Pub Date : 2024-10-16eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1453135
Wenqing Han, Yingjie Yan, Mengzhe Sun, Ziwei Zhang, Li Lin, Yan Zhang, Gang Chai
Introduction: This study evaluated the efficacy and learning curve of a maxillofacial surgical robotic system (MSRS) guided by electromagnetic navigation for mandibular angle ostectomy (MAO), compared to traditional surgical methods.
Methods: The study utilized a controlled experiment involving thirty rabbits, paired divided into experimental and control groups. The experimental group underwent MAO using the MSRS, while the control group was treated with conventional surgical techniques. The surgeons performing the procedures were inexperienced in robotic surgery and MAO to assess the learning curve and the impact of robotic assistance. Key parameters measured included the accuracy of ostectomy, setup time, and ostectomy efficiency, with data analyzed through a paired-t test to compare the performance between the two groups.
Results: The study indicated a significant reduction in ostectomy time for the experimental group, with improved accuracy and efficiency in ostectomy. The study found that robotic assistance could decrease the risk of complications and enhance surgical outcomes. It also highlighted the presence of an initial learning curve when adopting new robotic technologies, which could be mitigated through adequate training and simulation practices.
Discussion: Using MSRS for MAO could lead to faster early learning curves and increased ostectomy efficiency compared to traditional surgical methods. It demonstrated the potential benefits of integrating robotic systems into craniofacial surgery, suggesting a promising direction for future surgical practices.
导言:本研究评估了电磁导航引导下颌角切除术(MAO)的颌面外科机器人系统(MSRS)与传统手术方法相比的疗效和学习曲线:研究采用对照实验,将 30 只兔子配对分为实验组和对照组。实验组使用 MSRS 进行 MAO 手术,而对照组则使用传统手术技术。执行手术的外科医生没有机器人手术和 MAO 的经验,以评估学习曲线和机器人辅助的影响。测量的主要参数包括输卵管切除术的准确性、设置时间和输卵管切除术的效率,通过配对t检验分析数据,比较两组的表现:结果:研究表明,实验组的切除术时间明显缩短,切除术的准确性和效率也有所提高。研究发现,机器人辅助可降低并发症风险,提高手术效果。研究还强调,在采用新的机器人技术时,初期学习曲线是存在的,但可以通过适当的培训和模拟练习来缓解这一问题:讨论:与传统手术方法相比,使用MSRS进行MAO手术可加快早期学习曲线,并提高切除术的效率。它证明了将机器人系统整合到颅颌面手术中的潜在好处,为未来的手术实践指明了方向。
{"title":"Evaluating robotic assistance on the learning curve and efficiency of mandibular angle ostectomy: an animal model study.","authors":"Wenqing Han, Yingjie Yan, Mengzhe Sun, Ziwei Zhang, Li Lin, Yan Zhang, Gang Chai","doi":"10.3389/fsurg.2024.1453135","DOIUrl":"10.3389/fsurg.2024.1453135","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated the efficacy and learning curve of a maxillofacial surgical robotic system (MSRS) guided by electromagnetic navigation for mandibular angle ostectomy (MAO), compared to traditional surgical methods.</p><p><strong>Methods: </strong>The study utilized a controlled experiment involving thirty rabbits, paired divided into experimental and control groups. The experimental group underwent MAO using the MSRS, while the control group was treated with conventional surgical techniques. The surgeons performing the procedures were inexperienced in robotic surgery and MAO to assess the learning curve and the impact of robotic assistance. Key parameters measured included the accuracy of ostectomy, setup time, and ostectomy efficiency, with data analyzed through a paired-t test to compare the performance between the two groups.</p><p><strong>Results: </strong>The study indicated a significant reduction in ostectomy time for the experimental group, with improved accuracy and efficiency in ostectomy. The study found that robotic assistance could decrease the risk of complications and enhance surgical outcomes. It also highlighted the presence of an initial learning curve when adopting new robotic technologies, which could be mitigated through adequate training and simulation practices.</p><p><strong>Discussion: </strong>Using MSRS for MAO could lead to faster early learning curves and increased ostectomy efficiency compared to traditional surgical methods. It demonstrated the potential benefits of integrating robotic systems into craniofacial surgery, suggesting a promising direction for future surgical practices.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1462525
Fei Ding, Xin Nie, Yuemei Chen, Minjin Wang, Yong He
Congenital nephrogenic diabetes insipidus (NDI) primarily arises from an X-linked recessive inheritance caused by mutations in the AVPR2 gene, which is responsible for approximately 90% of cases. This condition has an incidence rate of 4-8 per million male live births, with females being much less frequently affected. Symptoms typically manifest shortly after birth, predominantly in males. The key clinical features of NDI include excessive urination (polyuria), compensatory excessive thirst (polydipsia), cognitive impairment, consistently low urine specific gravity, dehydration, and imbalances in electrolyte levels. This case study highlights an unusual occurrence of NDI in a 50-year-old Chinese woman attributed to a mutation in the AVPR2 gene. For more than a year, she had been suffering from excessive urination and severe thirst. The patient, who had undergone surgery for cervical cancer, developed polyuria and hypernatremia postoperatively. Initial laboratory analyses revealed normal blood sodium and chloride levels but reduced urine osmolality and specific gravity. Imaging assessments revealed no irregularities. To validate the diagnosis of NDI, she participated in a water deprivation and vasopressin test. Subsequent genetic tests revealed a thymine (T) to adenine (A) mutation, leading to a missense mutation in the AVPR2 gene. As part of her treatment, she was placed on a low-sodium diet and prescribed oral hydrochlorothiazide and indomethacin for 1 month, resulting in a marked improvement in her symptoms. To the best of our knowledge, this is the first documented case of NDI diagnosed postoperatively in an older female patient with AVPR2 heterozygosity. This case highlights an unusual instance of an X-linked recessive clinical presentation of NDI in an elderly female patient. This study also underscores the importance of conducting water deprivation, vasopressin tests, and genetic testing in establishing the underlying cause for individuals diagnosed with NDI.
先天性肾源性糖尿病(NDI)主要是由 AVPR2 基因突变导致的 X 连锁隐性遗传引起的,约 90% 的病例都是由 AVPR2 基因突变引起的。这种疾病的发病率为每百万活产男性中有 4-8 例,而女性的发病率要低得多。症状通常在出生后不久出现,主要发生在男性身上。NDI 的主要临床特征包括多尿、代偿性多渴、认知障碍、尿比重持续偏低、脱水和电解质水平失衡。本病例研究强调了一名 50 岁中国妇女因 AVPR2 基因突变而导致的 NDI 异常发生。一年多来,她一直受到多尿和严重口渴的困扰。患者曾接受宫颈癌手术,术后出现多尿和高钠血症。初步实验室分析显示血钠和血氯水平正常,但尿渗透压和尿比重降低。影像学评估未发现异常。为了验证 NDI 诊断,她参加了缺水和血管加压素试验。随后的基因检测发现胸腺嘧啶(T)变为腺嘌呤(A),导致 AVPR2 基因发生错义突变。作为治疗的一部分,她接受了低钠饮食,并口服氢氯噻嗪和吲哚美辛 1 个月,症状得到明显改善。据我们所知,这是第一例有记录的术后诊断为 NDI 的 AVPR2 杂合子老年女性患者。本病例凸显了 X 连锁隐性临床表现的 NDI 在老年女性患者中的不寻常病例。这项研究还强调了进行水剥夺、血管加压素测试和基因测试以确定被诊断为 NDI 患者的潜在病因的重要性。
{"title":"Extreme hypernatremia after a laparoscopic hysterectomy and bilateral salpingo-oophorectomy: a case report and literature review.","authors":"Fei Ding, Xin Nie, Yuemei Chen, Minjin Wang, Yong He","doi":"10.3389/fsurg.2024.1462525","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1462525","url":null,"abstract":"<p><p>Congenital nephrogenic diabetes insipidus (NDI) primarily arises from an X-linked recessive inheritance caused by mutations in the <i>AVPR2</i> gene, which is responsible for approximately 90% of cases. This condition has an incidence rate of 4-8 per million male live births, with females being much less frequently affected. Symptoms typically manifest shortly after birth, predominantly in males. The key clinical features of NDI include excessive urination (polyuria), compensatory excessive thirst (polydipsia), cognitive impairment, consistently low urine specific gravity, dehydration, and imbalances in electrolyte levels. This case study highlights an unusual occurrence of NDI in a 50-year-old Chinese woman attributed to a mutation in the <i>AVPR2</i> gene. For more than a year, she had been suffering from excessive urination and severe thirst. The patient, who had undergone surgery for cervical cancer, developed polyuria and hypernatremia postoperatively. Initial laboratory analyses revealed normal blood sodium and chloride levels but reduced urine osmolality and specific gravity. Imaging assessments revealed no irregularities. To validate the diagnosis of NDI, she participated in a water deprivation and vasopressin test. Subsequent genetic tests revealed a thymine (T) to adenine (A) mutation, leading to a missense mutation in the <i>AVPR2</i> gene. As part of her treatment, she was placed on a low-sodium diet and prescribed oral hydrochlorothiazide and indomethacin for 1 month, resulting in a marked improvement in her symptoms. To the best of our knowledge, this is the first documented case of NDI diagnosed postoperatively in an older female patient with <i>AVPR2</i> heterozygosity. This case highlights an unusual instance of an X-linked recessive clinical presentation of NDI in an elderly female patient. This study also underscores the importance of conducting water deprivation, vasopressin tests, and genetic testing in establishing the underlying cause for individuals diagnosed with NDI.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1403668
Yue Tang, Xiangping Zhong, Tingting Lin, Fujun Zuo, Min Fu, Li Wang, Xiaodu Yu, Dong Liu, Jincan Zhang
Objective: Acute aneurysmal rupture can be treated with endovascular therapy or surgical clipping. For patients with concurrent acute hydrocephalus, the placement of an external ventricular drainage (EVD) is required. This study aims to investigate the impact of pre-treatment EVD placement on rebleeding in ruptured aneurysms and to examine the influence of dual antiplatelet therapy and the sequencing of dual antiplatelet therapy with EVD placement on EVD-related hematomas.
Methods: We reviewed the clinical data of 83 patients with ruptured aneurysms who underwent EVD placement from a total of 606 aneurysm patients consecutively admitted between January 2018 and January 2023. The analysis focused on the impact of pre-treatment EVD placement on aneurysmal rebleeding and the effect of dual antiplatelet therapy and its sequencing with EVD placement on EVD-related hematomas.
Results: Among the 503 patients with ruptured aneurysms, 83 required EVD placement. EVD was placed before aneurysm treatment in 63 patients and after treatment in 20 patients. The number of aneurysmal rebleeding cases in the pre-treatment EVD group and non-EVD group was 1 (1.6%) and 20 (4.8%), respectively (p = 0.406). 31 patients (37.3%) underwent stent-assisted embolization or flow diversion requiring dual antiplatelet therapy, while 52 patients (62.7%) underwent simple embolization or surgical clipping without antiplatelet therapy. EVD-related hematomas occurred in 14 patients (16.9%), with 10 cases (32.3%) in those receiving dual antiplatelet therapy and 4 cases (7.7%) in those not receiving antiplatelet therapy (p = 0.01). Among 16 patients who had EVD placed before dual antiplatelet therapy, 4 (25%) developed EVD-related hematomas. Of the 15 patients who had EVD placed after dual antiplatelet therapy, 6 (40%) developed EVD-related hematomas (p = 0.458).
Conclusion: In patients with aneurysmal subarachnoid hemorrhage (aSAH) and acute hydrocephalus, the placement of EVD before aneurysm treatment does not increase the risk of rebleeding. However, dual antiplatelet therapy increases the risk of EVD-related hematoma, and the sequence of EVD placement relative to dual antiplatelet therapy does not appear to significantly affect the outcome of EVD-related hematoma.
{"title":"Bleeding complications related to external ventricular drainage placement in patients with ruptured intracranial aneurysms: a single-center study.","authors":"Yue Tang, Xiangping Zhong, Tingting Lin, Fujun Zuo, Min Fu, Li Wang, Xiaodu Yu, Dong Liu, Jincan Zhang","doi":"10.3389/fsurg.2024.1403668","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1403668","url":null,"abstract":"<p><strong>Objective: </strong>Acute aneurysmal rupture can be treated with endovascular therapy or surgical clipping. For patients with concurrent acute hydrocephalus, the placement of an external ventricular drainage (EVD) is required. This study aims to investigate the impact of pre-treatment EVD placement on rebleeding in ruptured aneurysms and to examine the influence of dual antiplatelet therapy and the sequencing of dual antiplatelet therapy with EVD placement on EVD-related hematomas.</p><p><strong>Methods: </strong>We reviewed the clinical data of 83 patients with ruptured aneurysms who underwent EVD placement from a total of 606 aneurysm patients consecutively admitted between January 2018 and January 2023. The analysis focused on the impact of pre-treatment EVD placement on aneurysmal rebleeding and the effect of dual antiplatelet therapy and its sequencing with EVD placement on EVD-related hematomas.</p><p><strong>Results: </strong>Among the 503 patients with ruptured aneurysms, 83 required EVD placement. EVD was placed before aneurysm treatment in 63 patients and after treatment in 20 patients. The number of aneurysmal rebleeding cases in the pre-treatment EVD group and non-EVD group was 1 (1.6%) and 20 (4.8%), respectively (<i>p</i> = 0.406). 31 patients (37.3%) underwent stent-assisted embolization or flow diversion requiring dual antiplatelet therapy, while 52 patients (62.7%) underwent simple embolization or surgical clipping without antiplatelet therapy. EVD-related hematomas occurred in 14 patients (16.9%), with 10 cases (32.3%) in those receiving dual antiplatelet therapy and 4 cases (7.7%) in those not receiving antiplatelet therapy (<i>p</i> = 0.01). Among 16 patients who had EVD placed before dual antiplatelet therapy, 4 (25%) developed EVD-related hematomas. Of the 15 patients who had EVD placed after dual antiplatelet therapy, 6 (40%) developed EVD-related hematomas (<i>p</i> = 0.458).</p><p><strong>Conclusion: </strong>In patients with aneurysmal subarachnoid hemorrhage (aSAH) and acute hydrocephalus, the placement of EVD before aneurysm treatment does not increase the risk of rebleeding. However, dual antiplatelet therapy increases the risk of EVD-related hematoma, and the sequence of EVD placement relative to dual antiplatelet therapy does not appear to significantly affect the outcome of EVD-related hematoma.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1469847
Jiana Hong, Xiaodan Mao
Background: Tunneled peripherally inserted central catheters (PICC) have potential to reduce complications compared to non-tunneled PICC in previous studies. Which is better is debatable. Thus, the aim to compare the effect of tunneled and non-tunneled PICC for cancer patients undergoing chemotherapy.
Methods: Embase, PubMed, Cochrane Library database, and CNKI were searched from inception to March 15, 2024. Odds ratios (ORs) with 95% confidence intervals (95% CIs) was calculated to assess the complications of tunneled and non-tunneled PICC for cancer patients undergoing chemotherapy using random- or fixed-effects models.
Results: A total of 12 articles were retrieved. Meta-analysis showed that tunneled PICC significantly decreased the risk of wound oozing (OR: 0.29, 95% CI: 0.20-0.41), infection risk (OR: 0.41, 95% CI: 0.20-0.85), thrombosis risk (OR: 0.26, 95% CI: 0.15-0.44), phlebitis risk (OR: 0.23, 95% CI: 0.13-0.40), and catheter dislodgement risk (OR: 0.33, 95% CI: 0.22-0.50) compared to non-tunneled PICC.
Conclusions: The subcutaneous tunneling technology has advantages over normal technique in decreasing PICC-related complications for cancer patients undergoing chemotherapy.
{"title":"Complications of tunneled and non-tunneled peripherally inserted central catheter placement in chemotherapy-treated cancer patients: a meta-analysis.","authors":"Jiana Hong, Xiaodan Mao","doi":"10.3389/fsurg.2024.1469847","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1469847","url":null,"abstract":"<p><strong>Background: </strong>Tunneled peripherally inserted central catheters (PICC) have potential to reduce complications compared to non-tunneled PICC in previous studies. Which is better is debatable. Thus, the aim to compare the effect of tunneled and non-tunneled PICC for cancer patients undergoing chemotherapy.</p><p><strong>Methods: </strong>Embase, PubMed, Cochrane Library database, and CNKI were searched from inception to March 15, 2024. Odds ratios (ORs) with 95% confidence intervals (95% CIs) was calculated to assess the complications of tunneled and non-tunneled PICC for cancer patients undergoing chemotherapy using random- or fixed-effects models.</p><p><strong>Results: </strong>A total of 12 articles were retrieved. Meta-analysis showed that tunneled PICC significantly decreased the risk of wound oozing (OR: 0.29, 95% CI: 0.20-0.41), infection risk (OR: 0.41, 95% CI: 0.20-0.85), thrombosis risk (OR: 0.26, 95% CI: 0.15-0.44), phlebitis risk (OR: 0.23, 95% CI: 0.13-0.40), and catheter dislodgement risk (OR: 0.33, 95% CI: 0.22-0.50) compared to non-tunneled PICC.</p><p><strong>Conclusions: </strong>The subcutaneous tunneling technology has advantages over normal technique in decreasing PICC-related complications for cancer patients undergoing chemotherapy.</p><p><strong>Systematic review registration: </strong>PROSPERO (CRD42024522862).</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1446792
Calogero Velluto, Gregory Mundis, Laura Scaramuzzo, Andrea Perna, Giacomo Capece, Andrea Cruciani, Michele Inverso, Maria Ilaria Borruto, Luca Proietti
Introduction: The assessment of segmental fusion after Lateral Lumbar Interbody fusion (LLIF) using 3D-printed porous titanium cage is still not well studied. Various criteria, such as the presence of bone bridges (BB) between adjacent vertebrae, serve as indicators for anterior fusion. However, limited radiological studies have investigated zygapophyseal joints (ZJ) status following LLIF with porous titanium cages vs. conventional titanium threaded cages. The porous design of the latest titanium intervertebral cages is thought to enhance the bone-to-implant fusion rate. This radiological study aimed to compare the fusion patterns post-LLIF using 3D-printed porous titanium cages against those using threaded titanium cages. This radiological study aimed to compare the fusion patterns after LLIF using 3D-printed porous titanium cages against those using threaded titanium cages.
Material and methods: This retrospective, single-center radiological study involved 135 patients who underwent LLIF and posterior percutaneous screw fixation for degenerative spondylolisthesis. The study included 51 patients (Group A) with the novel porous titanium cages and 84 patients (Group B) with conventional threaded titanium cages. Inclusion criteria mandated complete radiological data and a minimum follow-up period of 24 months. The study evaluated intervertebral bone bridges (BB) for anterior fusion and zygapophyseal joints (ZJ) ankylotic degeneration, based on Pathria et al., as evidence of posterior fusion and segmental immobilization.
Results: Two years after surgery, intervertebral BB were identified in 83 segments (94.31%) in Group A and in 87 segments (88.77%) in Group B. ZJ Pathria grade I was observed in 2 segments (2.27%) of Group A and in 4 segments (4.08%) of Group B. Grade II was seen in 5 segments (5.68%) of Group A and in 6 segments (6.12%) of Group B. Posterior fusion, classified as grade III, was found in 81 segments (92.04%) of Group A and 88 segments (89.79%) of Group B. Subsidence incidence was 5.88% (3 segments) for the novel cage and 9.88% (8 segments) for the conventional cage.
Conclusions: The architecture of porous titanium cages offers a promising solution for increasing bone ingrowth and bridging space, supporting successful spinal fusion while minimizing the risk of subsidence.
{"title":"Radiological evaluation of fusion patterns after Lateral Lumbar Interbody fusion with 3D-printed porous titanium cages vs. conventional titanium cages.","authors":"Calogero Velluto, Gregory Mundis, Laura Scaramuzzo, Andrea Perna, Giacomo Capece, Andrea Cruciani, Michele Inverso, Maria Ilaria Borruto, Luca Proietti","doi":"10.3389/fsurg.2024.1446792","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1446792","url":null,"abstract":"<p><strong>Introduction: </strong>The assessment of segmental fusion after Lateral Lumbar Interbody fusion (LLIF) using 3D-printed porous titanium cage is still not well studied. Various criteria, such as the presence of bone bridges (BB) between adjacent vertebrae, serve as indicators for anterior fusion. However, limited radiological studies have investigated zygapophyseal joints (ZJ) status following LLIF with porous titanium cages vs. conventional titanium threaded cages. The porous design of the latest titanium intervertebral cages is thought to enhance the bone-to-implant fusion rate. This radiological study aimed to compare the fusion patterns post-LLIF using 3D-printed porous titanium cages against those using threaded titanium cages. This radiological study aimed to compare the fusion patterns after LLIF using 3D-printed porous titanium cages against those using threaded titanium cages.</p><p><strong>Material and methods: </strong>This retrospective, single-center radiological study involved 135 patients who underwent LLIF and posterior percutaneous screw fixation for degenerative spondylolisthesis. The study included 51 patients (Group A) with the novel porous titanium cages and 84 patients (Group B) with conventional threaded titanium cages. Inclusion criteria mandated complete radiological data and a minimum follow-up period of 24 months. The study evaluated intervertebral bone bridges (BB) for anterior fusion and zygapophyseal joints (ZJ) ankylotic degeneration, based on Pathria et al., as evidence of posterior fusion and segmental immobilization.</p><p><strong>Results: </strong>Two years after surgery, intervertebral BB were identified in 83 segments (94.31%) in Group A and in 87 segments (88.77%) in Group B. ZJ Pathria grade I was observed in 2 segments (2.27%) of Group A and in 4 segments (4.08%) of Group B. Grade II was seen in 5 segments (5.68%) of Group A and in 6 segments (6.12%) of Group B. Posterior fusion, classified as grade III, was found in 81 segments (92.04%) of Group A and 88 segments (89.79%) of Group B. Subsidence incidence was 5.88% (3 segments) for the novel cage and 9.88% (8 segments) for the conventional cage.</p><p><strong>Conclusions: </strong>The architecture of porous titanium cages offers a promising solution for increasing bone ingrowth and bridging space, supporting successful spinal fusion while minimizing the risk of subsidence.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1487567
Shiwei Xie, Mingwei Luo, Heng Xiao
Lumbar disc herniation (LDH) is a prevalent condition that severely impacts patients' quality of life and work capacity. Traditional surgical treatments like laminectomy, while effective, involve significant invasiveness and potential complications, including long-term spinal instability and recurrent symptoms. With the advancement of minimally invasive techniques, percutaneous endoscopic lumbar discectomy (PELD) has become a popular option due to its reduced trauma and faster recovery. However, PELD, while beneficial, carries risks, including complications that may not be immediately evident. This report presents the case of a 60-year-old female patient who underwent PELD for L4/5 disc herniation but experienced significant postoperative complications, including increased pain and neurological symptoms. Initial conservative management failed, and further investigations suggested possible postoperative infection, though this was later ruled out through surgical exploration and bacterial cultures. The patient subsequently underwent open surgical exploration, which revealed extensive tissue damage and required additional interventions, including a minimally invasive lateral anterior approach for stabilization and fusion (MIS-OLIF). Postoperative recovery was successful, with complete symptom resolution and stable spine alignment at a six-month follow-up. This case highlights the complexity of managing PELD-related complications and underscores the importance of thorough diagnostic evaluation and the potential need for additional surgical interventions to ensure long-term patient outcomes.
{"title":"Dural tears with cauda equina herniation following percutaneous endoscopic lumbar discectomy: a case report and literature review.","authors":"Shiwei Xie, Mingwei Luo, Heng Xiao","doi":"10.3389/fsurg.2024.1487567","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1487567","url":null,"abstract":"<p><p>Lumbar disc herniation (LDH) is a prevalent condition that severely impacts patients' quality of life and work capacity. Traditional surgical treatments like laminectomy, while effective, involve significant invasiveness and potential complications, including long-term spinal instability and recurrent symptoms. With the advancement of minimally invasive techniques, percutaneous endoscopic lumbar discectomy (PELD) has become a popular option due to its reduced trauma and faster recovery. However, PELD, while beneficial, carries risks, including complications that may not be immediately evident. This report presents the case of a 60-year-old female patient who underwent PELD for L4/5 disc herniation but experienced significant postoperative complications, including increased pain and neurological symptoms. Initial conservative management failed, and further investigations suggested possible postoperative infection, though this was later ruled out through surgical exploration and bacterial cultures. The patient subsequently underwent open surgical exploration, which revealed extensive tissue damage and required additional interventions, including a minimally invasive lateral anterior approach for stabilization and fusion (MIS-OLIF). Postoperative recovery was successful, with complete symptom resolution and stable spine alignment at a six-month follow-up. This case highlights the complexity of managing PELD-related complications and underscores the importance of thorough diagnostic evaluation and the potential need for additional surgical interventions to ensure long-term patient outcomes.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1329085
Ata Jodeiri, Hadi Seyedarabi, Parmida Shahbazi, Fatemeh Shahbazi, Seyed Mohammad Mahdi Hashemi, Seyed Mohammad Javad Mortazavi, Seyyed Hossein Shafiei
Introduction: This study presents the development and validation of a Deep Learning Convolutional Neural Network (CNN) model for estimating acetabular version (AV) from native hip plain radiographs.
Methods: Utilizing a dataset comprising 300 participants with unrelated pelvic complaints, the CNN model was trained and evaluated against CT-Scans, considered the gold standard, using a 5-fold cross-validation.
Results: Notably, the CNN model exhibited a robust performance, demonstrating a strong Pearson correlation with CT-Scans (right hip: r = 0.70, p < 0.001; left hip: r = 0.71, p < 0.001) and achieving a mean absolute error of 2.95°. Remarkably, over 83% of predictions yielded errors ≤5°, highlighting the model's high precision in AV estimation.
Discussion: The model holds promise in preoperative planning for hip arthroplasty, potentially reducing complications like recurrent dislocation and component wear. Future directions include further refinement of the CNN model, with ongoing investigations aimed at enhancing preoperative planning potential and ensuring comprehensive assessment across diverse patient populations, particularly in diseased cases. Additionally, future research could explore the model's potential value in scenarios necessitating minimized ionizing radiation exposure, such as post-operative evaluations.
{"title":"Predicting acetabular version in native hip joints through plain x-ray radiographs: a comparative analysis of convolutional neural network model and the current gold standard, with insights and implications for hip arthroplasty.","authors":"Ata Jodeiri, Hadi Seyedarabi, Parmida Shahbazi, Fatemeh Shahbazi, Seyed Mohammad Mahdi Hashemi, Seyed Mohammad Javad Mortazavi, Seyyed Hossein Shafiei","doi":"10.3389/fsurg.2024.1329085","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1329085","url":null,"abstract":"<p><strong>Introduction: </strong>This study presents the development and validation of a Deep Learning Convolutional Neural Network (CNN) model for estimating acetabular version (AV) from native hip plain radiographs.</p><p><strong>Methods: </strong>Utilizing a dataset comprising 300 participants with unrelated pelvic complaints, the CNN model was trained and evaluated against CT-Scans, considered the gold standard, using a 5-fold cross-validation.</p><p><strong>Results: </strong>Notably, the CNN model exhibited a robust performance, demonstrating a strong Pearson correlation with CT-Scans (right hip: <i>r</i> = 0.70, <i>p</i> < 0.001; left hip: <i>r</i> = 0.71, <i>p</i> < 0.001) and achieving a mean absolute error of 2.95°. Remarkably, over 83% of predictions yielded errors ≤5°, highlighting the model's high precision in AV estimation.</p><p><strong>Discussion: </strong>The model holds promise in preoperative planning for hip arthroplasty, potentially reducing complications like recurrent dislocation and component wear. Future directions include further refinement of the CNN model, with ongoing investigations aimed at enhancing preoperative planning potential and ensuring comprehensive assessment across diverse patient populations, particularly in diseased cases. Additionally, future research could explore the model's potential value in scenarios necessitating minimized ionizing radiation exposure, such as post-operative evaluations.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-14eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1477023
Andrea Vittorio Emanuele Lisa, Flavia Zeneli, Martina Mazzucco, Benedetta Barbieri, Mario Rietjens, Germana Lissidini, Valeriano Vinci, Michele Bartoletti, Alessandra Belati, Davide Bavaro
Introduction: Implant-based breast reconstruction (IBR) is the predominant breast reconstruction technique post-mastectomy, with bacterial infections being a significant complication affecting patient recovery and quality of life. The following study aimed to determine the microbiological features of the causative agents responsible for breast implant infections, with more attention paid to the comparative analysis of Gram-positive and Gram-negative bacteria and their presentation.
Methods: We conducted a retrospective analysis of 214 patients who presented with periprosthetic infection and underwent implant removal following implant-based breast reconstruction at Humanitas Research Hospital and Istituto Europeo di Oncologia between January 2018 and March 2024.
Results: The study revealed that Gram-positive bacteria were more prevalent, with Staphylococcus species, particularly Staphylococcus aureus, being the most isolated pathogen in both institutions (∼39.96%). In contrast, Gram-negative bacteria were less frequent, with a higher proportion of these pathogens being multi-resistant strains. A significant difference was observed (p = 0.007), indicating that individuals with normal BMI have a higher prevalence of Gram-positive infections (88.46%), whereas obese and overweight patients had higher proportions of Gram-negative infections (23.53% and 28.89%, respectively). In addition, smoking status was also significantly associated with pathogen distribution (p = 0.032), with active and past smokers being related to higher percentages of polymicrobial infections. Furthermore, positive prophylactic MSSA/MRSA swabs were significantly more associated with Staphylococcus aureus infections compared to those with negative results (p = <0.001).
Conclusions: Gram-positive bacteria, especially Staphylococcus species, dominate the microbiological landscape of implant-based breast reconstruction (IBR) infections. Our findings provide insights into this critical issue, facilitating a more precise choice of empiric antibiotic treatment and prevention strategies. This analysis underscores the necessity for prophylactic protocols and therapeutic approaches tailored to the predominant bacterial groups. Further research is needed to explore long-term trends and resistance mechanisms to improve patient management.
{"title":"Microbiology of periprosthetic infections following implant-based breast reconstruction surgery: a multicentric retrospective study.","authors":"Andrea Vittorio Emanuele Lisa, Flavia Zeneli, Martina Mazzucco, Benedetta Barbieri, Mario Rietjens, Germana Lissidini, Valeriano Vinci, Michele Bartoletti, Alessandra Belati, Davide Bavaro","doi":"10.3389/fsurg.2024.1477023","DOIUrl":"10.3389/fsurg.2024.1477023","url":null,"abstract":"<p><strong>Introduction: </strong>Implant-based breast reconstruction (IBR) is the predominant breast reconstruction technique post-mastectomy, with bacterial infections being a significant complication affecting patient recovery and quality of life. The following study aimed to determine the microbiological features of the causative agents responsible for breast implant infections, with more attention paid to the comparative analysis of Gram-positive and Gram-negative bacteria and their presentation.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 214 patients who presented with periprosthetic infection and underwent implant removal following implant-based breast reconstruction at Humanitas Research Hospital and Istituto Europeo di Oncologia between January 2018 and March 2024.</p><p><strong>Results: </strong>The study revealed that Gram-positive bacteria were more prevalent, with <i>Staphylococcus</i> species, particularly <i>Staphylococcus aureus</i>, being the most isolated pathogen in both institutions (∼39.96%). In contrast, Gram-negative bacteria were less frequent, with a higher proportion of these pathogens being multi-resistant strains. A significant difference was observed (<i>p</i> = 0.007), indicating that individuals with normal BMI have a higher prevalence of Gram-positive infections (88.46%), whereas obese and overweight patients had higher proportions of Gram-negative infections (23.53% and 28.89%, respectively). In addition, smoking status was also significantly associated with pathogen distribution (<i>p</i> = 0.032), with active and past smokers being related to higher percentages of polymicrobial infections. Furthermore, positive prophylactic MSSA/MRSA swabs were significantly more associated with <i>Staphylococcus aureus</i> infections compared to those with negative results (<i>p</i> = <0.001).</p><p><strong>Conclusions: </strong>Gram-positive bacteria, especially <i>Staphylococcus</i> species, dominate the microbiological landscape of implant-based breast reconstruction (IBR) infections. Our findings provide insights into this critical issue, facilitating a more precise choice of empiric antibiotic treatment and prevention strategies. This analysis underscores the necessity for prophylactic protocols and therapeutic approaches tailored to the predominant bacterial groups. Further research is needed to explore long-term trends and resistance mechanisms to improve patient management.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-14eCollection Date: 2024-01-01DOI: 10.3389/fsurg.2024.1487878
M P Dimopoulos, G I Verras, F Mulita
{"title":"Editorial: Newest challenges and advances in the treatment of colorectal disorders; from predictive biomarkers to minimally invasive techniques.","authors":"M P Dimopoulos, G I Verras, F Mulita","doi":"10.3389/fsurg.2024.1487878","DOIUrl":"10.3389/fsurg.2024.1487878","url":null,"abstract":"","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}