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Concentraciones de vitamina D en mujeres embarazadas y su relación con diabetes gestacional 孕妇维生素D浓度及其与妊娠糖尿病的关系
Q4 Medicine Pub Date : 2020-12-07 DOI: 10.24245/gom.v88i12.4592
Alonso Antonio Collantes-Gutiérrez, T. Romero-Ogawa, Alejandro Morales-López, I. E. D. Santillana
OBJECTIVE: Contrast the levels of vitamin D, in pregnant woman with and without gestational diabetes. MATERIALS AND METHODS: This was an prospective, case control study, were we compared vitamin D levels between two groups, 25 pregnant women with gestational diabetes and, paired by age and IMC, with 25 healthy pregnant control women, who attended to prenatal care, in the department of Gynecology and Obstetrics in the Hospital Universitario de Puebla. RESULTS: Regardless of gestational diabetes, vitamin D deficiency was in 30% patients, and vitamin D insufficiency in the 44%. The vitamin D levels between the patients with gestational diabetes (23.29 ± 9.00 ng/mL) and the healthy patients (26.76 ± 9.33 ng/ mL), didn’t show significant difference (p = 0.14). This study didn’t show association between gestational diabetes and vitamin D deficiency OR = 1.882 (IC95%: 0.518- 6.845; p = 0.333). CONCLUSIONS: Vitamin D levels didn’t relate to gestational diabetes. Pregnant women had high percentages of vitamin D deficiency and insufficiency.
目的:比较妊娠期糖尿病和非妊娠期糖尿病孕妇的维生素D水平。材料和方法:这是一项前瞻性的病例对照研究,我们比较了两组之间的维生素D水平,25名患有妊娠糖尿病的孕妇,以及25名在普埃布拉大学医院妇产科接受产前护理的健康孕妇对照,按年龄和IMC配对。结果:不考虑妊娠糖尿病,30%的患者维生素D缺乏,44%的患者维生素D不足。妊娠期糖尿病患者维生素D水平(23.29±9.00 ng/mL)与正常组(26.76±9.33 ng/mL)差异无统计学意义(p = 0.14)。本研究未发现妊娠期糖尿病与维生素D缺乏之间存在关联OR = 1.882 (IC95%: 0.518- 6.845;P = 0.333)。结论:维生素D水平与妊娠糖尿病无关。孕妇维生素D缺乏和不足的比例很高。
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引用次数: 1
Prevalencia de incontinencia dual 双尿失禁的患病率
Q4 Medicine Pub Date : 2020-12-07 DOI: 10.24245/gom.v88i12.4098
C. R. Jiménez-Vieyra, Lucio Solache-Blanco, J. A. García-Bello
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引用次数: 0
Taponamiento intrauterino con balones hidrostáticos: revisión narrativa 静水球宫内填塞:叙事回顾
Q4 Medicine Pub Date : 2020-12-07 DOI: 10.24245/gom.v88i12.4311
Francisco Javier Robles-Elías, Paulo Felipe Meade-Treviño, José Alfredo Fernández-Lara, Rogelio Robles-Morales
OBJECTIVE: Evaluate de effectiveness of uterine balloons tamponade methods, based on the outcomes of literature reports regarding clinical results, variety, advantages and disadvantages, as to the indications and particularities that is offered by its use. METHODOLOGY: Narrative study of articles indexed in PubMed, Medline, SciELO, and Google Scholar, in English and Spanish language, published between 2008 and April 2020 that contain in their title the keyword postpartum hemorrhage (MeSH) associated with uterine tamponade with hydrostatic balloon, Bakri balloon and uterine atony. RESULTS: 10,984 articles where identified with the key word “obstetric hemorrhage”, when associated with “intrauterine tamponade” they were reduced to 471 references with the final inclusion of 85 after fulfilling the requirements of the authors and 386 articles were excluded. CONCLUSIONS: The use of intrauterine tamponade devices with hydrostatic balloons, due to their high clinical efficiency, accessible cost, easy application, minimal complications, and scarce contraindications, should be a part the management protocols and always be available in all the different scenarios of obstetrical resolution, preserving its primary indication in persistent uterine atony, but expanding the possibilities of its use on placental bed bleeding, placenta previa, and in cases of specific placental acretism with segmental infiltration. It should be considered as a therapeutically approach, earlier post obstetrical event, as in the case of the first uterotonic agent failure, and in selected cases of high-risk for obstetric hemorrhage as a prophylactic procedure.
目的:根据文献报道的临床结果、种类、优缺点以及使用的适应症和特殊性,评估子宫球囊填塞方法的无效性。方法:对2008年至2020年4月期间发表在PubMed、Medline、SciELO和Google Scholar上的英文和西班牙文文章进行叙述性研究,这些文章的标题中包含关键词产后出血(MeSH),与使用静水压球囊、Bakri球囊和子宫收缩相关。结果:10984篇关键词为“产科出血”的文章,当与“宫内填塞”相关时,参考文献减少到471篇,在满足作者要求后最终纳入85篇,386篇被排除在外。结论:使用带静水压球囊的宫内填塞器,由于其临床效率高、成本低、应用方便、并发症少、禁忌症少,应成为管理方案的一部分,并始终适用于所有不同的产科解决方案,保留其持续性子宫张力的主要适应症,但扩大了其在胎盘床出血、前置胎盘以及具有节段性浸润的特定胎盘肢端炎病例中的应用可能性。它应该被视为一种治疗方法,在产后早期发生事件,如第一次子宫内给药失败的情况,以及在选定的产科出血高危病例中作为预防程序。
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引用次数: 0
Marcadores tumorales en cáncer de mama. Revisión sistemática 乳腺癌的肿瘤标志物。系统综述
Q4 Medicine Pub Date : 2020-12-07 DOI: 10.24245/gom.v88i12.4269
Ó. A. Bonilla-Sepúlveda
BACKGROUND: Breast cancer is the most frequent malignant tumor in women around the world. The FDA-approved tumor markers are cancer antigen 15-3 (CA15-3) and carcinoembryonic antigen (CEA), and are frequently used for the detection and control of breast cancer. OBJECTIVE: To present the current available information on the usefulness of tumor markers CA 15-3 and carcinoembryonic antigen in the detection of metastases and their prognostic value in breast cancer. METHODOLOGY: A systematic search of publications in English in the Medline- PubMed database was performed, using the terms: “biomarkers”, “tumor”, “tumor biomarkers”, “marker”, “tumor marker”, “breast neoplasms “,” breast “,” neoplasms “,” cancer “,” mucin-1 “,” ca 15 3 “,” carcinoembryonic antigen “. Original articles, clinical trials, reviews, systematic reviews and meta-analyzes, published between March 28, 2015 and March 25, 2020, were selected to determine the usefulness of the CA 15-3 antigen and carcinoembryonic antigen in breast cancer. RESULTS: Eleven publications that were relevant to determine the usefulness of tumor markers in breast cancer were selected for the writing of this article. CONCLUSIONS: The utility of tumor markers Antigen 15-3 and carcinoembryonic antigen is contradictory, and not fully accepted by oncology associations and inter-national guidelines, however there is evidence that confirms their utility as diagnostic and prognostic markers in breast cancer.
背景:乳腺癌是世界范围内女性最常见的恶性肿瘤。fda批准的肿瘤标志物是癌抗原15-3 (CA15-3)和癌胚抗原(CEA),常用于乳腺癌的检测和控制。目的:介绍肿瘤标志物ca15 -3和癌胚抗原在乳腺癌转移检测中的有效性及其预后价值。方法:系统检索Medline- PubMed数据库中的英文出版物,检索词为:“生物标志物”、“肿瘤”、“肿瘤生物标志物”、“标记物”、“肿瘤标记物”、“乳腺肿瘤”、“肿瘤”、“癌症”、“粘蛋白-1”、“ca 153”、“癌胚抗原”。选取2015年3月28日至2020年3月25日期间发表的原创文章、临床试验、综述、系统评价和荟萃分析,以确定CA 15-3抗原和癌胚抗原在乳腺癌中的有用性。结果:11篇与确定肿瘤标志物在乳腺癌中的有用性相关的出版物被选择用于撰写本文。结论:肿瘤标志物抗原15-3和癌胚抗原的使用是相互矛盾的,肿瘤协会和国际指南没有完全接受它们,但是有证据证实它们作为乳腺癌诊断和预后标志物的效用。
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引用次数: 3
Preservación de la fertilidad: opinión de un grupo de expertos 保护生育能力:专家组的意见
Q4 Medicine Pub Date : 2020-11-13 DOI: 10.24245/gom.v88i11.4605
Víctor Batiza Reséndiz, Ashanti Aguilar Melgar, R. Rojas, Efraín Pérez-Peña, Antonio M Gutiérrez Gutiérrez, Luis Arturo Ruvalcaba Castrellón, C. López-Ortiz, Jorge Alejandro Michel Vergara, Robin Jennifer Shaw Dulin, S. A. B. Muñoz, Luís Hérnandez López, F. G. Rodríguez, P. Esteban, Benito Sánchez Llamas, Ricardo Rodríguez Calderóon, I. M. Rosas
Fertility preservation is the application of medical social preservation considered, in cases of different sexual conceptualization, as the basic legal and ethical aspects.
生育保护是医学社会保护的应用,在不同性别概念化的情况下,被视为基本的法律和伦理方面。
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引用次数: 2
Eosinofilia en sangre y cáncer de ovario: estudio fase I de pruebas diagnósticas 血液嗜酸性粒细胞增多症与卵巢癌:诊断试验I期研究
Q4 Medicine Pub Date : 2020-10-19 DOI: 10.24245/gom.v88i10.3357
Juan Gabriel Álvarez-Sánchez, Ana Teresa Opina-Pérez
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引用次数: 0
Código azul, histerotomía de reanimación en embarazo de término: reporte de un caso 蓝色代码,足月妊娠复苏子宫切除术:一例报告
Q4 Medicine Pub Date : 2020-10-19 DOI: 10.24245/gom.v88i10.3451
Mayela Guadalupe Cuesta-Galindo, Roberto Ruvalcaba-Carrillo, Héctor Manuel Colín-Cortes, José de Jesús Oswaldo Yáñez-Torres, Omar Oswaldo Camarillo-Contreras, Daniel Ely Bravo-Aguirre
BACKGROUND: Cardiorespiratory arrest during pregnancy is a rare event that occurs in 1 in 12,500 to 30,000 pregnancies, with a survival rate of 17-59%. CLINICAL CASE : We report the case of a 23-year-old female patient, late-term preg- nancy and labor. During labor conduction and after spinal analgesia, she presented cardiorespiratory arrest. After the start of basic resuscitation maneuvers, monitoring, and confirmed asystole, advanced maneuvers were started, culminating at 4 minutes with resuscitation hysterotomy and a subsequent spontaneous return of circulation. The patient required immediate post-arrest cares with follow-up and management in the intensive obstetric care unit for one month, after which the patient was discharged with minimal compromise of her superior mental functions; after 3 months of out clinic follow-up, the patient was healthy and her superior functions deemed to have been fully restored. CONCLUSIONS: Due to the ethical implications and characteristics of the pathol- ogy, there are no experimental models to establish measures during cardiopulmonary resuscitation in pregnancy, they are developed based on the review of clinical cases and the study of cardiovascular physiology during pregnancy. In this case report, we conclude that adhering to the established recommendations were associated with a good outcome and prognosis for both mother and child.
背景:妊娠期心肺骤停是一种罕见的事件,每12500-30000例妊娠中就有1例发生,存活率为17-59%。临床病例:我们报告一例23岁女性患者,晚期妊娠和分娩。在分娩期间和脊椎镇痛后,她出现了心肺骤停。在开始基本的复苏操作、监测和确认心搏停止后,开始高级操作,最终在4分钟时进行复苏子宫切开术,随后循环自发恢复。患者需要立即在被捕后进行护理,并在产科重症监护室进行一个月的随访和管理,之后患者出院,对其高级精神功能的损害最小;经过3个月的门诊随访,患者身体健康,上级功能完全恢复。结论:由于病理学的伦理意义和特点,目前还没有建立妊娠期心肺复苏措施的实验模型,这些模型是在回顾临床病例和研究妊娠期心血管生理学的基础上开发的。在本病例报告中,我们得出结论,坚持既定的建议对母亲和儿童都有良好的结果和预后。
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引用次数: 0
Hemorragia obstétrica y rotura uterina por un embarazo intersticial. Reporte de un caso 间质性妊娠引起的产科出血和子宫破裂。病例报告
Q4 Medicine Pub Date : 2020-10-19 DOI: 10.24245/gom.v88i10.4160
Edgar Allan Villagómez-Mendoza, Anabel Tamayo-Iturbe
BACKGROUND: Interstitial ectopic pregnancy occurs in approximately 2.4% of all cases, this tubal portion is located in the proximal segment and shares the muscular portion of the uterus, due to its great myometrial compliance, it facilitates late diagnosis and its clinical presentation is By means of uterine rupture and with it an increase in morbidity and mortality due to obstetric hemorrhage, the risk factors are the same as for tubal ectopic pregnancy, treatment is assessed based on preserving fertility and according to the patient’s clinical setting. CLINICAL CASE: A 31-year-old patient who went to the emergency department for severe and disabling abdominal pain in the hypogastrium, shock index 1.3, with signs of peritoneal irritation, ultrasound was performed, which reported free fluid in the pelvic cavity and Morrison space, extrauterine gestational sac at the level of the left annex, embryo without heartbeat, craniocaudal length of 11 weeks of gestation, exploratory laparotomy was performed, in which hemoperitoneum of 2800 cc was observed, uterine rupture in the right cornual region of approximately 8x6cm, with fetus e integrity of the amniotic sac adjacent to the uterine rupture, the patient reported satisfied parity, and therefore a total abdominal hysterectomy was decided. CONCLUSIONS: Interstitial ectopic pregnancy shares the same risk factors as tubal pregnancy. Today, we have various diagnostic aids, so the cornerstone is timely detection, which will allow conservative treatments to decrease maternal morbidity and mortality.
背景:间质性异位妊娠约占所有病例的2.4%,该输卵管部分位于子宫近端,与子宫肌肉部分共用,由于其对子宫肌层的高度顺应性,有助于晚期诊断,其临床表现为子宫破裂,产科出血导致的发病率和死亡率增加,危险因素与输卵管异位妊娠相同,治疗是根据保留生育能力和患者的临床情况进行评估的。临床病例:一名31岁的患者因下腹部严重和致残性腹痛,休克指数1.3,伴有腹膜刺激迹象而去急诊室,进行了超声检查,报告盆腔和Morrison间隙有游离液体,左侧附件水平的宫外孕囊,胚胎无心跳,妊娠11周,进行了剖腹探查,观察到腹腔积血2800cc,右侧角部子宫破裂约8x6cm,子宫破裂附近羊膜囊的胎儿e完整,患者报告产程满意,因此决定进行全腹子宫切除术。结论:间质性异位妊娠与输卵管妊娠具有相同的危险因素。今天,我们有各种诊断辅助工具,因此基石是及时检测,这将使保守治疗能够降低孕产妇发病率和死亡率。
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引用次数: 0
Conceptos básicos en inmunología de la reproducción: revisión narrativa de la bibliografía 生殖免疫学基础:叙述性文献综述
Q4 Medicine Pub Date : 2020-10-19 DOI: 10.24245/gom.v88i10.4301
J. Rodríguez-Purata, E. Cervantes-Bravo
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引用次数: 0
Tipificación de serotipos del virus del papiloma humano de alto riesgo 高危人乳头状瘤病毒血清型的分型
Q4 Medicine Pub Date : 2020-10-19 DOI: 10.24245/gom.v88i10.3432
G. A. Soto-Fuenzalida, J. Hernández-Hernández, Rosa del Carmen López-Sánchez, Claudia D Aguayo-Millán, L. Villela-Martínez, Matilde Espino-Rodríguez, Ventura Enrique Niño-Parra, R. Ortiz-López
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引用次数: 1
期刊
Ginecologia y obstetricia de Mexico
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