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Correction to “Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model”
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-25 DOI: 10.1002/fsn3.70210

Ashan, T., Maria, N.N., Jasmin, A.A., Tahmida, U., and Singha, S. (2025), Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model. Food Sci Nutr, 13: e4631. https://doi.org/10.1002/fsn3.4631

In the originally published article, the order of authors was incorrect. The correct order is: Nazratun Noor Maria, Ayesha Akter Jasmin, Umme Tahmida, Saurav Singha, and Tanveer Ahsan

The citation should read as Maria, N.N., Jasmin, A.A., Tahmida, U., Singha, S., and Ahsan, T. (2025), Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model. Food Sci Nutr, 13: e4631. https://doi.org/10.1002/fsn3.4631

The online version has been corrected accordingly.

We apologize for this error.

{"title":"Correction to “Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model”","authors":"","doi":"10.1002/fsn3.70210","DOIUrl":"https://doi.org/10.1002/fsn3.70210","url":null,"abstract":"<p>\u0000 <span>Ashan, T.</span>, <span>Maria, N.N.</span>, <span>Jasmin, A.A.</span>, <span>Tahmida, U.</span>, and <span>Singha, S.</span> (<span>2025</span>), <span>Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model</span>. <i>Food Sci Nutr</i>, <span>13</span>: e4631. https://doi.org/10.1002/fsn3.4631\u0000 </p><p>In the originally published article, the order of authors was incorrect. The correct order is: Nazratun Noor Maria, Ayesha Akter Jasmin, Umme Tahmida, Saurav Singha, and Tanveer Ahsan</p><p>The citation should read as Maria, N.N., Jasmin, A.A., Tahmida, U., Singha, S., and Ahsan, T. (2025), Investigation on Anti-Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model. Food Sci Nutr, 13: e4631. https://doi.org/10.1002/fsn3.4631</p><p>The online version has been corrected accordingly.</p><p>We apologize for this error.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70210","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Properties and Application Potential of β-Glucan in Skin Care
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-25 DOI: 10.1002/fsn3.70212
Xiaoyue Feng, Jianli Shang, Yuhui Wang, Yong Chen, Youting Liu

β-glucan is a natural polysaccharide widely found in plants, fungi, bacteria, and algae. Due to its significant immunomodulatory effects, it has become an important source for functional foods and pharmaceuticals. In addition to immune regulation, β-glucan also exhibits various bioactivities, including antioxidant, anti-inflammatory, barrier repair, and moisturizing effects, demonstrating great potential for applications in skin care. Its biological activity is influenced by factors such as its source, molecular structure, and physicochemical properties. This review systematically explores the relationship between the properties and functions of β- glucan, investigates its biological mechanisms, and summarizes its clinical applications and future prospects in skin care. The aim of this paper is to provide theoretical support for the development of β-glucan in the field of skin health and offer references for future related research and clinical practice.

{"title":"Exploring the Properties and Application Potential of β-Glucan in Skin Care","authors":"Xiaoyue Feng,&nbsp;Jianli Shang,&nbsp;Yuhui Wang,&nbsp;Yong Chen,&nbsp;Youting Liu","doi":"10.1002/fsn3.70212","DOIUrl":"https://doi.org/10.1002/fsn3.70212","url":null,"abstract":"<p>β-glucan is a natural polysaccharide widely found in plants, fungi, bacteria, and algae. Due to its significant immunomodulatory effects, it has become an important source for functional foods and pharmaceuticals. In addition to immune regulation, β-glucan also exhibits various bioactivities, including antioxidant, anti-inflammatory, barrier repair, and moisturizing effects, demonstrating great potential for applications in skin care. Its biological activity is influenced by factors such as its source, molecular structure, and physicochemical properties. This review systematically explores the relationship between the properties and functions of β- glucan, investigates its biological mechanisms, and summarizes its clinical applications and future prospects in skin care. The aim of this paper is to provide theoretical support for the development of β-glucan in the field of skin health and offer references for future related research and clinical practice.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to “Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake”
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-25 DOI: 10.1002/fsn3.70207

Peng L, Zhang Q, Zhang Y, et al. Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake. Food Sci Nutr. 2020; 8: 199–213. https://doi.org/10.1002/fsn3.1291

The Correspondence section contained errors. The correct information is as follows:

Correspondence

Zhu-Yun Yan, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Email: [email protected]

Gang Zhao, Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu 610106, China.

Email: [email protected]

In Figure 4, the image for Group HFDB was mistakenly duplicated in Group HFDR. This mistake occurred during the process of assembling the figure and does not affect the results, analysis, or conclusions presented in the manuscript.

The corrected Figure 4 appears below.

We apologize for this error.

{"title":"Correction to “Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake”","authors":"","doi":"10.1002/fsn3.70207","DOIUrl":"https://doi.org/10.1002/fsn3.70207","url":null,"abstract":"<p>Peng L, Zhang Q, Zhang Y, et al. Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake. <i>Food Sci Nutr</i>. 2020; 8: 199–213. https://doi.org/10.1002/fsn3.1291</p><p>The Correspondence section contained errors. The correct information is as follows:</p><p>\u0000 <b>Correspondence</b>\u0000 </p><p>Zhu-Yun Yan, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.</p><p>Email: <span>[email protected]</span></p><p>Gang Zhao, Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu 610106, China.</p><p>Email: <span>[email protected]</span></p><p>In Figure 4, the image for Group HFDB was mistakenly duplicated in Group HFDR. This mistake occurred during the process of assembling the figure and does not affect the results, analysis, or conclusions presented in the manuscript.</p><p>The corrected Figure 4 appears below.</p><p>We apologize for this error.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Probiotic Properties of Lacticaseibacillus casei 4 N-6 Strain Isolated From Cow Milk
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-24 DOI: 10.1002/fsn3.70205
Neslihan Dikbaş, Yusuf Can Orman, Sevda Uçar, Şeyma Alım

The aim of the present study was to characterize the probiotic potential of Lacticaseibacillus casei 4 N-6 strain isolated from cow's milk. For this purpose, acid, bile salt, pancreatin, pepsin, phenol, and lysozyme tolerance, co-aggregation and auto-aggregation properties, phytase production, antibiotic resistance, and antibacterial properties were analyzed in vitro. The strain had relatively poor acid, bile salt, and pepsin tolerance. However, the strain showed a high pancreatin, lysozyme, and phenol tolerance. In addition, it exhibited moderate co-aggregation with E. coli and good autoaggregation. Furthermore, the cell-free supernatant of Lb. casei 4 N-6 showed a high antimicrobial activity against Bacillus cereus (N32), Salmonella enteritidis (RK-485), and Enterococcus faecalis (RK-487). 4 N-6 was resistant to vancomycin, teicoplanin, gentamicin, and ceflazidime. The 4 N-6 strain did not show hemolytic activity. In addition, this strain was found to be able to produce phytase. All the findings obtained indicate that Lb. casei 4 N-6 is promising as a potential probiotic candidate and has superior properties that can be evaluated as a probiotic in the future. However, further research and in vivo studies are needed to fully understand its mechanism of action and optimize its use as a probiotic.

{"title":"Investigation of Probiotic Properties of Lacticaseibacillus casei 4 N-6 Strain Isolated From Cow Milk","authors":"Neslihan Dikbaş,&nbsp;Yusuf Can Orman,&nbsp;Sevda Uçar,&nbsp;Şeyma Alım","doi":"10.1002/fsn3.70205","DOIUrl":"https://doi.org/10.1002/fsn3.70205","url":null,"abstract":"<p>The aim of the present study was to characterize the probiotic potential of <i>Lacticaseibacillus casei</i> 4 N-6 strain isolated from cow's milk. For this purpose, acid, bile salt, pancreatin, pepsin, phenol, and lysozyme tolerance, co-aggregation and auto-aggregation properties, phytase production, antibiotic resistance, and antibacterial properties were analyzed in vitro. The strain had relatively poor acid, bile salt, and pepsin tolerance. However, the strain showed a high pancreatin, lysozyme, and phenol tolerance. In addition, it exhibited moderate co-aggregation with <i>E. coli</i> and good autoaggregation. Furthermore, the cell-free supernatant of <i>Lb</i>. <i>casei</i> 4 N-6 showed a high antimicrobial activity against <i>Bacillus cereus</i> (N32), <i>Salmonella enteritidis</i> (RK-485), and <i>Enterococcus faecalis</i> (RK-487). 4 N-6 was resistant to vancomycin, teicoplanin, gentamicin, and ceflazidime. The 4 N-6 strain did not show hemolytic activity. In addition, this strain was found to be able to produce phytase. All the findings obtained indicate that <i>Lb</i>. <i>casei</i> 4 N-6 is promising as a potential probiotic candidate and has superior properties that can be evaluated as a probiotic in the future. However, further research and in vivo studies are needed to fully understand its mechanism of action and optimize its use as a probiotic.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic Changes of Microbial Communities and Chemical Compounds During the Dry Processing of Coffea arabica
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-24 DOI: 10.1002/fsn3.70178
Xiaojing Shen, Qi Wang, Biao Yuan, Zhiheng Yin, Muzi Li, Runxin Shi, Kunyi Liu, Wenjuan Yuan

Coffee is a globally popular beverage and a significant agricultural economic crop in planted countries and regions. To understand the influence of primary processing on coffee, the microbial communities and chemical compounds were analyzed using high-throughput sequencing and HPLC-MS/MS metabolomics to confirm the dynamic changes of them during the dry processing of Coffea arabica from Yunnan, China. The results showed that Tatumella, Klebsiella, Gluconobacter, Brevundimonas, and Staphylococcus at the bacterial general level and Candida, Lachancea, Aschersonia, Cercospora, and Pichia at the fungi general level were the predominant microorganisms in the dry processing. During the dry process, Tatumella, Gluconobacter, and Candida showed a trend of increasing firstly and decreasing subsequently, while Klebsiella and Lachancea reached the highest at the end of processing. In contrast, Hannaella decreased gradually. Meanwhile, 1551 chemical compounds coming from 15 superclasses were detected. Furthermore, 129 differentially changed compounds (DCCs) including 91 upregulated DCCs with VIP > 1.0, p < 0.05, and FC > 1.5 and 38 downregulated DCCs with VIP > 1.0, p < 0.05, and FC < 0.67 were determined in finished samples versus raw materials. Among them, cis-5-caffeoylquinic acid and sesamose were very significantly DCCs. Therefore, this study can provide useful information for understanding the dry processing of coffee beans and its impact on coffee's quality properties.

{"title":"Dynamic Changes of Microbial Communities and Chemical Compounds During the Dry Processing of Coffea arabica","authors":"Xiaojing Shen,&nbsp;Qi Wang,&nbsp;Biao Yuan,&nbsp;Zhiheng Yin,&nbsp;Muzi Li,&nbsp;Runxin Shi,&nbsp;Kunyi Liu,&nbsp;Wenjuan Yuan","doi":"10.1002/fsn3.70178","DOIUrl":"https://doi.org/10.1002/fsn3.70178","url":null,"abstract":"<p>Coffee is a globally popular beverage and a significant agricultural economic crop in planted countries and regions. To understand the influence of primary processing on coffee, the microbial communities and chemical compounds were analyzed using high-throughput sequencing and HPLC-MS/MS metabolomics to confirm the dynamic changes of them during the dry processing of <i>Coffea arabica</i> from Yunnan, China. The results showed that <i>Tatumella</i>, <i>Klebsiella</i>, <i>Gluconobacter</i>, <i>Brevundimonas</i>, and <i>Staphylococcus</i> at the bacterial general level and <i>Candida</i>, <i>Lachancea</i>, <i>Aschersonia</i>, <i>Cercospora</i>, and <i>Pichia</i> at the fungi general level were the predominant microorganisms in the dry processing. During the dry process, <i>Tatumella</i>, <i>Gluconobacter</i>, and <i>Candida</i> showed a trend of increasing firstly and decreasing subsequently, while <i>Klebsiella</i> and <i>Lachancea</i> reached the highest at the end of processing. In contrast, <i>Hannaella</i> decreased gradually. Meanwhile, 1551 chemical compounds coming from 15 superclasses were detected. Furthermore, 129 differentially changed compounds (DCCs) including 91 upregulated DCCs with VIP &gt; 1.0, <i>p</i> &lt; 0.05, and FC &gt; 1.5 and 38 downregulated DCCs with VIP &gt; 1.0, <i>p</i> &lt; 0.05, and FC &lt; 0.67 were determined in finished samples versus raw materials. Among them, cis-5-caffeoylquinic acid and sesamose were very significantly DCCs. Therefore, this study can provide useful information for understanding the dry processing of coffee beans and its impact on coffee's quality properties.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biodetoxification of Aflatoxin M1 in Artificially Contaminated Fermented Milk, Fermented Dairy Drink and Yogurt Using Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus reuteri, and Lactobacillus rhamnosus and Its Effects on Physicochemical Properties
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-24 DOI: 10.1002/fsn3.70175
Fatemeh Moradkhani, Seyed Saeed Sekhavatizadeh, Mohammad Hosein Marhamatizadeh, Maryam Ghasemi

The aim of this research was to examine the occurrence of aflatoxin M1 (AFM1) in milk collected from Shiraz, Iran. Moreover, the capacity of the four probiotic species to reduce the concentration of AFM1 was assessed. For this research, 10 raw milk samples were collected randomly in Shiraz, Iran, in January 2023. The analyses were performed using an HPLC system equipped with a fluorescence detector. Then, AFM1 artificially contaminated probiotic drink milk (PDM) containing Lactobacillus plantarum (LP), Lactobacillus reuteri (LRE), Lactobacillus rhamnosus (LR) (LABs) alone or in combination, fermented dairy drink containing Lactobacillus acidophilus (FDD-LA), and yogurt were produced. The pH, total viable number of probiotics (TVNP), and rheology of the samples were measured. In all milk samples, the concentrations of AFM1 did not exceed the maximum threshold established by Iranian national standards. In the artificially spiked samples, the maximal reduction in AFM1 was noted in PDMLP (96.5%), PDMLP-LRE-LR (95.3%), yogurt (95.2%), and PDMLR (93.8%). FDD-LA revealed the lowest reduction in AFM1 (75.9%). The TVNP increased during processing, while the pH decreased in all the samples. AFM1 did not have any negative effect on TVNP or pH. The SEM images revealed that the AFM1-treated samples had a less compact structure and more cavities. Similarly, the viscosity of the control sample without AFM1 was greater than that of the AFM1-supplemented samples. The results showed that LP, LRE, LR, LA, and yogurt starter cultures have a strong ability to decrease AFM1 in milk. However, their effect on the textural properties of the product is not favorable.

{"title":"Biodetoxification of Aflatoxin M1 in Artificially Contaminated Fermented Milk, Fermented Dairy Drink and Yogurt Using Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus reuteri, and Lactobacillus rhamnosus and Its Effects on Physicochemical Properties","authors":"Fatemeh Moradkhani,&nbsp;Seyed Saeed Sekhavatizadeh,&nbsp;Mohammad Hosein Marhamatizadeh,&nbsp;Maryam Ghasemi","doi":"10.1002/fsn3.70175","DOIUrl":"https://doi.org/10.1002/fsn3.70175","url":null,"abstract":"<p>The aim of this research was to examine the occurrence of aflatoxin M1 (AFM1) in milk collected from Shiraz, Iran. Moreover, the capacity of the four probiotic species to reduce the concentration of AFM1 was assessed. For this research, 10 raw milk samples were collected randomly in Shiraz, Iran, in January 2023. The analyses were performed using an HPLC system equipped with a fluorescence detector. Then, AFM1 artificially contaminated probiotic drink milk (PDM) containing <i>Lactobacillus plantarum</i> (LP), <i>Lactobacillus reuteri</i> (LRE), <i>Lactobacillus rhamnosus</i> (LR) (LABs) alone or in combination, fermented dairy drink containing <i>Lactobacillus acidophilus</i> (FDD-LA), and yogurt were produced. The pH, total viable number of probiotics (TVNP), and rheology of the samples were measured. In all milk samples, the concentrations of AFM1 did not exceed the maximum threshold established by Iranian national standards. In the artificially spiked samples, the maximal reduction in AFM1 was noted in PDM<sub>LP</sub> (96.5%), PDM<sub>LP-LRE-LR</sub> (95.3%), yogurt (95.2%), and PDM<sub>LR</sub> (93.8%). FDD-LA revealed the lowest reduction in AFM1 (75.9%). The TVNP increased during processing, while the pH decreased in all the samples. AFM1 did not have any negative effect on TVNP or pH. The SEM images revealed that the AFM1-treated samples had a less compact structure and more cavities. Similarly, the viscosity of the control sample without AFM1 was greater than that of the AFM1-supplemented samples. The results showed that LP, LRE, LR, LA, and yogurt starter cultures have a strong ability to decrease AFM1 in milk. However, their effect on the textural properties of the product is not favorable.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L-Theanine Ameliorates Doxorubicin-Induced Ovarian Toxicity by Reducing Endoplasmic Reticulum Stress
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-24 DOI: 10.1002/fsn3.70150
Meltem Arıkan Malkoç, Serap Özer Yaman, Esin Yuluğ, Semanur Işık, Birgül Kural

Doxorubicin (DOX) is an anthracycline antibiotic widely used as an antineoplastic agent. L-theanine (LTN) is a unique amino acid obtained from tea (Camellia sinensis) and a highly valuable nutraceutical additive in the food industry. The aim of this study was to investigate the effects of LTN on ovarian endoplasmic reticulum stress (ERS) in DOX-induced rats. The rats were divided into one of four groups: Control (saline), DOX (20 mg/kg DOX, i.p.), DOX + LTN200 (DOX + 200 mg/kg LTN) and DOX + LTN400 (DOX + 400 mg/kg LTN). DOX was administered on the first day, followed by three consecutive days of LTN via oral gavage. The levels of ERS (GRP78, IRE1, and CHOP), oxidative stress (TOS, OSI, and MDA), inflammation (TNF-α) and fertility (E2 and PGN) parameters were analyzed using ELISA or assay kits. In addition, morphological and apoptotic (DNA fragmentation) changes in ovarian tissues were examined histologically. The study found that both doses of LTN were effective in reversing DOX-induced ERS by lowering oxidative stress, inflammation, and apoptosis, and alleviating morphological changes. However, the 400 mg/kg LTN group exhibited more significant effects. LTN treatment thus has the potential to alleviate the adverse effects on ovarian tissue caused by DOX by modulating the endoplasmic reticulum (ER) stress response and associated conditions.

{"title":"L-Theanine Ameliorates Doxorubicin-Induced Ovarian Toxicity by Reducing Endoplasmic Reticulum Stress","authors":"Meltem Arıkan Malkoç,&nbsp;Serap Özer Yaman,&nbsp;Esin Yuluğ,&nbsp;Semanur Işık,&nbsp;Birgül Kural","doi":"10.1002/fsn3.70150","DOIUrl":"https://doi.org/10.1002/fsn3.70150","url":null,"abstract":"<p>Doxorubicin (DOX) is an anthracycline antibiotic widely used as an antineoplastic agent. L-theanine (LTN) is a unique amino acid obtained from tea (<i>Camellia sinensis</i>) and a highly valuable nutraceutical additive in the food industry. The aim of this study was to investigate the effects of LTN on ovarian endoplasmic reticulum stress (ERS) in DOX-induced rats. The rats were divided into one of four groups: Control (saline), DOX (20 mg/kg DOX, i.p.), DOX + LTN200 (DOX + 200 mg/kg LTN) and DOX + LTN400 (DOX + 400 mg/kg LTN). DOX was administered on the first day, followed by three consecutive days of LTN via oral gavage. The levels of ERS (GRP78, IRE1, and CHOP), oxidative stress (TOS, OSI, and MDA), inflammation (TNF-α) and fertility (E2 and PGN) parameters were analyzed using ELISA or assay kits. In addition, morphological and apoptotic (DNA fragmentation) changes in ovarian tissues were examined histologically. The study found that both doses of LTN were effective in reversing DOX-induced ERS by lowering oxidative stress, inflammation, and apoptosis, and alleviating morphological changes. However, the 400 mg/kg LTN group exhibited more significant effects. LTN treatment thus has the potential to alleviate the adverse effects on ovarian tissue caused by DOX by modulating the endoplasmic reticulum (ER) stress response and associated conditions.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective Effect of Cast-Off Skin of Cicadidae Periostracum Water Extract in a Radiation-Induced Testicular Injury Mice Model
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-24 DOI: 10.1002/fsn3.70198
Yun-Soo Seo, Seung Mok Ryu, Jun Lee, Huiyeong Jeong, Goya Choi, Byeong Cheol Moon, Je-Oh Lim, Hyeon-Hwa Nam, Joong-Sun Kim, Sueun Lee

Radiation therapy has been used to treat cancer; however, the associated DNA damage and adverse effects in the surrounding tissues remain major concerns. In radiation injury, several natural remedies can effectively relieve symptoms with minimal side effects. Cicadidae Periostracum (CP, also called “Sun-Tae”) is the cast-off shell of Cryptotympana pustulata Fabricius and has been traditionally used for several pharmacological actions. This study investigated the protective effects of CP water extract (CPE) on irradiated testicular tissue and spermatogenesis. The chemical constituents of CPE were analyzed using a high-performance liquid chromatography system equipped with a mass detector and were determined to be dimeric N-acetyl dopamine derivatives. The testes and epididymal tissues of male C57BL/6 mice orally pretreated with CPE (25 and 50 mg/kg) 24 h and 15 min before radiation exposure (5 Gy) were collected for analysis. CPE pretreatment ameliorated radiation-induced apoptosis in the testes and inhibited weight loss in the epididymis compared to those of the irradiated group. Treatment with high-dose CPE prevented the radiation-induced decrease in the epithelial height of seminiferous tubules. In addition, the morphology, motility, and number of damaged sperm cells following radiation exposure were alleviated by CPE treatment. Furthermore, the dose-dependent antioxidative activity of CPE was confirmed in 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging assays, and reactive oxygen species generation by hydrogen peroxide was reduced by CPE treatment in vitro. Our findings suggest that pretreatment with CPE can ameliorate testicular tissue damage and sperm degeneration via the antioxidative properties of CPE in radiation-injured testis tissue.

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引用次数: 0
Correction to “Discovery and Verification of Soybean Sprouting Selection Based on Quality Across Various Origins and Varieties: Varietal Effects on Sprouted Soybean Quality”
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-23 DOI: 10.1002/fsn3.70193

Li, M, Zhao, M, Shi, J, Huang, Y, Li, L, Jin, N, Kong, Z, Simal-Gandara, J, Wang, F, Fan, B, Xie, H. Discovery and Verification of Soybean Sprouting Selection Based on Quality Across Various Origins and Varieties: Varietal Effects on Sprouted Soybean Quality. Food Sci. & Nutr. 2025; 13:e70016. https://doi.org/10.1002/fsn3.70016

The author name “Jesus Simal-Gandarad” should be corrected to “Jesus Simal-Gandara” (https://orcid.org/0000-0001-9215-9737). The online version of this article has been corrected accordingly.

We apologize for this error.

Li, M, Zhao, M, Shi, J, Huang, Y, Li, L, Jin, N, Kong, Z, Simal-Gandara, J, Wang, F, Fan, B, Xie, H. Discovery and Verification of Soybean Sprouting Selection Based on Quality Across Various Origins and Varieties:品种对发芽大豆质量的影响。https://doi.org/10.1002/fsn3.70016 作者姓名 "Jesus Simal-Gandarad "应更正为 "Jesus Simal-Gandara"(https://orcid.org/0000-0001-9215-9737)。本文的在线版本已作相应更正。我们对此错误深表歉意。
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引用次数: 0
Optimization of Nutritional and Sensory Properties of Unleavened Flatbread Developed From Maize-Boiled Rhizome of Water Lily—Fish
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-04-22 DOI: 10.1002/fsn3.70192
Alemu Lema Abelti, Tilahun A. Teka, Geremew Bultosa

The aim of this study was to optimize nutritional composition, mineral contents, and overall sensory acceptability of unleavened flatbread developed from maize, boiled rhizome of water lily, and dried fish fillet powder. A mixture containing 50%–80% maize, 15%–30% boiled water lily rhizome, and 5%–20% dried fish fillet powder was mixed using the D-optimal mixture design. Flatbread developed from maize flour was used as the control. The results showed that the linear model described well changes in crude protein, total carbohydrate, gross energy value, sodium, potassium, iron, and zinc. The lack of fit was non-significant (p > 0.05) for all the linear models, indicating that the linear model equations fit the data well. The addition of boiled rhizome of water lily flour and dried fish fillet powder to maize improved protein content, potassium, calcium, magnesium, iron, and zinc but decreased fat, fiber, carbohydrate, and gross energy value. Numerical optimization results showed that a blending ratio containing 62.62% maize, 29.92% boiled rhizome of water lily, and 7.45% dried fish fillet powder resulted in the best formulation with a desirability function value of 0.516. It can be concluded that this bread can potentially reduce protein energy malnutrition and micronutrient deficiencies.

{"title":"Optimization of Nutritional and Sensory Properties of Unleavened Flatbread Developed From Maize-Boiled Rhizome of Water Lily—Fish","authors":"Alemu Lema Abelti,&nbsp;Tilahun A. Teka,&nbsp;Geremew Bultosa","doi":"10.1002/fsn3.70192","DOIUrl":"https://doi.org/10.1002/fsn3.70192","url":null,"abstract":"<p>The aim of this study was to optimize nutritional composition, mineral contents, and overall sensory acceptability of unleavened flatbread developed from maize, boiled rhizome of water lily, and dried fish fillet powder. A mixture containing 50%–80% maize, 15%–30% boiled water lily rhizome, and 5%–20% dried fish fillet powder was mixed using the D-optimal mixture design. Flatbread developed from maize flour was used as the control. The results showed that the linear model described well changes in crude protein, total carbohydrate, gross energy value, sodium, potassium, iron, and zinc. The lack of fit was non-significant (<i>p</i> &gt; 0.05) for all the linear models, indicating that the linear model equations fit the data well. The addition of boiled rhizome of water lily flour and dried fish fillet powder to maize improved protein content, potassium, calcium, magnesium, iron, and zinc but decreased fat, fiber, carbohydrate, and gross energy value. Numerical optimization results showed that a blending ratio containing 62.62% maize, 29.92% boiled rhizome of water lily, and 7.45% dried fish fillet powder resulted in the best formulation with a desirability function value of 0.516. It can be concluded that this bread can potentially reduce protein energy malnutrition and micronutrient deficiencies.</p>","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 4","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70192","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Food Science & Nutrition
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