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Guest editorial: the relationship between nutrition and COVID-19 客座评论:营养与COVID-19之间的关系
Pub Date : 2023-05-25 DOI: 10.1108/nfs-06-2023-479
M. Lombardo
[...]the journal Nutrition and Food Science has published this special issue exploring the intersection of nutrition and COVID-19 [1], [2], [3], [4], [5], [6], [7], [8]. [...]a study explored the factors related to sedentary lifestyle in a Brazilian sample during the COVID-19 initial quarantine [8]. [...]the papers published in the special issue "The relationship between nutrition and COVID-19” underlined the importance of nutrition in mitigating the mental and health-related impacts of the COVID-19 pandemic.
[…《营养与食品科学》杂志发表了本期特刊,探讨营养与COVID-19的交叉关系[1]、[2]、[3]、[4]、[5]、[6]、[7]、[8]。[…]一项研究探讨了在COVID-19初始隔离期间巴西样本中久坐生活方式的相关因素[8]。[…发表在《营养与COVID-19之间的关系》特刊上的论文强调了营养在减轻COVID-19大流行对精神和健康的影响方面的重要性。
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引用次数: 0
The effects of sesame oil consumption on fatigue and mental health status in women with nonalcoholic fatty liver disease: a randomized, double-blinded, controlled trial 香油消费对非酒精性脂肪肝女性患者疲劳和心理健康状况的影响:一项随机、双盲、对照试验
Pub Date : 2023-05-16 DOI: 10.1108/nfs-12-2022-0407
Masoumeh Atefi, M. Entezari, H. Vahedi
PurposeThis paper aims to examine the effect of sesame oil (SO) on fatigue and mental health status in women with nonalcoholic fatty liver disease (NAFLD) undergoing a weight-loss diet.Design/methodology/approachIn total, 60 women with NAFLD were randomly assigned to receive 30 g/day of either SO (n = 30) or sunflower oil (n = 30). All the patients received a hypocaloric diet (−500 kcal/day) for 12 weeks in a double-blinded controlled trial. Anthropometric indices, dietary intake, physical activity, fatigue and mental health status were measured at the baseline and the trial cessation.FindingsIn total, 53 participants completed the intervention. Significant reductions in anthropometric indices were observed in both groups (p-value = 0.001). Following SO, fatigue (p-value = 0.002), anxiety (p-value = 0.011) and depression (p-value = 0.013) scores were significantly reduced, while no significant changes were observed in stress scores.Originality/valueIn summary, the present study was conducted to assess the efficacy of SO consumption on fatigue and mental health status among patients with NAFLD. The results revealed SO consumption significantly reduced fatigue, anxiety and depression scores in comparison with the control group, but not for stress scores. Further clinical trials, different doses, with a longer duration of intervention, in different groups, are necessary to confirm the veracity of the results.
目的探讨香油(SO)对非酒精性脂肪性肝病(NAFLD)女性减肥饮食后疲劳和心理健康状况的影响。设计/方法/方法共60名NAFLD妇女被随机分配接受30 g/天的SO (n = 30)或葵花籽油(n = 30)。在一项双盲对照试验中,所有患者接受为期12周的低热量饮食(- 500千卡/天)。在基线和试验结束时测量人体测量指数、饮食摄入量、体力活动、疲劳和心理健康状况。总共有53名参与者完成了干预。两组的人体测量指数均显著降低(p值= 0.001)。SO后,疲劳(p值= 0.002)、焦虑(p值= 0.011)和抑郁(p值= 0.013)得分显著降低,而应激得分无显著变化。原创性/价值总之,本研究旨在评估SO消耗对NAFLD患者疲劳和心理健康状况的影响。结果显示,与对照组相比,食用SO显著降低了疲劳、焦虑和抑郁得分,但没有降低压力得分。进一步的临床试验,不同剂量,更长的干预时间,在不同的群体,是必要的,以确认结果的准确性。
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引用次数: 1
Association between neutrophil to lymphocyte ratio, handgrip strength and nutritional status in geriatric patients 老年患者中性粒细胞与淋巴细胞比值、握力和营养状况的关系
Pub Date : 2023-05-10 DOI: 10.1108/nfs-10-2022-0343
Elif Epçaçan, İdil Gönül, H. Bayram, Murat Gürbüz
PurposeThis study aims to examine the relationship between neutrophil to lymphocyte ratio (NLR), handgrip strength (HGS) and nutritional status in non-critically ill patients and outpatients.Design/methodology/approachA cross-sectional study was conducted on 80 geriatric patients. Nutritional status was evaluated using the Mini Nutritional Assessment Short Form, Geriatric Nutritional Risk Index, some anthropometric and biochemical parameters. NLR was calculated from the complete blood count results. Data were analyzed using SPSS 24.0.FindingsWhile 38.3% of patients were malnourished or at risk of malnutrition, 61.7% had normal nutritional status. Mini Nutritional Assessment Short Form was not correlated with NLR, whereas it showed a weak positive correlation with HGS. According to the logistic regression analysis, age, HGS, hemoglobin and platelet to lymphocyte ratio were significant independent factors for predicting malnutrition or risk of malnutrition. The receiver operator characteristic curve analysis showed that the optimum HGS cut-off point for patients with malnourished or at risk of malnutrition was 13.2. In conclusion, HGS was associated with the nutritional status. NLR was not associated with nutritional status but associated with nutritional risk.Originality/valueIt is well known that malnutrition is a serious health problem among older adults, and it is important to assess the nutritional status of older adults because of the adverse health effects. In addition, to the best of the authors’ knowledge, this is the first study to determine the relationship between NLR, HGS and nutritional status in non-critically ill patients and outpatients.
目的探讨非危重病人和门诊病人中性粒细胞/淋巴细胞比值(NLR)、握力(HGS)和营养状况的关系。设计/方法/方法对80例老年患者进行了横断面研究。采用迷你营养评估简表、老年营养风险指数、一些人体测量和生化参数评价营养状况。NLR根据全血细胞计数结果计算。数据采用SPSS 24.0进行分析。结果38.3%的患者存在营养不良或存在营养不良风险,61.7%的患者营养状况正常。迷你营养评估简表与NLR不相关,而与HGS呈弱正相关。经logistic回归分析,年龄、HGS、血红蛋白和血小板/淋巴细胞比值是预测营养不良或营养不良风险的显著独立因素。接受者操作者特征曲线分析显示,营养不良或有营养不良风险患者的最佳HGS分界点为13.2。综上所述,HGS与营养状况有关。NLR与营养状况无关,但与营养风险相关。众所周知,营养不良是老年人的一个严重健康问题,由于对健康的不利影响,评估老年人的营养状况是很重要的。此外,据作者所知,这是第一个确定非危重病人和门诊病人NLR、HGS和营养状况之间关系的研究。
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引用次数: 0
Determining the relationship between diet inflammatory index, mental status and quality of life in type 2 diabetes: a cross-sectional study 确定2型糖尿病患者饮食炎症指数、精神状态和生活质量之间的关系:一项横断面研究
Pub Date : 2023-05-10 DOI: 10.1108/nfs-09-2022-0323
M. Guldali, Hakan Guveli, Ferhat Çetin, E. B. Kenger, Tugce Ozlu, Can Ergun
PurposeDiabetes is one of the health problems of increasing importance owing to the increase in its incidence and the problems it causes, and it is closely related to nutrition. This study aims to determine the relationship between the dietary inflammatory index (DII) scores of individuals with type 2 diabetes, depression, anxiety and quality of life.Design/methodology/approachIn this cross-sectional study, 158 individuals with type 2 diabetes who applied to a nutrition and diet outpatient clinic of a private hospital in Istanbul were included. Their depression status was evaluated using the Beck Depression Inventory; their anxiety status was evaluated using the Beck Anxiety Inventory; and their quality of life was evaluated using the Short Form 36 Quality of Life scale. One-way ANOVA test was used to define the difference between groups. All test results were evaluated at a significance level of 0.05.FindingsThere was no significant relationship between DII scores, depression (p = 0.814) and anxiety (p = 0.817). However, a significant decrease was observed in the scores of the quality of life criterion in the groups with high depression and anxiety scores (p < 0.05). In addition, participants with high anxiety states had higher HbA1c levels (p = 0.043).Originality/valueIndividuals in this sample with no known psychiatric diagnosis or treatment history demonstrated a significant relationship between depression and anxiety scores and quality of life.
目的糖尿病的发病率和所引起的问题日益增加,是日益受到重视的健康问题之一,而糖尿病与营养密切相关。本研究旨在确定2型糖尿病患者饮食炎症指数(DII)评分与抑郁、焦虑和生活质量之间的关系。设计/方法/方法在这项横断面研究中,纳入了伊斯坦布尔一家私立医院营养和饮食门诊就诊的158例2型糖尿病患者。采用贝克抑郁量表评估抑郁状态;采用贝克焦虑量表评估其焦虑状态;他们的生活质量用36生活质量量表进行评估。采用单因素方差分析确定组间差异。所有检验结果以0.05的显著性水平进行评价。结果DII评分与抑郁(p = 0.814)、焦虑(p = 0.817)无显著相关。而抑郁、焦虑评分高组的生活质量评分明显下降(p < 0.05)。此外,高焦虑状态的参与者HbA1c水平较高(p = 0.043)。原创性/价值本样本中没有已知精神诊断或治疗史的个体表现出抑郁和焦虑得分与生活质量之间的显著关系。
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引用次数: 0
Food delivery applications and fast-food consumption during COVID-19 pandemic: a cross-sectional study COVID-19大流行期间的食品配送应用和快餐消费:一项横断面研究
Pub Date : 2023-05-03 DOI: 10.1108/nfs-02-2023-0030
Walaa Aldhamen, Maryam Aldoulah, Zainab Alghazwi, Batool Almoathen, Yassmin Almossa, Zahraa Alsalem, Razan Algarni, Tunny S. Purayidathil, Omar I. Abuzaid, Yassmin Algindan, R. Khattab
PurposeThe purpose of this study is to investigate whether the lockdown and the increased spread of food delivery applications (FD Apps) during COVID-19 pandemic have augmented the consumption of fast foods.Design/methodology/approachA cross-sectional study was conducted on 673 adults from different regions of Saudi Arabia using an online questionnaire.FindingsData showed that 61% (N = 410) of participants used FD Apps during the pandemic. Among those users, 54.9% (225) were females and 70.5% were in the 18–44 years old group. Most FD Apps’ users were university graduates (74.4%). The increased use of FD Apps during the pandemic significantly affected the eating behavior and the nutritional pattern. It has further significantly augmented the consumption of fast foods (p-value < 0.05).Originality/valueThis study reports on the use of FD Apps during COVID-19 pandemic in Saudi Arabia and its impact on consumer eating pattern. This study shows the need for prudent use of these applications to limit ordering fast foods and consider healthier choices. It further calls for education programs, awareness campaigns, legislative measures and formal policies to rationalize the use of such applications for better nutrition, health and well-being.
本研究的目的是调查COVID-19大流行期间的封锁和食品配送应用程序(FD Apps)的增加是否增加了快餐的消费。设计/方法/方法通过在线问卷调查,对来自沙特阿拉伯不同地区的673名成年人进行了横断面研究。数据显示,61% (N = 410)的参与者在大流行期间使用FD应用程序。在这些用户中,女性占54.9%(225人),18-44岁年龄组占70.5%。大多数FD app的用户是大学毕业生(74.4%)。在疫情期间,FD应用程序的使用增加显著影响了饮食行为和营养模式。它进一步显著增加了快餐的消费(p值< 0.05)。原创性/价值本研究报告了沙特阿拉伯COVID-19大流行期间FD应用程序的使用情况及其对消费者饮食模式的影响。这项研究表明,需要谨慎使用这些应用程序来限制订购快餐,并考虑更健康的选择。它还呼吁制定教育方案、提高认识运动、立法措施和正式政策,使这类应用的使用合理化,以改善营养、健康和福祉。
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引用次数: 0
Role of nutrition in minimizing mental and health-related issues during COVID-19: a systematic literature review 营养在减少COVID-19期间精神和健康相关问题中的作用:系统文献综述
Pub Date : 2023-04-18 DOI: 10.1108/nfs-12-2022-0421
L. Sharma, Dhananjay Sharma
PurposeThis study aims to conduct a systematic literature review to investigate the mental health problems during COVID-19 and the role of nutrition in minimizing mental and health-related issues during COVID-19.Design/methodology/approachA literature search was done electronically on April–May 2022 in the databases Google Scholar, PubMed and Cochrane Library, reviewing all the articles published in English. There were no limitations for the study (such as study design, region or any time frame). The quality assessment was done. The beginning database search picked out a total of 654 articles, 47 in PubMed, 575 in Google Scholar, 22 in Cochrane Library and 10 records from other sources. A total of 565 (duplicates found 89) were found after removing the duplicated articles, after reading the title and abstracts were further decreased to 88 full-text articles. These 88 studies went for full-text analysis, which excluded 56 studies and generated a final 32 articles for systemic analysis. The quality of the included study for the systematic review was assessed in two ways: one is evidence-based and another one on the JBI checklist.FindingsPeople in social isolation and home quarantine suffer from severe anxiety, stress, depression, loneliness, anger and panic attack. During COVID-19, the vital role of diet and nutrients in mental health has been acknowledged and helps mitigate COVID-19 infection. Many studies showed stress and anxiety due to increased unhealthy eating and lifestyle practices.Originality/valueThis review will explain the interlink between diet and mental health because what we eat and think is interconnected with the gut–brain axis. The dietary elements and psychobiotic help in improving the immune system and psychological distress during the pandemic. This paper describes the role of different nutrients, psychobiotics and phytochemicals, to minimize mental and health issues during the COVID-19 pandemic. This paper also contains a balanced diet plan to withstand COVID-19.
目的通过系统的文献综述,探讨新冠肺炎期间的心理健康问题,以及营养在减少新冠肺炎期间心理健康问题中的作用。设计/方法/方法于2022年4 - 5月在b谷歌Scholar、PubMed和Cochrane Library数据库中进行电子文献检索,审查所有以英文发表的文章。本研究没有任何限制(如研究设计、地区或任何时间框架)。进行了质量评价。开始的数据库检索总共挑选了654篇文章,其中47篇来自PubMed, 575篇来自b谷歌Scholar, 22篇来自Cochrane Library,还有10条来自其他来源的记录。删除重复文章后共发现565篇(重复89篇),阅读标题和摘要后全文文章进一步减少至88篇。这88项研究进行了全文分析,排除了56项研究,并产生了最终的32篇文章进行系统分析。系统评价纳入研究的质量以两种方式评估:一种是基于证据的,另一种是基于JBI检查表的。社会隔离和家庭隔离的人患有严重的焦虑、压力、抑郁、孤独、愤怒和恐慌症。在2019冠状病毒病期间,饮食和营养素在精神健康方面的重要作用已得到承认,并有助于减轻COVID-19感染。许多研究表明,压力和焦虑是由于不健康的饮食和生活方式的增加。原创性/价值这篇综述将解释饮食和心理健康之间的相互联系,因为我们吃的和想的是与肠脑轴相互联系的。饮食元素和心理生物制剂有助于在大流行期间改善免疫系统和心理困扰。本文介绍了不同营养物质、精神生物制剂和植物化学物质在COVID-19大流行期间减少精神和健康问题方面的作用。本文还包含了抵御COVID-19的均衡饮食计划。
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引用次数: 0
Adherence to the Mediterranean diet in Greek adolescents during COVID-19: exploring determining factors through cross-sectional study COVID-19期间希腊青少年坚持地中海饮食:通过横断面研究探索决定因素
Pub Date : 2023-04-18 DOI: 10.1108/nfs-12-2022-0419
S. Papadaki, V. Carayanni, V. Notara, D. Chaniotis
PurposeDuring the pandemic, people have changed their diet and lifestyle, which are highly important to maintain health and well-being. This study aims to investigate the relationship between demographic, socioeconomic, dietary and lifestyle characteristics and adolescents' adherence to the Mediterranean diet (AMD).Design/methodology/approachIn all, 2088 youth from Attica, Greece, 12–18 years old, were recruited in this school-based, cross-sectional study conducted in May–December 2021. The tools Mediterranean Diet Quality Index for children and adolescents, the Family Affluence Scale III and the Godin-Shephard Leisure Time Physical Activity Questionnaire were used to estimate AMD, family affluence and the levels of physical activity (PA), respectively. Mann–Whitney U, Kruskal–Wallis, Chi-square tests, analysis of variance and multiple linear regression approaches were applied.FindingsEmpirical results showed that boys (p = 0.000), higher socioeconomic status (p = 0.034) and higher maternal education (p = 0.026) emerged as significant determinants for higher AMD. In addition, healthier dietary patterns (p = 0.000), PA (p = 0.000), more social lifestyle (p = 0.000) and night sleep duration (p = 0.000) were also positively correlated to diet quality. On the contrary, age (p = 0.000), screen time (p = 0.003) and the negative consequences of COVID-19 affected adversely AMD among adolescents.Originality/valueTo the best of the authors’ knowledge, this study was the first that highlighted the important role of several demographic, socioeconomic, dietary and lifestyle characteristics, together with the COVID-19 consequences to the AMD among secondary school children in Greece.
目的大流行期间,人们改变了饮食和生活方式,这对保持健康和福祉非常重要。本研究旨在探讨人口统计学、社会经济、饮食和生活方式特征与青少年坚持地中海饮食(AMD)之间的关系。设计/方法/方法在2021年5月至12月进行的这项以学校为基础的横断面研究中,共招募了2088名来自希腊阿提卡的12-18岁青年。采用儿童和青少年地中海饮食质量指数、家庭富裕量表III和Godin-Shephard休闲时间体力活动问卷分别评估AMD、家庭富裕和体力活动水平。采用Mann-Whitney U、Kruskal-Wallis、卡方检验、方差分析和多元线性回归方法。研究结果显示,男孩(p = 0.000)、较高的社会经济地位(p = 0.034)和较高的母亲教育程度(p = 0.026)是发生AMD的显著决定因素。此外,更健康的饮食模式(p = 0.000)、PA (p = 0.000)、更多的社交生活方式(p = 0.000)和夜间睡眠时间(p = 0.000)也与饮食质量呈正相关。相反,年龄(p = 0.000)、屏幕时间(p = 0.003)和COVID-19的负面后果对青少年的AMD有不利影响。原创性/价值据作者所知,这项研究首次强调了几种人口、社会经济、饮食和生活方式特征的重要作用,以及COVID-19对希腊中学生AMD的影响。
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引用次数: 0
Is “stay-at-home” synonymous of inactivity? Factors related to sedentary lifestyle in a Brazilian sample during COVID-19 initial quarantine “呆在家里”是不活动的同义词吗?在COVID-19初始隔离期间,巴西样本中与久坐生活方式相关的因素
Pub Date : 2023-04-07 DOI: 10.1108/nfs-11-2022-0390
Tamires Cássia de Melo Souza, L. Oliveira, J. Liboredo, C. M. Della Lucia, L. Ferreira, M. M. Daniel, L. Anastácio
PurposeThe purpose of this study is to describe the prevalence of a sedentary lifestyle (<150 min of physical exercise/week) and associated factors of this behavior in Brazil.Design/methodology/approachAn observational study was conducted through an online questionnaire in August–September 2020 (5.5 months after the beginning of the pandemic in the country). Socioeconomic, lifestyle, anthropometric, dietary and perceived stress data were evaluated as possible related factors to a sedentary lifestyle through multiple logistic regression analysis.FindingsA total of 1,347 individuals were evaluated (median of 31 years old, 80.1% women), of whom 76.7% were considered sedentary. Associated factors to a sedentary lifestyle were being overweight; a greater difference between current weight and prepandemic weight; female sex; lower percentage of home-cooked meals; greater increase in the frequency of consumption of alcoholic beverages; higher frequency of consumption of cereals, sausages and sweets during the pandemic; and higher score of perceived stress.Originality/valueTo the best of the authors’ knowledge, no studies have aimed to reveal the associated factors to a sedentary lifestyle during the COVID-19 pandemic in Brazil. Protective factors against a sedentary lifestyle were eating breakfast, being a student, living with parents, a higher frequency of fruit consumption, a higher rate of alcohol consumption and a higher cognitive restriction of food intake during the pandemic. Most of the study participants were sedentary, especially women. A sedentary lifestyle was associated with worse lifestyle/eating habits and stress. Such findings encourage an interdisciplinary approach because habits and lifestyle have numerous interferences.
目的本研究的目的是描述巴西久坐不动的生活方式(<150分钟的体育锻炼/周)的流行程度及其相关因素。设计/方法/方法于2020年8月至9月(该国大流行开始5.5个月后)通过在线问卷进行了一项观察性研究。通过多元logistic回归分析,评估社会经济、生活方式、人体测量、饮食和感知压力数据作为久坐生活方式的可能相关因素。共有1347人接受了评估(中位数为31岁,80.1%为女性),其中76.7%的人被认为是久坐不动的。与久坐不动的生活方式相关的因素是超重;当前体重与大流行前体重之间的差异更大;女性性;家常菜的比例较低;饮用含酒精饮料的频率大幅增加;大流行期间食用谷物、香肠和糖果的频率更高;感知压力的得分也更高。据作者所知,没有研究旨在揭示巴西COVID-19大流行期间久坐不动的生活方式的相关因素。防止久坐不动的生活方式的保护因素是吃早餐、作为学生、与父母住在一起、更频繁地食用水果、更高的饮酒率以及在大流行期间对食物摄入的认知限制更高。大多数研究参与者都是久坐不动的,尤其是女性。久坐不动的生活方式与不良的生活方式/饮食习惯和压力有关。这些发现鼓励跨学科的研究方法,因为习惯和生活方式有许多干扰。
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引用次数: 1
The positive relationship between NUTRIC score, bioelectric measures and hospital mortality in critically ill patients 危重病人NUTRIC评分、生物电测量与住院死亡率呈正相关
Pub Date : 2023-03-28 DOI: 10.1108/nfs-09-2022-0321
R.L.U. Ferreira, Miriam Farias da Silva, Nathalya Julianny de Macedo Olimpio, M. Oliveira, K. M. Vermeulen-Serpa, J. Brandão-Neto, Sancha Helena Lima Vale, L. Leite-Lais, M. Lopes
PurposeBioelectrical impedance vector analysis (BIVA) and phase angle (PA) have importance in assessing nutritional and prognosis, and this study hypothesized that these measurements can have a relationship with nutritional risk and outcomes. This study aims to analyze the association between Nutrition Risk in the Critically ill (NUTRIC) score and bioelectrical impedance measures with hospital mortality in critically ill patients.Design/methodology/approachA prospective, cohort study was performed with a consecutive sample of patients admitted to an intensive care unit (ICU), between January and June 2017 at a hospital university in Northwest Brazil. The NUTRIC score and the bioelectric measures, such as resistance (R), reactance (Xc), PA and BIVA, were completed within the first 24 h of admission. The Student’s t or Mann–Whitney, Pearson’s or Spearman’s coefficient and Fisher’s exact tests and BIVA were used for statistical analyses.FindingsThe sample consisted of 81, with a mean age of 57 (16.7) years, with 60.5% women. It was detected that PA and Xc were lower (p < 0.001), and age was higher (p < 0.001) in a high nutritional-risk group. It was found an association between low nutritional risk and hospital discharge (p < 0.001), and that individuals who died spent more days in the ICU (p = 0.0375), had significantly lower PA and Xc values (p = 0.043 and p = 0.0172, respectively) and higher NUTRIC scores (<0.0001). There was a displacement of the mean impedance vector in men and women with high nutritional risk (p = 0.0037 and p = 0.004, respectively).Research limitations/implicationsThe height measurement was estimated using predictive formulas, which may affect the accuracy of the values; BIA was performed only upon admission of the patient to the ICU and the study population was heterogeneous, as it is a general ICU.Originality/valueThis paper shows that, in critically ill patients, nutritional screening and the assessment of bioelectrical measures help in clinical-nutritional decisions, and were able to predict outcomes.
目的生物电阻抗矢量分析(BIVA)和相位角(PA)在评估营养和预后方面具有重要意义,本研究假设这些测量可能与营养风险和预后有关。本研究旨在分析危重病人营养风险(NUTRIC)评分和生物电阻抗测量与危重病人住院死亡率的关系。设计/方法/方法:2017年1月至6月,在巴西西北部一所医院大学对入住重症监护病房(ICU)的患者进行了一项前瞻性队列研究。入院前24小时内完成NUTRIC评分和电阻(R)、电抗(Xc)、PA、BIVA等生物电测量。采用Student 's t或Mann-Whitney系数、Pearson 's或Spearman 's系数、Fisher 's精确检验和BIVA进行统计分析。研究结果样本包括81人,平均年龄为57岁(16.7岁),其中60.5%为女性。高营养风险组PA、Xc较低(p < 0.001),年龄较高(p < 0.001)。研究发现,低营养风险与出院之间存在关联(p < 0.001),死亡患者在ICU呆的时间较长(p = 0.0375), PA和Xc值显著降低(p = 0.043和p = 0.0172), NUTRIC评分较高(p <0.0001)。在营养风险高的男性和女性中,平均阻抗矢量发生位移(p = 0.0037和p = 0.004)。研究局限/启示高度测量是使用预测公式估计的,可能会影响数值的准确性;BIA仅在患者进入ICU时进行,研究人群是异质性的,因为它是一个普通的ICU。原创性/价值本文表明,在危重患者中,营养筛查和生物电测量评估有助于临床营养决策,并能够预测结果。
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引用次数: 0
Iron-fortified klutuk banana (Musa balbisiana Colla) flour supplementation prevented growth failure by suppressing FGF21 in malnourished rats 补充铁强化克鲁图克香蕉(Musa balbisiana Colla)面粉通过抑制营养不良大鼠的FGF21来防止生长失败
Pub Date : 2023-03-07 DOI: 10.1108/nfs-05-2022-0165
Abdullah Syafiq Edyanto, E. Huriyati, A. Nisa, Bira Arumndari Nurrahma, A. Farmawati
PurposeMalnutrition during childhood precedes growth failure and affects the child’s well-being later in life. This study aims to investigate the potency of iron-fortified klutuk banana (Musa balbisiana Colla) flour on growth parameters and fibroblast growth factor 21 (FGF21) expression in malnourished rat model.Design/methodology/approachRats were allocated into normal control (NC), untreated malnutrition (MC), malnutrition + iron-fortified klutuk banana flour (IBF) and malnutrition + Indonesian Government-issued biscuit (GB). Malnutrition was induced by an isoenergetic low-protein diet for five weeks. The IBF and GB groups were supplemented with IBF 1.2 g/200 gBW and GB 1.2 g/200 gBW, respectively, via gavage daily for three weeks. The body weight and length, the levels of plasma and liver FGF21 and red blood cell indices were analyzed.FindingsAfter three weeks of supplementation, the IBF group showed higher body weight (245 ± 13.6 g vs 201.8 ± 16.3 g; p = 0.0004) and length (20.9 ± 0.5 cm vs 19.8 ± 0.5 cm; p = 0.021) compared with the untreated group. The plasma FGF21 level decreased in the IBF group (p = 0.034). The IBF group altered mean corpuscular volume and mean corpuscular hemoglobin, suggesting the IBF might attenuate malnutrition-induced anemia. Overall, the IBF prevented growth failure in malnourished condition. This might be mediated by the suppression of FGF21 expression, along with the prevention of malnutrition and anemia.Originality/valueThis study provides preliminary information about the potential use of rarely consumed banana, klutuk banana, as a supplement to treat malnutrition. This study might help the developing countries to eliminate the widespread malnutrition in economically challenged communities.
目的:儿童时期的营养不良先于生长衰竭,并影响儿童以后的健康。本研究旨在探讨铁强化克鲁图克香蕉(Musa balbisiana Colla)粉对营养不良大鼠模型生长参数和成纤维细胞生长因子21 (FGF21)表达的影响。设计/方法/方法将大鼠分为正常对照组(NC)、未处理营养不良组(MC)、营养不良组+铁强化klutuk香蕉粉组(IBF)和营养不良组+印尼政府发行的饼干组(GB)。等能低蛋白饮食5周诱导营养不良。IBF组和GB组分别添加IBF 1.2 g/200 gBW和GB 1.2 g/200 gBW,每天灌胃3周。分析大鼠体重、体长、血浆和肝脏FGF21水平及红细胞指标。结果:补充3周后,IBF组体重增加(245±13.6 g vs 201.8±16.3 g);p = 0.0004)和长度(20.9±0.5厘米和19.8±0.5厘米;P = 0.021)。IBF组血浆FGF21水平降低(p = 0.034)。IBF组改变了平均红细胞体积和平均红细胞血红蛋白,提示IBF可能减轻营养不良引起的贫血。总体而言,IBF可防止营养不良条件下的生长衰竭。这可能是通过抑制FGF21的表达,以及预防营养不良和贫血来介导的。原创性/价值本研究提供了关于很少食用的香蕉klutuk香蕉作为治疗营养不良补充剂的潜在用途的初步信息。这项研究可能有助于发展中国家消除经济困难社区普遍存在的营养不良。
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Food Science &amp; Nutrition
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