, in addition to explaining the meaning of natural law. Furthermore, the discussion focuses on metaethics and its theories, as well as a consideration of the principles of double effect (PDE) and its four conditions. Lastly, the discussion considers applications of theologically based medical ethics to the question of forgoing treatment and what are the pillars of ethics with regard to this issue. 
作为一名穆斯林,我有一个涵盖所有生活的信仰体系,包括我对医学伦理的看法。我的信仰体系与众不同,其他人也一样。因此,犹太教和罗马天主教的方法为医学伦理学提供了一个新的视角。本文的论点是,宗教因素在医疗决策中发挥着重要而不可或缺的作用。讨论的主题包括共同的价值观;方法论,以及相关的元伦理学概念和双重效应原则;以及这些观点在医学伦理学中的应用,特别是在涉及生命终结的医疗保健决策方面。本文将探讨每个领域,以便深入了解这些宗教方法是如何成为今天的样子的,以及它们如何在医学伦理学中呈现出可能与其他不基于任何神学教义的观点不一致的立场。具体来说,本文讨论了共同的价值观,通过参考人的尊严和它的概念,以及神学原则在卫生保健伦理,以及这些原则的定义。此外,本文还讨论了罗马天主教的方法论,并解释了自然法的含义。此外,本文还着重讨论了元伦理学及其理论,并对双重效应原理及其四个条件进行了思考。最后,讨论考虑了基于神学的医学伦理学在放弃治疗问题上的应用,以及关于这个问题的伦理学支柱是什么。
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引用次数: 0
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EPH - International Journal of Medical and Health Science
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