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Antibacterial Potential of Sarang Semut Herbal Extract (Myrmecodia pendans) from Timor Against Staphylococcus aureus: An In Vitro Study 帝汶的 Sarang Semut 草本提取物(Myrmecodia pendans)对金黄色葡萄球菌的抗菌潜力:体外研究
Pub Date : 2024-02-02 DOI: 10.5539/gjhs.v16n2p57
Abdul Majid, Frans Salesman, Emanuel Gerald Alan Rahmat, Nikmah Nikmah
BACKGROUND: The resistance of Staphylococcus aureus bacteria to antibiotics is still a problem in clinical medicine. The potential of Ant-nest plant extract (Myrmecodia pendans) from the island of Timor as an antibacterial needs to be tested to be used as a new alternative. OBJECTIVE: This study aims to determine the antibacterial potential and dose level of Myrmecodia pendans extract from Timor as bacteriostatic and bactericidal bacteria against Staphylococcus aureus in vitro. METHOD: This study is an experimental study, using five doses of Myrmecodia pendans extract from Timor, namely positive control (cephalexin drug) and negative control (200 μl ethanol 95% + 50 μl DMSO), concentration 62.5 mg/ml (P1), concentration 125 mg/ml (P2), concentration 250 mg/ml (P3), concentration 500 mg/ml (P4), and concentration 1000 mg/ml (P5), with five replications each. Samples of Myrmecodia pendans, taken from Nonbaun Village, Central Fatuleu District, Kupang Regency, Mauleum Village, East Amanuban District, and Oenae Village, Kie District, South Central Timor Regency. The Kupang City Food and Drug Control Center obtained the test bacteria. Data were obtained and analyzed using the Standard Plate Count (SPC) method. The SPC value of each treatment was compared with the SPC value of the control treatment. RESULTS: The results of the analysis showed that the positive control treatment (0), negative control, and concentration treatment of 62.5 mg/ml (P1) had too much bacterial growth value (TBUD). Conversely, treatment with concentrations of 125 mg/ml (P2) and 250 mg/ml (P3) has a Minimum Inhibition Concentration (MIC) value of 9.4 x 104 CFU / ml and 6.7 x 104 CFU / ml, respectively. Treatment with concentrations of 500 mg/ml (P4) and 1000 mg/ml (P5) can both kill bacteria with a Minimum Bactericidal Concentration (MBC) value of 0. CONCLUSION: Myrmecodia pendans extract from Timor Island has bacteriostatic potential (inhibits) the growth of Staphylococcus aureus bacteria at a concentration of at least 125 mg/ml and potentially bactericidal (deadly) at a concentration of at least 500 mg/ml.
背景:金黄色葡萄球菌对抗生素的耐药性仍然是临床医学中的一个问题。需要测试帝汶岛蚁巢植物提取物(Myrmecodia pendans)作为抗菌剂的潜力,以便将其用作新的替代品。 目的:本研究旨在确定帝汶岛蚁巢植物提取物(Myrmecodia pendans)对金黄色葡萄球菌的体外抑菌和杀菌潜力及剂量水平。 方法:本研究是一项实验研究,使用五种剂量的帝汶Myrmecodia pendans提取物,即阳性对照(头孢氨苄药物)和阴性对照(200 μl 95%乙醇 + 50 μl DMSO)、浓度为62.5 mg/ml (P1)、浓度为125 mg/ml (P2)、浓度为250 mg/ml (P3)、浓度为500 mg/ml (P4)和浓度为1000 mg/ml (P5),每个剂量有五个重复。Myrmecodia pendans 样本取自古邦摄政区 Fatuleu 中区 Nonbaun 村、Amanuban 东区 Mauleum 村和帝汶摄政区中南部 Kie 区 Oenae 村。古邦市食品药品控制中心获得了测试细菌。数据采用标准平板计数法(SPC)获得和分析。将各处理的 SPC 值与对照处理的 SPC 值进行比较。 结果:分析结果显示,阳性对照处理(0)、阴性对照和浓度为 62.5 毫克/毫升的处理(P1)的细菌生长值(TBUD)过高。相反,浓度为 125 毫克/毫升(P2)和 250 毫克/毫升(P3)的处理的最小抑菌浓度(MIC)值分别为 9.4 x 104 CFU / ml 和 6.7 x 104 CFU / ml。用浓度为 500 毫克/毫升(P4)和 1000 毫克/毫升(P5)的萃取物处理细菌,其最低杀菌浓度(MBC)值均为 0。 结论:帝汶岛糠虾提取物在浓度至少为 125 毫克/毫升时具有抑菌潜力(抑制)金黄色葡萄球菌的生长,在浓度至少为 500 毫克/毫升时具有潜在的杀菌潜力(致命)。
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引用次数: 0
Reviewer Acknowledgements for Global Journal of Health Science, Vol. 16, No. 2, 2024. 全球健康科学杂志》(Global Journal of Health Science)第 16 卷第 2 期(2024 年)审稿人致谢。
Pub Date : 2024-02-02 DOI: 10.5539/gjhs.v16n2p64
E. Grey
Reviewer Acknowledgements for Global Journal of Health Science, Vol. 16, No. 2.
全球健康科学杂志》第 16 卷第 2 期审稿人致谢。
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引用次数: 0
Creatine Supplements: What the Research Says about How It Can Help Healthy Athletes 肌酸补充剂:关于肌酸如何帮助健康运动员的研究报告
Pub Date : 2024-01-23 DOI: 10.5539/gjhs.v16n2p48
Mimansa Dahal, K. Dahal, Nawa Raj Pokhrel, Durga Kutal
Creatine is a popular and widely used ergogenic dietary supplement among athletes, for which studies have consistently shown increased lean muscle mass and exercise capacity when used with short-duration, high-intensity exercise. This article provides an overview of creatine supplementation, particularly in the context of athletes, focusing on its safety, benefits, dosage, and considerations for young individuals. Research has shown that creatine supplementation may provide additional benefits including enhanced post-exercise recovery, injury prevention, and rehabilitation, as well as several potential neurological benefits that may be relevant to sports. Studies show that short- and long-term supplementation is safe and well-tolerated in healthy individuals and several patient populations.
肌酸是一种在运动员中广为流行和广泛使用的生肌膳食补充剂,研究一致表明,在短时间、高强度运动中使用肌酸可增加瘦肌肉质量和运动能力。本文概述了肌酸补充剂,特别是针对运动员的肌酸补充剂,重点介绍了肌酸补充剂的安全性、益处、剂量以及对年轻人的注意事项。研究表明,补充肌酸可带来更多益处,包括增强运动后恢复、预防损伤和康复,以及可能与运动相关的几种潜在神经益处。研究表明,短期和长期补充肌酸对健康人和一些病人群体都是安全和耐受性良好的。
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引用次数: 0
Socio-Demographic Determinants of Quality of Life Among Aging Population in Thailand 泰国老龄化人口生活质量的社会人口决定因素
Pub Date : 2023-11-13 DOI: 10.5539/gjhs.v15n12p37
Yodfah Ratmanee, Phattrawan Tongkumchum
Thailand is becoming an aged society. It is very important to investigate the effect of Thailand becoming an aged society. It is crucial to examine the impact of socio-demographic factors on quality of life (QoL) for population aging. This study aimed to understand the QoL of older adults aged 60 years or older based on their socio-demographic status. Using the data of 13 Regional Health (RH) of Thailand from 2012-2018. QoL was measured with the Thai version of the WHOQOL-BREF. A total of 400 older adults were selected from each region each year. To analyze the factors affecting the QoL between 2012 and 2018, the linear regression model was used. The results showed that the QoL significantly increases with age for both sexes. The QoL was significantly higher than the overall mean in the married and secured income groups. According to time, the QoL in 2015 was significantly lower than the overall mean. In addition, the groups of adults in Bangkok, lower northeast, southwest, and south of the country showed a significantly lower QoL.
泰国正在成为一个老龄化社会。研究泰国成为老龄化社会的影响是非常重要的。研究社会人口因素对人口老龄化生活质量(QoL)的影响至关重要。本研究旨在了解60岁及以上老年人在社会人口统计学上的生活质量状况。使用2012-2018年泰国13个区域卫生(RH)的数据。生活质量采用泰国版WHOQOL-BREF进行测量。每年从每个地区共选出400名老年人。为了分析2012 - 2018年影响生活质量的因素,采用线性回归模型。结果表明,随着年龄的增长,男女的生活质量都显著增加。已婚及有稳定收入人士的生活质素明显高于整体平均水平。从时间上看,2015年的生活质量明显低于整体平均水平。此外,曼谷、东北、西南和南部的成虫群体的生活质量明显较低。
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引用次数: 0
Incidence of Recurrent Low Back Pain as a Side Effect of Decompressive Surgery for Lumbar Spinal Stenosis in Obese Versus Non-Obese Patients 肥胖与非肥胖患者腰椎管狭窄减压手术副作用中复发性腰痛的发生率
Pub Date : 2023-10-30 DOI: 10.5539/gjhs.v15n12p29
Abdullah Ali Alzahrani, Mohammad Abdullah Alhasani
Studies have reported an increased incidence of recurrent post-decompression-associated lower back pain (LBP) among obese patients after Lumbar spinal stenosis (LSS) surgery. Higher prevalence of lower back pain (LBP) associated with post-decompression surgical treatment among obese or overweight female patients compared to male patients. The current study has aimed to examine the relationship between body composition and long-duration consequences of post-spinal decompression among the Saudi population. This retrospective, longitudinal study was conducted at Taif Hospital, Kingdom of Saudi Arabia (KSA), throughout ____2010-till 2015 ____. Chronic pain grade questionnaire for assessing lower back pain and any disability among post-decompression participants. The chi-square test was used to analyze independent variables, and an independent t-test was employed to detect variances between mobility, age, education, body composition, and emotional disorders. The adjustment of age, education, mobility, emotional disorder, and BMI was examined through multivariate analysis. Highly a statistically substantial difference between obese and non-obese with regard to age, emotional distress, low mobility, Body mass index (BMI), mean estimated flow of blood (p-value <0.000), and hospitalization (p-value <0.002). The results showed a statistically substantial relationship between the degree of pain and disability with patient weight (p-value: 0.05), body mass index (p-value: 0.03), and Fat mass/fat-free mass ratio (p-value: 0.05). Clinical improvement is observed in obese patients post decompression surgical intervention, but the percentage of improvement was significantly higher among the male gender compared to female obese patients.
研究报道肥胖患者腰椎管狭窄症(LSS)手术后复发性减压相关腰痛(LBP)的发生率增加。与男性患者相比,肥胖或超重女性患者与减压手术后相关的腰痛(LBP)患病率更高。目前的研究旨在检查沙特人口中身体成分与脊柱减压后长期后果之间的关系。这项回顾性纵向研究于____2010- 2015年期间在沙特阿拉伯王国(KSA)塔伊夫医院进行____。用于评估减压后参与者腰痛和任何残疾的慢性疼痛等级问卷。采用卡方检验分析自变量,采用独立t检验检测活动能力、年龄、文化程度、身体成分、情绪障碍之间的差异。通过多变量分析对年龄、受教育程度、活动能力、情绪障碍和BMI进行调整。肥胖和非肥胖在年龄、情绪困扰、低活动能力、身体质量指数(BMI)、平均估计血流量(p值<0.000)和住院率(p值<0.002)方面具有高度统计学上的显著差异。结果显示,疼痛程度和残疾程度与患者体重(p值:0.05)、体重指数(p值:0.03)和脂肪质量/无脂肪质量比(p值:0.05)之间存在显著的统计学关系。肥胖患者在减压手术干预后临床改善,但男性肥胖者的改善百分比明显高于女性肥胖者。
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引用次数: 0
Clinical Evaluation and Diagnosis of Prevalent Thyroid Disorders in Primary Care: A Comprehensive Case Series 临床评价和诊断流行甲状腺疾病在初级保健:一个全面的病例系列
Pub Date : 2023-10-16 DOI: 10.5539/gjhs.v15n11p44
Basem Abbas Ahmed Al Ubaidi
Thyroid diseases are prevalent in primary care settings, encompassing a wide spectrum of disorders such as hypothyroidism, hyperthyroidism, and thyroid nodules. Early and accurate diagnosis is crucial for effective management and improved patient outcomes. This case series provides an overview of the key diagnostic approaches for common thyroid diseases in primary care. The diagnosis of common thyroid diseases in primary care relies on a combination of clinical assessment, laboratory tests, imaging studies, and, if necessary, biopsy. Early and accurate diagnosis is essential for guiding appropriate treatment strategies and optimizing patient well-being. Primary care physicians play a vital role in identifying and managing thyroid disorders, ensuring that patients receive timely and effective care.
甲状腺疾病在初级保健机构中很普遍,包括各种疾病,如甲状腺功能减退、甲状腺功能亢进和甲状腺结节。早期和准确的诊断对于有效管理和改善患者预后至关重要。本病例系列概述了初级保健中常见甲状腺疾病的主要诊断方法。 & # x0D;初级保健中常见甲状腺疾病的诊断依赖于临床评估、实验室检查、影像学检查以及必要时活检的结合。早期和准确的诊断对于指导适当的治疗策略和优化患者福祉至关重要。初级保健医生在识别和管理甲状腺疾病方面发挥着至关重要的作用,确保患者得到及时有效的护理。
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引用次数: 0
Mapping Evidence on the Determinants of Postnatal Care Knowledge among Postpartum Women in sub-Saharan Africa: A Literature Review 撒哈拉以南非洲产后妇女产后护理知识决定因素的制图证据:文献综述
Pub Date : 2023-10-13 DOI: 10.5539/gjhs.v15n12p16
Enos Moyo, Perseverance Moyo, Tafadzwa Dzinamarira, Grant Murewanhema, Andrew Ross
Maternal and neonatal deaths continue to pose significant public health challenges globally. In 2020, low-to-middle-income countries accounted for over 95% of all maternal deaths. Sub-Saharan Africa (SSA) is the region most severely impacted, accounting for 70% of global maternal deaths in 2020. Most of the maternal deaths and about a third of child deaths occur in the postnatal period. These unnecessary deaths can be avoided if postpartum women have adequate knowledge about postnatal care (PNC). This literature review&rsquo;s aim was to determine the factors that influence PNC knowledge among postpartum women in SSA. The methodology of this literature review was loosely guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) statement. Peer-reviewed articles describing determinants of PNC knowledge among postpartum women in SSA published in English between 2013 and 2023 were searched using several search engines. All the twenty-five articles used in this literature review reported on quantitative cross-sectional studies. Some of the individual-level determinants of PNC knowledge identified in this review include place of residence, age of the mother, marital status, educational status of the mother, and the socio-economic status of the woman while the health system-level determinants include distance to a healthcare facility, source of PNC information, place of delivery, and previous maternal healthcare service experience. To improve PNC knowledge of postpartum women, we recommend developing rural areas through improving transport networks, improving the socio-economic status of women, and devising strategies to increase maternal and child health services utilization.
孕产妇和新生儿死亡继续对全球公共卫生构成重大挑战。2020年,低收入和中等收入国家占孕产妇死亡总数的95%以上。撒哈拉以南非洲是受影响最严重的区域,占2020年全球孕产妇死亡人数的70%。大多数产妇死亡和大约三分之一的儿童死亡发生在产后。如果产后妇女对产后护理有足够的了解,这些不必要的死亡是可以避免的。本文献综述的目的是确定影响SSA产后妇女PNC知识的因素。本文献综述的方略遵循系统评价和荟萃分析方案优选报告项目(PRISMA-P)声明。使用多个搜索引擎检索2013年至2023年间发表的英文同行评议文章,这些文章描述了SSA产后妇女PNC知识的决定因素。本文献综述中使用的所有25篇文章均报道了定量横断面研究。本综述中确定的一些个人层面的PNC知识决定因素包括居住地、母亲的年龄、婚姻状况、母亲的教育状况和妇女的社会经济地位,而卫生系统层面的决定因素包括到医疗机构的距离、PNC信息来源、分娩地点和以前的孕产妇保健服务经验。为了提高产后妇女的PNC知识,我们建议通过改善交通网络、提高妇女的社会经济地位和制定战略来发展农村地区,以提高孕产妇和儿童保健服务的利用率。
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引用次数: 0
The Primary Health Care Approach: Rhetoric or Policy? - A Review of National Health Policies in 8 Countries in Southern Africa 初级卫生保健方法:修辞还是政策?-审查南部非洲8个国家的国家卫生政策
Pub Date : 2023-10-12 DOI: 10.5539/gjhs.v15n12p1
Gamuchirai P. Gwaza, Marcy McCall MacBain, Annette Annette Plüddemann, Carl Heneghan
INTRODUCTION: The Primary Health Care approach (PHC) can contribute towards universal health coverage (UHC). However, implementing the PHC approach in Africa remains suboptimal. One way to ascertain political commitment to the PHC approach is its reflection in the national health policies (NHP). Several PHC initiatives have helped define and guide the PHC definition, implementation, and evaluation. These include the Alma Ata PHC conference, the Ouagadougou Declaration on PHC in Africa, and the Astana conference. The aim of this paper is to explore to what extent the guidance and characteristics of the PHC approach have been reflected and integrated into the National Health Policies (NHPs) in countries in the Southern African Development Community (SADC). METHODS: The READ approach was undertaken to analyze eight publicly available NHPs. A 12-point checklist was developed to extract relevant data from the policy documents.&nbsp; The WHO Health Systems building blocks are used as the analytical framework to understand the key features of the PHC approach mentioned in the policies. RESULTS: All the NHPs were developed after the Alma Ata conference in 1978. Six of the eight NHPs reviewed were updated after the Ouagadougou declaration on PHC in Africa in 2008. None of the NHPs were updated after the 2018 Astana PHC conference. Based on the checklist, Lesotho had the most integrated PHC elements (n=12), while Eswatini had the least (n=4). Based on the policy review, there seems to be commitment and priority placed on leadership, governance, and access to essential medicines. However, more still needs to be done to improve service delivery in terms of integrated patient centered care (only included in 3 out of the 8), health financing for primary care, integrated health information systems and the community health workers as part of the health workforce. CONCLUSION: In conclusion, NHPs should guide implementation, and the NHP is a reference document for many organizations wishing to partner with the government in improving health care services. As such, it should be updated in line with the new evidence and learning and reflect the country&rsquo;s priorities to help align development actors.
初级卫生保健方法(PHC)可以促进全民健康覆盖(UHC)。然而,在非洲实施初级保健方法仍然不够理想。确定对初级保健方法的政治承诺的一种方法是将其反映在国家卫生政策中。几个PHC计划帮助定义和指导PHC的定义、实现和评估。这些会议包括阿拉木图初级卫生保健会议、关于非洲初级卫生保健的瓦加杜古宣言和阿斯塔纳会议。本文的目的是探讨在南部非洲发展共同体(SADC)国家的国家卫生政策(NHPs)中,初级保健方法的指导和特点在多大程度上得到了反映和整合。& # x0D;& # x0D;方法:采用READ方法分析8个公开可用的NHPs。制定了一份12点清单,从政策文件中提取相关数据。世卫组织卫生系统构建模块被用作分析框架,以了解政策中提到的初级保健方法的主要特征。& # x0D;结果:所有NHPs都是在1978年阿拉木图会议之后制定的。在审查的8个国家卫生规划中,有6个在2008年《瓦加杜古非洲初级卫生保健宣言》之后得到更新。在2018年阿斯塔纳初级卫生保健会议之后,所有国家卫生规划都没有更新。根据检查表,莱索托的初级保健要素整合度最高(n=12),而斯威士兰的初级保健要素整合度最低(n=4)。根据政策审查,似乎在领导、治理和获得基本药物方面作出了承诺并给予了优先考虑。然而,在以患者为中心的综合护理(仅包括8项中的3项)、初级保健卫生筹资、综合卫生信息系统和作为卫生人力的一部分的社区卫生工作者方面,仍需要做更多的工作来改善服务提供。& # x0D;& # x0D;结论:总而言之,国家卫生计划应指导实施,国家卫生计划是许多希望与政府合作改善卫生保健服务的组织的参考文件。因此,它应该根据新的证据和经验进行更新,并反映国家的优先事项,以帮助协调发展行为体。
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引用次数: 0
The Effect of Individual Preferences on Precautionary Behaviors in Vaccine Taking, Saving, and Physical Activity 个体偏好对疫苗接种、保存和身体活动预防行为的影响
Pub Date : 2023-10-04 DOI: 10.5539/gjhs.v15n11p22
Di Wang, Teng-peng Chen, Zhong-hua Shi
The COVID-19 pandemic has underscored the importance of how people react behaviorally to external threats. Precautionary behavioral responses to COVID-19 become apparent. In addition, individual risk and time preferences are related to economic behaviors under uncertainty and health-related behaviors. This study aims to determine whether and how time and risk choices influence precautionary behaviors in vaccine-taking, saving, and physical activity during the coronavirus lockdown. We conducted a cross-sectional study utilizing an online survey, which included a sample of 1016 individuals aged 18 to 60 residing and working in Shanghai. We use logistic regressions to estimate. We have three findings. First, risk-taking and future-oriented individuals are more likely to get vaccinated. Second, future-oriented ones are more inclined to exercise at home via digital media during the lockdown. Third, neither risk preference nor time preference is predictive of precautionary saving. This work aids the literature by documenting time and risk preferences influencing health-related behaviors and life well-being during the lockdown. The conclusions have practical implications from a policy perspective.
2019冠状病毒病大流行凸显了人们如何应对外部威胁的重要性。对COVID-19的预防性行为反应变得明显。此外,个体风险偏好和时间偏好与不确定性下的经济行为和健康相关行为有关。本研究旨在确定在冠状病毒封锁期间,时间和风险选择是否以及如何影响疫苗接种、储蓄和身体活动的预防行为。我们利用在线调查进行了一项横断面研究,其中包括1016名年龄在18至60岁之间居住和工作在上海的个人样本。我们使用逻辑回归来估计。我们有三个发现。首先,冒险和面向未来的个人更有可能接种疫苗。二是面向未来的人群更倾向于在封城期间通过数字媒体在家锻炼。第三,风险偏好和时间偏好都不能预测预防性储蓄。这项工作通过记录封锁期间影响健康相关行为和生活幸福感的时间和风险偏好来帮助文献。从政策角度看,这些结论具有实际意义。
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引用次数: 0
Perceived Risk of Breast Cancer in Relation to Precautionary Behavior among Females in Saudi Arabia 沙特阿拉伯女性乳腺癌风险与预防行为的关系
Pub Date : 2023-10-04 DOI: 10.5539/gjhs.v15n11p14
Nawal A. Alissa
Background: For the last two decades, the number of women with breast cancer in Saudi Arabia increased steadily. Risk perceptions or an individual&#39;s perceived susceptibility to a threat are a key component of many health behavior change theories. Little is known about relationships between risk perceptions of breast cancer and performing preventive practices. This descriptive study highlights the risk perception of breast cancer in relation to preventive interventions among females over 18 years old in Riyadh, Saudi Arabia. Methods: Cross-sectional descriptive correlational design. An online questionnaire was conducted with 500 participants aged 18 years and older. The questionnaire was self-administrated electronic questionnaire designed by using Google Forms and it gated broadcast through social media channels such as WhatsApp and twitter. Results: The study emphasized a low risk perceptions about breast cancer and performing preventive practices. Positive correlation was found between female&#39;s risk perceptions and doing the mammogram screening. Conclusions: Findings will be helpful to use risk perception of breast cancer in the prediction of women adopting preventive measures.
背景:在过去的二十年中,沙特阿拉伯患乳腺癌的妇女人数稳步增加。风险感知或个人对威胁的感知易感性是许多健康行为改变理论的关键组成部分。人们对乳腺癌风险认知与实施预防措施之间的关系知之甚少。& # x0D;& # x0D;这项描述性研究强调了沙特阿拉伯利雅得18岁以上女性与预防性干预措施相关的乳腺癌风险认知。& # x0D;方法:横断面描述性相关设计。一份在线问卷调查了500名18岁及以上的参与者。问卷采用Google Forms设计的自助电子问卷,并通过WhatsApp、twitter等社交媒体渠道进行传播。& # x0D;& # x0D;结果:该研究强调了对乳腺癌的低风险认知和实施预防措施。女性的风险认知与乳房x光检查呈正相关。& # x0D;结论:研究结果将有助于利用乳腺癌风险认知来预测妇女是否采取预防措施。
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引用次数: 0
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Global Journal of Health Science
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