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Potential use of epigenetic clocks to understand factors associated with aging at the population level and in public health. 利用表观遗传时钟了解与人口老龄化和公共卫生有关的因素的潜力。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000897
José J Martínez-Magaña, Jorge Hurtado-Soriano, Janitza L Montalvo-Ortiz, Juan C Gomez-Verjan
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引用次数: 0
Characteristics and health conditions in older people who work in Mexico. A comparative analysis between cohorts and sex. 在墨西哥工作的老年人的特征和健康状况。不同群体和性别之间的比较分析。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000900
Rosa E García-Chanes, Abigail V Rojas-Huerta, Hedalid Tolentino-Arellano

Background: The study of the work and health of older adults is limited but relevant considering that the living and health conditions in which they age are not the best in Mexico, given the job insecurity that does not access to decent contributory pensions.

Objective: To analyse the differences in the sociodemographic, labour and health conditions characteristics of two cohorts of older people aged 65 to 74 years who are employed in the labour market.

Material and methods: Analysis of the National Study of Health and Aging in Mexico for 2001 and 2021 of sociodemographic and work characteristics and health conditions by cohort and sex. Logistic regression models, whose dependent variable was the birth cohort, were estimated.

Results: 1,115 people from 2001 and 1,189 from 2021 between 65 and 74 years old who worked the week before the study were included. By sex and cohort, findings are presented.

Conclusions: Although the schooling of older people in the most recent cohort has increased, women face more precarious working conditions and a higher prevalence of disability.

背景:对老年人工作和健康的研究是有限的,但考虑到在墨西哥,老年人的生活和健康条件并不是最好的,因为他们的工作不稳定,无法获得体面的缴费养老金:分析在劳动力市场就业的 65 至 74 岁两组老年人在社会人口、劳动和健康状况特征方面的差异:对 2001 年和 2021 年墨西哥全国健康与老龄化研究中按组群和性别分列的社会人口特征、工作特征和健康状况进行分析。对因变量为出生队列的逻辑回归模型进行了估计:研究对象包括 2001 年的 1 115 人和 2021 年的 1 189 人,他们都是在研究前一周工作的 65 至 74 岁的老年人。研究结果按性别和出生组群分列:尽管最近一批老年人的入学率有所提高,但妇女面临的工作条件更不稳定,残疾发生率更高。
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引用次数: 0
Index of functional impairment in older people: analysis by ethnicity. 老年人功能障碍指数:按种族分析。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000898
José L Castrejón-Caballero, Rosa E García-Chanes

Background: Aging in Mexico is heterogeneous considering the ethnic diversity and social inequality that prevails. The condition of ethnicity allows us to delve deeper into the social and health inequalities that do not allow for healthy aging.

Objective: The objective of this article is to compare the levels of functionality of older people by ethnicity and its associated factors in Mexico.

Material and methods: People aged 60 years and over were selected from the 2020 Census sample, grouping according to their ethnic status (Indigenous, Afro-Mexican and non-Indigenous and non-afro Mexican). As a dependent variable, the Functional Impairment Index (IDF) was constructed with principal components analysis, using the battery of disability questions; Generalized linear models were performed to analyse the factors associated by ethnicity status.

Results: Indigenous older people have higher IDF values, followed by Afro-Mexican. Indigenous women and those who live in rural areas have higher values of functional impairment.

Conclusions: It is necessary to address the needs of the older Indigenous and Afro-Mexican population who face an old age with greater social disadvantage and functional deterioration.

背景:考虑到种族多样性和社会不平等的普遍存在,墨西哥的老龄化问题十分复杂。种族条件使我们能够更深入地研究社会和健康方面的不平等,这些不平等导致了健康老龄化:本文旨在比较墨西哥不同种族老年人的功能水平及其相关因素:从 2020 年人口普查样本中选取了 60 岁及以上的老年人,根据其种族状况(土著、非洲裔墨西哥人、非土著和非非洲裔墨西哥人)进行分组。作为因变量,利用主成分分析法构建了功能损伤指数(IDF),并使用残疾问题电池;采用广义线性模型分析了与种族状况相关的因素:结果:土著老年人的 IDF 值较高,其次是非裔墨西哥人。结果:土著老年人的 IDF 值较高,其次是非裔墨西哥人,土著妇女和居住在农村地区的老年人的功能障碍值较高:有必要满足土著和非裔墨西哥老年人口的需求,因为他们在老年时面临着更大的社会劣势和功能衰退。
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引用次数: 0
Reflections on anxiety and depression disorders in pandemic times. 对大流行病时代焦虑症和抑郁症的思考。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000870
David Rivas-Sucari, José L Rodríguez-Eguizabal, Henry C Rivas-Sucari
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引用次数: 0
The cascade of access to the public health system in older Mexican adults and associated factors. 墨西哥老年人利用公共卫生系统的连锁反应及相关因素。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.24000074
Héctor García-Hernández, Mario U Pérez-Zepeda, Lorena Parra-Rodríguez, Carmen García-Peña

Background: Information about access to the public health system for elders is lacking in Mexico.

Objective: Develop a cascade of access to the public health system in Mexican older adults and identify factors that could promote or hinder it.

Material and methods: A cross-sectional analysis using data from the 2018, 2021, and 2022 National Health and Nutrition Survey rounds. A cascade of access to the public health system was constructed. Multivariate regression models were performed to identify related factors.

Results: 43.33%, 40.85%, and 43.79% of older adults had access to the public health system in 2018, 2021, and 2022, respectively. In 2018, frailty increased 2.419 times the probability of having access. While, being married or in union, being literate, and living in an urban residency increased access in 2021 and 2022.

Conclusions: There are persistently low levels of public healthcare access among older Mexican adults. Frailty elders had more probability of having access in 2018. Seguro Popular might have promoted access by overcoming organizational obstacles from the public system and surpassing sociodemographic barriers. After its elimination, sociodemographic variables became more relevant in promoting or reducing access.

背景:墨西哥缺乏有关老年人使用公共卫生系统的信息:建立墨西哥老年人利用公共卫生系统的层级关系,并确定可能促进或阻碍这一关系的因素:使用2018年、2021年和2022年国家健康和营养调查的数据进行横截面分析。构建了进入公共卫生系统的级联。通过多变量回归模型确定相关因素:2018年、2021年和2022年,分别有43.33%、40.85%和43.79%的老年人使用了公共卫生系统。在 2018 年,体弱增加了 2.419 倍的使用概率。而在 2021 年和 2022 年,已婚或同居、识字以及居住在城市的老年人获得公共卫生服务的概率增加:墨西哥老年人获得公共医疗服务的比例一直很低。在 2018 年,体弱的老年人更有可能获得医疗服务。Seguro Popular可能通过克服来自公共系统的组织障碍和超越社会人口障碍来促进获取。在取消该计划后,社会人口变量在促进或减少就医机会方面变得更加重要。
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引用次数: 0
Burden of disease in older adults in Mexico, 1990-2022: time trends and challenges for the health system. 1990-2022 年墨西哥老年人的疾病负担:时间趋势和卫生系统面临的挑战。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000901
Christian Razo, Rafael Lozano, Luis M Gutiérrez-Robledo

Background: Aging, urbanization, and lifestyle changes have fueled the non-communicable diseases (NCDs) epidemic.

Objective: Assess mortality, disability, risk factors and life expectancy in people aged ≥60 years (LE-60) in Mexico from 1990-2022 using estimates from the Global Burden of Diseases, Injuries and Risk factors study.

Material and methods: Health loss/gain in terms of disability-adjusted life years, risk factors, LE-60 and healthy life expectancy (HALE-60) by sex and state were analyzed.

Results: NCDs and metabolic risk factors were the main contributors of health loss, noting a high prevalence of non-lethal conditions related to functional decline (vision and hearing), oral conditions, and chronic pain (back pain and osteoarthritis). All-cause mortality and disability rates decreased among men and women while LE-60 and HALE-60 increased from 1990-2022, with state-level variations. States with greater development and healthcare had higher LE-60 and HALE-60.

Conclusions: LE-60 increases were not accompanied by reductions in disability due to functional decline, highlighting the need for healthcare strategies to enhance healthy aging.

背景:老龄化、城市化和生活方式的改变加剧了非传染性疾病的流行:老龄化、城市化和生活方式的改变助长了非传染性疾病(NCDs)的流行:利用全球疾病、伤害和风险因素负担研究的估计数据,评估 1990-2022 年墨西哥≥60 岁人群(LE-60)的死亡率、残疾率、风险因素和预期寿命。材料与方法:分析按性别和州分列的残疾调整寿命年数、风险因素、LE-60 和健康预期寿命(HALE-60)方面的健康损失/收益:结果:非传染性疾病和代谢风险因素是造成健康损失的主要原因,与功能衰退(视力和听力)、口腔疾病和慢性疼痛(背痛和骨关节炎)相关的非致命性疾病发病率较高。1990-2022 年间,男性和女性的全因死亡率和残疾率均有所下降,而 LE-60 和 HALE-60 则有所上升,但各州之间存在差异。发展和医疗水平较高的州,LE-60 和 HALE-60 较高:结论:LE-60 的增加并没有伴随着功能衰退导致的残疾的减少,这突出表明需要采取医疗保健策略来促进健康老龄化。
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引用次数: 0
Combating ageism: awareness and best practices in healthcare for older people. 打击老龄歧视:老年人医疗保健方面的认识和最佳做法。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000903
Victoria González-García, Claudia L Chávez-García, Jennifer E Girón-Castillo, Brayan Reyes-Cedeño, Eduardo Sosa-Tinoco
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引用次数: 0
Diagnosis of nutritional status, dyslipidemia and associated risk factors in indigenous Yaqui schoolchildren. 诊断土著雅基学童的营养状况、血脂异常和相关风险因素。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000856
Norma A Dórame-López, Leticia E Bobadilla-Tapia, Alejandra Tapia-Villaseñor, Ana C Gallegos-Aguilar, Araceli Serna-Gutiérrez, Heliodoro Alemán-Mateo, Julián Esparza-Romero

Background: Malnutrition is a global problem that affects schoolchildren and can increase the risk of diseases in adulthood. Adult members of the Yaqui Indigenous group have been shown to have serious health problems, and Yaqui schoolchildren could therefore find themselves in a similar situation.

Objective: To evaluate the nutritional status, lipid profile and associated factors in a sample of Yaqui schoolchildren.

Material and methods: A total of 109 Yaqui schoolchildren who lived in their localities of origin were recruited. Anthropometric measurements were carried out, a venous blood sample was extracted in fasting conditions, and several questionnaires were applied.

Results: The prevalence of overweight/obesity was 38.5%, with no cases of chronic malnutrition being recorded; 38.6% of the children had dyslipidemia. Fiber consumption was a protective factor against overweight/obesity, while fat intake was a risk factor. The physical activity score was found to be a protective factor against dyslipidemia, and the risk factors were BMI-for-age Z-scores, waist circumference, family history of dyslipidemia, educational level, and permanent employment.

Conclusions: Yaqui schoolchildren equally suffer from a high proportion of overweight/obesity and dyslipidemia. The associated factors may be useful for the design of contextualized interventions for this population.

背景:营养不良是影响学龄儿童的全球性问题,会增加他们成年后患病的风险。亚基土著群体的成年成员已被证明存在严重的健康问题,因此亚基学童也可能面临类似的情况:评估雅基学童样本的营养状况、血脂状况及相关因素:共招募了 109 名居住在原籍的雅基学童。对他们进行了人体测量,在空腹状态下抽取了静脉血样本,并进行了几种问卷调查:结果:超重/肥胖率为 38.5%,无慢性营养不良病例记录;38.6% 的儿童患有血脂异常。纤维摄入量是防止超重/肥胖的保护因素,而脂肪摄入量则是风险因素。体力活动得分是血脂异常的保护因素,而风险因素则是体重指数-年龄 Z 值、腰围、血脂异常家族史、教育水平和长期就业:结论:亚基学童同样患有高比例的超重/肥胖症和血脂异常。相关因素可能有助于为这一人群设计因地制宜的干预措施。
{"title":"Diagnosis of nutritional status, dyslipidemia and associated risk factors in indigenous Yaqui schoolchildren.","authors":"Norma A Dórame-López, Leticia E Bobadilla-Tapia, Alejandra Tapia-Villaseñor, Ana C Gallegos-Aguilar, Araceli Serna-Gutiérrez, Heliodoro Alemán-Mateo, Julián Esparza-Romero","doi":"10.24875/GMM.M24000856","DOIUrl":"https://doi.org/10.24875/GMM.M24000856","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is a global problem that affects schoolchildren and can increase the risk of diseases in adulthood. Adult members of the Yaqui Indigenous group have been shown to have serious health problems, and Yaqui schoolchildren could therefore find themselves in a similar situation.</p><p><strong>Objective: </strong>To evaluate the nutritional status, lipid profile and associated factors in a sample of Yaqui schoolchildren.</p><p><strong>Material and methods: </strong>A total of 109 Yaqui schoolchildren who lived in their localities of origin were recruited. Anthropometric measurements were carried out, a venous blood sample was extracted in fasting conditions, and several questionnaires were applied.</p><p><strong>Results: </strong>The prevalence of overweight/obesity was 38.5%, with no cases of chronic malnutrition being recorded; 38.6% of the children had dyslipidemia. Fiber consumption was a protective factor against overweight/obesity, while fat intake was a risk factor. The physical activity score was found to be a protective factor against dyslipidemia, and the risk factors were BMI-for-age Z-scores, waist circumference, family history of dyslipidemia, educational level, and permanent employment.</p><p><strong>Conclusions: </strong>Yaqui schoolchildren equally suffer from a high proportion of overweight/obesity and dyslipidemia. The associated factors may be useful for the design of contextualized interventions for this population.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 1","pages":"53-61"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter about the article "Genes related to hereditary microphthalmia and anophthalmia". 关于文章 "遗传性小眼症和无眼症的相关基因 "的来信。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000852
Maleny E Roque-Camacho
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引用次数: 0
Impact of previous percutaneous coronary intervention on angiographic and clinical outcomes in patients with ST-segment elevation myocardial infarction. 既往经皮冠状动脉介入治疗对 ST 段抬高型心肌梗死患者血管造影和临床结果的影响。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000847
Alejandro Sierra-González de Cossío, Diego Araiza-Garaygordobil, Nitzha A Nájera-Rojas, Alma P Alonso-Bringas, Mariana Robles-Ledesma, José Luis Briseño-de la Cruz, Rodrigo Gopar-Nieto, Héctor González-Pacheco, Daniel Sierra-Lara-Martínez, Alexandra Arias-Mendoza

Background: The prognosis of patients with ST-segment elevation myocardial infarction (STEMI) and previous percutaneous coronary intervention (PCI) is uncertain.

Objective: To evaluate if previous PCI in patients with STEMI increases the risk of major cardiovascular events, and if final epicardial blood flow differs according to the reperfusion strategy.

Material and methods: Observational, longitudinal, comparative sub-study of the PHASE-MX trial that included patients with STEMI and reperfusion within 12 hours of symptom onset, who were classified according to their history of PCI. The occurrence of the composite primary endpoint (cardiovascular death, re-infarction, congestive heart failure and cardiogenic shock) within 30 days was evaluated using Kaplan-Meier estimates, log-rank test and Cox proportional hazards model. Epicardial blood flow was assessed using the TIMI grading system after reperfusion.

Results: A total of 935 patients were included; 85.6% were males and 6.9% had a history of PCI; 53% underwent pharmacoinvasive therapy, and 47%, primary PCI. The incidence of the composite primary endpoint at 30 days in patients with a history of PCI was 9.8% vs 13.3% in those with no previous PCI (p = 0.06). Among the patients with previous PCI, 87.1% reached a final TIMI grade 3 flow after primary PCI vs. 75% in the group with pharmacoinvasive strategy (p = 0.235).

Conclusions: A history of PCI does not increase the risk of major cardiovascular events at 30 days; however, it impacted negatively on the final angiographic blood flow of patients that received pharmacoinvasive therapy (compared to primary PCI).

背景:ST段抬高型心肌梗死(STEMI)和既往经皮冠状动脉介入治疗(PCI)患者的预后尚不确定:目的:评估 STEMI 患者既往接受过 PCI 是否会增加主要心血管事件的风险,以及最终心外膜血流是否会因再灌注策略的不同而有所差异:PHASE-MX试验的观察性、纵向、比较性子研究,包括STEMI患者和症状出现后12小时内进行再灌注的患者,这些患者根据其PCI史进行分类。采用卡普兰-梅耶估计、对数秩检验和考克斯比例危险模型评估了30天内复合主要终点(心血管死亡、再梗死、充血性心力衰竭和心源性休克)的发生率。再灌注后采用TIMI分级系统评估心外膜血流:共纳入935名患者;85.6%为男性,6.9%有PCI病史;53%接受了药物介入治疗,47%接受了初级PCI治疗。既往接受过 PCI 治疗的患者 30 天内复合主要终点的发生率为 9.8%,而既往未接受过 PCI 治疗的患者为 13.3%(P = 0.06)。在既往有PCI史的患者中,87.1%的患者在初级PCI术后达到最终TIMI 3级血流,而采用药物介入策略的患者为75%(P = 0.235):PCI史不会增加30天内发生主要心血管事件的风险;但它对接受药物介入治疗的患者(与初级PCI相比)的最终血管造影血流有负面影响。
{"title":"Impact of previous percutaneous coronary intervention on angiographic and clinical outcomes in patients with ST-segment elevation myocardial infarction.","authors":"Alejandro Sierra-González de Cossío, Diego Araiza-Garaygordobil, Nitzha A Nájera-Rojas, Alma P Alonso-Bringas, Mariana Robles-Ledesma, José Luis Briseño-de la Cruz, Rodrigo Gopar-Nieto, Héctor González-Pacheco, Daniel Sierra-Lara-Martínez, Alexandra Arias-Mendoza","doi":"10.24875/GMM.M24000847","DOIUrl":"10.24875/GMM.M24000847","url":null,"abstract":"<p><strong>Background: </strong>The prognosis of patients with ST-segment elevation myocardial infarction (STEMI) and previous percutaneous coronary intervention (PCI) is uncertain.</p><p><strong>Objective: </strong>To evaluate if previous PCI in patients with STEMI increases the risk of major cardiovascular events, and if final epicardial blood flow differs according to the reperfusion strategy.</p><p><strong>Material and methods: </strong>Observational, longitudinal, comparative sub-study of the PHASE-MX trial that included patients with STEMI and reperfusion within 12 hours of symptom onset, who were classified according to their history of PCI. The occurrence of the composite primary endpoint (cardiovascular death, re-infarction, congestive heart failure and cardiogenic shock) within 30 days was evaluated using Kaplan-Meier estimates, log-rank test and Cox proportional hazards model. Epicardial blood flow was assessed using the TIMI grading system after reperfusion.</p><p><strong>Results: </strong>A total of 935 patients were included; 85.6% were males and 6.9% had a history of PCI; 53% underwent pharmacoinvasive therapy, and 47%, primary PCI. The incidence of the composite primary endpoint at 30 days in patients with a history of PCI was 9.8% vs 13.3% in those with no previous PCI (p = 0.06). Among the patients with previous PCI, 87.1% reached a final TIMI grade 3 flow after primary PCI vs. 75% in the group with pharmacoinvasive strategy (p = 0.235).</p><p><strong>Conclusions: </strong>A history of PCI does not increase the risk of major cardiovascular events at 30 days; however, it impacted negatively on the final angiographic blood flow of patients that received pharmacoinvasive therapy (compared to primary PCI).</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 1","pages":"45-52"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Gaceta medica de Mexico
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