The Sato curved laryngoscope permits a wide view of the hypopharynx by suspending the larynx. As a result, both the examination of the hypopharynx and hypopharyngeal surgery become easier when compared to conventional laryngoscopy. In this study, we report on two cases of hypopharyngeal foreign bodies(fish bones)which were difficult to locate with an upper gastrointestinal endoscope but were readily found and removed safely utilizing the Sato curved laryngoscope.
{"title":"Removal of Hypopharyngeal Foreign Body under Sato Curved Laryngoscope -Report of Two Cases.","authors":"Y. Okazaki, Takeshi Hori, H. Hara, H. Yamashita","doi":"10.5426/LARYNX.26.57","DOIUrl":"https://doi.org/10.5426/LARYNX.26.57","url":null,"abstract":"The Sato curved laryngoscope permits a wide view of the hypopharynx by suspending the larynx. As a result, both the examination of the hypopharynx and hypopharyngeal surgery become easier when compared to conventional laryngoscopy. In this study, we report on two cases of hypopharyngeal foreign bodies(fish bones)which were difficult to locate with an upper gastrointestinal endoscope but were readily found and removed safely utilizing the Sato curved laryngoscope.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126557508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Nagai, K. Nishiyama, Y. Seino, Y. Tabata, M. Okamoto
It is impossible to avoid the deterioration in physical function that accompanies aging. We believe that the aim of anti-aging research is to examine ways to maximize physical function within the human lifespan, rather than to investigate immortality. The first author conducted research at the Connor laboratory (University of Wisconsin) from 2002 to 2004 . The Connor lab investigates histological and physiological changes that accompany aging in the genioglossus and intra-laryngeal muscles, which are important for deglutition and vocalization, respectively. That is, the lab investigates alterations of phonation and deglutition that occur with aging. The first author researched the effects of controlled release of basic fibroblast growth factor with autologous fascia implantation in unilateral laryngeal paralysis. It was hypothesized that this method would induce regeneration of damaged tissue associated with paralysis by providing a scaffold, cells, and growth factors. In experiments using rats, the glottal gap decreased, volume of the paralyzed glottal area increased, and atrophy of the thyroarytenoid muscle improved. These findings suggest that the method may present an attractive option for treating unilateral laryngeal paralysis.
{"title":"A Study of the Muscles of Phonation and Deglutition","authors":"H. Nagai, K. Nishiyama, Y. Seino, Y. Tabata, M. Okamoto","doi":"10.5426/LARYNX.25.36","DOIUrl":"https://doi.org/10.5426/LARYNX.25.36","url":null,"abstract":"It is impossible to avoid the deterioration in physical function that accompanies aging. We believe that the aim of anti-aging research is to examine ways to maximize physical function within the human lifespan, rather than to investigate immortality. The first author conducted research at the Connor laboratory (University of Wisconsin) from 2002 to 2004 . The Connor lab investigates histological and physiological changes that accompany aging in the genioglossus and intra-laryngeal muscles, which are important for deglutition and vocalization, respectively. That is, the lab investigates alterations of phonation and deglutition that occur with aging. The first author researched the effects of controlled release of basic fibroblast growth factor with autologous fascia implantation in unilateral laryngeal paralysis. It was hypothesized that this method would induce regeneration of damaged tissue associated with paralysis by providing a scaffold, cells, and growth factors. In experiments using rats, the glottal gap decreased, volume of the paralyzed glottal area increased, and atrophy of the thyroarytenoid muscle improved. These findings suggest that the method may present an attractive option for treating unilateral laryngeal paralysis.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124866705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Voice Problem after Thyroid Surgery","authors":"K. Kim","doi":"10.5426/LARYNX.25.57","DOIUrl":"https://doi.org/10.5426/LARYNX.25.57","url":null,"abstract":"","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"215 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122911950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Tamura, H. Fukuda, Shinya Okada, M. Shibuya, M. Iida
Vocal fold augmentation with autologous fat has been widely applied for management of glottic insufficien-cy, including vocal fold paresis, vocal fold atrophy, and sulcus vocalis. We describe the techniques in vocal fold augmentation with autologous fat. With cases of unilateral vocal fold paralysis, the needle should be stuck from posterior at the middle of vocal fold membranous region and the essential point is to increase the volume of the entire vocal fold muscle. In sulcus vocalis cases, volume is first increased in the shallow part of the muscle layer. The needle is then withdrawn a little and injection proceeds into the lamina propria mucosa. Autologous fat injection is a relatively safe rehabilitation technique for treating deficiencies in glottal clo-sure. However, excessive use of autologous fat injection can impair voice function. In cases in which there is no improvement in phonation following fat injection, it is important to assess the presence of fat tissues using CT and to determine its effects on wave motion during phonation.
{"title":"Techniques in Vocal Fold Augmentation with Autologous Fat","authors":"E. Tamura, H. Fukuda, Shinya Okada, M. Shibuya, M. Iida","doi":"10.5426/LARYNX.25.74","DOIUrl":"https://doi.org/10.5426/LARYNX.25.74","url":null,"abstract":"Vocal fold augmentation with autologous fat has been widely applied for management of glottic insufficien-cy, including vocal fold paresis, vocal fold atrophy, and sulcus vocalis. We describe the techniques in vocal fold augmentation with autologous fat. With cases of unilateral vocal fold paralysis, the needle should be stuck from posterior at the middle of vocal fold membranous region and the essential point is to increase the volume of the entire vocal fold muscle. In sulcus vocalis cases, volume is first increased in the shallow part of the muscle layer. The needle is then withdrawn a little and injection proceeds into the lamina propria mucosa. Autologous fat injection is a relatively safe rehabilitation technique for treating deficiencies in glottal clo-sure. However, excessive use of autologous fat injection can impair voice function. In cases in which there is no improvement in phonation following fat injection, it is important to assess the presence of fat tissues using CT and to determine its effects on wave motion during phonation.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132367174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kazuo Sakurai, Hisayuki Kato, Tatsuyoshi Okada, T. Yui, M. Shimizu
We performed clinical examination about the usefulness of the superselective intra-arterial chemotherapy for laryngeal cancer. The study group was composed 12 cases of glottic cancer and 9 with supraglottic cancer. Chemotherapy was performed through a catheter inserted into the superior thyroid artery via the forearm artery. The dose of cisplatin was 100 mg/body per infusion session. A radiotherapy doses of 60Gy was performed in all cases. All cases of glottic cancer exhibited a complete response (CR); however, there was local recurrence in two cases. While the survival rate was 100% , the laryngeal preservation rate was 83% .Eight cases of supraglottis cancer demonstrated CR, but one case had partial response (PR). Cervical lymph node recurrence was observed in two cases. The survival rate and the laryngeal preservation rate were 88% . Grade3 mucositis was observed in 12 cases. Superselective intra-arterial chemotherapy for laryngeal cancer was found to be one of the more effective treatments in larynx preservation.
{"title":"Evaluation of Superselective Intra-Arterial Chemotherapy for Laryngeal Cancer","authors":"Kazuo Sakurai, Hisayuki Kato, Tatsuyoshi Okada, T. Yui, M. Shimizu","doi":"10.5426/LARYNX.25.91","DOIUrl":"https://doi.org/10.5426/LARYNX.25.91","url":null,"abstract":"We performed clinical examination about the usefulness of the superselective intra-arterial chemotherapy for laryngeal cancer. The study group was composed 12 cases of glottic cancer and 9 with supraglottic cancer. Chemotherapy was performed through a catheter inserted into the superior thyroid artery via the forearm artery. The dose of cisplatin was 100 mg/body per infusion session. A radiotherapy doses of 60Gy was performed in all cases. All cases of glottic cancer exhibited a complete response (CR); however, there was local recurrence in two cases. While the survival rate was 100% , the laryngeal preservation rate was 83% .Eight cases of supraglottis cancer demonstrated CR, but one case had partial response (PR). Cervical lymph node recurrence was observed in two cases. The survival rate and the laryngeal preservation rate were 88% . Grade3 mucositis was observed in 12 cases. Superselective intra-arterial chemotherapy for laryngeal cancer was found to be one of the more effective treatments in larynx preservation.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"835 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126245996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patients with Japanese cedar pollinosis (JCP) often complain of cough and throat symptoms. We have extensively investigated the prevalence and characteristics of coughing and other symptoms in adults and children with JCP, through questionnaires in the pollen season from 2009 to 2011. According to the questionnaire, 2944% of adults and 31-48% of children complained of coughing. There was neither significant differences in the prevalence of coughing between adults and children, and nor among three season. The severity of the coughing in each patient was almost mild or moderate. Particularly in children, productive cough was significantly more prominent, and throat symptoms were less found than those in adults. In 2009, total nasal symptom score was significantly higher in coughing patients rather than in ones without a cough. However, there were no correlations between coughing and throat symptoms with either adults or children in each year. These results may indicate that coughing in patients with JCP could be attributed to not only laryngeal allergy but also direct influence of nose inflammation. The difference in features of coughing between adults and children suggests the varied pathology in coughing by age.
{"title":"Clinical Cough Features in Adults and Children with Japanese Cedar Pollinosis","authors":"S. Masuda","doi":"10.5426/LARYNX.25.87","DOIUrl":"https://doi.org/10.5426/LARYNX.25.87","url":null,"abstract":"Patients with Japanese cedar pollinosis (JCP) often complain of cough and throat symptoms. We have extensively investigated the prevalence and characteristics of coughing and other symptoms in adults and children with JCP, through questionnaires in the pollen season from 2009 to 2011. According to the questionnaire, 2944% of adults and 31-48% of children complained of coughing. There was neither significant differences in the prevalence of coughing between adults and children, and nor among three season. The severity of the coughing in each patient was almost mild or moderate. Particularly in children, productive cough was significantly more prominent, and throat symptoms were less found than those in adults. In 2009, total nasal symptom score was significantly higher in coughing patients rather than in ones without a cough. However, there were no correlations between coughing and throat symptoms with either adults or children in each year. These results may indicate that coughing in patients with JCP could be attributed to not only laryngeal allergy but also direct influence of nose inflammation. The difference in features of coughing between adults and children suggests the varied pathology in coughing by age.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"218 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116383715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Radiation therapy（RT）has been established as curative treatment for early and locally advanced laryngeal cancer, and excellent local control rate and functional outcomes have been reported especially in patients with T1 or T2 glottic cancer. In contrast, clinical outcomes for locally advanced laryngeal cancer is not sufficient, although RT combined with chemotherapy（CRT）is advocated as a treatment choice in NCCN guideline for T3 disease. There have been no studies directly comparing organ-preservation surgery with nonsurgical or-gan-preservation protocols including chemoradiation therapy for locally advanced-stage laryngeal tumors in a prospective manner with comparable patient groups. In the only prospective randomized study comparing total laryngectomy and nonsurgical organ preservation, the results of Veterans Affairs（VA）Laryngeal Cancer Study demonstrated that disease-specific survival was the same in the 2 groups. The results of the RTOG 9111, comparing 3 arms including CRT, induction chemotherapy, and RT（the VA protocol）and RT alone exhibited that organ preservation was significantly better for the CRT arm, although OS did not differ among the 3 groups. However, it has been suggested that long-term outcomes after CRT might affect clinical outcomes including functional laryngeal preservation and salvage surgery. In this symposium, we will discuss the possibility whether newer strategies such as induction chemotherapy followed by CRT or RT combined with novel biological agents improve clinical outcomes of the landmark intergroup studies.
{"title":"Radiotherapeutic Approaches of Functional Organ Preservation for Laryngeal Cancer","authors":"T. Akimoto","doi":"10.5426/LARYNX.25.29","DOIUrl":"https://doi.org/10.5426/LARYNX.25.29","url":null,"abstract":"Radiation therapy（RT）has been established as curative treatment for early and locally advanced laryngeal cancer, and excellent local control rate and functional outcomes have been reported especially in patients with T1 or T2 glottic cancer. In contrast, clinical outcomes for locally advanced laryngeal cancer is not sufficient, although RT combined with chemotherapy（CRT）is advocated as a treatment choice in NCCN guideline for T3 disease. There have been no studies directly comparing organ-preservation surgery with nonsurgical or-gan-preservation protocols including chemoradiation therapy for locally advanced-stage laryngeal tumors in a prospective manner with comparable patient groups. In the only prospective randomized study comparing total laryngectomy and nonsurgical organ preservation, the results of Veterans Affairs（VA）Laryngeal Cancer Study demonstrated that disease-specific survival was the same in the 2 groups. The results of the RTOG 9111, comparing 3 arms including CRT, induction chemotherapy, and RT（the VA protocol）and RT alone exhibited that organ preservation was significantly better for the CRT arm, although OS did not differ among the 3 groups. However, it has been suggested that long-term outcomes after CRT might affect clinical outcomes including functional laryngeal preservation and salvage surgery. In this symposium, we will discuss the possibility whether newer strategies such as induction chemotherapy followed by CRT or RT combined with novel biological agents improve clinical outcomes of the landmark intergroup studies.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"277 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116559455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to compare the functional biomechanical properties of some injectable phonosurgical biomaterials commonly used for vocal fold augmentation. Linear viscoelastic shear properties of cross-linked hyaluronic acid (HA; Juvederm®), micronized AlloDerm (Cymetra®), 3% bovine collagen (Atelocollagen), and calcium hydroxylapatite (CaHA; Radiesse®) were determined as functions of frequency covering the phonatory range, and compared to those of the human vocal fold cover. Measurements of elastic shear modulus (G’) and dynamic viscosity (η’) were made up to 250 Hz with a controlled-strain simple-shear rheometer. Linear leastsquares regression was conducted to curve-fit log G’ and log η’ versus log frequency, and statistical analysis was performed with one-way ANOVA. There were statistically significant differences in the magnitudes of G’ and η’ among the phonosurgical materials and the normal human vocal fold cover (p<0.01), whereas there was no significant difference (p<0.05) in pairwise comparisons among all materials and the normal vocal fold cover. The rheometric properties of Juvederm and Atelocollagen were the closest match to those of the vocal fold cover. These findings suggest that none of the tested injectable biomaterials are ideal implants for facilitating the functional vibratory performance of the vocal fold cover. Future studies for the development of materials with optimal viscoelastic properties are warranted.
{"title":"Rheology of Vocal Foldx","authors":"M. Kimura, N. Tayama","doi":"10.5426/LARYNX.25.44","DOIUrl":"https://doi.org/10.5426/LARYNX.25.44","url":null,"abstract":"The purpose of this study was to compare the functional biomechanical properties of some injectable phonosurgical biomaterials commonly used for vocal fold augmentation. Linear viscoelastic shear properties of cross-linked hyaluronic acid (HA; Juvederm®), micronized AlloDerm (Cymetra®), 3% bovine collagen (Atelocollagen), and calcium hydroxylapatite (CaHA; Radiesse®) were determined as functions of frequency covering the phonatory range, and compared to those of the human vocal fold cover. Measurements of elastic shear modulus (G’) and dynamic viscosity (η’) were made up to 250 Hz with a controlled-strain simple-shear rheometer. Linear leastsquares regression was conducted to curve-fit log G’ and log η’ versus log frequency, and statistical analysis was performed with one-way ANOVA. There were statistically significant differences in the magnitudes of G’ and η’ among the phonosurgical materials and the normal human vocal fold cover (p<0.01), whereas there was no significant difference (p<0.05) in pairwise comparisons among all materials and the normal vocal fold cover. The rheometric properties of Juvederm and Atelocollagen were the closest match to those of the vocal fold cover. These findings suggest that none of the tested injectable biomaterials are ideal implants for facilitating the functional vibratory performance of the vocal fold cover. Future studies for the development of materials with optimal viscoelastic properties are warranted.","PeriodicalId":126820,"journal":{"name":"THE LARYNX JAPAN","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133014538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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