Folia medica最新文献

Introduction: The corrosion of dental alloys can have undesirable consequences. The corrosion properties may be modified by the alloy production method, composition, method of prosthetic restoration manufacturing, and oral conditions.

Introduction: Ewing sarcoma is a rare and highly aggressive primary malignant bone tumor. Early diagnosis is difficult, especially in the early stages of the disease, which often results in delays in diagnosis.

Aim: The study objective was to assess the frequency of gene alleles responsible for the metabolism and elimination of drugs in treatment-resistant patients to antipsychotics and/or antidepressants.

Introduction: Human epididymis protein 4 (HE4) is increasingly utilized in diagnosing pelvic masses and monitoring patients with ovarian or endometrial carcinoma. However, various publications and diagnostic kit manufacturers report a wide range of reference and threshold values, complicating accurate clinical interpretation and reducing the marker's clinical utility. This study aimed to establish reference values for HE4 in the Bulgarian female population and investigate the impact of physiological factors such as age, menopause, and pregnancy, as well as pathological conditions like impaired renal function, on marker levels.

Extremities are a very common site for the development of malignant tumors. A multidisciplinary approach is essential for the proper management of extremity tumors, ensuring complete surgical resection with clear margins, proper management of tissue loss, and optimal functional recovery following reconstruction. Up to 95% of patients undergo successful limb-sparing treatments, avoiding amputation. We will discuss the advantages and disadvantages of using various flaps to reconstruct upper and lower extremities. We will also explore the applications of microvascular surgery and free flaps in this context and conclude with a reflection on the timing of reconstructions.

Introduction: Over the years, pediatric tracheotomy has evolved significantly, and ongoing debates regarding its indications, timing, surgical techniques, and decannulation protocols persist. In most cases, management decisions are based on the medical team's clinical experience and existing literature, as there are no universally accepted guidelines.

We present the case of a 12-year-old boy with congenital bronchial atresia exacerbated by recurrent pulmonary infections. Born prematurely at seven months, the patient experienced recurring respiratory symptoms and persistent chest pain. Despite a month of broad-spectrum antibiotics, his symptoms persisted, and imaging tests, including computed tomography, revealed bronchial atresia. Reviewing the patient's imaging results and clinical course underscores the importance of considering congenital abnormalities when treating patients with chronic pulmonary symptoms that do not respond to traditional treatment. Early recognition of congenital bronchial atresia is vital for implementing timely therapeutic interventions. This proactive approach can help patients avoid complications, improve respiratory function, and achieve better long-term health outcomes.

Introduction: Marginal integrity can be defined as the ability of a sealant to establish a robust and resilient bond at the interface between the sealant and the tooth surface, preventing microleakage, discoloration, the formation of voids and cracks, and the subsequent development of caries lesions.

Aim: Given the documented rise in the incidence and prevalence of gout over the past decade, this study aims to comparatively assess patients of different ages affected by gout in Romania and the Republic of Moldova.

Fungal embolism of the infrarenal aorta is a rare but critical complication of infective endocarditis, associated with significant morbidity and mortality. Outcomes depend heavily on timely detection and management. Here, we present an extremely rare case of acute aortic occlusion caused by Candidaalbicans originating from a valve other than the one that was replaced. This report emphasizes the importance of recognizing atypical manifestations of endocarditis in clinical practice and the need for early antifungal therapy in high-risk patients.