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Cultural context and self-care impact on medical students' quality of life. A mixed-methods approach. 文化背景和自我保健对医学生生活质量的影响。混合方法。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000860
Iván J Canales-Gómez, Blanca M Torres-Mendoza

Background: Medical education can make it difficult for students to take actions to improve their health.

Objective: To evaluate the influence of the university context on self-care behaviors and quality of life.

Material and methods: A mixed-methods approach was used, with surveys being combined to assess self-care and quality of life, with in-depth interviews to explore cultural influences and perceptions. Statistical analysis and qualitative data coding were carried out, with methods being integrated through network analysis.

Results: Self-care scores exceeded 50 points, and quality of life scores exceeded 60 points. Medical students' context is shaped by motivations, expectations, skills, and goals that influence identity formation and contribute to the medical profession.

Conclusions: There is a positive connection between self-care practices and quality of life. However, academic stress can potentially disrupt self-care routines. Furthermore, an association between obesity and a decrease in quality of life stands out, which emphasizes the need for health promotion actions.

背景:医学教育可能使学生难以采取行动改善自身健康:评估大学环境对自我保健行为和生活质量的影响:采用混合方法,结合调查评估自我保健和生活质量,并通过深入访谈探讨文化影响和观念。进行了统计分析和定性数据编码,并通过网络分析对方法进行了整合:结果:自我保健得分超过 50 分,生活质量得分超过 60 分。医学生的背景由动机、期望、技能和目标塑造,这些因素影响着身份的形成,并对医学专业做出贡献:结论:自我保健实践与生活质量之间存在积极的联系。然而,学业压力可能会扰乱自我保健的常规做法。此外,肥胖与生活质量下降之间的联系也很突出,这强调了采取健康促进行动的必要性。
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引用次数: 0
Prevalence of Microsatellite Instability in Gastric and Gastroesophageal Junction Cancer patients from a Latin American Country. 拉丁美洲国家胃和胃食管结癌患者微卫星不稳定的患病率。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.24000128
Alejandro González-Motta, Gabriela Negrete-Tobar, Oscar A Messa-Botero, Juliana Pineda-Ortega, Isabella Garciandía, Juan S Álvarez-Martiínez, Natalia Londoño-De Vivero, Ricardo Bruges-Maya

Background: In Colombia, gastric cancer is fifth in incidence (12.8 cases per 100,000) and third in mortality (9.9 cases per 100,000). Microsatellite instability (MSI), a phenotype in gastric cancer treatment, lacks comprehensive exploration in Colombian and Hispanic/Latino populations. Data scarcity hinders immunotherapy approval in middle-income countries.

Objective: Characterize the prevalence of MSI phenotype in Colombian patients with gastric and gastroesophageal junction cancer.

Materials and methods: We measured MLH-1, MSH-2, MSH-6, and PMS-2 expression in tumor pathology by immunohistochemistry markers. We conducted descriptive analysis and Fisher's test to identify associations for MSI expression.

Results: Final sample size was 106 patients, mean age of 62.5 years (25-93 ± 14.2). Prevalence of MSI was 12.26% (n = 13). We found an association between older age and positive MSI (p = 0.0042), as well as with non-diffuse histologic subtypes (p = 0.019).

Conclusion: Prior studies report 22% MSI phenotype prevalence in gastric tumors, mostly in developed countries, excluding Hispanic/Latino populations. Identifying the prevalence of MSI in our population as 12.26% could pave the way for approving immune blockade drugs as a treatment option for these patients in Latin American countries. Our data could be utilized to conduct cost-utility studies in support of this.

背景:在哥伦比亚,胃癌的发病率排名第五(每10万人12.8例),死亡率排名第三(每10万人9.9例)。微卫星不稳定性(Microsatellite instability, MSI)是胃癌治疗中的一种表型,在哥伦比亚和西班牙/拉丁裔人群中缺乏全面的探索。数据匮乏阻碍了中等收入国家批准免疫疗法。目的:探讨哥伦比亚胃癌和胃食管结癌患者中MSI表型的患病率。材料和方法:采用免疫组织化学方法检测肿瘤病理组织中mmh -1、MSH-2、MSH-6和PMS-2的表达。我们进行了描述性分析和Fisher检验来确定MSI表达的相关性。结果:最终样本量106例,平均年龄62.5岁(25-93±14.2)。MSI患病率为12.26% (n = 13)。我们发现年龄与MSI阳性(p = 0.0042)以及非弥漫性组织学亚型(p = 0.019)之间存在关联。结论:先前的研究报告MSI表型在胃肿瘤中的患病率为22%,主要发生在发达国家,不包括西班牙裔/拉丁裔人群。确定我们人群中MSI的患病率为12.26%,可以为批准免疫阻断药物作为拉丁美洲国家这些患者的治疗选择铺平道路。我们的数据可以用来进行成本效用研究来支持这一点。
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引用次数: 0
Reply to the letter about the article "Cycle threshold and viral load in SARS-CoV-2-infected patients in Sonora, Mexico". 回复有关 "墨西哥索诺拉州 SARS-CoV-2 感染者的周期阈值和病毒载量 "一文的来信。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000850
Denica Cruz-Loustaunau, Gerardo Álvarez-Hernández, Ma Del Carmen Candia-Plata, Marcia Leyva-Gastelum
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引用次数: 0
Authors' reply to the letter about the article "Food addiction behavior in newly-diagnosed patients with type 2 diabetes". 作者对有关 "新诊断的 2 型糖尿病患者的食物成瘾行为 "一文的回信。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000862
Pilar Lavielle, Rita A Gómez-Díaz, A Leticia Valdéz-González, Niels H Wacher
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引用次数: 0
Missed opportunities for prevention of congenital syphilis. 错失预防先天性梅毒的良机。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000869
Eduardo A Hernández-Muñoz, Jessica Gil-Lozada, Jorge B Díaz-Ramírez, Eugenio V Zavala-Sánchez, Elia Lara-Lona

Background: The WHO presented the initiative: "Global elimination of congenital syphilis (CS): rationale and strategies for action". It establishes that CS is a preventable disease that can be eliminated.

Objective: To estimate the proportion of missed opportunities for prevention (MOP) of (CS).

Material and methods: Cross-sectional study. We studied women with children with confirmed diagnosis of CS (NOM-039-SSA2-2002) in the Mexican Social Security Institute in Jalisco from 01/01/2016 to 08/01/2022. The clinical records of the mother, the newborn and the epidemiological study (ES) were reviewed. Each case was classified into one of the MOP categories.

Results: 52 cases were reported: 46.2 % (n = 24) were ruled out, 34.6 % (n = 18) confirmed, 15.4 % (n = 8) unknown and 3.8 % (n = 2) probable cases. The HIV test was performed in 61.1 % (n = 11) and syphilis in 72.2 % (n = 13) of the mothers. The MOP in 27.8 % (n = 5) was inadequate treatment or omission of maternal treatment despite a timely diagnosis of syphilis. Treatment was inadequate in 63.6 % (n = 7) of the women who received it.

Conclusion: The classification of MOP identifies gaps in CS prevention and can guide stakeholders, policy makers and public health prevention programs to reduce the incidence of CS.

背景:世卫组织提出了 "全球消除先天性梅毒(CS):理由和行动战略 "倡议。该倡议认为先天性梅毒是一种可预防、可消除的疾病:材料与方法:横断面研究:横断面研究。我们对哈利斯科州墨西哥社会保障局在 2016 年 1 月 1 日至 2022 年 1 月 8 日期间确诊为 CS(NOM-039-SSA2-2002)的有子女妇女进行了研究。对母亲、新生儿和流行病学研究(ES)的临床记录进行了审查。每个病例都被归入澳门葡京娱乐网址类别之一:结果:共报告了 52 个病例:结果:共报告了 52 例病例:46.2%(24 例)排除,34.6%(18 例)确诊,15.4%(8 例)未知,3.8%(2 例)可能。61.1%(11 人)的母亲进行了艾滋病毒检测,72.2%(13 人)的母亲进行了梅毒检测。27.8%(n=5)的澳门巴黎人娱乐官网是治疗不当,或尽管及时诊断出梅毒,但产妇仍未接受治疗。在接受治疗的产妇中,63.6%(n = 7)的产妇治疗不当:梅毒澳门巴黎人娱乐官网的分类确定了CS预防中的差距,可指导利益相关者、政策制定者和公共卫生预防计划降低CS的发病率。
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引用次数: 0
Potential use of epigenetic clocks to understand factors associated with aging at the population level and in public health. 利用表观遗传时钟了解与人口老龄化和公共卫生有关的因素的潜力。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000897
José J Martínez-Magaña, Jorge Hurtado-Soriano, Janitza L Montalvo-Ortiz, Juan C Gomez-Verjan
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引用次数: 0
Characteristics and health conditions in older people who work in Mexico. A comparative analysis between cohorts and sex. 在墨西哥工作的老年人的特征和健康状况。不同群体和性别之间的比较分析。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000900
Rosa E García-Chanes, Abigail V Rojas-Huerta, Hedalid Tolentino-Arellano

Background: The study of the work and health of older adults is limited but relevant considering that the living and health conditions in which they age are not the best in Mexico, given the job insecurity that does not access to decent contributory pensions.

Objective: To analyse the differences in the sociodemographic, labour and health conditions characteristics of two cohorts of older people aged 65 to 74 years who are employed in the labour market.

Material and methods: Analysis of the National Study of Health and Aging in Mexico for 2001 and 2021 of sociodemographic and work characteristics and health conditions by cohort and sex. Logistic regression models, whose dependent variable was the birth cohort, were estimated.

Results: 1,115 people from 2001 and 1,189 from 2021 between 65 and 74 years old who worked the week before the study were included. By sex and cohort, findings are presented.

Conclusions: Although the schooling of older people in the most recent cohort has increased, women face more precarious working conditions and a higher prevalence of disability.

背景:对老年人工作和健康的研究是有限的,但考虑到在墨西哥,老年人的生活和健康条件并不是最好的,因为他们的工作不稳定,无法获得体面的缴费养老金:分析在劳动力市场就业的 65 至 74 岁两组老年人在社会人口、劳动和健康状况特征方面的差异:对 2001 年和 2021 年墨西哥全国健康与老龄化研究中按组群和性别分列的社会人口特征、工作特征和健康状况进行分析。对因变量为出生队列的逻辑回归模型进行了估计:研究对象包括 2001 年的 1 115 人和 2021 年的 1 189 人,他们都是在研究前一周工作的 65 至 74 岁的老年人。研究结果按性别和出生组群分列:尽管最近一批老年人的入学率有所提高,但妇女面临的工作条件更不稳定,残疾发生率更高。
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引用次数: 0
Index of functional impairment in older people: analysis by ethnicity. 老年人功能障碍指数:按种族分析。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000898
José L Castrejón-Caballero, Rosa E García-Chanes

Background: Aging in Mexico is heterogeneous considering the ethnic diversity and social inequality that prevails. The condition of ethnicity allows us to delve deeper into the social and health inequalities that do not allow for healthy aging.

Objective: The objective of this article is to compare the levels of functionality of older people by ethnicity and its associated factors in Mexico.

Material and methods: People aged 60 years and over were selected from the 2020 Census sample, grouping according to their ethnic status (Indigenous, Afro-Mexican and non-Indigenous and non-afro Mexican). As a dependent variable, the Functional Impairment Index (IDF) was constructed with principal components analysis, using the battery of disability questions; Generalized linear models were performed to analyse the factors associated by ethnicity status.

Results: Indigenous older people have higher IDF values, followed by Afro-Mexican. Indigenous women and those who live in rural areas have higher values of functional impairment.

Conclusions: It is necessary to address the needs of the older Indigenous and Afro-Mexican population who face an old age with greater social disadvantage and functional deterioration.

背景:考虑到种族多样性和社会不平等的普遍存在,墨西哥的老龄化问题十分复杂。种族条件使我们能够更深入地研究社会和健康方面的不平等,这些不平等导致了健康老龄化:本文旨在比较墨西哥不同种族老年人的功能水平及其相关因素:从 2020 年人口普查样本中选取了 60 岁及以上的老年人,根据其种族状况(土著、非洲裔墨西哥人、非土著和非非洲裔墨西哥人)进行分组。作为因变量,利用主成分分析法构建了功能损伤指数(IDF),并使用残疾问题电池;采用广义线性模型分析了与种族状况相关的因素:结果:土著老年人的 IDF 值较高,其次是非裔墨西哥人。结果:土著老年人的 IDF 值较高,其次是非裔墨西哥人,土著妇女和居住在农村地区的老年人的功能障碍值较高:有必要满足土著和非裔墨西哥老年人口的需求,因为他们在老年时面临着更大的社会劣势和功能衰退。
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引用次数: 0
Reply to the letter "New perspectives in the management of SARS-CoV-2 Pirola variants and the development of long COVID syndrome: anti-Ro52/TRIM21 antibodies and qRT-PCR". 回复“SARS-CoV-2 Pirola变异体管理和长冠状病毒综合征发展的新视角:抗ro52 /TRIM21抗体和qRT-PCR”
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000923
Sergio A Ramírez-García, Luis A Hernández-Osorio, Elva Montero-Toledo
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引用次数: 0
The importance of preserving the original names of institutions: a case against translation. 保留原机构名称的重要性:一个反对翻译的案例。
IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 DOI: 10.24875/GMM.M24000920
Aldo Barajas-Ochoa, Antonio Cisneros-Barrios, Cesar Ramos-Remus
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引用次数: 0
期刊
Gaceta medica de Mexico
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