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Diagnostic performance of digital tomosynthesis for postoperative assessment of acetabular fractures and pelvic ring injuries. 数字断层扫描在髋臼骨折和骨盆环损伤术后评估中的诊断性能。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1461144
Atticus Coscia, Eric Schweppe, Jason Anari, Bruce Kneeland, Annamarie Horan, Samir Mehta, Jaimo Ahn

Introduction: Digital tomosynthesis (DTS) has broad non-orthopaedic applications and has seen limited use within orthopaedics for imaging of the wrist. The utility of DTS for assessing reduction and hardware placement following operative treatment of pelvic ring injuries and acetabular fractures has not previously been investigated.

Methods: All operatively treated acetabular fractures and pelvic ring injuries that underwent surgical fixation within a one-year time span received both a computed tomography (CT) scan and a DTS scan as part of their routine postoperative imaging workup. Three orthopaedic traumatologists independently reviewed the images for face-value clinical utility. Radimetrics and PCXMC software were utilized on a subset of the study population's DTS and CT studies to calculate the effective and organ radiation doses delivered.

Results: 52 patients (22 acetabular fractures, 22 pelvic ring injuries, 7 pelvic ring and acetabular fractures, 2 femoral head & acetabular fractures) were included. DTS was considered adequate to assess reduction 83% of the time, hardware position 83% of the time, and sufficient to replace the CT scan 67% of the time. DTS was associated with an 8.3 times lower effective radiation dose than CT. All organ doses were lower for DTS than CT.

Discussion: DTS appears to have face-value clinical utility for assessing reduction and hardware position following surgical treatment of acetabular fractures and pelvic ring injuries. Given that DTS is associated with significantly lower radiation doses to patients, further study utilizing more objective criteria is warranted.

简介:数字断层扫描(DTS)在非骨科领域应用广泛,但在骨科领域对腕部成像的应用有限。DTS 用于评估骨盆环损伤和髋臼骨折手术治疗后的复位和硬件置放情况的实用性此前尚未进行过研究:方法:所有在一年时间内接受手术固定治疗的髋臼骨折和骨盆环损伤患者均接受了计算机断层扫描(CT)和 DTS 扫描,作为术后常规成像检查的一部分。三位创伤骨科专家独立审查了图像的临床实用价值。利用 Radimetrics 和 PCXMC 软件对研究人群的部分 DTS 和 CT 研究结果进行分析,以计算有效辐射剂量和器官辐射剂量:共纳入 52 名患者(22 例髋臼骨折、22 例骨盆环损伤、7 例骨盆环和髋臼骨折、2 例股骨头和髋臼骨折)。在 83% 的情况下,DTS 被认为足以评估复位情况;在 83% 的情况下,DTS 被认为足以评估硬件位置;在 67% 的情况下,DTS 被认为足以替代 CT 扫描。DTS 的有效辐射剂量比 CT 低 8.3 倍。DTS的所有器官剂量均低于CT:讨论:DTS似乎在评估髋臼骨折和骨盆环损伤手术治疗后的复位和硬件位置方面具有临床实用价值。鉴于DTS对患者的辐射剂量明显较低,有必要利用更客观的标准进行进一步研究。
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引用次数: 0
Development of a predictive model for assessing the risk factors associated with recurrence following surgical treatment of chronic subdural hematoma. 开发一个预测模型,用于评估慢性硬膜下血肿手术治疗后复发的相关风险因素。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1429128
Min Chen, Longbiao Da, Qingchao Zhang, Jie Liu, Jian Tang, Zhengjiang Zha

Background: Chronic subdural hematoma (CSDH) is a common disease in neurosurgery. Although many studies have investigated the factors affecting the recurrence of CSDH, no comprehensive prediction model has been established for the risk effect of postoperative recurrence of the disease.

Objective: This study aims to collect and analyze the data of CSDH patients treated in our hospital to determine the influence of preoperative, postoperative and treatment factors on the recurrence of CSDH, and to establish a corresponding prediction model to provide neurosurgeons with more accurate basis for identifying high-risk patients and guiding treatment.

Methods: A total of 431 patients were collected in this study, including 323 patients who underwent traditional hematoma removal and 108 patients who underwent endoscopic hematoma removal. Relevant preoperative and postoperative data and medical history of patients were collected respectively to study the relevant factors affecting postoperative hematoma recurrence of patients, and to establish a prediction model.

Results: A total of 431 patients were enrolled in this study, 71 of whom had subdural blood recurrence. Possible relevant factors were included in univariate logistic regression, and the results showed that the preoperative GCS score, postoperative residual gas, preoperative CT hematoma thickness, coagulation function, unilateral and bilateral surgery, whether statin was taken after surgery, hematoma site, hematoma density and hematoma volume were all P < 0.2. It is a risk factor for recurrence of chronic subdural hematoma. The obtained data were further included in a multi-factor review. Six factors, including preoperative GCS score, postoperative gas residual, abnormal coagulation function, high-density hematoma, large hematoma volume, and irregular statin use after surgery, were independent risk factors for chronic subdural hematoma recurrence (P < 0.05).

Conclusion: This study confirmed that six factors, including preoperative GCS score, postoperative gas residual, abnormal coagulation function, high-density hematoma, large hematoma volume, and irregular statin use, were independent risk factors for recurrence of chronic subdural hematoma. At the same time, long-term use of statins can reduce the recurrence rate of hematoma to a certain extent. In addition, the predictive model in this study could help neurosurgeons accurately identify high-risk CSDH patients.

背景:慢性硬膜下血肿(CSDH)是神经外科的常见病。尽管许多研究都对影响 CSDH 复发的因素进行了调查,但目前还没有针对该疾病术后复发风险影响的综合预测模型:本研究旨在收集和分析在我院接受治疗的CSDH患者的资料,以确定术前、术后及治疗因素对CSDH复发的影响,并建立相应的预测模型,为神经外科医生识别高危患者和指导治疗提供更准确的依据:本研究共收集了 431 例患者,其中 323 例患者接受了传统血肿清除术,108 例患者接受了内镜下血肿清除术。分别收集患者术前、术后的相关数据和病史,研究影响患者术后血肿复发的相关因素,并建立预测模型:本研究共纳入 431 例患者,其中 71 例硬膜下血肿复发。将可能的相关因素纳入单变量逻辑回归,结果显示术前 GCS 评分、术后残余气体、术前 CT 血肿厚度、凝血功能、单侧和双侧手术、术后是否服用他汀类药物、血肿部位、血肿密度和血肿体积均为 P P 结论:本研究证实,术前 GCS 评分、术后气体残留、凝血功能异常、高密度血肿、血肿体积大、不规则服用他汀类药物等六个因素是慢性硬膜下血肿复发的独立危险因素。同时,长期服用他汀类药物可在一定程度上降低血肿复发率。此外,本研究中的预测模型可以帮助神经外科医生准确识别高风险的 CSDH 患者。
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引用次数: 0
Case Report: Osteosynthesis-associated infection with Ochrobactrum intermedium after acetabular fracture. 病例报告:髋臼骨折后骨关节假体相关的中间赭菌感染。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1382564
David Richard Krueger, Karl-Dieter Heller, Andrej Trampuz, Stefan Weenders

Ochrobactrum intermedium (O. intermedium) is a gram-negative, non-fermenting bacterium closely related to Brucella genus. O. intermedium resembles an emergent human pathogen that has rarely been detected in both immunocompetent and immunodeficient patients. A musculoskeletal infection with O. intermedium has not been described in the literature. We present the first case of an osteosynthesis-associated infection (OAI) with O. intermedium in an 80-year-old female patient after osteosynthesis of an acetabular fracture. The patient was admitted to the emergency department 6 months after osteosynthesis of a posterior column acetabular fracture treated via open reduction and internal plate fixation of the posterior column. The patient demonstrated tenderness, redness and swelling at the insertion site as well as a fistula. The radiological controls showed femoral head necrosis and partial protrusion of the head into the pelvis. The laboratory parameters showed no pathological findings. OAI was assumed and a two-stage revision with implant removal and resection arthroplasty in the first stage and hip arthroplasty in the second stage was performed. All microbiological specimens taken at the osteosynthesis site and the hip joint grew O. intermedium. The pathogen was determined using the matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) method. Antibiotic regime consisted of intravenous (IV) meropenem for two weeks followed by oral ciprofloxacin and cotrimoxazole. Implantation of the hip prosthesis was performed 6 weeks after the index surgery using a cementless revision cup and a cemented stem. Meropenem and vancomycin IV were given for one week followed by ciprofloxacin and doxycycline for another 5 weeks. 24 months after the surgery, the patient is infection free and satisfied with the result. With this case report we would like to increase awareness of possible implant-associated bacterial infections caused by O. intermedium.

Ochrobactrum intermedium(O. intermedium)是一种与布鲁氏菌属密切相关的革兰氏阴性非发酵细菌。O.intermedium类似于一种新出现的人类病原体,在免疫功能正常和免疫缺陷患者中都很少被检测到。文献中尚未描述过O. intermedium引起的肌肉骨骼感染。我们介绍了第一例髋臼骨折骨合成术后感染 O. intermedium 的骨合成术相关感染(OAI)病例,患者是一名 80 岁的女性。患者是在髋臼后柱骨折骨合成术后 6 个月,通过开放复位术和后柱钢板内固定术接受治疗后被送入急诊科的。患者插入部位出现触痛、红肿和瘘管。放射学检查显示股骨头坏死,部分股骨头突入骨盆。实验室参数未显示病理结果。假定患者为 OAI,并进行了两阶段的翻修,第一阶段是移除植入物和切除关节成形术,第二阶段是髋关节成形术。在骨合成部位和髋关节采集的所有微生物标本中都生长出了O. intermedium。病原体采用基质辅助激光解吸/电离飞行时间(MALDI-TOF)法进行测定。抗生素治疗包括静脉注射美罗培南两周,然后口服环丙沙星和复方新诺明。髋关节假体植入在指数手术后6周进行,使用无骨水泥翻修杯和骨水泥柄。美罗培南和万古霉素静脉注射一周,然后环丙沙星和强力霉素再注射5周。术后 24 个月,患者没有发生感染,对手术效果非常满意。通过本病例报告,我们希望提高人们对O.intermedium可能引起的种植体相关细菌感染的认识。
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引用次数: 0
Development of patient-tailored preoperative assessment of percutaneous vertebroplasty. 为患者量身定制经皮椎体成形术术前评估。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1444817
Yian Lu, Qunhua Jiang

Percutaneous vertebroplasty (PVP), a minimally invasive surgery technique, has become the common treatment for osteoporotic vertebral compression fractures (OVCF). The complications of PVP will lead to severe damage to spinal neuro systems due to bone cement leakage. A patient tailored preoperative assessment approach was developed to reduce the risks of complications in this study. The porcine OVCF model was fabricated to mimic the patient vertebral fracture in vitro using decalcification process. The 3D reconstructed model based on the imagological examination data acquired from the porcine vertebral bone was implemented for finite element (FE) simulation. The vertebral body with bone cement injected was scanned using CT for comparison with the finite element simulation results. This study showed a practical method for predicting the flow of bone cement in OVCF, which enabled the surgeons to evaluate the bone cement flow during preoperative assessment to reduce the cement leakage risks.

经皮椎体成形术(PVP)是一种微创手术技术,已成为治疗骨质疏松性椎体压缩骨折(OVCF)的常用方法。经皮椎体成形术的并发症会导致骨水泥渗漏,严重损害脊髓神经系统。本研究开发了一种为患者量身定制的术前评估方法,以降低并发症的风险。猪 OVCF 模型是通过脱钙过程在体外模拟患者椎体骨折而制作的。根据从猪椎骨获取的成像检查数据重建的三维模型被用于有限元(FE)模拟。使用 CT 扫描注入骨水泥的椎体,以便与有限元模拟结果进行比较。这项研究展示了一种预测骨水泥在 OVCF 中流动的实用方法,使外科医生能够在术前评估中评估骨水泥的流动情况,从而降低骨水泥渗漏的风险。
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引用次数: 0
Coverage of large soft tissue defects of the lower limb and foot with superficial inferior epigastric artery flap. 用上腹部浅下动脉皮瓣覆盖下肢和足部大面积软组织缺损。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1424681
Dong Liu, Xingwen Xie, Ping An Chu, Xin Zhou, Lin Luo, Ning Li

Background: Large soft tissue defects of the lower limb and foot are common occurrence in clinical practice and a considerable number of flaps have been used to treat them. However, there have been few reports using the superficial inferior epigastric artery (SIEA) flap. This review aims to present the experience of using the SIEA flaps for the repair of large soft tissue defects of the lower limb and foot.

Methods: A retrospective review of data from 11 patients who underwent coverage of lower limb and foot defects exceeding 120 cm2 (15 × 9 cm) using SIEA flaps from March 2018 to July 2022 were retrospectively reviewed. The average size of the defects was 18 × 11 cm2 (range 15 × 9 cm2-32 × 16 cm2). Flap survival rates, surgical complications and overall long-term outcomes were recorded.

Results: All 11 flaps survived. One flap was partially necrotic at the edge and healed after several changes of dressing. Additionally, one flap presented with mild venous congestion. The mean follow-up period was 18 months (ranging from 12 to 30 months). The mean size of the flaps was 20 × 12 cm2 (range 17 × 9 cm2-34 × 18 cm2). The flaps were observed to be aesthetically pleasing and exhibited a well-defined texture. The donor wounds were successfully closed primarily, with only linear scarring remaining.

Conclusions: The SIEA flap is characterised by concealed donor area, superficial vascular location, easy access and primary closure, which results in favourable aesthetic outcomes. It is an appropriate choice for the repair of large soft tissue defects of the lower limb and foot.

背景:下肢和足部大面积软组织缺损是临床上的常见病,已有大量皮瓣用于治疗。然而,使用上腹部浅下动脉(SIEA)皮瓣的报道却很少。本综述旨在介绍使用上腹部浅动脉皮瓣修复下肢和足部大面积软组织缺损的经验:回顾性回顾了2018年3月至2022年7月期间使用SIEA皮瓣覆盖超过120平方厘米(15 × 9厘米)的下肢和足部缺损的11例患者的数据。缺损的平均大小为 18 × 11 cm2(范围为 15 × 9 cm2-32 × 16 cm2)。记录了皮瓣存活率、手术并发症和总体长期疗效:结果:11 个皮瓣全部存活。结果:11 个皮瓣全部存活,其中一个皮瓣边缘部分坏死,经多次换药后愈合。此外,一个皮瓣出现轻度静脉充血。平均随访时间为 18 个月(从 12 个月到 30 个月不等)。皮瓣的平均大小为 20 × 12 cm2(范围为 17 × 9 cm2-34 × 18 cm2)。据观察,皮瓣外形美观,纹理清晰。供体伤口已成功闭合,仅残留线状瘢痕:SIEA皮瓣的特点是供区隐蔽、血管位置表浅、易于取材和初次闭合,因此具有良好的美学效果。它是修复下肢和足部大面积软组织缺损的合适选择。
{"title":"Coverage of large soft tissue defects of the lower limb and foot with superficial inferior epigastric artery flap.","authors":"Dong Liu, Xingwen Xie, Ping An Chu, Xin Zhou, Lin Luo, Ning Li","doi":"10.3389/fsurg.2024.1424681","DOIUrl":"10.3389/fsurg.2024.1424681","url":null,"abstract":"<p><strong>Background: </strong>Large soft tissue defects of the lower limb and foot are common occurrence in clinical practice and a considerable number of flaps have been used to treat them. However, there have been few reports using the superficial inferior epigastric artery (SIEA) flap. This review aims to present the experience of using the SIEA flaps for the repair of large soft tissue defects of the lower limb and foot.</p><p><strong>Methods: </strong>A retrospective review of data from 11 patients who underwent coverage of lower limb and foot defects exceeding 120 cm<sup>2</sup> (15 × 9 cm) using SIEA flaps from March 2018 to July 2022 were retrospectively reviewed. The average size of the defects was 18 × 11 cm<sup>2</sup> (range 15 × 9 cm<sup>2</sup>-32 × 16 cm<sup>2</sup>). Flap survival rates, surgical complications and overall long-term outcomes were recorded.</p><p><strong>Results: </strong>All 11 flaps survived. One flap was partially necrotic at the edge and healed after several changes of dressing. Additionally, one flap presented with mild venous congestion. The mean follow-up period was 18 months (ranging from 12 to 30 months). The mean size of the flaps was 20 × 12 cm<sup>2</sup> (range 17 × 9 cm<sup>2</sup>-34 × 18 cm<sup>2</sup>). The flaps were observed to be aesthetically pleasing and exhibited a well-defined texture. The donor wounds were successfully closed primarily, with only linear scarring remaining.</p><p><strong>Conclusions: </strong>The SIEA flap is characterised by concealed donor area, superficial vascular location, easy access and primary closure, which results in favourable aesthetic outcomes. It is an appropriate choice for the repair of large soft tissue defects of the lower limb and foot.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1424681"},"PeriodicalIF":1.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Streamlining management in thoracic trauma: radiomics- and AI-based assessment of patient risks. 简化胸部创伤的管理:基于放射影像学和人工智能的患者风险评估。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1462692
Ashraf F Hefny, Taleb M Almansoori, Darya Smetanina, Daria Morozova, Roman Voitetskii, Karuna M Das, Aidar Kashapov, Nirmin A Mansour, Mai A Fathi, Mohammed Khogali, Milos Ljubisavljevic, Yauhen Statsenko

Background: In blunt chest trauma, patient management is challenging because clinical guidelines miss tools for risk assessment. No clinical scale reliably measures the severity of cases and the chance of complications.

Aim: The objective of the study was to optimize the management of patients with blunt chest trauma by creating models prognosticating the transfer to the intensive care unit and in-hospital length of stay (LOS).

Methods: The study cohort consisted of 212 cases. We retrieved information on the cases from the hospital's trauma registry. After segmenting the lungs with Lung CT Analyzer, we performed volumetric feature extraction with data-characterization algorithms in PyRadiomics.

Results: To predict whether the patient will require intensive care, we used the three groups of findings: ambulance, admission, and radiomics data. When trained on the ambulance data, the models exhibited a borderline performance. The metrics improved after we retrained the models on a combination of ambulance, laboratory, radiologic, and physical examination data (81.5% vs. 94.4% Sn). Radiomics data were the top-accurate predictors (96.3% Sn). Age, vital signs, anthropometrics, and first aid time were the best-performing features collected by the ambulance service. Laboratory findings, AIS scores for the lower extremity, abdomen, head, and thorax constituted the top-rank predictors received on admission to the hospital. The original first-order kurtosis had the highest predictive value among radiomics data. Top-informative radiomics features were derived from the right hemithorax because the right lung is larger. We constructed regression models that can adequately reflect the in-hospital LOS. When trained on different groups of data, the machine-learning regression models showed similar performance (MAE/ROV 8%). Anatomic scores for the body parts other than thorax and laboratory markers of hemorrhage had the highest predictive value. Hence, the number of injured body parts correlated with the case severity.

Conclusion: The study findings can be used to optimize the management of patients with a chest blunt injury as a specific case of monotrauma. The models we built may help physicians to stratify patients by risk of worsening and overcome the limitations of existing tools for risk assessment. High-quality AI models trained on radiomics data demonstrate superior performance.

背景:在钝性胸部创伤中,由于临床指南缺少风险评估工具,因此患者管理具有挑战性。目的:本研究的目的是通过建立转入重症监护室和住院时间(LOS)的预后模型,优化胸部钝挫伤患者的管理:研究队列包括 212 个病例。方法:研究队列由 212 个病例组成,我们从医院的创伤登记处获取了这些病例的信息。用肺部 CT 分析仪分割肺部后,我们用 PyRadiomics 中的数据特征算法进行了容积特征提取:为了预测患者是否需要重症监护,我们使用了三组结果:救护车数据、入院数据和放射组学数据。在救护车数据上训练时,模型表现出了边缘性能。在我们结合救护车、实验室、放射和体检数据对模型进行重新训练后,指标有所改善(81.5% 对 94.4%)。放射组学数据是最准确的预测指标(96.3% Sn)。年龄、生命体征、人体测量和急救时间是救护车服务收集的表现最好的特征。实验室检查结果、下肢、腹部、头部和胸部的 AIS 评分是入院时收到的最佳预测指标。在放射组学数据中,原始一阶峰度的预测价值最高。由于右肺面积较大,因此信息量最大的放射组学特征来自右半胸。我们构建的回归模型可以充分反映院内生命周期。在对不同组数据进行训练时,机器学习回归模型表现出相似的性能(MAE/ROV ≈ 8%)。胸腔以外身体部位的解剖学评分和出血的实验室指标具有最高的预测价值。因此,受伤身体部位的数量与病例的严重程度相关:研究结果可用于优化对胸部钝伤患者的管理,因为胸部钝伤是一种特殊的单发创伤。我们建立的模型可以帮助医生根据病情恶化的风险对患者进行分层,克服现有风险评估工具的局限性。根据放射组学数据训练的高质量人工智能模型表现出卓越的性能。
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引用次数: 0
Sex differences in inflammatory parameters after shoulder arthroplasty and blood loss. 肩关节置换术和失血后炎症指标的性别差异。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1264443
Stefan Hertling, Ekkehard Schleußner, Franziska Maria Loos, Niklas Eckhardt, Mario Kaiser, Isabel Graul

Background: In many diseases, sex differences in diagnostics and therapy play role that is increasingly becoming recognized as important. C-reactive protein (CRP) and white blood cell (WBC) levels are determined as inflammatory markers to detect inflammation and even infection after total shoulder arthroplasty (TSA). The general course of white blood cell, CRP, and hemoglobin (Hb) levels after TSA is well known, but there is insufficient evidence of a possible association with sex. Therefore, we aimed to investigate whether there is an influence of sex on CRP, WBCs, and Hb after TSA in the first 10 days after surgery in a complication-free course in male and female patients and to re-evaluate the specific postoperative CRP, WBC, and Hb course with their maximums (minimum for Hb) and further course until the end of the inpatient period.

Methods: We retrospectively studied patients treated with TSA, reverse shoulder arthroplasty (RSA), and prosthesis replacement between 2015 and 2021. Patients with active inflammation, rheumatoid arthritis, secondary osteoarthritis, active cancer, and documented postoperative complications were not included. CRP, WBC, and Hb levels before shoulder arthroplasty (SA) and up to 10 days after SA were recorded and analyzed for sex differences.

Results: Data from a total of 316 patients (209 women and 107 men) were finally analyzed. There were no sex differences in the CRP and WBC values, but women had significantly lower preoperative Hb values, postoperative Hb values, and minimum Hb values. There were no significant differences in Hb, CRP, or WBC levels in the prosthesis exchange group.

Conclusion: The progression of CRP and WBC levels showed no sex-specific significant differences after TSA within the first 7 postoperative days. The study confirmed a decreased Hb value for women at all stages of SA. Blood loss was significantly higher for RSA than for TSA for both men and women.

背景:在许多疾病的诊断和治疗中,性别差异所起的作用越来越重要。C反应蛋白(CRP)和白细胞(WBC)水平是检测全肩关节置换术(TSA)后炎症甚至感染的炎症标志物。众所周知,TSA术后白细胞、CRP和血红蛋白(Hb)水平的一般变化过程,但没有足够的证据表明这可能与性别有关。因此,我们旨在研究在无并发症的情况下,男性和女性患者在 TSA 术后前 10 天内的 CRP、WBC 和 Hb 是否受性别影响,并重新评估术后 CRP、WBC 和 Hb 的具体变化过程及其最大值(Hb 最小值)和直至住院期结束的进一步变化过程:我们对2015年至2021年间接受TSA、反向肩关节置换术(RSA)和假体置换术治疗的患者进行了回顾性研究。不包括活动性炎症、类风湿性关节炎、继发性骨关节炎、活动性癌症和有记录的术后并发症患者。记录肩关节置换术(SA)前和术后10天内的CRP、白细胞和血红蛋白水平,并分析性别差异:结果:最终分析了316名患者(209名女性和107名男性)的数据。CRP 和白细胞值没有性别差异,但女性的术前 Hb 值、术后 Hb 值和最低 Hb 值明显较低。假体置换组的 Hb、CRP 和 WBC 水平无明显差异:结论:TSA术后头7天内,CRP和白细胞水平的变化无明显性别差异。研究证实,女性在 SA 的各个阶段 Hb 值均有所下降。无论男性还是女性,RSA 的失血量都明显高于 TSA。
{"title":"Sex differences in inflammatory parameters after shoulder arthroplasty and blood loss.","authors":"Stefan Hertling, Ekkehard Schleußner, Franziska Maria Loos, Niklas Eckhardt, Mario Kaiser, Isabel Graul","doi":"10.3389/fsurg.2024.1264443","DOIUrl":"https://doi.org/10.3389/fsurg.2024.1264443","url":null,"abstract":"<p><strong>Background: </strong>In many diseases, sex differences in diagnostics and therapy play role that is increasingly becoming recognized as important. C-reactive protein (CRP) and white blood cell (WBC) levels are determined as inflammatory markers to detect inflammation and even infection after total shoulder arthroplasty (TSA). The general course of white blood cell, CRP, and hemoglobin (Hb) levels after TSA is well known, but there is insufficient evidence of a possible association with sex. Therefore, we aimed to investigate whether there is an influence of sex on CRP, WBCs, and Hb after TSA in the first 10 days after surgery in a complication-free course in male and female patients and to re-evaluate the specific postoperative CRP, WBC, and Hb course with their maximums (minimum for Hb) and further course until the end of the inpatient period.</p><p><strong>Methods: </strong>We retrospectively studied patients treated with TSA, reverse shoulder arthroplasty (RSA), and prosthesis replacement between 2015 and 2021. Patients with active inflammation, rheumatoid arthritis, secondary osteoarthritis, active cancer, and documented postoperative complications were not included. CRP, WBC, and Hb levels before shoulder arthroplasty (SA) and up to 10 days after SA were recorded and analyzed for sex differences.</p><p><strong>Results: </strong>Data from a total of 316 patients (209 women and 107 men) were finally analyzed. There were no sex differences in the CRP and WBC values, but women had significantly lower preoperative Hb values, postoperative Hb values, and minimum Hb values. There were no significant differences in Hb, CRP, or WBC levels in the prosthesis exchange group.</p><p><strong>Conclusion: </strong>The progression of CRP and WBC levels showed no sex-specific significant differences after TSA within the first 7 postoperative days. The study confirmed a decreased Hb value for women at all stages of SA. Blood loss was significantly higher for RSA than for TSA for both men and women.</p>","PeriodicalId":12564,"journal":{"name":"Frontiers in Surgery","volume":"11 ","pages":"1264443"},"PeriodicalIF":1.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
C-arm CT scanning combined with simple laser device-assisted puncture therapy for cerebellar hemorrhage. C 型臂 CT 扫描结合简单激光设备辅助穿刺疗法治疗小脑出血。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1421517
Yang Chen, Chenglong Li, Qingbo Wang, Zefu Li

Background: Cerebellar hemorrhage is a severe cerebrovascular disease. The small posterior fossa space can cause compression of surrounding brain tissue with even a small amount of bleeding, leading to increased intracranial pressure, disruption of blood supply to surrounding brain tissue, and exacerbation of brain function damage. The most common surgical approach currently is craniotomy for hematoma evacuation, inevitably causing damage to surrounding nerves and blood vessels. In this study, we introduced C-arm CT scanning combined with simple laser device technology to assist in puncture drainage for cerebellar hemorrhage, aiming to improve the accuracy of surgery and maximize the protection of patients' brain function, providing a physiological basis for better clinical prognosis.

Materials and methods: From January 2023 to February 2024, a total of 8 patients (6 males, 2 females) with cerebellar hemorrhage underwent C-arm CT-assisted puncture therapy combined with a simple laser device at the affiliated hospital of Binzhou Medical University. Statistical analysis was performed on operation time, number of punctures, impact on important structures and vessels, postoperative hematoma clearance, complications, and neurological function recovery.

Results: All 8 patients underwent the surgery smoothly without causing damage to important structures or blood vessels. There was no rebleeding intraoperatively. Among the 8 patients, 5 were discharged smoothly, while 3 patients opted to discontinue treatment and requested discharge. At the 3-month follow-up, 3 patients showed no ataxia, while 2 patients had impaired cerebellar motor function.

Conclusion: C-arm CT scanning combined with a simple laser device technology can accurately locate the position of the hematoma, effectively avoid important structures and vessels, reduce damage to surrounding normal brain tissue, and maximize the protection of normal brain tissue function. Real-time navigation and dynamic adjustments during surgery allow immediate access to imaging data postoperatively. It also has the advantages of being minimally invasive, highly precise, easy to operate, and short operation time, demonstrating high practicality and feasibility.

背景:小脑出血是一种严重的脑血管疾病:小脑出血是一种严重的脑血管疾病。小脑后窝空间狭小,即使少量出血也会压迫周围脑组织,导致颅内压增高,周围脑组织供血中断,加重脑功能损伤。目前最常见的手术方法是开颅血肿清除术,不可避免地会对周围神经和血管造成损伤。本研究引入C臂CT扫描结合简易激光设备技术辅助小脑出血穿刺引流,旨在提高手术的准确性,最大限度保护患者脑功能,为临床更好的预后提供生理依据:自2023年1月至2024年2月,滨州医科大学附属医院共对8例(男6例,女2例)小脑出血患者进行了C臂CT辅助穿刺联合简易激光装置治疗。对手术时间、穿刺次数、对重要结构和血管的影响、术后血肿清除情况、并发症、神经功能恢复情况进行了统计分析:8例患者均顺利完成手术,未对重要结构和血管造成损伤。术中无再出血。8 名患者中,5 人顺利出院,3 人选择中止治疗并要求出院。在3个月的随访中,3名患者未出现共济失调,2名患者的小脑运动功能受损:结论:C臂CT扫描结合简单的激光设备技术,可以准确定位血肿位置,有效避开重要结构和血管,减少对周围正常脑组织的损伤,最大限度地保护正常脑组织功能。术中实时导航、动态调整,术后可立即获取成像数据。它还具有微创、精确度高、操作简便、手术时间短等优点,具有很高的实用性和可行性。
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引用次数: 0
Robotic colorectal surgery in Latin America: a systematic review on surgical outcomes. 拉丁美洲的机器人结直肠手术:手术效果系统回顾。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1480444
Bruno Augusto Alves Martins, Nicolas Avellaneda, Guglielmo Niccolò Piozzi

Background and objectives: Robotic approach in colorectal surgery is rapidly gaining interest, particularly in the context of rectal cancer resection. Despite economic barriers, substantial proliferation of robotic colorectal procedures has been observed throughout Latin America. However, there is a lack of data regarding intraoperative and early postoperative outcomes, as well as oncological and long-term results. This systematic review aims to provide an overview of the surgical outcomes of robotic-assisted colorectal approaches across Latin America.

Material and methods: A systematic literature search of electronic databases, including PubMed, LILACS, Scopus, Cochrane Library and Scielo, was performed and reported in line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The main target of the literature search was studies that reported outcomes of colorectal robotic surgery in Latin America.

Results: A total of 9,694 published articles were identified from the initial search. Nine thousand six hundred thirty-six publications were excluded after title and abstract review and removal of duplicates. Fifty-eight articles were thoroughly reviewed, and 11 studies met the inclusion criteria. The critical appraisal of study quality (biases risk assessment) was performed according to the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis. In general, the overall study quality was poor. Of the 11 studies included in the analysis, ten addressed intraoperative and early postoperative outcomes, seven addressed oncological/pathological outcomes, and just one addressed long-term outcomes. Ten studies evaluated intraoperative and early postoperative outcomes, encompassing a total of 425 patients, the majority of whom were diagnosed with colorectal cancer. Morbidity rates exhibited a range between 0% and 45.9%, while mortality ranged from 0% to 2.5%.

Conclusion: Few studies have been published addressing intraoperative, postoperative, pathological, and oncological outcomes of robotic colorectal surgery in this region. Undoubtedly, there are unique challenges not encountered by developed countries, including economic obstacles in establishing structured training programmes and high-quality centres for the development of robotic surgery. Further studies are needed to assess the real extent of robotic surgery in the region and its results.

Systematic review registration: https://www.crd.york.ac.uk/, PROSPERO (CRD42023494112).

背景和目的:机器人结直肠手术方法正迅速受到关注,尤其是在直肠癌切除方面。尽管存在经济障碍,但在整个拉丁美洲,机器人结直肠手术已大量普及。然而,有关术中、术后早期疗效以及肿瘤学和长期疗效的数据还很缺乏。本系统性综述旨在概述拉丁美洲机器人辅助结直肠手术的手术效果:对电子数据库(包括 PubMed、LILACS、Scopus、Cochrane Library 和 Scielo)进行了系统的文献检索,并根据《系统综述和元分析首选报告项目》指南进行了报告。文献检索的主要目标是报告拉丁美洲结直肠机器人手术结果的研究:初步检索共发现 9,694 篇已发表文章。在对标题和摘要进行审查并去除重复内容后,排除了 9,636 篇出版物。对 58 篇文章进行了全面审查,其中 11 项研究符合纳入标准。根据乔安娜-布里格斯研究所(JBI)的《证据综合手册》对研究质量进行了严格评估(偏倚风险评估)。总体而言,研究的整体质量较差。在纳入分析的 11 项研究中,有 10 项涉及术中和术后早期疗效,7 项涉及肿瘤/病理疗效,仅有 1 项涉及长期疗效。十项研究对术中和术后早期疗效进行了评估,共涉及 425 名患者,其中大部分被确诊为结直肠癌。发病率在 0% 到 45.9% 之间,死亡率在 0% 到 2.5% 之间:结论:针对该地区机器人结直肠手术的术中、术后、病理和肿瘤结果的研究很少。毫无疑问,该地区面临着发达国家所没有的独特挑战,包括在建立结构化培训计划和高质量的机器人手术发展中心方面的经济障碍。要评估机器人手术在该地区的实际应用范围及其效果,还需要进一步的研究。系统综述注册:https://www.crd.york.ac.uk/,PROSPERO (CRD42023494112)。
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引用次数: 0
Integrating 3D technology with the Sampaio classification for enhanced percutaneous nephrolithotomy in complex renal calculi treatment. 将三维技术与桑帕约分类法相结合,加强经皮肾镜碎石术在复杂肾结石治疗中的应用。
IF 1.6 4区 医学 Q2 SURGERY Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fsurg.2024.1471958
Jiamo Zhang, Jing Qing, Ke Hu, Honglin Cheng

Background: To investigate the safety and efficacy of percutaneous nephrolithotomy (PCNL) in the treatment of complicated renal calculi by integrating three-dimensional (3D) computed tomography (CT) reconstruction with the Sampaio classification of the renal collecting system.

Methods: Sixty-four consecutive patients with complex kidney calculi who underwent PCNL between January 2019 and October 2023 were retrospectively analyzed and divided into experimental group (3D printing) and control group (CT imaging) according to their willingness to pay for 3D imaging. Both groups underwent preoperative CT urography. The Digital Imaging and Communications (DICOM) in Medicine data of the experimental group from CT imaging were used for 3D reconstruction and model printing. Then, the Sampaio classification system was used to design the puncture channel and develop a surgical strategy.

Results: The 3D-printed models of the experimental group successfully displayed the Sampaio classification system. There was no significant difference in the baseline parameters between the groups. Compared with the control group, the experimental group exhibited significant improvements in the puncture time, number of puncture needles, number of puncture channels, target calyx consistency, number of first puncture channels, and stone clearance. There were no significant differences in the total operative time, decrease in the hemoglobin level, length of hospital stay, and postoperative complications between the groups.

Conclusions: Integration of 3D technology with the Sampaio classification of the renal collecting system can enhance the preoperative evaluation and planning of percutaneous renal access. This approach allows a more precise method of PCNL for treating complex renal calculi.

背景:目的:通过将三维(3D)计算机断层扫描(CT)重建与Sampaio肾集合系统分类相结合,研究经皮肾镜取石术(PCNL)治疗复杂肾结石的安全性和有效性:对2019年1月至2023年10月期间接受PCNL的64例连续复杂肾结石患者进行回顾性分析,并根据患者对3D成像的付费意愿分为实验组(3D打印)和对照组(CT成像)。两组均进行术前 CT 尿路造影。实验组的 CT 成像中的数字成像和通信(DICOM)医学数据被用于三维重建和模型打印。然后,利用桑帕约分类系统设计穿刺通道并制定手术策略:结果:实验组的三维打印模型成功显示了桑帕约分类系统。两组的基线参数无明显差异。与对照组相比,实验组在穿刺时间、穿刺针数、穿刺通道数、靶萼稠度、首次穿刺通道数和结石清除率方面均有显著改善。两组在手术总时间、血红蛋白水平下降、住院时间和术后并发症方面无明显差异:结论:将三维技术与桑帕约肾集合系统分类相结合,可提高经皮肾通路的术前评估和规划。结论:将三维技术与桑帕约肾集合系统分类相结合,可加强术前评估和经皮肾通路规划,从而采用更精确的 PCNL 方法治疗复杂的肾结石。
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引用次数: 0
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Frontiers in Surgery
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