T. Olesiński, M. Szpakowski, W. Każmierczak, U. Sułkowska, A. Rutkowski
{"title":"Evaluation of the incidence of splenic hilar lymph node metastasis in patients operated on for esophagogastric junction cancer","authors":"T. Olesiński, M. Szpakowski, W. Każmierczak, U. Sułkowska, A. Rutkowski","doi":"10.5603/njo.2023.0016","DOIUrl":"https://doi.org/10.5603/njo.2023.0016","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121124275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Solitary cutaneous focal mucinosis during immunotherapy for melanoma","authors":"P. Baran, W. Wysocki","doi":"10.5603/njo.a2023.0007","DOIUrl":"https://doi.org/10.5603/njo.a2023.0007","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116590576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
While lung cancer mortality has been decreasing in many countries due to tobacco control efforts, at least one quarter of global lung cancer cases occur among non-smokers. There is growing attention being paid to the role of environmental exposures, such as radon and air pollution, in lung cancer. Additionally, recent research efforts have sought to elucidate the distinct characteristics of and mechanisms involved in lung cancer among never smokers. Continued research on non-smoking lung cancer is critical to identifying new opportunities for intervention and addressing the global burden of lung cancer.
{"title":"Non-smoking lung cancer and environmental exposure","authors":"M. Parascandola","doi":"10.5603/njo.a2023.0012","DOIUrl":"https://doi.org/10.5603/njo.a2023.0012","url":null,"abstract":"While lung cancer mortality has been decreasing in many countries due to tobacco control efforts, at least one quarter of global lung cancer cases occur among non-smokers. There is growing attention being paid to the role of environmental exposures, such as radon and air pollution, in lung cancer. Additionally, recent research efforts have sought to elucidate the distinct characteristics of and mechanisms involved in lung cancer among never smokers. Continued research on non-smoking lung cancer is critical to identifying new opportunities for intervention and addressing the global burden of lung cancer.","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133809580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Jassem, A. Kowalczyk, Aleksander Biesiada, R. Duchnowska, R. Dziadziuszko, Agnieszka Masztalerz-Migas, A. Kawecki, M. Krzakowski, P. Potemski, P. Rutkowski, P. Wysocki
{"title":"Post-treatment follow-up in common solid malignancies: expert panel recommendations","authors":"J. Jassem, A. Kowalczyk, Aleksander Biesiada, R. Duchnowska, R. Dziadziuszko, Agnieszka Masztalerz-Migas, A. Kawecki, M. Krzakowski, P. Potemski, P. Rutkowski, P. Wysocki","doi":"10.5603/njo.a2022.0058","DOIUrl":"https://doi.org/10.5603/njo.a2022.0058","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115602965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deeply located Merkel cell carcinoma","authors":"R. Robak, T. Wojewoda, W. Wysocki","doi":"10.5603/njo.2022.0059","DOIUrl":"https://doi.org/10.5603/njo.2022.0059","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"181 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114266760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna Kufel-Grabowska, S. Katarzyński, S. Szmit, M. Bartoszkiewicz, M. Litwiniuk
{"title":"Cardiotoxicity in patients with early breast cancer treated with adjuvant trastuzumab","authors":"Joanna Kufel-Grabowska, S. Katarzyński, S. Szmit, M. Bartoszkiewicz, M. Litwiniuk","doi":"10.5603/njo.a2022.0047","DOIUrl":"https://doi.org/10.5603/njo.a2022.0047","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117296056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SDH-deficient gastrointestinal stromal tumours","authors":"P. Rutkowski, K. Seliga, M. Debiec-Rychter","doi":"10.5603/njo.2022.0052","DOIUrl":"https://doi.org/10.5603/njo.2022.0052","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"303 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132530329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kajetan Kiełbowski, Estera Bakinowska, Przemysław Dymek, Sandra Sienkiewicz, Tomasz Błaszkowski, Maciej Romanowski
Advanced gastric cancer (AGC) is characterized by high mortality. The survival is estimated as 14.2 months. The treatment of choice in the early stages of GC is surgery. Due to high potential of malignancy, postoperative chemotherapy is usually administered. Novel methods of treatment involve immunotherapeutic agents (IA). The new therapies seem to be a hopeful perspective for patients with advanced GC. In this review, we present the outcomes of clinical trials in GC treatment with IA and their mechanisms of action. Furthermore, we present the benefits and shortcomings of immunotherapy and describe potential directions for future research.
{"title":"Immunotherapeutics and other anticancer agents in the management of advanced gastric cancer","authors":"Kajetan Kiełbowski, Estera Bakinowska, Przemysław Dymek, Sandra Sienkiewicz, Tomasz Błaszkowski, Maciej Romanowski","doi":"10.5603/njo.a2022.0043","DOIUrl":"https://doi.org/10.5603/njo.a2022.0043","url":null,"abstract":"Advanced gastric cancer (AGC) is characterized by high mortality. The survival is estimated as 14.2 months. The treatment of choice in the early stages of GC is surgery. Due to high potential of malignancy, postoperative chemotherapy is usually administered. Novel methods of treatment involve immunotherapeutic agents (IA). The new therapies seem to be a hopeful perspective for patients with advanced GC. In this review, we present the outcomes of clinical trials in GC treatment with IA and their mechanisms of action. Furthermore, we present the benefits and shortcomings of immunotherapy and describe potential directions for future research.","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124760201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of metastatic uveal melanoma","authors":"M. Polaczek, H. Koseła-Paterczyk","doi":"10.5603/njo.a2022.0057","DOIUrl":"https://doi.org/10.5603/njo.a2022.0057","url":null,"abstract":"","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114629880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Suwiński, M. Zeman, I. Debosz-Suwinska, A. Idasiak
Selection of optimal perioperative treatment for rectal cancer remains a subject of controversies. Recently established new rationales for use of short-course preoperative radiotherapy (SCRT- 25 Gy in 5 fractions), instead of standard long-course preoperative radio-chemotherapy (LCRT-CT), are presented and discussed in the present review. New data suggest that short-course radiotherapy combined with 6 cycles of CAPOX, or 9 of FOLFOX4 may be considered, at present, the best option for perioperative treatment of high-risk rectal cancer. However, there is a clear need to further optimize preoperative treatment using rapidly evolving markers of treatment response, including microsatellite instability and targetable or predictive tumour mutations.
{"title":"Short-course radiotherapy as a part of total neoadjuvant therapy for locally advanced rectal cancer – a new standard?","authors":"R. Suwiński, M. Zeman, I. Debosz-Suwinska, A. Idasiak","doi":"10.5603/njo.a2022.0056","DOIUrl":"https://doi.org/10.5603/njo.a2022.0056","url":null,"abstract":"Selection of optimal perioperative treatment for rectal cancer remains a subject of controversies. Recently established new rationales for use of short-course preoperative radiotherapy (SCRT- 25 Gy in 5 fractions), instead of standard long-course preoperative radio-chemotherapy (LCRT-CT), are presented and discussed in the present review. New data suggest that short-course radiotherapy combined with 6 cycles of CAPOX, or 9 of FOLFOX4 may be considered, at present, the best option for perioperative treatment of high-risk rectal cancer. However, there is a clear need to further optimize preoperative treatment using rapidly evolving markers of treatment response, including microsatellite instability and targetable or predictive tumour mutations.","PeriodicalId":130080,"journal":{"name":"Nowotwory. Journal of Oncology","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133898597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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